diff --git a/src/python/pants/backend/python/tasks/python_binary_create.py b/src/python/pants/backend/python/tasks/python_binary_create.py
index 0aa46037489..dc30234b909 100644
--- a/src/python/pants/backend/python/tasks/python_binary_create.py
+++ b/src/python/pants/backend/python/tasks/python_binary_create.py
@@ -143,7 +143,7 @@ def _create_binary(self, binary_tgt, results_dir):
 
       # Add global and target-level interpreter compatibility constraints to pex info.
       pex_builder.add_interpreter_constraints_from(constraint_tgts)
-      pex_builder.add_interpreter_constraints(PythonSetup.global_instance().interpreter_constraints)
+      pex_builder.add_interpreter_constraint(PythonSetup.global_instance().interpreter_constraints)
 
       # Dump everything into the builder's chroot.
       for tgt in source_tgts: