diff --git a/Marlin/Configuration_adv.h b/Marlin/Configuration_adv.h
index 930e931d3262..c8d65773920b 100644
--- a/Marlin/Configuration_adv.h
+++ b/Marlin/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/Marlin.h b/Marlin/Marlin.h
index 4a07513b0adb..2719489695ef 100644
--- a/Marlin/Marlin.h
+++ b/Marlin/Marlin.h
@@ -134,7 +134,7 @@ void idle(
 
 void manage_inactivity(bool ignore_stepper_queue = false);
 
-#if ENABLED(DUAL_X_CARRIAGE)
+#if ENABLED(DUAL_X_CARRIAGE) || ENABLED(DUAL_NOZZLE_DUPLICATION_MODE)
   extern bool extruder_duplication_enabled;
 #endif
 
diff --git a/Marlin/Marlin_main.cpp b/Marlin/Marlin_main.cpp
index 3e2c641acfa9..2966162dc85a 100644
--- a/Marlin/Marlin_main.cpp
+++ b/Marlin/Marlin_main.cpp
@@ -1392,6 +1392,10 @@ XYZ_CONSTS_FROM_CONFIG(float, max_length,     MAX_LENGTH);
 XYZ_CONSTS_FROM_CONFIG(float, home_bump_mm,   HOME_BUMP_MM);
 XYZ_CONSTS_FROM_CONFIG(signed char, home_dir, HOME_DIR);
 
+#if ENABLED(DUAL_X_CARRIAGE) || ENABLED(DUAL_NOZZLE_DUPLICATION_MODE)
+  bool extruder_duplication_enabled = false; // Used in Dual X mode 2
+#endif
+
 #if ENABLED(DUAL_X_CARRIAGE)
 
   #define DXC_FULL_CONTROL_MODE 0
@@ -1423,7 +1427,6 @@ XYZ_CONSTS_FROM_CONFIG(signed char, home_dir, HOME_DIR);
   static millis_t delayed_move_time = 0; // used in mode 1
   static float duplicate_extruder_x_offset = DEFAULT_DUPLICATION_X_OFFSET; // used in mode 2
   static float duplicate_extruder_temp_offset = 0; // used in mode 2
-  bool extruder_duplication_enabled = false; // used in mode 2
 
 #endif //DUAL_X_CARRIAGE
 
@@ -2820,12 +2823,13 @@ inline void gcode_G4() {
     current_position[X_AXIS] = current_position[Y_AXIS] = 0.0;
     sync_plan_position();
 
-    #if ENABLED(DUAL_X_CARRIAGE)
-      int x_axis_home_dir = x_home_dir(active_extruder);
-      extruder_duplication_enabled = false;
-    #else
-      int x_axis_home_dir = home_dir(X_AXIS);
-    #endif
+    int x_axis_home_dir =
+      #if ENABLED(DUAL_X_CARRIAGE)
+        x_home_dir(active_extruder)
+      #else
+        home_dir(X_AXIS)
+      #endif
+    ;
 
     float mlx = max_length(X_AXIS),
           mly = max_length(Y_AXIS),
@@ -2878,6 +2882,10 @@ inline void gcode_G28() {
     tool_change(0, 0, true);
   #endif
 
+  #if ENABLED(DUAL_X_CARRIAGE) || ENABLED(DUAL_NOZZLE_DUPLICATION_MODE)
+    extruder_duplication_enabled = false;
+  #endif
+
   /**
    * For mesh bed leveling deactivate the mesh calculations, will be turned
    * on again when homing all axis
@@ -2996,7 +3004,6 @@ inline void gcode_G28() {
     if (home_all_axis || homeX) {
       #if ENABLED(DUAL_X_CARRIAGE)
         int tmp_extruder = active_extruder;
-        extruder_duplication_enabled = false;
         active_extruder = !active_extruder;
         HOMEAXIS(X);
         inactive_extruder_x_pos = current_position[X_AXIS];
@@ -6473,7 +6480,17 @@ inline void gcode_M503() {
     delayed_move_time = 0;
   }
 
