diff --git a/Microsoft.Azure.Cosmos/src/CosmosClientOptions.cs b/Microsoft.Azure.Cosmos/src/CosmosClientOptions.cs
index 6bfc65a005..35dae71952 100644
--- a/Microsoft.Azure.Cosmos/src/CosmosClientOptions.cs
+++ b/Microsoft.Azure.Cosmos/src/CosmosClientOptions.cs
@@ -60,7 +60,8 @@ public class CosmosClientOptions
         /// </summary>
         private int gatewayModeMaxConnectionLimit;
         private CosmosSerializationOptions serializerOptions;
-        private CosmosSerializer serializerInternal;
+        private CosmosSerializer serializerInternal;
+        private System.Text.Json.JsonSerializerOptions stjSerializerOptions;
 
         private ConnectionMode connectionMode;
         private Protocol connectionProtocol;
@@ -392,6 +393,44 @@ public ConnectionMode ConnectionMode
         /// <seealso cref="ItemRequestOptions.EnableContentResponseOnWrite"/>
         /// <seealso cref="TransactionalBatchItemRequestOptions.EnableContentResponseOnWrite"/>
         public bool? EnableContentResponseOnWrite { get; set; }
+
+        /// <summary>
+        /// Sets the <see cref="System.Text.Json.JsonSerializerOptions"/> for the System.Text.Json serializer.
+        /// Note that if this option is provided, then the SDK will use the System.Text.Json as the default serializer and set
+        /// the serializer options as the constructor args.
+        /// </summary>
+        /// <example>
+        /// An example on how to configure the System.Text.Json serializer options to ignore null values
+        /// <code language="c#">
+        /// <![CDATA[
+        /// CosmosClientOptions clientOptions = new CosmosClientOptions()
+        /// {
+        ///     UseSystemTextJsonSerializerWithOptions = new System.Text.Json.JsonSerializerOptions()
+        ///     {
+        ///         DefaultIgnoreCondition = System.Text.Json.Serialization.JsonIgnoreCondition.WhenWritingNull,
+        ///     }
+        /// };
+        /// 
+        /// CosmosClient client = new CosmosClient("endpoint", "key", clientOptions);
+        /// ]]>
+        /// </code>
+        /// </example>
+        public System.Text.Json.JsonSerializerOptions UseSystemTextJsonSerializerWithOptions
+        {
+            get => this.stjSerializerOptions;
+            set
+            {
+                if (this.Serializer != null || this.SerializerOptions != null)
+                {
+                    throw new ArgumentException(
+                        $"{nameof(this.UseSystemTextJsonSerializerWithOptions)} is not compatible with {nameof(this.Serializer)} or {nameof(this.SerializerOptions)}. Only one can be set.  ");
+                }
+
+                this.stjSerializerOptions = value;
+                this.serializerInternal = new CosmosSystemTextJsonSerializer(
+                    this.stjSerializerOptions);
+            }
+        }
 
         /// <summary>
         /// Gets or sets the advanced replica selection flag. The advanced replica selection logic keeps track of the replica connection
@@ -543,10 +582,10 @@ public CosmosSerializationOptions SerializerOptions
             get => this.serializerOptions;
             set
             {
-                if (this.Serializer != null)
+                if (this.Serializer != null || this.UseSystemTextJsonSerializerWithOptions != null)
                 {
                     throw new ArgumentException(
-                        $"{nameof(this.SerializerOptions)} is not compatible with {nameof(this.Serializer)}. Only one can be set.  ");
+                        $"{nameof(this.SerializerOptions)} is not compatible with {nameof(this.Serializer)} or {nameof(this.UseSystemTextJsonSerializerWithOptions)}. Only one can be set.  ");
                 }
 
                 this.serializerOptions = value;
@@ -578,10 +617,10 @@ public CosmosSerializer Serializer
             get => this.serializerInternal;
             set
             {
-                if (this.SerializerOptions != null)
+                if (this.SerializerOptions != null || this.UseSystemTextJsonSerializerWithOptions != null)
                 {
                     throw new ArgumentException(
-                        $"{nameof(this.Serializer)} is not compatible with {nameof(this.SerializerOptions)}. Only one can be set.  ");
+                        $"{nameof(this.Serializer)} is not compatible with {nameof(this.SerializerOptions)} or {nameof(this.UseSystemTextJsonSerializerWithOptions)}. Only one can be set.  ");
                 }
 
