diff --git a/examples/datasets/Dou-ucec-confirmatory.csv b/examples/datasets/Dou-ucec-confirmatory.csv new file mode 100644 index 00000000..8276f70b --- /dev/null +++ b/examples/datasets/Dou-ucec-confirmatory.csv @@ -0,0 +1,191 @@ +Idx,Case_id,Case_excluded,Batch,Plex,ReporterName,Aliquot_ID,Group,Discovery_study,Age,Sex,Histologic_Type,Histologic_grade,Tumor_size_cm,Height_at_time_of_surgery_cm,Weight_at_time_of_surgery_kg,BMI,Myometrial_invasion,Myometrial_invasion_present_specify,AJCC_tnm_cancer_staging_edition_used,Pathologic_staging_primary_tumor_pt,Pathologic_staging_regional_lymph_nodes_pn,Number_of_pelvic_lymph_nodes_examined,Tumor_stage_pathological,Race,CNV_ratio,CNV_status,POLE,MSIsensor_ratio,MSI_status,Genomic_subtype,Mutation_load,TP53,PTEN,CTNNB1,ARID1A,PIK3CA,xCell_Myeloid_dendritic_cell_activated,xCell_B_cell,xCell_T_cell_CD4+_memory,xCell_T_cell_CD4+_naive,xCell_T_cell_CD4+_(non-regulatory),xCell_T_cell_CD4+_central_memory,xCell_T_cell_CD4+_effector_memory,xCell_T_cell_CD8+_naive,xCell_T_cell_CD8+,xCell_T_cell_CD8+_central_memory,xCell_T_cell_CD8+_effector_memory,xCell_Class-switched_memory_B_cell,xCell_Common_lymphoid_progenitor,xCell_Common_myeloid_progenitor,xCell_Myeloid_dendritic_cell,xCell_Endothelial_cell,xCell_Eosinophil,xCell_Cancer_associated_fibroblast,xCell_Granulocyte-monocyte_progenitor,xCell_Hematopoietic_stem_cell,xCell_Macrophage,xCell_Macrophage_M1,xCell_Macrophage_M2,xCell_Mast_cell,xCell_B_cell_memory,xCell_Monocyte,xCell_B_cell_naive,xCell_Neutrophil,xCell_NK_cell,xCell_T_cell_NK,xCell_Plasmacytoid_dendritic_cell,xCell_B_cell_plasma,xCell_T_cell_gamma_delta,xCell_T_cell_CD4+_Th1,xCell_T_cell_CD4+_Th2,xCell_T_cell_regulatory_(Tregs),xCell_immune_score,xCell_stroma_score,xCell_microenvironment_score,Cibersort_B_cell_naive,Cibersort_B_cell_memory,Cibersort_B_cell_plasma,Cibersort_T_cell_CD8+,Cibersort_T_cell_CD4+_naive,Cibersort_T_cell_CD4+_memory_resting,Cibersort_T_cell_CD4+_memory_activated,Cibersort_T_cell_follicular_helper,Cibersort_T_cell_regulatory_(Tregs),Cibersort_T_cell_gamma_delta,Cibersort_NK_cell_resting,Cibersort_NK_cell_activated,Cibersort_Monocyte,Cibersort_Macrophage_M0,Cibersort_Macrophage_M1,Cibersort_Macrophage_M2,Cibersort_Myeloid_dendritic_cell_resting,Cibersort_Myeloid_dendritic_cell_activated,Cibersort_Mast_cell_activated,Cibersort_Mast_cell_resting,Cibersort_Eosinophil,Cibersort_Neutrophil,Mutation_signature_SBS1,Mutation_signature_SBS5,Mutation_signature_SBS6,Mutation_signature_SBS7a,Mutation_signature_SBS10a,Mutation_signature_SBS10b,Mutation_signature_SBS15,Mutation_signature_SBS20,Mutation_signature_SBS21,Mutation_signature_SBS42,Mutation_signature_SBS54,ABSOLUTE_tumor_purity,Diabetes,Metformin_treatment,Progeny_Androgen,Progeny_EGFR,Progeny_Estrogen,Progeny_Hypoxia,Progeny_JAK.STAT,Progeny_MAPK,Progeny_NFkB,Progeny_p53,Progeny_PI3K,Progeny_TGFb,Progeny_TNFa,Progeny_Trail,Progeny_VEGF,Progeny_WNT,Estimate_StromalScore,Estimate_ImmuneScore,Estimate_ESTIMATEScore,Peritoneal_ascitic_fluid,Tumor_necrosis,Margin_status,Ethnicity,Ethnicity_race_ancestry_identified,Participant_country,Tumor_site,Tumor_site_other,Tumor_focality,Number_of_pelvic_lymph_nodes_positive_for_tumor_by_ihc_staining_only,Number_of_pelvic_lymph_nodes_positive_for_tumor_by_he,Number_of_para-aortic_lymph_nodes_examined,Number_of_para-aortic_lymph_nodes_positive_for_tumor_by_ihc_staining_only,Number_of_para-aortic_lymph_nodes_positive_for_tumor_by_he,Number_of_other_lymph_nodes_examined,Number_of_other_lymph_nodes_positive_for_tumor_by_ihc_staining_only,Number_of_other_lymph_nodes_positive_for_tumor_by_he,Clinical_staging_distant_metastasis_cm,Residual_tumor,Ancillary_studies_estrogen_receptor,Ancillary_studies_progesterone_receptor,Ancillary_studies_mlh1,Ancillary_studies_msh2,Ancillary_studies_msh6,Ancillary_studies_pms2,Ancillary_studies_p53,Ancillary_studies_other_immunohistochemistry_performed,Ancillary_studies_mlh1_promoter_hypermethylation,Ancillary_studies_other_testing_performed,Donor_information_menopause_status,Donor_information_has_the_patient_ever_taken_menopausal_hormone_therapy,Donor_information_number_of_full_term_pregnancies,Ancillary_studies_other_immunohistochemistry_type_and_result,baseline_ancillary_studies_other_testing_type_and_result,History_of_cancer,Alcohol_consumption,Tobacco_smoking_history,Age_at_which_the_participant_started_smoking,Age_at_which_the_participant_stopped_smoking,On_the_days_participant_smoked_how_many_cigarettes_did_he_she_usually_smoke,Number_of_pack_years_smoked,Was_the_participant_exposed_to_secondhand_smoke,Personal_medical_history_history_source,medical_history_current_medications,Current_medications_history_source,Current_medications_medication_name_vitamins_supplements,Cancer_history_cancer_type,Cancer_history_history_source,Cancer_history_history_of_any_treatment,Cancer_history_medical_record_documentation_of_this_history_of_cancer_and_treatment,Procurement_blood_collection_minimum_required_blood_collected,Procurement_blood_collection_number_of_blood_tubes_collected,Follow-up_follow_up_period,Follow-up_is_this_patient_lost_to_follow-up,Follow-up_vital_status_at_date_of_last_contact,Follow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_last_contact,Follow-up_adjuvant_post-operative_radiation_therapy,Follow-up_adjuvant_post-operative_pharmaceutical_therapy,Follow-up_adjuvant_post-operative_immunological_therapy,Follow-up_tumor_status_at_date_of_last_contact_or_death,Follow-up_has_the_patient_ever_taken_menopausal_hormone_therapy,Follow-up_has_the_patient_ever_taken_oral_contraceptives,Follow-up_has_the_patient_ever_taken_tamoxifen,Follow-up_hypertension,Follow-up_has_the_patient_ever_been_diagnosed_with_diabetes_by_a_physician,Follow-up_number_of_full_term_pregnancies,Follow-up_has_the_patient_had_colorectal_cancer,Follow-up_measure_of_success_of_outcome_at_the_completion_of_initial_first_course_treatment,Follow-up_measure_of_success_of_outcome_at_completion_of_this_follow-up_form,Follow-up_measure_of_success_of_outcome_at_date_of_last_contact_or_death,follow-up_new_tumor_after_initial_treatment,Follow-up_type_of_new_tumor,Follow-up_site_of_new_tumor,Follow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_new_tumor_after_initial_treatment,Follow-up_additional_surgery_for_new_tumor,Follow-up_additional_treatment_radiation_therapy_for_new_tumor,Follow-up_additional_treatment_pharmaceutical_therapy_for_new_tumor,Follow-up_additional_treatment_immuno_for_new_tumor,Follow-up_days_from_date_of_collection_to_date_of_last_contact,Follow-up_cause_of_death,Follow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_death,Follow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_additional_surgery_for_new_tumor,Follow-up_procedure_type_of_new_tumor,Follow-up_residual_tumor_after_surgery_for_new_tumor +C3L-00086,C3L-00086,No,b4,16,128N,CPT0092460003,Tumor,No,56,Female,Endometrioid carcinoma,G1 Well differentiated,4,165,80,29.38,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,0,CNV_L,No,10.06,MSI-H,MSI-H,415,WT,Mutated,WT,Mutated,WT,0.164143479,1.70E-02,1.22E-02,0,2.45E-19,2.16E-18,5.14E-02,9.90E-03,2.97E-02,7.16E-02,1.61E-18,1.41E-02,1.55E-02,0,1.87E-02,0,1.91E-03,0,3.60E-19,1.40E-02,1.69E-02,1.59E-02,9.57E-03,1.20E-03,1.00E-19,0,6.63E-03,0,0,5.20E-03,6.04E-02,7.04E-03,0,5.56E-02,0.17289414,0,5.69E-02,0,5.69E-02,7.44E-03,0,6.32E-02,0.201396514,0,6.89E-02,6.41E-02,0.141278353,0,0,0,3.86E-02,0,3.80E-02,7.33E-02,0.218959886,4.88E-02,0,0,3.52E-02,8.61E-04,0,18,64,151,0,0,0,0,53,0,0,0,0.44,Yes,Yes,0.210514771,0.845332306,-7.00E-02,0.631011539,-0.659031004,1.210711348,-0.330955873,8.12E-02,-0.492262958,-0.145793715,-0.40528041,0.806494585,9.75E-02,0.428632856,4018.51975,4826.094192,8844.613942,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Both anterior and posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,1,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Current smoker: Includes daily and non-daily smokers,Unknown,NA,4,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Metformin|Lisinopril|Amlodipine|Ibuprofen|Omeprazole,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months|60 Months,No|No|No|No|No,Living|Living|Living|Living|Deceased,330|701|1046|1436|1578,No|No|No|No|Yes,No|No|No|No|Yes,No|No|No|No|No,Tumor Free|With Tumor|With Tumor|With Tumor|With Tumor,Unknown|Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown|Unknown,Yes|Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes|Yes,1|1|1|1|1,No|No|No|No|No,Not Applicable|Not Applicable|Not Applicable|Not Applicable|Not Applicable,Complete Remission|Unknown|Unknown|Persistent Disease|n/a,n/a|n/a|n/a|n/a|Persistent Disease,No|Yes|Yes|Yes|Yes,n/a|New Primary Tumor|New Primary Tumor|New Primary Tumor|New Primary Tumor,n/a|Other: Breast mets to liver and bone|Other: Breast mets to liver and bone|Other: Breast with mets to bone|Other: Breast with metastatic disease to bone,n/a|580.0|580.0|580.0|580.0,n/a|No|No|No|No,n/a|Yes|Yes|Yes|Yes,n/a|Yes|Yes|Yes|Yes,n/a|No|No|No|No,330.0|701.0|1046.0|1436.0|n/a,n/a|n/a|n/a|n/a|Breast Carcinoma,n/a|n/a|n/a|n/a|1578.0,n/a|n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a|n/a +C3L-00898,C3L-00898,No,b4,14,128C,CPT0172200008,Tumor,No,54,Female,Endometrioid carcinoma,G2 Moderately differentiated,4.6,152,88,37.88,Present,=50% myometrial invasion,Eighth Edition (2017),3b,0,5,IIIB,White,NA,NA,No,0,MSS,NA,42,WT,Mutated,Mutated,Mutated,Mutated,9.09E-02,0,4.85E-19,1.17E-17,0,7.74E-19,0,0,3.59E-03,1.15E-02,1.38E-18,0,0,0,2.04E-03,1.20E-02,0,0,0,4.06E-02,0,5.94E-03,5.27E-03,0,0,5.55E-18,2.08E-03,0,0,1.10E-17,3.96E-02,7.35E-03,0,0,3.68E-03,2.89E-02,3.75E-03,6.01E-03,9.76E-03,4.35E-02,0,4.62E-02,5.96E-02,0,0.276882335,0,0.143517668,0,0,0,7.72E-03,0.115580977,5.65E-02,8.74E-03,9.06E-02,0,4.94E-02,0,4.81E-02,4.21E-02,1.15E-02,19,21,0,0,0,0,0,0,0,0,0,NA,Yes,Yes,2.697956942,0.786356057,1.40E-02,-0.379503483,0.473007978,1.073747775,0.829383089,1.962050762,1.278534955,0.68325692,0.996951118,0.422786724,-0.45798663,1.994994225,4477.315071,5016.932324,9494.247395,Not Examined,Not identified,Margin(s) involved by invasive carcinoma,Hispanic or Latino,Mexican,Other: Mexico,Other,Endometrium,Multifocal,0,0,0,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,None,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,Metformin|Ferrous Sulfate|Flexeril|Provera,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,396|746|982|1600,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Unknown|Unknown|Unknown|Unknown,Never|Never|Never|Never,No|No|No|No,Yes|Yes|Yes|Yes,None|None|None|None,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,396.0|746.0|982.0|1600.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-00943,C3L-00943,No,b4,15,130C,CPT0086090003,Tumor,No,63,Female,Endometrioid carcinoma,G1 Well differentiated,3,163,91,34.33,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pNX,0,Stage I,White,0,CNV_L,No,0.02,MSS,CNV_L,36,WT,Mutated,Mutated,WT,WT,4.55E-02,3.88E-19,6.28E-04,1.01E-19,0,0,2.97E-04,3.35E-03,1.22E-02,2.05E-02,0,3.06E-18,2.74E-03,1.26E-03,4.46E-03,5.46E-02,5.71E-06,0.130546505,0,7.51E-02,4.50E-03,7.24E-03,2.55E-03,3.30E-03,0,2.52E-19,0,6.14E-05,0,0,3.53E-02,4.31E-03,0,1.51E-02,6.47E-02,1.28E-02,1.63E-02,9.26E-02,0.108946436,3.55E-03,0,0.109157157,3.24E-02,0,0.281253761,2.94E-02,6.24E-03,0,0,0,3.24E-02,6.70E-03,6.83E-02,2.94E-02,0.182317284,2.54E-02,2.34E-02,0.119092507,1.68E-02,0,3.41E-02,8,25,0,0,0,0,0,0,0,0,0,0.28,NA,NA,0.551969114,0.585823101,0.996080842,-0.406584048,9.15E-03,0.721380215,0.380035549,0.410550463,0.177851742,1.717087546,0.586458653,0.121059206,-1.662404381,1.319793474,5918.231281,4417.462317,10335.6936,Negative for malignancy/normal/benign,Not identified,Cannot be assessed,Not reported,Medical record does not state.,Other: Medical record does not state.,Other,Lesion occupies both anterior and posterior aspects,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,1,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Levothyroxine (TIROSINT|cloNIDine HCl (CATAPRES|hydrALAZINE (APRESOLINE,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,291|747|1093,No|No|No,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Never|Never|Never,Yes|Yes|Yes,No|No|No,1|1|1,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,237.0|693.0|1039.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-01064,C3L-01064,No,b3,9,129N,CPT0113430004,Tumor,No,54,Female,Endometrioid carcinoma,G2 Moderately differentiated,4.3,160,92,35.74,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,0,Stage I,White,0,CNV_L,No,0,MSS,CNV_L,71,WT,Mutated,Mutated,Mutated,Mutated,8.01E-02,1.50E-03,1.81E-20,0,9.80E-19,0,2.63E-02,2.27E-19,0,4.92E-03,1.19E-19,0,5.51E-03,0,3.91E-03,7.34E-03,0,3.56E-02,6.98E-19,2.07E-02,0,1.94E-03,0,1.19E-03,1.17E-18,0,1.17E-03,0,3.79E-18,2.40E-02,1.86E-02,3.53E-03,0,8.26E-02,2.97E-02,2.34E-03,4.40E-03,2.23E-02,2.67E-02,1.79E-02,0,0.101475896,5.55E-02,0,0.154581642,0,6.93E-02,4.11E-02,0,0,8.48E-02,4.02E-03,0.167085811,1.93E-02,0.144941088,1.04E-03,1.05E-02,0,6.01E-02,2.74E-02,4.09E-02,25,37,0,0,0,0,0,0,0,0,0,0.56,NA,NA,0.422129433,1.432963934,1.287031128,-0.148923826,-7.13E-02,0.298775896,1.103549818,0.560907512,-0.418490806,0.12103621,1.091016887,-0.18203253,-0.326817001,0.685441273,3950.256141,4090.849852,8041.105993,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Anterior and posterior endometrium,Unifocal,0,0,0,0,0,1,0,0,Staging Incomplete,R0: No residual tumor,Positive : 90 %,Positive : 65 %,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Normal,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Current Therapy,2,NA,NA,No,"Consumed alcohol in the past, but currently a non-drinker",Current smoker: Includes daily and non-daily smokers,24,NA,20,30,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Benadryl|Estroven|Melatonin,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,524|797|1133|1518,Yes|Yes|Yes|No,Yes|Yes|Yes|Yes,No|No|No|No,With Tumor|Tumor Free|With Tumor|With Tumor,Former Therapy|Former Therapy|Current Therapy|Former Therapy,Former Therapy|Former Therapy|Former Therapy|Former Therapy,Never|Never|Never|Never,No|No|No|No,No|No|No|No,2|2|2|3,No|No|No|No,Persistent Disease|Persistent Disease|Persistent Disease|Persistent Disease,Persistent Disease|Persistent Disease|Persistent Disease|Persistent Disease,n/a|n/a|n/a|n/a,Yes|Yes|Yes|Yes,Distant Metastasis|Distant Metastasis|Distant Metastasis|Locoregional Recurrence,Other: omentum and vaginal cuff|Other: Omentum|Lung|Other: Recurrent to endometrium,341.0|345.0|833.0|871.0,No|No|No|No,No|Yes|No|No,Yes|Yes|Yes|Yes,No|No|No|No,453.0|726.0|1062.0|1447.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-01277,C3L-01277,No,b4,13,130N,CPT0093170003,Tumor,No,61,Female,Clear cell carcinoma,G3 Poorly differentiated,3.1,152,90,38.66,Present,<50% myometrial invasion,Seventh Edition (2010),pT4 ((FIGO IVA),pN1 (FIGO IIIC1),20,Stage IV,White,27.0318891,CNV_H,No,0.63,MSS,CNV_H,79,Mutated,WT,WT,WT,WT,6.70E-02,3.20E-02,0,7.19E-20,3.43E-18,0,1.71E-19,1.37E-03,0,0,1.85E-18,4.00E-18,3.86E-03,9.83E-20,0,1.04E-02,1.89E-18,6.68E-02,8.84E-18,0.227418213,1.63E-02,1.66E-02,7.02E-03,6.29E-03,0,0,1.94E-03,0,0,2.39E-03,0,2.56E-02,0,4.36E-02,0.169763751,0,3.64E-02,4.21E-02,7.84E-02,9.01E-02,0,9.87E-03,0.107773885,0,0.102388176,0,5.12E-02,0,0,0,7.22E-02,5.25E-02,0,3.77E-02,0.335894941,0,0,0,0.108333594,3.20E-02,0,10,45,0,18,0,0,0,0,0,0,0,0.55,NA,NA,-1.058231531,-0.210626637,6.22E-02,-0.477398904,-1.192535284,0.542375786,-0.383990391,-1.006978064,0.952184605,0.798950576,-0.432900851,-0.127951891,-1.408838516,0.58655408,5240.776464,3292.003806,8532.78027,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not reported,Medical Record Does Not State,Other: Medical Record Does Not State,Other,he mass occupies the anterior and posterior aspects of the endometrial cavity,Unifocal,IHC staining not done,3,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record,Yes,Medical Record|Medical Record,Lisinopril|levothyroxine,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,380|742|996,Yes|Yes|Yes,Yes|Yes|Yes,No|No|No,Tumor Free|Tumor Free|With Tumor,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Yes|Yes|Yes,No|No|No,3|3|3,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Persistent Disease|Persistent Disease,n/a|n/a|n/a,No|Yes|Yes,n/a|Distant Metastasis|Distant Metastasis,n/a|Other: Omental lymphadenopathy|Lung,n/a|482.0|986.0,n/a|No|No,n/a|No|Yes,n/a|Yes|No,n/a|No|No,351.0|713.0|967.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-01355,C3L-01355,No,b4,16,129N,CPT0083580003,Tumor,No,55,Female,Endometrioid carcinoma,G1 Well differentiated,5,163,123,46.44,Not identified,NA,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,0.942652274,CNV_L,No,0.08,MSS,CNV_L,50,WT,Mutated,WT,Mutated,Mutated,8.62E-02,1.98E-02,1.96E-19,5.88E-19,0,0,1.91E-02,4.26E-19,0,5.35E-03,0,3.49E-03,0,1.58E-19,8.12E-03,0,3.91E-20,0,1.41E-18,5.17E-02,4.64E-02,3.94E-02,1.94E-02,4.00E-03,6.45E-19,3.77E-18,5.70E-03,6.47E-19,0,1.82E-02,1.53E-02,9.70E-03,6.38E-18,5.71E-02,4.11E-02,0,5.22E-02,0,5.22E-02,0,2.25E-02,2.93E-03,0.100605,0,0.197192035,0,0,1.23E-02,0,2.49E-02,0,1.73E-02,8.96E-02,1.77E-02,0.328690503,2.15E-02,4.21E-02,0.114054101,0,8.70E-03,0,14,32,0,0,0,0,0,0,0,0,0,0.22,NA,NA,-0.126893861,-0.984616904,0.801397286,-0.637450073,1.700052511,-1.329351105,-1.46E-02,0.472783019,0.166217987,-0.691435261,0.114622588,-0.111552549,-0.591740795,-0.469145403,3587.024284,4501.375963,8088.400247,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,Caucasian,United States,Other,Anterior and Posterior Endometrium,Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record|Self-reported and Medical Record|Medical Record|Self-reported and Medical Record|Medical Record|Medical Record,Yes,Self Report|Self Report|Self Report|Self Report|Self Report,Calcium - Vitamin D|Levothyroxine|Aspirin|Prednazole|Erythromycin,NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|Yes,Living|Living,75|75,Unknown|Unknown,Unknown|Unknown,Unknown|Unknown,Tumor Free|Tumor Free,Never|Never,Former Therapy|Former Therapy,Unknown|Unknown,No|No,No|No,2|2,No|No,Unknown|Unknown,Unknown|Unknown,n/a|n/a,Unknown|Unknown,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,75.0|75.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-01599,C3L-01599,No,b3,12,129N,CPT0087260003,Tumor,No,65,Female,Endometrioid carcinoma,G2 Moderately differentiated,2.7,147,97,44.89,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,0.156405766,CNV_L,No,0,MSS,CNV_L,112,WT,Mutated,WT,Mutated,Mutated,8.49E-02,6.91E-03,0,8.61E-20,1.59E-18,0,1.85E-02,3.54E-04,0,7.28E-03,0,1.77E-02,1.30E-02,0,4.77E-03,8.40E-03,2.16E-03,3.22E-02,0,3.16E-02,5.58E-03,5.63E-03,3.95E-03,2.83E-03,4.99E-18,3.75E-03,0,9.21E-04,1.73E-18,8.33E-03,2.50E-02,4.89E-03,6.33E-18,6.74E-02,5.44E-02,1.40E-19,1.79E-02,2.13E-02,3.92E-02,1.55E-02,0,0.114405509,0,0,0.198053445,0,5.11E-02,0,0,0,6.73E-02,1.84E-02,0,1.66E-02,0.272709018,7.14E-02,3.20E-02,0,3.93E-02,3.26E-03,9.99E-02,22,56,0,0,0,0,24,0,0,0,0,0.18,Yes,No,-2.15E-02,0.426131535,0.131651293,0.394229669,0.176353543,0.315489148,0.196728148,1.291477847,0.223097873,0.276834236,0.324712921,0.870133132,-1.74E-02,0.794763495,4440.305867,4308.379012,8748.684879,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Anterior and Posterior Endometrium,Unifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,None,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,cytotec|lipitor|lisinopril|norvasc|glucophage|alphagan|timoptic,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,343|683|1063|1434,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,None|None|None|None,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,343.0|683.0|1063.0|1434.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-01631,C3L-01631,No,b3,11,128C,CPT0091720003,Tumor,No,56,Female,Endometrioid carcinoma,G1 Well differentiated,6,160,99,38.67,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,6.78E-02,CNV_L,No,11.17,MSI-H,MSI-H,682,WT,Mutated,WT,Mutated,Mutated,0,3.09E-03,0,0,6.80E-20,8.66E-19,0,1.15E-20,5.91E-18,0,0,3.12E-03,1.13E-02,2.35E-18,0,1.01E-02,0,7.74E-03,0,4.83E-03,5.81E-04,3.74E-04,0,1.71E-04,0,9.46E-19,3.68E-03,1.87E-03,1.15E-17,1.07E-02,3.27E-02,0,0,0.119919416,0.102864575,0,3.81E-03,9.38E-03,1.32E-02,0,9.36E-03,0,0,0,0.223499106,0,1.32E-02,0,0,0,6.19E-02,0,0.33586025,0,7.82E-02,0,8.82E-02,0,0.133073003,0,5.67E-02,0,139,207,0,0,0,0,174,0,0,0,0.47,NA,NA,-0.341020298,1.20761473,-0.989413729,0.489077105,0.320796914,0.542830899,1.645872576,0.285063461,0.789691314,6.23E-02,1.703117126,-0.416434551,1.237731988,0.871017415,4219.507861,3832.887634,8052.395495,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Both Anterior and Posterior Endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,3,NA,NA,No,Alcohol consumption history not available,Current smoker: Includes daily and non-daily smokers,11,NA,30,67.5,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record,Aspirin,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Deceased,414|610|798,No|No|No,No|No|No,No|No|No,Tumor Free|Tumor Free|With Tumor,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,No|No|No,No|No|No,3|3|3,No|No|No,Not Applicable|Not Applicable|Not Applicable,Unknown|Unknown|Patient Deceased,n/a|n/a|n/a,No|No|Yes,n/a|n/a|Locoregional Recurrence,"n/a|n/a|Other: Left iliac fossa, Left sacrum, peritoneum",n/a|n/a|762.0,n/a|n/a|No,n/a|n/a|No,n/a|n/a|No,n/a|n/a|No,414.0|610.0|n/a,n/a|n/a|Other : Endometrial adenocarcinoma,n/a|n/a|798.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-01633,C3L-01633,No,b1,4,127N,CPT0091910003,Tumor,No,60,Female,Endometrioid carcinoma,G1 Well differentiated,4.5,160,143,55.86,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,0.178322095,CNV_L,No,0,MSS,CNV_L,73,WT,Mutated,WT,Mutated,WT,3.45E-02,0,0,3.39E-18,7.93E-19,1.02E-02,4.03E-02,0,3.07E-20,2.04E-02,0,7.70E-03,6.87E-03,1.99E-03,7.99E-03,3.77E-03,1.71E-02,8.06E-02,4.53E-03,4.86E-02,1.24E-03,2.28E-03,2.21E-03,5.06E-03,9.19E-20,0,9.44E-05,2.03E-19,2.26E-18,0,2.23E-02,7.18E-03,0,1.86E-02,1.47E-02,6.36E-23,2.09E-02,4.39E-02,6.48E-02,0,2.04E-02,4.91E-02,2.84E-02,0,0.352906161,0,2.18E-02,0,0,0,7.23E-02,1.62E-02,0,1.29E-02,0.240613914,4.36E-02,0,5.24E-02,0,8.46E-02,4.71E-03,25,18,22,0,0,0,0,0,0,0,0,0.21,Yes,No,0.781632785,-0.566092091,1.704101023,-0.147346941,8.50E-02,-1.034017547,-9.00E-02,0.39991664,-0.885729034,-0.166252468,8.15E-02,0.462751848,-0.929132935,4.41E-02,4592.763231,4055.100729,8647.86396,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Anterior and Posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,1,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Actos|Amitiza|Celexa|Flexeril|KlonoPIN|Lipitor|Mobic|Norco|sinemet|Tekturna HCT|Allopurionol|AsA 81mg,NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|Yes,Living|Living,327|664,No|No,No|No,No|No,Tumor Free|Tumor Free,Unknown|Unknown,Unknown|Unknown,Never|Never,Yes|Yes,Yes|Yes,1|1,No|No,Not Applicable|Not Applicable,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,327.0|664.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-01639,C3L-01639,No,b4,13,127C,CPT0091780003,Tumor,No,71,Female,Endometrioid carcinoma,G1 Well differentiated,5,160,89,34.77,Present,<50% myometrial invasion,Seventh Edition (2010),pT3a (FIGO IIIA),pNX,0,Stage III,White,1.011907283,CNV_L,No,1.13,MSS,CNV_L,456,Mutated,Mutated,WT,Mutated,Mutated,8.90E-02,3.19E-19,2.19E-19,3.06E-19,5.73E-19,2.49E-18,4.63E-18,1.15E-18,5.82E-18,6.66E-19,0,2.94E-21,1.19E-02,6.96E-19,8.84E-04,5.88E-03,0,0,0,4.97E-02,1.70E-02,1.68E-02,2.82E-03,4.89E-20,1.61E-18,1.21E-03,1.24E-03,3.09E-03,4.75E-19,1.04E-02,2.21E-02,0,0,5.86E-02,7.04E-02,9.62E-20,1.48E-02,1.01E-02,2.49E-02,0,0,6.43E-02,1.93E-02,0,0.11618684,0,8.71E-02,5.89E-03,0,0,0.104893787,0,9.17E-02,0,0.174455326,5.31E-02,6.78E-02,0,8.66E-02,3.37E-02,9.49E-02,0,27,192,0,0,0,0,85,0,0,43,0.26,NA,NA,-0.255091243,1.579198302,0.576991577,-0.190444625,0.71782467,1.115454172,1.679047346,1.269904533,-0.498095798,9.04E-02,1.954341006,-0.554553453,0.18035603,1.015914016,4196.777011,4648.744533,8845.521543,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Anterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,4 or more,NA,NA,Yes,Lifelong non-drinker,"Current reformed smoker, more than 15 years",18,21,20,3,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,sinemet|Metoprolol tartrate|Prilosec|Requip|Zoloft|Zocor|ibuprofen,Breast Cancer|Skin Cancer,Medical Record|Medical Record,Surgery|Surgery,Yes|Yes,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,342|670|1060|1427,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Yes|Yes|Yes|Yes,No|No|No|No,4 or more|4 or more|4 or more|4 or more,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,342.0|670.0|1060.0|1427.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-01664,C3L-01664,No,b2,5,127N,CPT0086490003,Tumor,No,75,Female,Endometrioid carcinoma,G2 Moderately differentiated,5.2,155,83,34.55,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,5.051972445,CNV_L,No,3.14,MSS,CNV_L,183,WT,Mutated,WT,WT,WT,7.35E-02,2.07E-02,0,0,0,7.11E-03,5.06E-02,2.54E-20,0,0,1.90E-20,2.10E-02,3.07E-02,2.76E-18,1.54E-03,3.33E-18,6.97E-03,0,3.25E-18,1.84E-03,1.42E-02,1.53E-02,4.99E-03,2.88E-03,7.48E-19,7.04E-04,0,3.61E-03,1.32E-17,2.84E-02,3.17E-02,1.88E-02,4.85E-18,5.60E-02,2.00E-02,0,3.37E-02,1.67E-18,3.37E-02,0,0,8.81E-02,9.91E-02,0,0.114647906,0,1.64E-03,2.05E-02,7.98E-02,0,0,0,0.266968512,2.71E-02,0.189947201,2.03E-02,0,0,3.27E-02,0,5.92E-02,17,50,0,0,0,0,52,26,0,0,0,0.52,NA,NA,-8.13E-02,-0.464820621,7.18E-02,1.29461329,-0.672822458,-1.092269129,0.353726316,0.281782086,-0.758120995,-1.219757543,0.613020629,0.780610055,0.434320852,-0.497425494,2086.954404,4254.848677,6341.80308,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Anterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,"Ascorbic Acid|Aspirin 81 mg|Calcium |acetaminophen |warfarin |propafenone|polyethyl glycol-prop glycol |Hydrochlorothiazide|multiple vitamin |Folic acid-Vit -B 12|Dorzolamide |Vitamin D 1,000",NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,345|655|1071|1373,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Yes|Yes|Yes|Yes,No|No|No|No,3|3|3|3,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,345.0|655.0|1071.0|1373.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-01668,C3L-01668,No,b2,5,131C,CPT0186560008,Tumor,No,37,Female,Endometrioid carcinoma,G2 Moderately differentiated,5,163,117,44.11,Not identified,NA,Eighth Edition (2017),pT1a,pN0,4,Stage IA,White,0,CNV_L,No,0.02,MSS,CNV_L,46,WT,Mutated,WT,Mutated,WT,7.12E-02,1.62E-02,4.69E-03,0,9.23E-18,2.16E-02,2.99E-02,1.30E-19,0,0,0,2.99E-02,5.24E-04,2.83E-18,9.36E-03,3.83E-03,1.93E-02,8.43E-18,0,2.74E-02,7.21E-20,0,1.96E-03,1.57E-02,2.28E-18,0,5.28E-03,7.87E-19,1.29E-17,2.05E-02,7.75E-02,7.18E-03,5.56E-18,0.115500556,2.24E-02,0,4.03E-02,1.92E-03,4.22E-02,1.21E-02,0,2.89E-02,0,0,0.297161092,0,1.12E-02,0,0,0,0.172118374,0,0.120838091,9.32E-03,0.186732225,3.75E-02,1.46E-02,7.29E-02,0,0,3.65E-02,2,24,0,0,0,0,13,0,0,0,0,0.47,Yes,Yes,-0.341556581,-0.957719768,0.284534034,-1.008999551,-0.137769316,-1.307441357,0.201843564,0.450185646,0.435963206,-0.825829562,0.210414014,1.549853643,-0.736410631,0.153118849,3716.933961,4389.747735,8106.681696,Not Examined,Not identified,Cannot be assessed,Not-Hispanic or Latino,American,United States,Other,Anterior and Posterior Endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Not applicable,R0: No residual tumor,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Former Therapy,2,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Lisinopril-HCTZ|Simvastatin|Metformin,NA,NA,NA,NA,Yes,1,12 Months,No,Living,377,No,Yes,No,Tumor Free,Never,Unknown,Never,Yes,Yes,None,No,Unknown,Complete Remission,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,377,n/a,n/a,n/a,n/a,n/a +C3L-01672,C3L-01672,No,b2,8,130C,CPT0172460008,Tumor,No,53,Female,Endometrioid carcinoma,G2 Moderately differentiated,3,163,118,44.67,Present,=50% myometrial invasion,Eighth Edition (2017),pT3a,pNX,0,IIIA,White,0.672473285,CNV_L,No,7.92,MSI-H,MSI-H,208,WT,Mutated,WT,WT,WT,1.36E-02,1.06E-02,7.97E-20,8.62E-19,1.07E-18,0,0,3.69E-19,1.60E-19,1.13E-18,3.54E-18,5.33E-19,1.43E-02,7.24E-19,1.30E-21,2.32E-03,3.52E-04,4.33E-18,0,8.50E-02,3.22E-03,1.26E-03,8.67E-03,1.17E-02,3.23E-18,5.36E-19,3.17E-03,6.05E-20,5.98E-18,2.38E-02,2.41E-02,2.09E-02,8.14E-18,3.32E-02,9.69E-02,7.38E-20,1.72E-02,1.16E-03,1.84E-02,4.84E-03,0,3.77E-02,1.03E-02,0,0.198499667,0,0,2.63E-02,0,2.11E-03,1.92E-02,2.48E-02,3.29E-03,6.71E-03,0.476896526,1.76E-02,4.10E-02,0.128732063,0,0,2.20E-03,29,32,0,0,0,19,47,23,0,0,0,0.85,Yes,Yes,-0.594531395,-0.864923509,1.451895509,0.799795961,-3.88E-02,-1.971425109,-1.824433787,-1.053802318,-0.191403293,-1.391352346,-1.807848599,-0.457897228,2.065854687,-1.625929264,1758.206873,2505.853245,4264.060118,Not Examined,Not identified,Cannot be assessed,Hispanic or Latino,Hispanic,Other: Mexico,Other,"Anterior Endomyometrium, Posterior Endomyometrium, Right and left fallopian tubes",Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,Lisinopril|Hydrochlorothiazide|Metformin|amlodipine,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,353|683|1001,Yes|Yes|Yes,Yes|Yes|Yes,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Never|Never|Never,Yes|Yes|Yes,Yes|Yes|Yes,None|None|None,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,353.0|683.0|1001.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-01729,C3L-01729,No,b4,16,128C,CPT0127610003,Tumor,No,60,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.8,157,63,25.24,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,1,Stage II,White,0.229568734,CNV_L,No,0.04,MSS,CNV_L,97,WT,Mutated,WT,Mutated,WT,0.103004948,1.01E-02,3.94E-19,0,3.84E-18,0,4.89E-02,0,3.44E-03,3.13E-02,0,8.39E-03,1.46E-02,0,1.94E-02,7.76E-03,4.85E-03,0.103948125,0,5.77E-02,1.38E-02,1.81E-02,4.05E-03,1.22E-04,3.70E-20,1.18E-03,1.58E-04,0,1.66E-17,2.09E-02,1.19E-02,6.00E-03,0,3.77E-02,2.94E-02,0,3.52E-02,6.43E-02,9.96E-02,9.32E-03,6.12E-04,6.06E-02,5.08E-02,0,0.209417137,0,6.88E-02,7.21E-03,0,0,5.88E-02,0,6.47E-02,4.66E-02,0.263941742,9.01E-02,1.63E-02,5.27E-02,0,0,0,35,28,0,0,0,0,16,0,0,0,0,0.2,NA,NA,0.797454727,-0.307133033,0.906066408,-0.687164104,1.341315968,-0.734403795,0.446060979,0.280807853,-1.876080099,6.14E-02,0.513159045,0.838131779,-0.338470453,-0.174036446,4539.089442,4978.0769,9517.166342,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not reported,Medical record does not state.,Other: Medical record does not state.,Posterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Loss of nuclear expression,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,4 or more,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,NA,Yes,NA,NA,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,400|755,Yes|Yes,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,No|No,No|No,4 or more|4 or more,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,371.0|726.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-01732,C3L-01732,No,b4,13,129C,CPT0099910003,Tumor,No,84,Female,Endometrioid carcinoma,G2 Moderately differentiated,8,160,59,23.2,Present,=50% myometrial invasion,Seventh Edition (2010),pT2 (FIGO II),pN0,9,Stage II,White,2.14E-03,CNV_L,No,19.82,MSI-H,MSI-H,676,WT,Mutated,WT,Mutated,Mutated,7.66E-02,9.83E-03,0,0,0,3.96E-18,1.01E-03,0,0,5.23E-18,0,2.29E-04,2.34E-02,8.58E-18,3.84E-03,0,1.73E-18,5.42E-18,0,8.43E-03,8.65E-03,7.39E-03,3.59E-03,6.28E-03,1.76E-19,8.33E-19,4.83E-03,3.09E-19,0,1.26E-02,2.18E-02,1.56E-02,0,6.80E-02,0.125623648,0,1.91E-02,3.10E-18,1.91E-02,0,0,3.56E-03,7.59E-02,0,0.254059786,0,8.67E-02,2.00E-02,0,2.31E-03,4.13E-02,2.90E-02,6.36E-02,6.75E-02,0.221364378,6.64E-02,0,0,6.85E-02,0,0,18,98,250,0,0,0,0,0,0,0,105,0.74,NA,NA,-0.630840503,-0.159475609,0.817061802,0.940755102,-1.499832442,0.288530733,-0.698237665,-0.239938406,0.581073052,-0.971161928,-0.77449737,-1.402800452,0.459329031,-0.423072369,2658.088029,3300.90167,5958.9897,Positive for malignancy,Present,Margins uninvolved by invasive carcinoma,Not reported,Medical Record Does Not State,Other: Medical Record Does Not State,Other,umor invades 100% of endomtrial cavity,Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,3,Cytokeratin AE1/3,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record,Yes,Medical Record|Medical Record,Simvastatin|Atenolol,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,387|743|1085,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Yes|Yes|Yes,No|No|No,3|3|3,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,366.0|722.0|1064.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-01739,C3L-01739,No,b2,5,131N,CPT0100100003,Tumor,No,71,Female,Other,G3 Poorly differentiated,3.5,165,89,32.78,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,17,Stage I,White,1.07E-02,CNV_L,No,18.91,MSI-H,MSI-H,1308,WT,Mutated,Mutated,Mutated,Mutated,0.29888615,8.24E-02,7.48E-02,0,0,9.31E-18,3.74E-02,1.00E-02,0.128787619,0.205004105,4.01E-02,2.96E-03,7.04E-03,1.10E-18,2.07E-02,2.76E-03,8.96E-18,0,6.56E-18,0,7.04E-02,5.81E-02,1.68E-02,3.07E-03,4.54E-04,0,1.70E-02,0,5.62E-18,4.75E-19,0.161381983,1.79E-02,9.09E-03,4.77E-02,0.358099116,7.87E-02,0.203546477,1.38E-03,0.20492677,1.36E-02,0,1.57E-02,0.272960521,0,2.39E-02,0.186977988,9.58E-02,0,1.03E-02,0,7.00E-02,1.25E-03,9.02E-03,0.125837008,0.13564878,6.90E-03,1.46E-04,0,3.19E-02,0,0,9,191,513,0,0,0,0,257,0,0,0,0.41,NA,NA,-0.712886693,0.99171413,-0.908704148,0.446270786,2.199885639,0.626313982,0.899018117,8.08E-02,1.798070804,-1.357002691,0.563161503,0.162628927,0.208403811,1.06936262,4058.723808,7279.442683,11338.16649,Negative for malignancy/normal/benign,Present,Margins uninvolved by invasive carcinoma,Not reported,Medical record does not state.,Other: Medical record does not state.,Other,Tumor occupies 80% of endometrial cavity,Unifocal,IHC staining not done,0,6,IHC staining not done,0,5,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,"PAX8, HNF-1 beta component, ER, PR, P53, P16, VIMENTIN, AE1/AE3; ALL POSITIVE, IHC done on endometrial biopsy",NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record,Yes,Medical Record|Medical Record,levothyroxine|Pantoprazole (Protonix),NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,412|783|1147,No|No|No,Yes|Yes|Yes,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,No|No|No,No|No|No,2|2|2,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,385.0|756.0|1120.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-01749,C3L-01749,No,b2,6,127C,CPT0127700003,Tumor,No,54,Female,Endometrioid carcinoma,G1 Well differentiated,3.5,157,76,30.54,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,2,Stage I,White,1.79E-03,CNV_L,No,0.02,MSS,CNV_L,35,WT,WT,Mutated,WT,WT,3.17E-02,0,0,3.90E-18,3.60E-19,1.11E-02,1.73E-02,5.99E-04,3.29E-03,1.59E-02,0,3.62E-18,0,0,2.85E-03,3.58E-02,0,0.212412943,1.95E-19,0.136231588,7.30E-22,8.23E-03,2.98E-05,1.31E-03,0,1.08E-19,0,1.68E-19,2.42E-18,2.61E-02,7.69E-03,0,8.64E-18,2.69E-02,1.60E-18,1.47E-02,4.97E-03,0.125751944,0.130726411,0,4.46E-03,0,5.76E-02,0,0.308827648,0,2.51E-02,5.47E-02,0,0.116206629,0,3.56E-02,4.81E-02,3.04E-02,0.160675162,3.37E-02,5.28E-03,0.119449447,0,0,0,10,22,0,0,0,0,0,0,0,0,0,0.32,NA,NA,0.648690675,0.154573407,0.594658313,-0.907043997,-0.458487295,0.280402936,-1.096688548,0.112645172,-0.720385383,1.486700506,-0.787026631,-0.436772776,-0.800584734,1.288778283,5296.512074,3618.354054,8914.866128,Negative for malignancy/normal/benign,Not identified,Cannot be assessed,Not reported,Medical Record Does Not State,Other: Medical Record Does Not State,Other,Tumor involves 50% of the anterior endometrium and 50% of the posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,NA,Yes,NA,NA,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,384|727|1177,No|No|No,No|No|No,No|No|No,Tumor Free|Tumor Free|With Tumor,Never|Never|Never,Former Therapy|Former Therapy|Former Therapy,Never|Never|Never,No|No|No,No|No|No,3|3|3,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Persistent Disease,n/a|n/a|n/a,No|No|Yes,n/a|n/a|Locoregional Recurrence,n/a|n/a|Other: retroperitoneal mass,n/a|n/a|987.0,n/a|n/a|No,n/a|n/a|No,n/a|n/a|Yes,n/a|n/a|No,361.0|704.0|1154.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-01833,C3L-01833,No,b3,11,127N,CPT0100010003,Tumor,No,62,Female,Endometrioid carcinoma,G1 Well differentiated,3.1,157,101,40.78,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,1.65E-03,CNV_L,No,0.03,MSS,CNV_L,82,WT,Mutated,Mutated,Mutated,WT,1.83E-02,0,3.12E-19,0,0,1.20E-18,5.45E-18,0,0,4.52E-03,4.44E-18,8.17E-04,1.12E-02,2.42E-03,2.89E-03,1.18E-18,1.14E-19,7.51E-18,3.07E-18,5.84E-02,0,0,1.55E-03,1.29E-02,0,0,3.07E-03,5.86E-20,0,1.67E-02,2.55E-02,1.45E-02,0,3.80E-02,9.66E-02,9.04E-03,1.05E-02,4.43E-18,1.05E-02,1.69E-02,0,0.113675626,3.73E-02,0,0.271246307,0,0,6.00E-02,0,0,2.66E-02,0,0.213022797,1.03E-02,0.219341384,2.60E-02,0,0,0,0,5.63E-03,22,38,0,17,0,0,0,0,0,0,0,0.76,Yes,No,0.454187204,-1.476122622,0.729312363,0.169100336,-0.702773155,-1.282925204,-0.471961987,-0.995322422,0.722557203,-0.623596032,-0.427346219,-2.14E-03,-0.477063936,-0.692027789,2871.523465,2857.000839,5728.524304,Negative for malignancy/normal/benign,Present,Cannot be assessed,Not reported,Medical record does not state.,Other: Medical record does not state.,Other,anterior and posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Insulin (Novolog) |Metoprolol|Pravastatin,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,421|694|1030,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Yes|Yes|Yes,Yes|Yes|Yes,3|3|3,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,376.0|649.0|985.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-01840,C3L-01840,No,b1,1,127N,CPT0091990003,Tumor,No,56,Female,Endometrioid carcinoma,G1 Well differentiated,5.5,165,103,37.83,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,7.07E-03,CNV_L,No,0.05,MSS,CNV_L,49,WT,Mutated,Mutated,Mutated,Mutated,4.54E-02,4.55E-03,2.49E-04,8.10E-19,1.53E-18,0,0,0,9.80E-21,4.24E-03,0,6.80E-19,2.54E-03,4.55E-19,0,1.25E-18,0,0,0,3.45E-03,8.19E-04,2.16E-03,2.18E-03,2.39E-03,0,1.60E-18,4.93E-03,0,9.77E-18,2.72E-02,3.71E-02,8.43E-03,0,4.31E-02,4.19E-02,3.05E-02,5.17E-03,8.18E-19,5.17E-03,6.59E-02,0,4.78E-03,0.113581244,0,6.92E-02,6.42E-03,0.180356946,0,0,0,0.139898222,1.03E-02,0.172936562,5.23E-02,9.57E-02,7.39E-02,0,0,1.25E-02,2.33E-03,0,20,25,0,0,0,0,0,0,0,0,0,0.83,Yes,No,0.118408763,3.62E-02,0.305884605,-0.45405098,-0.603255283,0.566964808,-0.127254893,0.328834416,0.374257131,-0.55463518,5.97E-02,-0.891766804,0.629323542,0.991155523,2433.141807,3410.548022,5843.689829,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Both anterior and posterior,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,1,NA,NA,No,Alcohol consumption history not available,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record,Lansoprazole|Losartan,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,348|686|1048|1442,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|With Tumor,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Yes|Yes|Yes|Yes,No|No|No|No,1|1|1|1,No|No|No|No,Not Applicable|Not Applicable|Not Applicable|Not Applicable,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Persistent Disease,No|No|No|Yes,n/a|n/a|n/a|Locoregional Recurrence,n/a|n/a|n/a|Other: Vaginal and pelvic nodes,n/a|n/a|n/a|1243.0,n/a|n/a|n/a|No,n/a|n/a|n/a|Yes,n/a|n/a|n/a|Yes,n/a|n/a|n/a|No,348.0|686.0|1048.0|1442.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-01864,C3L-01864,No,b4,13,129N,CPT0092860003,Tumor,No,80,Female,Endometrioid carcinoma,G2 Moderately differentiated,4.5,160,73,28.51,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,4.49E-03,CNV_L,No,18.93,MSI-H,MSI-H,787,WT,Mutated,WT,Mutated,Mutated,5.84E-02,1.15E-02,1.93E-03,0,2.79E-20,0,3.67E-18,0,2.42E-03,9.39E-03,1.60E-19,1.96E-04,3.45E-02,0,4.88E-20,0,0,1.47E-17,0,1.60E-20,2.25E-02,1.45E-02,8.85E-03,4.62E-03,1.07E-19,1.85E-19,1.11E-03,0,2.81E-18,1.88E-02,3.59E-02,1.52E-02,0,4.25E-02,0.256989657,0,2.74E-02,7.53E-18,2.74E-02,0,0,0.103691799,0.112177383,0,7.57E-02,0,5.04E-02,0,0,0,7.12E-02,0,3.93E-02,0.109020366,0.297022682,5.96E-03,1.20E-02,0,0.104741705,0,1.89E-02,14,99,244,0,0,0,0,135,0,0,59,0.86,NA,NA,-0.66907287,0.743923923,1.031585214,0.176813757,1.285171964,0.703753678,0.371534146,-0.605994245,0.492592676,-0.881873324,0.428918864,-0.86456841,1.141146436,-1.205182171,2613.250206,3552.002805,6165.253011,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Both anterior and posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,4 or more,NA,NA,No,Alcohol consumption history not available,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record,Cholecalciferol|Hydrochlorothiazide,NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|Yes,Living|Living,390|392,No|No,No|No,No|No,Tumor Free|Unknown Tumor Status,Unknown|Unknown,Unknown|Unknown,Unknown|Unknown,Yes|Yes,No|No,4 or more|4 or more,No|No,Not Applicable|Not Applicable,Complete Remission|Unknown,n/a|n/a,No|Unknown,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,390.0|392.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-01913,C3L-01913,No,b2,6,128C,CPT0092690003,Tumor,No,55,Female,Endometrioid carcinoma,Other: High grade,4,160,67,26.17,Present,=50% myometrial invasion,Eighth Edition (2017),pT1b,pN1,23,Stage IIIC1,White,2.70724875,CNV_L,Yes,0.17,MSS,POLE,18840,Mutated,Mutated,Mutated,Mutated,Mutated,0.117666086,1.28E-02,1.29E-02,0,3.80E-19,0,1.04E-02,1.14E-02,7.41E-03,2.46E-02,1.06E-18,2.82E-03,3.55E-02,3.07E-18,2.01E-03,2.97E-19,0,0,8.31E-19,2.21E-02,1.80E-02,1.07E-02,1.24E-02,2.29E-03,0,4.42E-18,4.79E-03,0,1.09E-17,4.91E-04,3.02E-02,3.75E-03,0,2.51E-02,0.235016335,1.13E-18,2.83E-02,1.48E-19,2.83E-02,0,2.71E-02,7.69E-03,0.125054052,0,0.198178282,0,0,2.01E-02,0,0,2.24E-02,2.24E-02,0.117390967,0.115701185,0.226384973,2.96E-02,0,7.80E-02,0,1.02E-02,0,2089,7336,0,0,4224,5063,0,0,0,0,0,0.59,NA,NA,-1.020872973,-0.703173935,-0.628478858,0.425288773,8.13E-02,-0.455588047,-0.512797008,-0.424064354,0.479794412,-0.336293525,-0.778982613,0.542219472,-0.19937804,0.399632053,3921.613839,4160.530048,8082.143888,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Both anterior and posterior,Unifocal,IHC staining not done,1,4,IHC staining not done,0,1,IHC staining not done,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,4 or more,NA,NA,No,Alcohol consumption history not available,Current smoker: Includes daily and non-daily smokers,33,NA,20,22,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,369|694|1052|1422,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Former Therapy|Former Therapy|Former Therapy|Former Therapy,Unknown|Unknown|Unknown|Unknown,No|No|No|No,No|No|No|No,4 or more|4 or more|4 or more|4 or more,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,369.0|694.0|1052.0|1422.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-01967,C3L-01967,No,b1,4,128N,CPT0108750003,Tumor,No,65,Female,Endometrioid carcinoma,G1 Well differentiated,6,164,100,37.18,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,8,Stage I,Not Reported,1.73E-02,CNV_L,No,0.02,MSS,CNV_L,165,WT,WT,WT,WT,WT,0.31592033,0,2.05E-02,2.22E-18,6.38E-19,0,0.100189533,8.00E-03,9.92E-02,0.124124935,2.89E-02,0,4.34E-03,3.56E-19,5.92E-02,6.88E-02,3.62E-03,0.345642662,6.86E-02,0.209937657,4.07E-02,3.65E-02,2.43E-02,6.77E-04,3.29E-18,3.14E-02,0,2.97E-04,3.63E-18,1.70E-03,5.10E-02,8.58E-05,0,4.22E-18,0.19494426,1.85E-21,0.156717472,0.218004461,0.374721933,1.33E-02,0,3.14E-02,0.18246362,0,0.180507056,3.69E-02,3.59E-02,0,1.88E-02,0,5.17E-02,7.32E-04,0,7.61E-02,0.241358829,1.92E-02,1.45E-02,5.57E-02,0,2.67E-02,1.48E-02,25,48,0,0,0,0,0,0,31,0,42,0.16,NA,NA,0.536843247,0.113003379,0.542891843,-0.845478311,2.148028633,-5.41E-02,0.869400448,-0.399336233,-0.451862202,2.176888745,0.825817444,1.298364714,-0.96120472,0.422316303,8031.335145,7301.581729,15332.91687,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not reported,Unknown,United States,Other,Both anterior and posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Cannot be determined,Unknown,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,4 or more,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Yes,Self Report|Self Report|Medical Record|Self Report|Self Report|Self Report|Self Report|Self Report|Self Report|Self Report,Yes,Self Report|Self Report|Self Report,Proair|Vitamins|Loratadine,NA,NA,NA,NA,Yes,1,12 Months,Yes,Living,0,Unknown,Unknown,Unknown,Unknown Tumor Status,Unknown,Unknown,Unknown,No,No,4 or more,No,Unknown,Unknown,n/a,Unknown,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a +C3L-02119,C3L-02119,No,b1,3,129N,CPT0114340003,Tumor,No,72,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.3,170,110,38.06,Not identified,NA,Seventh Edition (2010),pT1 (FIGO I),pN0,6,Stage I,White,1.516079337,CNV_L,No,0.75,MSS,CNV_L,98,WT,Mutated,WT,Mutated,Mutated,4.04E-02,8.31E-03,2.59E-19,0,5.06E-19,2.41E-03,1.88E-02,2.52E-19,0,1.39E-02,0,5.06E-03,3.35E-03,0,2.46E-02,5.93E-03,7.78E-03,3.36E-02,0,1.32E-02,3.43E-02,3.31E-02,1.59E-02,4.76E-03,0,3.87E-18,3.89E-03,0,1.63E-19,2.78E-02,2.79E-02,4.10E-03,1.60E-18,6.58E-02,1.11E-02,4.61E-03,5.32E-02,1.98E-02,7.30E-02,0,0,6.43E-03,0.152587534,0,0.208113076,0,1.33E-02,9.69E-03,0,5.39E-02,0,4.36E-02,0.105875785,1.90E-02,0.327131538,3.54E-03,1.48E-02,1.92E-02,0,2.28E-02,0,12,33,31,0,0,0,0,0,0,0,0,0.5,NA,NA,-0.476873862,-0.263096241,-0.257920119,-8.61E-02,-0.811554349,-0.685522975,0.23483925,-7.33E-02,-0.851782968,-0.444961258,0.290148182,0.963318943,0.137828906,0.568796003,3653.131273,4716.283529,8369.414802,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,Caucasian,United States,Posterior endometrium,NA,Unifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,Yes,Absent,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,None,"Napsin A, Pancytokeratin - both negative",NA,No,Alcohol consumption history not available,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record,"Atorvastatin (Lipitor)|Cholecalciferol, Vitamin D3",NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|No,Living|Living,342|567,No|No,No|No,No|No,Tumor Free|Tumor Free,Unknown|Unknown,Unknown|Unknown,Never|Never,Yes|Yes,No|No,None|None,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,323.0|548.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-02121,C3L-02121,No,b3,9,130N,CPT0114100003,Tumor,No,39,Female,Endometrioid carcinoma,G2 Moderately differentiated,4.8,175,105,34.11,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,2.17E-02,CNV_L,No,0.08,MSS,CNV_L,44,WT,Mutated,Mutated,Mutated,WT,3.86E-02,5.71E-03,9.99E-19,0,1.14E-17,0,2.38E-18,1.92E-20,0,3.01E-18,1.52E-17,5.84E-04,1.01E-02,0,0,8.46E-20,9.51E-19,0,2.21E-18,0,0,0,2.50E-03,9.63E-03,0,7.86E-18,9.76E-21,1.58E-18,8.67E-18,2.13E-02,5.75E-03,1.04E-02,0,0.152446734,0.116417636,0,1.02E-02,3.73E-19,1.02E-02,8.48E-02,0,7.33E-02,4.60E-02,0,0.235766049,0,2.99E-02,4.80E-02,0,0,0.106362312,1.67E-02,0.113006634,3.73E-02,0.163206174,3.30E-02,1.25E-02,0,0,0,0,7,16,0,0,3,3,12,0,0,0,0,0.73,NA,NA,-0.16890428,-0.399057258,0.184331649,0.162518682,-1.380936812,-1.127871458,-0.524421057,-0.456343557,0.314030403,-1.442001644,-0.483844297,-1.74904298,-3.72E-02,-0.779539053,2282.601855,2822.843276,5105.445131,Not Examined,Present,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,Caucasian,United States,Other,Both anterior and posterior,Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Premenopausal: less than 6 months since LMP AND no prior bilateral oophorectomy AND not on estrogen replacement,Never,None,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,1,12 Months|24 Months,Yes|Yes,Living|Living,417|417,No|No,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,No|No,No|No,None|None,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,170.0|170.