diff --git a/packages/taro-mini-runner/src/webpack/chain.ts b/packages/taro-mini-runner/src/webpack/chain.ts
index e276f58c8536..b4852fa565d7 100644
--- a/packages/taro-mini-runner/src/webpack/chain.ts
+++ b/packages/taro-mini-runner/src/webpack/chain.ts
@@ -249,6 +249,7 @@ export const getModule = (appPath: string, {
     {
       ident: 'postcss',
       plugins: getPostcssPlugins(appPath, {
+        isQuickapp,
         designWidth,
         deviceRatio,
         postcssOption
diff --git a/packages/taro-mini-runner/src/webpack/postcss.conf.ts b/packages/taro-mini-runner/src/webpack/postcss.conf.ts
index 4f682ea90cc5..80df8f124ee0 100644
--- a/packages/taro-mini-runner/src/webpack/postcss.conf.ts
+++ b/packages/taro-mini-runner/src/webpack/postcss.conf.ts
@@ -29,6 +29,7 @@ const optionsWithDefaults = ['autoprefixer', 'pxtransform', 'cssModules', 'url']
 const plugins = [] as any[]
 
 export const getPostcssPlugins = function (appPath: string, {
+  isQuickapp = false,
   designWidth,
   deviceRatio,
   postcssOption = {} as IPostcssOption
@@ -49,7 +50,7 @@ export const getPostcssPlugins = function (appPath: string, {
     plugins.push(autoprefixer(autoprefixerOption.config))
   }
 
-  if (pxtransformOption.enable) {
+  if (pxtransformOption.enable && !isQuickapp) {
     plugins.push(pxtransform(pxtransformOption.config))
   }