-#endif // DUAL_X_CARRIAGE
+#elif ENABLED(DUAL_NOZZLE_DUPLICATION_MODE)
+
+  inline void gcode_M605() {
+    stepper.synchronize();
+    extruder_duplication_enabled = code_seen('S') && code_value_int() == 2;
+    SERIAL_ECHO_START;
+    SERIAL_ECHOPAIR(MSG_DUPLICATION_MODE, extruder_duplication_enabled ? MSG_ON : MSG_OFF);
+    SERIAL_EOL;
+  }
+
+#endif // M605
 
 #if ENABLED(LIN_ADVANCE)
   /**
diff --git a/Marlin/SanityCheck.h b/Marlin/SanityCheck.h
index 174f3b43045d..5eea066a6fa4 100644
--- a/Marlin/SanityCheck.h
+++ b/Marlin/SanityCheck.h
@@ -175,7 +175,7 @@
  */
 #if ENABLED(SWITCHING_EXTRUDER)
   #if ENABLED(DUAL_X_CARRIAGE)
-    #error "SINGLENOZZLE and DUAL_X_CARRIAGE are incompatible."
+    #error "SWITCHING_EXTRUDER and DUAL_X_CARRIAGE are incompatible."
   #elif EXTRUDERS != 2
     #error "SWITCHING_EXTRUDER requires exactly 2 EXTRUDERS."
   #elif NUM_SERVOS < 1
@@ -572,6 +572,23 @@
   #error "TEMP_SENSOR_1 is required with TEMP_SENSOR_1_AS_REDUNDANT."
 #endif
 