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-02125,C3L-02125,No,b2,8,131C,CPT0197250003,Tumor,No,68,Female,Serous carcinoma,G3 Poorly differentiated,7,165,80,29.45,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,4,Stage III,White,38.83879719,CNV_H,No,1.35,MSS,CNV_H,82,Mutated,WT,WT,WT,Mutated,0.132382395,7.67E-03,2.39E-03,2.65E-19,4.45E-19,8.81E-18,7.59E-18,4.02E-03,0,0,0,0,4.50E-02,0,2.33E-03,0,1.08E-18,3.41E-03,0,1.55E-02,1.71E-02,2.23E-02,1.64E-19,4.32E-03,0,5.72E-19,1.90E-21,1.09E-19,0,2.44E-02,3.79E-02,4.40E-03,1.62E-18,0.106546166,0.228666305,0,2.09E-02,2.67E-03,2.36E-02,4.86E-02,0,7.92E-02,4.82E-02,0,2.96E-02,0,5.75E-02,0,1.64E-02,0,0.121450749,0,0.190494979,0.1760159,0.183873163,0,3.41E-02,0,8.34E-03,6.11E-03,0,14,64,0,0,0,0,0,0,0,0,0,0.47,NA,NA,-1.810015984,0.925194903,-0.19338274,0.296579574,1.628249652,1.562211057,0.741314062,-1.189854714,2.562004207,0.834973613,0.76376946,-8.92E-02,-1.247598295,0.793274634,3640.161195,3809.917664,7450.078858,Not Examined,Present,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,Caucasian,United States,Other,Both anterior and posterior,Multifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Negative,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Overexpression,Yes,Cannot be determined,Yes,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,1,PAX8 - Positive,"P16-positive, Pancytokeratin - no keratin positive metastatic cells identified, GATA-3 - negative",No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record,Yes,Medical Record|Medical Record,enalapril (VASOTEC) |traMADol (ULTRAM),NA,NA,NA,NA,Yes,1,12 Months,Yes,Living,410,Yes,Yes,No,Unknown Tumor Status,Unknown,Unknown,Unknown,Yes,No,1,No,Complete Remission,Complete Remission,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,410,n/a,n/a,n/a,n/a,n/a +C3L-02216,C3L-02216,No,b2,6,127N,CPT0104690003,Tumor,No,68,Female,Endometrioid carcinoma,G1 Well differentiated,4.5,160,87,33.98,Present,=50% myometrial invasion,Eighth Edition (2017),pT1b,pN1,18,Stage IIIC1,White,0,CNV_L,No,17.11,MSI-H,MSI-H,854,WT,Mutated,WT,Mutated,Mutated,3.15E-04,3.86E-19,6.03E-19,0,1.16E-17,7.77E-19,4.19E-04,1.61E-03,0,2.08E-19,6.58E-18,0,1.74E-02,0,4.10E-03,8.11E-03,0,0,0,2.55E-02,6.31E-03,2.78E-03,8.70E-03,2.72E-03,3.28E-18,0,2.54E-21,3.38E-19,9.06E-18,7.69E-03,1.92E-02,8.16E-03,0,9.48E-02,6.60E-02,0,8.75E-03,4.06E-03,1.28E-02,1.72E-02,0,9.74E-02,4.99E-02,0,0.206528078,0,1.86E-02,0,0,2.04E-03,4.16E-02,9.62E-03,0,1.37E-02,0.354504454,0.115254986,0,7.36E-02,0,0,0,74,345,0,0,0,0,212,0,0,0,0,0.74,NA,NA,-0.635187668,-0.45532401,0.485969702,0.81716412,-1.391959106,-0.859056651,-1.94398288,0.803064702,-0.333173048,-0.870820866,-1.828703436,-0.954724608,0.267231971,0.140468678,3182.120029,2670.093058,5852.213087,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Anterior and Posterior,Unifocal,IHC staining not done,1,4,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,None,NA,NA,Yes,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,gabapentin|ambien|plaquenil|tenormin|methotrexate|amLODIPine|AMitriptyline,Breast,Medical Record,Surgery,Yes,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,346|697|1036|1432,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Yes|Yes|Yes|Yes,No|No|No|No,None|None|None|None,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,346.0|697.0|1036.0|1432.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-02347,C3L-02347,No,b2,8,128C,CPT0113850003,Tumor,No,62,Female,Endometrioid carcinoma,G2 Moderately differentiated,4.5,165,112,41.14,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,0,CNV_L,No,9.76,MSI-H,MSI-H,331,WT,Mutated,WT,Mutated,Mutated,0.149283082,1.58E-02,1.02E-19,4.65E-20,7.30E-19,0,4.86E-02,0,2.97E-04,1.44E-02,0,5.17E-03,8.21E-03,0,9.94E-03,1.77E-03,0,6.74E-18,1.03E-18,1.28E-02,1.34E-02,1.26E-02,6.75E-03,2.85E-03,8.15E-05,0,2.29E-03,3.26E-19,1.20E-17,2.95E-02,1.72E-02,1.42E-02,0,9.94E-02,1.30E-02,3.01E-20,2.82E-02,8.85E-04,2.91E-02,3.01E-03,0,8.17E-02,7.36E-02,0,0.212249015,0,6.21E-02,2.04E-02,0,0,2.10E-02,0,0.244709493,5.31E-02,0.194216922,1.92E-02,0,0,2.03E-03,0,1.27E-02,26,61,55,0,0,0,81,0,0,0,0,0.71,Yes,No,-0.50666458,0.61431738,-2.43E-03,0.59694964,3.43E-02,0.112406606,0.345508127,-0.189280113,-0.545306974,-0.157317202,0.365770604,-8.13E-02,-0.328146903,0.424965714,3841.019296,4699.493375,8540.512671,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Both anterior and posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,3,NA,NA,No,Alcohol consumption history not available,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,"amiodarone (PACERONE)|amLODIPine (NORVASC)|aspirin | buPROPion (WELLBUTRIN SR) |carvedilol (COREG)|Cholecalciferol (VITAMIN D3)| ELIQUIS|ferrous sulfate|ferrous sulfate|gabapentin (NEURONTIN)|glipiZIDE (GLUCOTROL)|HUMULIN N & R|KLOR-CON |levothyroxine (SYNTHROID)|lovastatin (MEVACOR)|montelukast (SINGULAIR)|sertraline (ZOLOFT)|valsartan-hydrochlorothiazide (DIOVAN-HCT)",NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,323|696|1064|1438,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,3|3|3|3,No|No|No|No,Not Applicable|Not Applicable|Not Applicable|Not Applicable,Complete Remission|Complete Remission|Unknown|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,323.0|696.0|1064.0|1438.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-02353,C3L-02353,No,b4,15,129C,CPT0112780003,Tumor,No,80,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.5,155,75,31.22,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,29,Stage I,White,6.15E-03,CNV_L,No,1.89,MSS,CNV_L,257,WT,Mutated,WT,WT,WT,0.234538444,2.71E-02,1.38E-02,3.58E-18,7.67E-04,3.37E-18,0.11078579,5.46E-03,1.59E-02,5.86E-02,2.30E-19,5.35E-03,2.07E-02,0,3.31E-02,1.25E-02,8.69E-19,6.68E-03,4.42E-18,1.82E-02,6.60E-02,5.49E-02,2.56E-02,8.04E-03,3.09E-20,1.14E-02,3.49E-03,0,2.62E-19,3.64E-02,7.21E-02,2.62E-03,0,7.04E-02,0.149000429,5.15E-03,0.108182427,1.02E-02,0.118383664,0,0,2.69E-02,7.89E-02,0,0.111091904,1.39E-02,5.48E-02,2.65E-02,3.07E-02,0,5.22E-02,0,0.203734855,6.47E-02,0.27981557,2.09E-02,0,2.43E-02,0,0,1.16E-02,29,70,0,0,0,0,74,0,0,0,19,0.29,NA,NA,-0.535372076,0.600107513,3.155340654,4.16E-02,-0.12352169,-0.722810459,0.678545274,-0.4187511,-0.339408721,0.4957856,0.534735804,0.803664177,8.78E-02,-0.518905112,5771.257457,6399.411201,12170.66866,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Posterior endometrium,NA,Unifocal,IHC staining not done,0,6,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,4 or more,NA,NA,Yes,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Prilosec |aleve|Multiple vitamin|Enoxaparin sodium |Motrin,Melanoma,Medical Record,Surgery,No,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,381|564|954|1359,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Never|Never|Never|Never,No|No|No|No,No|No|No|No,4 or more|4 or more|4 or more|4 or more,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,381.0|564.0|954.0|1359.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-02354,C3L-02354,No,b3,9,127C,CPT0112910003,Tumor,No,55,Female,Endometrioid carcinoma,G1 Well differentiated,4.1,165,80,29.38,Present,=50% myometrial invasion,Seventh Edition (2010),pT3a (FIGO IIIA),pN0,9,Stage IV,White,0,CNV_L,No,0.01,MSS,CNV_L,39,WT,WT,Mutated,Mutated,WT,8.13E-02,6.42E-03,2.79E-03,0,0,0,2.68E-02,1.63E-21,2.19E-03,1.19E-02,1.28E-18,0,5.95E-03,9.25E-19,0,5.63E-18,0,1.04E-17,2.02E-18,1.47E-02,4.00E-03,9.77E-03,0,6.00E-04,0,4.65E-18,3.60E-03,3.71E-19,0,3.68E-02,5.80E-02,1.08E-02,0,4.78E-02,9.11E-03,4.96E-03,8.81E-03,8.03E-18,8.81E-03,0,0,1.01E-02,8.54E-03,0,0.38078971,0,3.62E-02,0,5.02E-02,0,4.04E-02,0,0.142753811,0.110422357,0.183556076,3.86E-03,0,3.31E-02,0,0,0,15,13,0,0,0,0,0,7,0,0,0,0.74,NA,NA,1.362300799,-0.607768574,-0.522481165,-0.79104118,0.73534036,-8.33E-02,-0.738387863,0.834938257,0.147847122,-8.77E-02,-0.492512274,-1.419153354,0.430372758,1.736080971,2798.087024,3782.760715,6580.847739,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Anterior and Posterior,Unifocal,IHC staining not done,0,4,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,R1: Microscopic residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,None,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,Medical Record,multivitamin,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,327|670|1050|1421,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,Unknown Tumor Status|Tumor Free|Tumor Free|With Tumor,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Current Therapy|Former Therapy|Former Therapy|Former Therapy,No|No|No|No,No|No|No|No,None|None|None|None,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Persistent Disease,No|No|No|Yes,n/a|n/a|n/a|Locoregional Recurrence,n/a|n/a|n/a|Other: Right pericolic gutter mass,n/a|n/a|n/a|1294.0,n/a|n/a|n/a|Yes,n/a|n/a|n/a|No,n/a|n/a|n/a|Yes,n/a|n/a|n/a|No,327.0|670.0|1050.0|1421.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|1335.0,n/a|n/a|n/a|Surgical Resection,n/a|n/a|n/a|R0: No Residual Tumor +C3L-02357,C3L-02357,No,b1,1,128N,CPT0113330003,Tumor,No,54,Female,Endometrioid carcinoma,G2 Moderately differentiated,6,157,106,43,Not identified,NA,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,White,2.510041587,CNV_L,No,0.05,MSS,CNV_L,89,WT,Mutated,WT,Mutated,Mutated,0.126444941,1.33E-02,2.30E-20,0,3.69E-18,1.09E-18,8.40E-02,0,1.06E-18,2.23E-02,0,7.06E-03,0,4.22E-19,3.25E-02,6.13E-03,9.29E-21,1.24E-02,0,2.68E-02,4.55E-02,2.51E-02,3.78E-02,3.34E-03,0,1.78E-02,2.75E-03,2.32E-03,2.85E-18,3.28E-02,2.21E-02,4.44E-03,0,5.62E-02,5.29E-18,0,7.65E-02,9.27E-03,8.58E-02,0,0,0,5.60E-02,0,0.227136013,0,3.61E-02,1.35E-02,0,0,4.91E-02,5.35E-03,0.112874235,3.22E-02,0.254988031,0.144074465,0,0,0,1.87E-02,4.99E-02,26,31,0,0,0,0,0,14,0,0,0,0.18,NA,NA,-0.124245636,9.25E-02,0.77034754,-0.48269097,4.04E-02,-1.113593164,1.02423415,0.333115793,-0.805252687,-0.400049712,1.235153615,1.039434126,0.467279941,0.500780463,4844.001649,5840.577918,10684.57957,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Anterior and Posterior,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,NA,NA,No,Lifelong non-drinker,Current smoker: Includes daily and non-daily smokers,15,NA,30,58.5,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,albuterol (PROAIR HFA)|Aspirin|Motrin|Omeprazole,NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|Yes,Living|Living,349|349,No|No,No|No,No|No,Tumor Free|Tumor Free,Unknown|Unknown,Unknown|Unknown,Never|Never,No|No,No|No,2|2,No|No,Not Applicable|Not Applicable,Complete Remission|Complete Remission,n/a|n/a,No|Unknown,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,349.0|349.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-02382,C3L-02382,No,b4,14,130C,CPT0190700008,Tumor,No,64,Female,Endometrioid carcinoma,G2 Moderately differentiated,2.5,168,107,37.93,Present,<50% myometrial invasion,Seventh Edition (2010),pT2 (FIGO II),pN1 (FIGO IIIC1),3,Stage III,White,5.17E-02,CNV_L,No,18.03,MSI-H,MSI-H,581,WT,Mutated,WT,WT,WT,7.43E-02,1.07E-02,0,0,0,0,1.53E-02,1.10E-19,2.94E-19,0,3.13E-18,1.04E-02,1.82E-02,1.63E-18,6.80E-03,3.02E-03,0,0,0,2.24E-02,1.01E-02,9.23E-03,4.74E-03,1.15E-04,3.06E-18,0,5.35E-03,2.81E-03,4.37E-18,1.72E-19,2.93E-02,1.49E-03,0,6.12E-02,2.18E-02,0,2.03E-02,1.51E-03,2.18E-02,0,0,1.37E-04,0,0,0.373585701,0,9.70E-03,0,0,5.05E-02,0,0,0.116044006,2.37E-02,0.168779456,3.61E-02,5.46E-02,0,6.21E-02,0,0.104740638,15,52,191,0,0,0,0,75,0,0,64,0.27,NA,NA,-0.159240424,1.725697304,8.39E-02,0.402260498,0.284473709,2.096147864,1.42419516,1.032923537,0.7880705,-0.262146321,1.582532969,-0.460392857,0.971265423,1.906322016,3493.014013,4634.052626,8127.066638,Negative for malignancy/normal/benign,Present,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,white,United States,Anterior endometrium,NA,Unifocal,1,0,0,0,0,0,0,0,cM0,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,Unknown,NA,NA,No,"Consumed alcohol in the past, but currently a non-drinker",Current smoker: Includes daily and non-daily smokers,25,NA,Unknown,NA,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,aspirin|atorvastatin|vitamin D3|fenofibrate micronized|ferrous sulfate|furosemide|metoprolol tartrate|pantoprazole|potassium chloride,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,360|815|1088,No|No|No,Yes|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Former Therapy|Former Therapy|Former Therapy,Never|Never|Never,Yes|Yes|Yes,No|No|No,None|None|None,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,291.0|746.0|1019.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-02384,C3L-02384,No,b2,5,127C,CPT0127980003,Tumor,No,81,Female,Serous carcinoma,G3 Poorly differentiated,2.1,163,58,21.8,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,15,Stage II,White,22.20816427,CNV_H,No,0.49,MSS,CNV_H,74,Mutated,WT,WT,WT,WT,0.150800748,5.60E-02,0,2.53E-18,0,1.15E-02,2.83E-02,9.81E-03,1.37E-02,4.02E-03,6.35E-03,0,6.74E-03,1.78E-18,4.08E-03,0,0,1.60E-02,8.14E-20,0,1.14E-02,2.08E-02,1.04E-03,4.34E-03,6.53E-03,0,2.32E-03,0,0,7.25E-03,2.19E-02,4.29E-02,0,0.138764484,7.83E-02,4.20E-18,5.97E-02,9.03E-03,6.87E-02,7.08E-02,0,0.105325826,0.155680228,0,8.38E-02,0,8.97E-02,0,6.11E-03,0,7.39E-02,0,6.47E-02,0.127723474,0.222159372,0,0,0,0,0,0,10,61,0,0,0,0,0,0,0,0,0,0.2,NA,NA,-1.173315254,0.38104993,-0.339323801,0.228006172,1.453802478,0.352534871,7.52E-02,-0.134404946,-0.872854207,0.405507519,6.20E-02,-0.230264388,-1.223733226,-0.272659945,3592.368124,4176.960813,7769.328937,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not reported,Medical record does not state.,Other: Medical record does not state.,Other,25% anterior and posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record,Yes,Medical Record|Medical Record,DULoxetine (CYMBALTA|memantine (NAMENDA XR),NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,372|725|907,No|No|No,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,No|No|No,No|No|No,2|2|2,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,326.0|679.0|861.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-02389,C3L-02389,No,b3,11,129N,CPT0203040008,Tumor,No,66,Female,Endometrioid carcinoma,G2 Moderately differentiated,5.5,155,103,42.89,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,13,Stage I,White,5.069920133,CNV_L,No,22.34,MSI-H,MSI-H,792,WT,Mutated,WT,Mutated,WT,0.115941548,2.34E-02,7.30E-21,0,4.85E-18,5.69E-18,4.25E-19,1.10E-18,0,1.29E-02,3.23E-18,9.64E-03,2.35E-02,4.70E-18,3.06E-03,1.60E-19,1.80E-19,1.00E-17,0,8.77E-03,1.71E-02,9.21E-03,8.87E-03,9.11E-03,2.27E-19,0,7.71E-03,5.70E-19,2.45E-17,2.14E-03,2.70E-02,1.56E-02,0,7.88E-03,0.236543285,1.79E-18,3.51E-02,5.10E-18,3.51E-02,0,0,0.115006357,0.105195773,0,0.12577489,1.02E-02,0.115195434,0,0,0,7.53E-02,0,5.33E-02,5.15E-02,0.263459463,0,1.53E-02,0,2.45E-02,2.40E-02,2.14E-02,22,134,155,0,0,0,137,122,0,0,0,0.84,NA,NA,-1.490880237,0.334990236,-2.305200076,1.509563344,-9.19E-03,0.718692115,0.178814955,-6.32E-02,1.24029417,-2.023194016,-1.68E-02,-0.602970907,1.296375935,-1.082169211,2125.608228,4362.302181,6487.910409,Positive for malignancy,Not identified,Margins uninvolved by invasive carcinoma,Not reported,Medical record does not state.,Other: Medical record does not state.,Anterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,None,WT1 negative,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record,Yes,Medical Record|Medical Record|Medical Record,lisinopril (PRINIVIL|hydrochlorthiazide|GLUCOSAMINE,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,412|778,No|No,Yes|Yes,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,No|No,None|None,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,351.0|717.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-02392,C3L-02392,No,b3,10,127N,CPT0203250008,Tumor,No,58,Female,Endometrioid carcinoma,G1 Well differentiated,1,173,60,19.99,Present,<50% myometrial invasion,Seventh Edition (2010),pT1 (FIGO I),pN0,14,Stage I,White,0,CNV_L,No,0,MSS,CNV_L,42,WT,Mutated,WT,Mutated,Mutated,0.119162713,1.14E-02,0,0,2.16E-18,9.70E-18,0,0,0,3.00E-02,0,1.70E-19,8.61E-03,2.45E-18,2.22E-03,3.87E-02,3.22E-19,8.67E-02,0,7.24E-02,3.67E-02,2.02E-02,2.91E-02,8.95E-04,0,0,9.67E-03,3.80E-03,8.39E-18,8.41E-19,0.115187762,1.16E-02,0,1.33E-02,1.80E-02,9.42E-19,3.67E-02,6.36E-02,0.100282353,7.92E-02,0,1.46E-02,0,0,0.297421448,0,4.48E-02,0,0,7.14E-03,0.153642558,2.55E-02,6.69E-02,0,0.150684184,0,4.15E-02,0,1.08E-02,3.77E-02,7.01E-02,16,22,0,0,0,0,0,0,0,0,0,0.42,Yes,Yes,1.158002193,0.354457106,-6.89E-02,0.904742306,-0.170557405,0.52844758,1.756731819,-0.529442237,0.698834426,0.527759844,1.922361048,-6.67E-02,-5.19E-02,0.909140434,5456.76615,6014.84868,11471.61483,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not reported,Medical record does not state.,Other: Medical record does not state.,Other,100% of anterior and 80% of posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,"Current reformed smoker, years unknown",NA,NA,Unknown,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,lisinopril (PRINIVIL|albuterol sulfate|Furosamide|Loratadine|Metformin|Megestrol,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,407|721,Yes|Yes,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,Yes|Yes,2|2,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,356.0|670.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-02399,C3L-02399,No,b1,3,127N,CPT0171090008,Tumor,No,72,Female,Endometrioid carcinoma,G1 Well differentiated,6,160,73,28.52,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,4,Stage I,White,0,CNV_L,No,18.08,MSI-H,MSI-H,658,WT,Mutated,WT,Mutated,Mutated,1.84E-02,2.46E-03,1.90E-20,0,2.85E-19,0,2.55E-18,1.83E-03,5.01E-04,2.83E-19,0,1.70E-03,1.12E-02,0,1.52E-19,6.26E-19,0,0,0,2.68E-02,2.87E-18,0,5.79E-04,9.28E-03,8.01E-19,9.24E-18,7.76E-03,0,1.80E-17,1.44E-02,1.75E-02,1.52E-02,0,3.84E-02,4.15E-02,1.65E-02,8.16E-03,3.13E-19,8.16E-03,5.11E-02,0,0.156291699,2.02E-02,0,0.133542694,0,0,7.87E-02,0,0,2.96E-02,0,6.61E-03,3.27E-03,0.321720414,0,4.93E-02,0,8.25E-02,0,6.73E-02,8,108,240,0,0,0,0,95,0,0,40,0.22,Yes,Yes,0.356523193,-1.177795445,0.955305472,1.571301844,-0.812883679,-1.144946258,-0.419224288,9.95E-02,0.795561739,-1.034651936,-0.327372214,-0.146373798,1.111735452,-0.163999141,2177.415351,2032.120904,4209.536255,Negative for malignancy/normal/benign,Not identified,Cannot be assessed,Not reported,Medical record does not state.,Other: Medical record does not state.,Other,Tumor involves the entire endometrial cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,None,NA,NA,No,Alcohol consumption history not available,Smoking history not available,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Hydrochlorothiazide |Lisinopril|Metformin (GLUCOPHAGE),NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,388|716|1121,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Yes|Yes|Yes,Yes|Yes|Yes,None|None|None,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,374.0|702.0|1107.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-02403,C3L-02403,No,b3,12,127N,CPT0203150008,Tumor,No,78,Female,Endometrioid carcinoma,G2 Moderately differentiated,2.3,152,73,31.64,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,5,Stage I,White,2.168436612,CNV_L,No,0.21,MSS,CNV_L,62,WT,Mutated,WT,WT,WT,0,1.32E-18,0,0,2.08E-18,7.23E-18,1.45E-17,5.52E-03,0,1.19E-18,6.61E-18,8.06E-04,2.42E-02,4.13E-18,0,0,0,4.37E-18,0,1.73E-02,9.67E-20,0,4.39E-03,3.72E-03,0,9.28E-19,5.83E-04,0,2.60E-17,1.04E-21,1.92E-02,8.53E-03,0,7.64E-02,0.116689455,9.92E-18,2.48E-03,2.42E-18,2.48E-03,1.09E-02,0,6.97E-02,4.28E-02,0,0.221969431,0,4.16E-02,0,0,0,8.05E-02,5.12E-02,0.186537618,4.27E-03,1.60E-02,0,2.82E-02,0,0.178831222,3.42E-02,3.33E-02,11,23,0,0,0,10,13,0,0,0,0,0.88,NA,NA,0.524381162,-0.743967618,-0.604988673,0.27303969,-2.066452686,-1.428921729,-1.047606387,0.949078836,0.584137212,-1.25762043,-0.950153209,-1.674099253,1.701743818,-1.27778508,1971.012149,1687.928722,3658.940871,Positive for malignancy,Not identified,Cannot be assessed,Not reported,Medical record does not state.,Other: Medical record does not state.,Posterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,NA,NA,No,Lifelong non-drinker,"Current reformed smoker, years unknown",NA,NA,Unknown,NA,Exposure to secondhand smoke history not available,Medical Record,Yes,Medical Record|Medical Record,carbamazepine|hydrochlorthiazide,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|Yes,Living|Living,375|375,Yes|Yes,No|No,No|No,With Tumor|With Tumor,Unknown|Unknown,Unknown|Unknown,Unknown|Unknown,No|No,No|No,Unknown|Unknown,No|No,Persistent Disease|Persistent Disease,Persistent Disease|Persistent Disease,n/a|n/a,Yes|Yes,Distant Metastasis|Distant Metastasis,Liver|Liver,325.0|325.0,No|No,No|No,No|No,No|No,344.0|344.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-02408,C3L-02408,No,b3,9,131C,CPT0111720003,Tumor,No,60,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.5,175,88,28.54,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,2,Stage I,White,3.182216519,CNV_L,No,0.02,MSS,CNV_L,43,WT,Mutated,WT,Mutated,WT,0.115998006,1.11E-02,0,3.38E-18,5.88E-18,5.47E-04,5.09E-02,2.13E-19,2.74E-18,0,0,2.50E-02,1.28E-18,0,7.00E-03,3.73E-02,4.39E-03,1.23E-02,1.07E-18,6.80E-03,5.59E-02,4.33E-02,2.60E-02,1.64E-03,0,1.37E-02,5.61E-19,3.37E-03,4.29E-18,1.55E-02,2.07E-02,3.15E-03,1.15E-18,5.09E-02,1.55E-17,6.55E-20,6.48E-02,2.51E-02,8.99E-02,0,0,2.23E-02,3.30E-02,0,6.01E-02,0,3.23E-02,3.57E-02,0,1.98E-02,0,0,0.491546368,5.58E-03,0.147737178,0,4.94E-04,0,0.116885107,0,3.46E-02,16,26,0,0,0,0,0,0,0,0,0,0.24,NA,NA,0.220732003,0.824924776,0.478561692,1.129040782,-0.51458853,-5.62E-02,1.664753554,1.113795799,-0.516980841,0.109624338,1.936502917,0.943134015,0.147189091,1.046165377,5123.511869,5729.673666,10853.18553,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Uterine Mass,Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Smoking history not available,NA,NA,NA,NA,Exposure to secondhand smoke history not available,NA,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Multivitamin|Probiotic|Aleve,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|Yes,Living|Living,442|442,No|Unknown,No|Unknown,No|Unknown,Tumor Free|Unknown Tumor Status,Never|Unknown,Former Therapy|Former Therapy,Never|Unknown,No|No,No|No,2|2,No|No,Complete Remission|Unknown,Complete Remission|Unknown,n/a|n/a,No|Unknown,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,424.0|424.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-02409,C3L-02409,No,b3,9,128C,CPT0111810003,Tumor,No,60,Female,Endometrioid carcinoma,G1 Well differentiated,2,160,98,38.16,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,5,Stage I,White,8.62E-04,CNV_L,No,4.9,MSS,CNV_L,213,WT,WT,Mutated,Mutated,Mutated,0.127920425,1.90E-02,2.77E-20,0,1.96E-18,0,3.77E-02,2.43E-19,8.74E-19,1.18E-04,2.90E-18,3.50E-03,0,0,6.78E-03,0,0,0,8.79E-18,0,4.10E-03,1.61E-02,1.10E-03,4.66E-04,5.72E-19,4.44E-18,6.24E-03,8.34E-19,1.75E-19,2.03E-02,3.67E-02,1.07E-02,3.92E-19,6.64E-02,1.51E-02,2.65E-02,2.02E-02,0,2.02E-02,1.77E-02,0,0.100500717,0.108031029,0,0.290292754,0,6.15E-02,0,1.58E-02,2.14E-02,1.09E-02,0,2.18E-02,3.83E-02,0.24271605,4.37E-02,2.15E-02,0,1.96E-03,3.86E-03,0,42,21,0,0,0,0,45,0,0,38,18,0.69,NA,NA,1.765120506,0.564339941,-2.352111854,0.254354244,0.560087239,0.560796752,0.372782855,0.63330904,0.983472617,-0.158391359,0.502633446,-0.28393349,0.774743392,1.097352889,3326.749174,4805.566666,8132.315839,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Uterine mass,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,Unknown,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Former Therapy,2,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Adderall|Dexilant|Tribenzor|Albuterol inhaler|Megestrol Acetate|Potassium Chloride|Melatonin|Multivitamin|Vitamin D3,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|Yes,Living|Living,427|427,No|No,No|No,No|No,Tumor Free|Tumor Free,Former Therapy|Former Therapy,Former Therapy|Former Therapy,Never|Never,Yes|Yes,No|No,2|2,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|Unknown,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,404.0|404.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-02411,C3L-02411,No,b3,10,129C,CPT0111880003,Tumor,No,81,Female,Endometrioid carcinoma,G2 Moderately differentiated,6,155,76,31.63,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,2,Stage I,White,1.741142725,CNV_L,No,30.57,MSI-H,MSI-H,1387,Mutated,Mutated,WT,Mutated,Mutated,7.38E-02,1.21E-19,0,9.55E-18,1.84E-18,5.97E-18,5.85E-18,0,6.16E-18,1.31E-17,0,0,9.82E-03,0,2.43E-19,3.77E-20,0,0,3.70E-18,5.08E-19,7.20E-03,9.83E-03,0,0,0,0,7.70E-04,3.01E-20,3.76E-18,6.26E-02,3.54E-03,1.17E-02,0,0.103303567,9.27E-03,0,4.80E-03,4.59E-03,9.39E-03,0,8.64E-03,1.43E-02,0,0,0.102083916,0,3.92E-02,1.50E-02,0,1.03E-02,0,0,0.346403092,3.29E-03,8.49E-02,0,2.48E-02,0,0.297429038,1.41E-02,3.96E-02,0,93,340,0,0,0,201,231,0,0,143,0.72,NA,NA,-0.653334298,1.426061946,0.606151999,2.487905238,-0.677717126,1.085715164,1.932674343,6.49E-02,-0.154000378,-0.773704446,2.079873501,-1.686194991,1.788934529,0.352786302,2763.797411,3784.427922,6548.225333,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,Caucasian,United States,Other,Uterine Mass,Unifocal,0,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Present,Unknown,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,"Current reformed smoker, more than 15 years",25,28,10,1.5,Exposure to secondhand smoke history not available,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Aleve|Altrace|AmLODIPine Besylate|Calcium|Famotidine|Multivitamin|Ocuvite|Aspirin|Simvastatin,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|Yes,Living|Living,385|784,Yes|Yes,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,No|No,2|2,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,367.0|766.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-02412,C3L-02412,No,b1,1,131C,CPT0111950003,Tumor,No,74,Female,Endometrioid carcinoma,G1 Well differentiated,5,152,83,35.79,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,2,Stage I,White,5.18E-02,CNV_L,No,0.15,MSS,CNV_L,78,WT,Mutated,Mutated,Mutated,WT,8.56E-02,5.91E-03,1.67E-20,0,1.12E-17,1.30E-19,1.30E-02,3.82E-18,1.43E-17,3.94E-20,2.98E-18,1.86E-02,4.17E-03,0,1.41E-03,0,2.51E-19,0,4.03E-18,5.05E-03,8.83E-03,9.60E-03,1.47E-02,5.35E-03,1.17E-18,0,3.84E-04,0,2.23E-17,6.85E-03,6.49E-03,5.27E-03,0,9.88E-02,2.14E-02,1.38E-18,1.43E-02,0,1.43E-02,7.27E-03,0,9.77E-03,4.65E-02,0,0.184902803,0,0,5.69E-02,0,8.53E-02,0,4.09E-02,0,1.18E-02,0.422752469,2.58E-03,1.21E-02,6.33E-02,0,5.61E-02,0,28,30,0,0,0,11,0,0,0,0,0,0.55,NA,NA,0.925530522,-0.646528744,-0.176359011,-0.721992448,-8.11E-02,-1.302851061,-0.353073928,8.29E-02,-1.037386416,-1.766782648,-0.351390319,-0.29183766,0.855230241,-0.616219991,2140.034868,3257.757281,5397.792149,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Uterine Mass,Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,Unknown,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Former Therapy,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Levothyroxine|Lovastatin|Oxybutynin|Aspirin|Calcium + Vitamin D|Multivitamin|Fish Oil|PreserVision,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,354|656|1110,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Former Therapy|Former Therapy|Former Therapy,Former Therapy|Former Therapy|Former Therapy,Unknown|Unknown|Unknown,No|No|No,No|No|No,3|3|3,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,329.0|631.0|1085.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-02449,C3L-02449,No,b3,10,128N,CPT0186720008,Tumor,No,58,Female,Clear cell carcinoma,G3 Poorly differentiated,3.5,163,62,23.34,Present,<50% myometrial invasion,Eighth Edition (2017),pT1a,0,4,IA,Black or African American,NA,NA,Yes,0.04,MSS,POLE,4971,WT,WT,WT,Mutated,Mutated,0.280735109,0.115934873,5.15E-02,2.57E-18,0,1.75E-18,8.87E-02,1.11E-02,0.11887045,0.156832999,0.103774282,3.03E-02,5.12E-02,1.16E-18,7.26E-03,3.12E-03,1.33E-18,0,1.77E-18,1.08E-02,0.121097158,9.21E-02,3.79E-02,5.86E-03,1.65E-03,1.02E-02,2.41E-02,0,1.99E-02,1.98E-02,0.177433185,1.96E-02,6.61E-03,0.159505408,0.253316382,9.39E-03,0.266106727,1.56E-03,0.267667084,2.39E-03,8.38E-03,9.61E-03,0.218345012,0,2.69E-02,4.38E-02,7.79E-02,0,1.08E-02,0,0.192756947,1.64E-02,3.33E-03,0.16084529,0.173853302,3.27E-03,0,4.70E-02,0,0,4.60E-03,189,215,0,0,2288,2259,0,0,0,0,0,NA,NA,NA,-2.504332116,1.04349973,-3.389075924,-0.733873847,2.907446761,2.018156641,1.137366865,-0.153284942,0.560531879,-1.060715759,0.572501364,6.18E-02,1.977527161,-1.708321409,4232.613174,7850.345549,12082.95872,Not Examined,Not identified,Cannot be assessed,Not-Hispanic or Latino,African American,United States,Other,Posterior Endomyometrium,Unifocal,0,0,3,0,0,0,0,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Absent,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record,Yes,Medical Record,Lisinopril,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,461|787|1018|1452,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Never|Never|Never|Never,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,None|None|None|None,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,461.0|787.0|1018.0|1452.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-02468,C3L-02468,No,b2,5,130C,CPT0126000003,Tumor,No,63,Female,Endometrioid carcinoma,G1 Well differentiated,6,157,86,34.82,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,11,Stage I,White,0.110322572,CNV_L,No,0.16,MSS,CNV_L,168,WT,Mutated,WT,WT,WT,7.20E-02,0,0,0,4.46E-18,0,0,6.74E-05,1.32E-02,2.66E-02,0,1.08E-17,2.01E-03,0,4.26E-03,6.64E-02,0,0.303144277,0,0.186393915,8.02E-03,1.40E-02,1.01E-02,0,0,5.01E-18,0,3.44E-19,0,0,1.67E-02,0,0,4.75E-02,0,8.14E-03,1.70E-02,0.191923089,0.208916654,8.43E-02,0,7.23E-02,0.101415408,0,0.265756628,0,2.48E-02,0,0,0,7.62E-02,0,2.49E-02,1.02E-02,0.154901341,7.57E-03,1.81E-02,0.159486207,0,0,0,6,33,53,0,0,0,45,0,0,0,0,0.34,Yes,No,2.530011759,-1.573755029,-0.427557694,-1.155008403,0.163870676,-1.891298456,-0.548637648,-0.659051556,-0.620247876,0.966082411,-0.420254571,0.240475841,-4.85E-02,-0.45084239,5934.88564,4821.034666,10755.92031,Not Examined,Present,Margins uninvolved by invasive carcinoma,Hispanic or Latino,Caucasian,United States,Other,Anterior and Posterior Endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Smoking history not available,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,1,12 Months,Yes,Living,1,Unknown,Unknown,Unknown,Unknown Tumor Status,Unknown,Unknown,Unknown,No,Yes,Unknown,Unknown,Unknown,Unknown,n/a,Unknown,n/a,n/a,n/a,n/a,n/a,n/a,n/a,1,n/a,n/a,n/a,n/a,n/a +C3L-02545,C3L-02545,No,b3,10,127C,CPT0113060003,Tumor,No,55,Female,Endometrioid carcinoma,G1 Well differentiated,20,175,134,43.76,Present,=50% myometrial invasion,Seventh Edition (2010),pT3a (FIGO IIIA),pN2 (FIGO IIIC2),9,Stage III,White,1.309762883,CNV_L,No,0.18,MSS,CNV_L,50,WT,WT,Mutated,Mutated,Mutated,0,2.42E-18,1.21E-18,4.27E-18,2.16E-18,0,1.11E-17,0,2.33E-18,1.26E-17,0,0,2.42E-02,0,0,2.21E-03,0,3.57E-17,0,8.88E-03,0,0,3.83E-04,1.46E-03,0,1.09E-17,2.00E-03,1.38E-18,3.59E-19,0,1.25E-18,6.04E-03,1.24E-17,3.17E-02,1.80E-18,0,9.74E-04,1.10E-03,2.08E-03,0.13244133,0,6.20E-02,0,0,0.276946099,0,7.19E-02,0,0,0,5.66E-02,5.73E-02,2.87E-02,0,0.106734243,0,7.98E-02,0,6.13E-02,5.94E-02,6.89E-03,14,34,0,0,0,0,0,0,0,0,0,0.62,Yes,No,-1.035116488,1.384020416,-1.590689016,1.422513221,-0.974504776,1.021570706,-1.223645756,0.505641544,-0.471251062,-1.733072855,-0.97792523,-1.808847395,1.594489641,1.278755187,1096.432541,1618.092058,2714.524599,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Anterior and Posterior,Unifocal,IHC staining not done,3,4,IHC staining not done,3,13,IHC staining not done,6,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,None,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Current smoker: Includes daily and non-daily smokers,25,NA,10,15,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,"Advair Diskus|Lasix |Lisinopril|Zyrtec|Actos|Tylenol extra strength|MetroCream topical cream|Nystatin cream |ProAir HFA|Lipitor|CeleBREX 200 mg| Motrin IB 200 mg|Prevacid 30mg|Zofran 4 mg|Protonix 40 mg |triamcinolone 0.1% Cream|Tylenol 8 Hour 650 mg oral tablet,|Glucophage 850 mg oral tablet",NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,356|686|1069|1432,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Never|Never|Never|Never,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,None|None|None|None,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,356.0|686.0|1069.0|1432.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-02555,C3L-02555,No,b1,2,127N,CPT0128370003,Tumor,No,71,Female,Endometrioid carcinoma,G1 Well differentiated,4,157,137,55.3,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pNX,0,Stage I,White,0.321691537,CNV_L,No,0,MSS,CNV_L,29,WT,Mutated,WT,Mutated,WT,9.10E-02,0,2.35E-19,0,0,0,5.19E-03,0,1.55E-19,1.02E-02,7.07E-19,0,7.04E-03,2.15E-03,1.09E-02,2.79E-02,2.20E-03,0.221278411,0,0.10293007,8.28E-03,1.23E-02,2.62E-03,6.99E-03,0,4.16E-03,0,2.87E-03,0,4.10E-03,1.28E-02,0,0,3.13E-02,2.97E-02,0,2.36E-02,0.138481455,0.162087047,0,1.31E-02,4.17E-02,6.22E-03,0,0.271539543,0,1.98E-02,3.24E-03,0,0,7.06E-02,0,6.78E-02,3.06E-02,0.214448819,2.77E-02,4.10E-02,0.109887591,0,0,8.23E-02,6,8,0,0,0,0,0,0,0,11,0,0.28,NA,NA,0.730573088,0.2194551,0.904615117,-0.773859855,0.600982588,-0.336610101,0.877717236,0.776917366,-0.742086405,0.909248452,0.986073372,0.732167066,-0.910661952,0.548064114,5856.975157,4881.545196,10738.52035,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Both anterior and posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,None,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Aspirin|Cozaar|Toprol-XL,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Deceased,323|685|1059|1421,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Yes|Yes|Yes|Yes,No|No|No|No,None|None|None|None,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,323.0|685.0|1059.0|n/a,n/a|n/a|n/a|Other : Acute Respiratory Failure,n/a|n/a|n/a|1421.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-02557,C3L-02557,No,b3,12,130N,CPT0128610003,Tumor,No,60,Female,Endometrioid carcinoma,G3 Poorly differentiated,3.5,173,62,20.69,Not identified,NA,Seventh Edition (2010),pT1a (FIGO IA),pN0,0,Stage I,White,22.0323639,CNV_H,Yes,0.28,MSS,POLE,10579,Mutated,Mutated,Mutated,Mutated,Mutated,0.220211953,5.10E-02,1.69E-02,5.55E-19,6.69E-04,1.24E-18,1.21E-02,1.31E-02,8.83E-03,3.60E-02,8.54E-03,1.50E-02,1.25E-02,3.11E-18,1.05E-02,8.92E-20,3.37E-18,5.82E-18,7.98E-19,0,7.25E-02,5.25E-02,2.65E-02,2.73E-03,0,0,1.17E-03,0,1.21E-18,2.28E-02,9.78E-02,3.28E-02,0,0.111273874,0.382940999,1.22E-02,9.75E-02,2.95E-18,9.75E-02,1.76E-02,0,7.00E-02,0.15254295,0,6.31E-02,5.22E-02,9.29E-02,0,5.22E-03,0,0.104300943,0,4.25E-02,0.116217161,0.28169176,0,0,0,0,0,1.74E-03,499,638,0,0,5226,4189,0,0,0,0,0,0.26,Yes,Yes,-1.423493372,-0.150835025,-0.981849085,1.746109297,1.274855061,0.46070137,-1.254264295,-1.456454739,0.255014024,-1.441478311,-1.543809731,-1.0709663,0.808796046,-3.59E-02,2769.3066,5475.036872,8244.343472,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Both anterior and posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,8,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,Yes,Cannot be determined,Yes,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,3,p16 & p53: Neoplastic cells demonstrate patchy positivity,Pancytokeratin stain: no tumor cells are identified,No,Alcohol consumption history not available,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,Aspirin|Ferrous sulfate|Metformin|Novolin N Relion,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,335|654|1042|1375,No|No|No|No,No|No|No|No,No|No|No|No,Unknown Tumor Status|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,3|3|3|3,No|No|No|No,Not Applicable|Not Applicable|Not Applicable|Not Applicable,Unknown|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,335.0|654.0|1042.0|1375.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-02602,C3L-02602,No,b3,12,127C,CPT0113910003,Tumor,No,57,Female,Endometrioid carcinoma,G3 Poorly differentiated,4.2,173,101,33.75,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,4,Stage I,White,1.32E-03,CNV_L,No,26.59,MSI-H,MSI-H,832,WT,WT,WT,Mutated,Mutated,3.34E-19,5.10E-04,3.76E-19,0,6.26E-19,0,0,4.44E-19,3.62E-19,4.89E-20,3.03E-18,4.75E-03,5.87E-03,0,4.90E-20,1.19E-02,0,6.60E-18,0,2.55E-02,3.24E-04,3.85E-20,7.84E-03,5.28E-03,7.01E-18,0,0,2.38E-20,5.72E-19,3.21E-02,2.44E-03,1.07E-02,1.56E-17,9.92E-02,0.152285652,0,4.07E-03,5.96E-03,1.00E-02,0,0,7.02E-02,1.38E-02,0,0.110649004,0,9.53E-02,0,0,0,0.133048471,4.63E-03,4.78E-02,0,0.333095274,0,8.90E-02,9.45E-02,0,8.02E-03,0,0,111,351,0,0,0,0,76,0,0,67,0.57,NA,NA,-1.087374265,0.396265585,-0.37634493,-0.991307533,-0.927092155,-0.242996616,-1.262112281,0.66364367,-1.543802576,-1.215483159,-1.233692111,-1.935854835,0.824210479,-1.660052003,1652.649136,1906.465199,3559.114335,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Anterior and Posterior,Unifocal,IHC staining not done,4,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,R0: No residual tumor,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record,Yes,Medical Record,Vitamin D 2000,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,329|692|1010|1431,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Never|Never|Never|Never,No|No|No|No,No|No|No|No,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,329.0|692.0|1010.0|1431.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3L-02741,C3L-02741,No,b1,2,128N,CPT0188190004,Tumor,No,59,Female,Endometrioid carcinoma,G1 Well differentiated,4.2,155,109,45.34,Present,<50% myometrial invasion,Eighth Edition (2017),pT1a [IA],pN0,3,pT1a [IA],White,0,CNV_L,No,0.01,MSS,CNV_L,78,WT,Mutated,Mutated,Mutated,Mutated,0.126942286,2.15E-02,1.71E-02,0,0,2.07E-18,3.35E-02,3.02E-03,2.14E-02,6.28E-02,0,6.40E-03,7.92E-03,1.60E-19,5.97E-03,0,7.52E-04,6.65E-18,6.97E-19,9.47E-03,3.51E-02,2.66E-02,1.44E-02,2.66E-03,0,1.50E-18,6.43E-03,9.63E-21,0,0,6.27E-02,7.23E-03,0,3.31E-02,0.100821553,1.10E-02,5.82E-02,3.32E-18,5.82E-02,2.68E-02,0,3.61E-02,5.27E-02,0,0.280410779,1.16E-02,5.20E-02,0,2.63E-02,0,4.09E-02,0,4.53E-02,8.59E-02,0.201740993,5.55E-02,0,0,0,3.42E-02,5.05E-02,17,32,21,0,0,0,0,0,0,0,0,0.46,Yes,Yes,0.394003455,-0.260573858,0.954144865,-0.1668009,0.595689226,0.273563673,0.532828325,0.731187029,0.373708248,-0.416185648,0.578089144,0.159976594,-0.218940957,1.024427815,4333.180519,5202.11138,9535.291899,Not Examined,Present,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Endometrium,Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,1,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Lantus|Metformin|Allopurinol|Simvastatin|Metoprolol|Vitamin D,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,414|750,No|No,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Former Therapy|Former Therapy,Never|Never,Yes|Yes,Yes|Yes,1|1,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,371.0|707.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-02744,C3L-02744,No,b2,6,128N,CPT0188370003,Tumor,No,73,Female,Serous carcinoma,G3 Poorly differentiated,3.2,157,82,32.92,Present,<50% myometrial invasion,Eighth Edition (2017),pT1a [IA],pN0,2,pT1aN0,White,13.89818603,CNV_H,No,0.64,MSS,CNV_H,72,Mutated,Mutated,WT,WT,WT,0.138868154,3.44E-02,3.30E-03,0,3.52E-19,6.03E-03,0,5.85E-19,3.31E-03,1.25E-03,4.72E-18,0,6.03E-03,0,3.64E-03,8.74E-19,5.07E-20,2.35E-19,0,0,1.59E-02,2.95E-02,1.56E-03,9.53E-03,2.97E-03,0,1.09E-02,0,0,4.19E-02,3.62E-02,1.53E-02,8.20E-18,4.62E-02,9.80E-02,7.17E-03,4.45E-02,5.54E-19,4.45E-02,0,0,2.77E-02,0.116519696,0,0.135637399,0,0.127290393,0,0,0,5.12E-02,6.19E-03,8.33E-02,0.138718106,0.272059461,0,1.69E-02,0,2.19E-02,2.63E-03,0,17,52,0,0,0,0,0,0,0,0,0,0.81,NA,NA,-0.591102835,-0.607538601,-1.592816372,-0.269396188,1.790264105,3.63E-02,-0.305010908,-0.603350865,0.753250993,-1.048370597,-0.641485937,-0.90309894,-0.150361494,7.96E-02,2676.453008,3594.013095,6270.466102,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,Caucasian,Other: Unknown,Other,Endometrium,Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Positive : 10 %,Negative,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Overexpression,Yes,Cannot be determined,Yes,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,4 or more,p16 - Overexpression,Ki-67 - 80%,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Lisinopril|Hydrochlorothiazide|Lovastatin,NA,NA,NA,NA,Yes,2,12 Months,Yes,Living,455,No,Yes,No,Unknown Tumor Status,Never,Former Therapy,Never,Yes,No,4 or more,No,Unknown,Unknown,n/a,Unknown,n/a,n/a,n/a,n/a,n/a,n/a,n/a,407,n/a,n/a,n/a,n/a,n/a +C3L-02746,C3L-02746,No,b2,6,130N,CPT0188270004,Tumor,No,66,Female,Endometrioid carcinoma,G2 Moderately differentiated,2.8,160,98,38.26,Present,=50% myometrial invasion,Eighth Edition (2017),pT1b,pN0,2,Stage IB,White,5.79E-03,CNV_L,No,0.15,MSS,CNV_L,66,WT,Mutated,WT,WT,WT,6.95E-02,1.26E-02,6.15E-20,0,0,2.10E-18,0,0,2.16E-19,7.09E-03,0,5.92E-03,7.51E-03,4.94E-19,3.67E-04,2.48E-19,0,1.60E-18,0,3.99E-02,8.80E-03,5.85E-03,1.19E-02,1.07E-03,0,0,7.08E-03,0,1.74E-18,5.57E-18,9.68E-03,8.33E-03,0,9.51E-03,9.31E-02,8.07E-03,1.52E-02,9.23E-19,1.52E-02,1.92E-02,0,0.124264868,7.12E-02,0,0.157472456,0,8.32E-02,0,0,0,3.95E-02,1.20E-02,2.82E-02,0,0.278203367,0,7.26E-02,0,4.20E-02,2.23E-02,4.98E-02,22,38,0,0,0,0,0,0,0,0,0,0.52,Yes,Yes,0.728367234,1.16830713,1.152749632,-0.407007597,0.657242715,0.899014175,5.75E-02,1.238954416,0.607780177,-0.486863626,9.67E-02,-0.535969293,-0.328143904,6.61E-02,3458.857808,3687.508458,7146.366266,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Endometrium,Unifocal,0,0,1,0,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self Report|Self Report|Self Report,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Alpha Lipoic Acid|Aspirin |Calcium|Cinnamon|Cranberry|Januvia|Metformin|Vitamin B-12|Vitamin C|Vitamin E,NA,NA,NA,NA,Yes,2,12 Months,Yes,Living,313,Yes,No,No,Unknown Tumor Status,Never,Never,Never,Yes,No,2,No,Unknown,Unknown,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,288,n/a,n/a,n/a,n/a,n/a +C3L-02747,C3L-02747,No,b2,6,129N,CPT0188480004,Tumor,No,66,Female,Endometrioid carcinoma,G2 Moderately differentiated,0,160,74,28.85,Present,<50% myometrial invasion,Eighth Edition (2017),pT1a [IA],pN0,2,Stage IA,White,0.16469716,CNV_L,No,0.02,MSS,CNV_L,79,Mutated,Mutated,Mutated,WT,WT,4.12E-02,1.05E-22,8.70E-04,4.52E-18,0,4.80E-18,2.41E-02,9.86E-03,5.64E-02,7.24E-02,0,0,1.75E-02,4.40E-18,4.51E-03,8.37E-03,1.84E-18,0.132000137,0,4.81E-02,0,1.00E-03,9.73E-04,2.88E-03,1.71E-18,0,2.58E-03,0,4.18E-19,0,3.99E-02,7.99E-03,1.47E-18,0,0.122991193,1.71E-03,4.25E-02,7.17E-02,0.114212713,6.42E-02,0,9.01E-02,5.63E-02,0,0.241969113,0,8.69E-02,0,9.07E-02,0,2.89E-02,0,5.58E-02,3.88E-02,0.15366573,2.64E-04,5.30E-02,1.25E-02,0,1.59E-02,1.09E-02,16,37,0,0,0,0,18,0,0,0,0,0.23,NA,NA,0.556301124,-3.46E-02,2.356294556,-0.900618903,0.195743885,7.99E-02,-7.87E-02,0.506302618,-0.775327931,0.533758841,-0.189949983,-0.638969563,-1.566650249,0.740481676,4853.985643,4050.826376,8904.812019,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Endometrium,Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Current Therapy,None,NA,NA,Yes,Lifelong non-drinker,"Current reformed smoker, more than 15 years",19,28,5,2.3,Exposure to secondhand smoke history not available,Self-reported and Medical Record,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Progesterone |Thyroid TABS|Vitamin D,Basal Cell Cancer,Self-reported and Medical Record,Other(Mohs treatment),Yes,Yes,2,12 Months,Yes,Living,355,No,No,No,Tumor Free,Former Therapy,Never,Never,No,No,None,No,Complete Remission,Complete Remission,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,321,n/a,n/a,n/a,n/a,n/a +C3L-02800,C3L-02800,No,b3,11,129C,CPT0186900008,Tumor,No,62,Female,Endometrioid carcinoma,G2 Moderately differentiated,8,160,44,17.36,Present,=50% myometrial invasion,Eighth Edition (2017),1b,1,7,IIIC1,Not Reported,0,CNV_L,No,0.04,MSS,CNV_L,77,WT,Mutated,WT,Mutated,WT,0.13088719,5.54E-02,2.39E-20,0,3.10E-18,5.36E-18,2.03E-02,5.60E-19,5.80E-19,1.30E-02,1.86E-18,3.28E-03,0,4.58E-19,4.00E-03,0,2.91E-03,0,0,2.51E-02,9.02E-02,5.21E-02,4.67E-02,8.00E-03,4.24E-03,3.04E-02,1.26E-02,4.66E-03,1.83E-18,0,3.64E-02,1.13E-02,0,2.48E-02,0,6.41E-03,0.130438247,2.67E-19,0.130438247,0,4.00E-02,6.39E-02,3.20E-02,0,0.191386648,0,2.59E-05,0,0,2.46E-03,7.08E-02,2.80E-02,0,0,0.393414602,0,4.46E-02,9.10E-03,0,4.87E-03,0.119450398,34,35,0,0,0,0,0,0,0,0,0,0.34,NA,NA,0.916979191,0.328143467,-0.133290382,1.07839776,0.800271123,-0.184025007,1.53154745,2.035646258,0.126621444,-0.617025882,1.690917707,1.075984327,0.427187422,0.207440286,4542.005739,5923.57068,10465.57642,Not Examined,Not identified,Cannot be assessed,Not reported,Patient did not disclose,Other: Patient did not disclose,Other,"anterior and posterior endomyometrium, lower uterine segment",Unifocal,3,0,0,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Absent,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,4 or more,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Coumadin|Toprol XL|Lasix,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,333|782|1099,Yes|Yes|Yes,Yes|Yes|Yes,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Never|Never|Never,Yes|Yes|Yes,No|No|No,4 or more|4 or more|4 or more,No|No|No,Unknown|Unknown|Unknown,Complete Remission|n/a|n/a,n/a|Complete Remission|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,333.0|782.0|1099.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-02802,C3L-02802,No,b1,3,130N,CPT0174890008,Tumor,No,56,Female,Endometrioid carcinoma,G1 Well differentiated,5.6,170,118,40.75,Present,<50% myometrial invasion,Eighth Edition (2017),pT2 (FIGO II),pN0,5,Stage II,White,NA,NA,No,0.01,MSS,NA,62,WT,Mutated,WT,WT,WT,7.50E-02,3.73E-02,0,0,1.84E-18,7.48E-19,0,3.96E-19,0,1.54E-04,1.16E-18,3.11E-02,2.01E-03,0,6.91E-03,4.59E-03,0,3.39E-02,0,7.58E-02,5.46E-03,7.47E-03,1.24E-02,6.88E-03,0,5.58E-18,1.16E-02,9.66E-19,8.41E-19,3.07E-18,2.87E-02,4.08E-03,0,1.94E-02,5.12E-02,2.00E-02,3.77E-02,1.95E-02,5.72E-02,0,0,0.101281922,3.00E-02,0,0.279683089,0,2.80E-02,0,0,3.21E-02,3.27E-02,1.36E-02,0,1.16E-02,0.350116517,4.78E-02,0,7.33E-02,0,0,0,17,37,0,0,0,0,0,0,0,0,0,NA,Yes,Yes,0.775085641,-1.558194899,-0.390610225,-1.030024653,-0.513403734,-1.015309655,-0.415125526,0.732860877,-0.243031102,-0.346188022,-0.464713404,0.311253083,-0.350183655,-0.646846385,4250.972659,4203.374447,8454.347106,Atypical and/or suspicious,Not identified,Cannot be assessed,Not-Hispanic or Latino,Caucasian,Other: TSS did not collect this information.,Other,Anterior and posterior endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,3,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,1,NA,NA,Unknown,"Consumed alcohol in the past, but currently a non-drinker",Current reformed smoker within past 15 years,Unknown,Unknown,Unknown,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Lisinopril|Metformin|Paroxetine,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|Yes,Living|Living|Living,404|690|844,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown Tumor Status|Unknown Tumor Status|Unknown Tumor Status,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Yes|Yes|Yes,Yes|Yes|Yes,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|n/a,n/a|n/a|Unknown,Unknown|Unknown|Unknown,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,404.0|690.0|844.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-02894,C3L-02894,No,b2,8,129C,CPT0196790004,Tumor,No,67,Female,Serous carcinoma,G3 Poorly differentiated,9,170,124,42.75,Present,<50% myometrial invasion,Eighth Edition (2017),pT3b,pN1,1,IVB,White,32.26682434,CNV_H,No,0.47,MSS,CNV_H,31,Mutated,WT,WT,WT,Mutated,0.116052251,3.07E-03,0,0,0,4.91E-18,6.54E-19,0,3.55E-03,2.64E-02,9.10E-20,2.03E-03,1.44E-02,0,9.05E-03,4.18E-03,6.22E-03,3.08E-18,4.12E-18,4.47E-02,1.96E-02,1.19E-02,6.14E-03,1.44E-02,7.20E-19,2.91E-04,1.05E-03,0,8.45E-18,6.31E-02,1.75E-02,1.37E-02,4.12E-03,2.67E-02,7.72E-02,3.53E-02,3.75E-02,2.09E-03,3.96E-02,1.87E-02,0,3.92E-02,4.22E-03,0,0.389947278,1.24E-02,3.43E-02,0,0,1.82E-02,3.76E-02,0,0,0.125831425,0.308898825,8.39E-03,2.21E-03,0,0,0,0,0,10,13,0,0,6,0,0,0,0,0,0.5,NA,NA,-0.302656356,-1.89215291,1.717822789,5.69E-02,1.634944881,-2.429994437,-0.345932677,-0.717609346,1.553613754,-0.920875207,-0.557953488,-0.147590392,0.335801798,-1.614018749,3864.565935,4180.945317,8045.511252,Positive for malignancy,Not identified,Margin(s) involved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Anterior endometrium,NA,Unifocal,IHC staining not done,1,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,R2: Macroscopic residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Overexpression,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,None,Ki-67 is increased,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Allopurinol|Neurontin|lisinopril |toprol XL|multivitamin,NA,NA,NA,NA,Yes,1,12 Months,No,Deceased,428,Yes,Yes,No,With Tumor,Unknown,Unknown,Unknown,No,No,None,No,Persistent Disease,Patient Deceased,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,Other : Serous carcinoma of uterine,431,n/a,n/a,n/a +C3L-02953,C3L-02953,No,b4,14,129N,CPT0161590008,Tumor,No,56,Female,Endometrioid carcinoma,G1 Well differentiated,3.5,160,83,32.42,Not identified,NA,Seventh Edition (2010),pT1a (FIGO IA),pN0,0,Stage I,White,3.002217572,CNV_L,No,0.04,MSS,CNV_L,50,WT,Mutated,WT,Mutated,WT,2.31E-02,7.82E-03,6.78E-03,6.67E-19,7.14E-18,1.22E-17,2.04E-18,3.33E-03,1.26E-19,8.50E-03,5.55E-18,9.18E-03,3.82E-02,4.19E-19,2.20E-03,9.63E-19,1.58E-19,5.59E-03,0,5.43E-02,2.76E-04,0,6.97E-03,3.88E-03,2.69E-18,0,6.96E-03,0,0,0,7.73E-03,1.12E-02,0,7.74E-02,0.141421964,0,9.45E-03,2.80E-03,1.22E-02,1.99E-02,0,0,0,0,0.403147937,0,0,0,4.34E-02,0,8.87E-02,0,0,4.23E-02,0.197120605,0.101290754,1.55E-02,6.24E-02,0,2.62E-02,0,18,30,0,0,0,0,0,0,0,0,0,0.25,NA,NA,-0.809465177,-1.892438555,0.368169932,-1.520651544,-0.325254897,-2.145732302,-0.732143709,-0.576884602,-0.264900823,-1.028471118,-0.744663868,-0.435615665,0.207689789,-0.978108343,2859.960218,3016.273958,5876.234176,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Hispanic or Latino,Hispanic,United States,Other,Anterior and Posterior,Unifocal,IHC staining not done,0,0,IHC staining not done,0,5,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,4 or more,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Flonase|lisinopril |imitrex,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,464|652|1063,No|No|No,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Never|Never|Never,Yes|Yes|Yes,No|No|No,4 or more|4 or more|4 or more,No|No|No,Not Applicable|Not Applicable|Not Applicable,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,464.0|652.0|1063.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-02990,C3L-02990,No,b2,6,131N,CPT0238260003,Tumor,No,67,Female,Serous carcinoma,G3 Poorly differentiated,5.3,155,53,22.2,Present,=50% myometrial invasion,Eighth Edition (2017),pT1b,pN1,3,IB,White,15.39006414,CNV_H,No,1.17,MSS,CNV_H,72,Mutated,WT,WT,WT,WT,7.91E-02,2.84E-02,3.56E-03,2.10E-18,1.63E-19,7.55E-19,5.20E-18,1.10E-02,2.39E-19,3.62E-03,2.84E-18,8.89E-19,1.94E-02,6.46E-19,0,1.90E-03,2.14E-19,1.28E-02,1.59E-17,1.64E-02,1.64E-02,2.42E-02,2.07E-03,1.02E-03,2.11E-03,0,5.55E-03,5.78E-19,0,1.12E-02,3.43E-02,6.71E-03,1.18E-02,7.66E-02,0.179428212,0,3.05E-02,9.26E-03,3.98E-02,2.33E-03,0,2.33E-04,5.97E-02,0,0.249125649,1.67E-02,2.25E-02,0,2.69E-02,0,6.90E-02,0,0,0.108754988,0.29473712,0,8.08E-02,0,4.80E-02,0,2.11E-02,23,47,0,0,0,0,0,0,0,0,0,0.79,NA,NA,-1.136808914,-0.18967163,-2.065544496,-1.377735401,0.626819451,0.784653339,-0.705770149,-1.190684684,0.328633076,-0.327609874,-0.981983691,-1.717230186,-0.673944479,-0.457005729,3038.314743,3320.857845,6359.172588,Not Examined,Not identified,Cannot be assessed,Not-Hispanic or Latino,Caucasian,United States,Other,Endomyometrium - posterior and anterior,Multifocal,1,1,0,0,0,0,0,0,IB,R0: No residual tumor,Positive : % Not available,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,None,"CD10=possible stroma, Ki-67 proliferative, Her2neu negative, P16 positive, Wilms Tumor positive, Beta-Catenin Positive, PTEN positive",NA,No,Alcohol consumption history not available,"Current reformed smoker, more than 15 years",23,63,Unknown,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Medical Record|Medical Record|Medical Record,Naproxen|Valtrex|Evista|Melatonin|Magnesium Oxide|Calcium Citrate D3,NA,NA,NA,NA,Yes,1,12 Months,Yes,Living,274,Yes,Yes,No,Unknown Tumor Status,Former Therapy,Unknown,Never,No,No,None,No,Not Applicable,Not Applicable,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,251,n/a,n/a,n/a,n/a,n/a +C3L-03143,C3L-03143,No,b4,15,127N,CPT0234080003,Tumor,No,67,Female,Serous carcinoma,Other: Not specified.,6,165,76,27.79,Present,<50% myometrial invasion,Eighth Edition (2017),pT3b,Not assessed,Unknown value,IVB,Asian,48.06698584,CNV_H,No,0.74,MSS,CNV_H,80,Mutated,WT,WT,WT,WT,0.164961528,4.83E-02,6.25E-03,1.15E-18,0,7.38E-18,0,3.71E-03,0,6.37E-03,0,1.19E-02,3.88E-02,0,4.46E-03,2.56E-03,4.75E-19,3.44E-18,2.30E-18,2.07E-02,8.89E-02,6.63E-02,6.30E-02,1.19E-02,0,5.68E-03,4.51E-03,0,3.32E-18,1.21E-02,3.07E-02,2.06E-02,1.97E-02,0.156393402,0.121081541,0,0.106185887,1.28E-03,0.107466999,5.61E-03,0,5.93E-02,1.44E-02,0,0.156323105,0,2.81E-02,8.87E-03,0,0,6.09E-02,4.56E-03,0.1251209,3.23E-02,0.484311913,0,1.50E-03,1.13E-02,0,0,7.51E-03,18,58,0,0,0,0,0,0,0,0,0,0.24,Yes,No,-1.795173579,-0.242445775,-1.823740404,-0.325799406,0.280835724,-0.917153033,-0.338774305,-2.406594955,0.661974435,-1.186250662,-0.492380375,-0.5718681,1.742996723,-1.638259025,3480.166403,5296.123459,8776.289862,Not Examined,Not identified,Margin(s) involved by invasive carcinoma,Not-Hispanic or Latino,Indian,Other: India,Anterior endometrium,NA,Multifocal,IHC staining not done,0,Unknown value,IHC staining not done,0,Unknown value,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Unknown,Cannot be determined,Unknown,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,NA,NA,Yes,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record,No,NA,NA,Breast,Medical Record,"Radiation,Surgery",Yes,Yes,2,12 Months|24 Months,No|No,Living|Living,389|767,Yes|Yes,Yes|Yes,No|No,With Tumor|With Tumor,Unknown|Unknown,Unknown|Unknown,Former Therapy|Former Therapy,Yes|Yes,Yes|Yes,2|2,No|No,Unknown|Unknown,Persistent Disease|Persistent Disease,n/a|n/a,No|Yes,n/a|Distant Metastasis,n/a|Other: retroperitoneal lymph nodes and left axilary lymph node,n/a|585.0,n/a|No,n/a|Yes,n/a|No,n/a|No,389.0|767.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-03264,C3L-03264,No,b4,13,131C,CPT0225010003,Tumor,No,73,Female,Endometrioid carcinoma,G2 Moderately differentiated,2.5,160,91,35.43,Present,=50% myometrial invasion,Eighth Edition (2017),pT1b (FIGO IB),pN0,17,Stage IB,White,3.684774312,CNV_L,No,13.39,MSI-H,MSI-H,773,Mutated,Mutated,WT,Mutated,Mutated,0.26994991,8.37E-02,1.74E-02,7.77E-18,0,0,3.05E-02,2.20E-03,3.46E-02,7.49E-02,2.19E-02,1.68E-03,2.71E-02,0,7.36E-03,0,0,5.08E-19,0,1.02E-19,0.14831925,9.96E-02,7.29E-02,5.61E-03,3.21E-05,5.49E-03,7.90E-03,7.70E-03,4.61E-18,9.22E-03,0.121754587,2.86E-02,3.94E-02,0.134016256,0.272077579,0,0.195172954,4.93E-19,0.195172954,0,1.76E-03,4.31E-02,0.182054303,0,1.80E-02,7.74E-02,5.12E-02,1.48E-02,0,0,8.77E-02,0,5.52E-02,0.141830531,0.197392313,0,0,4.59E-02,0,0,8.37E-02,69,16,0,0,0,0,143,124,0,169,64,0.54,NA,NA,-2.200524627,1.135158314,-1.546455211,0.494836154,2.795392137,1.031519067,2.063841158,-2.164076062,2.171478151,-1.515637629,1.695372992,0.372870976,1.037453216,-1.942804878,3734.259429,7173.677855,10907.93728,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,Caucasian,United States,Posterior endometrium,NA,Unifocal,IHC staining not done,0,12,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,NA,NA,Yes,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Atenolol|Diltiazem HCL|Hydrochlorothiazide|Meloxicam|Metformin|Toviaz|Voltaren (topical)|Vytorin|Xarelto|Xiidra|Docusate Sodium|Polyethylene Glycol|Potassium Chloride|Senna,Melanoma,Medical Record,Unknown,Unknown,Yes,2,12 Months|24 Months,No|No,Living|Living,507|847,Yes|Yes,No|No,No|No,Unknown Tumor Status|Unknown Tumor Status,Unknown|Unknown,Unknown|Unknown,Unknown|Unknown,Yes|Yes,No|No,2|2,No|No,Unknown|Unknown,Unknown|Unknown,n/a|n/a,Unknown|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,507.0|847.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-03467,C3L-03467,No,b1,4,128C,CPT0188610003,Tumor,No,73,Female,Serous carcinoma,G3 Poorly differentiated,3.2,160,83,32.59,Present,=50% myometrial invasion,Eighth Edition (2017),pT2 [II],pN1 [IIIC1,5,Stage IIIC1: T1-3/N1/M0,White,44.08377525,CNV_H,No,0.22,MSS,CNV_H,57,Mutated,WT,WT,WT,WT,3.32E-02,4.02E-02,1.28E-20,1.54E-18,5.93E-18,6.21E-18,6.35E-19,1.15E-18,1.45E-19,0,1.29E-17,0,1.36E-02,2.28E-03,4.62E-20,0,0,0,1.90E-02,1.65E-02,1.23E-03,2.17E-03,9.99E-03,1.79E-02,6.40E-03,2.14E-18,1.50E-02,2.53E-21,8.70E-18,1.80E-19,0,6.56E-03,0,1.28E-02,9.18E-02,6.49E-18,3.96E-02,1.77E-03,4.13E-02,0.128349982,0,1.40E-02,0.106646197,0,0.124215886,0,7.69E-02,0,0,0,2.63E-02,7.18E-03,5.29E-02,2.24E-02,0.20326056,1.23E-03,1.95E-02,7.26E-02,0.113727205,2.60E-02,4.89E-03,21,32,0,0,0,0,0,0,0,0,0,0.24,NA,NA,-0.73986979,-6.77E-02,-3.18E-02,-0.945841428,1.09690119,0.712829537,0.680169252,-0.979397066,-1.112269404,0.336409659,0.638153991,-0.159035122,-0.935291549,0.285347859,3473.636966,3185.651842,6659.288808,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Endometrium,Unifocal,1,1,7,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Former Therapy,2,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Famotidine|Levothyroxine Sodium|Lexapro|Vitamin B12|Vitamin D,NA,NA,NA,NA,Yes,2,12 Months,Yes,Living,410,No,Yes,No,Tumor Free,Former Therapy,Former Therapy,Never,No,No,2,No,Complete Remission,Complete Remission,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,383,n/a,n/a,n/a,n/a,n/a +C3L-03589,C3L-03589,No,b3,9,130C,CPT0188710003,Tumor,No,59,Female,Endometrioid carcinoma,G2 Moderately differentiated,0.7,173,130,43.48,Not identified,NA,Eighth Edition (2017),pT1a [IA],pN0,4,Stage IA,White,0,CNV_L,No,24.9,MSI-H,MSI-H,762,WT,Mutated,WT,Mutated,WT,5.45E-02,1.10E-02,0,0,0,1.29E-17,8.15E-19,0,1.23E-18,2.02E-18,8.40E-18,3.63E-20,3.09E-02,8.92E-18,3.51E-03,5.66E-21,2.46E-18,0,2.58E-18,9.83E-03,8.67E-03,6.39E-03,3.75E-03,1.81E-03,0,5.81E-19,5.59E-03,7.06E-19,4.29E-17,1.54E-02,3.29E-02,1.51E-02,3.91E-18,5.61E-02,0.146281241,0,1.66E-02,1.26E-20,1.66E-02,4.93E-02,0,5.94E-02,4.50E-02,0,0.146977081,2.45E-02,4.97E-02,0,0,0,3.40E-02,0,0.125292068,6.68E-02,0.138192484,5.25E-03,0,0,0.166581636,1.71E-02,7.19E-02,0,115,238,0,0,0,0,127,0,0,103,0.5,NA,NA,-0.356254436,0.949837004,0.732015304,0.344629367,-0.336280134,1.364646756,1.918183314,-0.307795601,0.35610709,-0.921718338,1.796789357,-1.247110478,2.065531641,5.10E-02,2482.930503,4395.756138,6878.686641,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,White,United States,Other,Endometrium,Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,No,Present,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,None,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Current reformed smoker within past 15 years,14,58,Unknown,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Esomeprazole Magnesium|Levothyroxine |Simvastatin,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|Yes,Living|Living,427|883,No|No,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Unknown|Unknown,Yes|Yes,No|No,None|None,No|No,Complete Remission|Complete Remission,Unknown|Unknown,n/a|n/a,Unknown|Unknown,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,417.0|873.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-05571,C3L-05571,No,b4,16,131N,CPT0275270003.1,Tumor,No,58,Female,Serous carcinoma,G3 Poorly differentiated,8.2,165,86,31.48,Present,=50% myometrial invasion,Eighth Edition (2017),1b,1a,14,-1,Black or African American,17.9472104,CNV_H,No,0.09,MSS,CNV_H,42,Mutated,WT,WT,WT,Mutated,0.114268749,5.35E-03,1.15E-20,0,3.46E-18,9.53E-19,0,4.21E-03,0,4.60E-19,0,3.97E-18,7.08E-03,0,1.94E-03,2.80E-20,3.98E-19,5.25E-18,0,5.70E-02,1.51E-02,1.88E-02,8.26E-03,3.66E-03,0,0,2.35E-03,2.32E-19,5.04E-18,7.90E-03,3.39E-02,1.23E-03,0,5.10E-02,0.148970878,0,1.73E-02,2.70E-18,1.73E-02,5.48E-02,0,7.14E-03,7.03E-03,0,0.222205039,0,3.44E-02,2.00E-02,0,5.87E-02,0,2.49E-02,7.91E-02,4.01E-02,0.274873476,0,8.01E-02,0,1.94E-02,6.02E-02,1.69E-02,18,20,0,0,0,0,0,0,0,0,0,0.21,NA,NA,-1.384619954,-0.314596071,-1.131237614,0.41941826,2.268785111,0.304576868,-0.13962301,-1.0273441,1.154439286,-0.551835445,-0.184775839,-0.463593241,0.806508233,0.519192186,2886.147055,3651.024917,6537.171972,Negative for malignancy/normal/benign,Not identified,Cannot be assessed,Not-Hispanic or Latino,Black,United States,Posterior endometrium,NA,Multifocal,0,0,4,0,0,0,0,0,Staging Incomplete,R0: No residual tumor,Positive : 65 %,Positive : 2 %,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Overexpression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record,Yes,Medical Record|Medical Record|Medical Record,Celebrex|guaifenesin|naproxen,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|Yes,Living|Living,298|449,Yes|Yes,Yes|Yes,Yes|No,Tumor Free|With Tumor,Never|Never,Former Therapy|Former Therapy,Never|Never,No|No,No|No,2|1,No|Unknown,Complete Remission|Persistent Disease,Complete Remission|n/a,n/a|Persistent Disease,No|Unknown,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,298.0|449.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3L-05571-b1,C3L-05571,Yes,b1,4,131C,CPT0275270003,Tumor,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-05848,C3L-05848,No,b1,1,129C,CPT0288750003,Tumor,No,70,Female,Serous carcinoma,G3 Poorly differentiated,-2,165,53,19.3,Present,<50% myometrial invasion,Eighth Edition (2017),pT3a,pN0,2,IVB,White,23.02237376,CNV_H,No,0.13,MSS,CNV_H,190,Mutated,WT,WT,WT,Mutated,0.133982091,1.83E-02,6.14E-03,0,3.43E-18,3.22E-19,1.03E-02,3.83E-03,0,2.47E-19,0,1.46E-19,3.06E-02,5.40E-20,1.11E-02,3.50E-03,2.23E-19,0,8.39E-03,2.12E-02,4.08E-02,3.28E-02,1.15E-02,2.96E-03,9.85E-21,1.20E-02,6.68E-03,5.90E-03,0,0,2.13E-02,1.08E-03,0,0,0.23338744,1.62E-18,6.07E-02,1.75E-03,6.24E-02,0,0,4.49E-02,3.29E-02,0,0.209211775,0,4.59E-02,0,0,0,7.64E-02,0,3.31E-02,3.01E-02,0.247757337,4.39E-02,3.65E-02,0,9.03E-02,2.64E-02,8.27E-02,4,119,0,62,0,0,0,0,0,0,0,0.23,NA,NA,2.62E-02,1.056713158,-5.22E-02,-1.322776134,0.177598276,0.662110775,1.510200793,-0.162670933,0.9932458,0.442598882,1.480251765,0.922565198,-1.654268392,1.045739467,4756.659794,5475.906105,10232.5659,Not Examined,Not identified,Cannot be assessed,Not-Hispanic or Latino,White,Other: Unknown,Other,Endometrium,Unifocal,0,0,0,0,0,0,0,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,No,Absent,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,calcium carbonate/vitamin D3 |Naproxen|Propranolol |ibuprofen,NA,NA,NA,NA,Yes,2,12 Months,No,Deceased,153,No,Yes,No,With Tumor,Never,Unknown,Never,No,No,2,No,Persistent Disease,Persistent Disease,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,Other : Endometrial Carcinoma,153,n/a,n/a,n/a +C3L-05849,C3L-05849,No,b3,10,131N,CPT0288830003,Tumor,No,64,Female,Serous carcinoma,G3 Poorly differentiated,95,165,80,29.35,Present,=50% myometrial invasion,Eighth Edition (2017),pT2,PN2a,6,IIIC2,Black or African American,15.89601897,CNV_H,No,0.01,MSS,CNV_H,59,WT,WT,WT,WT,WT,0.401764688,0.124726736,4.84E-02,1.37E-02,1.39E-02,2.96E-18,0.138651888,0,2.17E-02,6.00E-02,0,3.38E-02,2.59E-02,0,2.70E-02,5.99E-02,1.27E-19,5.25E-02,6.08E-20,6.29E-02,0.129562923,0.108230892,3.49E-02,3.94E-03,2.63E-02,0.121764701,1.93E-02,0,1.48E-19,2.94E-02,8.28E-02,8.09E-03,2.83E-03,0,0.152181899,4.43E-02,0.295071247,6.13E-02,0.356335552,2.21E-02,0,1.49E-02,4.36E-02,5.21E-03,0.257167925,3.77E-02,0,0,0,3.91E-02,0,1.16E-02,0.138619362,7.64E-02,0.273111105,0,2.31E-02,0,4.13E-02,4.02E-03,1.21E-02,21,35,0,0,0,0,0,0,0,0,0,0.18,Yes,No,2.57E-02,1.008324896,0.471269094,-0.759199592,2.307381318,0.73200949,2.19771132,0.604381722,0.10293743,0.185554515,1.98110734,2.310609056,-0.581266888,-0.113105162,6400.839955,8045.434992,14446.27495,Negative for malignancy/normal/benign,Present,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,Black,United States,Other,Endometrium,Unifocal,IHC staining not done,2,16,IHC staining not done,12,Unknown value,IHC staining not done,0,Staging Incomplete,R0: No residual tumor,Positive : 80 %,Positive : 80 %,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of expression,Yes,Absent,Yes,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,p16 - Diffusely reactive,Ki-67 highlights 70-80% of tumor,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,amLODIPine|Cabergoline|Calcium carb-mag oxide-vit D3 |Citalopram|Potassium|RaNITIdine |TraZODone,NA,NA,NA,NA,Yes,2,12 Months,No,Living,385,No,Yes,No,Tumor Free,Never,Never,Never,Yes,Yes,1,No,Complete Remission,Complete Remission,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,373,n/a,n/a,n/a,n/a,n/a +C3N-00155,C3N-00155,No,b4,15,129N,CPT0104820003,Tumor,No,57,Female,Endometrioid carcinoma,G1 Well differentiated,0,165,126,46.28,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,0,Stage I,NA,0,CNV_L,No,0.84,MSS,CNV_L,175,WT,Mutated,WT,Mutated,Mutated,9.04E-02,1.04E-02,4.28E-19,1.99E-18,6.03E-18,0,0,0,0,0,0,7.75E-04,0,4.17E-18,6.60E-03,4.04E-03,5.37E-19,0,0,3.62E-02,2.42E-02,2.56E-02,8.79E-03,2.96E-03,3.61E-19,0,5.73E-03,1.39E-02,5.82E-18,2.85E-02,2.48E-02,5.47E-03,0,0.116365435,2.04E-03,0,3.87E-02,4.71E-03,4.34E-02,0,0,3.89E-02,8.17E-03,0,0.219529533,0,1.56E-02,1.87E-02,0,0,0.128373163,0,8.14E-02,1.38E-02,0.201141274,4.56E-02,3.43E-03,0,3.45E-02,0,0.190958924,10,52,72,0,0,0,0,0,0,0,0,0.17,NA,NA,-0.374553388,-0.289790261,1.121605755,-0.312409698,0.263218036,-1.451544947,0.786626642,0.235738782,0.431825143,-0.186178109,0.811559247,0.696742021,0.134654558,-2.37E-02,4354.35758,4945.367245,9299.724825,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Ukraine,Posterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,Unknown,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,1,12 Months,Yes,Living,18,Unknown,Unknown,Unknown,Unknown Tumor Status,Unknown,Unknown,Unknown,Unknown,Unknown,Unknown,Unknown,Unknown,Unknown,n/a,Unknown,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a +C3N-00520,C3N-00520,No,b2,7,131C,CPT0115000004,Tumor,No,58,Female,Endometrioid carcinoma,G1 Well differentiated,4,154,75,31,Present,=50% myometrial invasion,Seventh Edition (2010),pT3a (FIGO IIIA),pN0,8,Stage III,NA,0.388013171,CNV_L,No,0.01,MSS,CNV_L,39,WT,Mutated,Mutated,WT,WT,2.74E-02,0,7.46E-20,5.96E-20,3.38E-18,5.07E-19,2.35E-02,0,7.96E-19,0,3.36E-19,4.76E-03,0,0,2.36E-03,0,2.12E-18,7.51E-02,0,8.67E-02,9.14E-04,4.32E-03,2.33E-03,5.25E-03,1.45E-18,0,1.75E-19,3.38E-19,1.30E-19,9.22E-03,4.16E-03,1.85E-02,5.13E-18,7.26E-03,3.33E-18,0,5.68E-03,3.82E-02,4.39E-02,5.10E-02,0,0.118470449,3.79E-02,0,0.248511895,0,8.87E-02,0,0,0,3.56E-02,1.12E-02,4.18E-03,0,0.294056151,6.02E-02,0,5.02E-02,0,0,0,11,24,0,0,0,0,0,0,0,0,0,0.5,NA,NA,3.415209041,-0.56644536,0.164344889,-0.382919656,-1.122017538,-0.353273327,-1.091400146,0.61448874,-0.53563564,0.859388667,-0.860110525,-0.754691908,-0.876800191,0.616814696,4178.702317,3528.21591,7706.918227,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,1,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,NA,Yes,Medical Record|Medical Record|Medical Record,citrafleet|fragmin|kalipoz,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Deceased,120|638|974|1169,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|With Tumor,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,No|No|No|No,No|No|No|No,1|1|1|1,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|Persistent Disease,n/a|n/a|n/a|n/a,No|No|No|Yes,n/a|n/a|n/a|Distant Metastasis,n/a|n/a|n/a|Liver,n/a|n/a|n/a|1124.0,n/a|n/a|n/a|No,n/a|n/a|n/a|No,n/a|n/a|n/a|Yes,n/a|n/a|n/a|No,132.0|650.0|986.0|n/a,n/a|n/a|n/a|Malignant Neoplasm,n/a|n/a|n/a|1239.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-00732,C3N-00732,No,b2,7,127C,CPT0089600003,Tumor,No,56,Female,Endometrioid carcinoma,G1 Well differentiated,2.2,168,107,38.09,Not identified,NA,Seventh Edition (2010),pT1a (FIGO IA),pN0,16,Stage I,White,4.70E-03,CNV_L,No,0.05,MSS,CNV_L,55,WT,WT,Mutated,WT,Mutated,3.37E-02,2.83E-19,3.45E-04,5.27E-18,1.06E-18,1.54E-21,1.94E-02,1.15E-02,2.99E-02,4.19E-02,3.38E-18,2.59E-18,8.99E-03,1.63E-03,3.42E-03,1.73E-02,0,0.102854363,0,9.45E-02,2.99E-03,6.79E-03,1.68E-03,6.43E-03,7.62E-19,2.39E-03,0,1.54E-04,0,2.57E-03,6.77E-03,6.35E-03,0,2.29E-02,1.26E-02,1.68E-02,3.02E-02,6.01E-02,9.03E-02,5.81E-02,0,2.14E-02,4.12E-02,0,0.335995816,1.30E-02,0,0,2.17E-02,0,3.03E-02,3.33E-02,5.94E-02,6.76E-04,0.183489103,0,5.60E-03,0.172183947,0,2.35E-02,0,14,36,0,0,0,0,0,0,0,0,0,0.74,Yes,No,1.281583094,0.344033172,0.792653576,-0.851252327,-2.04783258,1.267562224,-0.537584745,1.140270672,-0.18848291,0.968124511,-0.408493069,-0.90066271,-0.992093506,2.390558613,4748.579197,3968.887673,8717.46687,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,white,United States,Anterior endometrium,NA,Multifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Perimenopausal: 6-12 months since last menstrual Period,Never,None,see below comment,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,albuterol|Duloxetine |insulin aspart|insulin glargine|meloxicam|pantoprazole|Ranitidine|simvastatin,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,411|795|1126|1393,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Unknown|Unknown|Unknown|Unknown,Never|Never|Never|Never,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,None|None|None|None,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,365.0|749.0|1080.0|1347.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-00750,C3N-00750,No,b4,16,127C,CPT0265110003,Tumor,No,44,Female,Endometrioid carcinoma,G2 Moderately differentiated,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,White,4.069838891,CNV_L,No,0.03,MSS,CNV_L,122,WT,Mutated,Mutated,WT,WT,5.91E-04,0,1.96E-20,0,7.54E-18,0,0,0,0,0,1.79E-19,0,3.18E-03,7.77E-18,0,1.67E-18,1.57E-19,7.76E-03,8.65E-18,0,0,0,0,1.68E-03,5.45E-18,0,0,0,5.32E-18,7.51E-03,1.31E-02,1.97E-03,0,8.75E-02,6.41E-02,0,1.12E-03,6.00E-03,7.12E-03,0,0,3.45E-03,6.14E-03,0,0.282786595,0,0,7.64E-03,0,9.49E-02,0,0,0.313552183,0,0.21834091,0,7.32E-02,0,0,0,0,37,57,0,17,0,0,0,0,0,0,0,0.4,NA,NA,-0.560139313,0.799378482,0.345423557,2.295443066,-0.706807355,0.772592175,-0.346099661,1.473413909,1.838931664,5.65E-02,-1.10E-02,-1.185084524,1.204169953,0.738238381,2901.657976,2816.021258,5717.679233,NA,NA,NA,Hispanic or Latino,Hispanic or Latino,Other: Unknown,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-00753,C3N-00753,No,b4,14,127C,CPT0129640003,Tumor,No,51,Female,Endometrioid carcinoma,G3 Poorly differentiated,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Asian,5.439517525,CNV_L,No,23.27,MSI-H,MSI-H,1855,WT,Mutated,WT,Mutated,Mutated,0.248709586,6.63E-02,7.99E-03,2.86E-03,2.08E-20,1.11E-18,7.44E-03,8.90E-03,2.77E-02,2.68E-02,1.48E-02,3.33E-02,2.31E-02,0,2.19E-02,9.14E-03,1.14E-18,1.06E-02,5.35E-19,1.21E-02,3.64E-02,3.96E-02,1.17E-02,9.26E-04,1.28E-18,2.60E-03,0,0,0,2.29E-02,7.79E-02,1.32E-02,9.71E-18,0.113754093,0.207907802,0,0.103872701,1.14E-02,0.115266428,3.03E-02,0,5.79E-02,0.109810609,0,0.152099328,6.13E-02,8.53E-02,0,0,1.98E-02,1.43E-02,0,8.99E-02,8.95E-02,0.230033669,0,1.65E-02,0,2.99E-02,0,1.34E-02,0,42,710,0,0,0,0,0,262,0,381,0.28,NA,NA,-1.166468405,1.359253342,-0.549850734,-0.117554452,1.899269333,1.326601228,0.773041072,0.10522105,0.147770966,9.95E-02,0.705746679,-0.136648547,0.47250482,8.26E-02,4933.254317,6033.839712,10967.09403,NA,NA,NA,Not-Hispanic or Latino,Non-Hispanic,Other: unknown,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-00755,C3N-00755,No,b2,7,130C,CPT0129520003,Tumor,No,42,Female,Endometrioid carcinoma,G1 Well differentiated,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Not Reported,0,CNV_L,No,0,MSS,CNV_L,31,WT,Mutated,WT,Mutated,Mutated,1.88E-02,4.03E-03,0,8.55E-19,6.90E-18,3.67E-02,7.13E-02,1.49E-18,0,1.91E-20,0,3.25E-02,2.95E-18,0,1.00E-02,0,3.19E-02,7.43E-02,0,1.23E-02,4.09E-19,7.68E-04,1.50E-03,6.88E-03,8.69E-18,0,0,0,6.51E-19,6.78E-02,1.77E-02,6.61E-03,0,2.35E-02,0,0,3.52E-02,3.87E-02,7.39E-02,3.37E-02,0,7.68E-02,0.102958021,0,0.364702102,0,1.27E-02,7.07E-03,0,5.21E-02,0,5.63E-03,5.47E-02,9.28E-03,5.54E-02,3.49E-02,2.23E-02,0.114542263,0,0,5.32E-02,5,10,0,0,2,5,5,0,0,0,0,0.21,NA,NA,0.317408249,0.909689511,1.35503569,-0.596165032,-0.472720313,-1.34E-02,0.274011505,0.650156366,-1.078573686,1.91E-02,0.5196641,0.597370721,-0.380419227,0.797239601,3799.267126,4355.661811,8154.928937,NA,NA,NA,Hispanic or Latino,Hispanic or Latino,Other: unknown,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-00859,C3N-00859,No,b4,16,130N,CPT0116010004,Tumor,No,60,Female,Other,G2 Moderately differentiated,9,170,121,41,Present,=50% myometrial invasion,Eighth Edition (2017),pT3b,pN0,5,Stage IIIB,NA,2.03E-03,CNV_L,No,0.01,MSS,CNV_L,85,WT,WT,Mutated,WT,WT,5.07E-02,0,3.43E-20,1.68E-18,1.43E-18,0,0,0,3.57E-18,0,0,0,0,0,0,3.77E-03,0,0.147814991,0,3.37E-02,1.85E-03,1.50E-02,0,5.89E-03,0,0,0,0,5.68E-18,6.13E-19,1.92E-02,8.06E-03,0,5.64E-02,9.50E-02,0,5.16E-03,7.99E-02,8.50E-02,0,0,6.99E-02,4.36E-02,0,0.166125082,0,8.13E-02,0,2.13E-02,0,7.75E-02,4.08E-02,0,1.80E-02,0.346618089,0,5.73E-02,7.76E-02,0,0,0,30,52,0,0,0,0,0,0,0,0,0,0.35,NA,NA,-0.355841341,0.949596302,0.509884697,0.344707027,7.43E-02,0.829933884,-0.501319963,1.379621481,0.790181976,0.634357178,-0.2743769,-0.293629283,0.264688355,-0.430693492,4213.747375,3389.428758,7603.176133,Negative for malignancy/normal/benign,Not identified,Cannot be assessed,NA,Caucasian,Poland,Fundus,NA,Multifocal,0,0,0,0,0,0,0,0,0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,4 or more,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Offtensin|Tritace|Clexane|Exacyl|cyclonamine|Potassium Chloride|fortrans,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,377|722|1056|1440,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,No|No|No|No,4 or more|4 or more|4 or more|4 or more,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a|n/a,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,392.0|737.0|1071.0|1455.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-00860,C3N-00860,No,b4,15,128C,CPT0116140004,Tumor,No,67,Female,Endometrioid carcinoma,G1 Well differentiated,5.5,154,76,32,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pNX,0,Stage I,NA,2.16E-03,CNV_L,No,0.04,MSS,CNV_L,97,WT,Mutated,WT,WT,Mutated,3.96E-02,0,0,5.59E-19,1.38E-17,1.16E-02,5.34E-03,1.05E-18,9.96E-19,0,0,1.78E-02,2.00E-04,0,7.17E-03,1.42E-02,1.59E-19,3.14E-02,0,7.35E-02,0,3.64E-04,3.80E-03,7.39E-03,0,0,3.71E-19,0,1.50E-18,1.24E-02,1.76E-02,1.79E-03,3.86E-18,5.11E-02,2.07E-18,0,9.71E-03,2.28E-02,3.25E-02,0,2.04E-02,6.12E-02,4.07E-02,0,0.256280046,0,0,1.42E-02,0,0,5.78E-02,4.53E-04,4.17E-02,7.67E-03,0.396138995,1.81E-02,3.86E-03,7.01E-02,0,0,1.13E-02,15,39,0,0,0,12,20,0,0,0,0,0.45,NA,NA,0.663451845,-1.042030566,0.261304497,-1.286492731,-0.609085537,-1.379859068,-0.580944902,1.044305932,-0.291931793,-0.480919047,-0.294376313,0.96234935,-0.962555868,-0.250919023,3751.168781,3712.832239,7464.00102,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Unifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Absent,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Nebicard|Vanatex HCT|Fragmin|Potassium Chloride|fortrans,NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|Yes,Living|Living,351|451,Yes|Yes,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,No|No,2|2,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,364.0|464.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-00872,C3N-00872,No,b3,11,130N,CPT0116250004,Tumor,No,75,Female,Endometrioid carcinoma,NA,5.5,158,74,29.64,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,6,Stage I,NA,0,CNV_L,No,0.05,MSS,CNV_L,60,WT,Mutated,WT,Mutated,WT,7.26E-02,1.97E-02,0,0,8.19E-18,3.12E-18,4.45E-02,6.47E-04,7.72E-03,8.32E-03,0,7.96E-04,2.12E-03,0,3.18E-03,3.99E-19,0,2.10E-02,0,3.23E-02,1.24E-20,2.52E-04,4.25E-03,5.53E-03,0,1.02E-17,4.54E-03,0,9.92E-18,3.62E-02,1.02E-02,4.00E-02,6.16E-18,6.82E-02,5.63E-05,1.13E-02,2.41E-02,1.05E-02,3.46E-02,1.66E-02,0,0.157788327,0.127586723,0,0.205252977,0,4.06E-02,0,0,2.66E-02,0,6.66E-03,0.195866958,2.12E-02,0.136866067,0,0,0,6.51E-02,0,0,15,21,0,0,0,8,13,0,0,0,0,0.26,Yes,No,0.529870461,-0.269327231,0.954137734,1.055162237,-0.83937678,-0.765850621,-0.298832009,0.342006037,4.76E-02,-0.214148673,-0.213604886,0.277916899,0.107628576,-7.73E-02,3109.754015,3623.267678,6733.021693,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Other,Uterine cavity,Multifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,No,NA,NA,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,399|651|1106|1554,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,411.0|663.0|1118.0|1566.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-01007,C3N-01007,No,b1,2,130C,CPT0095100003,Tumor,No,59,Female,Endometrioid carcinoma,G2 Moderately differentiated,1.5,164,92,34,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,4,Stage I,NA,0,CNV_L,No,7.81,MSI-H,MSI-H,1075,Mutated,Mutated,Mutated,Mutated,Mutated,0.126893776,3.37E-02,7.71E-03,1.67E-18,0,0,2.01E-02,2.38E-03,1.60E-02,4.23E-02,0,4.58E-19,0,1.94E-19,3.46E-03,1.02E-18,0,0,0,9.63E-03,1.42E-02,9.47E-03,1.30E-02,4.31E-03,2.61E-03,2.89E-03,1.04E-02,2.52E-03,1.01E-17,2.27E-02,2.67E-02,1.31E-02,0,5.48E-02,0.129531956,1.54E-02,5.14E-02,5.10E-19,5.14E-02,1.92E-03,0,3.09E-02,5.85E-02,0,0.221617916,0,7.77E-02,0,7.21E-04,0,5.70E-02,0,0.1428905,0.123243905,0.125879396,3.05E-04,0,0,6.27E-02,9.09E-03,8.75E-02,409,154,454,0,0,0,0,0,0,0,0,0.7,NA,NA,-0.160785511,-0.928428143,-2.30E-02,0.660467572,1.092692701,-0.545833911,0.345920518,-0.731912121,9.64E-02,-1.218773649,0.316729301,-0.378349943,0.207863952,0.625548468,2972.189086,4667.48303,7639.672116,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Unifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : 70 %,Positive : 50 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Bisocard|Axtil|Aldac|Concor|Hydroxyzin|Fragmin,NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|Yes,Living|Living,364|364,No|No,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Unknown|Unknown,Never|Never,Yes|Yes,No|No,2|2,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|Unknown,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,376.0|376.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-01008,C3N-01008,No,b1,3,127C,CPT0095130004,Tumor,No,68,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.5,156,98,40,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,8,Stage I,NA,0,CNV_L,No,0.16,MSS,CNV_L,91,WT,Mutated,Mutated,WT,WT,4.80E-02,5.13E-03,0,2.66E-18,2.25E-18,1.07E-18,0,4.87E-04,1.57E-19,8.22E-03,7.01E-18,1.18E-02,1.35E-02,5.94E-03,2.78E-03,2.39E-19,1.39E-18,0,1.21E-18,1.64E-02,2.89E-03,5.78E-03,7.59E-04,5.50E-03,0,3.87E-18,3.16E-03,1.53E-19,3.71E-18,2.21E-02,1.63E-02,9.91E-04,0,2.86E-02,0.10970217,1.50E-03,1.09E-02,1.20E-19,1.09E-02,0,0,2.19E-02,5.18E-02,0,0.261957218,0,0,0,0,3.47E-02,5.64E-02,1.47E-02,4.50E-02,3.82E-03,0.276429343,6.89E-02,4.03E-02,0.124152219,0,0,0,30,56,0,0,0,0,0,0,0,0,0,0.84,NA,NA,0.189670667,0.266224453,-1.693862585,-0.210503442,-0.403409309,0.750945395,-0.912400656,0.454799384,2.131324119,-0.17124993,-0.611319975,-1.270733903,1.098963889,0.990166908,2920.666306,3286.44014,6207.106445,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Unifocal,0,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 90 %,Positive : 50 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,1,Ki67 positive 40%,NA,No,Lifelong non-drinker,Current smoker: Includes daily and non-daily smokers,20,NA,20,48,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record,Bespres|Polocard|Clexane,NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|Yes,Living|Living,347|318,Yes|Yes,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Unknown|Unknown,Never|Never,Yes|Yes,No|No,1|1,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,371.0|342.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-01079,C3N-01079,No,b1,2,131N,CPT0211120004,Tumor,No,77,Female,Endometrioid carcinoma,G1 Well differentiated,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,2.19E-02,CNV_L,No,0.27,MSS,CNV_L,56,Mutated,WT,WT,WT,WT,8.68E-02,0,0,6.04E-19,0,0,2.51E-02,4.41E-03,0,2.24E-02,9.63E-19,0,2.45E-02,0,5.64E-03,2.45E-02,5.71E-19,0.104588958,6.58E-18,0.100437458,7.48E-03,4.16E-03,9.49E-03,2.43E-03,0,0,0,5.97E-20,0,0,1.40E-02,1.40E-02,4.55E-18,1.73E-02,0.115950423,0,1.04E-02,6.90E-02,7.94E-02,4.81E-02,0,0.100444197,0,0,0.32654871,0,5.06E-03,0,5.34E-02,0,5.23E-02,4.26E-04,2.91E-02,3.41E-02,0.220740066,2.64E-02,2.91E-03,7.92E-02,0,0,2.13E-02,13,30,0,0,0,0,11,0,0,0,0,1,NA,NA,0.680457885,1.045625842,1.572270619,0.379230172,-0.920658346,1.537915387,-0.243829645,-0.98072042,-1.617707419,0.251512131,-0.295053867,-0.200529493,-0.185502919,0.728184302,4836.138544,3845.676546,8681.815089,NA,NA,NA,NA,Caucasian,Ukraine,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-01171,C3N-01171,No,b3,10,128C,CPT0095190003,Tumor,No,82,Female,Endometrioid carcinoma,G2 Moderately differentiated,4,164,88,32,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pNX,0,Stage I,NA,0,CNV_L,No,18.81,MSI-H,MSI-H,685,Mutated,Mutated,WT,Mutated,Mutated,0.111760853,1.93E-02,4.43E-03,3.30E-19,2.38E-21,1.33E-19,1.03E-02,8.39E-03,1.04E-02,1.73E-02,0,8.99E-03,1.92E-02,0,6.55E-03,8.34E-03,0,0,5.48E-18,1.13E-02,1.42E-02,1.45E-02,4.88E-03,1.30E-03,1.48E-18,1.03E-02,7.66E-03,1.86E-04,1.72E-18,7.80E-03,2.93E-02,3.39E-03,0,5.65E-02,0.145371868,0,4.16E-02,4.17E-03,4.58E-02,0,0,6.39E-02,0.150286416,0,0.130687333,0,8.47E-02,1.26E-02,0,0,7.15E-02,1.09E-02,0.120323693,8.21E-02,0.132281152,8.38E-03,0,0,9.64E-02,0,3.59E-02,48,12,134,0,0,0,126,92,0,0,60,0.59,Yes,No,-0.674945537,1.373998424,-3.64E-02,1.228499994,1.368713733,1.441871718,1.457994086,0.375543651,1.1153636,-0.1715209,1.317100488,0.189389964,-0.122353855,1.268667507,3989.733683,5208.547429,9198.281112,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Multifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 70 %,Positive : 50 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,None,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,glucophage|sotahexal|Diuver|cardura|milurit|atoris|hyzaar forte|Polocard,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Deceased,492|596|1009,No|No|No,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Never|Never|Never,Never|Never|Never,Yes|Yes|Yes,Yes|Yes|Yes,None|None|None,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,505.0|609.0|n/a,n/a|n/a|Cardiovascular Disorder,n/a|n/a|1035.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-01172,C3N-01172,No,b2,8,131N,CPT0095230003,Tumor,No,57,Female,Endometrioid carcinoma,G2 Moderately differentiated,2.5,165,80,29,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,1,Stage I,NA,0,CNV_L,No,20.34,MSI-H,MSI-H,553,Mutated,Mutated,WT,Mutated,Mutated,1.47E-19,8.06E-03,8.59E-04,9.18E-19,5.36E-18,0,7.82E-19,1.00E-19,0,0,3.70E-18,1.98E-03,2.91E-02,0,0,0,0,0,0,1.70E-02,1.14E-03,2.69E-19,0,2.25E-04,2.09E-21,0,5.78E-03,1.14E-19,0,5.12E-02,1.30E-02,6.40E-03,1.77E-18,9.11E-02,6.21E-02,0,6.28E-03,3.38E-20,6.28E-03,0,0,9.63E-03,2.72E-02,0,0.317302471,0,7.37E-02,0,0,0,2.35E-04,5.18E-02,0.149642383,2.74E-02,7.01E-02,1.82E-03,5.85E-02,0,0.134244772,1.54E-02,6.30E-02,35,67,92,0,0,0,95,99,0,0,0,0.83,NA,NA,-0.946346098,0.625565314,-1.265186151,1.570568446,-0.437061472,1.262791341,0.684931362,-0.874411812,0.500136872,-1.360868182,0.801243699,-2.136479043,2.218294711,0.800431099,1771.707456,3149.409592,4921.117048,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,0,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 60 %,Positive : 50 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Normal,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self-reported and Medical Record,Yes,Medical Record,Fragmin,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,555|709|961|1479,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,No|No|No|No,No|No|No|No,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,568.0|722.0|974.0|1492.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-01341,C3N-01341,No,b1,4,131N,CPT0095280003,Tumor,No,64,Female,Endometrioid carcinoma,G2 Moderately differentiated,5,168,95,33,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,9,Stage I,NA,9.78E-04,CNV_L,No,0,MSS,CNV_L,66,WT,Mutated,WT,Mutated,Mutated,8.64E-02,1.87E-02,6.33E-21,9.73E-19,6.85E-20,6.53E-19,7.82E-03,1.84E-19,2.75E-18,1.43E-02,4.32E-19,1.37E-02,7.24E-03,0,4.12E-03,1.53E-03,1.94E-19,4.93E-03,2.11E-18,2.49E-02,8.86E-03,8.82E-03,4.71E-04,1.02E-03,5.18E-19,2.79E-04,2.78E-03,7.02E-20,1.77E-18,1.13E-03,2.93E-02,8.05E-03,1.00E-19,7.09E-02,7.08E-03,0,2.20E-02,4.65E-03,2.67E-02,0,3.62E-03,0.10405177,4.75E-02,0,0.156197673,0,6.11E-02,0,0,0,0.123430266,9.08E-02,0,3.38E-03,0.263868097,2.58E-02,7.42E-02,3.96E-02,0,0,6.60E-03,27,32,0,0,0,0,0,0,0,0,0,0.66,NA,NA,0.478038492,0.102807066,0.239316893,3.78E-02,-0.283586538,0.603740038,8.86E-02,1.517526455,-9.23E-04,-0.251237819,0.331323806,0.163221202,-0.476046881,-0.253778156,3896.851759,4284.434815,8181.286574,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Multifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : 70 %,Positive : 50 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,Berotec|Tezeo|Cipronex|Fragmin,NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|Yes,Living|Living,343|343,No|No,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,No|No,2|2,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,353.0|353.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-01342,C3N-01342,No,b1,1,130C,CPT0088140003,Tumor,No,68,Female,Endometrioid carcinoma,G2 Moderately differentiated,4.6,164,95,35,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,11,Stage I,NA,0,CNV_L,No,0.03,MSS,CNV_L,59,WT,Mutated,Mutated,WT,WT,4.83E-02,2.29E-03,1.25E-19,0,8.32E-18,0,2.65E-02,0,9.06E-21,6.77E-04,0,1.06E-19,1.35E-03,2.31E-18,5.66E-21,0,2.19E-18,0,0,5.08E-03,9.75E-04,3.45E-03,1.07E-03,4.50E-03,3.48E-19,1.95E-18,2.58E-03,0,7.04E-18,8.99E-03,8.73E-03,8.96E-03,0,7.73E-02,3.45E-02,0,5.18E-03,6.51E-04,5.83E-03,0,0,0,4.73E-02,0,0.329401231,0,0,3.76E-02,0,0,0.110133339,7.10E-03,0,5.30E-02,0.249179947,0,2.93E-02,9.22E-02,0,0,4.49E-02,18,28,0,0,0,0,0,0,0,0,0,0.92,NA,NA,0.678806316,8.62E-02,-0.351367591,-0.266862729,-0.524670381,0.507325205,-0.994790741,0.174274834,-0.248611771,-0.28194513,-0.92349606,-0.96983554,1.933994758,0.47664936,2743.521331,2888.741889,5632.263219,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Multifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,Unknown,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Concor|Axtil|Ipress Long|Lecalpin|Captopril|Meloxicam,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,233|702|1063|1329,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,No|No|No|No,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,242.0|711.0|1072.0|1338.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-01344,C3N-01344,No,b2,8,130N,CPT0116340004,Tumor,No,80,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.5,150,107,47,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,10,Stage I,NA,4.89E-03,CNV_L,No,0.05,MSS,CNV_L,83,WT,Mutated,Mutated,Mutated,Mutated,6.35E-02,0,1.39E-18,2.55E-18,7.34E-18,0,3.44E-19,0,0,4.41E-18,0,0,0,0,6.07E-20,6.22E-19,8.47E-19,0,6.08E-19,2.54E-02,0,2.68E-03,4.99E-20,1.88E-05,4.28E-19,0,0,4.51E-19,7.65E-18,3.57E-04,2.69E-02,1.75E-03,0,7.77E-02,3.99E-19,9.22E-18,1.25E-05,1.67E-03,1.68E-03,0,0,1.88E-02,1.86E-02,0,0.184320429,0,7.32E-02,0,0,8.96E-03,5.74E-02,7.98E-02,0.106922609,1.56E-02,0.207896215,0,0.123534418,0,3.42E-02,7.49E-03,6.33E-02,36,24,0,16,0,0,0,0,0,0,0,0.65,Yes,No,1.010584357,0.958917619,-0.122092578,0.591618951,1.71548221,0.83661242,0.373454018,1.909639803,-0.407318649,0.19433427,0.53145782,-1.059607454,5.48E-02,1.491327304,2816.325831,3437.612906,6253.938737,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Multifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,oxycordil|diuresin|doxor|Clexane|kalipoz|fortrans|Cipronex|Potassium Chloride,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Deceased,424|654|1011|1011,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,448.0|678.0|1035.0|n/a,n/a|n/a|n/a|Respiratory Disease,n/a|n/a|n/a|1359.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-01525,C3N-01525,No,b1,4,129C,CPT0095880003,Tumor,No,77,Female,Endometrioid carcinoma,G2 Moderately differentiated,2,162,101,38.48,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,NA,6.56E-02,CNV_L,No,0.01,MSS,CNV_L,69,WT,Mutated,WT,Mutated,Mutated,0.113347672,0.138089515,7.26E-04,2.62E-02,0,8.19E-04,6.67E-02,3.50E-03,1.89E-02,1.32E-02,1.31E-19,3.48E-02,7.21E-03,0,1.22E-02,1.58E-02,0,1.90E-02,3.28E-20,5.74E-02,9.95E-03,1.08E-02,8.24E-03,9.63E-03,2.18E-02,2.38E-02,2.43E-02,2.24E-02,1.02E-19,4.41E-02,3.23E-02,1.70E-02,0,9.39E-03,4.00E-02,0,0.15660197,1.74E-02,0.174028141,6.38E-03,6.54E-02,6.88E-02,6.37E-02,0,0.338442194,0,1.62E-02,3.19E-02,0,1.67E-02,5.76E-03,0,3.46E-02,2.58E-02,0.159190306,0,6.96E-03,0,1.46E-02,0,0.145579711,22,38,0,0,0,0,0,0,0,0,0,0.24,NA,NA,0.968455041,0.116985024,0.586825416,-1.830026394,0.652835063,-0.358812128,1.262459572,1.604640792,-1.190027371,7.66E-03,1.127224327,2.7023317,-2.335287933,1.259273466,4455.437792,5641.829234,10097.26703,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 50 %,Positive : 30 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,Cytokeratin 7 - positive; Vimentin - positive;,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record,No,NA,NA,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,221|678,No|No,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,No|No,No|No,2|2,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,206.0|663.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-01526,C3N-01526,No,b1,2,129N,CPT0096010003,Tumor,No,66,Female,Other,G1 Well differentiated,1.5,163,120,45.17,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,9,Stage I,NA,1.44E-02,CNV_L,No,0.18,MSS,CNV_L,46,WT,Mutated,Mutated,WT,Mutated,4.79E-02,8.74E-03,2.18E-03,8.02E-18,0,1.50E-02,2.25E-02,8.64E-04,8.43E-04,1.38E-02,4.71E-18,1.20E-02,1.30E-02,1.30E-03,1.40E-04,3.54E-19,1.04E-03,7.72E-18,1.41E-17,4.30E-03,1.20E-02,1.28E-02,2.26E-03,8.05E-03,0,0,4.29E-03,3.69E-19,0,3.37E-02,7.09E-02,1.35E-02,3.66E-18,6.71E-02,5.27E-02,8.39E-03,2.05E-02,4.04E-18,2.05E-02,2.07E-02,0,2.84E-03,0.112389797,0,0.253080028,0.109388855,2.77E-03,0,0,0.140858162,0,4.29E-02,1.87E-02,6.00E-02,0.168718426,1.14E-02,0,0,4.26E-02,1.37E-02,0,11,18,12,0,0,0,0,0,0,0,0,0.75,NA,NA,-0.602082745,-0.32923972,0.335663418,-0.711535885,2.75E-02,0.266371451,-0.389968954,0.170962117,0.524567535,-0.974226972,-0.49249463,-0.756494607,-0.616693079,0.192387266,2830.616714,3480.307943,6310.924657,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 25 %,Positive : 45 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,Cytokeratin 7 - positive; Vimentin - positive;,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,No,NA,NA,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,206|663,No|No,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,No|No,2|2,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,206.0|663.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-01529,C3N-01529,No,b3,10,130C,CPT0097440003,Tumor,No,70,Female,Endometrioid carcinoma,G2 Moderately differentiated,2,161,77,29.71,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pNX,0,Stage I,NA,1.420667785,CNV_L,No,0.28,MSS,CNV_L,77,Mutated,WT,WT,Mutated,Mutated,6.98E-03,4.57E-03,0,0,2.18E-18,4.33E-03,0,0,2.53E-18,0,1.41E-18,6.17E-03,3.70E-04,8.82E-03,3.04E-19,1.52E-18,4.88E-19,0,0,1.98E-02,4.35E-18,1.53E-19,0,1.55E-02,2.79E-18,5.69E-18,2.68E-03,5.93E-19,0,5.64E-02,2.14E-02,2.04E-02,1.78E-18,4.84E-02,6.97E-02,0,1.34E-02,7.58E-19,1.34E-02,0,0,6.18E-03,4.62E-02,0,0.283628823,0,0,5.17E-03,0,3.31E-02,1.99E-02,2.27E-02,0.372928636,1.85E-03,0.191768164,0,6.01E-03,0,0,1.05E-02,0,15,39,0,0,0,0,17,0,0,0,0,0.8,NA,NA,-0.350698157,-1.787253484,0.375408379,-0.430807066,-0.988606273,-1.114672298,-1.083843371,-0.533844894,-0.259319555,-0.962619281,-1.003937609,-0.156204933,0.935634718,-1.285862678,1635.195132,2630.987183,4266.182316,Not Examined,Present,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 80 %,Positive : 90 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,CK7 - positive; Vimentin - positive;,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,2,12 Months,Yes,Living,27,Unknown,Unknown,Unknown,Unknown Tumor Status,Unknown,Unknown,Unknown,Unknown,Unknown,2,Unknown,Unknown,Unknown,n/a,Unknown,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a,n/a +C3N-01761,C3N-01761,No,b3,9,128N,CPT0116710003,Tumor,No,69,Female,Endometrioid carcinoma,G3 Poorly differentiated,4.5,162,72,27,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,12,Stage I,NA,2.000247062,CNV_L,No,22.53,MSI-H,MSI-H,624,WT,Mutated,WT,Mutated,WT,7.35E-02,9.41E-03,0,7.30E-18,1.35E-18,9.69E-19,3.91E-19,5.84E-20,2.64E-18,0,2.77E-18,2.02E-03,1.06E-02,0,9.71E-23,2.61E-03,4.00E-19,0,2.79E-18,2.06E-02,0,6.01E-04,4.02E-04,1.98E-04,3.67E-18,2.57E-17,0,0,6.10E-18,2.31E-02,1.01E-02,2.14E-02,0,0.148230371,0.133913,2.43E-18,6.41E-03,1.31E-03,7.71E-03,4.92E-02,0,0.108184728,0.122038116,0,0.221708232,0,0.118366604,0,0,0,5.94E-02,7.06E-03,4.36E-02,0.112296479,9.26E-02,0,0,0,8.40E-03,3.56E-03,5.36E-02,58,71,0,0,0,0,160,65,0,0,53,0.69,NA,NA,-0.594911418,1.032012483,-1.096912147,1.401428603,0.9708803,1.339458804,0.157450776,-0.785718131,1.358407618,-1.262712613,-9.68E-03,-0.903377582,0.971890694,-0.277578463,2707.093154,4003.392608,6710.485762,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Multifocal,0,0,1,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,1,Vimentine positive,NA,No,Lifelong non-drinker,Current smoker: Includes daily and non-daily smokers,Unknown,NA,20,NA,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Bisocard|milurit|effox long|diuresin|Fragmin|fortrans|kalipoz,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,244|839|979|1338,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|With Tumor|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Unknown|Never,Yes|Yes|Yes|Yes,No|No|No|No,1|1|1|1,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,Yes|Yes|Yes|Yes,New Primary Tumor|New Primary Tumor|New Primary Tumor|New Primary Tumor,Other: Kidney|Other: Kidney|Other: Kidney|Other: kidney,113.0|113.0|113.0|113.0,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,No|No|No|No,264.0|859.0|999.0|1358.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,113.0|113.0|113.0|113.0,Surgical Resection|Surgical Resection|Surgical Resection|Surgical Resection,R0: No Residual Tumor|R0: No Residual Tumor|R0: No Residual Tumor|R0: No Residual Tumor +C3N-01764,C3N-01764,No,b2,7,128C,CPT0181320003,Tumor,No,73,Female,Serous carcinoma,G3 Poorly differentiated,6,158,75,30,Present,<50% myometrial invasion,Seventh Edition (2010),pT2 (FIGO II),pN0,11,Stage II,NA,14.69558014,CNV_H,No,7.00E-02,MSS,CNV_H,64,Mutated,WT,WT,WT,Mutated,0.190726861,7.55E-02,1.67E-02,3.89E-03,1.96E-03,8.26E-18,3.27E-03,9.01E-03,1.74E-02,1.01E-02,5.00E-03,0,3.07E-02,0,1.14E-02,1.81E-18,0,8.66E-18,0,1.54E-02,3.38E-02,2.26E-02,2.21E-02,1.86E-03,3.26E-03,4.18E-03,1.05E-02,1.17E-20,1.18E-03,9.15E-03,2.42E-02,2.01E-02,9.29E-18,3.68E-02,0.25858588,7.24E-19,9.81E-02,5.24E-18,9.81E-02,7.31E-02,0,4.77E-02,0.108187785,0,0.114452992,3.87E-02,9.76E-02,0,0,0,5.85E-02,4.87E-03,4.11E-02,0.110210276,0.208625266,0,5.27E-02,0,1.94E-02,1.31E-02,1.18E-02,12,36,0,12,0,0,0,0,0,0,0,0.35,NA,NA,-0.286215717,0.380558766,-0.228724485,-0.203270537,2.099036814,8.69E-02,0.859025866,-0.737063438,5.87E-03,-0.429555029,0.62996958,-0.156939859,-2.61E-02,0.838316501,3940.012075,5240.349808,9180.361883,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Other,Isthmus of uterine corpus and cervical canal,Unifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : 10 %,Positive : 10 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,"Ki67 positive 50%, Vimentin positive, SMA negative, CD10 - positive/negative, Desmine- negative, Bcl-2 - negative, EMA - positive/negative, CK7 positive, CK8/18 - positive, CK19 - positive",NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Bisocard|Euthyrox|Fragmin|Fortrans|Natrium kalium|Kalipoz|Aldac,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,386|816|1201|1346,Yes|Yes|No|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,No|No|No|No,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,406.0|836.0|1221.0|1366.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-01765,C3N-01765,No,b1,4,130C,CPT0116940003,Tumor,No,58,Female,Endometrioid carcinoma,G2 Moderately differentiated,8,158,65,26,Present,=50% myometrial invasion,Seventh Edition (2010),pT3a (FIGO IIIA),pN1 (FIGO IIIC1),6,Stage III,NA,3.70E-03,CNV_L,No,14.61,MSI-H,MSI-H,771,WT,Mutated,Mutated,Mutated,Mutated,0.246545802,1.52E-02,6.86E-03,2.69E-18,0,1.69E-18,4.85E-02,1.17E-02,8.94E-02,0.114629111,4.22E-03,4.72E-03,1.16E-02,0,7.04E-03,0,2.69E-18,3.92E-03,0,1.81E-02,2.25E-03,1.11E-02,6.02E-03,2.77E-03,0,1.79E-18,5.35E-03,0,5.69E-18,1.66E-02,3.23E-02,2.10E-02,1.10E-18,8.01E-02,0.142359302,0,7.78E-02,1.96E-03,7.97E-02,1.97E-02,0,6.14E-02,0.134433128,0,0.261287416,2.98E-03,8.83E-02,4.97E-03,8.31E-02,0,4.02E-02,0,6.18E-02,9.54E-02,0.117614713,0,0,2.87E-02,0,0,0,95,176,0,0,0,0,160,0,72,0,123,0.4,NA,NA,0.138864277,0.316001016,0.692017961,0.825944117,0.30805158,-3.20E-02,-0.799914545,-0.424941507,-0.125753229,0.750546401,-0.955156205,0.173068789,-0.561494049,-5.88E-02,5013.704003,5217.161207,10230.86521,Not Examined,Present,Cannot be assessed,NA,Caucasian,Poland,Fundus,NA,Unifocal,IHC staining not done,0,2,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,metronidazol|Cipronex|Fragmin|kalipoz,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,259|484|988|1352,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,No|No|No|No,No|No|No|No,3|3|3|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,271.0|496.0|1000.0|1364.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-01766,C3N-01766,No,b1,2,128C,CPT0226810003,Tumor,No,63,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.5,165,108,39,Not identified,NA,Seventh Edition (2010),pT1b (FIGO IB),pNX,0,Stage I,NA,0,CNV_L,No,0.01,MSS,CNV_L,52,WT,Mutated,WT,Mutated,Mutated,9.03E-02,0,0,0,8.36E-19,0,0,2.13E-03,0,8.21E-03,0,0,2.16E-02,2.59E-19,3.61E-03,2.73E-02,2.60E-19,0.143591591,0,0.125117983,3.23E-02,2.27E-02,1.35E-02,1.76E-03,4.41E-18,4.62E-03,0,3.30E-03,1.29E-17,3.01E-03,2.17E-02,0,0,4.92E-02,9.14E-02,0,3.04E-02,9.03E-02,0.12067751,0,0,5.74E-02,3.91E-02,0,0.136205481,0,2.06E-02,0,0,3.28E-02,4.07E-02,6.15E-02,8.77E-03,4.84E-03,0.360359682,4.23E-02,2.23E-02,4.40E-02,6.55E-03,1.93E-02,0.103249658,23,24,0,0,0,0,0,0,0,0,0,0.33,Yes,No,-0.212399685,-0.179274308,0.514966703,-0.1912367,-0.549840059,-1.46E-02,0.326598797,0.865885353,-1.060837629,9.72E-02,0.406557973,0.163027314,-0.82872889,0.756589656,5172.775259,4941.366454,10114.14171,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Euthyrox|Nebilet|Metformax|Gensulin R|Gensulin N|Jardiance|Pramolan|Valsacor|Tertensif SR|Nebilet|Dulsevia,NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|Yes,Living|Living,372|520,No|No,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,Yes|Yes,3|2,No|No,Complete Remission|Complete Remission,Complete Remission|Unknown,n/a|n/a,No|Unknown,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,372.0|520.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-01830,C3N-01830,No,b3,12,128N,CPT0097300003,Tumor,No,73,Female,Endometrioid carcinoma,G2 Moderately differentiated,1.5,163,72,27.1,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,5,Stage I,NA,0.121195139,CNV_L,No,0.11,MSS,CNV_L,67,WT,Mutated,Mutated,Mutated,WT,1.16E-18,2.43E-03,7.51E-20,0,0,1.91E-18,1.98E-18,9.54E-03,1.69E-02,2.20E-02,0,0,6.54E-03,1.87E-18,4.08E-21,1.19E-03,8.84E-19,5.68E-02,1.48E-18,2.47E-02,0,0,7.39E-04,4.06E-03,1.48E-19,2.26E-17,3.67E-03,1.37E-18,0,0,2.56E-02,1.10E-02,8.69E-19,2.09E-02,5.22E-02,0,1.56E-02,2.90E-02,4.46E-02,0,0,8.43E-02,9.39E-02,0,0.191293251,0,0,2.43E-02,0.121978416,0,4.96E-02,0,6.59E-02,3.86E-02,0.156815348,0,2.17E-02,7.53E-02,0,0,7.63E-02,28,34,0,0,0,0,0,0,0,0,0,0.17,NA,NA,1.144298628,-0.244991698,0.277131716,0.359918433,-0.270113667,0.386533568,-0.764118355,7.87E-02,-0.377960293,0.214227381,-0.785101313,5.41E-02,-0.961078663,1.142328869,3244.306649,2922.030539,6166.337188,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 90 %,Positive : 90 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,CK7 - positive; Vimentin - positive;,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,228|716,Yes|Yes,Yes|Yes,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,No|No,Unknown|Unknown,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,192.0|680.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-01843,C3N-01843,No,b3,9,127N,CPT0098270003,Tumor,No,68,Female,Endometrioid carcinoma,G2 Moderately differentiated,1.4,164,64,23.8,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN1 (FIGO IIIC1),10,Stage III,NA,0.282470823,CNV_L,No,18,MSI-H,MSI-H,681,Mutated,Mutated,WT,Mutated,Mutated,0.223526843,3.01E-02,1.31E-02,0,4.93E-18,5.83E-18,1.80E-02,3.31E-03,1.33E-02,4.66E-02,0,8.84E-03,2.50E-02,1.01E-18,1.21E-02,0,8.36E-19,9.35E-18,3.42E-18,2.66E-02,2.73E-02,2.74E-02,6.44E-03,5.67E-03,1.34E-19,3.79E-18,5.54E-03,5.42E-19,4.95E-18,3.21E-02,7.54E-02,8.41E-03,0,4.49E-02,0.247032703,8.98E-19,5.90E-02,4.67E-18,5.90E-02,0,0,2.72E-02,0.216393599,0,0.128096267,0,8.38E-02,0,0,0,6.90E-02,3.29E-02,4.84E-02,9.27E-02,0.248276041,1.97E-02,0,3.36E-02,0,0,0,43,13,216,0,0,0,0,152,0,0,71,0.51,NA,NA,4.43E-02,0.144663114,-7.23E-02,5.24E-02,-0.547351059,0.534132119,1.47E-02,-0.311919732,0.56525262,-2.62E-02,2.85E-02,0.137575459,0.701965702,0.115626401,3834.743959,5059.640457,8894.384416,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,1,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 20 %,Positive : 20 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,CK7 - positive; Vimentin - patchy positive;,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Current smoker: Includes daily and non-daily smokers,43,NA,10,12.5,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,No,NA,NA,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,201|738,Yes|Yes,No|No,No|No,Tumor Free|With Tumor,Never|Never,Never|Never,Never|Never,No|No,No|No,2|2,No|No,Complete Remission|Complete Remission,Complete Remission|Persistent Disease,n/a|n/a,No|Yes,n/a|Distant Metastasis,n/a|Other: Peritoneal carcinomatosis,n/a|706.0,n/a|No,n/a|No,n/a|Yes,n/a|No,165.0|702.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-01847,C3N-01847,No,b1,3,130C,CPT0098920003,Tumor,No,57,Female,Endometrioid carcinoma,G1 Well differentiated,1.4,163,116,43.66,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,NA,3.70E-03,CNV_L,No,0.03,MSS,CNV_L,84,WT,Mutated,WT,Mutated,Mutated,7.60E-02,7.94E-03,8.91E-04,0,0,0,2.50E-02,2.35E-04,1.02E-19,1.14E-02,3.11E-19,1.48E-02,2.61E-02,0,2.80E-03,1.53E-02,4.03E-03,1.17E-18,3.06E-18,4.48E-02,5.96E-03,4.44E-03,5.40E-03,4.90E-04,2.19E-18,4.98E-03,3.19E-03,4.29E-04,0,6.23E-04,4.76E-03,5.31E-04,3.54E-18,4.36E-02,7.69E-02,0,1.78E-02,7.63E-03,2.54E-02,2.28E-03,0,4.47E-03,3.78E-02,0,0.280090609,0,1.52E-02,4.91E-02,0,2.66E-02,0,3.17E-04,2.13E-03,3.85E-02,0.309974614,8.53E-02,1.07E-02,7.10E-02,0,0,6.66E-02,26,33,0,0,0,0,20,0,0,0,0,0.24,NA,NA,-0.203958163,0.354768534,0.697546386,0.636621984,-0.105211027,0.664941363,0.597701371,1.192832327,-0.627929428,-0.384998838,0.566847748,0.695395794,-0.358632918,1.260857813,3847.422934,4238.491726,8085.91466,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 80 %,Positive : 80 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,CK7 - positive; Vimentin - positive;,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,2,12 Months,Yes,Living,32,No,No,No,Tumor Free,Never,Never,Never,Yes,No,Unknown,No,Complete Remission,Complete Remission,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,11,n/a,n/a,n/a,n/a,n/a +C3N-01848,C3N-01848,No,b3,12,131C,CPT0099050003,Tumor,No,68,Female,Endometrioid carcinoma,G2 Moderately differentiated,1.3,160,77,30.08,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pNX,0,Stage I,NA,0.254035118,CNV_L,No,3.44,MSS,CNV_L,320,WT,Mutated,WT,Mutated,WT,7.70E-02,1.36E-02,0,2.58E-18,0,2.32E-18,8.62E-03,4.51E-19,5.40E-19,0,5.49E-19,2.80E-19,5.58E-03,0,2.69E-03,2.80E-02,1.23E-18,1.04E-02,0,5.98E-02,1.12E-02,1.14E-02,8.93E-03,3.32E-03,0,2.41E-18,4.92E-03,0,7.35E-20,2.34E-02,7.03E-03,2.29E-02,0,3.13E-02,0.131746335,0,2.05E-02,1.92E-02,3.98E-02,1.53E-02,0,0.138733616,8.36E-02,0,0.263437163,0,2.35E-02,1.45E-02,0,1.72E-02,0,0,6.49E-02,5.09E-02,0.285224525,1.38E-02,1.10E-02,0,4.72E-03,8.52E-04,1.25E-02,8,35,113,0,0,0,0,50,0,0,27,0.2,NA,NA,1.139570918,-0.531494785,-0.962600331,2.147275985,-9.99E-02,-0.502091483,-0.188633044,-0.891483434,-0.156879223,0.417927495,-6.95E-02,0.412675045,-0.163980249,-0.799125931,4904.734919,4328.776721,9233.51164,Not Examined,Present,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 15 %,Positive : 15 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,2,CK7 - positive; Vimentin - positive;,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,No,NA,NA,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,193|709,Yes|Yes,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,No|No,2|2,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,172.0|688.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-01871,C3N-01871,No,b4,13,130C,CPT0117010004,Tumor,No,77,Female,Endometrioid carcinoma,G2 Moderately differentiated,2.4,149,80,36,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,NA,1.09E-03,CNV_L,No,10.85,MSI-H,MSI-H,683,WT,Mutated,WT,Mutated,Mutated,6.25E-02,3.82E-03,0,9.99E-19,0,7.50E-19,1.12E-02,0,0,1.26E-02,0,8.23E-03,8.10E-03,0,1.39E-02,2.33E-19,1.07E-19,0,2.79E-18,2.14E-02,3.31E-03,7.85E-03,2.88E-03,3.68E-03,4.70E-18,0,1.15E-03,7.57E-19,2.61E-18,2.08E-03,2.21E-02,7.01E-03,2.44E-18,3.25E-02,0.118236283,8.15E-19,1.65E-02,2.14E-04,1.67E-02,3.86E-02,0,0.100928794,0.135339536,0,0.122688657,5.80E-02,9.27E-02,0,9.91E-03,0,1.77E-02,0,3.71E-02,4.53E-02,0.302402469,1.76E-02,0,0,9.55E-03,2.79E-03,9.40E-03,0,47,294,0,0,0,0,91,0,0,74,0.27,NA,NA,0.302900335,0.516058367,0.292252452,1.083780096,-1.083293559,0.476643996,-0.47464658,0.42683152,-6.25E-02,-0.164209424,-0.388869335,-0.35724918,0.36279121,1.213801812,3831.676349,4112.023105,7943.699453,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Unifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Yes,Self Report|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,co-valsacor|kalipoz|Fragmin|Citrafleet|Iporel,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,243|684|963|1412,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,No|No|No|No,3|3|3|3,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,253.0|694.0|973.0|1422.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-01873,C3N-01873,No,b4,16,127N,CPT0117230003,Tumor,No,71,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.5,164,81,30,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,3,Stage I,NA,1.38E-02,CNV_L,No,0.03,MSS,CNV_L,59,WT,Mutated,Mutated,WT,WT,8.33E-02,1.05E-02,1.14E-18,0,5.14E-18,7.84E-03,1.99E-02,0,1.58E-19,0,0,4.95E-03,0,0,0,4.90E-03,4.86E-19,1.28E-18,0,3.43E-03,7.45E-03,1.37E-02,3.29E-03,6.46E-03,0,9.67E-19,4.38E-03,0,7.33E-18,4.05E-02,2.96E-02,1.70E-02,4.03E-18,1.53E-02,2.32E-02,2.23E-03,1.63E-02,2.45E-03,1.87E-02,0,0,0.173787939,0.114182112,0,0.116560122,0,4.27E-02,3.14E-02,0,3.82E-03,4.17E-02,4.45E-02,0.156313502,4.00E-02,0.140850526,0,0,0,8.17E-02,0,1.26E-02,15,18,0,0,0,0,16,0,0,0,0,0.75,NA,NA,0.106481953,0.43067387,-0.9722897,1.06846311,-0.216816855,0.300596224,0.470600851,0.290423913,0.552485217,-0.815837183,0.521103887,-0.243989694,0.206061519,1.169256133,2190.410018,4249.679464,6440.089482,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self-reported and Medical Record|Self-reported and Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Amlopin|Euthyrox|Metocard|Lorista H|Fragmin,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,361|606|959|1325,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,No|No|No|No,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,375.0|620.0|973.0|1339.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-01874,C3N-01874,No,b4,16,129C,CPT0117300003,Tumor,No,84,Female,Endometrioid carcinoma,G1 Well differentiated,2.5,158,76,30,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,NA,1.800134566,CNV_L,No,0.12,MSS,CNV_L,58,WT,Mutated,Mutated,Mutated,Mutated,1.52E-02,1.17E-18,2.86E-18,3.41E-18,1.45E-18,0,1.56E-17,0,6.10E-18,1.23E-17,1.05E-18,1.33E-18,0,1.19E-18,1.00E-19,0,0,1.82E-17,0,0,0,7.99E-20,1.07E-19,1.14E-02,0,1.96E-17,3.50E-03,0,6.22E-17,3.22E-02,1.59E-02,1.58E-02,2.29E-18,6.37E-02,2.03E-19,4.50E-19,7.62E-03,9.13E-18,7.62E-03,0,0,7.05E-02,6.17E-02,0,0.142400803,0,9.16E-02,3.51E-02,0,0,2.84E-02,2.52E-02,6.77E-02,0,0.340888389,0,5.24E-02,8.43E-02,0,0,0,13,17,0,0,0,0,24,0,0,0,0,0.92,Yes,No,0.244211136,-1.414841471,-0.925858253,-0.153620361,-0.502347154,-1.089310841,-2.733835426,-0.859543811,-0.500990905,-0.608425221,-2.485675847,-1.325090731,1.86172286,-0.201595836,1021.173704,1322.951831,2344.125535,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Insulatard|Mixtard|Fragmin|nitrendypina|Tarcefoksym|Potassium Chloride,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Deceased,398|817|1027|1027,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,3|3|3|3,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,410.0|829.0|1039.0|n/a,n/a|n/a|n/a|Respiratory Disease,n/a|n/a|n/a|1267.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-01875,C3N-01875,No,b1,2,127C,CPT0117370004,Tumor,No,66,Female,Endometrioid carcinoma,G1 Well differentiated,3.5,165,67,24,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,NA,4.90E-02,CNV_L,No,13.51,MSI-H,MSI-H,432,WT,Mutated,WT,Mutated,Mutated,9.06E-02,4.35E-03,3.23E-19,9.90E-18,0,0,0,0,0,8.78E-18,1.24E-18,1.64E-02,6.04E-03,4.24E-18,0,3.92E-18,6.19E-18,1.67E-17,4.29E-18,2.73E-02,4.62E-19,1.29E-03,5.24E-03,4.99E-03,1.80E-19,2.29E-17,2.03E-03,1.90E-18,3.49E-19,1.98E-02,1.10E-02,4.26E-03,1.19E-18,8.04E-02,3.62E-02,7.16E-19,6.23E-03,1.03E-17,6.23E-03,0,0,1.24E-02,0.157910704,0,0.246611062,0,6.92E-02,2.93E-04,0,0,5.50E-02,0.100858138,0,2.02E-02,0.241064221,3.03E-02,3.34E-02,0,6.70E-03,4.79E-03,2.13E-02,5,45,262,0,0,0,0,0,0,0,0,0.82,NA,NA,-1.363689812,-4.89E-02,-1.529508912,-0.553215043,-0.634025083,0.390767965,-0.119760407,-0.111178363,0.344065615,-1.171730701,-7.18E-02,-0.597194535,1.768138045,0.172848677,2183.985888,3574.391886,5758.377774,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Other,left side of uterine cavity,Unifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Self-reported and Medical Record,Yes,Medical Record,citrafleet,NA,NA,NA,NA,Yes,1,12 Months,Yes,Living,48,No,No,No,Tumor Free,Never,Never,Never,No,No,2,No,Complete Remission,Complete Remission,n/a,Unknown,n/a,n/a,n/a,n/a,n/a,n/a,n/a,66,n/a,n/a,n/a,n/a,n/a +C3N-01876,C3N-01876,No,b4,15,128N,CPT0117440003,Tumor,No,65,Female,Endometrioid carcinoma,G2 Moderately differentiated,6,160,76,29,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,11,Stage I,NA,0,CNV_L,No,30.86,MSI-H,MSI-H,1200,WT,Mutated,Mutated,Mutated,WT,0.121096139,2.94E-03,0,4.68E-18,0,1.44E-18,0,3.85E-03,0,0,1.70E-18,0,9.28E-03,0,4.75E-03,1.14E-18,0,3.16E-18,4.08E-18,0,2.45E-03,8.54E-03,3.41E-03,8.83E-03,0,5.97E-18,0,0,2.59E-17,2.46E-02,5.26E-02,2.27E-02,7.02E-03,0.145036196,0.153952945,3.74E-18,1.26E-02,3.12E-18,1.26E-02,1.21E-02,0,8.37E-02,0.113594656,0,0.170929985,2.97E-02,0.129824121,0,3.77E-02,0,4.75E-02,0,0.122970951,7.81E-02,0.167485468,3.59E-03,0,2.75E-03,0,0,0,4,128,256,0,0,0,257,110,119,0,0,0.66,NA,NA,0.559073275,0.680713095,-0.752155232,0.647809148,-0.702791641,0.933029185,-0.500273297,0.931540716,1.020084157,-0.395834595,-0.375792936,-0.910458356,0.450531888,0.578826112,2723.908546,4237.496025,6961.404571,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,0,0,3,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Lokren|Vanatex|Lexotan|Acard|fragmin|Fortrans,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,392|683|1071|1509,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,No|No|No|No,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,409.0|700.0|1088.0|1526.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-01877,C3N-01877,No,b2,8,127N,CPT0117510003,Tumor,No,73,Female,Endometrioid carcinoma,G2 Moderately differentiated,8,163,100,37,Present,=50% myometrial invasion,Seventh Edition (2010),pT3b (FIGO IIIB),pN2 (FIGO IIIC2),17,Stage III,NA,5.61E-03,CNV_L,No,11.86,MSI-H,MSI-H,726,WT,Mutated,WT,Mutated,Mutated,0.177404359,3.49E-02,7.77E-04,0,4.02E-18,5.17E-19,6.30E-02,0,1.63E-02,1.90E-02,1.99E-18,3.61E-03,1.62E-02,5.18E-19,7.60E-03,2.04E-02,1.97E-03,4.46E-02,2.95E-18,6.93E-02,1.09E-02,9.92E-03,1.08E-02,1.00E-02,5.72E-04,3.74E-03,7.22E-03,6.81E-20,1.08E-19,3.98E-02,2.16E-02,2.29E-02,6.13E-20,6.77E-02,4.62E-02,6.13E-03,5.70E-02,3.42E-02,9.11E-02,0,2.63E-02,0.114976296,5.65E-02,0,0.298018221,0,5.30E-02,0,0,4.07E-03,8.95E-03,8.79E-03,4.93E-02,7.36E-02,0.172018072,6.28E-02,0,6.47E-02,0,0,6.91E-03,10,145,147,0,0,0,127,114,0,0,0,0.17,NA,NA,-3.17E-02,1.77E-02,3.37E-02,-0.659912822,-1.29076585,-0.103905023,7.33E-02,-0.816857239,-0.29263442,0.376151556,-0.11418628,0.238528748,-0.47811667,0.441443599,4764.458571,5173.015659,9937.47423,Not Examined,Not identified,Margin(s) involved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,4,4,5,1,1,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,NA,NA,No,Lifelong non-drinker,Current smoker: Includes daily and non-daily smokers,Unknown,NA,20,NA,Yes,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Atrovent|Flutixon|Enarenal|Zafiron|fragmin|Cipronex|Metronidazol|Fortrans,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Deceased,397|678|678,No|No|No,Yes|Yes|Yes,No|No|No,With Tumor|With Tumor|With Tumor,Never|Never|Never,Never|Never|Never,Never|Never|Never,Yes|Yes|Yes,No|No|No,3|3|3,No|No|No,Persistent Disease|Persistent Disease|Patient Deceased,Persistent Disease|Persistent Disease|Patient Deceased,n/a|n/a|n/a,Yes|Yes|No,Distant Metastasis|Distant Metastasis|n/a,Other: vaginal cuff and paraortic lymph nodes|Other: rectum and paraortal lymph nodes|n/a,195.0|604.0|n/a,No|No|n/a,No|No|n/a,Yes|Yes|n/a,No|No|n/a,412.0|693.0|n/a,n/a|n/a|Uterine Corpus Cancer,n/a|n/a|912.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-01878,C3N-01878,No,b2,5,129C,CPT0117560003,Tumor,No,59,Female,Endometrioid carcinoma,G2 Moderately differentiated,10.5,170,106,36,Present,=50% myometrial invasion,Seventh Edition (2010),pT2 (FIGO II),pN2 (FIGO IIIC2),6,Stage II,NA,0.6351284,CNV_L,No,20.15,MSI-H,MSI-H,837,WT,Mutated,WT,Mutated,Mutated,0.199708337,2.28E-02,8.86E-03,0,1.19E-18,0,5.52E-02,8.07E-21,3.10E-04,4.05E-02,0,4.42E-02,1.95E-02,1.98E-18,2.88E-02,4.75E-19,1.20E-18,0,1.93E-18,7.79E-03,2.89E-02,2.82E-02,5.85E-03,5.89E-04,0,2.20E-03,3.47E-18,0,2.38E-18,1.85E-02,6.86E-02,1.76E-02,5.34E-18,4.04E-02,0.151555088,3.31E-02,5.57E-02,2.37E-19,5.57E-02,7.27E-03,0,1.94E-02,0.125281925,0,0.214293137,0,3.11E-02,2.34E-02,0,0,8.62E-02,1.21E-02,0.160409928,4.09E-02,0.244346272,1.44E-02,0,0,1.61E-02,4.78E-03,0,25,74,285,0,0,0,0,203,0,0,0,0.55,Yes,No,-0.181577593,1.397289792,0.635311483,1.162459583,-0.616480681,0.98083274,0.669498781,0.829350251,0.762932699,0.239677216,0.519901832,1.391960865,0.982448781,-0.881420623,5148.669003,5726.274774,10874.94378,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Unifocal,IHC staining not done,1,24,IHC staining not done,1,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,"ER(+), PR(+), p53(-), panCK, CK7, p16, CK5/6",NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self-reported and Medical Record|Self-reported and Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record,Bisopromerck|metformax,NA,NA,NA,NA,Yes,1,12 Months,Yes,Living,162,Yes,Yes,No,Tumor Free,Never,Never,Never,Yes,Yes,2,No,Complete Remission,Complete Remission,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,188,n/a,n/a,n/a,n/a,n/a +C3N-01879,C3N-01879,No,b2,8,127C,CPT0226860003,Tumor,No,67,Female,Endometrioid carcinoma,G1 Well differentiated,4,164,104,38,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,7,Stage I,NA,0,CNV_L,Yes,7.00E-02,MSS,POLE,2239,Mutated,Mutated,WT,Mutated,Mutated,0.137455678,4.02E-02,1.41E-02,3.66E-18,9.86E-20,0,4.28E-02,0,7.38E-03,6.30E-02,9.25E-18,7.35E-03,1.82E-02,0,8.02E-03,1.48E-03,0,9.46E-18,0,1.38E-02,3.08E-02,2.14E-02,1.09E-02,6.56E-06,3.93E-03,1.22E-02,1.30E-02,4.87E-03,3.27E-18,1.98E-02,6.48E-02,2.11E-02,0,3.09E-02,4.58E-02,2.86E-02,6.91E-02,7.39E-04,6.98E-02,1.35E-02,0,2.50E-02,7.75E-02,0,0.227319109,9.34E-02,6.00E-02,0,0,0,1.57E-02,0,0.173488158,0.106049337,0.129079703,7.92E-03,0,5.35E-03,0,0,6.57E-02,169,126,0,0,492,1440,0,0,0,0,0,0.55,NA,NA,-0.152512497,1.429161576,1.091894133,3.201166668,-6.38E-02,1.536337968,1.483652505,-0.92167649,0.836126569,-0.909618405,1.498413183,0.17598968,0.142423981,1.59541048,4156.428126,5829.00019,9985.428316,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self Report|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Euthyrox|Atoris|Aldan,NA,NA,NA,NA,Yes,1,12 Months,Yes,Living,489,No,No,No,Tumor Free,Never,Never,Never,Yes,No,2,No,Complete Remission,Unknown,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,489,n/a,n/a,n/a,n/a,n/a +C3N-01880,C3N-01880,No,b4,14,131N,CPT0244510003,Tumor,No,68,Female,Endometrioid carcinoma,G2 Moderately differentiated,6,157,76,30,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,13,Stage I,NA,5.74E-03,CNV_L,No,2.46,MSS,CNV_L,169,WT,Mutated,WT,WT,Mutated,0.174442329,3.33E-02,1.16E-02,5.53E-18,0,1.28E-18,3.50E-02,9.48E-04,1.97E-02,2.47E-02,4.55E-18,5.53E-03,1.97E-02,6.66E-03,1.89E-02,1.03E-02,0,3.13E-18,0,5.43E-02,3.95E-02,2.55E-02,2.40E-02,1.30E-02,1.30E-19,3.38E-18,1.06E-02,0,0,1.46E-02,3.16E-02,1.82E-02,0,3.81E-02,3.68E-02,2.32E-02,8.29E-02,5.16E-03,8.81E-02,6.19E-03,0,6.65E-02,6.73E-02,0,0.242474543,0,3.09E-02,0,1.56E-02,0,1.82E-02,0,9.68E-02,0.105584982,0.275675943,5.71E-03,0,6.92E-02,0,0,0,26,43,0,0,0,0,55,0,0,0,0,0.56,NA,NA,0.70910867,-1.400986602,2.046975559,2.73E-02,-2.65E-03,-1.50845047,0.203122598,3.34E-02,-0.623237411,-0.769186317,0.191999416,0.755493383,-0.607070106,-0.259883536,4534.7251,5118.019807,9652.744907,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Unifocal,0,0,5,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record,Yes,Medical Record|Medical Record,Imovate|Vit B2,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,411|745|1074|1531,No|No|No|Yes,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,No|No|No|No,No|No|No|No,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,411.0|745.0|1074.0|1531.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-02012,C3N-02012,No,b1,4,130N,CPT0115470003,Tumor,No,69,Female,Endometrioid carcinoma,G2 Moderately differentiated,3,173,126,42.11,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,30,Stage I,White,0,CNV_L,No,0.13,MSS,CNV_L,39,WT,Mutated,Mutated,Mutated,WT,0.10837779,2.33E-02,0,0,0,0,2.77E-02,0,3.69E-19,1.66E-02,4.50E-19,1.87E-19,6.36E-03,0,3.77E-03,5.12E-03,0,0,5.32E-19,3.07E-19,1.03E-02,1.17E-02,5.31E-03,4.45E-03,0,0,4.26E-03,4.59E-19,0,2.99E-02,2.66E-02,1.32E-02,0,9.35E-02,0.104035137,3.39E-03,2.79E-02,2.56E-03,3.04E-02,2.38E-03,6.60E-03,0.100506775,2.23E-02,0,0.193876697,0,0.114171638,1.65E-02,8.98E-04,0,0.103761073,3.46E-02,6.48E-02,2.79E-02,0.182560871,8.04E-03,2.33E-02,0,4.64E-02,3.03E-03,4.85E-02,9,24,0,0,0,0,0,0,0,0,0,0.31,NA,NA,-0.530721444,1.171436913,-0.331317798,0.100828289,0.158560762,0.533353021,1.460192614,-0.436046742,0.655455465,-0.683019213,1.427569954,-0.314388587,0.463815547,-9.64E-02,3396.330521,4983.009654,8379.340175,Atypical and/or suspicious,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,white,United States,Other,Involves anterior and posterior,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,1,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,aspirin|lipitor|temovate|docusate|hydroxychloroquine|levothyroxine|metaprolol,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,398|762|1126|1490,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Unknown|Unknown|Unknown|Unknown,Unknown|Unknown|Unknown|Unknown,Yes|Yes|Yes|Yes,No|No|No|No,1|1|1|1,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,378.0|742.0|1106.0|1470.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-02027,C3N-02027,No,b2,7,127N,CPT0133400008,Tumor,No,55,Female,Endometrioid carcinoma,G3 Poorly differentiated,1.5,161,62,23.92,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,10,Stage I,NA,0.836262984,CNV_L,No,29.19,MSI-H,MSI-H,1588,Mutated,Mutated,WT,Mutated,Mutated,0.13465926,1.32E-02,6.68E-03,1.39E-18,0,2.20E-18,1.18E-02,1.20E-02,0,1.22E-03,1.57E-18,3.73E-03,2.35E-02,3.44E-19,3.51E-03,0,0,0,0,2.73E-03,2.85E-02,2.99E-02,6.40E-03,3.08E-03,0,0,2.52E-03,0,4.50E-18,1.53E-02,5.43E-02,3.77E-03,0,9.58E-02,0.191302974,4.18E-18,3.22E-02,0,3.22E-02,1.70E-02,0,2.71E-02,4.57E-02,0,0.236501993,3.10E-02,5.83E-02,0,1.41E-02,0,4.11E-02,2.91E-03,0.120051349,0.191009379,0.194287952,0,0,9.09E-03,0,0,1.19E-02,281,255,0,0,0,0,406,263,0,0,0,0.22,NA,NA,-1.620645881,1.030313371,-1.867447847,1.518661251,-1.110265741,0.865446114,0.804264842,-0.359433287,1.926234681,0.573562232,0.55489661,-1.086838292,4.40E-02,-0.319440063,3784.602642,4222.588922,8007.191565,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 80 %,Negative,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,Unknown,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,CK7 - positive; Vimentin - patchy positive; ER - 80% (+++); PR - negative;,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,498|874,Yes|Yes,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,No|No,No|No,Unknown|Unknown,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,440.0|816.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-02028,C3N-02028,No,b1,3,128N,CPT0133600003,Tumor,No,68,Female,Endometrioid carcinoma,G3 Poorly differentiated,1.3,160,103,40.23,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,10,Stage I,NA,0.94592098,CNV_L,No,16.98,MSI-H,MSI-H,854,WT,Mutated,WT,Mutated,Mutated,0.137349875,6.08E-03,1.45E-02,8.40E-19,2.55E-18,0,1.54E-03,1.23E-02,4.24E-02,4.63E-02,0,0,3.00E-02,1.67E-18,1.97E-02,2.67E-02,0,8.72E-02,3.34E-18,0.171591381,1.98E-02,1.96E-02,5.55E-03,3.66E-03,3.12E-18,0,7.02E-03,3.97E-19,5.56E-18,8.39E-19,4.58E-02,9.70E-03,0,6.20E-03,0.29710689,2.24E-19,6.11E-02,6.08E-02,0.121915215,1.82E-02,0,2.64E-02,0.155186169,0,0.173452888,6.00E-02,6.69E-02,0,1.17E-02,0,2.01E-02,0,0.110151944,0.100243419,0.165907003,0,0,0,6.10E-02,1.98E-02,1.10E-02,0,51,377,0,0,0,0,109,0,0,93,0.16,NA,NA,0.650007282,-8.93E-02,-0.188888952,2.38E-02,-8.43E-02,0.377410318,0.783005019,0.421413623,0.896518726,0.700052389,0.673144646,1.335396533,-1.52790344,0.469251306,6118.023607,5850.288699,11968.31231,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 60 %,Positive : 20 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,CK7 - positive; Vimentin - patchy positive; ER - 60%; PR - 20%;,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-02030,C3N-02030,No,b1,4,127C,CPT0133770008,Tumor,No,62,Female,Endometrioid carcinoma,G2 Moderately differentiated,1.4,163,131,49.31,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pNX,0,Stage I,NA,0,CNV_L,No,12.53,MSI-H,MSI-H,509,WT,Mutated,Mutated,Mutated,WT,2.01E-18,1.47E-19,0,7.53E-18,2.96E-18,0,0,2.19E-19,3.11E-19,5.32E-18,0,0,5.55E-03,0,7.17E-19,1.19E-18,1.21E-18,2.32E-02,0,1.48E-04,0,6.33E-19,0,2.21E-02,0,1.63E-18,6.42E-03,0,0,4.27E-02,3.72E-03,1.38E-02,0,3.09E-02,0.106855103,2.14E-19,1.47E-02,1.37E-02,2.85E-02,1.84E-02,0,0.100547164,5.72E-03,0,0.174504876,0,0,6.92E-02,0,9.15E-02,0,0,0.326854429,0,8.54E-02,0,3.66E-02,0,9.12E-02,0,0,24,64,187,0,0,0,0,54,0,0,50,0.66,NA,NA,1.156356082,1.50100684,0.652103028,1.076495637,-2.130746153,1.268860898,0.252439451,0.981173532,0.283160486,1.172658794,0.448894477,1.278679606,-0.978229726,1.82680905,3771.888795,2333.565376,6105.454171,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,0,0,cM0,R0: No residual tumor,Positive : 70 %,Positive : 60 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,CK7 - positive; Vimentin - patchy positive; ER - 70%; PR - 60%,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,270|808,Yes|Yes,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,No|No,Unknown|Unknown,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,284.0|822.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-02061,C3N-02061,No,b1,2,129C,CPT0134310008,Tumor,No,67,Female,Endometrioid carcinoma,G2 Moderately differentiated,1.7,150,92,40.89,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,10,Stage I,NA,6.67E-03,CNV_L,No,9.86,MSI-H,MSI-H,461,WT,Mutated,WT,WT,Mutated,0.157836188,1.89E-02,1.43E-02,0,1.80E-19,2.43E-18,2.64E-03,9.82E-03,2.36E-02,1.44E-02,0,0,2.41E-02,1.64E-21,7.12E-03,1.83E-03,7.89E-19,8.53E-02,0,9.94E-02,2.51E-02,1.67E-02,2.32E-02,6.63E-03,5.50E-20,6.31E-19,1.09E-03,5.16E-19,1.74E-18,1.28E-02,3.10E-02,6.42E-03,0,1.04E-02,0.236886499,1.24E-02,5.42E-02,4.45E-02,9.87E-02,3.31E-02,0,2.37E-02,0.124598703,0,0.136362416,0,8.90E-02,0,0,0,4.00E-02,4.89E-02,1.00E-02,0.104041445,0.285313298,4.09E-02,0,5.32E-02,0,1.08E-02,0,57,92,106,0,0,0,92,0,0,0,0,0.46,NA,NA,-0.728045563,-0.762015393,1.433484996,-1.264967724,0.558911407,-0.579144556,-0.84279916,-0.800823869,-0.694694164,0.421685753,-1.117976774,0.161634387,-0.155458633,-0.233454158,5779.035657,5011.711958,10790.74761,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Endometrium,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 90 %,Positive : 75 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,CK7 - positive; Vimentin - positive;,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,2,12 Months,Yes,Living,54,No,No,No,Tumor Free,Never,Never,Never,Yes,No,Unknown,No,Complete Remission,Complete Remission,n/a,No,n/a,n/a,n/a,n/a,n/a,n/a,n/a,17,n/a,n/a,n/a,n/a,n/a +C3N-02062,C3N-02062,No,b1,1,127C,CPT0134500003,Tumor,No,67,Female,Endometrioid carcinoma,G2 Moderately differentiated,1.3,160,83,32.42,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,NA,0,CNV_L,No,7.00E-02,MSS,CNV_L,73,Mutated,Mutated,WT,Mutated,WT,1.17E-17,1.49E-18,2.43E-03,0,0,0,0,1.08E-02,4.99E-19,5.69E-03,0,9.25E-19,2.89E-02,0,2.42E-03,2.39E-18,0,0,3.02E-17,8.12E-02,2.69E-18,0,9.24E-04,6.94E-03,1.81E-18,0,4.98E-05,0,7.50E-18,4.26E-03,1.72E-02,6.72E-03,2.10E-17,9.40E-02,0.155266913,2.80E-18,6.24E-03,1.22E-18,6.24E-03,0,0,5.31E-02,0,0,0.391955364,0,0,0,0,0,1.96E-02,2.33E-03,0.228128164,5.70E-03,0.246055203,0,1.44E-02,0,1.22E-02,2.65E-02,0,30,36,0,0,0,0,0,0,0,0,0,0.81,NA,NA,-1.698677482,-2.136668882,-0.630072864,0.691906107,-1.301949188,-1.120022429,-1.170332152,-0.782234354,6.70E-02,-1.006483662,-0.921356697,-1.658597955,1.560987255,-0.375566557,1892.523803,1697.25622,3589.780024,Not Examined,Present,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 70 %,Positive : 60 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,CK7 - positive; Vimentin - positive; Estrogen - 70% (+++); Progesterone - 60% (++);,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-02244,C3N-02244,No,b1,2,131C,CPT0128960003,Tumor,No,62,Female,Endometrioid carcinoma,G2 Moderately differentiated,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Not Reported,0,CNV_L,No,0,MSS,CNV_L,48,WT,Mutated,WT,Mutated,WT,9.60E-02,3.63E-02,7.51E-20,2.84E-19,0,2.01E-02,2.74E-02,0,1.04E-03,1.25E-02,0,2.80E-02,8.75E-20,0,1.08E-02,1.90E-02,6.24E-03,8.89E-02,6.45E-19,4.95E-02,2.25E-03,3.05E-03,7.21E-03,5.95E-03,0,0,4.43E-03,2.45E-20,3.38E-19,4.59E-02,1.40E-02,1.04E-02,2.64E-18,3.48E-02,1.44E-04,0,4.17E-02,5.39E-02,9.57E-02,0,5.09E-02,0.122627402,0.109951525,0,0.185850046,0,2.91E-02,1.98E-02,0,0,8.04E-02,5.54E-04,2.79E-02,7.51E-03,0.222394331,6.12E-02,5.95E-03,5.61E-02,0,0,1.97E-02,19,23,0,0,0,0,0,0,0,0,0,0.18,NA,NA,-0.107676348,9.76E-02,0.835401632,-1.123126051,0.169083077,-0.558616744,0.477976782,1.10908511,-0.128160498,0.58329071,0.591609536,1.259272706,-0.747330076,0.646962999,4754.892256,5088.957186,9843.849442,NA,NA,NA,Hispanic or Latino,Hispanic or Latino,Other: unknown,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-02247,C3N-02247,No,b1,3,131N,CPT0265300003,Tumor,No,68,Female,Endometrioid carcinoma,G2 Moderately differentiated,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Unknown,NA,NA,No,7.93,MSI-H,MSI-H,728,WT,Mutated,WT,Mutated,WT,0.253732935,1.87E-02,3.08E-02,0,1.20E-03,4.99E-18,0.103786136,1.89E-03,4.08E-02,7.66E-02,3.74E-20,1.77E-02,2.23E-02,0,2.66E-02,1.26E-02,7.65E-19,0.157565663,0,0.143572972,3.21E-03,4.38E-03,1.46E-02,6.88E-03,0,0,3.10E-03,1.65E-20,3.06E-18,4.78E-03,1.20E-02,1.80E-02,2.73E-18,1.41E-17,0.158750667,3.25E-03,6.49E-02,8.67E-02,0.151643366,0,1.51E-02,1.03E-02,5.37E-02,0,0.31424386,0,0,0,0.165699366,0,0,0,0,0.109844507,0.209919838,6.39E-02,0,5.74E-02,0,0,0,9,64,316,0,0,0,0,92,0,0,72,NA,NA,NA,0.842084468,-1.627463096,-0.356452521,-1.418094345,0.396804101,-1.283228813,-0.169078372,-1.152918335,-0.350436708,-9.69E-02,-0.381885703,1.097287551,-0.5286894,5.67E-02,5290.709291,5725.192064,11015.90136,NA,NA,NA,Hispanic or Latino,Hispanic or Latino,Other: unknown,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-02249,C3N-02249,No,b3,10,130N,CPT0129080003,Tumor,No,64,Female,Endometrioid carcinoma,G2 Moderately differentiated,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,White,0,CNV_L,No,0.06,MSS,CNV_L,63,WT,Mutated,Mutated,Mutated,Mutated,5.57E-02,0,5.59E-19,0,1.39E-18,6.01E-18,1.15E-17,4.21E-19,0,0,8.26E-19,4.56E-18,6.59E-03,0,2.06E-19,5.80E-03,3.39E-18,3.39E-03,3.44E-18,4.51E-02,0,4.97E-03,3.63E-19,0,2.93E-18,1.10E-17,9.93E-19,2.57E-18,7.36E-18,2.96E-02,2.86E-03,7.70E-03,1.17E-18,6.30E-02,4.14E-03,0,1.73E-17,5.23E-03,5.23E-03,0,0,6.12E-02,3.15E-03,0,0.324678703,0,0,0,0,4.20E-02,0,0,0.353641598,6.00E-04,0.155729002,0,3.77E-02,0,1.90E-02,0,2.27E-03,2,24,33,0,0,0,0,0,0,0,0,0.74,NA,NA,-2.45E-02,1.129819654,0.518511803,3.22E-02,-0.524796529,1.285313111,0.188739199,-3.77E-02,-3.73E-02,0.555652879,0.529770126,-1.208466992,0.666095782,1.677119566,3546.884365,3299.669416,6846.553781,NA,NA,NA,Hispanic or Latino,Hispanic or Latino,Other: unknown,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-02253,C3N-02253,No,b4,14,128N,CPT0128770003,Tumor,No,53,Female,Endometrioid carcinoma,G2 Moderately differentiated,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,White,0,CNV_L,Yes,0.15,MSS,POLE,4219,Mutated,Mutated,WT,Mutated,Mutated,0.128769896,2.68E-02,0,2.00E-18,0,3.01E-03,5.52E-02,9.37E-04,6.90E-04,1.47E-02,5.11E-18,1.32E-19,1.97E-18,1.02E-18,2.87E-03,4.53E-18,3.21E-18,1.90E-18,7.86E-19,1.08E-02,3.79E-03,9.47E-03,6.78E-03,5.26E-03,0,0,6.26E-03,3.52E-19,1.33E-17,6.69E-02,2.84E-02,2.27E-02,0,0.100519471,1.63E-02,4.28E-03,2.63E-02,3.22E-18,2.63E-02,2.14E-02,0,5.23E-02,0.110794303,0,0.185194989,0,0.109066725,2.28E-02,0,6.96E-03,3.95E-02,1.94E-02,8.68E-02,8.13E-02,0.156586588,0,0,0.105098029,0,2.63E-03,0,224,117,0,0,1999,1869,0,0,0,0,0,0.76,NA,NA,-0.572640528,-0.221503713,-0.785765328,-0.165927255,1.69308959,-0.224887438,-0.193014583,-1.434108645,-7.85E-02,-1.141704929,-0.248593204,-0.941148449,1.025463306,0.17829777,2333.912514,4295.831047,6629.743562,NA,NA,NA,Not-Hispanic or Latino,Non-Hispanic,Other: unknown,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-02271,C3N-02271,No,b1,3,128C,CPT0181670008,Tumor,No,58,Female,Endometrioid carcinoma,G2 Moderately differentiated,0.7,158,121,48,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,4,Stage I,NA,0,CNV_L,No,0,MSS,CNV_L,31,WT,Mutated,WT,WT,Mutated,6.48E-02,1.68E-02,0,0,0,4.30E-18,3.30E-02,0,0,1.05E-02,5.00E-18,3.08E-02,3.14E-03,1.34E-18,9.52E-03,2.47E-03,1.52E-21,9.94E-18,5.68E-18,2.76E-02,5.43E-03,1.42E-03,7.09E-03,1.03E-02,3.11E-18,7.62E-03,2.38E-03,1.62E-02,5.29E-18,6.52E-18,3.00E-02,2.40E-03,0,4.60E-02,2.96E-02,1.06E-03,4.39E-02,1.23E-03,4.52E-02,3.64E-02,0,5.67E-02,1.36E-02,0,0.276595024,0,1.41E-03,2.26E-02,0,0,8.68E-02,0,6.51E-02,1.72E-02,0.201748072,0,2.38E-02,0,1.79E-02,2.63E-02,0.153909886,9,21,0,0,0,0,0,0,0,0,0,0.25,Yes,No,-1.51E-04,0.747834004,1.239876315,0.394066094,0.997235066,0.80395918,1.218001135,1.504681034,1.20863107,-0.658134259,1.146738531,0.761140661,-0.58700222,1.159577578,3984.425899,5296.834209,9281.260107,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,4 or more,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record|Self-reported and Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,Formetic|Vanatex|Adipine|Citrafleet,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,320|700|1063|1328,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,4 or more|4 or more|4 or more|4 or more,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,335.0|715.0|1078.0|1343.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-02274,C3N-02274,No,b2,5,128C,CPT0182380004,Tumor,No,80,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.5,158,84,33,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,7,Stage I,NA,0.161135217,CNV_L,No,38.49,MSI-H,MSI-H,1368,WT,Mutated,WT,Mutated,WT,0,0,0,2.26E-18,0,8.38E-18,1.80E-17,0,0,4.24E-18,3.17E-18,0,2.11E-02,0,1.72E-18,2.30E-03,1.68E-18,5.28E-18,0,1.73E-21,0,0,1.83E-04,1.30E-04,0,0,1.26E-18,1.01E-18,4.26E-17,2.47E-03,9.03E-03,2.12E-02,1.98E-20,5.46E-02,0.129406267,1.74E-17,8.64E-05,1.15E-03,1.24E-03,1.09E-02,0,0,0,0,0.231365004,0,1.11E-02,2.09E-02,0,5.55E-02,0,0,8.53E-02,2.12E-03,0.138203005,0.135116782,5.15E-02,0,0.161245324,5.50E-03,9.12E-02,0,108,425,0,0,0,0,248,0,0,208,0.6,Yes,No,-0.960910833,-0.35442055,-1.037890741,1.675003725,-1.144594546,7.85E-02,-3.47E-03,-0.563620465,0.314217582,-0.942210883,0.202177414,-1.276107442,1.452148315,-1.168394001,1718.934353,2235.34997,3954.284324,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Lokren|Siofor|Diured|Simvasterol|Lacipil|Vivace,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Deceased,316|615|977|971,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,With Tumor|Tumor Free|Unknown Tumor Status|Unknown Tumor Status,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Persistent Disease|Complete Remission|Unknown|n/a,n/a|n/a|n/a|Unknown,Yes|Yes|Yes|Yes,Distant Metastasis|Distant Metastasis|Distant Metastasis|Distant Metastasis,Brain|Brain|Brain|Brain,258.0|258.0|258.0|279.0,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,No|No|No|No,No|No|No|No,316.0|615.0|977.0|n/a,n/a|n/a|n/a|Cerebrovascular Disorder,n/a|n/a|n/a|1102.0,279.0|279.0|279.0|279.0,Surgical Resection|Surgical Resection|Surgical Resection|Unknown,RX: Presence of Residual Tumor cannot be assessed|RX: Presence of Residual Tumor cannot be assessed|RX: Presence of Residual Tumor cannot be assessed|RX: Presence of Residual Tumor cannot be assessed +C3N-02296,C3N-02296,No,b3,9,129C,CPT0181750004,Tumor,No,83,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.7,150,90,40,Present,=50% myometrial invasion,Seventh Edition (2010),pT2 (FIGO II),pNX,0,Stage II,NA,0,CNV_L,No,17.56,MSI-H,MSI-H,514,WT,Mutated,WT,WT,WT,2.78E-02,5.13E-03,6.67E-20,0,7.87E-18,1.68E-03,6.63E-03,0,1.17E-18,3.05E-18,0,3.98E-19,0,0,5.99E-04,3.51E-19,3.03E-05,1.73E-04,0,1.84E-02,0,0,4.99E-04,1.38E-02,2.39E-20,0,7.49E-03,0,2.32E-19,6.17E-02,1.20E-02,7.64E-03,0,5.47E-02,6.49E-04,8.83E-03,1.30E-02,8.64E-05,1.31E-02,1.87E-02,0,2.57E-03,1.62E-02,0,0.181637678,0,4.45E-02,5.99E-02,0,0,5.67E-02,0,0.402025819,7.70E-03,0.124040119,0,0,0,7.88E-02,0,7.09E-03,37,100,172,0,0,0,0,79,0,0,0,0.85,Yes,No,1.31E-02,-0.317137185,-0.312541962,1.433738033,-0.161056638,-0.797784762,5.44E-02,-0.704653894,1.024086467,-0.80926426,0.234668224,0.606228964,1.094910038,-0.780992912,2602.18226,3024.123206,5626.305465,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Euthyrox|Siofor|Diuresin|Lisiprol|Simvacard,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Deceased,448|750|974|974,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|With Tumor|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Persistent Disease|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|Yes|Yes|Yes,n/a|Locoregional Recurrence|Locoregional Recurrence|Locoregional Recurrence,n/a|Other: vaginal cuff|Other: vaginal cuff|Other: vaginal cuff,n/a|750.0|750.0|750.0,n/a|No|Yes|Yes,n/a|No|No|No,n/a|No|No|No,n/a|No|No|No,448.0|750.0|974.0|n/a,n/a|n/a|n/a|Respiratory Disease,n/a|n/a|n/a|1268.0,n/a|n/a|817.0|817.0,n/a|n/a|Surgical Resection|Surgical Resection,n/a|n/a|R0: No Residual Tumor|R0: No Residual Tumor +C3N-02298,C3N-02298,No,b3,10,131C,CPT0181540008,Tumor,No,83,Female,Endometrioid carcinoma,G1 Well differentiated,4,160,75,29,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,4,Stage I,NA,NA,NA,No,0,MSS,NA,56,WT,Mutated,WT,WT,WT,3.10E-02,2.66E-02,0,0,2.64E-18,0,8.37E-03,1.35E-18,0,2.79E-02,0,1.35E-02,1.45E-02,0,2.58E-03,6.83E-19,0,9.93E-18,0,5.07E-02,5.67E-04,2.74E-19,6.28E-03,8.96E-03,6.38E-19,5.79E-19,1.08E-02,2.65E-19,3.22E-18,1.09E-17,1.69E-02,1.28E-02,6.99E-20,0,2.24E-02,0,2.58E-02,5.31E-18,2.58E-02,4.38E-02,0,4.85E-03,0.141005068,0,0.172691468,0,0,4.35E-02,1.43E-02,0,0,0,0,1.29E-02,0.280991343,1.14E-02,1.50E-02,0.215700909,0,0,4.40E-02,14,34,0,0,0,0,0,0,0,0,0,NA,NA,NA,0.559241776,-0.540152595,0.970245124,1.000307016,-0.780444474,0.369785978,0.174319739,0.76700818,1.01E-02,-1.335195364,0.182926199,-0.703083495,1.340662281,0.239093334,3230.255382,3577.007665,6807.263047,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,clexane|Nitrendypina|Betaloc|Atoris|Nolpaza|Doxar|Tritace|Heparegen,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,378|625|987|1450,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,No|No|No|No,No|No|No|No,2|2|2|2,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,378.0|625.0|987.0|1450.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-02302,C3N-02302,No,b3,11,131C,CPT0181610003,Tumor,No,69,Female,Endometrioid carcinoma,G1 Well differentiated,6.5,160,78,30,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,16,Stage I,NA,2.12E-02,CNV_L,No,0.01,MSS,CNV_L,76,WT,Mutated,Mutated,Mutated,Mutated,5.97E-02,5.82E-03,0,0,0,0,1.93E-18,8.94E-20,0,9.27E-03,3.07E-18,0,4.21E-03,4.50E-20,9.11E-03,0,1.87E-03,1.85E-19,0,8.57E-02,1.96E-02,1.74E-02,1.18E-02,2.56E-03,0,1.35E-02,5.54E-03,6.12E-03,0,2.21E-02,1.30E-02,6.88E-03,2.94E-19,4.81E-02,6.02E-02,6.01E-03,3.90E-02,2.60E-19,3.90E-02,0,0,0.111216784,0.120963476,0,0.172160335,9.29E-03,6.11E-03,0,0,2.73E-02,0,0,6.57E-02,1.58E-03,0.323537185,2.67E-02,7.57E-03,0,0,3.96E-02,8.83E-02,40,33,0,0,0,0,0,0,0,0,0,0.65,Yes,No,0.865147527,-0.131179063,-0.213954775,-0.478838545,-0.369031154,0.146959813,0.585819275,0.688512187,0.315352122,-0.259014447,0.726497766,1.127427742,-0.33141093,0.709827011,3872.297694,4392.003162,8264.300857,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,Ebivol|Diuresin|Karbis|Glucophage 750g,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,503|746|993|1357,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Unknown|Unknown|Unknown|Unknown,Never|Never|Never|Never,Yes|Yes|Yes|Yes,Yes|Yes|Yes|Yes,3|3|3|3,No|No|No|No,Complete Remission|Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,503.0|746.0|993.0|1357.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-02337,C3N-02337,No,b3,12,128C,CPT0136280003,Tumor,No,70,Female,Endometrioid carcinoma,G2 Moderately differentiated,0.8,164,81,30.12,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,10,Stage I,NA,0,CNV_L,No,0.04,MSS,CNV_L,57,WT,Mutated,WT,Mutated,WT,3.95E-02,4.23E-03,1.92E-19,0,0,1.19E-02,1.99E-18,3.58E-19,4.59E-03,8.66E-03,0,7.50E-03,0,0,2.90E-04,9.72E-03,0,8.86E-19,3.76E-18,4.45E-02,0,0,2.98E-04,2.15E-02,8.04E-20,6.88E-19,7.69E-03,0,3.32E-18,3.83E-03,1.70E-02,1.11E-02,0,2.57E-02,2.25E-02,1.19E-02,2.04E-02,4.86E-03,2.53E-02,0,2.42E-02,0,0,0,0.378661096,0,5.29E-02,2.82E-02,0,3.70E-02,7.47E-02,3.59E-02,0.184791056,2.53E-02,0.146671385,0,1.13E-02,5.60E-04,0,0,0,16,20,0,0,0,0,16,0,0,0,0,0.34,NA,NA,0.634611046,-0.706436551,-0.655793985,-0.747967565,-0.569300874,-0.398115283,-1.97E-02,-0.318297464,0.822338019,-0.38505721,-3.84E-02,-1.81E-02,-0.534978146,0.156357041,3157.377031,3626.221991,6783.599023,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,2,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-02372,C3N-02372,No,b2,7,131N,CPT0137140008,Tumor,No,54,Female,Endometrioid carcinoma,G2 Moderately differentiated,1.3,173,90,30.07,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,10,Stage I,NA,6.32E-02,CNV_L,No,22.4,MSI-H,MSI-H,1310,WT,Mutated,WT,Mutated,WT,0.178237985,9.34E-03,2.67E-02,2.06E-19,3.95E-03,0,4.67E-02,1.07E-02,3.51E-02,5.21E-02,4.64E-03,2.84E-03,2.60E-02,1.55E-20,4.54E-02,3.86E-02,9.84E-03,0.141676588,8.44E-03,0.103320842,3.06E-02,2.71E-02,6.42E-03,1.02E-02,0,4.46E-03,1.54E-03,0,0,4.03E-03,7.93E-02,7.24E-03,0,0,0.359208259,7.91E-03,9.93E-02,0.1003232,0.199631902,4.33E-02,0,5.25E-02,0.106278504,0,0.194169252,4.47E-02,7.03E-02,0,0,0,6.94E-02,7.01E-04,1.53E-02,0.113468193,0.221076784,2.20E-02,3.38E-03,3.23E-02,0,1.62E-03,9.46E-03,374,240,0,0,0,0,383,0,0,0,0,0.17,NA,NA,-0.230424072,-0.118166316,0.795624078,-0.299328933,4.20E-02,-0.27518029,-0.132789313,-0.562002205,0.238820503,0.759833964,-0.335783349,0.774896022,-0.626412557,-0.637548054,6356.338308,5859.178928,12215.51724,Not Examined,Present,Margins uninvolved by invasive carcinoma,NA,Slavonic,Ukraine,Other,Entire uterine cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,Unknown,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,NA,NA,NA,NA,NA,NA,Yes,2,12 Months|24 Months,No|No,Living|Living,372|818,No|No,No|No,No|No,Tumor Free|Tumor Free,Never|Never,Never|Never,Never|Never,No|No,No|No,Unknown|Unknown,No|No,Complete Remission|Complete Remission,Complete Remission|Complete Remission,n/a|n/a,No|No,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,341.0|787.0,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a,n/a|n/a +C3N-02436,C3N-02436,No,b4,14,131C,CPT0115530003,Tumor,No,51,Female,Endometrioid carcinoma,G1 Well differentiated,8,160,122,47.47,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,13,Stage I,White,7.67E-02,CNV_L,No,35.64,MSI-H,MSI-H,1253,Mutated,Mutated,WT,Mutated,WT,4.93E-02,2.46E-02,1.13E-19,0,2.30E-19,4.88E-18,5.68E-02,1.46E-03,1.74E-02,5.43E-02,3.13E-03,8.39E-03,2.50E-20,0,4.68E-02,0,4.46E-03,8.24E-18,1.14E-18,1.08E-02,3.04E-02,3.05E-02,1.36E-02,2.95E-03,0,7.53E-18,5.45E-03,1.46E-18,1.43E-17,3.20E-02,4.41E-02,8.30E-03,0,0.136260905,7.79E-02,1.31E-02,8.44E-02,4.12E-18,8.44E-02,0,0,1.57E-02,0.111668301,0,0.227725853,1.06E-02,3.43E-02,7.03E-02,0,3.08E-02,2.81E-02,0,0.107232895,7.35E-02,0.274861568,1.75E-03,0,1.35E-02,0,0,0,178,207,0,0,0,0,275,119,0,0,82,0.48,Yes,No,0.130519566,-0.197965889,0.586393386,-0.469053254,6.58E-02,-1.330719595,-1.093150363,-0.530102096,1.141768576,-1.051315758,-1.326021881,0.446566161,0.707129872,-1.509491247,4096.108384,5571.055976,9667.16436,Atypical and/or suspicious,Not identified,Cannot be assessed,Not-Hispanic or Latino,white,United States,Other,entire endometrial cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Premenopausal: less than 6 months since LMP AND no prior bilateral oophorectomy AND not on estrogen replacement,Never,1,ERG in A12: positive for lymphovascular invasion,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,tylenol|ferrous sulfate|lisinopril-hydrochlorothiazide|potassium chloride CR|zoloft,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,332|740|1103|1502,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Unknown|Unknown|Unknown|Unknown,Never|Never|Never|Never,Yes|Yes|Yes|Yes,No|No|No|No,1|1|1|1,No|No|No|No,Not Applicable|Not Applicable|Not Applicable|Not Applicable,Complete Remission|Complete Remission|Not Applicable|n/a,n/a|n/a|n/a|Not Applicable,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,299.0|707.0|1070.0|1469.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-02437,C3N-02437,No,b1,1,128C,CPT0159110003,Tumor,No,61,Female,Endometrioid carcinoma,G2 Moderately differentiated,4.8,163,156,58.87,Present,=50% myometrial invasion,Seventh Edition (2010),pT3a (FIGO IIIA),pN0,27,Stage III,White,0,CNV_L,No,8.52,MSI-H,MSI-H,323,WT,Mutated,Mutated,Mutated,Mutated,5.03E-02,0,5.42E-04,4.89E-18,4.13E-19,0,3.32E-19,4.65E-03,1.04E-02,2.81E-03,0,3.43E-19,3.57E-20,0,3.61E-03,1.72E-19,0,1.43E-17,0,1.67E-02,1.23E-19,0,1.11E-19,4.16E-03,0,0,2.39E-03,0,7.35E-18,2.29E-04,2.42E-02,1.50E-02,2.05E-03,4.23E-02,9.91E-02,1.34E-02,1.21E-02,7.34E-18,1.21E-02,0,1.48E-03,0,2.00E-02,0,0.28938527,0,5.16E-03,7.16E-03,0,0,5.78E-02,0,0.259374602,3.83E-02,0.155608113,2.98E-02,8.39E-02,0,2.84E-02,1.26E-02,1.10E-02,0,51,141,0,0,0,0,36,0,0,0,0.76,NA,NA,0.846722283,-0.101513466,-0.144841051,0.91979873,-0.17787433,0.787821688,0.806534529,0.473683518,1.193911538,-0.651134294,0.672034779,-1.17935931,0.537376115,1.365153275,3061.091476,3498.932238,6560.023713,Negative for malignancy/normal/benign,Not identified,Cannot be assessed,Not-Hispanic or Latino,white,United States,Other,anterior and posterior,Multifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,Prussian blue stain for iron: highlights hemosiderin (control positive); Kinyoun stain for mycobacteria: negative (control positive),NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,aspirin|carvedilol|clonidine|cyproheptadine|furosemide|naproxen sodium|potassium chloride|valsartan,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,308|764|1036,Yes|Yes|Yes,Yes|Yes|Yes,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Yes|Yes|Yes,No|No|No,2|2|2,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,290.0|746.0|1018.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02595,C3N-02595,No,b4,15,130N,CPT0181810004,Tumor,No,41,Female,Endometrioid carcinoma,G3 Poorly differentiated,10,165,50,18,Present,=50% myometrial invasion,Seventh Edition (2010),pT3a (FIGO IIIA),pN1 (FIGO IIIC1),22,Stage IV,NA,1.371947271,CNV_L,No,26.97,MSI-H,MSI-H,1133,WT,Mutated,WT,Mutated,Mutated,9.03E-02,6.03E-03,7.52E-03,0,3.93E-18,2.97E-19,4.97E-03,5.57E-03,2.10E-04,2.26E-02,3.43E-18,1.76E-03,2.74E-02,2.12E-18,8.13E-03,5.30E-19,1.22E-19,0,1.46E-17,2.58E-02,1.28E-02,7.54E-03,4.20E-03,9.07E-03,0,2.46E-19,4.47E-03,0,0,1.11E-02,1.93E-02,8.40E-03,3.62E-19,2.62E-02,0.164645203,0,2.42E-02,2.65E-19,2.42E-02,4.14E-03,0,0.11398473,4.32E-02,0,0.214473912,0,3.41E-02,0,1.96E-02,0,3.62E-02,0,0.12359541,5.96E-02,0.240601901,3.81E-02,0,0,3.10E-02,1.90E-02,2.24E-02,69,6,424,0,0,0,0,173,0,0,104,0.34,NA,NA,-0.216454753,0.610482789,0.80700581,0.530336339,-0.566719449,0.98811317,0.523465296,6.99E-02,2.71E-02,-0.432048403,0.439976356,-0.620225453,-0.401425309,0.272969203,3858.489953,4137.281022,7995.770975,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Other,Fundus and lower part with isthmus - infiltration of the cervix,Multifocal,IHC staining not done,3,11,IHC staining not done,0,0,IHC staining not done,0,cM1,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,No,Cannot be determined,No,Premenopausal: less than 6 months since LMP AND no prior bilateral oophorectomy AND not on estrogen replacement,Never,None,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Olanzapin|Pantoprazol|Exacyl|Cyclonamine|Hydroxyzinum|Clexane,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,489|721|980,Yes|Yes|Yes,Yes|Yes|Yes,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Unknown|Unknown|Unknown,Never|Never|Never,No|No|No,No|No|No,None|None|None,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,509.0|741.0|1000.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02598,C3N-02598,No,b3,12,131N,CPT0187960004,Tumor,No,60,Female,Endometrioid carcinoma,G2 Moderately differentiated,8,157,54,21,Present,=50% myometrial invasion,Seventh Edition (2010),pT4 ((FIGO IVA),pN2 (FIGO IIIC2),0,Stage IV,NA,3.83E-02,CNV_L,No,6.41,MSI-H,MSI-H,941,Mutated,Mutated,WT,Mutated,WT,9.62E-02,8.72E-05,4.48E-03,0,0,3.57E-18,3.91E-02,6.18E-05,8.79E-04,2.71E-02,1.23E-18,0,1.47E-02,0,8.97E-03,1.66E-02,6.19E-19,7.13E-02,0,3.09E-02,2.13E-02,1.36E-02,8.88E-03,7.09E-21,2.88E-19,1.09E-02,4.35E-03,2.28E-03,5.20E-18,3.30E-03,1.47E-02,6.50E-03,7.17E-18,7.55E-03,8.71E-02,1.87E-03,2.97E-02,4.64E-02,7.61E-02,0,0,4.11E-02,4.24E-02,0,0.291548358,0,1.26E-02,0,0,0,4.02E-02,0,6.08E-02,3.22E-02,0.144917984,9.65E-02,0,0,0.106095108,4.69E-02,8.47E-02,149,35,507,0,0,0,0,194,0,0,0,0.49,NA,NA,0.486631463,1.234906624,-1.228286315,1.321823493,-0.744782971,1.954233069,1.32086742,0.304020926,0.114762218,1.056982929,1.30256427,-0.555580639,1.436945537,1.452465137,5311.754482,4933.694273,10245.44875,Not Examined,Not identified,Margin(s) involved by invasive carcinoma,NA,Caucasian,Poland,Other,"Istmus, cervical canal and fundus and anterior wall of uterine corpus",Unifocal,0,0,6,1,1,1,0,0,cM1,R0: No residual tumor,Positive : % Not available,Negative,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Current smoker: Includes daily and non-daily smokers,Unknown,NA,20,NA,Yes,Self-reported and Medical Record,Yes,Medical Record|Medical Record,Citrafleet|Fragmin,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,267|659|1068,No|No|No,Yes|Yes|Yes,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Never|Never|Never,Never|Never|Never,No|No|No,No|No|No,2|2|2,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,267.0|659.0|1068.