                 this.serializerInternal = value;
diff --git a/Microsoft.Azure.Cosmos/src/Fluent/CosmosClientBuilder.cs b/Microsoft.Azure.Cosmos/src/Fluent/CosmosClientBuilder.cs
index 43232aa422..c614068fae 100644
--- a/Microsoft.Azure.Cosmos/src/Fluent/CosmosClientBuilder.cs
+++ b/Microsoft.Azure.Cosmos/src/Fluent/CosmosClientBuilder.cs
@@ -646,7 +646,22 @@ public CosmosClientBuilder WithContentResponseOnWrite(bool contentResponseOnWrit
         {
             this.clientOptions.EnableContentResponseOnWrite = contentResponseOnWrite;
             return this;
-        }
+        }
+
+        /// <summary>
+        /// Configures the <see cref="CosmosClientBuilder"/> to use System.Text.Json for serialization.
+        /// Use <see cref="System.Text.Json.JsonSerializerOptions" /> to use System.Text.Json with a default configuration.
+        /// If no options are specified, Newtonsoft.Json will be used for serialization instead.
+        /// </summary>
+        /// <param name="serializerOptions">An instance of <see cref="System.Text.Json.JsonSerializerOptions"/>
+        /// containing the system text json serializer options.</param>
+        /// <returns>The <see cref="CosmosClientBuilder"/> object</returns>
+        public CosmosClientBuilder WithSystemTextJsonSerializerOptions(
+            System.Text.Json.JsonSerializerOptions serializerOptions)
+        {
+            this.clientOptions.UseSystemTextJsonSerializerWithOptions = serializerOptions;
+            return this;
+        }
 
         /// <summary>
         /// The event handler to be invoked before the request is sent.
@@ -725,7 +740,7 @@ internal CosmosClientBuilder WithPartitionLevelFailoverEnabled()
         {
             this.clientOptions.EnablePartitionLevelFailover = true;
             return this;
-        }
+        }
 
         /// <summary>
         /// Enables SDK to inject fault. Used for testing applications.  
diff --git a/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.EmulatorTests/Linq/LinqAggregateCustomSerializationBaseline.cs b/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.EmulatorTests/Linq/LinqAggregateCustomSerializationBaseline.cs
index ac686b31e1..54af230979 100644
--- a/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.EmulatorTests/Linq/LinqAggregateCustomSerializationBaseline.cs
+++ b/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.EmulatorTests/Linq/LinqAggregateCustomSerializationBaseline.cs
@@ -29,7 +29,6 @@ public class LinqAggregateCustomSerializationBaseline : BaselineTests<LinqAggreg
         private static Cosmos.Database testDb;
         private static Container testContainer;
 
-        private static CosmosSerializer stjCosmosSerializer;
         private static CosmosClient stjClient;
         private static Cosmos.Database testDbSTJ;
         private static Container testContainerSTJ;
@@ -64,10 +63,10 @@ public async static Task Initialize(TestContext textContext)
             testDb = await client.CreateDatabaseAsync(dbName);
             testContainer = testDb.CreateContainerAsync(new ContainerProperties(id: Guid.NewGuid().ToString(), partitionKeyPath: "/Pk")).Result;
 
-            stjCosmosSerializer = new CosmosSystemTextJsonSerializer(new JsonSerializerOptions());
-
             stjClient = TestCommon.CreateCosmosClient((cosmosClientBuilder)
-                => cosmosClientBuilder.WithCustomSerializer(stjCosmosSerializer));
+                => cosmosClientBuilder.WithSystemTextJsonSerializerOptions(
+                    new JsonSerializerOptions()),
+                    useCustomSeralizer: false);
 
             // Set a callback to get the handle of the last executed query to do the verification
             // This is neede because aggregate queries return type is a scalar so it can't be used 
diff --git a/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.EmulatorTests/LinqTranslationWithCustomSerializerBaseline.cs b/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.EmulatorTests/LinqTranslationWithCustomSerializerBaseline.cs
index 1224f48074..48aed543bf 100644
--- a/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.EmulatorTests/LinqTranslationWithCustomSerializerBaseline.cs
+++ b/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.EmulatorTests/LinqTranslationWithCustomSerializerBaseline.cs
@@ -57,7 +57,10 @@ public async static Task Initialize(TestContext textContext)
             TestDb = await CosmosClient.CreateDatabaseAsync(dbName);
 
