diff --git a/CHANGELOG.rst b/CHANGELOG.rst
index 257ab279..28dcc861 100644
--- a/CHANGELOG.rst
+++ b/CHANGELOG.rst
@@ -7,6 +7,7 @@ Release 2.0.6
 * `scikit-ued` is being re-licensed from the MIT license to the GPLv3 license.
 * The `fast` argument to `skued.align` and `skued.ialign` has been deprecated. Its value has no effect anymore.
 * Official support for Python 3.9.
+* Removed explicit requirement for the `tifffile` package.
 
 Release 2.0.5
 -------------
diff --git a/appveyor.yml b/appveyor.yml
index ad14ac2c..8b56080d 100644
--- a/appveyor.yml
+++ b/appveyor.yml
@@ -14,7 +14,7 @@ environment:
                         # to the matrix section.
       TEST_CMD: "python -m unittest discover --verbose"
       CONDA_CHANNELS: "default conda-forge"
-      CONDA_DEPENDENCIES: "numpy scipy cython scikit-image crystals tifffile pywavelets npstreams pyyaml"
+      CONDA_DEPENDENCIES: "numpy scipy cython scikit-image crystals pywavelets npstreams pyyaml"
       PIP_DEPENDENCIES: ""
 
   matrix:
diff --git a/requirements.txt b/requirements.txt
index 181ba883..adee2fe0 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -4,6 +4,5 @@ numpy        >= 1.15, < 2
 pywavelets   >= 1.0.0
 scikit-image >= 0.17, <1
 scipy        >= 1.0.0
-tifffile     >= 0.13
 pyyaml       >= 3.1
 matplotlib   >= 3.0.0, <4
\ No newline at end of file
diff --git a/skued/io/io.py b/skued/io/io.py
index 51feb0ab..42aa71b8 100644
--- a/skued/io/io.py
+++ b/skued/io/io.py
@@ -2,8 +2,6 @@
 
 from pathlib import Path
 
-import tifffile
-
 from .dm import dmread
 from .merlin import mibread
 
@@ -40,9 +38,7 @@ def diffread(fname):
     """
     fname = str(fname)  # In case of pathlib.Path
 
-    if fname.endswith(("tiff", "tif")):
-        return tifffile.imread(fname)
-    elif fname.endswith(".mib"):
+    if fname.endswith(".mib"):
         return mibread(fname)
     elif fname.endswith((".dm3", ".dm4")):
         return dmread(fname)