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02631,C3N-02631,No,b3,11,128N,CPT0181960004,Tumor,No,77,Female,Serous carcinoma,G3 Poorly differentiated,8,156,75,30.82,Present,<50% myometrial invasion,Seventh Edition (2010),pT2 (FIGO II),pN0,6,Stage II,NA,26.26196116,CNV_H,No,0.86,MSS,CNV_H,64,Mutated,WT,WT,WT,Mutated,0,0,4.91E-19,0,0,0,5.03E-18,8.80E-03,1.00E-17,0,2.21E-18,0,2.05E-02,0,0,6.27E-03,0,2.02E-02,0,0.103686034,0,4.42E-19,2.37E-04,2.88E-19,0,0,8.25E-19,8.38E-19,9.80E-18,3.86E-02,1.06E-02,1.24E-02,7.65E-18,5.82E-02,0.189308078,2.64E-18,1.40E-17,1.38E-02,1.38E-02,0.157999115,0,2.52E-02,4.79E-02,0,6.51E-03,0,0.134292989,0,0,0,7.99E-02,7.69E-04,3.93E-02,0,0.269409935,0,0.20074118,3.79E-02,0,0,0,13,48,0,0,0,0,0,0,0,0,0,0.47,Yes,No,-0.571092058,-1.151372585,-0.862799493,-1.536707086,-0.278985331,-0.542342851,-2.460955649,-1.061078949,0.503625473,-0.398774199,-2.501241837,-2.674330255,0.218722636,-2.383170511,2213.438711,865.788058,3079.226769,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Multifocal,IHC staining not done,0,8,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 5 %,Positive : 5 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,1,"Vimentin (+)-5%,p16 (+)-95%,CEA(+)-1%, CK5/6(+)-1%",NA,Yes,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Self Report|Self Report|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Beto ZK|Atoris|Glucophage |Polpril|Verospiron,Melanoma malignum,Self Report,Surgery,Unknown,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,291|679|1107,No|No|No,Yes|Yes|Yes,No|No|No,Tumor Free|With Tumor|Tumor Free,Never|Never|Never,Never|Never|Never,Never|Never|Never,Yes|Yes|Yes,Yes|Yes|Yes,1|1|1,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Persistent Disease|n/a,n/a|n/a|Complete Remission,No|Yes|No,n/a|Distant Metastasis|n/a,n/a|Other: abdomen wall near umbilicus|n/a,n/a|679.0|n/a,n/a|No|n/a,n/a|No|n/a,n/a|No|n/a,n/a|No|n/a,291.0|679.0|1107.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02632,C3N-02632,No,b1,1,129N,CPT0182020004,Tumor,No,57,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.8,174,89,29,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,3,Stage I,NA,0,CNV_L,No,0.02,MSS,CNV_L,63,WT,Mutated,WT,Mutated,WT,2.95E-02,3.88E-03,0,4.77E-18,0,0,3.54E-18,0,1.16E-17,5.48E-20,3.48E-17,0,2.80E-03,1.87E-18,9.09E-23,0,0,1.18E-18,0,3.50E-02,8.83E-04,1.83E-04,4.80E-03,7.42E-03,3.50E-18,9.45E-04,6.69E-03,4.08E-02,2.68E-17,0,9.09E-03,6.40E-03,1.50E-18,6.09E-02,3.20E-02,5.30E-19,3.59E-02,5.90E-19,3.59E-02,0,7.20E-03,2.33E-04,8.20E-05,0,0.325105995,0,2.63E-02,2.31E-02,0,0,0.137976343,0,3.03E-02,0,3.59E-02,0,1.20E-02,0,6.40E-02,1.70E-02,0.320842759,18,17,0,0,0,0,22,0,0,0,0,0.56,NA,NA,-0.434784163,-0.24884144,-0.494035294,1.053296563,-0.48604084,-8.09E-02,1.640355071,0.380147841,0.865443951,-0.647115205,1.47754223,-0.37469067,1.152536238,0.877684072,3054.31647,4676.254457,7730.570926,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,None,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Euthyrox|Citrafleet|Fragmin|Cipronex|Natrium kalium|Dormicum,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months|48 Months,No|No|No|No,Living|Living|Living|Living,497|859|960|1405,No|No|No|No,No|No|No|No,No|No|No|No,Tumor Free|Tumor Free|Tumor Free|Tumor Free,Never|Never|Never|Never,Never|Never|Never|Never,Never|Never|Never|Never,No|No|No|No,No|No|No|No,Unknown|Unknown|Unknown|Unknown,No|No|No|No,Unknown|Unknown|Complete Remission|Complete Remission,Unknown|Complete Remission|Complete Remission|n/a,n/a|n/a|n/a|Complete Remission,No|No|No|No,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,510.0|872.0|973.0|1418.0,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a,n/a|n/a|n/a|n/a +C3N-02635,C3N-02635,No,b4,13,127N,CPT0182070004,Tumor,No,56,Female,Endometrioid carcinoma,G3 Poorly differentiated,3,150,80,35,Present,=50% myometrial invasion,Seventh Edition (2010),pT2 (FIGO II),pN1 (FIGO IIIC1),9,Stage II,NA,13.35596277,CNV_H,No,0.5,MSS,CNV_H,66,WT,Mutated,WT,WT,Mutated,0.115812689,2.67E-02,5.25E-20,5.88E-18,1.58E-19,8.31E-19,4.49E-18,3.86E-19,7.54E-19,0,9.99E-18,0,8.17E-03,0,1.34E-19,6.86E-03,0,6.20E-18,1.23E-18,6.24E-02,2.02E-02,2.33E-02,1.57E-02,1.76E-03,0,0,1.42E-03,0,0,1.28E-03,1.55E-02,3.92E-02,8.63E-18,6.46E-02,0.130536771,0,3.24E-02,3.79E-03,3.62E-02,0,7.52E-03,8.39E-02,3.94E-02,0,0.109467339,0,2.37E-02,0,0,0,3.38E-02,0,9.46E-02,1.41E-02,0.352609746,0,0.143849245,6.03E-02,0,0,3.68E-02,14,14,0,0,0,11,17,0,0,0,0,0.83,Yes,No,-0.728620323,-0.21165115,-6.94E-02,0.210879394,2.078698042,-0.708728998,-0.145974832,0.243789143,0.259294703,-0.791693064,-5.03E-02,-1.681788585,0.429710828,-1.149392898,3589.221054,3933.817101,7523.038154,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,IHC staining not done,1,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Siofor|enalapril|Vastan,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,330|619|1025,Yes|Yes|Yes,Yes|Yes|Yes,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Unknown|Unknown|Unknown,Never|Never|Never,Yes|Yes|Yes,Yes|Yes|Yes,3|3|3,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|Complete Remission,n/a|n/a|n/a,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,330.0|619.0|1025.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02636,C3N-02636,No,b4,14,127N,CPT0182150003,Tumor,No,72,Female,Endometrioid carcinoma,G1 Well differentiated,5.5,157,83,33,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,3,Stage I,NA,1.163072893,CNV_L,No,0.11,MSS,CNV_L,74,WT,WT,Mutated,Mutated,WT,2.68E-02,0,0,5.37E-20,0,4.48E-18,0,3.39E-03,6.22E-20,2.62E-03,0,1.16E-18,8.70E-03,6.32E-19,5.10E-20,1.77E-03,2.31E-19,6.96E-02,1.55E-18,8.65E-03,2.38E-21,1.75E-03,2.13E-04,1.24E-03,5.66E-19,0,2.47E-03,2.91E-04,0,9.28E-03,5.21E-03,7.97E-03,4.48E-18,3.37E-02,0.106936974,4.45E-18,1.02E-03,3.73E-02,3.84E-02,1.78E-02,0,4.00E-02,5.71E-02,0,0.180180067,0,4.22E-02,3.86E-02,0,0.117838441,0,3.84E-02,3.54E-02,2.36E-02,0.121293967,1.16E-02,4.19E-02,0,0.137790059,9.42E-02,2.20E-03,12,22,0,0,0,9,22,0,0,0,0,0.64,NA,NA,1.098775714,-0.170872415,-0.648246186,1.574011104,-0.398238555,0.467888856,8.84E-02,0.145085363,0.263673245,0.301099209,0.307669417,-4.41E-02,-0.668321467,0.925265962,3856.040287,2842.949468,6698.989755,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Other,Fundus (main tumor) and isthmus (implants),Multifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,None,Vimentin positive,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Tritace|Clexane|Citrafleet,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,361|676|1096,Yes|Yes|No,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Never|Never|Never,Never|Never|Never,Yes|Yes|Yes,No|No|No,None|None|1,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,382.0|697.0|1117.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02637,C3N-02637,No,b4,15,131C,CPT0182210004,Tumor,No,53,Female,Endometrioid carcinoma,G2 Moderately differentiated,3,168,138,48,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pNX,0,Stage I,NA,4.45E-03,CNV_L,Yes,0.18,MSS,POLE,7455,Mutated,Mutated,WT,Mutated,Mutated,0.148903082,8.86E-02,9.68E-03,1.00E-03,0,0,6.56E-03,3.28E-03,0,2.46E-02,1.16E-17,1.67E-02,1.07E-02,0,1.62E-02,2.86E-03,4.92E-18,0,2.54E-19,2.34E-02,1.74E-02,2.30E-02,3.86E-04,1.10E-02,2.04E-02,0,2.83E-02,1.15E-19,1.63E-17,4.73E-02,9.35E-02,1.09E-02,4.24E-18,5.86E-02,0.200077682,1.93E-02,8.88E-02,1.43E-03,9.02E-02,5.41E-02,1.40E-02,1.68E-02,5.74E-02,0,0.154482517,0.101144466,7.98E-02,0,0,6.17E-02,0,0,8.35E-02,7.39E-02,0.207691672,0,0,0,6.11E-02,0,3.43E-02,485,0,0,0,2248,4706,0,0,0,0,0,0.65,NA,NA,-0.153843257,0.180211463,0.195008256,0.890892324,-1.25804392,1.127235908,0.520790353,-1.328790363,0.885768342,-1.117668355,0.266184135,6.17E-02,1.020523657,0.379026749,3953.376146,5441.827192,9395.203338,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 70 %,Positive : 80 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,Yes,Cannot be determined,Unknown,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,1,"EMA (+), Vimentin (+), CD10 (+)",NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record,No,NA,NA,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,302|687|1135,Yes|No|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Never|Never|Never,Never|Never|Never,No|No|No,No|No|No,1|1|1,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Patient Deceased,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,302.0|687.0|1135.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02639,C3N-02639,No,b4,14,130N,CPT0182290003,Tumor,No,59,Female,Endometrioid carcinoma,G3 Poorly differentiated,9,157,78,31,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,13,Stage I,NA,31.81337824,CNV_H,No,1.41,MSS,CNV_H,53,Mutated,WT,WT,WT,WT,6.77E-03,0,6.60E-20,4.04E-18,0,0,2.86E-18,8.21E-05,2.71E-18,4.39E-18,0,1.49E-18,1.02E-02,0,1.36E-19,3.02E-03,0,0,0,0.130277113,0,1.13E-03,0,1.51E-20,0,0,0,4.57E-19,6.20E-19,0,1.28E-02,7.74E-03,0,7.78E-03,0.166392433,6.78E-18,2.62E-18,6.05E-03,6.05E-03,2.90E-03,0,3.12E-02,3.13E-02,0,0,0,4.80E-02,0.11176199,0.100421579,1.70E-03,0,3.77E-02,0.109428011,0,5.06E-02,0,0.244140879,0.206347578,0,2.45E-02,0,14,24,0,12,0,0,0,0,0,0,0,0.75,NA,NA,0.767210751,2.36E-03,0.317344385,0.977599381,0.586863491,0.245999258,-1.26931856,0.398623514,1.560387177,-0.402292938,-1.053987618,-0.373247649,0.285155769,-0.823684333,3045.532716,2255.926224,5301.45894,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Multifocal,0,0,6,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : 10 %,Positive : 20 %,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,3,"EMA (+), Vimentin (+), CD10 (-), CK8/18(+),CK5/6(-),bcl2(+),SMA(-),DES(-)",NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Beto ZK|Nitrendypina|Tritace|Signopan|Solpadeine,NA,NA,NA,NA,Yes,1,12 Months|24 Months,No|No,Living|Deceased,294|703,Yes|Yes,Yes|Yes,Yes|Yes,With Tumor|Tumor Free,Never|Never,Never|Never,Never|Never,Yes|Yes,No|Yes,3|1,No|No,Persistent Disease|Persistent Disease,Persistent Disease|Persistent Disease,n/a|n/a,Yes|Yes,Distant Metastasis|Distant Metastasis,"Other: peritoneum, omentum majus, ascites|Other: peritoneum, omentum majus, ascites",324.0|324.0,No|No,No|No,Yes|Yes,No|No,294.0|n/a,n/a|Malignant Neoplasm,n/a|526.0,n/a|n/a,n/a|n/a,n/a|n/a +C3N-02678,C3N-02678,No,b3,11,130C,CPT0182340004,Tumor,No,69,Female,Endometrioid carcinoma,G1 Well differentiated,5.5,164,66,24,Present,=50% myometrial invasion,Seventh Edition (2010),pT2 (FIGO II),pN0,8,Stage II,NA,0,CNV_L,No,13.39,MSI-H,MSI-H,482,WT,Mutated,Mutated,Mutated,WT,3.74E-02,2.39E-04,0,1.32E-18,0,1.70E-19,7.54E-03,1.01E-19,1.61E-20,0,0,2.06E-18,2.34E-02,0,2.22E-03,6.29E-03,0,8.00E-03,0,4.63E-02,0,1.57E-04,4.53E-03,5.24E-03,0,0,1.66E-04,5.08E-19,5.37E-18,8.01E-03,2.89E-02,1.30E-02,4.87E-21,2.94E-02,6.51E-02,4.02E-03,5.13E-03,8.38E-03,1.35E-02,1.29E-02,0,0.186416001,0,0,0.299349686,2.43E-02,0,0,0,0,0,2.23E-02,0.283531578,1.28E-02,0.104148659,1.85E-02,0,1.99E-02,0,0,1.59E-02,56,57,0,0,0,0,247,0,0,0,0,0.46,NA,NA,0.931996304,-0.234767653,-0.529491834,0.715090167,-1.207887158,0.438337251,4.22E-02,0.16601276,1.021736144,0.611077934,0.259159624,6.02E-02,0.151047993,1.262981778,3790.01119,3673.92532,7463.93651,Not Examined,Present,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Unifocal,IHC staining not done,0,1,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,Unknown,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,Concor|Tulip|Afobam|Zyrtec,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Deceased,266|707|580,Yes|Yes|Yes,No|No|No,No|No|No,With Tumor|With Tumor|With Tumor,Never|Never|Never,Never|Never|Never,Never|Never|Never,Yes|Yes|Yes,No|No|No,Unknown|Unknown|2,No|No|No,Persistent Disease|Persistent Disease|Complete Remission,Persistent Disease|Persistent Disease|n/a,n/a|n/a|Patient Deceased,Yes|Yes|Yes,Distant Metastasis|Distant Metastasis|Distant Metastasis,Lung|Lung|Lung,266.0|545.0|545.0,No|No|No,No|No|No,Yes|No|Yes,No|No|No,266.0|707.0|n/a,n/a|n/a|Uterine Corpus Cancer,n/a|n/a|598.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02789,C3N-02789,No,b4,13,131N,CPT0186010004,Tumor,No,61,Female,Endometrioid carcinoma,G2 Moderately differentiated,3.5,147,56,25.7,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,17,Stage II,White,NA,NA,No,12.08,MSI-H,MSI-H,420,WT,Mutated,Mutated,Mutated,WT,0.141682818,1.13E-02,0,2.58E-18,0,5.61E-18,1.31E-18,6.96E-03,2.75E-02,4.14E-02,0,2.36E-03,2.05E-02,1.90E-18,4.20E-03,0,0,0,1.70E-18,6.02E-04,3.89E-02,2.44E-02,1.94E-02,1.50E-03,0,2.39E-03,9.87E-03,6.66E-03,0,5.42E-03,3.69E-02,2.11E-03,5.83E-18,1.57E-02,0.183682185,0,6.16E-02,4.00E-19,6.16E-02,0,0,3.47E-03,3.86E-02,0,0.144920809,5.21E-03,2.55E-02,0,2.58E-02,0,2.70E-02,0,8.46E-02,7.32E-02,0.317682796,2.23E-02,0,0,9.71E-02,5.60E-02,7.85E-02,13,16,169,0,0,0,0,58,0,0,48,NA,NA,NA,0.552801952,0.918609667,-3.34E-02,-0.767812714,0.630192871,1.229641589,1.659742073,1.123896171,1.512568695,-0.490776871,1.38183436,-0.651425363,0.749161776,0.274117739,3305.802106,4866.046928,8171.849034,Positive for malignancy,Present,Cannot be assessed,Not-Hispanic or Latino,white,United States,Other,entire cavity,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM1,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,Unknown,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Current Therapy,1,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,"Current reformed smoker, more than 15 years",20,21,2,0.1,Exposure to secondhand smoke history not available,NA,Yes,Medical Record|Medical Record|Medical Record,calcium carbonate|lysine|Multivitamin,NA,NA,NA,NA,No,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,285|725|1137,Yes|Yes|Yes,Yes|Yes|Yes,No|No|No,Tumor Free|Tumor Free|Tumor Free,Former Therapy|Former Therapy|Former Therapy,Former Therapy|Former Therapy|Former Therapy,Unknown|Unknown|Unknown,No|No|No,No|No|No,1|1|1,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,255.0|695.0|1107.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02947,C3N-02947,No,b2,8,128N,CPT0158520008,Tumor,No,51,Female,Endometrioid carcinoma,G2 Moderately differentiated,5.5,170,65,22.39,Present,=50% myometrial invasion,Seventh Edition (2010),pT1 (FIGO I),pN0,2,Stage I,White,0,CNV_L,No,30.36,MSI-H,MSI-H,921,Mutated,Mutated,WT,Mutated,Mutated,7.35E-02,2.04E-02,8.11E-03,0,1.88E-20,4.85E-18,3.68E-02,8.23E-03,4.32E-03,0,0,4.71E-03,2.74E-02,0,0,3.40E-03,0,0,0,1.28E-02,7.26E-03,7.76E-03,5.17E-03,4.51E-03,0,0,6.09E-03,0,1.44E-17,1.34E-02,2.71E-02,2.15E-02,0,4.86E-02,0.194891097,3.70E-19,2.43E-02,1.70E-03,2.60E-02,1.69E-02,0,6.58E-02,0.119800608,0,0.232481626,4.00E-02,0.100749453,0,0,0,2.42E-02,6.32E-03,0.168448027,2.04E-02,5.51E-02,0,5.57E-02,0,9.39E-02,1.44E-04,0,60,0,364,0,0,0,0,115,0,0,91,0.57,NA,NA,-1.019201651,1.030815245,-1.253029177,0.700607819,-1.151180079,1.29795756,0.897221983,-0.317105163,1.2015646,-4.09E-02,0.850381647,-0.936510283,-7.70E-02,-0.670449534,3107.034864,4311.345097,7418.379961,Positive for malignancy,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,white,United States,Other,anterior and posterior,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Premenopausal: less than 6 months since LMP AND no prior bilateral oophorectomy AND not on estrogen replacement,Unknown,None,NA,NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Current smoker: Includes daily and non-daily smokers,Unknown,NA,5,NA,Exposure to secondhand smoke history not available,Medical Record,Yes,Medical Record|Medical Record,acetaminophen |hydrocodone-acetaminophen,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|Yes,Living|Living|Living,331|856|856,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,No|No|No,No|No|No,None|None|None,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,331.0|856.0|856.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02972,C3N-02972,No,b4,15,131N,CPT0159220008,Tumor,No,74,Female,Endometrioid carcinoma,G2 Moderately differentiated,4.1,152,88,38.08,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN1 (FIGO IIIC1),19,Stage III,White,0,CNV_L,No,0.03,MSS,CNV_L,77,Mutated,Mutated,WT,Mutated,Mutated,0.11022494,6.88E-04,1.55E-19,0,1.54E-19,0,0,3.90E-19,2.32E-18,8.85E-04,9.31E-18,1.26E-02,6.92E-03,1.50E-18,3.79E-03,4.27E-03,4.92E-20,4.07E-18,0,4.22E-02,3.72E-03,7.21E-03,4.05E-03,1.76E-03,0,4.09E-18,5.44E-20,1.11E-03,0,2.97E-18,1.73E-02,8.54E-04,2.02E-19,4.50E-02,4.79E-02,2.55E-19,7.38E-03,2.14E-03,9.52E-03,0,0,8.36E-03,6.10E-02,0,0.245884886,0,4.87E-02,1.69E-02,0,0,7.72E-02,1.21E-02,0,2.99E-02,0.239081182,0,4.08E-02,0,0.118302791,3.62E-02,6.54E-02,30,37,0,0,0,0,0,0,0,0,0,0.26,Yes,Yes,-8.51E-02,1.335986316,0.430705105,0.985335445,1.352598595,1.266359789,1.749552285,1.33586285,0.185018664,-4.60E-02,1.84529309,0.477400599,1.069508234,1.19664878,4104.78479,4741.808055,8846.592846,Negative for malignancy/normal/benign,Not identified,Margins uninvolved by invasive carcinoma,Not-Hispanic or Latino,white,United States,Other,Anterior and Posterior,Unifocal,IHC staining not done,1,3,IHC staining not done,0,0,IHC staining not done,0,Staging Incomplete,RX: Presence of residual tumor cannot be assessed,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,Unknown,Cytokeratin polytypic: positive ;PAX 8: positive;MOC31: negative;WT-1: negative; Vimentin: positive ; P16: mosaic pattern,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,Exposure to secondhand smoke history not available,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,acetaminophen-codeine|aspirin |ducolax|zyrtec|Vitamin D|celexa|glucotrol|hydrochlorothiazide|lisinopril|magnesium oxide|metformin|metoprolol|multi-vitamin (centrum women)|prilosec|pravachol,NA,NA,NA,NA,Yes,2,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,293|874|1202,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Unknown|Unknown|Unknown,Yes|Yes|Yes,Yes|Yes|Yes,Unknown|Unknown|Unknown,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,251.0|832.0|1160.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02976,C3N-02976,No,b2,7,129C,CPT0188030003,Tumor,No,70,Female,Endometrioid carcinoma,G3 Poorly differentiated,3,162,71,27,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,5,Stage I,NA,1.93E-03,CNV_L,No,36.12,MSI-H,MSI-H,941,WT,Mutated,WT,Mutated,WT,6.33E-02,5.21E-02,1.05E-03,2.43E-18,0,7.86E-18,3.93E-18,1.20E-02,0,4.02E-19,0,0,5.70E-02,0,1.82E-02,2.09E-03,2.20E-18,6.16E-18,7.10E-19,3.76E-02,7.72E-03,2.86E-03,3.12E-03,4.92E-03,0,2.38E-17,5.80E-03,0,1.32E-17,1.53E-02,3.00E-02,2.63E-02,1.53E-02,0.147520061,0.179113386,2.46E-19,5.53E-02,1.04E-03,5.63E-02,8.60E-02,0,0.155100744,6.62E-02,0,9.28E-02,2.26E-02,0.12414492,0,0,0,8.89E-02,5.80E-03,0,0.125798131,0.206497607,2.62E-02,0,0,0,0,0,47,136,198,0,0,0,251,0,0,0,0,0.87,NA,NA,-1.406703087,-0.838490699,-2.850650419,0.232913116,-1.143521854,3.05E-02,-2.005926455,-0.301137126,1.390983307,-0.79777691,-2.206948571,-0.939906875,1.65E-02,-1.87197721,1502.789371,3084.663181,4587.452552,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,IHC staining not done,0,6,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Beto 2K|Fragmin|Dormicum|Fortrans|Kalipoz,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,364|670|1076,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Never|Never|Never,Never|Never|Never,Yes|Yes|Yes,No|No|No,2|2|2,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,381.0|687.0|1093.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02978,C3N-02978,No,b4,16,131C,CPT0244470003.1,Tumor,No,66,Female,Endometrioid carcinoma,G2 Moderately differentiated,5.5,166,87,31,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,11,Stage I,NA,1.414147276,CNV_L,No,20.85,MSI-H,MSI-H,605,WT,Mutated,WT,Mutated,WT,3.49E-02,0,0,0,0,2.10E-17,1.77E-17,0,0,9.12E-19,1.19E-17,0,2.45E-02,5.44E-18,6.77E-20,2.37E-03,4.02E-18,1.66E-18,0,0,1.51E-02,9.18E-03,5.58E-03,2.14E-03,5.04E-20,1.35E-18,2.34E-03,1.37E-03,6.23E-18,2.99E-04,1.25E-02,1.11E-02,3.16E-17,5.13E-02,0.152476144,0,1.24E-02,3.15E-03,1.55E-02,0,0,4.88E-02,0,0,7.28E-02,0,4.28E-02,7.67E-03,0,0,1.06E-02,0,0.345744699,0,0.172960294,0,5.13E-02,0,0.143478492,4.80E-02,5.59E-02,16,0,244,0,0,0,0,86,0,0,69,0.79,Yes,No,0.110689746,-0.349973682,0.346445396,2.104449186,-0.25644425,-0.358640898,1.011673668,-0.676356199,0.862513819,-1.584755312,1.053743805,-1.272417748,2.435781627,-0.40816562,2505.531431,3522.469272,6028.000703,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Unifocal,0,0,0,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,None,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record,Siofor|Faxolet ER 75|Ketiplet|Bisocard,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,253|665|1045,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Unknown|Never|Never,Never|Never|Never,No|No|No,Yes|No|No,None|None|None,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,253.0|665.0|1045.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02978-b1,C3N-02978,Yes,b3,12,129C,CPT0244470003,Tumor,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-02979,C3N-02979,No,b2,6,130C,CPT0188100004,Tumor,No,61,Female,Endometrioid carcinoma,G3 Poorly differentiated,4,158,69,27,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,10,Stage I,NA,6.52E-04,CNV_L,No,30.64,MSI-H,MSI-H,1066,WT,Mutated,WT,Mutated,Mutated,0.186319434,3.23E-02,1.55E-02,0,0,5.86E-18,0,1.77E-02,6.83E-03,1.24E-02,4.67E-03,1.16E-03,2.49E-02,9.95E-19,5.09E-03,6.92E-03,2.33E-18,0,1.44E-17,1.20E-02,3.13E-02,3.85E-02,1.52E-03,8.79E-03,8.35E-20,0,1.25E-02,9.68E-20,0,2.76E-02,0.132744518,3.13E-02,0,0.193014788,0.327562554,7.38E-18,5.62E-02,3.46E-03,5.96E-02,1.32E-02,0,1.78E-02,0.105063395,0,0.168575072,7.18E-02,5.81E-02,0,0,4.96E-02,3.35E-02,0,4.23E-02,0.136629496,0.27830002,0,0,1.73E-03,0,0,2.32E-02,0,181,403,0,0,0,0,203,0,0,0,0.73,Yes,No,-1.558987383,-1.191964141,8.39E-02,0.199729184,-0.519301301,-1.31E-02,-0.282597715,-2.07108605,1.11361067,-1.13035857,-0.702183912,-0.756419985,7.45E-02,-1.467945044,3885.812031,5133.685775,9019.497805,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,0,0,4,0,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,"CK7 - negative, CK19 - negative, Chromogranine - negative, CD10 - negative, Synaptophizine - negative",NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record|Medical Record|Medical Record|Medical Record,Noliprol forte|Bisocard|Glucophage|vasilip|Fragmin|Citrafleet,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,393|647|976,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Never|Never|Never,Never|Never|Never,Yes|Yes|Yes,Yes|Yes|Yes,2|2|2,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,435.0|689.0|1018.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-02994,C3N-02994,No,b3,11,131N,CPT0248000003,Tumor,No,68,Female,Clear cell carcinoma,G3 Poorly differentiated,2.5,162,73,27,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,16,Stage I,NA,1.664379605,CNV_L,No,32.2,MSI-H,MSI-H,1321,Mutated,Mutated,WT,Mutated,Mutated,0.228347918,2.20E-02,5.80E-22,1.63E-18,0,1.59E-18,3.70E-02,1.28E-03,0,0,0,2.19E-03,3.72E-02,0,2.41E-03,1.58E-03,5.91E-20,4.35E-18,0,0,7.37E-02,6.10E-02,2.87E-02,0,6.14E-19,1.21E-02,6.61E-03,0,5.07E-18,8.17E-02,4.64E-02,7.29E-03,1.26E-02,0.151115485,0.10084028,0,7.34E-02,3.15E-03,7.66E-02,1.35E-03,0,5.75E-02,5.95E-02,0,0.108649589,2.04E-02,7.76E-02,0,6.94E-03,0,6.12E-02,7.71E-02,7.83E-02,0.100178654,0.272419956,0,3.05E-02,0,1.69E-02,0,3.13E-02,470,177,0,0,0,0,369,0,0,0,0,0.51,NA,NA,-2.131794543,0.996114937,-2.512408626,1.397748065,2.192912044,0.380419575,0.75742671,0.973177248,0.686184746,-0.674988569,0.54577056,-0.317470907,0.509482109,-1.552645943,3840.106201,5653.733119,9493.839321,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Fundus,NA,Unifocal,IHC staining not done,0,1,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Negative,Negative,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,Yes,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,1,EMA (+),NA,No,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record,No,NA,NA,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,337|725|980,Yes|Yes|Yes,Yes|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Never|Never|Never,Never|Never|Never,No|No|No,No|No|No,1|1|1,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,337.0|725.0|980.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-03005,C3N-03005,No,b2,5,129N,CPT0247940003,Tumor,No,>=90,Female,Endometrioid carcinoma,G2 Moderately differentiated,4,155,78,32,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,4,Stage I,NA,7.504663231,CNV_L,No,0,MSS,CNV_L,78,WT,Mutated,WT,WT,WT,0.136934637,6.63E-02,4.89E-03,0,0,3.28E-18,7.46E-02,9.11E-20,5.18E-03,2.82E-02,8.07E-19,3.44E-03,4.69E-02,0,1.15E-02,1.51E-02,0,1.45E-02,0,3.15E-02,2.90E-02,2.12E-02,2.06E-02,5.57E-03,3.12E-04,2.42E-04,0,5.78E-20,0,5.50E-03,1.89E-02,6.08E-02,0,3.47E-02,0.132437016,1.10E-19,7.85E-02,1.70E-02,9.54E-02,0,0,6.39E-02,9.01E-02,0,0.219648814,1.06E-02,4.97E-02,9.97E-03,0,7.07E-02,0,9.79E-03,9.54E-02,1.93E-02,0.208454493,5.24E-02,4.04E-02,0,3.38E-02,0,2.59E-02,21,27,0,0,0,0,26,0,0,0,0,0.31,NA,NA,1.09266565,-0.553515684,0.556683753,0.378119839,1.156744063,-1.497099808,0.488121317,0.740961007,0.606740987,0.377499539,0.47328784,1.241677203,-0.114117071,-0.541184904,5460.544855,5773.711888,11234.25674,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,4 or more,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Bisocard|Hygroton|Polocard,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Deceased,450|734|857,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Never|Never|Never,Never|Never|Never,Yes|Yes|Yes,No|No|No,4 or more|4 or more|4 or more,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,450.0|734.0|n/a,n/a|n/a|Respiratory Disease,n/a|n/a|898.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-03415,C3N-03415,No,b2,7,130N,CPT0247910003,Tumor,No,85,Female,Endometrioid carcinoma,G3 Poorly differentiated,4.8,150,52,23,Present,=50% myometrial invasion,Seventh Edition (2010),pT1b (FIGO IB),pN0,5,Stage I,NA,0.146408992,CNV_L,No,32.41,MSI-H,MSI-H,6659,Mutated,Mutated,Mutated,Mutated,WT,0.209530632,1.80E-02,1.15E-02,0,7.17E-19,1.54E-18,7.86E-20,1.08E-02,5.20E-03,2.23E-02,0,1.85E-03,3.77E-02,0,1.62E-02,2.22E-19,1.43E-18,6.92E-18,0,7.01E-04,3.68E-02,1.76E-02,3.25E-02,5.86E-03,0,1.00E-18,3.88E-03,1.98E-18,0,1.65E-02,7.34E-02,2.24E-02,7.77E-03,0.151379251,0.314025643,0,5.47E-02,3.71E-18,5.47E-02,6.94E-03,0,3.52E-02,0.12580074,0,0.118640627,9.70E-02,5.93E-02,0,2.55E-02,0,6.34E-02,0,0,6.95E-02,0.268245225,1.69E-02,0,0,0.101829592,0,1.16E-02,161,314,0,0,0,0,0,0,1939,2445,1221,0.23,NA,NA,-1.136963415,-1.024358542,-2.286263556,1.218158501,-1.23439774,5.22E-02,-2.15E-02,-0.230024824,1.608784387,-2.005919563,-0.474275759,-0.900573473,1.600195685,-1.523080234,2384.810301,4565.22009,6950.030391,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Unifocal,IHC staining not done,0,3,IHC staining not done,0,0,0,0,cM0,R0: No residual tumor,Positive : % Not available,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,Unknown,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Enarenal|Sustonit|Signopam,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Deceased,411|712|870,Yes|Yes|Yes,Yes|Yes|Yes,No|No|No,Tumor Free|Tumor Free|Tumor Free,Never|Never|Never,Never|Never|Never,Never|Never|Never,Yes|Yes|Yes,No|No|No,Unknown|Unknown|Unknown,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,411.0|712.0|n/a,n/a|n/a|Respiratory Disease,n/a|n/a|1047.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-03417,C3N-03417,No,b4,13,128C,CPT0247880003,Tumor,No,67,Female,Endometrioid carcinoma,G1 Well differentiated,2.7,165,83,30.49,Present,<50% myometrial invasion,Seventh Edition (2010),pT1a (FIGO IA),pN0,5,Stage I,NA,1.04E-02,CNV_L,No,0.64,MSS,CNV_L,60,WT,Mutated,Mutated,Mutated,Mutated,3.73E-02,5.10E-03,1.87E-03,0,0,1.32E-17,1.41E-18,3.53E-03,4.49E-20,1.78E-02,0,1.77E-18,2.36E-02,0,0,0,0,0,6.46E-18,5.80E-03,1.34E-19,9.26E-19,1.96E-03,0,0,1.41E-17,1.39E-03,0,3.10E-18,1.63E-02,3.06E-02,5.60E-03,0,6.02E-02,0.289266356,2.25E-18,3.40E-03,0,3.40E-03,5.66E-02,0,9.17E-02,0.115563316,0,0.246878938,3.77E-02,7.77E-02,0,0,6.79E-02,0,0,0.112992327,6.16E-02,8.37E-02,1.10E-02,0,0,2.18E-02,1.49E-02,0,22,21,0,14,0,0,0,0,0,0,0,0.77,NA,NA,-0.684400881,0.561581065,-1.102347356,-8.92E-02,0.222665419,0.924786309,-1.105861496,-0.786586684,0.280656974,-0.713629763,-1.262334267,-1.974988541,1.698376833,0.241199831,2608.1265,3031.213167,5639.339667,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Posterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Positive : % Not available,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Loss of expression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Unknown,3,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,Medical Record|Medical Record|Medical Record,Yes,Medical Record|Medical Record|Medical Record,Bisoratio|Protevasc|Acard,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Living,346|710|1103,Yes|Yes|Yes,No|No|No,No|No|No,Tumor Free|Tumor Free|Tumor Free,Unknown|Unknown|Never,Never|Never|Never,Never|Never|Never,Yes|Yes|Yes,No|No|No,3|3|3,No|No|No,Complete Remission|Complete Remission|Complete Remission,Complete Remission|Complete Remission|n/a,n/a|n/a|Complete Remission,No|No|No,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,346.0|710.0|1103.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3N-03767,C3N-03767,No,b2,5,128N,CPT0247970003,Tumor,No,66,Female,Serous carcinoma,G3 Poorly differentiated,13,158,62,24,Present,=50% myometrial invasion,Seventh Edition (2010),pT2 (FIGO II),pN0,13,Stage II,NA,34.44230553,CNV_H,No,1.01,MSS,CNV_H,66,WT,WT,WT,WT,WT,7.67E-02,1.43E-02,0,4.98E-03,3.27E-19,8.11E-04,3.17E-02,5.32E-04,0,7.01E-20,3.05E-19,9.28E-03,0,1.42E-03,0,1.81E-02,0,1.06E-17,0,9.18E-03,2.56E-02,1.12E-02,1.70E-02,1.08E-02,2.18E-18,1.78E-03,5.02E-03,3.23E-19,0,3.02E-02,2.38E-02,9.99E-03,2.03E-18,4.92E-02,0.138446294,8.13E-19,3.50E-02,9.04E-03,4.40E-02,2.81E-02,0,2.94E-02,0.131642052,0,0,0,4.53E-03,0.100298365,9.25E-02,2.59E-02,0,2.34E-03,0.206982853,0,0.242741027,0,8.51E-02,0,1.92E-02,4.46E-03,2.68E-02,20,22,0,0,0,0,0,0,0,21,0,0.45,NA,NA,-1.129793055,1.027499579,-1.768589342,1.244398301,-1.277384025,0.623079578,-0.722419304,-0.979551296,-0.566171478,-0.655647341,-0.817136634,-0.858177651,1.45056114,-1.726708429,2578.671466,3457.536356,6036.207822,Not Examined,Not identified,Margins uninvolved by invasive carcinoma,NA,Caucasian,Poland,Anterior endometrium,NA,Unifocal,IHC staining not done,0,0,IHC staining not done,0,0,IHC staining not done,0,cM0,R0: No residual tumor,Negative,Negative,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,No,Cannot be determined,No,Postmenopausal: greater than 12 months since LMP with no prior Oophorectomy OR Prior bilateral oophorectomy,Never,2,NA,NA,No,Lifelong non-drinker,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,NA,NA,NA,NA,No or minimal exposure to secondhand smoke,NA,No,NA,NA,NA,NA,NA,NA,Yes,1,12 Months|24 Months|36 Months,No|No|No,Living|Living|Deceased,491|721|897,Yes|Yes|Yes,Yes|Yes|Yes,No|No|No,With Tumor|With Tumor|With Tumor,Never|Never|Never,Never|Never|Never,Never|Never|Never,No|No|No,No|No|No,2|2|2,No|No|No,Persistent Disease|Persistent Disease|Persistent Disease,Persistent Disease|Persistent Disease|n/a,n/a|n/a|Persistent Disease,Yes|Yes|Yes,Distant Metastasis|Distant Metastasis|Distant Metastasis,Lung|Lung|Lung,491.0|491.0|491.0,No|No|No,No|No|No,No|Yes|Yes,No|No|No,491.0|721.0|n/a,n/a|n/a|Malignant Neoplasm,n/a|n/a|1002.0,n/a|n/a|n/a,n/a|n/a|n/a,n/a|n/a|n/a +C3L-00935-A,C3L-00935,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,8.87E-02,0,0,0,4.75E-18,0,4.89E-18,9.67E-03,1.09E-03,9.58E-03,5.63E-18,0,1.54E-02,4.97E-03,5.81E-03,0.120966395,0,0.504130901,1.83E-02,0.409030325,0,0,9.24E-04,0,0,0,0,0,0,0,0,7.02E-18,1.26E-17,5.67E-03,9.89E-02,0,4.60E-03,0.319778855,0.324382239,8.84E-02,0,3.65E-02,4.72E-02,0,0.148954717,0,4.14E-02,0,5.57E-02,0,5.62E-02,0,9.39E-02,4.29E-02,0.144343921,3.27E-02,0,0.211995968,0,0,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.211046408,-1.163818206,0.20088871,-1.271131044,0.656300892,-0.905376669,-0.302948854,-1.066028656,-2.124537065,0.943415918,-0.365934904,0.821306291,-1.985280952,-0.355157133,6048.885334,4277.403784,10326.28912,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-01277-A,C3L-01277,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,3.26E-02,0,6.68E-19,3.42E-19,9.56E-20,6.75E-03,0,1.71E-02,8.33E-03,2.22E-19,2.12E-18,0,1.43E-02,2.30E-03,6.76E-19,0.210487924,1.36E-19,0.732908677,2.56E-02,0.652074717,0,4.40E-03,2.38E-03,1.20E-02,0,6.41E-18,0,0,7.02E-18,3.13E-02,1.88E-17,3.81E-18,2.09E-20,0,4.40E-02,0,1.36E-02,0.489786717,0.503358739,8.42E-02,0,1.23E-02,1.69E-02,0,0.288982746,0,6.66E-03,0,4.17E-02,0,5.03E-02,0,0,3.53E-03,0.248263085,0,7.70E-03,0.239400582,0,0,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-1.414135341,-1.020306365,-0.16799745,-1.532624523,-1.052620735,-0.863345831,-1.625708517,-1.829445817,-0.793469855,1.527938946,-1.844476202,0.504574412,-0.739065574,-1.986846148,6711.035705,4219.232716,10930.26842,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-01639-A,C3L-01639,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,9.51E-02,1.27E-18,2.41E-18,6.70E-03,1.27E-17,2.19E-03,6.43E-03,4.98E-03,6.63E-03,1.34E-02,1.43E-18,0,1.03E-02,9.42E-03,1.04E-02,0.140680315,5.28E-03,0.538364102,1.73E-02,0.445838095,0,0,5.73E-03,3.55E-20,2.21E-18,0,7.79E-19,0,4.61E-18,7.45E-03,0,3.96E-18,6.94E-19,1.03E-03,2.07E-02,2.70E-03,1.49E-02,0.352513988,0.367374104,7.97E-02,0,6.61E-02,5.99E-02,0,0.184571918,0,4.02E-02,0,2.33E-02,0,0.105593768,1.80E-03,5.71E-03,4.35E-02,0.177980921,3.66E-02,0,9.61E-02,6.56E-02,0,1.32E-02,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.253623114,0.326370073,0.903270377,-1.10153486,-0.29478359,-0.297765172,0.587509746,-0.290579393,-2.813528775,1.350366552,0.625322857,1.027936076,-1.373760636,0.452931332,6912.831464,5165.054101,12077.88557,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-01967-A,C3L-01967,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0,0,2.51E-18,0,0,0,0,1.75E-02,0,0,0,1.55E-17,1.89E-02,3.71E-03,0,0.194065816,1.68E-18,0.653919656,5.87E-02,0.727097981,4.03E-18,0,0,0,0,1.06E-17,0,0,0,0,2.49E-17,2.26E-18,5.04E-18,0,3.20E-02,5.93E-19,1.09E-17,0.435238368,0.435238368,2.20E-02,0,3.93E-03,5.64E-02,0,0.235822388,0,2.54E-02,0,6.07E-02,0,5.92E-02,0,0,7.13E-03,0.213152393,0,0,0.316206686,0,0,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.498955371,-1.794032951,-0.437990693,-1.550438395,-0.501700787,-1.504175763,-1.683139964,-1.677800851,-2.247384885,1.092535941,-1.739202793,5.31E-02,-0.63537576,-1.414576593,6344.945644,3855.2529,10200.19854,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-02121-A,C3L-02121,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,3.60E-02,0,7.87E-18,0,0,0,1.11E-17,4.01E-03,6.23E-03,1.65E-19,3.88E-18,1.68E-17,3.03E-02,9.22E-03,0,0.198581286,6.29E-18,0.600784169,3.40E-02,0.726487652,9.79E-19,9.63E-04,0,1.08E-03,1.29E-18,0,4.16E-18,3.44E-18,7.52E-18,2.15E-19,1.80E-17,1.06E-18,4.55E-18,1.25E-20,3.59E-02,4.92E-18,4.87E-03,0.410394644,0.415266171,0,0,0,2.19E-02,0,8.17E-02,0,0,0,4.96E-02,0,3.65E-02,4.16E-02,0,0,0.286802129,0,1.11E-02,0.470840163,0,0,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-1.029138117,-2.283354488,0.784495524,-1.626815622,-0.568082443,-2.144657328,-2.230521597,-2.521069728,-0.39842562,1.332206765,-2.33375145,0.33630669,-0.968764978,-2.306827196,6867.623231,4085.415341,10953.03857,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-02216-A,C3L-02216,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,6.76E-02,0,0,2.40E-18,2.13E-17,0,3.95E-18,1.33E-02,4.72E-03,2.61E-03,0,4.06E-18,1.75E-02,4.72E-03,2.93E-03,9.29E-02,0,0.616006359,1.92E-03,0.564808115,0,3.11E-03,2.45E-03,5.75E-22,0,4.78E-18,2.62E-18,3.15E-04,0,3.26E-02,5.49E-18,7.71E-19,0,0,2.06E-03,1.63E-19,5.31E-03,0.361027326,0.366338058,8.05E-02,0,3.61E-02,4.47E-02,0,0.205984969,0,2.51E-02,0,0,0,6.05E-02,6.16E-02,0,1.50E-02,0.224371107,0,3.29E-03,0.217911571,1.62E-02,0,8.61E-03,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.129353198,-0.321850488,0.849211729,-1.218297996,-0.404627678,-0.554390972,0.287246403,-0.523223047,-2.125387181,1.425969954,0.182025103,0.766235421,-1.339316658,0.227294681,7125.299823,4777.841893,11903.14172,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-02347-A,C3L-02347,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,5.44E-02,0,5.63E-18,2.35E-18,0,0,0,1.15E-02,4.17E-18,2.35E-19,2.26E-18,0,1.58E-02,6.17E-03,1.44E-19,0.251570738,8.02E-19,0.663621454,2.28E-02,0.841734884,3.27E-19,0,0,2.99E-19,0,0,0,0,2.17E-18,2.84E-19,0,7.88E-18,2.50E-17,0,2.51E-02,0,5.28E-18,0.471753809,0.471753809,0,0,9.32E-03,5.91E-02,0,0.185742456,0,0,0,3.04E-02,0,4.88E-02,1.08E-02,0,1.08E-02,0.30523825,4.07E-02,2.76E-03,0.288122833,0,0,8.40E-03,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-1.248399119,-2.079062633,-0.473255663,-1.453244388,-0.26348033,-1.617547424,-1.419313665,-1.297005685,-2.21004854,1.301062732,-1.502534757,0.530110014,-1.494404074,-1.797755369,6770.680361,4164.60188,10935.28224,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-02353-A,C3L-02353,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,2.39E-03,0,2.11E-21,3.39E-19,0,0,2.41E-17,6.05E-03,6.91E-19,3.70E-03,4.66E-18,0,7.02E-03,4.58E-03,2.03E-19,0.196339531,7.09E-18,0.619811332,2.17E-02,0.613034072,2.35E-19,0,0,8.56E-19,0,0,0,0,0,0,1.38E-17,0,0,0,2.30E-02,2.79E-18,6.05E-18,0.417245935,0.417245935,3.46E-02,0,2.64E-02,8.18E-02,0,0.228455458,0,1.61E-02,0,1.36E-02,0,5.06E-02,5.91E-03,0,5.70E-03,0.200181509,0,1.56E-02,0.321051161,0,0,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.271352996,-0.967337914,0.47433009,-1.450767193,0.134565201,-0.845521523,-0.713857878,-0.756074638,-2.413510083,1.286906112,-0.647963762,0.673471594,-0.601734164,-0.514545962,6425.985404,3846.190997,10272.1764,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-02408-A,C3L-02408,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.131210134,0,0,0,1.98E-17,0,3.07E-03,1.26E-02,1.73E-02,8.71E-03,9.13E-18,0,1.64E-02,0,1.16E-02,0.133147777,9.13E-03,0.612616439,5.34E-02,0.766076189,1.35E-03,4.38E-03,1.16E-02,5.25E-03,1.07E-17,9.38E-03,0,1.94E-04,1.33E-17,0.110667849,4.24E-17,4.45E-20,0,8.63E-19,8.10E-02,7.44E-19,3.61E-02,0.37711775,0.413245881,2.40E-02,0,5.48E-02,7.51E-02,0,0.175123362,0,7.85E-03,0,5.31E-02,0,2.81E-02,1.62E-02,0,3.42E-03,0.236818568,0,4.88E-02,0.220394789,2.98E-02,0,2.64E-02,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.933239197,0.913199637,1.178173157,-0.830313519,-0.12915265,0.646966436,0.94913735,-0.199865835,-1.088330724,1.888357198,0.62417164,1.730456151,-1.551065165,-0.566461594,7925.918641,6126.937728,14052.85637,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-02409-A,C3L-02409,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,3.27E-02,0,0,0,0,1.71E-17,6.17E-20,0,0,2.90E-18,2.31E-17,7.11E-18,1.52E-03,0,2.66E-03,5.09E-02,5.64E-18,0.322699883,0,0.383590369,9.21E-21,1.38E-02,1.48E-03,0,1.84E-18,0,0,0,5.15E-18,0,0,0,8.37E-18,0,2.57E-02,1.28E-18,1.77E-03,0.187915174,0.189685599,2.49E-02,0,7.29E-02,3.27E-02,0,0.159441905,0,0,0,2.36E-02,0,3.64E-02,0,0.271801413,8.48E-03,0.229752271,0,1.25E-02,0,0.105419365,0,2.21E-02,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.9557728,0.548289566,3.41E-04,1.81E-02,-0.345797202,0.519290737,0.860105774,1.302085624,-0.522851349,1.325185321,0.993419738,1.372261072,-0.905048667,1.058334661,6222.880071,5060.837371,11283.71744,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-02412-A,C3L-02412,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.215739227,0,0,0,7.75E-18,2.29E-02,3.15E-02,3.75E-03,0,1.45E-02,0,0,5.11E-03,0,1.83E-02,0.131728147,1.69E-02,0.526818772,2.43E-02,0.75770873,0,8.49E-03,3.65E-03,2.12E-03,1.55E-17,1.34E-02,0,4.06E-03,0,2.04E-02,1.28E-18,0,0,1.20E-17,0,0,3.65E-02,0.332106794,0.368611615,0,0,4.10E-02,6.86E-02,0,0.236196429,0,2.53E-03,0,1.36E-02,0,9.36E-02,1.22E-02,0,6.22E-04,0.261489771,0,5.20E-02,0.136986379,3.84E-02,7.78E-03,3.50E-02,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.391845651,1.699940261,-0.116827,-0.776342791,0.14047024,0.94591908,1.106123198,1.513517672,-0.763164399,2.054977063,1.063772836,2.407469148,-1.577275359,-0.439496296,7712.295621,6740.407053,14452.70267,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-02468-A,C3L-02468,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,4.40E-02,0,0,1.50E-19,2.01E-19,9.38E-18,0,6.12E-03,6.12E-03,3.20E-19,1.01E-18,1.59E-20,1.22E-02,8.23E-03,7.28E-20,6.92E-02,0,0.641342513,1.25E-02,0.56595538,1.10E-18,4.45E-03,1.46E-03,1.39E-18,0,0,0,0,0,1.09E-02,4.26E-18,0,0,2.44E-02,4.23E-02,5.42E-20,4.08E-03,0.358160588,0.362237931,6.26E-03,0,3.40E-03,6.08E-02,0,0.212626096,0,4.29E-02,0,0,3.38E-02,6.22E-02,2.67E-02,0,6.89E-03,0.208514434,0,8.91E-03,0.327089814,0,0,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.140236289,-2.88716034,-0.996508995,-1.369861021,-0.904218543,-2.590928371,-2.028762638,-1.785443699,-1.00904764,1.762117684,-2.0353135,0.610363391,-0.662719021,-1.837209585,6558.709881,3764.485072,10323.19495,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-02557-A,C3L-02557,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,7.24E-02,0,0,0,4.43E-19,0,0,1.66E-02,5.37E-02,3.97E-02,0,0,2.43E-02,0,5.30E-03,0.103708401,0,0.689665295,9.42E-03,0.501280037,3.24E-03,5.47E-03,1.43E-02,2.43E-03,0,0,0,1.10E-20,0,5.43E-02,1.78E-17,0,0,0,7.89E-02,1.47E-02,4.31E-02,0.405916254,0.449001326,0,0,4.09E-02,8.16E-02,0,0.293708179,0,1.05E-03,0,6.00E-02,0,7.65E-02,0,2.37E-02,1.33E-02,0.184846121,0,3.90E-02,0.178316573,0,0,7.03E-03,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.151016253,-0.413968182,-0.54664953,-1.436754293,-0.678421068,-0.359791585,-0.688589313,-1.235313253,-1.042289823,1.841018131,-0.756341535,0.531813177,-1.049237752,-0.438256446,6770.994541,5047.086005,11818.08055,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3L-02602-A,C3L-02602,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,3.99E-02,0,1.01E-17,0,0,3.78E-18,0,6.85E-03,2.87E-19,4.29E-19,9.01E-18,0,2.69E-02,7.70E-03,1.91E-20,0.168002798,0,0.596503979,2.34E-02,0.658958354,2.17E-18,0,0,3.12E-19,0,2.74E-17,0,1.33E-18,4.09E-18,9.92E-19,0,0,0,7.79E-18,2.69E-02,1.00E-19,2.37E-17,0.39488576,0.39488576,3.08E-02,0,3.81E-03,8.51E-02,0,0.224482124,0,3.42E-03,0,0,0,3.26E-02,1.22E-02,0,9.14E-03,0.218299057,3.49E-04,3.13E-03,0.345976918,0,3.07E-02,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-1.05E-03,-1.691415127,0.425786212,-1.40327774,-0.337226582,-2.017029214,-1.742841389,-1.238365244,-2.713352836,1.463258594,-1.683314273,0.723022501,-1.340393444,-0.795094283,7044.501377,4183.202184,11227.70356,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-00520-A,C3N-00520,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,3.25E-02,0,1.82E-20,3.60E-18,8.99E-18,0,9.51E-03,0,0,4.08E-19,7.26E-18,2.38E-18,0,0,3.03E-03,5.37E-03,3.79E-19,0.237411611,2.19E-18,0.197726532,1.12E-19,5.33E-03,3.27E-04,0,2.35E-18,0,8.43E-18,4.82E-19,0,3.53E-03,0,6.48E-03,0,0,2.61E-18,2.95E-03,2.02E-03,0.122308489,0.124328306,2.97E-02,0,0,2.12E-02,0,0.384109239,0,5.95E-02,0,0,0,1.76E-02,4.65E-02,0,3.33E-03,0.207351134,0.108566413,3.42E-02,5.56E-02,3.24E-02,0,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,3.504331272,-0.178460747,-0.242888136,-1.144597295,-1.378702931,-0.104992313,-0.682985158,-0.109862444,-0.900703564,1.569574495,-0.680011241,0.191760782,-1.240880903,1.242117843,5840.467476,3924.20137,9764.668846,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-00859-A,C3N-00859,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.41E-02,2.44E-03,0,5.55E-18,0,2.08E-18,2.28E-02,2.76E-19,3.41E-18,0,9.71E-19,4.00E-03,6.01E-04,1.09E-18,0,0,4.01E-03,1.39E-02,0,1.90E-02,0,1.55E-03,3.72E-04,4.72E-03,6.62E-18,0,2.52E-03,0,8.03E-20,8.13E-03,2.75E-02,3.47E-03,4.18E-18,5.09E-02,5.70E-02,0,7.45E-03,9.41E-03,1.69E-02,0,0,5.48E-02,6.99E-02,0,0.12977877,0,0,3.22E-02,1.28E-03,0,3.68E-02,0,0.185643271,0,0.345265235,0,7.03E-02,0,1.48E-02,3.14E-02,2.78E-02,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.465643345,1.564356068,0.956532568,1.233825599,-0.479072708,0.80443949,-0.785553003,2.230841656,0.570570382,-0.200093478,-0.626182932,-0.287049877,0.97846244,-0.554310802,3038.923669,2644.370039,5683.293707,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-00872-A,C3N-00872,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.177926548,0,0,4.35E-19,0,2.36E-18,4.61E-02,1.59E-02,8.12E-02,7.17E-02,4.59E-03,3.21E-18,1.55E-02,0,1.46E-02,7.39E-02,7.07E-04,0.524513105,3.22E-03,0.437779233,1.83E-02,2.14E-02,2.07E-02,6.91E-03,6.79E-18,1.61E-03,0,1.05E-03,4.56E-19,1.73E-02,8.81E-18,1.46E-03,0,1.82E-17,6.40E-02,0,8.30E-02,0.307491693,0.390445033,2.31E-02,0,5.50E-02,0.149473131,0,0.215750488,0,1.26E-02,0,4.99E-02,0,8.63E-02,0,1.62E-04,4.00E-02,0.207097987,3.59E-04,6.61E-04,1.61E-02,0.132943273,0,1.05E-02,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.377115669,-0.278664379,0.248138947,-0.697537837,0.103318115,-0.869483008,0.51153038,-0.366900549,-1.082567936,1.870398552,0.314260087,1.989293078,-1.233601392,0.555595171,7832.470038,6278.029107,14110.49914,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-01344-A,C3N-01344,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.102277861,9.95E-19,0,0,5.65E-19,0,0,0,7.42E-18,0,2.92E-19,7.67E-19,0,2.12E-18,2.19E-20,0,2.71E-18,0,6.62E-19,1.64E-02,3.31E-19,1.11E-02,1.99E-03,0,0,0,1.13E-19,0,5.27E-18,0,2.35E-02,3.71E-03,0,7.21E-02,1.39E-03,1.14E-18,1.15E-17,0,1.15E-17,4.42E-02,0,3.47E-02,1.21E-02,0,0.11682117,0,9.91E-02,0,1.86E-02,0,7.62E-02,0,8.96E-02,4.66E-03,0.200680109,0,0.221806886,2.34E-02,0,0,5.81E-02,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.762226593,0.349684456,-0.396812251,0.137712717,2.940347545,0.233443073,0.117049522,1.38648037,-0.259023813,-0.197161799,0.244119482,-0.30886802,0.267114696,1.068768281,3031.933481,3776.546198,6808.479679,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-01525-A,C3N-01525,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.255764541,0,0,1.25E-17,8.83E-18,6.39E-21,3.67E-02,5.06E-03,7.04E-18,7.64E-03,0,2.09E-18,9.16E-03,4.97E-03,9.95E-03,9.82E-02,3.28E-03,0.400281979,9.36E-03,0.622992964,0,1.08E-02,5.67E-03,1.11E-02,1.84E-17,5.31E-02,0,1.02E-02,2.61E-18,2.39E-03,0,0,0,0,0,8.84E-20,5.84E-02,0.262314399,0.320723703,0,0,3.69E-02,0.104719513,0,0.124913255,0,3.22E-02,0,0,0,5.99E-02,0.120359669,0,6.11E-03,0.198008067,0,3.18E-02,0,0.232313931,0,5.28E-02,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,2.033936923,2.651293378,0.130626246,-0.888300351,0.121750323,1.882601204,1.358664058,2.030387319,0.629703017,1.968475431,1.398238035,1.877116406,-0.67029527,-0.45024582,7407.103417,7035.151955,14442.25537,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-01526-A,C3N-01526,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,5.86E-02,0,0,6.55E-18,1.78E-17,3.39E-02,2.15E-02,1.39E-03,2.48E-18,0,0,0,4.93E-03,1.25E-02,5.72E-04,7.17E-02,0,0.382016661,6.23E-03,0.513474028,0,8.67E-04,3.77E-05,4.35E-03,6.85E-18,0,8.13E-18,0,1.23E-19,2.88E-02,0,0,3.80E-18,1.94E-20,0,0,3.28E-03,0.229137087,0.232417684,1.63E-02,0,6.06E-02,0.100744808,0,0.144147398,0,5.08E-02,0,1.50E-02,0,3.89E-02,7.96E-02,0,1.07E-02,0.174271138,1.76E-02,3.91E-03,0.252950634,3.44E-02,0,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.198583945,2.092040656,0.754697088,-1.20E-02,-0.595248117,1.231009441,-0.209081688,2.185977047,-0.587437631,1.604530189,-0.158902509,1.487404635,-0.744430111,-0.263525223,6428.034564,4843.35425,11271.38881,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-01761-A,C3N-01761,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,5.88E-02,0,1.14E-17,0,7.45E-19,3.44E-18,2.06E-17,6.86E-03,0,5.95E-19,2.40E-17,1.23E-17,1.56E-02,1.12E-02,0,0.185705141,8.74E-18,0.70847269,2.13E-02,0.762720694,0,0,3.99E-03,0,0,7.45E-18,0,1.41E-19,0,2.77E-03,2.69E-17,6.24E-18,0,0,2.75E-02,0,1.14E-17,0.458361628,0.458361628,4.18E-03,0,2.71E-03,9.25E-02,0,0.163461823,0,3.52E-02,0,0,0,6.84E-02,2.17E-02,0,7.19E-03,0.229998202,0,6.93E-03,0.347617108,0,0,2.02E-02,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.86886259,-1.138641717,0.287104266,-0.870810758,-0.666947676,-0.992998113,-0.937120032,-1.07122901,-1.374719452,1.629555029,-0.990817573,0.911391458,-0.68118662,-1.65385842,6960.593486,4245.227399,11205.82088,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-01765-A,C3N-01765,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.385709251,6.09E-03,1.56E-02,3.96E-02,3.45E-19,1.13E-17,0.132035182,9.77E-03,0.176715243,0.18409375,8.30E-02,1.09E-20,1.04E-02,1.88E-02,2.46E-02,0.145543369,2.34E-03,0.528764457,3.27E-02,0.747813912,2.22E-02,1.99E-02,2.12E-02,1.58E-02,0,4.84E-02,7.60E-19,0,6.26E-18,1.26E-02,3.22E-02,2.74E-03,1.00E-18,1.24E-17,0.116741345,1.01E-17,0.197389264,0.339351587,0.536740851,2.65E-02,6.61E-03,1.46E-02,0.15082551,0,0.167463768,0,5.28E-02,0,9.98E-02,0,6.23E-03,4.94E-02,0,4.97E-02,0.227961499,4.90E-03,0,0.141955202,0,0,1.41E-03,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.455078744,-0.711693628,0.125925848,-1.369280232,1.206095225,-0.823642015,0.17434572,0.839653304,-0.973497197,1.438362627,8.09E-02,3.074014285,-1.798089975,-0.327055551,8322.649314,8591.06139,16913.7107,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +C3N-01830-A,C3N-01830,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.206049786,0,0,6.52E-18,9.26E-18,0,3.82E-02,1.10E-03,1.81E-18,2.80E-02,0,0,6.12E-03,1.32E-02,9.32E-03,9.07E-02,0,0.312759043,7.72E-03,0.532419328,1.98E-04,1.29E-02,5.02E-03,2.36E-03,8.98E-18,7.21E-02,0,2.59E-03,2.05E-17,9.62E-03,8.70E-03,1.32E-18,1.08E-18,3.18E-20,1.88E-03,0,5.77E-02,0.20356628,0.261302494,1.37E-02,0,4.02E-02,7.65E-02,0,0.148369365,0,3.88E-02,0,5.63E-02,0,6.91E-02,0.171119695,0,1.79E-02,0.192388542,0,4.98E-02,0.12316596,0,0,2.64E-03,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,2.419634611,1.876637456,0.649845366,-0.370041125,0.894831163,1.161911614,0.627432791,2.370514834,0.107487926,1.367786114,0.628101077,1.273370183,-1.308397785,-0.25367492,7151.535829,6874.816632,14026.35246,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA 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+C3N-02249-A,C3N-02249,No,NA,NA,NA,NA,Adjacent_normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.39E-02,0,0,1.37E-18,0,0,5.66E-18,3.93E-03,0,4.36E-19,1.26E-17,0,8.49E-03,1.49E-03,0,0.245939725,0,0.653338677,2.35E-02,0.58301948,1.59E-18,0,1.69E-03,1.83E-18,0,3.39E-17,0,0,0,2.95E-18,1.02E-17,7.83E-18,0,1.24E-18,2.21E-02,3.09E-19,2.49E-17,0.461550321,0.461550321,7.48E-02,0,2.44E-03,3.39E-02,0,0.20711663,0,0,0,4.48E-02,0,8.92E-02,5.42E-03,0,0,0.183739041,0,1.73E-02,0.341239947,0,0,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-3.30E-02,-0.713369181,0.827332684,-1.171545177,-0.566017522,-0.554248023,-0.507234302,-1.22575424,-2.048022745,1.602198941,-0.517442781,-0.10510676,-0.907217907,-1.378538017,6705.846898,3992.943045,10698.78994,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA 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+NX036,NX036,No,b2,7,129N,CPT0313490002,Enriched_Normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +NX037,NX037,No,b4,16,130C,CPT0313420007,Enriched_Normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +NX038,NX038,No,b2,6,131C,CPT0313420004,Enriched_Normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA diff --git a/examples/datasets/Dou-ucec-discovery.csv b/examples/datasets/Dou-ucec-discovery.csv new file mode 100644 index 00000000..c99b6b34 --- /dev/null +++ b/examples/datasets/Dou-ucec-discovery.csv @@ -0,0 +1,154 @@ +idx,Proteomics_Participant_ID,Case_excluded,Proteomics_TMT_batch,Proteomics_TMT_plex,Proteomics_TMT_channel,Proteomics_Parent_Sample_IDs,Proteomics_Aliquot_ID,Proteomics_Tumor_Normal,Proteomics_OCT,Country,Histologic_Grade_FIGO,Myometrial_invasion_Specify,Histologic_type,Treatment_naive,Tumor_purity,Path_Stage_Primary_Tumor-pT,Path_Stage_Reg_Lymph_Nodes-pN,Clin_Stage_Dist_Mets-cM,Path_Stage_Dist_Mets-pM,tumor_Stage-Pathological,FIGO_stage,LVSI,BMI,Age,Diabetes,Race,Ethnicity,Gender,Tumor_Site,Tumor_Site_Other,Tumor_Focality,Tumor_Size_cm,Estrogen_Receptor,Estrogen_Receptor_%,Progesterone_Receptor,Progesterone_Receptor_%,MLH1,MLH2,MSH6,PMS2,p53,Other_IHC_specify,MLH1_Promoter_Hypermethylation,Num_full_term_pregnancies,EPIC_Bcells,EPIC_CAFs,EPIC_CD4_Tcells,EPIC_CD8_Tcells,EPIC_Endothelial,EPIC_Macrophages,EPIC_NKcells,EPIC_otherCells,CIBERSORT_B _cells _naive,CIBERSORT_B _cells _memory,CIBERSORT_Plasma _cells,CIBERSORT_T _cells _CD8,CIBERSORT_T _cells _CD4 _naive,CIBERSORT_T _cells _CD4 _memory _resting,CIBERSORT_T _cells _CD4 _memory _activated,CIBERSORT_T _cells _follicular _helper,CIBERSORT_T _cells _regulatory _(Tregs),CIBERSORT_T _cells _gamma _delta,CIBERSORT_NK _cells _resting,CIBERSORT_NK _cells _activated,CIBERSORT_Monocytes,CIBERSORT_Macrophages _M0,CIBERSORT_Macrophages _M1,CIBERSORT_Macrophages _M2,CIBERSORT_Dendritic _cells _resting,CIBERSORT_Dendritic _cells _activated,CIBERSORT_Mast _cells _resting,CIBERSORT_Mast _cells _activated,CIBERSORT_Eosinophils,CIBERSORT_Neutrophils,CIBERSORT_Absolute _score,ESTIMATE_StromalScore,ESTIMATE_ImmuneScore,ESTIMATE_ESTIMATEScore,Stemness_score,ER_ESR1,PR_PGR,Pathway_activity_EGFR,Pathway_activity_Hypoxia,Pathway_activity_JAK.STAT,Pathway_activity_MAPK,Pathway_activity_NFkB,Pathway_activity_PI3K,Pathway_activity_TGFb,Pathway_activity_TNFa,Pathway_activity_Trail,Pathway_activity_VEGF,Pathway_activity_p53,TP53_ATM,TP53_CHEK2,TP53_MDM4,TP53_RPS6KA3,TP53_TP53,TP53_pathway,PI3K_AKT1,PI3K_AKT2,PI3K_AKT3,PI3K_DEPDC5,PI3K_DEPTOR,PI3K_INPP4B,PI3K_MAPKAP1,PI3K_MLST8,PI3K_MTOR,PI3K_NPRL2,PI3K_NPRL3,PI3K_PDK1,PI3K_PIK3CA,PI3K_PIK3CB,PI3K_PIK3R1,PI3K_PIK3R2,PI3K_PPP2R1A,PI3K_PTEN,PI3K_RHEB,PI3K_RICTOR,PI3K_RPS6,PI3K_RPS6KB1,PI3K_RPTOR,PI3K_STK11,PI3K_TSC1,PI3K_TSC2,PI3K_pathway,HRD_BRCA1,HRD_BRCA2,HRD_BRCA1_or_BRCA2,CNV_DEL,CNV_AMP,CNV_class,CNV_idx,CNV_1q_DEL,CNV_3q_DEL,CNV_4q_DEL,CNV_1q_AMP,CNV_3q_AMP,CNV_4q_AMP,Purity_Immune,Purity_Cancer,Purity_Stroma,MSI_status,POLE_subtype,JAK1_MS_INDEL,JAK1_Mutation,Log2_variant_per_Mbp,Log2_SNP_per_Mbp,Log2_INDEL_per_Mbp,Log2_variant_total,Log2_SNP_total,Log2_INDEL_total,Genomics_subtype,Mutation_signature_C>A,Mutation_signature_C>G,Mutation_signature_C>T,Mutation_signature_T>C,Mutation_signature_T>A,Mutation_signature_T>G,WXS_normal_sample_type,WXS_normal_filename,WXS_normal_UUID,WXS_tumor_sample_type,WXS_tumor_filename,WXS_tumor_UUID,WGS_normal_sample_type,WGS_normal_UUID,WGS_tumor_sample_type,WGS_tumor_UUID,RNAseq_R1_sample_type,RNAseq_R1_filename,RNAseq_R1_UUID,RNAseq_R2_sample_type,RNAseq_R2_filename,RNAseq_R2_UUID,miRNAseq_sample_type,miRNAseq_UUID,Methylation_available,Methylation_quality +S001,C3L-00006,No,2,5,128N,C3L-00006-01,CPT0001460012,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,1,38.88,64,No,White,Not-Hispanic or Latino,Female,Anterior endometrium,NA,Unifocal,2.9,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,1,0.004595748,0.045125791,0.075643165,0.034381469,0.047247678,0.002878929,6.39E-10,0.79012722,0.010443511,0,0.017867521,0.036816257,0,0.088247615,0,0.035408717,0,0,0,0.020942068,0,0.024896194,0.047057934,0.072523873,0,0.00612096,0,0,0,0.00967535,0.37,2821.088429,4885.608881,7706.69731,0.767043727,0.769,0.253,-1.17,0.09,0.93,-0.7,0.04,1.67,-0.75,-0.01,-1.09,1.14,-0.67,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,1,0,1,0,0,0,1.43E-05,0.038877665,CNV_LOW,1.292639933,-0.016886191,-0.023339852,-0.023494917,0.005761569,0.009796749,0.014250962,0.060494906,0.730880164,0.208624931,MSI-H,No,WT,WT,5.090218957,5.014858245,1.450879273,10.06204614,9.984418459,5.832890014,MSI-H,8.300395257,1.482213439,72.52964427,14.42687747,1.383399209,1.877470356,Blood_normal,92b5e534-6cb0-43eb-8147-ce7d18526f5e_gdc_realn.bam,53dbb4d6-ce9d-4145-a33a-0c4d67e655df,Tumor,d9975c5f-288d-417d-bdb3-f490d9a36401_gdc_realn.bam,96c07fe5-d530-4c9b-92ce-49408feacb2c,Blood_normal,9f29ebe1-de5d-47a8-a54d-d1e8441409c6,Tumor,457f2c4d-ddf3-416e-bb50-b112eede02d5,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_TAGCTT_S17_L005_R1_001.fastq.gz,8a1efc47-1c29-417f-a425-cdbd09565dcb,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_TAGCTT_S17_L005_R2_001.fastq.gz,8c3fe9b7-7acd-4867-8d9c-a8e5d1516eda,Tumor,37bcba98-1094-459e-83ae-c23a602416fb,YES,PASS +S002,C3L-00008,No,4,16,130N,C3L-00008-01,CPT0001300009,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage IV,IA,0,39.76,58,No,White,Not-Hispanic or Latino,Female,Posterior endometrium,NA,Unifocal,3.