             CosmosDefaultSTJClient = TestCommon.CreateCosmosClient((cosmosClientBuilder)
-                => cosmosClientBuilder.WithCustomSerializer(new CosmosSystemTextJsonSerializer(new JsonSerializerOptions())));
+                => cosmosClientBuilder
+                    .WithSystemTextJsonSerializerOptions(
+                        new JsonSerializerOptions()),
+                useCustomSeralizer: false);
 
             string dbNameSTJ = $"{nameof(LinqTranslationBaselineTests)}-{Guid.NewGuid():N}";
             TestDbSTJDefault = await CosmosDefaultSTJClient.CreateDatabaseAsync(dbNameSTJ);
diff --git a/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/Contracts/DotNetSDKAPI.json b/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/Contracts/DotNetSDKAPI.json
index 89074f0fef..2cc3fd8de5 100644
--- a/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/Contracts/DotNetSDKAPI.json
+++ b/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/Contracts/DotNetSDKAPI.json
@@ -2988,6 +2988,16 @@
           ],
           "MethodInfo": "System.String get_ApplicationRegion();IsAbstract:False;IsStatic:False;IsVirtual:False;IsGenericMethod:False;IsConstructor:False;IsFinal:False;"
         },
+        "System.Text.Json.JsonSerializerOptions get_UseSystemTextJsonSerializerWithOptions()": {
+          "Type": "Method",
+          "Attributes": [],
+          "MethodInfo": "System.Text.Json.JsonSerializerOptions get_UseSystemTextJsonSerializerWithOptions();IsAbstract:False;IsStatic:False;IsVirtual:False;IsGenericMethod:False;IsConstructor:False;IsFinal:False;"
+        },
+        "System.Text.Json.JsonSerializerOptions UseSystemTextJsonSerializerWithOptions": {
+          "Type": "Property",
+          "Attributes": [],
+          "MethodInfo": "System.Text.Json.JsonSerializerOptions UseSystemTextJsonSerializerWithOptions;CanRead:True;CanWrite:True;System.Text.Json.JsonSerializerOptions get_UseSystemTextJsonSerializerWithOptions();IsAbstract:False;IsStatic:False;IsVirtual:False;IsGenericMethod:False;IsConstructor:False;IsFinal:False;Void set_UseSystemTextJsonSerializerWithOptions(System.Text.Json.JsonSerializerOptions);IsAbstract:False;IsStatic:False;IsVirtual:False;IsGenericMethod:False;IsConstructor:False;IsFinal:False;"
+        },
         "System.TimeSpan get_RequestTimeout()[System.Runtime.CompilerServices.CompilerGeneratedAttribute()]": {
           "Type": "Method",
           "Attributes": [
@@ -3165,6 +3175,11 @@
           ],
           "MethodInfo": "Void set_TokenCredentialBackgroundRefreshInterval(System.Nullable`1[System.TimeSpan]);IsAbstract:False;IsStatic:False;IsVirtual:False;IsGenericMethod:False;IsConstructor:False;IsFinal:False;"
         },
+        "Void set_UseSystemTextJsonSerializerWithOptions(System.Text.Json.JsonSerializerOptions)": {
+          "Type": "Method",
+          "Attributes": [],
+          "MethodInfo": "Void set_UseSystemTextJsonSerializerWithOptions(System.Text.Json.JsonSerializerOptions);IsAbstract:False;IsStatic:False;IsVirtual:False;IsGenericMethod:False;IsConstructor:False;IsFinal:False;"
+        },
         "Void set_WebProxy(System.Net.IWebProxy)": {
           "Type": "Method",
           "Attributes": [],
@@ -4737,6 +4752,11 @@
           "Attributes": [],
           "MethodInfo": "Microsoft.Azure.Cosmos.Fluent.CosmosClientBuilder WithSerializerOptions(Microsoft.Azure.Cosmos.CosmosSerializationOptions);IsAbstract:False;IsStatic:False;IsVirtual:False;IsGenericMethod:False;IsConstructor:False;IsFinal:False;"
         },
+        "Microsoft.Azure.Cosmos.Fluent.CosmosClientBuilder WithSystemTextJsonSerializerOptions(System.Text.Json.JsonSerializerOptions)": {
+          "Type": "Method",
+          "Attributes": [],
+          "MethodInfo": "Microsoft.Azure.Cosmos.Fluent.CosmosClientBuilder WithSystemTextJsonSerializerOptions(System.Text.Json.JsonSerializerOptions);IsAbstract:False;IsStatic:False;IsVirtual:False;IsGenericMethod:False;IsConstructor:False;IsFinal:False;"
+        },
         "Microsoft.Azure.Cosmos.Fluent.CosmosClientBuilder WithThrottlingRetryOptions(System.TimeSpan, Int32)": {
           "Type": "Method",
           "Attributes": [],
diff --git a/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/CosmosClientOptionsUnitTests.cs b/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/CosmosClientOptionsUnitTests.cs
index 293c3b14ab..c27ca8abf1 100644
--- a/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/CosmosClientOptionsUnitTests.cs
+++ b/Microsoft.Azure.Cosmos/tests/Microsoft.Azure.Cosmos.Tests/CosmosClientOptionsUnitTests.cs
@@ -13,6 +13,7 @@ namespace Microsoft.Azure.Cosmos.Tests
     using System.Net.Security;
     using System.Security.Cryptography;
     using System.Security.Cryptography.X509Certificates;
+    using System.Text;
     using global::Azure.Core;
     using Microsoft.Azure.Cosmos.Fluent;
     using Microsoft.Azure.Documents;
@@ -476,6 +477,26 @@ public void UserAgentContainsEnvironmentInformation()
             Assert.AreEqual(userAgentSuffix, connectionPolicy.UserAgentSuffix);
             Assert.IsTrue(connectionPolicy.UserAgentContainer.UserAgent.StartsWith(expectedValue));
             Assert.IsTrue(connectionPolicy.UserAgentContainer.UserAgent.EndsWith(userAgentSuffix));
+        }
+
+        [TestMethod]
+        public void ValidateThatCustomSerializerGetsOverriddenWhenSTJSerializerEnabled()
+        {
+            CosmosClientOptions options = new CosmosClientOptions()
+            {
+                UseSystemTextJsonSerializerWithOptions = new System.Text.Json.JsonSerializerOptions()
+                {
+                    PropertyNamingPolicy = System.Text.Json.JsonNamingPolicy.CamelCase,
+                }
+            };
+
+            CosmosClient client = new(
+                "https://fake-account.documents.azure.com:443/",
+                Convert.ToBase64String(Encoding.UTF8.GetBytes(Guid.NewGuid().ToString())),
+                options
+            );
+
+            Assert.AreEqual(typeof(CosmosSystemTextJsonSerializer), client.ClientOptions.Serializer.GetType());
         }
 
