Failed Cholesky decomposition in decomposeMatrix

[bebatut]

Hi,

When I try to run CONCOCT on one of my sample (work on a 2nd one), it failed with Failed Cholesky decomposition in decomposeMatrix.
I do not understand the error, what could cause it and how to fix it.
Any idea how to debug?

Thanks

Bérénice

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Details

Command:

$ concoct --coverage_file 'coverage' --composition_file 'composition.fa' --clusters 400 --kmer_length 4 --threads 48 --length_threshold 1000 --read_length 100 --total_percentage_pca 100 --basename 'outdir/' --seed 1 --iterations 500   --no_original_data

with

• Assembly from MEGAHIT
• coverage generated using concoct_coverage_table.py (default values)
• composition.fa generated using cut_up_fasta.py (default values)