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,NA,Cannot be determined,1,0.005666428,0.056677626,0.100222966,0.041562969,0.056081262,0.001627258,4.15E-09,0.738161488,0.004411131,0,0.00176099,0.002130758,0,0.026435753,0,0.014944149,0,0,0,0.004934448,0.00385161,0.016040522,0.00394293,0.027211297,0.010407182,0.007160341,0,0.015087431,0.011681456,0,0.15,2714.248104,3632.199987,6346.448091,0.752796065,-0.302,-0.0242,0.17,-0.32,-0.91,0.65,-0.54,2.41,-0.87,-0.07,-1.6,2.14,-0.53,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,9.31E-06,1.17E-05,CNV_LOW,0.118480401,0,-0.002698584,-0.01112554,0.000978501,0,0,0.082629765,0.715223373,0.202146861,MSI-H,No,WT,WT,3.941606385,3.451287679,2.440219926,8.861086906,8.330916878,7.169925001,MSI-H,14.64174455,2.803738318,64.48598131,15.26479751,0.934579439,1.869158879,Blood_normal,243bfb3c-d06b-4de5-a6c3-7fa7e2c5fb74_gdc_realn.bam,90257622-6bcc-43e7-a04f-f7397975d038,Tumor,f6924a26-a14f-45a3-b4bd-7a4592d34065_gdc_realn.bam,4501f315-bf8f-4611-821a-797ef180e25b,Blood_normal,846bf455-89b4-4840-b113-e529ffa13277,Tumor,1c0e0f84-4caf-4493-9b2f-8f5f9ef9231b,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_GGCTAC_S22_L007_R1_001.fastq.gz,555725e8-cba5-4676-9b0a-80100cbf9f47,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_GGCTAC_S22_L007_R2_001.fastq.gz,15235b12-b67a-4678-acc4-ed03d642bd5e,Tumor,492b50d8-ec35-46e7-a65d-06512aaee394,YES,PASS +S003,C3L-00032,No,1,2,131,C3L-00032-01,CPT0001420009,Tumor,No,United States,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,51.19,50,Yes,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior endometrium,Unifocal,4.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,4 or more,0.006418323,0.067375618,0.127155905,0.031354942,0.050682921,0.004971567,2.10E-10,0.712040724,0.039852399,0,0.050305497,0.043745478,0,0.217047308,0,0.001314347,0,0,0.018425297,0,0,0.122233997,0.020499422,0.049193367,0.021836951,0.039683645,0,0.033824616,0.027104312,0.094933366,0.78,3856.501277,6602.912323,10459.4136,0.570730195,-0.1,0.0767,-0.02,0.24,0.4,-0.25,1.25,0.16,-0.61,1.63,1.67,-0.9,0.43,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,5.93E-05,0.000243818,CNV_LOW,0.174427719,-0.001375124,-0.003122768,-0.005361581,0.003805798,0.003557554,0.002393507,0.260963289,0.365434419,0.373602292,MSS,No,WT,WT,1.142367912,0.970671335,0.319245674,5.321928095,5,3.169925001,CNV_low,16.12903226,3.225806452,70.96774194,3.225806452,3.225806452,3.225806452,Blood_normal,97e153c1-7be4-4d7b-9d30-9545b56e6ddb_gdc_realn.bam,75a4369c-5247-427d-aabc-3157d08f2d8f,Tumor,9de43644-2816-4fac-8e1e-b49b18b2707b_gdc_realn.bam,0ec56b8f-f64a-401e-be41-d873fa31776b,Blood_normal,a16b07d8-46c1-4fd9-8204-4f866aacfbec,Tumor,b93693c0-b88d-43d6-9b8b-97c8269982cc,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_GTCCGC_S18_L005_R1_001.fastq.gz,9ae968f3-691d-4db3-9977-1ab3e5af9085,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_GTCCGC_S18_L005_R2_001.fastq.gz,423b6b09-02aa-4f47-9241-f75c1dad1161,Tumor,1794ff56-db2d-4d1a-8758-cab7fe3d98c1,YES,PASS +S004,C3L-00084,Yes,3,11,129N,C3L-00084-01,CPT0000820012,Tumor,No,NA,NA,NA,Carcinosarcoma,YES,Normal,NA,NA,NA,NA,NA,NA,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-2.25,-1.63,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,NA,NA,NA,NA,-0.004758788,-0.011853715,-0.209865909,0.094452817,0.349513405,0.009282372,NA,NA,NA,MSS,No,WT,WT,1.835786443,1.732044006,0.319245674,6.392317423,6.247927513,3.169925001,NA,16,28,29.33333333,17.33333333,5.333333333,4,Blood_normal,b0c06553-0088-41fd-a0de-fecc9bb6574a_gdc_realn.bam,085f713e-b95c-4b59-ae60-22b70e8f499d,Tumor,e58981f9-0125-452a-9a6a-ad0c3116ebdd_gdc_realn.bam,d09a2cf2-6b59-43ca-aeea-494f099f879e,Blood_normal,edc0e018-cb28-4bf3-b1ff-39490924e401,Tumor,f6eac4de-7732-414b-bcd2-de1bab0a00a3,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_ATCACG_S5_L002_R1_001.fastq.gz,b0a7cdf2-2ad8-4442-91b0-548ea4975554,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_ATCACG_S5_L002_R2_001.fastq.gz,c83987a5-1c13-4af4-b46c-218fe5f60c34,NA,NA,YES,PASS +S005,C3L-00090,No,3,12,129C,C3L-00090-01,CPT0001140003,Tumor,No,United States,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,No pathologic evidence of distant metastasis,Stage I,IA,0,32.69,75,No,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior endometrium,Unifocal,3.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,4 or more,0.005577885,0.060593928,0.112090146,0.044365306,0.058249827,0.003754992,9.84E-10,0.715367914,0,0.019078676,0.007199854,0.047075193,0,0.06169803,0,0,0.022737675,0.002598418,0,0.014684549,0.002542568,0,0.018807855,0.122544366,0,0.0041831,0.065981557,0,9.00E-04,0,0.39,3012.556593,4462.910274,7475.466867,0.650749915,0.129,0.0696,-1.14,0.7,0.4,-1.85,-0.73,-0.39,-0.53,-1.06,-0.07,0.39,0.15,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.002260223,0.098113801,CNV_LOW,1.750745835,-0.043811447,-0.073670939,-0.050230318,0.00313913,0,0.000109284,0.076005374,0.571299524,0.352695102,MSS,No,WT,WT,1.349358266,1.258934249,0.207641466,5.672425342,5.523561956,2.584962501,CNV_low,17.77777778,8.888888889,62.22222222,8.888888889,2.222222222,0,Blood_normal,7959d3f4-80cb-45f5-99ea-248ac2059877_gdc_realn.bam,d74368b7-1924-4c44-8079-1858f7ebf85a,Tumor,cfc5140e-1c15-4b9f-83e0-5613e427870e_gdc_realn.bam,055e85d1-c36d-4fbd-b578-4fd23e81b9e5,Blood_normal,833145ed-db94-4cb2-8429-df062a71bd8a,Tumor,544edc00-ac31-47cf-9489-1a797eb22e53,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_GAGTGG_S10_L003_R1_001.fastq.gz,8ce5618d-9ff6-40f9-aeea-8d8e1633ae38,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_GAGTGG_S10_L003_R2_001.fastq.gz,06d3fd4a-a623-4146-8500-4f1f17235253,Tumor,a6524c2d-d7dd-4629-980e-b45dbdc92c49,YES,PASS +S006,C3L-00098,No,4,14,129N,C3L-00098-02,CPT0000980012,Tumor,No,United States,NA,under 50 %,Serous,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,NA,20.28,63,No,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior endometrium,Unifocal,6,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Normal,NA,Cannot be determined,2,0.003088213,0.014328871,0.063531838,0.031658353,0.063943075,0.007304327,8.69E-09,0.816145315,0.005773262,0,0.027627049,0.050190166,0,0.015101252,0.026119631,0.011140644,0,0.012162159,0,0.02318389,0,0.054263627,0.064099852,0.140338468,0,0,0,0,0,0,0.43,1717.74787,6545.943147,8263.691016,1,-2.18,-2.8,-0.98,-0.61,1.85,-2.14,0.89,-0.54,-2.51,-0.02,0.96,2.1,-1.98,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.330703347,0.24420711,CNV_HIGH,7.062483444,-0.01420399,-0.000856205,-0.381597562,0.131950499,0.268048184,0.064997832,0.26273407,0.623745319,0.113520611,MSS,No,WT,WT,1.634715536,1.530342916,0.282995148,6.108524457,5.95419631,3,CNV_high,9.836065574,13.1147541,62.29508197,3.278688525,8.196721311,3.278688525,Blood_normal,0f46b9b0-6bff-4156-b505-669d72cc9428_gdc_realn.bam,b58bdcce-b807-4958-814d-3576dee3ae0c,Tumor,40c0a0d3-bdfd-4fa1-9aaa-9e8c747cc53c_gdc_realn.bam,bdde9d09-6a54-46d9-985b-aaf95799f6f9,Blood_normal,385cdfe0-fbae-486f-b333-4a88d1209afb,Tumor,a64c4b72-0517-431f-8128-3a89ad7b387c,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_TTAGGC_S8_L002_R1_001.fastq.gz,31252ba9-e052-4b77-809a-f936379ae00c,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_TTAGGC_S8_L002_R2_001.fastq.gz,23be22ae-de50-4d74-a7c0-c890adbc662a,NA,NA,YES,PASS +S007,C3L-00136,No,4,16,129C,C3L-00136-03,CPT0000730011,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,55.67,50,No,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior endometrium,Unifocal,4.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,3,0.001629109,0.064998151,0.174134279,0.006508822,0.114858814,0.003170654,9.76E-10,0.634700169,0.001059623,0,0.012292451,0.089036423,0,0.218447078,0,0.014378883,0,0,0.084425262,0.014546171,0.041004139,0.027346769,0.012830509,0.145650337,0.00817583,0.012429489,0.21207275,0,0.006304285,0,0.9,3414.419984,5622.138932,9036.558917,0.385199529,-0.892,-0.983,1.34,-1.18,0.08,1.32,-0.24,1.04,0.78,-0.27,0.04,-0.76,0.56,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018445972,0.219721966,CNV_LOW,3.206485284,-0.00468552,-0.110063016,-0.119590154,0.588337381,0,0,0.189781135,0.554177035,0.25604183,MSS,No,WT,WT,1.182279033,1.101321187,0.168435383,5.392317423,5.247927513,2.321928095,CNV_low,16.21621622,13.51351351,51.35135135,8.108108108,8.108108108,2.702702703,Blood_normal,2a17380f-bcb1-4de3-8934-af1d4b914892_gdc_realn.bam,27465b6e-6b30-429d-9e0b-cac09c0a8f91,Tumor,0da07c96-e95e-45df-b12f-8c745696f271_gdc_realn.bam,5fc17a22-c109-4f25-8902-a7d9b7642915,Blood_normal,df7dc177-6120-49ae-9046-fffbeed04583,Tumor,9cb2d2f8-a700-4dbf-bc69-cb34274209b9,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_GTCCGC_S10_L003_R1_001.fastq.gz,df0e2942-c702-4135-81a0-fbec4439d753,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_GTCCGC_S10_L003_R2_001.fastq.gz,4e1ad404-4646-4828-91b9-e3c35a4ce505,NA,NA,YES,PASS +S008,C3L-00137,No,4,15,130N,C3L-00137-02,CPT0002010011,Tumor,No,Other_specify,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,1,25.68,60,No,White,Not-Hispanic or Latino,Female,"Other, specify",Both anterior and posterior,Unifocal,5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,2,0.004052783,0.09190801,0.07002453,0.042667198,0.056644142,0.001135568,8.13E-09,0.73356776,0.052107498,0,0.006136476,0.01781162,0,0.096159419,0,0.058437763,0,0,0,0.027957379,0.019246682,0,0.006238274,0.066621604,0,0.015480802,0,0.049418849,0.024383635,0,0.44,2309.012756,2928.488048,5237.500804,0.54271797,1.06,-0.745,0.16,0.41,-0.66,-0.28,-0.26,0.42,1.01,0.18,-2,0.58,-1.05,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.012181118,0,CNV_LOW,0.610544403,-0.000726575,-0.007950328,-0.005928216,0.009886273,0.013221618,0.019164116,2.27E-18,0.642431399,0.357568601,MSS,No,WT,WT,1.349358266,1.2211157,0.282995148,5.672425342,5.459431619,3,CNV_low,27.90697674,11.62790698,48.8372093,4.651162791,2.325581395,4.651162791,Blood_normal,552d7534-1fd1-490b-8751-9dff1bf55569_gdc_realn.bam,d5a11391-8b84-4be2-8a8e-62d1e646b786,Tumor,6b8b5928-258f-4f93-9e52-516db4562c2d_gdc_realn.bam,24d0c8fa-2bb4-465b-96f7-680566a44c2f,Blood_normal,3183b3b5-5fdf-4f74-928e-7493bd04c1eb,Tumor,be294530-6817-4729-b01c-e2845ddabf79,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_GTGAAA_S12_L003_R1_001.fastq.gz,8fcdd6a1-a7c7-41b5-8b44-e41f2237b236,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_GTGAAA_S12_L003_R2_001.fastq.gz,2bea607d-6eb2-4583-90d7-7823a3d8a572,NA,NA,YES,PASS +S009,C3L-00139,No,3,11,130N,C3L-00139-01,CPT0001850012,Tumor,No,United States,NA,50 % or more,Serous,YES,Normal,pT3a (FIGO IIIA),pNX,cM0,Staging Incomplete,Stage III,IIIA,1,21.57,83,No,White,Not-Hispanic or Latino,Female,"Other, specify",Both anterior and posterior,Unifocal,4,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Normal,NA,Cannot be determined,4 or more,0.003577571,0.067769323,0.065130682,0.032434667,0.067883558,0.001420519,4.04E-09,0.761783675,0,0,0.00615282,0.017771978,0,0.101975277,0,0.060458172,0.016090453,0.021748457,0,0.010194706,0.012905363,0.074245364,0.053001228,0.035774299,0,0.009007116,0.099926731,0,0.010748036,0,0.53,2515.79784,2838.299899,5354.097739,0.691597084,-0.997,-1.72,-0.59,-1.37,0.33,-0.19,-1.09,0.36,0.55,-1.18,-1.55,-1.16,-1.6,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0.331737971,0.274666466,CNV_HIGH,5.846872142,0,-0.000207719,-0.485607019,0.335791813,0.405527663,0,0.074969712,0.487728614,0.437301675,MSS,No,WT,WT,1.691133088,1.634715536,0.168435383,6.189824559,6.108524457,2.321928095,CNV_high,7.352941176,33.82352941,36.76470588,8.823529412,4.411764706,8.823529412,Blood_normal,f72de443-e927-4cbf-a81d-3c906af657db_gdc_realn.bam,3e395930-3001-49bf-95ca-7c96e0204b57,Tumor,41bf607b-596b-4c43-9cd5-f245cf6e15fe_gdc_realn.bam,fb433f9d-bb8a-41e3-a5a0-997b16abd0fe,Blood_normal,eaab07a2-6162-4605-a1ba-8ff3a0bebb60,Tumor,e8a2f8dd-5e48-4ebe-a47f-b933e330fd60,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_CAGATC_S1_L001_R1_001.fastq.gz,7785d5a1-a60d-41f9-86f3-e4ebc100704c,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_CAGATC_S1_L001_R2_001.fastq.gz,90ced367-0342-4739-93b2-4b1a4af800c4,Tumor,a02b2784-9e7f-41b1-8e53-707ae4371c45,YES,PASS +S010,C3L-00143,No,4,14,130C,C3L-00143-01,CPT0001910016,Tumor,No,United States,FIGO grade 1,Not identified,Endometrioid,YES,Normal,pT1 (FIGO I),pN0,cM0,Staging Incomplete,Stage I,IA,0,34.26,69,Yes,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior endometrium,Unifocal,5.2,Cannot be determined,NA,Cannot be determined,NA,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,NA,Cannot be determined,2,0.004179295,0.075393304,0.175829124,0.034775754,0.044993308,0.009247814,3.74E-07,0.655581026,0,0,0.034349671,0.305302969,0,0.257694874,0.002504556,0.10551234,0,0.030562897,0,0.017594418,0,0.079259476,0.091911576,0.352506586,0.061026835,0,0.021773803,0,0,0,1.36,4181.251111,8463.786011,12645.03712,0.614413457,-0.729,-1.79,-1.35,-1.4,0.97,-0.4,0.58,-0.88,-0.66,0.51,1.19,0.52,-1.39,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0.000232878,0.0418212,CNV_LOW,0.825469308,-0.000310868,-0.023866202,-0.025598317,0.554316666,0,0,0.314749855,0.516615598,0.168634547,MSI-H,No,WT,WT,4.362228844,3.961812528,2.581235568,9.306061689,8.882643049,7.339850003,MSI-H,21.86836518,1.6985138,42.46284501,22.71762208,6.157112527,5.095541401,Blood_normal,c043b586-b3c2-4a81-a4f3-ccc22a2ec00d_gdc_realn.bam,937a94b6-f52b-4bd0-a1e5-32b1d98e41ca,Tumor,791db96f-984d-4482-bd0c-5691bef0b600_gdc_realn.bam,b44bbc36-16b3-431f-878e-c2f9110f580e,Blood_normal,d4c330b5-d7f2-4f29-9002-e10479caa5ad,Tumor,699ff6b6-296d-4897-94c8-13d90dce5824,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_ACTTGA_S4_L001_R1_001.fastq.gz,6412838b-2f70-4b14-a6ee-3c7baca09fb0,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_ACTTGA_S4_L001_R2_001.fastq.gz,5d0a26e0-2739-4f38-9350-c685b44911d3,Tumor,872be4b7-1735-48a6-a3a2-7541ec65ea87,YES,PASS +S011,C3L-00145,No,3,9,131,C3L-00145-02,CPT0002630003,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,Staging Incomplete,Staging Incomplete,Stage I,IA,0,36.57,59,Yes,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior endometrium,Unifocal,4.7,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,3,0.004218625,0.159679699,0.096748688,0.042677677,0.110137007,0.003454382,4.99E-09,0.583083916,0.005885269,0,6.00E-04,0.016694075,0,0.215617674,0,0.072989693,0,0,0,0.060977392,0.045689566,0.063456552,0.023867009,0.122295409,0.033059137,0,0.042382678,0,0.010365772,0.006120479,0.72,4669.852221,5269.577209,9939.42943,0.270592352,0.0794,0.771,0.43,-0.3,-0.66,0.26,-0.02,-0.02,1.46,0.47,-0.61,-0.13,0.95,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.00015084,CNV_LOW,0.23259562,0,-0.005465167,-0.006784099,0.032914497,0,0,0.100674478,0.3855902,0.513735322,MSS,No,WT,WT,1.182279033,1.037474705,0.282995148,5.392317423,5.129283017,3,CNV_low,17.64705882,14.70588235,52.94117647,8.823529412,5.882352941,0,Blood_normal,2a8535dc-eb5a-4517-a7be-6d52d87a4233_gdc_realn.bam,a4663b3f-7399-4fb6-b11b-536983006cac,Tumor,24d1cc36-8239-4162-a2c2-6448607a4620_gdc_realn.bam,aabae279-c40a-4c09-92bc-e2f9d662eed7,Blood_normal,f0c2d7a9-4236-4c49-84bc-2c02169339dd,Tumor,fe66b253-513c-4b4d-a0fc-abd808170301,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_GAGTGG_S19_L005_R1_001.fastq.gz,1f5e3577-dbc5-46f7-8615-86887337a97e,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_GAGTGG_S19_L005_R2_001.fastq.gz,1c7f3fd1-e321-45b0-8e70-7ecad29c0558,Tumor,60e34478-d9d3-41ae-bf52-a328951196ad,YES,PASS +S012,C3L-00156,No,4,15,129N,C3L-00156-02,CPT0002080011,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,27.83,56,Yes,White,Not-Hispanic or Latino,Female,Anterior endometrium,NA,Unifocal,2.2,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,2,0.005791063,0.028713248,0.122822159,0.035670588,0.047452551,0.00692925,5.28E-09,0.752621136,0,0.015477154,0.050717552,4.00E-04,0,0.180804762,0,0.010317116,0.011980289,0,0.033211036,0.014532283,3.00E-04,0.128991522,0.006664382,0.151204409,0,0.022078706,0,0.018873801,0,0.024388609,0.67,2304.797045,5850.431589,8155.228634,0.665726073,0.75,-0.422,-1.11,0.72,1.02,-1.36,0,1.46,-1.41,0.22,0.77,1.05,0.47,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,1,0,0,1,1,0,1,0.0006768,0,CNV_LOW,0.103538746,0,0,-0.003059389,0.002757972,0.002000249,0,0.147902919,0.694163579,0.157933501,MSS,Yes,WT,Missense_Mutation,5.612520487,5.60519854,0.319245674,10.59712143,10.58965115,3.169925001,POLE,23.24675325,1.168831169,51.94805195,8.896103896,0.454545455,14.28571429,Blood_normal,ee8e3dc1-6ec7-44fe-9e3e-a7455e9920ac_gdc_realn.bam,a402cc2d-41ac-4d0a-ac99-3a014754fd49,Tumor,ed2b6a93-896d-4fc9-8e2b-00821b00fe58_gdc_realn.bam,799c73ad-e7de-45e6-9548-ac30072150e7,Blood_normal,75786b70-9e4a-42a8-892a-29812f7b0e20,Tumor,b2cf2d6b-1638-4d6b-8df3-8ebe30121041,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_GTGGCC_S16_L004_R1_001.fastq.gz,e1abab26-3582-4e7c-bbea-7cadbd0e36e5,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_GTGGCC_S16_L004_R2_001.fastq.gz,b92610bf-9bcd-4f26-948d-448f963586de,NA,NA,YES,PASS +S013,C3L-00157,Yes,4,13,130C,C3L-00157-02,CPT0002560003,Tumor,No,United States,NA,under 50 %,Clear cell,YES,Normal,pT3a (FIGO IIIA),pN2 (FIGO IIIC2),cM0,Staging Incomplete,Stage III,IIIC2,1,34.84,60,No,White,Hispanic or Latino,Female,Anterior endometrium,NA,Unifocal,4.2,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,3,0.004931836,0.008916274,0.097631079,0.02297888,0.089019671,0.005064803,1.52E-10,0.771457457,0,0,0.021917773,0.002189731,0,0.027412253,0,0.017302047,0.001802197,0,0,0.016747742,0.030421378,0.00561744,0.009263415,0.080331073,0,0.05295342,0,0.134807458,0,0.069234075,0.47,2212.345792,6285.433874,8497.779666,NA,-1.63,-2.86,0.38,1.35,0.94,-1.85,1.43,1.25,-1.62,1.67,-0.47,0.13,-1.13,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0.469507242,0.175301288,CNV_HIGH,4.417577316,-0.036731633,-0.007310833,-0.274529469,0.218618281,0.082265915,0.005930261,0.455792253,0.362982267,0.18122548,MSS,No,WT,WT,1.121990524,0.993284573,0.245810227,5.285402219,5.044394119,2.807354922,CNV_high,31.25,15.625,40.625,6.25,3.125,3.125,Blood_normal,8e4d5871-709e-49fa-aa5c-ab5e9060fca3_gdc_realn.bam,6b7c566b-4693-4ea8-979c-26fb83949551,Tumor,6fdfe226-a6b6-4836-a287-4b8b6e167e07_gdc_realn.bam,fc36eee8-07a4-4ff9-9a4c-5dab053b833b,Blood_normal,4679e568-2b87-4f05-a67c-9d52f0143e05,Tumor,a0a89248-1fe0-4b60-aaf3-49e1e971923d,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_CGTACG_S17_L005_R1_001.fastq.gz,ea887db4-6dcb-4e75-b57f-5a0211fb4ba6,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_CGTACG_S17_L005_R2_001.fastq.gz,9dd491c3-794c-4f2d-8010-512c90360b1b,NA,NA,YES,PASS +S014,C3L-00161,No,4,13,131,"C3L-00161-01,C3L-00161-02",CPT0070380004,Tumor,No,United States,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN0,Staging Incomplete,No pathologic evidence of distant metastasis,Stage I,IB,1,68.39,46,No, White,Hispanic or Latino,Female,"Other, specify",Anterior and Posterior Endometrium,Unifocal,7,Cannot be determined,NA,Cannot be determined,NA,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,NA,Absent,2,0.005614163,0.097078048,0.113625405,0.034682381,0.105438711,0.002562586,3.03E-09,0.640998702,0,0,0.029774138,0.23977877,0,0.072129432,0,0.077566594,0.026782261,0,0.067142743,0,0.021205627,0.062962959,0.056281696,0.117348345,0.012365358,0,0.106293289,0,0,0.020368787,0.91,2869.70182,5255.761765,8125.463586,0.51938048,-0.995,-2.4,2.12,0.42,-0.64,1.83,0.21,-0.04,0.12,-0.27,-0.02,0.35,1.2,0,1,1,1,0,1,0,0,0,0,0,0,1,0,0,0,0,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.017465096,CNV_LOW,0.175460897,-0.00100262,-0.005212673,-0.005595477,0,0,2.79E-06,0.142389668,0.643834137,0.213776195,MSI-H,No,MS_indel,Frame_Shift_Del,4.875737466,4.335929558,3.34540868,9.840777924,9.278449458,8.214319121,MSI-H,15.64516129,1.612903226,61.4516129,17.25806452,2.580645161,1.451612903,Blood_normal,86fb70f6-d13a-4fdf-80eb-a744902cbec2_gdc_realn.bam,47d0c160-601e-445d-b19e-77a5d20d623f,Tumor,a9ccc7bf-8b4f-43bb-90ce-d943ea5bac6e_gdc_realn.bam,b6c8e44f-c2d4-4353-b4a2-8859e573da0b,Blood_normal,e8353960-b692-41e4-b7c3-007b1d54f4a2,Tumor,58d48892-e06c-4389-8a66-efe483c39f35,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_CGATGT_S6_L008_R1_001.fastq.gz,9e12b685-c46a-431b-bb9e-a90c6f7892ee,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_CGATGT_S6_L008_R2_001.fastq.gz,787253e0-0877-4bfa-98f5-9a258f8e1b57,NA,NA,YES,PASS +S015,C3L-00356,Yes,3,11,129C,C3L-00356-01,CPT0002130003,Tumor,No,United States,NA,under 50 %,Carcinosarcoma,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,1,25.37,73,No,White,Not-Hispanic or Latino,Female,"Other, specify",Both anterior and posterior endometrium,Unifocal,3.9,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,2,0.005414938,0.025758874,0.070554976,0.027960938,0.044537714,0.001488506,5.19E-10,0.824284054,0.024455326,0,0.06845052,0.02094494,0,0.027481813,0,0.0549426,0,0,0,0.054428947,0,0.128290373,0.022855717,0.094933198,0,0.036388646,0.007330618,0,0.008005031,0.001492271,0.55,1945.541934,3256.99141,5202.533343,NA,-2.41,-1.9,0.38,-0.1,0.53,0.85,-0.74,-0.21,1.07,-0.95,0.37,-0.56,-0.35,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.403159273,0.272816019,CNV_HIGH,NA,-0.076781268,-0.065265686,-0.290586275,0.003074446,0.683586023,0.004786549,0.133055973,0.500491115,0.366452912,MSS,No,WT,WT,1.2211157,1.182279033,0.086674411,5.459431619,5.392317423,1.584962501,CNV_high,24.3902439,7.317073171,46.34146341,4.87804878,4.87804878,12.19512195,Blood_normal,0d1a19ed-b1f4-4d0f-9eff-5922afcb6cbe_gdc_realn.bam,b94ff0a4-127b-4fac-9a68-2ec50ce6c202,Tumor,e6e1c2a6-27c3-4d55-87ed-6cd0ab0fd6b6_gdc_realn.bam,cece60fc-811e-4d03-9f7e-731f0b80212f,Blood_normal,8b2d66ef-8fc7-47b4-9717-2dc51259c0a6,Tumor,b841bd14-fc26-40a4-b89b-f7fc50cdc513,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_CGATGT_S11_L004_R1_001.fastq.gz,4b2a33c2-3d9a-405c-9d10-049bed615f1d,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_CGATGT_S11_L004_R2_001.fastq.gz,2e91202d-2403-4619-8111-5f26fdf879b1,NA,NA,YES,PASS +S016,C3L-00358,No,1,3,130N,C3L-00358-01,CPT0002210011,Tumor,No,United States,NA,50 % or more,Serous,YES,Normal,pT1b (FIGO IB),pNX,cM0,Staging Incomplete,Stage I,IB,1,26.22,90,No,White,Not-Hispanic or Latino,Female,"Other, specify",Both anterior and posterior endometrium,Unifocal,4.5,Positive,75,Positive,5,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Overexpression,"CD10 is negative. CD56 and Synaptophysin stains highlight the neuroendocrine component, while chromogranin stain is largely negative.",Cannot be determined,Unknown,0.005182084,0.022440994,0.105618133,0.018651113,0.04257597,0.00569926,1.49E-10,0.799832446,2.00E-04,0,0.087616998,0.048920734,0,0.136319654,0,0.016860233,0,0,0,0.081825121,0,0.102629415,0.092353708,0.213796665,0,0,0,0.07237302,3.00E-04,0.006842302,0.86,2379.6735,6074.369909,8454.043409,0.900919036,-0.67,-2,-1.32,-1.4,0.83,-0.07,0.79,0.25,-0.98,0.69,-0.07,-0.33,-2.19,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.372287041,0.269313888,CNV_HIGH,6.264013781,-9.85E-05,-0.021353659,-0.278804664,0.26160588,0.326433728,0.007941129,0.223339079,0.53935279,0.237308131,MSS,No,WT,WT,2.066555769,1.93256673,0.455772534,6.700439718,6.523561956,3.700439718,CNV_high,10.98901099,36.26373626,36.26373626,7.692307692,2.197802198,6.593406593,Blood_normal,8927cd25-7348-4319-8a9b-248fc0bc8e56_gdc_realn.bam,70b053c6-05af-43b7-8393-bef10a4390a9,Tumor,ea49ecce-a8c3-410f-987b-07364fee8b18_gdc_realn.bam,15b5f6c6-6f94-43c2-951c-72df48f24ee2,Blood_normal,bb62f2d2-b146-490a-bc13-b209c265d28d,Tumor,573df828-ddd8-43e5-9dc2-513911ee977f,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_GTTTCG_S2_L001_R1_001.fastq.gz,9cb3b6ce-7b2a-4225-b0e7-d32d47171740,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_GTTTCG_S2_L001_R2_001.fastq.gz,e9a087df-10b2-498e-90d3-cd60747088b8,NA,NA,YES,PASS +S017,C3L-00361,No,1,2,127C,C3L-00361-01,CPT0002430011,Tumor,No,United States,FIGO grade 1,Not identified,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,42.98,64,Yes,White,Not-Hispanic or Latino,Female,Anterior endometrium,NA,Unifocal,2.7,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,NA,Cannot be determined,None,0.005114234,0.025807817,0.092134705,0.037330484,0.062030244,0.000940909,6.77E-10,0.776641607,0.005639499,0,0.022842137,0.029908963,0,0.095277213,0,0.006606719,0.015668239,0,1.00E-04,0.002681846,0.004718605,0.007085054,0.01282946,0.058647987,1.00E-04,0.009461798,0.027745052,0,7.00E-04,0,0.3,613.0876971,2936.879453,3549.96715,0.955786378,0.443,0.75,-1.16,-1.66,0.1,-0.19,-1.97,0.39,-2.33,-1.78,-2.3,1.56,-1.69,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1.11E-05,0.041329089,CNV_LOW,1.300911329,-0.000490928,-0.038363057,-0.043604925,0.810292168,0,0,0.046460963,0.848208592,0.105330444,MSI-H,No,WT,WT,4.415525945,4.056121768,2.512450001,9.361943774,8.982993575,7.257387843,MSI-H,19.00990099,2.772277228,48.31683168,18.01980198,8.316831683,3.564356436,Blood_normal,7df399c7-9281-4eb1-8e1b-9d88c80e5881_gdc_realn.bam,9c34aa06-3655-49af-86ea-83132b1eb953,Tumor,8c244af7-4d0a-447d-8da2-af9d147718aa_gdc_realn.bam,15474b0b-f26e-4516-80ec-aca7986d8282,Blood_normal,294e6bb9-3965-42e0-8a2b-d954c16990f0,Tumor,47f3fed4-4116-4843-9843-0ab433dad9a4,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_ACTGAT_S12_L004_R1_001.fastq.gz,d1c64f6f-aa85-463a-8773-69513cad82a7,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_ACTGAT_S12_L004_R2_001.fastq.gz,c0cbd504-5d93-4f9d-bb5a-1cbe602f2a3d,Tumor,a30ec717-112c-4f16-86c9-e31d765d7033,YES,PASS +S018,C3L-00362,No,2,5,130N,C3L-00362-02,CPT0002500011,Tumor,No,United States,FIGO grade 1,Not identified,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,55.86,38,Yes,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior endometrium,Unifocal,13.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Normal,P16 and BCL2 positive,Absent,None,0.00332298,0.200220933,0.095114204,0.040712363,0.07238533,0.00133655,2.86E-09,0.586907637,0.028168355,0,0.008908075,0.05901444,0,0.158299126,0,0.027016898,0.028332406,0,0,0.018869097,0.046614126,0.052890205,0,0.06641301,0.030543531,0.032192268,0.034316037,0,0,0.018422424,0.61,2953.951139,3924.864459,6878.815598,0.466250633,-0.153,0.604,0.68,-1.31,-0.53,1.52,-0.82,0.64,0.67,-0.6,-1.08,-0.65,2.14,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0.348704409,0.128758751,CNV_HIGH,4.16601537,-0.000537474,-0.210417756,-0.165150754,0.224806047,0.010537265,0.015115205,0.130018403,0.514841368,0.355140229,MSS,No,WT,WT,0.801600757,0.775745316,0.043988012,4.64385619,4.584962501,1,CNV_high,30.43478261,13.04347826,39.13043478,4.347826087,8.695652174,4.347826087,Blood_normal,fabf7d4a-34b3-4c27-8921-035cace2795b_gdc_realn.bam,20d5f472-7ada-4026-ad90-c4aee6490d47,Tumor,cc81280d-f906-4e45-a988-000aeb16fcdf_gdc_realn.bam,e297322a-2b1a-4610-a5d7-bb31fffd07bc,Blood_normal,40d09165-a271-453d-9bd0-1f6056b7b83d,Tumor,3af7e6a3-594d-4830-a5ea-cef88e23f906,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_ATTCCT_S6_L004_R1_001.fastq.gz,638dd879-a5ee-437c-9f30-c97dcfa19a09,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_ATTCCT_S6_L004_R2_001.fastq.gz,a02f460b-1cbd-4c92-a5ef-9928088c8c1e,Tumor,817eff3d-6e39-45e1-bcee-fca423af1aef,YES,PASS +S019,C3L-00413,No,4,13,130N,C3L-00413-01,CPT0009980003,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT2 (FIGO II),pN0,cM0,Staging Incomplete,Stage II,II,0,42.19,60,No,White,Not-Hispanic or Latino,Female,"Other, specify",Both anterior and posterior,Unifocal,3.2,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,3,0.002976646,0.032530637,0.072912978,0.076101921,0.074618826,0.00116644,1.17E-09,0.739692551,0.012463677,0,0.001624051,0,0,0.104674412,0,0.060904492,0,0,0.029287744,0,0.033466742,0.048188695,0,0.022231967,0,0.042889981,0,0.018753335,0.018264584,0.01725032,0.41,1184.03053,3696.358111,4880.388642,0.501202113,-1.63,-2.57,1.78,1.11,-1.4,1.54,-0.23,1.19,0.57,0,-1.02,2.24,1.64,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.001083995,0.167850707,CNV_LOW,2.92410267,-0.091810653,-0.097520363,-0.103711441,3.80E-05,0.000125954,7.34E-05,0.158828136,0.632079059,0.209092805,MSS,No,WT,WT,1.331721187,1.258934249,0.168435383,5.64385619,5.523561956,2.321928095,CNV_low,15.55555556,8.888888889,57.77777778,8.888888889,4.444444444,4.444444444,Blood_normal,92bebf14-5fd0-453e-99a3-c7041b9cde22_gdc_realn.bam,6058412c-d366-44dd-a0fc-4aad9f6166dc,Tumor,ef798c59-f595-45b8-960e-6b36c8169fb9_gdc_realn.bam,f9bf7283-eb23-477d-bc36-b928c96ff1f2,Blood_normal,22c5648f-e238-4e98-b2d5-32d41ab94314,Tumor,7cd7dd5b-4c04-4f55-88c5-73a813a1b7a8,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_GTGAAA_S1_L006_R1_001.fastq.gz,e46aae2a-0162-443c-9f2d-7f95cd2f132e,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_GTGAAA_S1_L006_R2_001.fastq.gz,05b8da1e-d495-4023-9aca-b71417350ee1,Tumor,77466cca-387b-4e58-861c-bb2e74085989,YES,PASS +S020,C3L-00449,No,2,5,131,C3L-00449-01,CPT0007100003,Tumor,No,United States,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,27.82,59,No,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior endometrium,Unifocal,7,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,NA,Cannot be determined,None,0.005195016,0.103207263,0.13687414,0.035558676,0.132518871,0.003291385,3.95E-09,0.583354645,0.011222617,0,0.051383493,0.061136375,0,0.284732939,0,0.052863572,0,0,0,0.009243439,0,0.027789143,0.052425878,0.154422067,0.011092339,0.028793179,0.047224779,0,0,0.137670181,0.93,5176.758433,6698.972556,11875.73099,0.334225635,-0.23,-0.407,1.57,0.42,1.93,0.75,0.77,0.27,1.1,1.31,1.03,0.09,1.65,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018199062,0.044998681,CNV_LOW,0.448567224,-0.010880178,-0.011242408,-0.013211994,8.84E-05,0,0,0.237359854,0.330364549,0.432275597,MSS,No,WT,WT,1.560942049,1.434447489,0.319245674,6,5.807354922,3.169925001,CNV_low,12.72727273,3.636363636,61.81818182,7.272727273,5.454545455,9.090909091,Blood_normal,5a75740b-ad5b-4f29-8b9e-1d011f50aac7_gdc_realn.bam,e8723283-d74f-456f-90e8-7a54b0d8abe2,Tumor,73d8e268-db73-4fa5-b943-4e99a762e81a_gdc_realn.bam,497a5093-f4f0-4fbd-b869-77bec7018f5b,Blood_normal,688ef886-6324-46d5-89ee-11be2c3c3b8b,Tumor,79b0a390-f6b2-4eb1-a905-90f69c0104e5,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_CGATGT_S16_L004_R1_001.fastq.gz,f77c5bff-f9df-4a57-a2e9-391fcd5a6ba2,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_CGATGT_S16_L004_R2_001.fastq.gz,1faa1af4-b72b-4267-a86a-893fa2f67d7f,Tumor,ce10e000-0fb6-4697-9ad3-16ef7f03d668,YES,PASS +S021,C3L-00563,No,3,11,128N,C3L-00563-03,CPT0063250003,Tumor,No,Other_specify,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,No pathologic evidence of distant metastasis,Stage I,IA,0,34.72,62,Yes,Asian,Not-Hispanic or Latino,Female,"Other, specify",Both anterior and posterior,Unifocal,3,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,1,0.005543654,0.017993074,0.086076324,0.050296678,0.087109023,0.001089022,1.95E-10,0.751892225,0,0.014642819,0.028840788,0.087713967,0,0.107587815,0.009782414,0,0,0,0,0.016213555,0.018172299,0.043837507,0.012564144,8.00E-04,0.001049951,0.004345187,0.016645745,0,0.007794239,0,0.37,864.2241924,3523.379962,4387.604155,0.61702856,0.616,1.47,-0.57,-0.12,-1.02,-0.1,-1.4,-0.28,-0.41,-1.52,-1.39,0.35,0.67,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.065467984,CNV_LOW,1.827783368,-0.000633572,-0.052457471,-0.055272951,0.713144091,0,0,0.085761394,0.713908354,0.200330252,MSS,No,WT,WT,1.401011577,1.331721187,0.168435383,5.754887502,5.64385619,2.321928095,CNV_low,6.12244898,6.12244898,63.26530612,14.28571429,6.12244898,4.081632653,Blood_normal,f38738f1-ed43-4824-9c84-b23a66d122b2_gdc_realn.bam,f80735d2-6a7e-4d58-965d-5b3b48520bd0,Tumor,e1743cdd-69f2-4643-810d-4f1c677560ac_gdc_realn.bam,1b3536a2-9329-4dd7-a180-fdeb3e6c96e8,Blood_normal,611aab51-5e8b-42a5-a07c-0f263c5b99cb,Tumor,8135d8d2-1d84-43d2-ac41-4eec5cebb607,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_TGACCA_S7_L002_R1_001.fastq.gz,8b076b0a-e1a0-4215-ab01-2aa7e0a0d947,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_TGACCA_S7_L002_R2_001.fastq.gz,9c892a88-3d18-4757-8c0c-ae75966102c7,Tumor,45eec88a-c933-459c-8dce-9fbbfedda949,YES,PASS +S022,C3L-00586,No,2,6,129C,C3L-00586-03,CPT0023630003,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT2 (FIGO II),pN2 (FIGO IIIC2),cM0,Staging Incomplete,Stage III,IIIC2,1,21.45,50,No,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and posterior endometrium,Unifocal,6,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,2,0.006596366,0.064384568,0.126116005,0.0421249,0.104962403,0.005944262,5.66E-12,0.649871496,0.023552518,0,0.047689147,0.018563104,0,0.176219029,0.007532985,0.083529995,0,0.052661005,0,0.013514406,0,0.036327449,0.05725825,0.110485885,0.004780403,0,0,0,0.001638531,0.006247294,0.64,3748.640733,6767.884691,10516.52542,0.624274153,-0.715,-0.336,1.82,-0.19,1.49,1.31,0.56,0.57,-0.8,0.29,0.34,0.33,0.43,1,0,0,1,1,1,0,0,1,0,0,1,0,0,1,0,0,1,1,1,1,0,0,1,1,1,0,1,0,0,1,0,1,0,1,1,0.020352993,0,CNV_LOW,0.117984612,-2.55E-05,-0.000868323,-0.005118486,0.01153052,0,0,0.205001063,0.582138542,0.212860395,MSS,Yes,WT,WT,8.737485435,8.7318234,1.417826394,13.74766852,13.74199358,5.781359714,POLE,42.00729927,0.270072993,38.64963504,8.686131387,1.102189781,9.284671533,Blood_normal,dde47804-86f0-4b49-b448-483e4353bc22_gdc_realn.bam,38df11e7-4962-4828-a4bb-556f360d21a3,Tumor,c14109ad-a867-4f58-9e70-a7575597416a_gdc_realn.bam,8cf50c93-9dec-4515-82a7-1959f8e7f312,Blood_normal,cf887209-91e9-4a98-af3f-1559013596d4,Tumor,e9d15bfb-5cca-4f62-9cd6-247f8fe3e58e,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_ACAGTG_S23_L008_R1_001.fastq.gz,20fcc809-dcdf-46c5-b40d-c1aa39c6791c,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_ACAGTG_S23_L008_R2_001.fastq.gz,e731e945-44ae-4179-9672-a2a6a1fb2d94,Tumor,c250313a-9102-410f-9083-713007b3910f,YES,PASS +S023,C3L-00601,No,2,6,127C,C3L-00601-02,CPT0007600003,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,25.03,57,No,White,Not-Hispanic or Latino,Female,"Other, specify",Both anterior and posterior,Unifocal,3.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,3,0.005166918,0.022602285,0.116480361,0.038409552,0.063408919,0.002075369,1.70E-10,0.751856594,0.031297567,0,0.053445267,0.072290433,0,0.079296814,0.035281171,0.083814428,0,0.009010017,0,0.02793142,0,0.026942536,0.029796878,0.075305468,0.004461257,0,0,0.001126745,0,0,0.53,1706.11003,4850.828051,6556.938081,0.724145823,0.372,-1.03,0.31,1.38,-1.63,0.82,-0.49,0.81,-0.17,-1.01,-0.78,-0.07,-0.44,1,0,0,0,0,1,0,0,1,0,0,1,0,0,0,0,0,0,1,0,1,0,0,1,0,0,0,0,0,0,1,1,1,1,0,1,0.018033471,0.052014371,CNV_LOW,0.36400443,-0.028557583,-0.003489469,-0.010103645,0,0.000349225,0.000650063,0.141321035,0.651375137,0.207303827,MSS,Yes,WT,Nonsense_Mutation,7.006927428,6.998568599,0.801600757,12.00947875,12.00105627,4.64385619,POLE,44.28989751,0.268423621,39.97071742,7.637872133,1.171303075,6.661786237,Blood_normal,50c4a6f8-9efd-4898-a962-a7d89078b9b5_gdc_realn.bam,b7d63e3b-56bd-446b-a6ef-c6197ef84a94,Tumor,84ccff59-af29-4cbf-8068-185a2e2b4c1f_gdc_realn.bam,52aa202f-2d6e-4b6d-bbae-49bdda1d0f3c,Blood_normal,db638288-3dbf-436b-8444-56185109f1eb,Tumor,50107236-d227-4b6c-bd75-b9e860965ea2,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_ACAGTG_S3_L001_R1_001.fastq.gz,01b9fd20-8317-4067-84cf-e73dd8f92572,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_ACAGTG_S3_L001_R2_001.fastq.gz,5efbd40c-4225-4a7f-9920-71357ccf41f0,Tumor,bc1f150a-bba5-4b3e-a911-3c0fb2bd2c3f,YES,PASS +S024,C3L-00605,No,3,12,127N,C3L-00605-01,CPT0063890003,Tumor,No,United States,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,No pathologic evidence of distant metastasis,Stage I,IA,0,38.54,73,No,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior,Unifocal,2.7,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,Unknown,0.004118258,0.064685078,0.091412586,0.035879255,0.073710586,0.004558948,3.50E-09,0.725635286,0.009964698,0,0.055385291,0.067875939,0,0.049639616,0,0.069693176,0,0,0,0.054924606,0.057276039,0.006640164,0.013094056,0.147629049,0.010183766,0.036799065,0.018269735,0,0,0.0226248,0.62,3006.948997,4977.8832,7984.832197,0.519451692,-0.103,0.108,0.6,0.47,-0.51,0.54,-0.29,0.33,0.2,0.24,-0.94,0.41,1.95,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,2.22E-05,0.045314014,CNV_LOW,0.743913927,-0.017919344,-0.019029565,-0.021835922,0,0,0.000973227,0.086578499,0.607380774,0.306040727,MSS,No,WT,WT,1.691133088,1.560942049,0.354607617,6.189824559,6,3.321928095,CNV_low,14.28571429,9.523809524,61.9047619,9.523809524,0,4.761904762,Blood_normal,9c7363c2-750a-408e-aa11-1bfaae41e7d0_gdc_realn.bam,54a0c2d4-cbb6-41f9-bfaa-e8c58c7f5362,Tumor,d9a888d9-211a-4a13-bbed-23dba208a9d2_gdc_realn.bam,d3e79d6a-2baf-4059-9ecb-ec1073619f26,Blood_normal,8f0c137b-dc5d-43c6-81e8-d728d8a1c5a8,Tumor,e8fc5d11-248f-4095-b9bd-e4f2c732e6fb,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_AGTTCC_S22_L006_R1_001.fastq.gz,2ef7f6a7-6298-4cd2-a38b-9b810905ab57,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_AGTTCC_S22_L006_R2_001.fastq.gz,7056adfe-ff91-4228-91b4-9954ba0148dd,Tumor,e06eb928-39e8-491a-bf5f-395f69acf724,YES,PASS +S025,C3L-00767,No,3,12,131,C3L-00767-01,CPT0026430003,Tumor,No,Other_specify,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,65.71,56,No,White,Not-Hispanic or Latino,Female,Anterior endometrium,NA,Multifocal,2.3,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Normal,NA,Absent,4 or more,0.005662834,0.078699134,0.10828337,0.046021406,0.077628328,0.002766177,3.70E-09,0.680938746,0.001468636,0,0.003981782,0.019412424,0,0.082865548,0,0,0.006352148,0,0,0.042554994,0.009198579,0.017816682,0.003920914,0.110666462,0.002742905,0.009009601,0.092315548,0,0,0.007693776,0.41,2565.123134,3893.125442,6458.248576,0.445231747,-0.066,0.667,0.08,0.17,-1.75,-0.02,-1.2,-0.69,-0.46,-0.99,-0.88,0.33,-0.57,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.017682543,0.045375442,CNV_LOW,0.968385832,-0.02658492,-0.021106253,-0.019964098,0.002878658,0,0,0.030069605,0.669628949,0.300301446,MSS,No,WT,WT,1.499080695,1.401011577,0.245810227,5.906890596,5.754887502,2.807354922,CNV_low,20.75471698,7.547169811,52.83018868,11.32075472,5.660377358,1.886792453,Blood_normal,7993ec03-5c3f-4f2a-920d-33dbf262d40a_gdc_realn.bam,07e62483-1397-4efc-be62-9009f7568709,Tumor,bf2c19ca-4c02-444c-8137-65a17c479448_gdc_realn.bam,30f59c0f-6d2c-4513-beb7-0d9792fa3edb,Blood_normal,d859af69-ac8f-4a4a-a376-9a6af50c07f3,Tumor,87dc9106-3c23-4cd3-8a85-6992800a5673,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_CAGATC_S15_L004_R1_001.fastq.gz,398b396a-17ba-4210-a645-a0f049b6e01e,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_CAGATC_S15_L004_R2_001.fastq.gz,b906f8b8-457b-4eed-bcc9-e9fb458b8bfa,Tumor,88c71434-68d4-4496-b299-65ffe96d3c3f,YES,PASS +S026,C3L-00769,No,2,5,129N,C3L-00769-01,CPT0026530003,Tumor,No,Other_specify,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN0,cM0,Staging Incomplete,Stage I,IB,0,46.64,56,No,White,Not reported,Female,Anterior endometrium,NA,Multifocal,4.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,2,0.005557191,0.115973086,0.094754968,0.06307061,0.100176584,0.004079595,8.81E-10,0.616387965,0.017468027,0,0.011671998,0.060441238,0,0.176943387,0.007105428,0.012846689,0,0,0.020821045,0.051867091,0.015500241,0.015333559,0.023880414,0.139210676,0.002732616,0.001379743,0.072599294,0,0,0.010198554,0.64,4634.296239,4977.305287,9611.601525,0.271365818,0.241,0.951,-0.06,-0.66,-0.14,-0.19,-0.4,-1.69,0.94,-0.46,0.01,-0.38,1.12,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.019047801,CNV_LOW,0.037652558,0,-0.001245513,-0.004003871,0.001724522,0,0,0.055775942,0.28695343,0.657270628,MSS,No,WT,WT,1.201828046,1.080351414,0.245810227,5.426264755,5.209453366,2.807354922,CNV_low,13.88888889,13.88888889,58.33333333,8.333333333,5.555555556,0,Blood_normal,4f90dd58-4dc8-4338-95ae-ce993e9370e4_gdc_realn.bam,72f9d84b-db67-4e8a-89ce-b5e9ce97c214,Tumor,a0c6d074-5bd3-4293-a7f7-fc4366b926a4_gdc_realn.bam,fe1bab24-7e25-4cf8-ac7e-09ee67eedaa6,Blood_normal,3a884473-fe8a-45e8-ae2d-eaaeaae500da,Tumor,d8f8126d-326b-43ee-b830-62377996a4d3,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_ACTTGA_S14_L004_R1_001.fastq.gz,b279cd43-c02c-42f0-8c35-aaf3a15d1d3d,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_ACTTGA_S14_L004_R2_001.fastq.gz,89545c45-58a9-44f7-a03e-f0c0cf2a901f,Tumor,d51c9ba6-3ae1-4aff-a626-f625b2468af0,YES,PASS +S027,C3L-00770,No,3,9,127N,C3L-00770-01,CPT0026650003,Tumor,No,Other_specify,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,45.83,73,Yes,White,Not-Hispanic or Latino,Female,Anterior endometrium,NA,Multifocal,2.7,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,4 or more,0.005909312,0.036781095,0.10856077,0.052156669,0.067570639,0.003399076,1.44E-08,0.725622424,8.00E-04,0.002332159,0.006063698,0.057224851,0,0.124472718,0,0,0.04120487,0,0.019629883,0,0,0.062493983,0.011079146,0.053857024,0.018233193,0.008867171,0,0.035334153,0,0.048423841,0.49,2347.226471,5163.497494,7510.723965,0.684164791,0.135,0.243,-0.83,1.84,0.3,-0.87,0.31,0.11,-1.18,0.96,-0.42,1.33,-0.85,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,1,0,1,0,0,0,0,0,0,1,0,0,0,0.002211541,2.00E-07,CNV_LOW,0.10422179,0,0,0,0.000816684,0.00090885,0.000754789,0.202506396,0.610413148,0.187080456,MSS,Yes,WT,Missense_Mutation,5.025868086,5.016239079,0.282995148,9.995767151,9.985841937,3,POLE,33.36623889,0.493583416,42.34945706,6.614017769,0.592300099,16.58440276,Blood_normal,330d5168-11d4-4bd3-924c-00a48a2e77f6_gdc_realn.bam,44017bf5-1244-4370-a7df-d8d40c18841c,Tumor,9c061602-847f-499d-bc0d-1761c1964373_gdc_realn.bam,8db62179-1b8d-4ed0-b1eb-e7145b9db850,Blood_normal,ee622934-1e17-44f8-8d8d-41011cc7e50e,Tumor,f9d8547d-be92-461a-b9ce-30c2deb01239,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_GATCAG_S11_L003_R1_001.fastq.gz,866a0af4-d611-4690-89f7-a6bd28807494,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_GATCAG_S11_L003_R2_001.fastq.gz,f5bbe1ad-856b-4c71-bd70-e538c2b1898e,Tumor,a2a7a853-0dc7-4476-b3cf-498a1a0e7a3b,YES,PASS +S028,C3L-00771,No,3,11,127N,C3L-00771-01,CPT0026770003,Tumor,No,Other_specify,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT3a (FIGO IIIA),pN0,cM0,Staging Incomplete,Stage III,IIIA,1,22.86,86,No,White,Not-Hispanic or Latino,Female,Posterior endometrium,NA,Multifocal,6,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,Unknown,0.005200559,0.065950716,0.10865991,0.049383477,0.267129768,0.003655548,1.99E-09,0.500020021,0.022073223,0,0.031251803,0.051264159,0,0.139556902,0,0.015331903,0,0,0,0.021782958,0.027223716,0.04413059,0.006318375,0.105220232,0,0.023599304,0.130442357,0.019248281,0,0.002556199,0.64,6048.630658,5780.984035,11829.61469,0.131521622,0.205,-0.912,0.71,-0.21,-0.02,0.11,0.17,-1.3,2.19,0.29,0.29,-0.72,0.41,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.044799188,CNV_LOW,0.629254484,-0.017869153,-0.015028621,-0.012660904,0.000277034,3.93E-05,0,0.069933635,0.298756785,0.63130958,MSS,No,WT,WT,1.860596943,1.771826721,0.282995148,6.426264755,6.303780748,3,CNV_low,10.25641026,3.846153846,73.07692308,5.128205128,6.41025641,1.282051282,Blood_normal,2bbab210-8789-4844-9de7-509231db0e6c_gdc_realn.bam,e757f535-dfb5-452d-9796-87c50fa8a73b,Tumor,506829d5-3821-445a-b4c7-083fb483e8dc_gdc_realn.bam,319b9314-8f00-49f7-899e-727a6b5fafd4,Blood_normal,4b0f79f5-6bce-4af8-a6eb-a52a896cfe48,Tumor,0459b7a4-b983-423b-bdf6-f7d93f8f5cba,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_TAGCTT_S10_L003_R1_001.fastq.gz,a6fab0ab-ce4b-44cb-bf38-b9db4caa2e70,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_TAGCTT_S10_L003_R2_001.fastq.gz,8a6ab525-f78c-4814-89f3-4b487a4a847c,Tumor,6f3c3bb1-4d83-4cb1-bf1e-27d3489a55e6,YES,PASS +S029,C3L-00780,No,2,7,129N,"C3L-00780-03,C3L-00780-05",CPT0070330004,Tumor,No,Other_specify,FIGO grade 2,Not identified,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,No pathologic evidence of distant metastasis,Stage I,IA,0,46.41,69,Yes,White,Hispanic or Latino,Female,"Other, specify",Posterior and Anterior Endometrium,Unifocal,1.7,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,2,0.004075369,0.217301757,0.12764772,0.010845963,0.147513616,0.004932524,5.10E-07,0.487682541,0,0,0.021648923,0.022225746,0,0.221950913,0,0.002192122,0,0,0,0.031367877,0,0.064232161,0.012991405,0.253723841,0.012153007,0.00170767,0.02840326,0,0,0.157403077,0.83,3824.192222,6771.601901,10595.79412,0.363324137,-0.818,-0.696,1.18,0.51,-0.09,1.19,0.81,-0.73,0.25,1.23,0.39,-0.31,1.61,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,1.55E-05,0.167869834,CNV_LOW,1.257412782,-0.041422012,-0.044486227,-0.047764927,0,0,0.000446531,0.346200922,0.449105173,0.204693905,MSS,No,WT,WT,1.59090564,1.417826394,0.42283286,6.044394119,5.781359714,3.584962501,CNV_low,12.96296296,7.407407407,61.11111111,7.407407407,3.703703704,7.407407407,Blood_normal,5b8ab142-f4da-4643-8c68-db13cfd072b2_gdc_realn.bam,c715d91e-8c73-4dfb-8bc8-7b40b85a66c3,Tumor,112790c0-190c-469d-9a8f-27abdcd1bea6_gdc_realn.bam,6ac5dcc3-1579-4f8f-9974-8183e970c433,Blood_normal,30d98464-2799-4a96-ac54-29b14e1512cc,Tumor,8396af38-2c13-409d-a101-ea1a579fc1e7,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_CTTGTA_S4_L006_R1_001.fastq.gz,433f4fc5-843a-4a1b-b993-dd413244a03f,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_CTTGTA_S4_L006_R2_001.fastq.gz,0ad8238f-6db6-42c0-ae96-4d7a5f0e7e7b,Tumor,92d49cdb-841a-47dd-8ff1-41957f9c5ddd,YES,PASS +S030,C3L-00781,No,4,16,127N,C3L-00781-04,CPT0070260003,Tumor,No,Other_specify,FIGO grade 3,50 % or more,Endometrioid,YES,Normal,pT2 (FIGO II),pN0,cM0,No pathologic evidence of distant metastasis,Stage II,II,1,71.09,48,No,White,Hispanic or Latino,Female,"Other, specify",Anterior and Posterior Endometrium,Unifocal,5.