         [TestMethod]
@@ -500,8 +521,58 @@ public void ThrowOnCustomSerializerWithSerializerOptions()
             };
 
             options.Serializer = new CosmosJsonDotNetSerializer();
-        }
-
+        }
+
+        [TestMethod]
+        [DataRow(false, DisplayName = "Test when the client options order is maintained")]
+        [DataRow(true, DisplayName = "Test when the client options order is reversed")]
+        [ExpectedException(typeof(ArgumentException))]
+        public void ThrowOnCustomSerializerWithSTJSerializerEnabled(
+            bool reverseOrder)
+        {
+            if (reverseOrder)
+            {
+                CosmosClientOptions options = new CosmosClientOptions()
+                {
+                    Serializer = new CosmosJsonDotNetSerializer(),
+                    UseSystemTextJsonSerializerWithOptions = new System.Text.Json.JsonSerializerOptions(),
+                };
+            }
+            else
+            {
+                CosmosClientOptions options = new CosmosClientOptions()
+                {
+                    UseSystemTextJsonSerializerWithOptions = new System.Text.Json.JsonSerializerOptions(),
+                    Serializer = new CosmosJsonDotNetSerializer(),
+                };
+            }
+        }
+
+        [TestMethod]
+        [DataRow(false, DisplayName = "Test when the client options order is maintained")]
+        [DataRow(true, DisplayName = "Test when the client options order is reversed")]
+        [ExpectedException(typeof(ArgumentException))]
+        public void ThrowOnSerializerOptionsWithSTJSerializerEnabled(
+            bool reverseOrder)
+        {
+            if (reverseOrder)
+            {
+                CosmosClientOptions options = new CosmosClientOptions()
+                {
+                    SerializerOptions = new CosmosSerializationOptions(),
+                    UseSystemTextJsonSerializerWithOptions = new System.Text.Json.JsonSerializerOptions(),
+                };
+            }
+            else
+            {
+                CosmosClientOptions options = new CosmosClientOptions()
+                {
+                    UseSystemTextJsonSerializerWithOptions = new System.Text.Json.JsonSerializerOptions(),
+                    SerializerOptions = new CosmosSerializationOptions(),
+                };
+            }
+        }
+
         [TestMethod]
         [ExpectedException(typeof(ArgumentNullException))]
         public void ThrowOnNullTokenCredential()