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Implement empirical p-value formula by comparing with non-targeting distribution #83

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abearab opened this issue Jul 26, 2024 · 2 comments
Open
Tracked by #12

Implement empirical p-value formula by comparing with non-targeting distribution #83

abearab opened this issue Jul 26, 2024 · 2 comments
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@AshirBorah @abearab
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analysis A data analysis step or task help wanted Extra attention is needed
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Benchmark ScreenP...

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abearab commented Jul 26, 2024

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@abearab abearab mentioned this issue Jul 26, 2024
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@abearab abearab added help wanted Extra attention is needed analysis A data analysis step or task labels Jul 26, 2024
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abearab commented Sep 25, 2024

garrett:

(re: multiple testing correction for Abe, I think you should just kind of forget it. The goal would be FDR control, and I don't think any procedure can do better than the empirical FDR provided by the negative control distribution.)

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abearab commented Oct 24, 2024

https://www.cell.com/ajhg/fulltext/S0002-9297(07)60491-1

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analysis A data analysis step or task help wanted Extra attention is needed
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Benchmark ScreenPro2 in CRISPR screen...
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@AshirBorah @abearab