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Loss of nuclear expression,Loss of nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,4 or more,0.005420698,0.189251581,0.194236095,0.019354278,0.076433938,0.003331587,1.25E-09,0.511971821,0.030621947,0,0.057724868,0.128965836,0,0.359625849,0.017896475,0.027238232,0,0.003992697,0,0.002789135,0.027796018,0.026623532,0.047401521,0.10620711,0.003669428,0.041396454,0,0.031426484,0.008152597,0.028471817,0.95,4745.871875,6643.16418,11389.03605,0.521439556,-0.437,-0.387,0.47,1.46,-0.81,-0.26,0.3,1.46,0.46,-0.38,-0.11,0.05,-0.42,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,1,0,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0.052006459,0.000146769,CNV_LOW,0.400215642,-1.54E-05,-0.000658373,-0.000764994,0.016533914,0.022152841,0.021908213,0.26933117,0.482803588,0.247865242,MSI-H,No,WT,Frame_Shift_Del_Nonsense_Mutation,5.315549182,4.80079975,3.694931928,10.29347165,9.763212367,8.596189756,MSI-H,12.21198157,2.304147465,60.59907834,19.93087558,3.456221198,1.497695853,Blood_normal,f66e9c98-6bf9-401d-908e-6647373ab6ec_gdc_realn.bam,337eceaf-f9ad-4aca-8ba6-501faf696188,Tumor,10716ab4-7a85-4ad5-a1e0-ff7e1339aa0a_gdc_realn.bam,44dc38c6-1db6-4fe2-9a78-154b71409bbd,Blood_normal,a0b19c7e-733f-460c-969d-2e6954549afb,Tumor,c118fa04-a798-4523-b02f-4f292c61f47c,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_CGTACG_S9_L003_R1_001.fastq.gz,0de24a9c-ebaa-45df-8405-9c753dce28b2,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_CGTACG_S9_L003_R2_001.fastq.gz,8fe73704-391c-40df-b4ed-7ddab091670b,NA,NA,YES,PASS +S031,C3L-00905,No,3,10,130C,C3L-00905-02,CPT0063380003,Tumor,No,United States,FIGO grade 3,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN1 (FIGO IIIC1),Staging Incomplete,No pathologic evidence of distant metastasis,Stage III,IIIC1,1,44.81,64,No,White,Not-Hispanic or Latino,Female,"Other, specify",anterior and posterior,Unifocal,4.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,Unknown,0.004029459,0.052128545,0.12915044,0.04469791,0.0968925,0.00140797,9.64E-09,0.671693166,0.007473998,0,7.00E-04,0.011836886,0,0.053273559,0,0.006965088,0.009822934,0,0,0.029367134,0,0.160223537,2.00E-04,0.010375886,0,0.048482686,0.011250673,0,0,0,0.35,2073.093302,4354.875244,6427.968547,0.697873521,-0.134,-0.145,0.97,0.55,1.57,0.36,-0.47,1.2,-0.13,-0.05,-0.41,1.49,-0.99,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0.491688464,0.138666321,CNV_HIGH,5.92206939,-0.007832131,-0.000201005,-0.215851256,0.131320241,0.112848771,0,0.133461604,0.647566516,0.21897188,MSS,No,WT,WT,1.434447489,1.349358266,0.207641466,5.807354922,5.672425342,2.584962501,CNV_high,20,12,42,14,8,4,Blood_normal,609e24b7-042b-4088-a100-b55d5f0beaf5_gdc_realn.bam,faace15d-2171-48b5-9abb-8eb89ca66633,Tumor,d678d221-9dbd-4e9f-8f94-9aaef5f7092f_gdc_realn.bam,e6585c40-504d-419a-b31d-bacbfadc10da,Blood_normal,8db9ff3a-558c-4fdb-88e7-310c92350b3b,Tumor,239efdc5-6656-41bd-acd4-c6ba3c99c4d0,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_GCCAAT_S2_L001_R1_001.fastq.gz,f8d21c9d-a65c-4aba-9cae-71eadbe611ff,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_GCCAAT_S2_L001_R2_001.fastq.gz,b84dc177-6c03-40d2-ae16-83bb9e772349,Tumor,62486e0a-5e3b-4d0d-9e5f-2ffa6553122e,YES,PASS +S032,C3L-00918,No,2,7,131,C3L-00918-01,CPT0063790003,Tumor,No,Other_specify,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,No pathologic evidence of distant metastasis,Stage I,IA,1,43,68,Yes,White,Not-Hispanic or Latino,Female,"Other, specify",Both anterior and posterior endometrium,Unifocal,3,Cannot be determined,NA,Cannot be determined,NA,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,NA,Present,2,0.004322812,0.101417864,0.102821213,0.033989272,0.103538262,0.004822916,2.43E-08,0.649087637,0.026238122,0,0.013975788,0.006103286,0,0.247713667,0,0.096956018,0,0,0,0.074014313,0.013321546,0.037066542,0.063111119,0.113943164,0.030006631,0.024126845,0,0.046995801,0.040648716,0.035778439,0.87,4019.134039,6164.963056,10184.09709,0.491566743,-0.434,-0.122,1.59,0.67,1.11,0.36,1.14,0.06,0.12,1.21,0.41,0.19,1.32,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,1,1,0,0,0,0.018025661,3.33E-08,CNV_LOW,0.380049798,-0.00506506,-0.008649932,-0.011127615,0.001422013,0.002063857,0.004073356,0.172595657,0.476333232,0.351071112,MSI-H,No,WT,WT,3.667073084,3.1479216,2.274711708,8.566054038,7.994353437,6.965784285,MSI-H,15.7480315,2.755905512,56.2992126,17.71653543,3.149606299,4.330708661,Blood_normal,58bc0d8e-4cae-4a40-bc4a-2025637ff81d_gdc_realn.bam,b667c012-ee1a-4ddc-aee2-81635b8e37f4,Tumor,2d192478-8285-48eb-855b-40b8ce2a42a0_gdc_realn.bam,dbc8d39f-66cc-4ec1-8988-d6997c19f80d,Blood_normal,c04969da-c28a-4e6b-9b1a-cec0d56df395,Tumor,10d59b04-f3be-4df0-a5ad-217de279d020,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_CTTGTA_S7_L008_R1_001.fastq.gz,3d47af04-fe23-4f4d-8ec2-66420dd82fef,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_CTTGTA_S7_L008_R2_001.fastq.gz,83a66e82-d19f-4dcd-bf04-33397c2160a9,Tumor,48c97656-0509-49aa-aa9c-69f8407e0704,YES,PASS +S033,C3L-00921,No,4,15,128C,"C3L-00921-02,C3L-00921-03",CPT0064150004,Tumor,No,United States,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT2 (FIGO II),pN0,cM0,No pathologic evidence of distant metastasis,Stage II,II,1,32.32,66,No,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior,Unifocal,4,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,3,0.006487549,0.065319095,0.13841229,0.039595057,0.052963288,0.002937646,1.74E-09,0.694285073,0.015676172,0,1.00E-04,0.064132247,0,0.414372638,3.00E-04,0,0,0,0.073868667,0,0.015968111,0.015992922,0.02439787,0.229949042,0.030731553,0.006704016,0,0.045033677,0.019763217,0.013000122,0.97,4267.943026,5550.608927,9818.551954,0.509315266,0.35,-0.0653,-1.3,-0.31,-1.23,-0.4,-0.45,1.32,0.33,0.07,0.28,-0.28,-0.04,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.075161896,0.167332085,CNV_LOW,2.04679354,-0.043062122,-0.045147436,-0.04007455,0.008340476,0.000435609,0,0.107124413,0.428986832,0.463888755,MSS,No,WT,WT,1.295786701,1.2211157,0.168435383,5.584962501,5.459431619,2.321928095,CNV_low,13.95348837,6.976744186,62.79069767,2.325581395,0,13.95348837,Blood_normal,5af0168b-bb1a-4771-a478-cb4f8ec8fde8_gdc_realn.bam,2bb81d8c-9d4e-441e-ad35-b5c5474a8559,Tumor,b9d8510c-3b0e-49fb-98a3-c7db2cd05da7_gdc_realn.bam,08f80502-5363-432c-93ae-25f87330cf9e,Blood_normal,4d726701-04ed-4a0a-bcab-495568a316e5,Tumor,fa13139a-3e2c-49cd-9318-1d7dc55f2f19,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_CTTGTA_S7_L003_R1_001.fastq.gz,c8ac958e-2e20-4379-9568-7cc508e311de,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_CTTGTA_S7_L003_R2_001.fastq.gz,e292b646-ce77-45a1-a535-cb0dd26898e8,Tumor,c87d6095-66a7-4f45-8149-609a893df913,YES,PASS +S034,C3L-00932,No,2,8,128C,C3L-00932-01,CPT0027120003,Tumor,No,Other_specify,FIGO grade 2,Not identified,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,47.82,67,No,White,Not-Hispanic or Latino,Female,"Other, specify",left cornu,Unifocal,1,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,3,0.004444401,0.141805626,0.085956044,0.04509666,0.117913805,0.001916371,5.28E-09,0.602867088,0,0,0.003502029,0.082780907,0,0.095558177,0,0.029154427,4.00E-04,0,0,0.02872328,0.005956481,0,0.016122823,0.120844083,0,0.003705692,0.076648017,0,0.006576348,0,0.47,4455.576971,4402.548423,8858.125394,0.340425353,0.696,1.28,-1.33,-0.46,-0.7,-0.89,-1.29,-2.22,0.4,-1.34,-0.6,-0.78,-0.47,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3.76E-05,0.035198403,CNV_LOW,0.215064437,-0.000648148,-0.002843947,-0.007270925,0.124562884,0,0,0.034227034,0.250955331,0.714817635,MSS,No,WT,WT,2.603454103,2.246751627,1.2211157,7.366322214,6.930737338,5.459431619,CNV_low,16.52892562,5.785123967,60.33057851,10.74380165,4.958677686,1.652892562,Blood_normal,2b46f8aa-89b0-472b-969d-2ddd7b6266a5_gdc_realn.bam,727b0893-cc84-4b7e-b139-ea00f0a60d42,Tumor,6fea7283-a05f-4452-bcfc-4489af212782_gdc_realn.bam,9dbeb6c5-ec18-4cda-b9a0-170ac1f547ac,Blood_normal,81b1a4f5-dcab-4985-bdda-f1dfbca21017,Tumor,c1e1965b-85d8-40d2-a084-afa2886d1da3,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_CTTGTA_S13_L004_R1_001.fastq.gz,dd5354a9-7c2a-48a3-8381-96ed8ee9ea08,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_CTTGTA_S13_L004_R2_001.fastq.gz,14fc8a67-8464-475b-9c69-0ab40757f0d7,Tumor,5fff0072-1273-4d96-b935-981bdae15727,YES,PASS +S035,C3L-00938,Yes,4,15,129C,C3L-00938-01,CPT0016260003,Tumor,No,Other_specify,FIGO grade 2,50 % or more,Endometrioid,YES,Low,pT1b (FIGO IB),pNX,Staging Incomplete,Staging Incomplete,Stage I,IB,1,45.53,53,No,White,Not reported,Female,"Other, specify",both anterior and posterior,Unifocal,5.5,Cannot be determined,NA,Cannot be determined,NA,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,NA,Present,1,0.006872997,0.335080023,0.123591418,0.051605789,0.184967556,0.007488289,3.65E-09,0.290393925,0.00842545,0,0.017126022,0.067062409,0,0.116555551,0,0.012975359,0,0.020200039,0,0.027592607,0.030691074,0,0.075508375,0.140170374,0.042521713,0,0.081171027,0,0,0,0.64,8257.35682,8516.249705,16773.60652,0.163635965,-0.35,0.484,-0.81,-1.13,0.63,-1.17,0.13,-1.66,2.41,-0.18,2.12,-1.49,-1.4,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.053955297,0.110651098,CNV_LOW,NA,0,-0.005297803,-0.006504151,0.017870334,0,0,0.213855098,0.081698938,0.704445963,MSS,No,WT,WT,1.240148892,1.037474705,0.389123498,5.491853096,5.129283017,3.459431619,CNV_low,5.882352941,14.70588235,38.23529412,35.29411765,2.941176471,2.941176471,Blood_normal,354aacf4-4f9f-4177-8882-d3f996822ad9_gdc_realn.bam,98c830a5-8735-4f5f-812d-3e7f7c3aa514,Tumor,56a3cbdb-5dad-4d22-af0f-f56075c412b9_gdc_realn.bam,94e9963b-ecb8-490c-854c-2043f19224f1,Blood_normal,382e74bf-0a8c-439e-95c7-88d8d22024fc,Tumor,e4e1ff6a-e89a-4351-969b-1d7c583f21f4,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_CCGTCC_S3_L001_R1_001.fastq.gz,893adafa-41f8-4469-9c19-4b3c91b82e20,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_CCGTCC_S3_L001_R2_001.fastq.gz,aafe7ff3-0502-4175-a4a9-887ae8c2ec5b,Tumor,ef097688-a892-422e-9738-d16960061229,YES,Failed +S036,C3L-00942,No,1,3,130C,C3L-00942-01,CPT0016830003,Tumor,No,Other_specify,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,Staging Incomplete,Staging Incomplete,Stage I,IA,0,31.58,64,No,White,Not reported,Female,Anterior endometrium,NA,Unifocal,4.5,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,None,0.005177041,0.12990102,0.131887618,0.033872945,0.080990031,0.003407333,4.10E-08,0.61476397,4.00E-04,0.002365816,0,0.123466351,0,0.20566446,0,0.047263698,0.010235752,0,0,0.04054915,0.030148189,0.095737426,0.041096529,0.124492647,0.012869295,0.002002463,0.05073331,0,0.012958822,0,0.8,3909.219425,6057.850781,9967.070206,0.420444125,0.569,0.8,-1,-0.91,-0.35,-0.2,0.05,-1.52,0.29,-0.26,0.46,-0.98,0.2,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018025661,0.041968396,CNV_LOW,0.730471136,-0.000222039,0,-0.018111091,0.426543057,0.01139247,0,0.142267913,0.404198571,0.453533516,MSS,No,WT,WT,2.218238939,1.967248569,0.801600757,6.894817763,6.569855608,4.64385619,CNV_low,14.89361702,3.191489362,58.5106383,15.95744681,3.191489362,4.255319149,Blood_normal,3bf4671c-36c5-4987-a7f4-7afefe6422cf_gdc_realn.bam,06ebf4f1-4419-4dc0-a0c5-cf71457d6008,Tumor,c87a0a06-a7c7-46b7-acf9-42ee5469ff63_gdc_realn.bam,408ac551-237e-4ba3-8fe9-f9dc6c007ad6,Blood_normal,e1b5b9a4-609d-4bb6-a61e-c0c9e499f9ef,Tumor,b3f61b74-c4f8-4a05-883f-9e04a3b70cdb,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_TTAGGC_S14_L008_R1_001.fastq.gz,34b5b547-c104-4c3b-b809-8c5fc7bf841d,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_TTAGGC_S14_L008_R2_001.fastq.gz,54fe3f69-db4c-4bb1-bfe6-957aab9aaf4b,Tumor,342b1f84-56a5-42a4-a813-8f6ea9b7ae33,YES,PASS +S037,C3L-00946,No,1,4,130N,C3L-00946-01,CPT0027520003,Tumor,No,Other_specify,FIGO grade 1,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN0,Staging Incomplete,Staging Incomplete,Stage I,IB,1,17.64,64,No,White,Not reported,Female,Posterior endometrium,NA,Multifocal,3.9,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,1,0.004359049,0.102365644,0.094506407,0.032133044,0.094765293,0.003602011,8.38E-09,0.668268543,0,0,0.00172655,0.049229317,0,0.167282206,0,0.045841298,0,0,0,0.105500717,0,0.051160224,0.040816315,0.174904075,0.00363144,0.014442484,0,0.056142168,0,0.239323207,0.95,4238.332575,5643.777667,9882.110241,0.549858229,-0.284,-0.184,1.47,0.78,1.33,1.35,1.13,1.12,0.37,1.3,-0.67,1.52,1.02,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,1.40E-06,0.035134947,CNV_LOW,0.459632928,-0.001213574,-0.008244015,-0.017806263,0.284680929,0,0,0.154403781,0.510604207,0.334992012,MSI-H,No,WT,WT,4.821482763,4.333716157,3.187681472,9.784634846,9.276124405,8.038918989,MSI-H,20.03231018,2.423263328,55.25040388,14.70113086,4.36187399,3.231017771,Blood_normal,e1096e9c-9941-455a-861b-af3afbfaf88d_gdc_realn.bam,ae16fac3-238d-44ad-8b5f-c41ad8f2a58c,Tumor,49c45165-41d4-4682-b984-8dee018efa9a_gdc_realn.bam,9f7c16e3-2d73-42a0-9d4b-61270a1169d9,Blood_normal,8b361ca4-6848-4ba3-9c16-5c2cf1872ff4,Tumor,ba76dbf1-372a-4b71-aaac-d4c267ebbaa3,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_ATCACG_S2_L001_R1_001.fastq.gz,dd5912cb-695c-487b-9267-291f8ebb54bb,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_ATCACG_S2_L001_R2_001.fastq.gz,39a421b8-2826-44af-8ee6-af72e9a27cfa,Tumor,e3689d95-7cee-4906-9555-7bca7550557b,YES,PASS +S038,C3L-00947,No,1,1,129N,C3L-00947-01,CPT0027420003,Tumor,No,Other_specify,FIGO grade 2,Not identified,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,36.84,71,Yes,White,Not reported,Female,Posterior endometrium,NA,Multifocal,1.8,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,2,0.004528554,0.039355715,0.085921464,0.044274755,0.13572922,0.004577919,1.35E-08,0.685612359,0.029244357,0,0.089815096,0.089063113,0,0.15312548,0,0.070066347,0,0.0128425,0,0.050743363,0.054421936,0,0.032144626,0.208800355,0.005772881,0.005438661,0.046598774,0,0.017523387,0.004399126,0.87,2629.892485,5752.438575,8382.33106,0.486689804,-0.304,0.0228,0.67,0.33,-0.44,1.01,-0.25,0.3,0.61,-0.44,-0.27,-0.96,0.84,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0.001969706,3.50E-05,CNV_LOW,0.067541355,0,0,0,0.003398339,0.002129629,0.001831731,0.168378061,0.608515395,0.223106544,MSS,No,WT,WT,1.46712601,1.434447489,0.086674411,5.857980995,5.807354922,1.584962501,CNV_low,27.27272727,12.72727273,40,7.272727273,9.090909091,3.636363636,Blood_normal,151447ea-0a29-4f5b-b2b5-c844ecd8e530_gdc_realn.bam,0a956166-4f53-45a7-afcd-27ff6a956bb4,Tumor,8d88f32c-d396-4335-a5bf-6071ae72e740_gdc_realn.bam,d60d7a82-029f-47bc-82b9-0bdd09cbb8f3,Blood_normal,f09df81d-7521-4c7f-ade2-c7c64f7f6146,Tumor,766f7db5-1abd-45f6-b662-27fd77070be2,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_ATTCCT_S5_L002_R1_001.fastq.gz,989082f5-abb2-4d47-a6b3-e3560b9b38d3,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_ATTCCT_S5_L002_R2_001.fastq.gz,8d9b3ee8-b37d-4e67-856c-149dcd51f602,Tumor,e5c5a5b0-9951-49b1-ae6d-1da6f9ad75e7,YES,PASS +S039,C3L-00949,No,1,2,130C,C3L-00949-01,CPT0016370003,Tumor,No,Other_specify,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,Staging Incomplete,Staging Incomplete,Stage I,IA,1,37.69,64,Yes,White,Not reported,Female,"Other, specify",along anterior and posterior surface,Unifocal,2.5,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,2,0.005098513,0.118553064,0.118607577,0.047321103,0.091623186,0.002330233,2.73E-09,0.616466321,0.014017651,0,0.006541175,0.065985323,0,0.172918892,0,0,0.00687843,0,0.016716326,0.00110555,0.010850501,0.00770542,0.004253386,0.130015737,0.01803949,0.006207267,0.028764852,0,0,0,0.49,4333.499845,4851.094335,9184.59418,0.342228576,0.667,0.864,-1.04,-0.47,-0.81,-1.05,-1.1,-0.25,0.71,-0.59,-0.31,-1.13,-0.31,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.04828426,CNV_LOW,0.557054701,-0.014771766,-0.007665712,-0.012735819,0,0,0,0.045648765,0.417360147,0.536991088,MSS,No,WT,WT,1.483191823,1.383998466,0.245810227,5.882643049,5.727920455,2.807354922,CNV_low,21.15384615,9.615384615,50,13.46153846,3.846153846,1.923076923,Blood_normal,ff9ecfd3-1cb1-4fbc-b644-7060d84c4df2_gdc_realn.bam,6dd56638-c056-487f-a7fe-f446da41b8e2,Tumor,b4f80061-4d26-41c1-9931-7423d6eb4b8a_gdc_realn.bam,182fea04-02cf-4d59-a7b5-ea460b167acc,Blood_normal,bb4ccd90-f05f-48bc-b1bf-31420ea52bff,Tumor,f027559a-6562-4a93-a278-256e1a8d6bf7,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_CAGATC_S5_L008_R1_001.fastq.gz,acc81064-08f0-457b-9629-1bb742e4ceb6,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_CAGATC_S5_L008_R2_001.fastq.gz,1e750be5-488d-4a05-9c08-928700638328,Tumor,c7086fa4-9b10-4c98-b740-4738c4ae16c2,YES,PASS +S040,C3L-00961,No,2,8,131,C3L-00961-01,CPT0027320003,Tumor,No,Other_specify,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,28.5,59,No,White,Not reported,Female,Anterior endometrium,NA,Multifocal,4.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Absent,2,0.004460847,0.138551785,0.109482646,0.040021967,0.080876696,0.003183905,2.78E-09,0.623422151,0.010868604,0,0.007948338,0.109885559,0,0.36866113,0,0.073904574,0,0,0,0.03239514,0,0.083275431,0.064399209,0.179213063,0.014219009,0.060779007,0.034147031,0,0.02579255,0.074511355,1.14,5102.751057,5768.565065,10871.31612,0.397233013,0.203,0.661,-1.02,-0.52,0.98,-0.79,0.25,0.47,0.31,0.16,0.08,-0.72,0.09,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018025661,0.064640447,CNV_LOW,0.321551621,-0.008686236,-0.004589812,-0.000740079,0,0,2.15E-05,0.113551357,0.22946024,0.656988404,MSS,No,WT,WT,1.417826394,1.313865823,0.245810227,5.781359714,5.614709844,2.807354922,CNV_low,10.41666667,2.083333333,75,10.41666667,2.083333333,0,Blood_normal,2ebebf6f-5324-4914-b811-16b21e534c86_gdc_realn.bam,4d3a50d1-30e2-41fa-bea1-18e48bb47d4f,Tumor,56a0a87f-0053-436e-be1c-a0a3c975e19e_gdc_realn.bam,266c147a-cbf1-4b6d-8bb7-2497f2ad9013,Blood_normal,7ede6f1d-f31a-4122-b9a4-efec55776a69,Tumor,2c79d829-0805-426f-bde9-d7862506dc75,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_ACTGAT_S4_L002_R1_001.fastq.gz,339ad507-4d3e-4c9e-ae1c-5a207645cf9b,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_ACTGAT_S4_L002_R2_001.fastq.gz,6af2d835-4e67-4d59-9cf9-da8f0d197f44,Tumor,e8e85df1-c1e5-4a83-a5d8-1d35e2cf6351,YES,PASS +S041,C3L-00963,No,2,8,129C,C3L-00963-01,CPT0016490003,Tumor,No,Other_specify,NA,50 % or more,Serous,YES,Normal,pT1b (FIGO IB),pNX,Staging Incomplete,Staging Incomplete,Stage I,IB,1,34.89,59,Yes,White,Not reported,Female,"Other, specify",along anterior and posterior surface,Unifocal,2.6,Positive,-1,Positive,-1,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of expression,Vimentin Negative HNF 1 Beta Negative WT 1 Focally positive,Cannot be determined,1,0.005209019,0.06407184,0.101627765,0.035251651,0.115537488,0.003356582,1.18E-09,0.674945653,0,0.007246349,0,0.078174173,0,0.190698911,0,0.044134912,0,0,0,0.10639045,0.002564539,0,0.050662903,0.152417514,0.005672928,0.07376121,0.052446093,0,0,0.045830018,0.81,3781.400158,6255.195762,10036.59592,0.662501033,-0.94,-0.601,0.02,-1.54,1.14,0.42,0.48,0.27,0.14,0.9,-0.99,-0.58,1.15,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0.248423835,0.095571936,CNV_HIGH,2.73147802,-0.003401977,-0.000550972,-0.011154762,0.020039557,0.162623864,0.046533793,0.221445079,0.279277989,0.499276932,MSS,No,WT,WT,1.277478143,1.201828046,0.168435383,5.554588852,5.426264755,2.321928095,CNV_high,26.19047619,14.28571429,47.61904762,4.761904762,7.142857143,0,Blood_normal,6bf834f1-56da-43d9-98d1-6430d3011f86_gdc_realn.bam,36a10350-2017-46dc-ae84-9d87036edd79,Tumor,8dd015d6-ae3a-40d5-bc79-798ae6e58d69_gdc_realn.bam,ab63ee96-3de7-40ee-92a4-1ca8a2bca48d,Blood_normal,1fc95228-bfef-4385-8139-e212a669da09,Tumor,5df1af76-66e7-4bf2-af84-e795e172fc9b,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_CTTGTA_S2_L007_R1_001.fastq.gz,1041d695-f7af-49a9-a30c-b81115bd4ea7,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_CTTGTA_S2_L007_R2_001.fastq.gz,dfa1ae1e-a25a-483a-8e30-29a16c5d9939,Tumor,a4951b84-43a1-4422-89fc-dfe9b6121efb,YES,PASS +S042,C3L-01246,No,2,7,127N,C3L-01246-01,CPT0080980003,Tumor,No,Other_specify,NA,under 50 %,Serous,YES,Normal,pT1a (FIGO IA),pN0,Staging Incomplete,Staging Incomplete,Stage I,IA,0,39.14,62,No,White,Not reported,Female,Posterior endometrium,NA,Unifocal,2.3,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,1,0.002196903,0.171428644,0.062381378,0.031593671,0.114757023,0.003184432,8.60E-09,0.614457941,0.03118917,0,0,0.015260895,0,0.079155671,0,0.023992102,0,0,0,0.024890194,0.041579984,0.008591921,0.060980028,0.0947925,0.017781494,0,0.05178604,0,0,0,0.45,5711.460988,4979.833929,10691.29492,0.480357661,-1.06,-0.484,0.23,-0.82,-0.03,0.62,-0.69,0.58,1.08,-0.45,-0.8,0.2,-2.16,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0.299821411,0.323246107,CNV_HIGH,2.835751595,-0.025528506,0,-0.160785654,0.028202121,0.203619111,0.002579581,0.11312731,0.209490344,0.677382346,MSS,No,WT,WT,1.530342916,1.499080695,0.086674411,5.95419631,5.906890596,1.584962501,CNV_high,13.55932203,22.03389831,40.6779661,8.474576271,1.694915254,13.55932203,Blood_normal,69f5bb55-732f-438f-bd16-8a465e97d464_gdc_realn.bam,e51f6394-96cc-4d48-954b-a578ccea4a6b,Tumor,a1aa4887-909b-4409-a7cb-96399f56632b_gdc_realn.bam,67ae0bf3-c217-40d2-9e0f-031c88d3d165,Blood_normal,2dac5fa1-c56c-4425-ba61-8270014816ca,Tumor,989fb585-18b1-4e94-8d2d-48cc86534d73,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_CTTGTA_S20_L005_R1_001.fastq.gz,150efab8-0b73-4f1e-be49-e317b0d739ee,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_CTTGTA_S20_L005_R2_001.fastq.gz,f5b7c2a1-9ed4-451e-880b-9ad37fda8ddb,NA,NA,YES,PASS +S043,C3L-01247,Yes,3,10,128N,C3L-01247-01,CPT0080700003,Tumor,No,Other_specify,NA,50 % or more,Serous,YES,Low,pT1b (FIGO IB),pN1 (FIGO IIIC1),Staging Incomplete,Staging Incomplete,Stage III,IIIC1,1,38.44,63,No,White,Not reported,Female,"Other, specify","If Other, specify: Tumor occupies 100% of endometrial surface",Unifocal,11,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,1,0.003136131,0.270098168,0.085891909,0.057038104,0.255350012,0.003692105,1.53E-09,0.324793568,0.020459611,0,0,0.038044018,0,0.145117849,0,0.02712678,0,0.032517355,0,0.046517276,0.027718393,0,0.04266191,0.126920318,0.043941888,0,0.093350416,0,0.005624186,0,0.65,6791.999903,6499.908029,13291.90793,0.125566453,0.4,0.812,-0.76,-1.25,0.11,-0.46,-0.42,-1.62,2.03,-0.47,0.72,-2.07,-0.54,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,0.202564688,0.250547398,CNV_HIGH,NA,-0.00384073,-0.01101206,-0.029228366,0,0,0.004175319,0.097496233,0.090973238,0.811530529,MSS,No,WT,WT,0.580489024,0.580489024,0,4.087462841,4.087462841,0,CNV_high,25,12.5,31.25,25,6.25,0,Blood_normal,75350a75-f96e-4de2-a8df-44298992a35d_gdc_realn.bam,7e9c5ca9-4e5b-475a-b3f9-beb59939743b,Tumor,18a5e367-653a-430f-95b3-4d6b504e6c55_gdc_realn.bam,faab2e37-4298-4c8d-9e97-f916b328eb3a,Blood_normal,9a71ebf5-d978-4980-8894-e3b597321b3f,Tumor,f8d1546e-8793-48a7-9853-31626061778f,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_TAGCTT_S18_L005_R1_001.fastq.gz,20f8e780-92e0-43e6-b7a4-6e84f39235c8,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_TAGCTT_S18_L005_R2_001.fastq.gz,340e18d4-ab3f-4a19-8efa-19a46955ea2f,Tumor,e1074569-5cd3-4f9f-9c26-770fd0f849ea,YES,Failed +S044,C3L-01248,No,1,1,130C,C3L-01248-01,CPT0080300003,Tumor,No,Other_specify,FIGO grade 1,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pNX,Staging Incomplete,Staging Incomplete,Stage II,IB,0,59.78,42,No,White,Not reported,Female,Posterior endometrium,NA,Unifocal,6.3,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,1,0.004866398,0.396427238,0.07116207,0.041579539,0.133829893,0.003523899,4.37E-08,0.348610921,0.014830874,0,0.046343582,0,0,0.124923504,0,0.061050076,0,0,0,0.054248224,0,0,0.016167916,0.123462338,0.004972786,0,0.097073479,0,0.00128331,0.105643912,0.65,6134.476114,6239.261385,12373.7375,0.210133745,-0.768,0.428,0.58,-0.02,-0.65,-0.03,0.17,-0.35,1.68,0.71,0.39,-1.07,1.14,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.062727583,CNV_LOW,0.112300954,-0.002417106,-0.000334779,-0.003088754,0,0,0,0.164944633,0.100259031,0.734796336,MSS,No,WT,WT,0.42283286,0.207641466,0.245810227,3.584962501,2.584962501,2.807354922,CNV_low,20,20,40,20,0,0,Blood_normal,4524e78f-96c8-41f1-a6a8-e96abbd54c27_gdc_realn.bam,2b85a1a0-d4be-4eb0-9424-4ad4d38c853e,Tumor,e014ed4a-7325-4e39-b236-f63b6a17e319_gdc_realn.bam,ec333f4b-3db0-4c11-a38f-4795b11bb47f,Blood_normal,9aae580f-d6ae-4920-8e2f-a249be96c57f,Tumor,3aa26966-41cf-4ab9-9446-0e19fa01b054,Tumor,170908_UNC31-K00269_0080_BHLJ52BBXX_CCGTCC_S24_L006_R1_001.fastq.gz,f19a6801-b116-4e0d-b755-5f72f604f648,Tumor,170908_UNC31-K00269_0080_BHLJ52BBXX_CCGTCC_S24_L006_R2_001.fastq.gz,848dfac4-6067-4a87-8e2c-887b5e4a3272,Tumor,cb40d16a-6ca7-4e7d-8d2b-9266a76d0a4d,YES,PASS +S045,C3L-01249,No,1,2,128C,C3L-01249-01,CPT0080880003,Tumor,No,Other_specify,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,Staging Incomplete,Staging Incomplete,Stage I,IA,0,38.89,65,No,White,Not reported,Female,"Other, specify",Tumor occupies 75% of endometrial surface,Unifocal,6.5,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,1,0.005506597,0.082586753,0.128255657,0.022851227,0.133562549,0.011554706,5.71E-09,0.615682507,0,0,0.058490698,0.047550012,0,0.186223789,0,0.034617457,0,0,0.019629646,0.00418142,0,0.106226948,0.018306136,0.213574815,0.02868622,0.02101373,0,0.014757236,0,0.266741893,1.02,4435.707788,7668.0101,12103.71789,0.295209837,-0.546,-0.936,1.66,0.31,0.44,1.23,1.37,0.66,0.72,1.72,1.47,-0.31,2.05,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.02005336,4.15E-05,CNV_LOW,0.108108442,-0.001843017,-0.002387141,-0.005517554,0.000652912,0.001237317,0.00079462,0.413698802,0.293810101,0.292491097,MSS,No,WT,WT,1.182279033,1.05907234,0.245810227,5.392317423,5.169925001,2.807354922,CNV_low,20,5.714285714,62.85714286,5.714285714,2.857142857,2.857142857,Blood_normal,a9dfb9b8-ccc8-4c7f-8658-9bc8098e270e_gdc_realn.bam,806818d2-ac05-4017-a2f5-56b1cd9f8c22,Tumor,03268ce1-fb36-4573-ae32-127e717098ac_gdc_realn.bam,cf4aa5f9-c779-4b63-a58a-11b5bcf1365c,Blood_normal,04c9b457-112e-4e52-ac06-eac47fa8a994,Tumor,cfac3e22-503c-461b-82b7-95451aa8dcf3,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_GGCTAC_S17_L005_R1_001.fastq.gz,5bdc0383-216a-479a-b641-502eed2b241a,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_GGCTAC_S17_L005_R2_001.fastq.gz,1e55bad8-2e97-4693-9859-81d5834c997f,Tumor,bf806330-6f4c-44e9-a142-609db29497cd,YES,PASS +S046,C3L-01252,No,1,1,128C,C3L-01252-01,CPT0080610003,Tumor,No,Other_specify,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,Staging Incomplete,Staging Incomplete,Stage I,IA,0,38.41,76,Yes,White,Not reported,Female,Posterior endometrium,NA,Unifocal,0.9,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,4 or more,0.006402477,0.137741651,0.158318728,0.038989869,0.12208323,0.005223646,2.99E-09,0.531240397,0.010769803,0.001,0,0.036872541,0,0.222912019,0,0.01494661,0,0.040490228,0,0.033949534,0.02840839,0,0.015098039,0.248352302,0,0.055190295,0.032160254,0.002601277,0,0.027284937,0.77,4965.604393,6434.325792,11399.93018,0.339926771,1.1,0.316,0.27,-1.26,0.08,0.36,0.66,-2.38,0.74,0.65,0.03,-0.94,1.29,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.003030803,0.018025661,CNV_LOW,0.506601471,-0.002370195,-0.008578778,-0.019031371,0.007044113,0.004247474,0.004817637,0.164304785,0.39622699,0.439468225,MSS,No,WT,WT,3.981739572,3.542277219,2.364182099,8.903881846,8.430452552,7.076815597,CNV_low,12.79069767,1.453488372,68.89534884,9.593023256,4.651162791,2.61627907,Blood_normal,a7a105df-d4f7-4bef-87b3-01819d8bcf0b_gdc_realn.bam,ca598d4d-9330-4293-9d63-45a5a19c02db,Tumor,006c3a0a-73c6-45b5-9520-cffaf0a8cbff_gdc_realn.bam,fcd8e9ca-8399-4824-9e79-e6c582f7dc53,Blood_normal,b738031e-17f5-4a3d-b10e-963d5cc0eab8,Tumor,0a71692b-69f2-4d45-9740-59e1b1025326,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_GATCAG_S19_L005_R1_001.fastq.gz,d36d42d2-afb4-4098-bac2-2c0d503c2f67,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_GATCAG_S19_L005_R2_001.fastq.gz,992384ee-8c0e-4c30-8732-561df93e281a,Tumor,c90896d0-97cb-4a71-b6f8-1be802fee673,YES,PASS +S047,C3L-01253,Yes,3,10,131,C3L-01253-01,CPT0080400003,Tumor,No,Other_specify,FIGO grade 2,50 % or more,Endometrioid,YES,Low,pT1b (FIGO IB),pN0,Staging Incomplete,Staging Incomplete,Stage I,IB,1,31.83,77,Yes,White,Not reported,Female,"Other, specify",Both anterior and posterior endometrium are remarkable for tumor,Unifocal,5,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,2,0.006663685,0.083032527,0.100995526,0.06542584,0.249481246,0.00262345,1.15E-08,0.491777716,5.00E-04,0,0.005305717,0.097284872,0,0.033678849,0,0.006521843,0,0,0,0.015883132,0.011483769,0,0.006033839,0.112393435,0,0.006194443,0.064674674,0,0,0,0.36,6515.371607,5528.531387,12043.90299,0.120884628,1.06,0.449,-2.52,-1.37,-0.18,-1.6,-1.25,-2.56,1.21,-1.52,-0.22,-1.83,-0.37,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.51771591,0.488554072,CNV_HIGH,NA,-0.000733573,0,0,0,0.000419021,0.002139666,0.021332253,-7.99E-18,0.978667747,MSS,No,WT,WT,0.086674411,0.086674411,0,1.584962501,1.584962501,0,CNV_high,0,0,50,50,0,0,Blood_normal,0ccc9616-79cc-4ff5-b33b-2eac15b4078d_gdc_realn.bam,b0341a83-609c-4901-ba96-f76af59d0ec9,Tumor,a22d7330-2df5-4cad-9469-65de69d006eb_gdc_realn.bam,b35bb305-3e5f-450b-b7d7-53063757be27,Blood_normal,b5ce9048-1883-4704-9b11-e8ac3738a5e9,Tumor,dc7fc77c-0ce3-4ae4-9800-583943850fe9,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_ACTTGA_S24_L006_R1_001.fastq.gz,947060cd-6c80-47b7-8330-3b0d802d9d50,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_ACTTGA_S24_L006_R2_001.fastq.gz,430e7fee-c564-4b6d-9c18-3249e79c57d1,Tumor,3229853d-cb9d-4a3f-8f68-f47a20af074e,YES,Failed +S048,C3L-01256,No,1,3,129C,C3L-01256-01,CPT0073450003,Tumor,No,Other_specify,FIGO grade 1,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN0,Staging Incomplete,Staging Incomplete,Stage I,IB,0,34.37,75,Yes,White,Not reported,Female,Anterior endometrium,NA,Unifocal,4.3,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,4 or more,0.006931651,0.10085879,0.117115467,0.045018409,0.091572847,0.005441517,4.85E-09,0.633061315,0.015292295,0,0.041585333,0.108651861,0,0.192326822,0,0,0,0,0,0.029434116,0.051242322,0,0.00987097,0.165327623,0.059757333,0.006758145,0.051687953,0.005498505,0,0.042566719,0.78,5548.489367,6298.298259,11846.78763,0.351910974,0.321,0.622,-0.99,-0.88,-0.14,-0.88,0.34,-0.53,0.89,0.54,1.19,-1.64,0.25,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.017570882,0.047402035,CNV_LOW,0.274624621,-0.006828509,-0.002305824,-0.005376077,0,0,0,0.138124857,0.144692723,0.71718242,MSS,No,WT,WT,1.121990524,1.037474705,0.168435383,5.285402219,5.129283017,2.321928095,CNV_low,20.58823529,2.941176471,58.82352941,5.882352941,2.941176471,8.823529412,Blood_normal,2df1178d-478f-43e4-9bb3-69c9cb9bc38e_gdc_realn.bam,709a7bc9-9f91-46a9-99e0-0f1f5c8879a1,Tumor,cb2e92de-4d9e-4273-bb97-d5310fd76b5b_gdc_realn.bam,e3ac065a-67d7-4f3d-a9ad-ea2a35806d87,Blood_normal,01b7fb65-f024-4aaa-8f7c-ae8d5457633a,Tumor,dfc183e0-7cd4-4b7d-b213-902bb7a9daee,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_ATGTCA_S23_L007_R1_001.fastq.gz,aafd76a4-f0d2-4e99-bc97-34a7f2c06846,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_ATGTCA_S23_L007_R2_001.fastq.gz,9c0ad385-aa72-4df1-a53b-57f77602a7d7,Tumor,60fc4dee-b19e-453c-9b74-a0f85adcc723,YES,PASS +S049,C3L-01257,No,2,7,128N,C3L-01257-01,CPT0073520003,Tumor,No,Other_specify,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,Staging Incomplete,Staging Incomplete,Stage I,IA,0,17.11,71,No,White,Not reported,Female,"Other, specify",Tumor involves 75% of endometrial cavity per diagnostic pathology report,Unifocal,8,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,2,0.007955392,0.030422016,0.136826018,0.035453503,0.063623215,0.007146413,2.80E-09,0.71857344,6.00E-04,0.014150682,0,0.109470307,0,0.155098137,0.062742251,0.081580939,0.00442106,0.022112668,0,0.027640251,0,0.145158987,0.070700628,0.279895555,0.006471643,0,0,0,0,0,0.98,3346.731612,7805.287716,11152.01933,0.743161118,0.0343,0.758,-0.75,0.83,-0.83,0.34,0.83,0.25,-1.44,0,1.14,-0.39,-0.58,1,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.020458729,0.014393735,CNV_LOW,0.56063435,-0.005789059,-0.006350382,-0.013075595,0.001938268,0.003173341,0.004985567,0.305938879,0.570248414,0.123812708,MSI-H,No,MS_indel,Frame_Shift_Del,4.093231531,3.576376116,2.618078608,9.022367813,8.46760555,7.383704292,MSI-H,12.18130312,5.949008499,63.45609065,15.01416431,1.416430595,1.983002833,Blood_normal,3db8446e-2099-484b-8423-a49189910b49_gdc_realn.bam,fd6b0c0e-dba4-47e8-aa1a-24b2a702de0e,Tumor,e2d35a3b-cb54-4f5f-a99f-5453033ff93f_gdc_realn.bam,bba2fa86-ecf4-484d-b7f8-d59cf9dd055c,Blood_normal,54d040a9-00d4-4a18-bad6-bdeaa1a758ba,Tumor,6caaa45a-4ac6-479c-adb2-e947066663f7,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_AGTTCC_S14_L004_R1_001.fastq.gz,7c9d4661-f204-4d60-b0da-9de70a2d29b7,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_AGTTCC_S14_L004_R2_001.fastq.gz,b802ec84-9a75-4c16-bf86-e3b4e2e29561,Tumor,6aff5f34-7ff5-46dc-bc4a-0a1c8f26c66a,YES,PASS +S050,C3L-01275,No,3,9,129C,C3L-01275-01,CPT0073730003,Tumor,No,Other_specify,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN0,Staging Incomplete,Staging Incomplete,Stage I,IB,1,32.06,65,No,Not Reported,Not reported,Female,"Other, specify",100 PERCENT OF ENDOMETRIAL SURFACE INVOLVED,Unifocal,5,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,Unknown,0.005730778,0.109255916,0.119170745,0.027176374,0.148295618,0.005005061,2.25E-09,0.585365506,0.019563355,0,0.050302654,0.029312715,0,0.117139625,0,0.033005898,0,0.023439594,0,0.02729506,0,0.11382124,0.019701249,0.18378076,0.016770321,0.008110889,0,0.129636775,0.015382924,0.042736941,0.83,5035.794842,6267.438479,11303.23332,0.447122775,-0.0349,-0.34,2.14,0.35,-0.57,2.01,1.36,-0.48,0.96,1.68,0.33,0.07,0.92,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,1,1,0.001338495,0.000348114,CNV_LOW,0.081096258,-0.00225703,0,-2.98E-05,0.000879966,0.003380363,0,0.178791861,0.38263115,0.438576989,MSI-H,No,WT,WT,5.123913178,4.570184685,3.59866904,10.09671515,9.523561956,8.491853096,MSI-H,13.19727891,2.176870748,58.0952381,21.36054422,2.993197279,2.176870748,Blood_normal,069a9d12-aaae-41f8-bcb3-4b2de10d0aec_gdc_realn.bam,8b94a041-a634-4162-8b99-11f5a880e871,Tumor,a9da5378-f198-4cde-a619-1b7834af72a6_gdc_realn.bam,dfa0615b-3d51-4baa-9381-5d7bd4140b88,Blood_normal,269d555e-a19b-42bf-81bf-4e0c26c978a4,Tumor,d3bcdff3-cc7d-4d33-8256-862a2135fca6,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GGCTAC_S1_L006_R1_001.fastq.gz,4b44bd70-9e38-452a-878f-4875577eaa2c,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GGCTAC_S1_L006_R2_001.fastq.gz,555f14f3-dae8-486d-8306-df6603731765,Tumor,609f19ba-1626-4b7f-a886-19a54da1c95d,YES,PASS +S051,C3L-01282,No,1,4,128C,C3L-01282-01,CPT0077650003,Tumor,No,United States,FIGO grade 3,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,No pathologic evidence of distant metastasis,Stage I,IA,1,31.96,64,No,White,Not-Hispanic or Latino,Female,Anterior endometrium,NA,Unifocal,3,Cannot be determined,NA,Cannot be determined,NA,Loss of nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of nuclear expression,Cannot be determined,NA,Present,Unknown,0.006071288,0.051567513,0.116252847,0.03522931,0.095754957,0.004295623,1.60E-09,0.69082846,0.008889822,0,0,0.145274304,0,0.151125497,0,0.073799185,0.00906967,0,0,0.05385969,0.023889679,0.027204716,0.070048837,0.168158407,0,0.002996522,0.079300673,0,0.016382998,0,0.83,3702.652027,5760.986958,9463.638986,0.613785706,0.209,-0.0404,-0.31,-1.64,1.01,-0.22,-0.06,-0.7,-0.1,-0.55,0.09,-0.51,-0.24,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.023242954,0.085416885,CNV_LOW,1.542454073,-0.003600071,-0.044166784,-0.050706515,0.566440807,0,0,0.153605478,0.502674298,0.343720225,MSI-H,No,WT,WT,4.964246973,4.530149616,3.187681472,9.932214752,9.481799432,8.038918989,MSI-H,15.96638655,1.820728291,47.75910364,24.92997199,5.322128852,4.201680672,Blood_normal,c7d1a1e3-525d-4ba3-85fe-f27b9c31a232_gdc_realn.bam,66b11653-2708-4457-a500-f5c599cdc2d0,Tumor,bdb69ab0-ab7e-42b7-a661-ddf5a6001729_gdc_realn.bam,17017778-73ee-4163-8c32-767f45e148d9,Blood_normal,2b3e454f-b10f-4fa3-be38-5be8b26150e4,Tumor,58cbc0e7-4448-4ecc-807e-f7386431c790,Tumor,170908_UNC31-K00269_0080_BHLJ52BBXX_AGTCAA_S23_L006_R1_001.fastq.gz,1055a2ed-0ffd-4a47-b98d-31f79271fecc,Tumor,170908_UNC31-K00269_0080_BHLJ52BBXX_AGTCAA_S23_L006_R2_001.fastq.gz,0d5983fb-0657-4a02-8a14-3606ea81b0d8,Tumor,1c741e52-cd71-4814-bb62-52ce7e4cdf2f,YES,PASS +S052,C3L-01284,Yes,3,11,131,C3L-01284-02,CPT0079570003,Tumor,No,NA,NA,NA,Carcinosarcoma,YES,Normal,NA,NA,NA,NA,NA,NA,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.569,-0.451,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,NA,NA,NA,NA,0,-0.00271626,-0.002577586,0.000548697,0,0,NA,NA,NA,MSS,No,WT,WT,1.015548827,0.993284573,0.043988012,5.087462841,5.044394119,1,NA,12.5,12.5,59.375,12.5,0,3.125,Blood_normal,3d32ea57-7403-4d6e-ad7a-c86faa54393d_gdc_realn.bam,7725038c-3433-45d5-bda4-1b5dd52a9b87,Tumor,f36e8c4a-0fc4-4b27-9629-d4838f7ba815_gdc_realn.bam,c5047b0d-9e91-41d3-bef5-ba35d086456d,Blood_normal,bd10e94b-b778-44a2-a1af-3caf087d274f,Tumor,a9b52bf6-4681-41a9-a3c9-5c13609de510,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GCCAAT_S18_L005_R1_001.fastq.gz,60c35ad5-8f48-49d5-b0a1-fb2f195c929d,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GCCAAT_S18_L005_R2_001.fastq.gz,d69c5f9f-e4a8-4596-82e9-53b579863bda,Tumor,d0e638e0-fb56-4706-8edc-50d05fcec0c2,YES,PASS +S053,C3L-01304,No,1,4,129C,C3L-01304-01,CPT0064210003,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,No pathologic evidence of distant metastasis,Stage I,IA,0,41.44,68,Yes,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior,Unifocal,3.7,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,3,0.00208603,0.045042235,0.101301135,0.169993489,0.109129131,0.00481661,4.92E-10,0.567631369,0,0,0.039919707,0.093416052,0,0.145822992,0.025389225,0.021802422,0,0.037699444,3.00E-04,0,0,0.02503175,0.077019546,0.202442392,0,0,0.071131317,0,0,0,0.74,3554.390593,6691.117149,10245.50774,0.524013536,-0.0754,0.608,-0.17,-1.19,0.1,-0.29,-0.66,-0.14,-0.39,-1.09,-0.63,-0.57,0.26,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,7.60E-05,0.000147956,CNV_LOW,0.658740375,-0.002380017,-0.001064044,-0.000937405,0.014794003,0.013065794,0.012025851,0.220275126,0.453568112,0.326156762,MSS,No,WT,WT,1.295786701,1.182279033,0.245810227,5.584962501,5.392317423,2.807354922,CNV_low,29.26829268,0,53.65853659,9.756097561,7.317073171,0,Blood_normal,3f01a5d9-4b5b-4aa5-a6db-3d2786936bde_gdc_realn.bam,abdfac63-1c07-4f0b-878b-e230e90fa27a,Tumor,3866d5e5-efed-427b-bc34-b5a9bb070eb6_gdc_realn.bam,3df8fea4-d4ec-484d-a89c-33fe123dedc8,Blood_normal,105d699b-2118-4678-8fe5-c056e33b374b,Tumor,f61a20f0-253a-4b03-822e-17e43cd61cd4,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_GTGGCC_S21_L006_R1_001.fastq.gz,2c0d1a81-0278-4dcf-99b1-8b846369e7a2,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_GTGGCC_S21_L006_R2_001.fastq.gz,06f5c317-1033-4c7a-b439-095b129762d6,Tumor,44aa28bf-2dbf-4a1a-a220-095a7a2d0d31,YES,PASS +S054,C3L-01307,No,1,4,127C,"C3L-01307-01,C3L-01307-03",CPT0064290004,Tumor,No,United States,FIGO grade 3,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM1,pM1,Stage IV,IVB,1,31.63,74,Yes,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior,Unifocal,3.5,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,3,0.012745927,0.069778323,0.190886091,0.06036526,0.131387928,0.003685652,3.73E-09,0.531150815,0,0.028690669,0.055970953,0.057892742,0,0.143980157,0,0.021676235,0.021983045,0,0,0.037878075,0,0.141429525,0.016577828,0.154202848,0,0.003833063,0.026757166,0,0,0.009127693,0.72,3821.608966,5924.849456,9746.458422,0.612209667,-0.0648,-0.344,-0.11,-0.37,0.72,-1.69,0.08,0.88,0.14,-0.07,0.11,-0.24,-0.49,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.281230088,0.009184245,CNV_HIGH,2.928653664,-0.001479407,0,-0.206222747,0.089327755,0.089442964,0.036590969,0.224253983,0.423044883,0.352701134,MSS,No,WT,WT,1.121990524,1.037474705,0.168435383,5.285402219,5.129283017,2.321928095,CNV_high,5.882352941,26.47058824,35.29411765,11.76470588,14.70588235,5.882352941,Blood_normal,40844e74-4b1b-46ff-a4ea-d8f743dce828_gdc_realn.bam,88cb812e-8dbb-4315-b15d-2209fadb6c43,Tumor,c764cdc8-80c6-4b7a-a170-309fe582f17e_gdc_realn.bam,25baf71c-839d-4432-9960-59f47e1c37d7,Blood_normal,ac906496-2d2a-4621-b8f6-c4ee338878d8,Tumor,ae515f49-8fe2-4239-a18a-241d6cb28f2d,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_GTTTCG_S23_L006_R1_001.fastq.gz,7eae300f-fe7f-4059-876c-659d575a8f34,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_GTTTCG_S23_L006_R2_001.fastq.gz,9ad113e3-3bed-4906-a9d0-adc6e81379b4,Tumor,c9019ece-4b77-4014-805d-3aa888d9df7b,YES,PASS +S055,C3L-01311,No,1,3,128N,C3L-01311-01,CPT0077770003,Tumor,No,United States,FIGO grade 1,Not identified,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,No pathologic evidence of distant metastasis,Stage I,IA,0,37.11,55,No,White,Not-Hispanic or Latino,Female,Anterior endometrium,NA,Unifocal,3,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,None,0.004215926,0.109470974,0.101517641,0.06007514,0.143556921,0.006587758,4.74E-09,0.574575636,0.005798878,0,0.022069207,0.109550741,0,0.077021852,0.032685341,0.079008992,0,0.044567053,0,0.054539991,0,0.031163318,0.076748995,0.104517526,0.003387154,0,0,0.008075333,9.00E-04,0,0.65,4282.074991,6666.469204,10948.54419,0.478476847,-0.296,0.383,0.89,-1.73,0.83,0.73,0.16,-0.35,-0.08,-0.42,-0.13,-0.11,-0.4,0,1,0,1,0,1,0,0,0,0,0,0,0,0,1,0,0,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,1,1,0,1,0.019980775,0,CNV_LOW,0.18174419,-0.01793059,0,0,0.002070001,0.005535154,0.01129473,0.111994798,0.59072105,0.297284152,MSS,Yes,WT,Missense_Mutation,6.473523558,6.465459001,0.580489024,11.47116713,11.46301341,4.087462841,POLE,33.98299079,0.212615167,44.22395464,6.236711552,1.240255138,14.10347271,Blood_normal,20730bb0-a420-4cc3-91ea-80c765ccd3cf_gdc_realn.bam,1186aea4-bfdd-45ef-bc0a-683c289fd617,Tumor,b56bd2bb-ba83-4a80-835e-1c42b477fb0a_gdc_realn.bam,b56d2614-afdd-4be1-8629-69a7cf24d6ce,Blood_normal,d373e6d9-c4a8-4c0b-953d-49aa71477f7f,Tumor,9b170866-2a3a-4ad9-bc1e-cf0d2804648c,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_ATTCCT_S12_L003_R1_001.fastq.gz,391b8dfd-1857-41ff-8af2-ea0830668f60,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_ATTCCT_S12_L003_R2_001.fastq.gz,5b4f8676-cead-4e7a-b932-58fb3d37f3a1,Tumor,85041653-41b9-4890-a61e-f635f4bc5a65,YES,PASS +S056,C3L-01312,No,2,5,130C,C3L-01312-01,CPT0063670003,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,Staging Incomplete,No pathologic evidence of distant metastasis,Stage I,IA,0,31.96,56,No,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and Posterior,Unifocal,4,Cannot be determined,NA,Cannot be determined,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Cannot be determined,NA,Cannot be determined,1,0.005863154,0.146545755,0.114493109,0.045626743,0.103001166,0.005458865,1.02E-09,0.579011207,0.016955087,0,0.024427266,0.092732909,0,0.22358277,0,0.010177208,0.009819622,0,0,0.079006224,0.015489192,0,0.024328606,0.208602464,0.007996144,0.003921947,0.017436486,0.005250649,0,0.030273428,0.77,4262.424062,6385.554716,10647.97878,0.359457749,0.19,0.314,0.25,-0.35,0.34,-0.17,0.4,-1.32,-0.06,0.43,0.82,-0.73,1.49,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.000224702,0.063228516,CNV_LOW,0.563707282,-0.016165776,-0.015521278,-0.016593224,0,0,0,0.158812029,0.426011719,0.415176252,MSS,No,WT,WT,1.295786701,1.142367912,0.319245674,5.584962501,5.321928095,3.169925001,CNV_low,20.51282051,2.564102564,53.84615385,12.82051282,5.128205128,5.128205128,Blood_normal,21d6d362-118e-4dfe-9130-7aeb1bf82058_gdc_realn.bam,142a53dc-3e84-4a26-8b71-e3c0926a54b7,Tumor,36a47ab1-152f-4078-855e-82e726b1778f_gdc_realn.bam,c03828a8-c41d-4fc6-a3ba-6ec5908a4f7a,Blood_normal,76e906be-7778-4801-9ae9-6200be0649d4,Tumor,5eacf3e4-6cc2-48d0-ac48-cdd70d4f591b,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_TAGCTT_S6_L008_R1_001.fastq.gz,bcbd006a-fd60-43db-905d-aa6e729f314a,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_TAGCTT_S6_L008_R2_001.fastq.gz,f3db77a2-db19-4942-8c2e-3b69f81a956b,Tumor,ef01f3f5-b7f4-4765-a579-804299a31ac2,YES,PASS +S057,C3L-01744,No,1,3,127N,C3L-01744-01,CPT0093280003,Tumor,No,Other_specify,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,Staging Incomplete,Staging Incomplete,Stage I,IA,0,46.45,62,No,White,Not reported,Female,Anterior endometrium,NA,Unifocal,2.2,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,2,0.007891409,0.030381439,0.131031212,0.044015107,0.054719455,0.003346583,7.56E-11,0.728614796,0.00669145,0,0.01279678,0.162358545,0,0.060144906,0,0.084212413,0.015350342,0,0.02209679,0.002045284,0.02761867,0,0.029584537,0.137049713,7.00E-04,0.007310619,0,0.030856792,0.011223627,0,0.61,1682.151896,5590.277688,7272.429584,0.935807315,-0.473,-1.08,-1.39,0.03,-0.76,-1.06,-0.36,0.9,-1.93,-1.22,-0.58,1.69,-0.52,1,1,0,1,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.01749751,0.000115682,CNV_LOW,0.402217982,-0.016802222,-0.004861285,-0.01133029,0.008267534,0.012597006,0.007949318,0.148952464,0.77235307,0.078694467,MSI-H,No,MS_indel,Frame_Shift_Del_Nonsense_Mutation,5.382393153,5.055718949,3.24062152,10.36194377,10.02652344,8.098032083,MSI-H,12.18809981,1.535508637,60.84452975,19.00191939,4.510556622,1.919385797,Blood_normal,e3b971ec-48d2-431f-ae8b-719525fa1716_wxs_gdc_realn.bam,8b2f6755-245b-40fc-907d-062a356a39f3,Tumor,f52882fc-8b4f-47c1-bd89-bf72d116b7e6_wxs_gdc_realn.bam,e3388e0d-3dd6-4fab-81e0-5fd54ced76b3,Blood_normal,59d5779f-3b81-49d3-9e1e-c081765a3df5,Tumor,551e9aca-4705-4f05-8d2a-8f2dbc11eff7,Tumor,171205_UNC32-K00270_0069_BHN2HGBBXX_ACTGAT_S22_L006_R1_001.fastq.gz,0eefe67a-b297-4c2f-87ad-d25b83e43a2b,Tumor,171205_UNC32-K00270_0069_BHN2HGBBXX_ACTGAT_S22_L006_R2_001.fastq.gz,6d97b258-2fc8-4b10-9c6c-d1e7dac46106,Tumor,25f6a3d7-9619-461e-923d-7276d0ab2925,YES,PASS +S058,C3L-01925,No,4,15,127N,C3L-01925-07,CPT0113690003,Tumor,No,United States,NA,50 % or more,Serous,YES,Normal,pT3b (FIGO IIIB),pN1 (FIGO IIIC1),Staging Incomplete,pM1,Stage IV,IVB,1,27.66,65,No,White,Not-Hispanic or Latino,Female,"Other, specify",Anterior and