+/**
+ * Basic 2-nozzle duplication mode
+ */
+#if ENABLED(DUAL_NOZZLE_DUPLICATION_MODE)
+  #if HOTENDS != 2
+    #error "DUAL_NOZZLE_DUPLICATION_MODE requires exactly 2 hotends."
+  #elif ENABLED(DUAL_X_CARRIAGE)
+    #error "DUAL_NOZZLE_DUPLICATION_MODE is incompatible with DUAL_X_CARRIAGE."
+  #elif ENABLED(SINGLENOZZLE)
+    #error "DUAL_NOZZLE_DUPLICATION_MODE is incompatible with SINGLENOZZLE."
+  #elif ENABLED(MIXING_EXTRUDER)
+    #error "DUAL_NOZZLE_DUPLICATION_MODE is incompatible with MIXING_EXTRUDER."
+  #elif ENABLED(SWITCHING_EXTRUDER)
+    #error "DUAL_NOZZLE_DUPLICATION_MODE is incompatible with SWITCHING_EXTRUDER."
+  #endif
+#endif
+
 /**
  * Test Extruder Pins
  */
diff --git a/Marlin/example_configurations/Cartesio/Configuration_adv.h b/Marlin/example_configurations/Cartesio/Configuration_adv.h
index 9207b5703afb..86a14793cadb 100644
--- a/Marlin/example_configurations/Cartesio/Configuration_adv.h
+++ b/Marlin/example_configurations/Cartesio/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/Felix/Configuration_adv.h b/Marlin/example_configurations/Felix/Configuration_adv.h
index 3f0729b6c99c..d4eed80f3ad6 100644
--- a/Marlin/example_configurations/Felix/Configuration_adv.h
+++ b/Marlin/example_configurations/Felix/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/Hephestos/Configuration_adv.h b/Marlin/example_configurations/Hephestos/Configuration_adv.h
index af6bce8053fd..6dc51d6b1419 100644
--- a/Marlin/example_configurations/Hephestos/Configuration_adv.h
+++ b/Marlin/example_configurations/Hephestos/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/Hephestos_2/Configuration_adv.h b/Marlin/example_configurations/Hephestos_2/Configuration_adv.h
index bfb6b16c71bd..501541bd9a85 100644
--- a/Marlin/example_configurations/Hephestos_2/Configuration_adv.h
+++ b/Marlin/example_configurations/Hephestos_2/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/K8200/Configuration_adv.h b/Marlin/example_configurations/K8200/Configuration_adv.h
index 3703ce1ccc7a..a822c9bf50c3 100644
--- a/Marlin/example_configurations/K8200/Configuration_adv.h
+++ b/Marlin/example_configurations/K8200/Configuration_adv.h
@@ -335,7 +335,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/K8400/Configuration_adv.h b/Marlin/example_configurations/K8400/Configuration_adv.h
index 11fdbdb3c2ea..8b0fd6d3850f 100644
--- a/Marlin/example_configurations/K8400/Configuration_adv.h
+++ b/Marlin/example_configurations/K8400/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/RigidBot/Configuration_adv.h b/Marlin/example_configurations/RigidBot/Configuration_adv.h
index 3c09682603a8..c2fcf92688dd 100644
--- a/Marlin/example_configurations/RigidBot/Configuration_adv.h
+++ b/Marlin/example_configurations/RigidBot/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/SCARA/Configuration_adv.h b/Marlin/example_configurations/SCARA/Configuration_adv.h
index 6a0dea8021b3..42045d7b8e67 100644
--- a/Marlin/example_configurations/SCARA/Configuration_adv.h
+++ b/Marlin/example_configurations/SCARA/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/TAZ4/Configuration_adv.h b/Marlin/example_configurations/TAZ4/Configuration_adv.h
index fe9b6ba36fdc..9a7dcf60216a 100644
--- a/Marlin/example_configurations/TAZ4/Configuration_adv.h
+++ b/Marlin/example_configurations/TAZ4/Configuration_adv.h
@@ -337,7 +337,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/WITBOX/Configuration_adv.h b/Marlin/example_configurations/WITBOX/Configuration_adv.h
index af6bce8053fd..6dc51d6b1419 100644
--- a/Marlin/example_configurations/WITBOX/Configuration_adv.h
+++ b/Marlin/example_configurations/WITBOX/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/delta/biv2.5/Configuration_adv.h b/Marlin/example_configurations/delta/biv2.5/Configuration_adv.h
index 173cacf4d03d..9dc856be7cb9 100644
--- a/Marlin/example_configurations/delta/biv2.5/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/biv2.5/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/delta/generic/Configuration_adv.h b/Marlin/example_configurations/delta/generic/Configuration_adv.h
index 51a2d2b0b11f..66877a67ecdd 100644
--- a/Marlin/example_configurations/delta/generic/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/generic/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h b/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h
index 90b3c68f0dd4..24cf11fab0e3 100644
--- a/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/kossel_mini/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h b/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h
index b8b94f8d4dd8..6ee22d84a75c 100644
--- a/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/kossel_pro/Configuration_adv.h
@@ -334,7 +334,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h b/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h
index 74bb7c5dc288..bd557707852e 100644
--- a/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h
+++ b/Marlin/example_configurations/delta/kossel_xl/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/makibox/Configuration_adv.h b/Marlin/example_configurations/makibox/Configuration_adv.h
index 6e8c6e6713ad..9413d9b0cf3b 100644
--- a/Marlin/example_configurations/makibox/Configuration_adv.h
+++ b/Marlin/example_configurations/makibox/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h b/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h
index f72daabc8062..752c24f698b0 100644
--- a/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h
+++ b/Marlin/example_configurations/tvrrug/Round2/Configuration_adv.h
@@ -329,7 +329,10 @@
 
 #define AXIS_RELATIVE_MODES {false, false, false, false}
 
-//By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
+// Allow duplication mode with a basic dual-nozzle extruder
+//#define DUAL_NOZZLE_DUPLICATION_MODE
+
+// By default pololu step drivers require an active high signal. However, some high power drivers require an active low signal as step.
 #define INVERT_X_STEP_PIN false
 #define INVERT_Y_STEP_PIN false
 #define INVERT_Z_STEP_PIN false
diff --git a/Marlin/language.h b/Marlin/language.h
index 093368333885..4e53c48903c0 100644
--- a/Marlin/language.h
+++ b/Marlin/language.h
@@ -159,6 +159,7 @@
 #define MSG_ENDSTOP_HIT                     "TRIGGERED"
 #define MSG_ENDSTOP_OPEN                    "open"
 #define MSG_HOTEND_OFFSET                   "Hotend offsets:"
+#define MSG_DUPLICATION_MODE                "Duplication mode: "
 
