diff --git a/blosc/CMakeLists.txt b/blosc/CMakeLists.txt
index 323281f5..e22561bc 100644
--- a/blosc/CMakeLists.txt
+++ b/blosc/CMakeLists.txt
@@ -37,6 +37,7 @@ if(BUILD_SHARED)
         $<INSTALL_INTERFACE:include>)
 endif()
 if(BUILD_STATIC)
+    add_compile_definitions(BUILD_STATIC)
     add_library(blosc2_static STATIC)
     # ALIAS for superbuilds that use Blosc2 as sub-project
     # must be the same as the NAMESPACE in Blosc2Targets
diff --git a/blosc/shuffle.c b/blosc/shuffle.c
index 62587639..ca9e3747 100644
--- a/blosc/shuffle.c
+++ b/blosc/shuffle.c
@@ -52,7 +52,7 @@
 
 // __builtin_cpu_supports() fixed in GCC 8: https://gcc.gnu.org/bugzilla/show_bug.cgi?id=85100
 // Also, clang added support for it in clang 10 at very least (and possibly since 3.8)
-#if (defined(__clang__) && (__clang_major__ >= 10)) || \
+#if (defined(__clang__) && (__clang_major__ >= 10)) && !(defined(__APPLE__) && defined(__x86_64__) && defined(BUILD_STATIC)) || \
     (defined(__GNUC__) && defined(__GNUC_MINOR__) && __GNUC__ >= 8)
 #define HAVE_CPU_FEAT_INTRIN
 #endif