diff --git a/.github/workflows/pytest-workflow.yml b/.github/workflows/pytest-workflow.yml
index 80ab8fd9b08..9d8965dc785 100644
--- a/.github/workflows/pytest-workflow.yml
+++ b/.github/workflows/pytest-workflow.yml
@@ -35,7 +35,7 @@ jobs:
       fail-fast: false
       matrix:
         tags: ["${{ fromJson(needs.changes.outputs.modules) }}"]
-        profile: ["docker", "singularity", "podman"]
+        profile: ["docker", "singularity", "conda"]
         exclude:
           - profile: "conda"
             tags: bases2fastq
@@ -121,11 +121,6 @@ jobs:
         with:
           singularity-version: 3.7.1
 
-      - name: Set up Podman
-        if: matrix.profile == 'podman'
-        run: |
-          sudo ln -sf /usr/bin/podman /usr/bin/docker
-
       - name: Set up miniconda
         if: matrix.profile == 'conda'
         uses: conda-incubator/setup-miniconda@v2
diff --git a/tests/config/nextflow.config b/tests/config/nextflow.config
index 52d96b03759..20a06c5a7ca 100644
--- a/tests/config/nextflow.config
+++ b/tests/config/nextflow.config
@@ -18,12 +18,8 @@ if ("$PROFILE" == "singularity") {
 } else if ("$PROFILE" == "mamba") {
     conda.enabled  = true
     conda.useMamba = true
-} else if ("$PROFILE" == "podman") {
-    podman.enabled  = true
-    podman.runOptions = "--runtime /usr/bin/crun --userns=keep-id --platform linux/x86_64"
 } else {
     docker.enabled = true
-    docker.fixOwnership = true
     docker.userEmulation = true
     docker.runOptions = "--platform linux/x86_64"
 }