 #define MSG_SD_CANT_OPEN_SUBDIR             "Cannot open subdir "
 #define MSG_SD_INIT_FAIL                    "SD init fail"
diff --git a/Marlin/stepper_indirection.h b/Marlin/stepper_indirection.h
index 65fde23c1682..4052e395fd66 100644
--- a/Marlin/stepper_indirection.h
+++ b/Marlin/stepper_indirection.h
@@ -72,7 +72,7 @@
   #define X2_ENABLE_INIT SET_OUTPUT(X2_ENABLE_PIN)
   #define X2_ENABLE_WRITE(STATE) WRITE(X2_ENABLE_PIN,STATE)
   #define X2_ENABLE_READ READ(X_ENABLE_PIN)
-#endif // DUAL_X_CARRIAGE
+#endif
 
 // Y motor
 #define Y_STEP_INIT SET_OUTPUT(Y_STEP_PIN)
@@ -195,14 +195,14 @@
   #define NORM_E_DIR() { switch (current_block->active_extruder) { case 0: E0_DIR_WRITE(!INVERT_E0_DIR); break; case 1: E1_DIR_WRITE(!INVERT_E1_DIR); break; case 2: E2_DIR_WRITE(!INVERT_E2_DIR); } }
   #define REV_E_DIR() { switch (current_block->active_extruder) { case 0: E0_DIR_WRITE(INVERT_E0_DIR); break; case 1: E1_DIR_WRITE(INVERT_E1_DIR); break; case 2: E2_DIR_WRITE(INVERT_E2_DIR); } }
 #elif EXTRUDERS > 1
-  #if DISABLED(DUAL_X_CARRIAGE)
-    #define E_STEP_WRITE(v) { if (current_block->active_extruder == 0) { E0_STEP_WRITE(v); } else { E1_STEP_WRITE(v); } }
-    #define NORM_E_DIR() { if (current_block->active_extruder == 0) { E0_DIR_WRITE(!INVERT_E0_DIR); } else { E1_DIR_WRITE(!INVERT_E1_DIR); } }
-    #define REV_E_DIR() { if (current_block->active_extruder == 0) { E0_DIR_WRITE(INVERT_E0_DIR); } else { E1_DIR_WRITE(INVERT_E1_DIR); } }
-  #else
+  #if ENABLED(DUAL_X_CARRIAGE) || ENABLED(DUAL_NOZZLE_DUPLICATION_MODE)
     #define E_STEP_WRITE(v) { if (extruder_duplication_enabled) { E0_STEP_WRITE(v); E1_STEP_WRITE(v); } else if (current_block->active_extruder == 0) { E0_STEP_WRITE(v); } else { E1_STEP_WRITE(v); } }
     #define NORM_E_DIR() { if (extruder_duplication_enabled) { E0_DIR_WRITE(!INVERT_E0_DIR); E1_DIR_WRITE(!INVERT_E1_DIR); } else if (current_block->active_extruder == 0) { E0_DIR_WRITE(!INVERT_E0_DIR); } else { E1_DIR_WRITE(!INVERT_E1_DIR); } }
     #define REV_E_DIR() { if (extruder_duplication_enabled) { E0_DIR_WRITE(INVERT_E0_DIR); E1_DIR_WRITE(INVERT_E1_DIR); } else if (current_block->active_extruder == 0) { E0_DIR_WRITE(INVERT_E0_DIR); } else { E1_DIR_WRITE(INVERT_E1_DIR); } }
+  #else
+    #define E_STEP_WRITE(v) { if (current_block->active_extruder == 0) { E0_STEP_WRITE(v); } else { E1_STEP_WRITE(v); } }
+    #define NORM_E_DIR() { if (current_block->active_extruder == 0) { E0_DIR_WRITE(!INVERT_E0_DIR); } else { E1_DIR_WRITE(!INVERT_E1_DIR); } }
+    #define REV_E_DIR() { if (current_block->active_extruder == 0) { E0_DIR_WRITE(INVERT_E0_DIR); } else { E1_DIR_WRITE(INVERT_E1_DIR); } }
   #endif
 #elif ENABLED(MIXING_EXTRUDER)
   #define E_STEP_WRITE(v) NOOP /* not used for mixing extruders! */