posterior endometrium,Unifocal,4.5,Positive,5,Negative,NA,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Intact nuclear expression,Loss of expression,"Ki-67, 57% ; positive for p16 (strong and diffuse), focally positive for CK5/6 and p40",Cannot be determined,None,0.003108123,0.245624092,0.052792773,0.013339386,0.100179506,0.001663694,1.86E-09,0.583292424,0.030012721,0,0.011458756,0.008603041,0,0.115811487,0,0.045137299,0,0,0,0.036534493,0.003605974,0.043674035,0.018902943,0.090333965,0,0.009959128,0.00596616,0,0,0,0.42,4255.959916,3163.142174,7419.10209,0.542145569,-1.46,-2.6,0.88,-0.19,-0.88,1.27,-1.49,0.4,1.67,-1.06,-1.29,0.04,-1.4,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.491125051,0.385955474,CNV_HIGH,5.48245768,-0.001048497,-0.005103458,-0.225720624,0.240745792,0.187988723,0.000426944,NA,NA,NA,MSS,No,WT,WT,1.162461482,1.080351414,0.168435383,5.357552005,5.209453366,2.321928095,CNV_high,22.22222222,19.44444444,36.11111111,13.88888889,2.777777778,5.555555556,Blood_normal,d354fd4a-1f75-4174-b0c9-10575ed3a4d5_wxs_gdc_realn.bam,ffc37f27-76c2-4df1-aaad-ed6f7d8e8ffb,Tumor,45a3f0fe-0662-4dfd-9f5e-f5b62faef683_wxs_gdc_realn.bam,dcefad95-d4c9-4736-b67e-7270c9e16673,Blood_normal,580c3cce-5125-41fd-933b-52017d1279e0,Tumor,70147939-557e-46d7-852f-38e1c1e7be31,Tumor,180508_UNC31-K00269_0128_BHTY7KBBXX_AGTCAA_S23_L006_R1_001.fastq.gz,49190371-ec2a-420f-a804-0931a346d206,Tumor,180508_UNC31-K00269_0128_BHTY7KBBXX_AGTCAA_S23_L006_R2_001.fastq.gz,c8dfbe14-a49c-4838-95c7-c9b9ed81633a,Tumor,78f10f4d-1533-4556-b43c-63bfb3734b02,NA,NA +S059,C3N-00151,No,4,16,129N,C3N-00151-03,CPT0066620003,Tumor,No,Ukraine,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN0,cM0,No pathologic evidence of distant metastasis,Stage I,IB,0,27.1,60,Unknown,NA,NA,Female,"Other, specify",Entire uterine cavity,Unifocal,NA,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,2,0.016229609,0.066982605,0.117841991,0.037353248,0.110029945,0.003059245,8.19E-09,0.648503347,0.124378981,0,0.041497227,0.086170937,0,0.178005848,0.016912327,0.096795497,0,0,0,0,0,0.059535132,0.079014882,0.08291912,0,0.005009947,0.018592465,0.019894683,0,0.031272954,0.84,3508.374749,6137.36728,9645.742029,0.655787215,-0.0747,-1.93,1.36,1.98,-0.21,1.69,1.29,0.42,-0.18,1.2,0.93,-0.14,0.44,1,0,0,0,0,1,0,1,1,1,0,0,1,0,1,0,1,0,0,1,1,1,0,1,1,1,0,0,0,0,1,0,1,1,1,1,3.63E-05,3.33E-08,CNV_LOW,0.138302686,0,0,-0.008060267,0.004694148,0.002273465,0,0.227748077,0.560807043,0.21144488,MSS,Yes,WT,WT,8.317776613,8.31441313,0.801600757,13.32685077,13.32347703,4.64385619,POLE,35.05365854,0.253658537,29.45365854,11.22926829,0.917073171,23.09268293,Blood_normal,8252f908-a17d-475a-a94f-88043f2bf9da_gdc_realn.bam,94cf10bc-d882-429b-8083-bd4123f3a4bc,Tumor,73dee08e-268f-4107-b55d-ee1906f078e6_gdc_realn.bam,5246a7b0-58b3-425b-9c84-dfe8a361fc81,Blood_normal,c8094cb6-306f-499b-861c-54292228468d,Tumor,fc38dc22-853e-41e9-a8c6-ab43e06b3179,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_TTAGGC_S8_L008_R1_001.fastq.gz,325918b9-3905-49ff-b4f6-f76a88e30301,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_TTAGGC_S8_L008_R2_001.fastq.gz,31961972-9d79-45d4-a53c-b80875dd8e9a,Tumor,cf69a580-e2e3-4c41-8c07-0650b78e3a08,YES,PASS +S060,C3N-00200,No,3,9,128N,C3N-00200-02,CPT0017870003,Tumor,No,United States,FIGO grade 2,Not identified,Endometrioid,YES,Normal,pT2 (FIGO II),pN1 (FIGO IIIC1),Staging Incomplete,Staging Incomplete,Stage III,IIIC1,NA,46.85,72,Yes,Black or African American,Not-Hispanic or Latino,Female,"Other, specify",anterior and posterior endometrial cavity,Multifocal,9,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,4 or more,0.003404556,0.437720749,0.069614216,0.034985182,0.080478688,0.003404118,1.24E-08,0.370392479,0.042572483,0,0.00647704,0.074472037,0,0.157712493,0,0.013428672,0,0,0,0.052652388,0.030101489,0,0,0.189955698,0,0.007935982,0.024691718,0,0,0,0.6,4684.861932,4838.564981,9523.426913,0.196347513,0.0985,0.924,-1.37,-0.7,-0.81,-0.78,-1.54,-1.05,1.24,-1.6,-0.18,-1.5,-0.6,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.000813962,CNV_LOW,0.172992111,0,-0.004818201,-0.003167805,0.003746224,0.000747792,0,0.025074678,0.322261222,0.6526641,MSS,No,WT,WT,1.162461482,1.080351414,0.168435383,5.357552005,5.209453366,2.321928095,CNV_low,19.44444444,8.333333333,38.88888889,22.22222222,0,11.11111111,Blood_normal,136eb1b9-e1da-4a4d-9637-708e3553ba64_gdc_realn.bam,1d2a42cf-e43c-4ded-8a10-c1c0cc85791a,Tumor,7c591788-4359-4ae7-8dc2-6342e4726baa_gdc_realn.bam,78de42e6-acc0-49ab-8879-7af689f912b0,Blood_normal,636910f0-d39e-4463-abd3-f7dafbbf34fc,Tumor,f5332af5-667a-4788-b6c5-0a2690c79255,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_AGTTCC_S22_L006_R1_001.fastq.gz,c9c50554-d2cc-4a32-a115-38a396a175f3,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_AGTTCC_S22_L006_R2_001.fastq.gz,95fff05f-06dc-4463-a6b9-9cb88669fe24,Tumor,27b931e5-a3dc-4832-ac62-798ba69bec62,YES,PASS +S061,C3N-00321,No,3,10,130N,C3N-00321-01,CPT0010260003,Tumor,Yes,Ukraine,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,26,64,No,NA,NA,Female,"Other, specify",Uterine cavity,Multifocal,1.5,Positive,80,Positive,30,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – positive; Vimentin (Vim3B4) – negative,Cannot be determined,2,0.007932213,0.076065268,0.137075172,0.043301072,0.081580986,0.003773438,1.06E-09,0.650271851,0.038086734,0,0.043384893,0.098087625,0,0.303072564,0,0.120657123,0.001645347,0.054679848,0,0.073224264,0,0,0.099611915,0.207091546,0.046680774,0,0.033777368,0,0,0,1.12,3627.437843,6229.435198,9856.873041,0.715241228,0.456,-1.67,-0.41,0.22,0.73,-0.34,-0.19,-1.06,-0.39,-0.7,0.08,-0.29,-0.31,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,1,0,0,0,1,0,0,0,0.012143202,0.035379732,CNV_LOW,0.723440323,-0.001605586,-0.004272987,-0.007245738,0.142891225,0.028710501,0,0.198948242,0.529494006,0.271557752,MSI-H,No,WT,Frame_Shift_Del_Nonsense_Mutation,5.050337259,4.572063684,3.371537285,10.02097994,9.525520809,8.243173983,MSI-H,13.85869565,1.222826087,60.73369565,19.29347826,3.260869565,1.630434783,Blood_normal,5af7cd9f-e8dd-49af-ac6a-6badeed9fd8d_gdc_realn.bam,215e2fdf-ca19-4def-9faf-067115d046d4,Tumor,1835754d-479f-4784-9083-921104cb7a68_gdc_realn.bam,e1661ddf-c57f-4d99-b859-53baacfb1010,Blood_normal,3a2749ed-da5e-477a-9cd4-900035dc627b,Tumor,da271d9f-79b1-40d3-8ccb-43eb62566689,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_ATCACG_S21_L007_R1_001.fastq.gz,0de8cfbb-adb2-4d1d-91f6-685a03b16449,Tumor,170802_UNC31-K00269_0072_AHK3GVBBXX_ATCACG_S21_L007_R2_001.fastq.gz,cc11b6d3-897f-4158-96a4-91b5ebbbb74e,Tumor,295d4951-f892-48a8-b1a5-eb1851ba67c5,YES,PASS +S062,C3N-00322,No,1,4,130C,C3N-00322-03,CPT0010430003,Tumor,Yes,Ukraine,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,31,70,No,NA,NA,Female,"Other, specify",Entire Uterine Cavity,Multifocal,2.6,Positive,85,Positive,50,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – positive; Vimentin (Vim3B4) – positive,Cannot be determined,2,0.004036411,0.022281501,0.093054629,0.03878787,0.038672923,0.001245467,2.01E-09,0.801921196,0.008844079,0,0.029447879,0.024497424,0,0.034506425,0,0.001711434,0,0,0,0.010084213,0,0.007519195,9.00E-04,0.047962606,0.002492303,0,0.032059529,0,0,0,0.2,2569.07483,3671.485686,6240.560516,0.625552677,0.548,0.371,-2.32,-0.05,-1.21,-0.87,-1.93,-1.48,-0.9,-1.42,-0.51,0.17,-0.31,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.078502133,0.073526732,CNV_LOW,0.700120616,-0.001714734,-0.002022706,-0.014190813,0.274251993,0,0,0.035279107,0.397792557,0.566928335,MSS,No,WT,WT,1.797751858,1.663200075,0.389123498,6.339850003,6.14974712,3.459431619,CNV_low,20,2.857142857,62.85714286,7.142857143,4.285714286,2.857142857,Blood_normal,57e730bf-2e32-4cf2-907b-f191778b6783_gdc_realn.bam,4989f40e-696b-41f9-bf68-f0b89e76f9b8,Tumor,dfc8a271-3680-4e17-a894-06841e360ef2_gdc_realn.bam,a60a9f62-9124-4a9d-8c28-1df22de7e053,Blood_normal,c44027d8-b828-4d83-b821-f9c8b1dcd844,Tumor,f3d0e5ea-1ad6-444e-884f-d198aab1f134,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_ATCACG_S5_L008_R1_001.fastq.gz,86f3b033-6491-4d96-bf41-f51ddfc6bb5b,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_ATCACG_S5_L008_R2_001.fastq.gz,258cde18-4abd-4a5f-8140-23f1da45abdc,Tumor,1dd7ae14-7d99-44f5-9361-078cdd43606a,YES,PASS +S063,C3N-00323,No,2,7,130C,C3N-00323-02,CPT0010610003,Tumor,Yes,Ukraine,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,27,78,No,NA,NA,Female,"Other, specify",Uterine cavity,Multifocal,4,Positive,90,Positive,20,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – positive; Vimentin (Vim3B4) – positive in myometrium,Cannot be determined,Unknown,0.006382884,0.061490059,0.148799843,0.050010993,0.12871576,0.002939082,4.63E-09,0.601661375,0,0,0.029467374,0.068410488,0,0.140721701,0,0,0.011763169,0,0.037773189,0,0,0.184708541,0.037899661,0.153705136,0,0,0.045550741,0,0,0,0.71,3740.58003,5246.146449,8986.72648,0.660090527,0.755,-1.15,-0.46,0.64,0.24,-1.34,-0.73,0.55,0.15,-0.78,0.99,-0.38,0.39,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.035623529,0.224999076,CNV_LOW,1.624050731,-0.00977493,-0.041093192,-0.007796096,0.190078055,0.051347771,0,0.210719013,0.356328585,0.432952402,MSS,No,WT,WT,1.560942049,1.514796483,0.128134019,6,5.930737338,2,CNV_low,15,5,66.66666667,3.333333333,6.666666667,3.333333333,Blood_normal,577c96fe-53aa-4c2d-9410-263e818b88d0_gdc_realn.bam,37e704ce-f3af-4ef0-ad64-d94fad73aa39,Tumor,5b342ae2-f869-4fb5-af0d-556559e43e54_gdc_realn.bam,ac736b73-851b-457f-a05b-ccd1cda0cf77,Blood_normal,f14df642-0372-4fce-98ae-e94369a425cd,Tumor,81a11798-0812-4fda-81fb-43b01a15f562,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_CGATGT_S6_L008_R1_001.fastq.gz,6c14578c-92ff-4085-a8d8-d5122ff4fd11,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_CGATGT_S6_L008_R2_001.fastq.gz,727a9891-1116-4c77-9787-a08111f0b3e8,NA,NA,YES,PASS +S064,C3N-00324,No,3,11,130C,C3N-00324-04,CPT0010820003,Tumor,Yes,Ukraine,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT2 (FIGO II),pN0,cM0,Staging Incomplete,Stage II,II,0,35,66,Yes,NA,NA,Female,"Other, specify",Uterine cavity,Multifocal,2.3,Positive,80,Positive,70,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – positive. Vimentin (Vim3B4) – positive.,Cannot be determined,Unknown,0.004926435,0.040904304,0.123258586,0.039417667,0.046900078,0.006079859,6.37E-09,0.738513065,0.01866044,0,0.001911367,0,0,0.292386957,0,0.014451686,0.002204626,0,0.017253413,0.018403697,0.013078051,0.045221132,0.019022007,0.182363781,0.065752505,0.049617216,0,0.013628498,0.010695738,0.045348883,0.81,3563.533329,6318.746917,9882.280246,0.633737159,-0.0921,0.0846,-0.35,0.1,1.52,-0.62,0.17,0.38,-0.91,0.73,0.86,0.58,1.31,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.000158276,CNV_LOW,0.816261462,-0.001916029,-0.002163191,-0.001009317,0.027806684,0.034279747,0.037680011,0.212727517,0.418050437,0.369222046,MSS,No,WT,WT,1.732044006,1.576001633,0.42283286,6.247927513,6.022367813,3.584962501,CNV_low,18.75,6.25,54.6875,14.0625,3.125,3.125,Blood_normal,cd24c578-62a3-4d17-bf84-b1c439977cce_gdc_realn.bam,1ce30c13-0c75-412b-86ee-5a951e7efb92,Tumor,5142f7db-1b0f-466b-bcb3-9704940ffdab_gdc_realn.bam,0aeb075f-7fad-4391-8773-a716e053eb2b,Blood_normal,913cfbfa-c656-4161-b42d-7d343b7cffeb,Tumor,417609db-9760-41da-af19-8258e8ab57ea,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_TTAGGC_S21_L008_R1_001.fastq.gz,a76e636b-9fd0-4cf2-b0c6-78ed366d7c3d,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_TTAGGC_S21_L008_R2_001.fastq.gz,ced11262-32d0-42c6-a91f-2d3f801ed551,Tumor,f6876ca4-bf05-46cb-8bf3-c2e1422e4765,YES,PASS +S065,C3N-00326,No,2,8,130C,C3N-00326-01,CPT0022530003,Tumor,Yes,Ukraine,FIGO grade 1,Not identified,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,35,45,No,NA,NA,Female,"Other, specify",Uterine cavity,Multifocal,1.3,Positive,95,Positive,90,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – focally positive; Vimentin (Vim3B4) – positive,Cannot be determined,2,0.004979518,0.065285664,0.097412193,0.041874395,0.044211258,0.001658171,5.17E-10,0.7445788,0,0,0.024248712,0.040886712,0,0.113361734,0,0.001274594,0.004202812,0,0.034001026,0,0,0.087850691,0.002384896,0.053377612,0.011314816,0.021351223,0,0.024953588,0.001495829,0.01927318,0.44,1840.583053,3796.214544,5636.797597,0.719228044,-0.846,0.474,-1.04,0.49,-0.41,-0.8,-0.82,1.58,-1.73,-0.59,-1.1,0.69,0.22,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018708803,0.000119261,CNV_LOW,0.046244824,0,0,0,0.000899662,0.002372009,0.001905127,0.12367529,0.595569786,0.280754924,MSS,No,WT,WT,0.801600757,0.610053482,0.282995148,4.64385619,4.169925001,3,CNV_low,29.41176471,5.882352941,47.05882353,5.882352941,5.882352941,5.882352941,Blood_normal,fe5e1dd1-ea01-4ff5-8019-c8d372a33339_gdc_realn.bam,4971ed33-2da8-4d91-97c1-31564e3e1796,Tumor,3fa66b09-0381-4234-9176-e70c8b4f7338_gdc_realn.bam,dad5a4fb-980f-4fac-a55f-19f43b41478b,Blood_normal,1d0fce2e-e790-4ff1-880b-67ecb7234d4b,Tumor,0dc37b55-fee6-4705-beab-1d4dfa5b3fd4,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_GATCAG_S8_L008_R1_001.fastq.gz,fd7cf324-b89a-4558-a03f-d64ef2be88ff,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_GATCAG_S8_L008_R2_001.fastq.gz,90917b44-0072-4cec-bd84-9dd8885045f0,Tumor,8fb25398-22bd-440b-9b8f-04559cd909bf,YES,PASS +S066,C3N-00328,No,3,12,130C,C3N-00328-05,CPT0019840003,Tumor,Yes,Ukraine,FIGO grade 3,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN0,cM0,Staging Incomplete,Stage I,IB,0,31.22,62,No,NA,NA,Female,"Other, specify",Uterine cavity,Multifocal,3,Positive,90,Positive,70,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – positive; Vimentin (Vim3B4) – positive;,Cannot be determined,Unknown,0.014894189,0.031289689,0.135733147,0.043499463,0.041931867,0.012644167,6.15E-10,0.720007478,0.003230715,0,0.091752351,0.16848275,0,0.103577841,0.263662345,0.083597209,0,0.004897877,0.080428803,0,0,0.063637704,0.194001873,0.285098088,0.004733789,0,0.002898656,0,0,0,1.35,4369.682108,9711.938731,14081.62084,0.861033458,-0.188,-0.643,0.06,-0.49,2.4,0.34,1.04,1.36,-1.47,-0.02,2.12,-0.82,-1.03,1,0,0,1,0,1,0,0,1,0,0,1,1,0,1,0,0,0,1,0,0,0,0,1,0,0,1,0,1,0,0,0,1,1,1,1,0.030018893,0.051935749,CNV_LOW,0.759519858,-0.004193273,-0.015025716,-0.02175412,0.166020994,0,0,0.490438133,0.36724791,0.142313957,MSS,Yes,WT,Missense_Mutation,7.571805466,7.567338041,0.667424661,12.57790084,12.57341051,4.321928095,POLE,45.14276337,0.393829997,35.28060387,5.562848704,0.918936659,12.70101739,Blood_normal,290e3a66-502c-40c7-b6cc-e4783b31bf23_gdc_realn.bam,92a6ecef-93d2-4e81-ba10-8c6fa21e412e,Tumor,4aec9b8e-d049-435a-8d3f-e17ee190dd8a_gdc_realn.bam,c1d2d417-5a50-4534-8ae1-fc69aca45772,Blood_normal,bdfcac24-2bb8-471f-ab8b-6fe9f1f10c3b,Tumor,6ba9f990-4d24-43fb-bf5b-1858a0146e7e,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_GCCAAT_S16_L004_R1_001.fastq.gz,1409ef12-3919-4b88-b5b8-4a85576fadc7,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_GCCAAT_S16_L004_R2_001.fastq.gz,fba3daa2-3a66-4af6-aa02-ff5cb8d534eb,Tumor,f18f7aa8-6d8a-4f1b-bf15-809bd5bfb5e5,YES,PASS +S067,C3N-00333,No,2,5,127N,C3N-00333-03,CPT0011000003,Tumor,Yes,Ukraine,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,31,65,No,NA,NA,Female,"Other, specify",Entire Uterine Cavity,Multifocal,1,Positive,70,Positive,50,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – positive; Vimentin (Vim3B4) – positive,Cannot be determined,Unknown,0.002296699,0.118953119,0.098801088,0.03362146,0.111089441,0.00527552,1.15E-09,0.629962672,0.016298314,0,0.00704365,0.01497689,0,0.069356038,0,0.009639726,0,0.047553185,0,0.020033554,0.051333479,0.093244702,0.008736583,0.090772415,0.01672796,0.022602173,0.050744634,0,0,9.00E-04,0.52,5520.164395,6014.318353,11534.48275,0.240174621,-0.126,-0.129,0.7,-0.43,-0.32,0.63,0.19,-1.31,1.61,0.66,0.06,-0.73,2.01,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0.026753086,0.15183888,CNV_LOW,1.51025813,-0.012304598,-0.033351905,-0.026722719,0.253917096,0.000231892,0.00016282,0.136843014,0.370659592,0.492497394,MSS,No,WT,WT,1.349358266,1.313865823,0.086674411,5.672425342,5.614709844,1.584962501,CNV_low,14.58333333,6.25,60.41666667,6.25,8.333333333,4.166666667,Blood_normal,d6e45feb-9d72-474c-9d5b-a0b8d6c4dc8c_gdc_realn.bam,cf748e44-e144-4034-ad2e-99d431d3be22,Tumor,deec3429-33f4-4946-a550-66acc74ee372_gdc_realn.bam,a8e8fff3-176e-4b6d-a138-ce8079f4951c,Blood_normal,1fdfd239-41aa-4c8d-8b8b-c84d4b525d67,Tumor,3c2dee34-a0e2-4ee0-9ed1-3bb9405c0070,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_TGACCA_S22_L008_R1_001.fastq.gz,46b971bf-81ed-4c18-9272-3e65823123e2,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_TGACCA_S22_L008_R2_001.fastq.gz,ae764c5a-f0ca-4a2e-b08e-ef1a65ddfe20,Tumor,36d5d1e1-8afc-4058-82ad-4893869f23a2,YES,PASS +S068,C3N-00334,No,4,14,129C,C3N-00334-02,CPT0018570003,Tumor,Yes,Ukraine,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,32.83,68,No,NA,NA,Female,"Other, specify",Uterine cavity,Multifocal,1.4,Positive,80,Positive,80,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – positive; Vimentin (Vim3B4) – positive;,Cannot be determined,1,0.005235246,0.058682364,0.120915156,0.034217712,0.062289497,0.003675535,6.69E-07,0.714983821,0.045750101,0,0.040284527,0.01546921,0,0.207054009,0,0.02143719,0,0,0.019796059,0.009842251,0.009016892,0.036097355,0.013020446,0.127467118,0.049886437,0.009914774,0,0.013023059,0,0.001940573,0.62,3171.067885,5108.003671,8279.071556,0.544691598,0.459,0.454,-0.87,0.36,-0.77,-0.18,-0.14,0.54,-0.71,-0.01,-0.02,0.36,-0.39,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,7.14E-05,0.000740447,CNV_LOW,0.623689582,-0.006951058,-0.012053628,-0.023956429,0.016728619,0.017922255,0.010002796,0.150426081,0.534767631,0.314806288,MSI-H,No,MS_indel,Frame_Shift_Del_Frame_Shift_Ins,3.691478851,3.211986209,2.218238939,8.592457037,8.06608919,6.894817763,MSI-H,16.10486891,0.74906367,62.54681648,14.98127341,3.745318352,1.872659176,Blood_normal,20e9a00b-8692-41fd-b34b-3d1028376f13_gdc_realn.bam,5c7c8278-74e6-4c50-9f43-e1977bc3bc4a,Tumor,0080c2ce-959e-42cc-8cbb-9ba2a91410e3_gdc_realn.bam,a6837fa3-b3d6-491e-91eb-e0b72fcbc5d8,Blood_normal,c11b3b83-b681-4e44-a9ac-7dd3a760752c,Tumor,6cc33674-26cb-4b7d-abc1-76081bda58ba,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_GGCTAC_S14_L006_R1_001.fastq.gz,d92fcd95-f416-4785-aca7-f8c53a3099b1,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_GGCTAC_S14_L006_R2_001.fastq.gz,18275a18-20bd-45fc-af1e-e340d86a97c6,Tumor,47b66984-bad6-411b-ace2-2bd36575d119,YES,PASS +S069,C3N-00335,No,2,8,130N,C3N-00335-05,CPT0018790003,Tumor,Yes,Ukraine,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,29.52,57,No,NA,NA,Female,"Other, specify",Uterine cavity,Multifocal,2.5,Positive,35,Positive,7,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – positive; Vimentin (Vim3B4) – negative;,Cannot be determined,None,0.009399873,0.073173287,0.133402048,0.01668522,0.060392349,0.008031966,1.04E-10,0.698915258,0.037397016,0,0.016467675,0.129747623,0,0.094326881,0.097293058,0.024431161,0,0,0.01531505,0.035347052,4.00E-04,0.042293294,0.077466078,0.174081384,0,0,0,0.036358248,0,0.009113625,0.79,5147.204936,8381.068241,13528.27318,0.70875506,-1.76,-0.609,0.99,0.99,0.15,0.24,2.15,2.39,0.33,1.4,1.96,1.42,-0.25,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.083306514,0.045518077,CNV_LOW,0.635283831,-0.003293513,-0.004209591,-0.015606792,0.002870901,0,1.68E-05,0.393045827,0.330014565,0.276939607,MSI-H,No,WT,WT,5.271130528,4.843430085,3.447198405,10.24792751,9.807354922,8.326429487,MSI-H,18.32402235,2.458100559,46.70391061,22.79329609,3.463687151,6.25698324,Blood_normal,360ce993-b06e-488c-8d6b-645b93688df0_gdc_realn.bam,30e9f0dd-467c-4332-8d66-bff36f698928,Tumor,27358361-30f1-497e-aec1-95d130c16820_gdc_realn.bam,d6c873cf-c90d-4c3b-8b69-2c51dcf49fa4,Blood_normal,90e40803-c8e8-42d5-892c-31d26341bab7,Tumor,bd8cc186-dc1e-407f-9250-4615d7e84c57,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_CTTGTA_S13_L006_R1_001.fastq.gz,ed41b710-e03a-402f-a5f5-7edd980641ae,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_CTTGTA_S13_L006_R2_001.fastq.gz,71b23a8a-c3a4-4c35-bb58-f03e9e6d8da0,Tumor,90881763-2f8c-48aa-adab-0b7534022949,YES,PASS +S070,C3N-00337,No,1,4,131,C3N-00337-04,CPT0018960003,Tumor,Yes,Ukraine,FIGO grade 3,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pNX,cM0,Staging Incomplete,Stage I,IB,0,29.07,67,No,NA,NA,Female,"Other, specify",Entire Uterine Cavity,Multifocal,1.3,Positive,80,Positive,40,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – positive; Vimentin (Vim3B4) – positive;,Cannot be determined,1,0.005483621,0.054561115,0.117235002,0.03552117,0.105357622,0.001150593,5.75E-10,0.680690877,0,0,0.043745649,0.016943114,0,0.111390552,0,0.007989276,0,0,0.02417088,0,0.011103314,0.016427891,0.004766039,0.092418353,0,0.081958621,0.003860163,0,0,0.015226148,0.43,2317.879694,3551.918217,5869.797912,0.547735947,-0.282,-1.09,0.59,0.44,0.15,0.91,-0.71,-0.47,-0.18,-0.33,-1.81,0.51,-0.18,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0.516647281,0.116898431,CNV_HIGH,4.872899162,-0.000660581,0,-0.234033494,0.458642624,0.17615102,0,0.090842904,0.682222746,0.22693435,MSS,No,WT,WT,1.483191823,1.313865823,0.389123498,5.882643049,5.614709844,3.459431619,CNV_high,20.83333333,8.333333333,52.08333333,6.25,4.166666667,8.333333333,Blood_normal,cec2f45d-c155-483f-97df-221ca574f6b9_gdc_realn.bam,7183ee6a-cb23-44bc-becd-c98704733392,Tumor,9a2dfd9e-6dd6-47a2-8e80-d48625d4e780_gdc_realn.bam,a8043bba-addf-4b7b-9349-ad547fc81f15,Blood_normal,0686705a-97fa-4c41-b9fa-15664a310849,Tumor,a09c225a-3e70-41ff-9a0e-0900c7be4f69,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_CCGTCC_S7_L005_R1_001.fastq.gz,2ed2fd9d-d69e-4924-bcac-555bfa24030e,Tumor,170818_UNC32-K00270_0050_AHL2FHBBXX_CCGTCC_S7_L005_R2_001.fastq.gz,6d9108cf-e7d8-4040-8e1d-3f707ee381c8,Tumor,e3285ecb-ca76-44c8-b642-0a9f2bdda849,YES,PASS +S071,C3N-00339,No,2,6,131,C3N-00339-02,CPT0020530003,Tumor,Yes,Ukraine,NA,under 50 %,Serous,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,21.83,45,No,NA,NA,Female,"Other, specify",Uterine cavity,Multifocal,1.3,Positive,40,Positive,60,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – focally positive; Vimentin (Vim3B4) – focally positive;,Cannot be determined,Unknown,0.008953555,0.084386617,0.20409367,0.039508302,0.065979471,0.003261892,5.75E-08,0.593816436,0,0.003299952,0.019515459,0.008406152,0,0.151782648,0,0.018158207,0,0,0,0.026200573,0,0.052651407,0.023516134,0.088148927,0.001005253,0.032505502,0,0.095529589,8.00E-04,0.0284594,0.55,3770.318861,6024.521674,9794.840535,0.851157473,-0.81,0.538,-0.43,-0.36,0.54,-0.11,0.62,2.01,-1.35,0.45,-0.51,1.02,-1.33,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.293548454,0.045922162,CNV_HIGH,3.855353468,0,-0.000582126,-0.164517995,0.098145517,0.090120448,0.044860534,0.297638094,0.472159908,0.230201998,MSS,No,WT,WT,1.121990524,1.015548827,0.207641466,5.285402219,5.087462841,2.584962501,CNV_high,12.12121212,12.12121212,48.48484848,15.15151515,6.060606061,6.060606061,Blood_normal,f9f0e294-4ac5-4fca-b75c-bdaa29f51037_gdc_realn.bam,3f967a5c-a804-4979-9bff-ccf26929a35c,Tumor,8f03933b-8c46-46b6-9b33-ca5d62d9f61d_gdc_realn.bam,0c0a86f8-c867-41de-a46c-14d6df8e69bf,Blood_normal,508fe33e-3cf2-4659-be9f-669d5d54e09d,Tumor,163c572a-c9a2-4fd6-a4e4-2471c34b02d1,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_CAGATC_S9_L003_R1_001.fastq.gz,b583347d-5091-47aa-88f4-f13b6ccdbc9b,Tumor,170818_UNC32-K00270_0051_BHLCCHBBXX_CAGATC_S9_L003_R2_001.fastq.gz,fb5ba732-fdb9-4fb1-a189-ca27dc978cfd,Tumor,cc594bce-b895-47d0-914c-a3b1980b41a6,YES,PASS +S072,C3N-00340,No,3,10,128C,C3N-00340-03,CPT0022620003,Tumor,Yes,Ukraine,NA,under 50 %,Serous,YES,Normal,pT3a (FIGO IIIA),pN1 (FIGO IIIC1),cM0,Staging Incomplete,Stage III,IIIC1,1,27,60,No,NA,NA,Female,"Other, specify",Uterine cavity,Multifocal,3.5,Negative,NA,Negative,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) –Positive; Vimentin (Vim3B4) – Negative,Cannot be determined,2,0.0067689,0.068433718,0.130744929,0.010548701,0.078487444,0.006156781,2.45E-09,0.698859525,0.010986849,0,0.010129747,0.119573197,0,0.135062253,0,0.052257959,0,0,0,0.095799524,0.006634182,0.083981574,0.065229078,0.180950468,0.017311522,0,0,0.073013728,4.00E-04,0.008671362,0.86,4660.078921,7879.766432,12539.84535,0.544317848,-1.62,-2.11,-0.18,-0.26,0.89,0.7,1.83,-0.16,0.6,1.69,1.53,-1.66,-0.91,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.409118908,0.259260859,CNV_HIGH,4.403322524,-0.047929426,-0.000856933,-0.060733953,0.045136978,0.376787468,0.000282338,0.281868662,0.403135805,0.314995532,MSS,No,WT,WT,1.277478143,1.240148892,0.086674411,5.554588852,5.491853096,1.584962501,CNV_high,22.72727273,27.27272727,31.81818182,4.545454545,9.090909091,4.545454545,Blood_normal,473ea35b-e97c-4d26-9321-84efd530f725_gdc_realn.bam,4f7981ac-194f-4927-ae66-97a7476372de,Tumor,bdc0043c-0eb0-4495-9620-7ede4bac168c_gdc_realn.bam,8c0129ea-4649-403e-9a53-2853c81782f0,Blood_normal,32560c79-2b82-4441-b1f2-fbd2838043ae,Tumor,bdd16566-8a24-4e7b-9c62-d5d9b84196eb,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_GTCCGC_S23_L006_R1_001.fastq.gz,9c6560e4-984b-4de4-b784-06e2d358ee2d,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_GTCCGC_S23_L006_R2_001.fastq.gz,b3de2a7e-ac96-42dd-bcf2-61f14df637c6,Tumor,61ad8a8e-4de3-438f-ae2f-c036d7b579a9,YES,PASS +S073,C3N-00377,No,4,14,130N,C3N-00377-02,CPT0021650003,Tumor,Yes,Ukraine,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,34,64,Yes,NA,NA,Female,"Other, specify",Uterine cavity,Multifocal,1,Positive,90,Positive,92,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – Focal positivity; Vimentin (Vim3B4) – Positive,Cannot be determined,Unknown,0.004000451,0.018259117,0.068455696,0.026465241,0.050668927,0.001646215,4.65E-10,0.830504353,0,0,0.007937663,0,0,0.09073604,0,0.019611349,0,0,0.001813999,0.008723851,0,0.087639399,0.004394117,0.028277497,0.00618781,0.023606374,0,0.109393005,0.023100596,0.1185783,0.53,1368.770354,4260.000421,5628.770775,0.828513827,-0.108,-0.888,0.03,2.52,-1.47,1.96,1.04,-0.48,-1.79,1.71,-2.22,2.28,-1.34,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.041772051,CNV_LOW,0.688823904,-0.000224265,-0.014711711,-0.01966535,0.430309377,0,0,0.168580861,0.763208662,0.068210478,MSI-H,No,WT,WT,4.103661326,3.667073084,2.456586466,9.033423002,8.566054038,7.189824559,MSI-H,13.22751323,3.968253968,65.07936508,12.43386243,3.439153439,1.851851852,Blood_normal,e41f9914-e7d0-41c2-bf1c-7cc9ef6c2a8c_gdc_realn.bam,1cecc8fa-07b8-4945-8bb9-2cd88ef2561f,Tumor,8886551e-e603-46cd-8f0e-f787821cbb00_gdc_realn.bam,3de00368-7da2-4f00-8396-3eb51f1b4b97,Blood_normal,d41328fd-e13e-41ad-affa-a32acce44ecc,Tumor,33b3fd40-ac00-4ae7-9643-e32d8fe38859,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_GTGGCC_S8_L003_R1_001.fastq.gz,927fd63f-62e5-491b-8c64-bdb58cb0881c,Tumor,171011_UNC31-K00269_0086_AHLJLCBBXX_GTGGCC_S8_L003_R2_001.fastq.gz,bc45d610-dace-4837-a41d-4a4ea3cb8b5c,Tumor,a9a39770-ecca-4f2a-b968-f23da3be8ce0,YES,PASS +S074,C3N-00379,No,3,9,129N,C3N-00379-01,CPT0015520003,Tumor,Yes,Ukraine,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,36.81,41,No,NA,NA,Female,"Other, specify",Entire uterine cavity.,Multifocal,2.5,Positive,60,Positive,80,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - positive; Vimentin - positive;,Cannot be determined,1,0.003503154,0.245873229,0.08983858,0.031302276,0.140659271,0.003490464,1.45E-08,0.485333012,9.00E-04,0,0.004338932,0.071564429,0,0.218420192,0,0.00995094,0.017933064,0,0.026913005,0.02064572,0.026199623,0.01902837,0.023567338,0.151485066,0.086513328,0.0015387,0.013040807,0,0.007938323,0,0.7,4548.865546,5698.605048,10247.47059,0.3289826,-0.055,0.863,0.2,-0.99,-0.54,-0.18,-0.21,0.51,0.62,-0.06,-0.01,-1.06,0.69,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.044645537,CNV_LOW,0.668276245,-0.013677414,-0.013714462,-0.010118216,0,0,0,0.090616832,0.305268446,0.604114722,MSS,No,WT,WT,1.037474705,0.993284573,0.086674411,5.129283017,5.044394119,1.584962501,CNV_low,28.125,25,43.75,0,0,3.125,Blood_normal,0041944a-53b2-47b2-8a4e-d50b00467f10_gdc_realn.bam,7828f203-3720-43d3-be43-c834edb7b683,Tumor,fcb00b68-150a-4231-9f7b-32cb967f8c23_gdc_realn.bam,4b47bcc5-e26c-4f9b-944e-d0e1f06ed67c,Blood_normal,546f1c4f-8040-4463-8bdf-e6b7db95345b,Tumor,3d01fbb1-f7ce-45be-960f-d4d4fcd68d73,Tumor,170823_UNC31-K00269_0076_BHLCTFBBXX_ATTCCT_S1_L001_R1_001.fastq.gz,8b3b442d-0e88-4e6c-84b0-b4eaae2be844,Tumor,170823_UNC31-K00269_0076_BHLCTFBBXX_ATTCCT_S1_L001_R2_001.fastq.gz,9c1db68b-16f9-42cd-b818-cd95a5236e11,Tumor,330c746b-4d8c-4a8b-a33f-a53d519e6091,YES,PASS +S075,C3N-00383,No,1,2,129N,C3N-00383-04,CPT0022830003,Tumor,Yes,Ukraine,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,46,61,No,NA,NA,Female,"Other, specify",Uterine cavity,Unifocal,4,Positive,70,Positive,50,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) – Positive; Vimentin (Vim3B4) – Focal positivity,Cannot be determined,1,0.005384921,0.094470153,0.097992123,0.055027196,0.132889331,0.001412001,7.50E-09,0.612824268,0,0.008617884,0.015359593,0.039137254,0,0.096250531,0,0.0026438,0,0,0,0.011322581,0.014863803,0,0,0.083600371,0.005855964,0.010619227,0.026044313,0,0.025684679,0,0.34,3237.700172,3325.590092,6563.290264,0.514479137,0.515,0.054,0.58,-0.62,-1.16,0.92,-1.74,0.66,-0.11,-1.65,0.3,-0.4,1.1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,1,1,0,0,0,0,0,0,0,0,1,0,0,0,2.31E-06,0.018125898,CNV_LOW,0.095221818,-0.001757162,0,0,0,0.004470598,0.005030412,0.054325363,0.360835808,0.584838829,MSS,No,WT,WT,1.277478143,1.258934249,0.043988012,5.554588852,5.523561956,1,CNV_low,22.22222222,4.444444444,55.55555556,6.666666667,2.222222222,8.888888889,Blood_normal,37e6dbaf-8495-467a-97d2-931a4061ec47_gdc_realn.bam,c56e7f63-aeaf-4c1e-8f3c-f17d6308709f,Tumor,6e9f2a37-b53b-4017-ae76-ac141191ea9c_gdc_realn.bam,f47e869d-e5af-4f78-a38e-af3bec29cabd,Blood_normal,ce679c8e-fc60-4adb-87c1-f1d569949992,Tumor,b48d0c57-1858-4982-9a19-2cd0475d7c36,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_GATCAG_S8_L002_R1_001.fastq.gz,d8669320-5d71-4398-b65c-26c820c08fbf,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_GATCAG_S8_L002_R2_001.fastq.gz,d98e6375-44c4-45d8-a771-293f086bc52b,Tumor,0cad6daf-f36f-43ab-90f3-f5a083fec4e9,YES,PASS +S076,C3N-00386,No,3,9,130C,C3N-00386-02,CPT0016220003,Tumor,Yes,Ukraine,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,27.31,44,No,NA,NA,Female,"Other, specify",Entire uterine cavity.,Multifocal,2.3,Positive,80,Positive,70,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - focal positivity; Vimentin - focal positivity;,Cannot be determined,2,0.003464145,0.124031449,0.106148283,0.053395146,0.075680425,0.002052767,4.21E-09,0.635227781,0.011563794,0,0.002019326,0.077080519,0,0.21779436,0,0.075026311,0,0,0,0.017937373,0,0.017185208,0.019426868,0.129435366,0.025064852,0.016131815,0.041334208,0,0,0,0.65,3739.873076,5415.732444,9155.605519,0.340749746,0.184,0.288,-0.37,-1.43,0.68,-0.58,-0.63,-0.24,0.74,-0.87,-0.11,-0.48,1.01,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0,0.089007713,CNV_LOW,1.21580133,-0.031026014,-0.03162148,-0.030961733,0,0,0,0.118997554,0.433965799,0.447036647,MSS,No,WT,WT,0.775745316,0.722601368,0.086674411,4.584962501,4.459431619,1.584962501,CNV_low,23.80952381,19.04761905,57.14285714,0,0,0,Blood_normal,d2d78e06-7a68-485f-a67e-256986fb3006_gdc_realn.bam,defc4d49-3f61-4186-8bba-95942de36e01,Tumor,86ea43f0-a9c9-47de-959c-d96c72272713_gdc_realn.bam,d7265bb5-d80b-4b5b-a2b6-2faef6b63167,Blood_normal,061f7b00-6f79-4554-b725-5778501dbccb,Tumor,160b8957-db23-4cd1-8528-c465bb3739af,Tumor,170823_UNC31-K00269_0076_BHLCTFBBXX_ATCACG_S4_L001_R1_001.fastq.gz,68aa44a5-d2a6-4ba3-ba6c-0650d6f945f4,Tumor,170823_UNC31-K00269_0076_BHLCTFBBXX_ATCACG_S4_L001_R2_001.fastq.gz,c5af6b28-5fc3-4a17-bb93-bceb731d1f80,Tumor,4a81704b-9e9a-495b-bfe5-4f6ea24ec877,YES,PASS +S077,C3N-00388,No,4,13,129N,C3N-00388-01,CPT0016940003,Tumor,Yes,Ukraine,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,20.55,59,No,NA,NA,Female,"Other, specify",Entire uterine cavity.,Multifocal,4,Positive,85,Positive,60,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 (OV-TL 12/30) - Positive; Vimentin (Vim3B4) - Negative;,Cannot be determined,1,0.004485592,0.052902816,0.105776981,0.032607874,0.061969134,0.002609858,3.06E-09,0.739647742,0,0,0.030300705,0.021893216,0,0.164865609,0,0.027823669,0.0094154,0,0.030943857,0.002314538,0.011249512,0.058283669,0.024603135,0.112311231,0,0.004934959,0,0.039742974,0,0.011317526,0.55,2390.647801,5071.823771,7462.471572,0.855693124,-0.167,-1.76,-0.08,1.32,-0.89,0.06,0.46,0.72,-0.61,1.09,-0.35,1.01,-0.62,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,1,0,0,1,0,0,0,0,0,1,0,0,0,9.62E-05,0.000609382,CNV_LOW,0.099159025,0,0,-0.001173457,0.004475428,0.006028132,0,NA,NA,NA,MSI-H,No,WT,WT,3.839223293,3.426576341,2.18915136,8.751544059,8.303780748,6.857980995,MSI-H,15.87301587,1.904761905,55.55555556,19.36507937,2.222222222,5.079365079,Blood_normal,24dbe8dc-e176-464f-94a0-006aa43bee59_gdc_realn.bam,3904884a-aa68-428b-8ed5-76e52c511f38,Tumor,2949e6ba-cb37-40b5-a7cf-09978da51025_gdc_realn.bam,168de14c-fd98-4baa-a673-d5ab0db9ad03,Blood_normal,ab9ad1e1-c9a1-44a9-b7af-d741d562a6c5,Tumor,9ef2c309-7943-42d6-9e53-6e0e7186e05a,Tumor,170823_UNC31-K00269_0076_BHLCTFBBXX_AGTTCC_S19_L005_R1_001.fastq.gz,c6980525-d030-4169-9393-0f1f73fe04a8,Tumor,170823_UNC31-K00269_0076_BHLCTFBBXX_AGTTCC_S19_L005_R2_001.fastq.gz,a989c255-f970-475b-bd15-7b7103241d2a,Tumor,22b0937f-161f-4c33-85d9-00c9c74241e3,NA,NA +S078,C3N-00389,No,1,3,131,C3N-00389-04,CPT0026270003,Tumor,Yes,Ukraine,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN0,cM0,Staging Incomplete,Stage I,IB,0,17.85,62,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Multifocal,1.5,Positive,75,Positive,70,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - positive; Vimentin - focal positivity;,Cannot be determined,1,0.012965305,0.07740866,0.127668486,0.038402581,0.065170953,0.005576804,1.44E-09,0.67280721,0,0.014679488,0.070557933,0.149854695,0,0.124816275,0.053681598,0.108819909,0.01092673,0,0,0.014971624,0,0.157369678,0.0433648,0.219421538,0.011178091,0,0.010357642,0,0,0,0.99,3323.981653,6780.561618,10104.54327,0.570927382,-0.0707,-0.604,-0.34,-1.4,-0.81,0.33,0.12,-0.6,-0.17,-0.66,0.99,0.57,-0.89,1,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,0,0,0,0,0,0,0,1,1,0,1,0.018033776,0.000785674,CNV_LOW,0.034407469,-0.001862026,0,-0.000253125,0,0.002272731,0.006610292,0.233208597,0.526925007,0.239866397,MSI-H,No,MS_indel,Frame_Shift_Del,4.44863097,3.932859217,2.919047794,9.396604781,8.851749041,7.73470962,MSI-H,13.23210412,3.036876356,59.86984816,20.60737527,1.301518438,1.952277657,Blood_normal,7306b3df-21f1-45bd-8905-0d6be9035f4d_gdc_realn.bam,7f94f3b7-bae8-4766-89d3-eb0361fd142c,Tumor,5dff9447-7da8-4573-bb38-003f96c1efa7_gdc_realn.bam,a84d1048-c1c0-418a-ac9b-efe0b9dcafbe,Blood_normal,ac7408b2-96a1-4736-8e97-f5ae263c3b21,Tumor,be158832-b452-457b-8964-8ed06a55400f,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_ATCACG_S15_L007_R1_001.fastq.gz,dd9cffde-1af6-49c4-b230-6b68529c0cab,Tumor,170828_UNC31-K00269_0077_AHLF33BBXX_ATCACG_S15_L007_R2_001.fastq.gz,0a029fc1-cddc-482f-8d17-f1aee87e877f,Tumor,0d9213fe-df70-4f56-8ceb-fef30e5f5fa4,YES,PASS +S079,C3N-00729,No,2,6,128C,"C3N-00729-02,C3N-00729-03",CPT0064930004,Tumor,No,United States,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN0,Staging Incomplete,Staging Incomplete,Stage II,IB,0,29.62,86,No,White,Not-Hispanic or Latino,Female,"Other, specify",both anterior and posterior,Multifocal,4,Positive,-1,Positive,-1,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,see comment below,Cannot be determined,4 or more,0.006626794,0.072052749,0.099153436,0.013685766,0.108277744,0.008524373,3.78E-09,0.691679134,0.00168362,0.019373833,0.033097091,0.020138707,0,0.081380422,0,0.020752246,0.006463702,0,0,0.019284594,0,0.304649896,0.007387838,0.124292888,0,0,0,0.061907521,0,0.059587641,0.76,4279.438113,6798.100266,11077.53838,0.691178947,-0.329,-1.1,0.85,0.79,-0.62,0.57,1.54,0.31,-0.53,1.96,0.73,-0.01,0.09,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.024296112,0.10927099,CNV_LOW,1.268069804,-0.000303572,-0.013557086,-0.034077111,0.266096258,0.136186586,0.005374178,0.253958448,0.556850798,0.189190754,MSS,No,WT,WT,1.732044006,1.59090564,0.389123498,6.247927513,6.044394119,3.459431619,CNV_low,13.84615385,7.692307692,56.92307692,15.38461538,3.076923077,3.076923077,Blood_normal,4c0795d8-5700-45d5-ac34-de5f2660a99d_gdc_realn.bam,2706ff8e-1101-4969-a2e3-d2bdfe201e66,Tumor,2fbd49f6-4c1b-4bb8-a92c-27ac702d593f_gdc_realn.bam,e35e206a-6a63-428d-9ee1-634c076e34f4,Blood_normal,bc11cdc1-7b13-4d28-b9c4-6ad617ca75f7,Tumor,e3322e24-bb2a-494d-b11f-619c992a284d,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_CCGTCC_S20_L006_R1_001.fastq.gz,2c0420b6-8299-46ed-8971-deab6b23eabf,Tumor,170823_UNC31-K00269_0075_AHLCW5BBXX_CCGTCC_S20_L006_R2_001.fastq.gz,f783684d-96e1-46be-a19e-686d53adf650,Tumor,205dc43a-bbe9-496e-8d14-cc23041feaf7,YES,PASS +S080,C3N-00734,No,1,1,130N,"C3N-00734-01,C3N-00734-03",CPT0026030004,Tumor,No,United States,FIGO grade 1,50 % or more,Endometrioid,YES,Normal,pT3a (FIGO IIIA),pN0,Staging Incomplete,Staging Incomplete,Stage III,IIIA,1,38.97,53,No,White,Not-Hispanic or Latino,Female,Anterior endometrium,NA,Unifocal,4,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,None,0.005026187,0.061861318,0.105775791,0.027766592,0.131855933,0.003653403,4.41E-09,0.66406077,0,0.006524058,0,0.016723849,0,0.136729657,0,0.014417241,0.001303502,0,0,0.069134349,0,0.011028416,0,0.097929766,0.009838939,0.015000539,0,0.128791658,0,0.072578025,0.58,2750.595162,5784.902177,8535.497339,0.566569828,-0.0713,-0.0363,-0.06,1.46,-0.68,-0.43,0.64,-0.1,-0.88,0.91,0.42,1.54,0.38,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,8.99E-06,0,CNV_LOW,0.033533736,0,0,-0.001532753,0.000595152,0.000266397,0,0.254109924,0.541519478,0.204370598,MSS,No,WT,WT,0.924352909,0.695276782,0.354607617,4.906890596,4.392317423,3.321928095,CNV_low,15,10,55,10,5,5,Blood_normal,d17afc43-9d34-4784-87aa-12c19595d871_gdc_realn.bam,c9c4d8b9-6c91-46e1-b6f8-d759c7f02165,Tumor,0750565e-93eb-43b6-87d3-8f84199fc1a0_gdc_realn.bam,b3fb76a3-c463-4fc1-b12c-88dbe5285071,Blood_normal,8a8cced8-56c3-41d5-aaab-2cb28481e9c1,Tumor,2a812ded-32cc-466b-9ede-be47f74903f7,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_ACAGTG_S7_L002_R1_001.fastq.gz,9faa7052-ed20-4706-97f2-c3f183a4a0bd,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_ACAGTG_S7_L002_R2_001.fastq.gz,4518b21b-b9a3-4261-b0e1-27b9f7d0e282,Tumor,0cbb0afc-eab3-4369-ba73-83ad9befb0a9,YES,PASS +S081,C3N-00743,No,3,12,128N,C3N-00743-01,CPT0062940003,Tumor,No,United States,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,No pathologic evidence of distant metastasis,Stage I,IA,0,48.46,53,No,Black or African American,Not-Hispanic or Latino,Female,"Other, specify","Involves fundus, anterior and posterior walls",Multifocal,3.5,Unknown,NA,Unknown,NA,Unknown,Unknown,Unknown,Unknown,Unknown,NA,Cannot be determined,2,0.004039392,0.168628647,0.078980272,0.035878962,0.149448996,0.000433903,6.88E-09,0.56258982,0.010998418,0,0.038080912,0.046626728,0,0.160050801,0,0.024640361,0.013355372,0,0.033115855,0.009230714,0.020732476,0.013521662,0,0.03309009,0,0.015563506,0.020993106,0,0,0,0.44,2616.128221,2870.606208,5486.734429,0.564729059,-0.378,-0.105,0.3,-0.25,-1.97,0.14,-1.99,-0.31,0.54,-1.66,-1.7,0.01,-0.42,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.005207401,0.017915723,CNV_LOW,0.585354783,-0.002837097,-0.004178351,-0.007956516,0.010595091,0.011390353,0.011912057,0.0632497,0.578781362,0.357968938,MSI-H,No,WT,WT,3.409863787,2.954052221,1.955780345,8.285402219,7.77478706,6.554588852,MSI-H,16.05504587,2.293577982,55.50458716,19.26605505,2.752293578,4.128440367,Blood_normal,5b71b4cf-7f14-42ec-bbe6-58842e3efd3f_gdc_realn.bam,7b479f2e-cccc-475d-84c6-d54ad43a5966,Tumor,fb83df64-bb73-499c-a57a-9436e26aa093_gdc_realn.bam,614a8780-9f61-476c-8d81-dbd4f18c0220,Blood_normal,d062478a-4524-4ba8-b2d6-f50395fcc112,Tumor,7a302498-b5e1-479b-898f-fd7bd524db94,Tumor,170823_UNC31-K00269_0076_BHLCTFBBXX_CTTGTA_S13_L004_R1_001.fastq.gz,a7609db0-2819-4dc0-9988-4a1323d15135,Tumor,170823_UNC31-K00269_0076_BHLCTFBBXX_CTTGTA_S13_L004_R2_001.fastq.gz,b10f3be4-53ec-4526-96d5-050e3a0eebe7,Tumor,f309b870-6a47-4af2-b619-6678eb2f07e0,YES,PASS +S082,C3N-00836,No,2,6,130C,C3N-00836-02,CPT0023810003,Tumor,Yes,Ukraine,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM1,Staging Incomplete,Stage I,IA,0,30.47,75,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Multifocal,1,Positive,40,Negative,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - positive; Vimentin - negative;,Cannot be determined,3,0.018025928,0.039861707,0.163024583,0.045724267,0.114536976,0.011478385,2.09E-09,0.607348151,0.04942716,0.016317124,0.031350984,0.63289952,0,0.003827364,0.503309554,0.159976185,0,0,0.056594181,0.054696075,0,0.175928867,0.306262844,0.443728427,0,0,0,0.034636055,0,0.031045659,2.5,5319.12579,9583.565561,14902.69135,0.680627371,-0.914,-1.34,0.37,-0.6,1.79,0.78,2.03,0.16,-0.28,1.14,1.57,-1.1,-1.42,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.30040734,0.174486818,CNV_HIGH,1.578135012,-0.003798404,-0.000574442,-0.079583915,0.043401406,0.100474431,0,0.413790787,0.24094175,0.345267463,MSS,No,WT,WT,1.450879273,1.383998466,0.168435383,5.832890014,5.727920455,2.321928095,CNV_high,21.15384615,23.07692308,34.61538462,1.923076923,9.615384615,9.615384615,Blood_normal,fa4f35a1-cb0a-4d92-8631-4f675161b355_gdc_realn.bam,fc4f4a44-123f-4d29-82e8-c155ed19910f,Tumor,08fed8ee-199e-4b11-bcee-2b3b2b320ae9_gdc_realn.bam,b3f4557b-7fb4-41e5-b5b9-44c725451295,Blood_normal,09220dab-d4b0-4d15-bb22-a222b5d0abc1,Tumor,3b118458-2f1c-42f4-9ae0-17485da8782a,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_TTAGGC_S6_L008_R1_001.fastq.gz,f19c6938-942c-47bd-b72d-79d62e8fbeb8,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_TTAGGC_S6_L008_R2_001.fastq.gz,5c51da7e-eead-4fd1-8343-c4d4ddc19458,Tumor,b2d2a0d0-15ce-4652-b46a-1ad770e5e8b2,YES,PASS +S083,C3N-00847,No,4,16,130C,C3N-00847-01,CPT0027650003,Tumor,Yes,Ukraine,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT3a (FIGO IIIA),pN0,cM0,Staging Incomplete,Stage III,IIIA,0,34.53,65,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Multifocal,4.3,Positive,95,Positive,80,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - positive; Vimentin - positive;,Cannot be determined,2,0.005454982,0.040036596,0.091207189,0.053361059,0.06545845,0.000828178,2.07E-09,0.743653544,0,0,0.010732175,0.053007557,0,0.081197741,0,0,0.056220642,0,0.008729727,0,0,0.170651046,0.007473355,0,0,0.007590874,0.032382459,0,0,0.002014424,0.43,1325.965485,2157.90896,3483.874446,0.628709017,0.624,-0.61,-0.7,0.78,-1.8,-1.02,-2.51,0.8,0.21,-2.21,-2.31,-0.3,-0.65,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018864037,0.000178777,CNV_LOW,0.372169582,-0.007844061,-0.008377274,-0.031655005,0,0,0,0.002630944,0.717091014,0.280278042,MSS,No,WT,WT,1.545723606,1.434447489,0.282995148,5.977279923,5.807354922,3,CNV_low,12.72727273,7.272727273,72.72727273,1.818181818,3.636363636,1.818181818,Blood_normal,9333c264-b25a-4ad9-8cbc-60d4d961a1e4_gdc_realn.bam,2c32b668-5200-49de-843a-bb14b3707a90,Tumor,10bc413b-8a36-4190-9e47-48750c262fa0_gdc_realn.bam,f418b6a5-909d-4f06-b3b2-da95f81bc611,Blood_normal,fbdad251-d8da-4651-9e23-ab9aa7ebdfca,Tumor,9d6fba33-07d9-4f69-80af-44adc48f100a,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_CGATGT_S6_L002_R1_001.fastq.gz,a3c73a24-ad46-4690-a782-0c9de7554f6b,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_CGATGT_S6_L002_R2_001.fastq.gz,33715f26-60b2-4c5d-994c-00faa767e9be,Tumor,6b8152cb-2fcc-49ac-8e30-562bbe846050,YES,PASS +S084,C3N-00848,No,4,15,130C,C3N-00848-02,CPT0024130003,Tumor,Yes,Ukraine,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,33.65,66,Yes,NA,NA,Female,"Other, specify",Entire uterine cavity,Multifocal,3,Positive,40,Positive,70,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK - positive; Vimentin - positive;,Cannot be determined,None,0.006741019,0.046914004,0.132741322,0.04025961,0.059487435,0.00231511,1.58E-09,0.711541498,0,0.009631275,0.078532432,0.061654733,0,0.141768576,0,0.030498309,0.0262358,0,0,0.055392899,0.009388966,0.037858222,0.011451255,0.099516218,0,0.009602334,0,0,0,0.028468981,0.6,2236.194057,4772.594927,7008.788984,0.623396118,0.628,0.41,0.39,-0.03,0.08,0.53,-0.36,-0.61,-0.53,-0.28,-0.24,0.58,0.34,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.009800931,0.195425536,CNV_LOW,2.887210768,-0.016228174,0,-0.116987117,0.215849759,0.030893769,0.000444979,0.160723734,0.594726783,0.244549483,MSS,No,WT,WT,1.691133088,1.605657252,0.245810227,6.189824559,6.06608919,2.807354922,CNV_low,16.66666667,7.575757576,60.60606061,7.575757576,1.515151515,6.060606061,Blood_normal,1d98bc15-ba29-4594-bc9d-504e70515a19_gdc_realn.bam,e562cec2-f26f-4706-9927-f13ea930d5fa,Tumor,75c83651-16d9-4099-ac1c-9ac164140aac_gdc_realn.bam,ba0c4492-c816-44ed-9ca0-6c610375514f,Blood_normal,fa7446b0-a818-4096-941d-746e73d363fa,Tumor,3a1b5ca0-555b-41e1-bd66-86c2796d69ca,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_GTGGCC_S3_L001_R1_001.fastq.gz,6e88806d-df9b-40b0-9ab9-d5f5265ef294,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_GTGGCC_S3_L001_R2_001.fastq.gz,b8f22b8f-204c-48b4-8147-5c9caf3c2f76,Tumor,087bea19-c79b-4b8a-a6fe-0f4b33a79257,YES,PASS +S085,C3N-00850,No,1,1,131,C3N-00850-02,CPT0027810003,Tumor,Yes,Ukraine,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,28.84,65,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Multifocal,1,Positive,86,Positive,95,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - positive; Vimentin - positive;,Cannot be determined,1,0.005502748,0.082280026,0.105293495,0.041651211,0.079296536,0.004117287,1.08E-09,0.681858696,0,0,0.055544593,0.191800595,0,0.098042625,0,0.05726203,0.028484946,0,0,0.048861303,0.002629565,0.095029079,0.066989651,0.174223788,2.00E-04,0,0.020947178,0,0,0,0.84,3142.491368,5804.812736,8947.304105,0.562402302,0.983,1.5,-0.33,0.29,0.07,-0.41,-0.48,1.21,0.03,-0.69,-0.23,-0.76,-0.35,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,0,1,0,0,0,3.67E-06,0.042450766,CNV_LOW,1.144517018,0,-0.031027797,-0.031470962,0.62144095,0,0,0.199052848,0.564237797,0.236709354,MSI-H,No,MS_indel,Frame_Shift_Del,3.981739572,3.572626906,2.293055185,8.903881846,8.463524373,6.988684687,MSI-H,19.31818182,1.136363636,48.01136364,18.75,7.386363636,5.397727273,Blood_normal,9872eab8-63d3-4882-877b-7b4de75bba37_gdc_realn.bam,513b27f2-8ec9-45d2-bcd4-f733bc617f3b,Tumor,850bd0cf-dd68-40b6-a6b6-83e42e76fd32_gdc_realn.bam,35036101-2e5d-4d47-bd7c-3eb638bcf6a2,Blood_normal,ac12d7d2-d6d3-454b-aa22-827c6b7a49a9,Tumor,76e8c02d-65d4-4ff0-bad5-5b0393d401f9,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_AGTTCC_S19_L005_R1_001.fastq.gz,232956d9-bea5-47c0-8fcb-bfbbb8bab7e5,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_AGTTCC_S19_L005_R2_001.fastq.gz,23941127-4227-4b4a-82ea-f76fe7062763,Tumor,aa58a384-12a8-4f6b-955e-64c110cd8a6e,YES,PASS +S086,C3N-00858,No,1,1,127N,"C3N-00858-01,C3N-00858-04",CPT0078320004,Tumor,No,Poland,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT3b (FIGO IIIB),pN0,cM0,No pathologic evidence of distant metastasis,Stage III,IIIB,1,36,65,No,NA,NA,Female,Anterior endometrium,NA,Multifocal,11,Positive,50,Positive,50,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Normal,NA,Cannot be determined,2,0.008642722,0.014995028,0.127639879,0.040554232,0.07255053,0.002238438,1.53E-10,0.733379171,0,0.013644085,0.039926845,0.055865002,0,0.058394539,0,0.010287635,0.005921685,0.004284004,0,0,0,0.099516789,0.009653509,0.094545911,0,0,0.047959996,0,0,0,0.44,1989.365377,5177.586543,7166.95192,0.813240954,-0.00667,-0.179,-0.87,0.16,-0.56,-2.47,-0.97,1.47,-1.24,-0.75,0.67,0.16,-0.69,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,4.98E-05,0.194728454,CNV_LOW,3.281137801,-0.095116164,-0.117524875,-0.116374872,0.001100237,0.000255572,0.000672214,0.121613963,0.763673461,0.114712575,MSS,No,WT,WT,1.872844004,1.691133088,0.519478029,6.442943496,6.189824559,3.906890596,CNV_low,13.88888889,6.944444444,63.88888889,6.944444444,6.944444444,1.388888889,Blood_normal,bdc38930-0dd6-4f39-a41d-56574c4b93ea_gdc_realn.bam,310f8751-c639-4b2e-86a2-5599a7e37d9d,Tumor,b93f9712-3ac1-4bf5-b4c0-a3f584dc872a_gdc_realn.bam,abf58596-7554-4be7-bd99-2b0e02a40d41,Blood_normal,c00380d4-0e17-4a1f-afdf-f94329078eaf,Tumor,4d80e3cb-84e1-405a-a6e0-3e22eef87513,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_AGTCAA_S18_L006_R1_001.fastq.gz,1a17a35c-466d-4a23-aee2-04b09c784e2a,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_AGTCAA_S18_L006_R2_001.fastq.gz,1a561b74-0af0-4d52-9288-9fa08c5d2729,Tumor,5c87b71a-c700-4731-9440-2534231a2e41,YES,PASS +S087,C3N-00866,No,2,8,127N,C3N-00866-01,CPT0063090003,Tumor,No,United States,FIGO grade 1,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,No pathologic evidence of distant metastasis,Stage I,IA,0,23.88,77,Yes,White,Not-Hispanic or Latino,Female,"Other, specify","Anterior, posterior and fundus",Multifocal,3,Unknown,NA,Unknown,NA,Unknown,Unknown,Unknown,Unknown,Unknown,NA,Cannot be determined,4 or more,0.006343461,0.020465846,0.105062707,0.043460088,0.074407637,0.003497833,4.41E-10,0.746762428,0,0.017101616,0,0.163010063,0,0.141971235,0,0.016325308,0.020834183,0,0.034585703,0.028120711,0.029366632,0,0,0.254847613,0.001366269,0.017862528,0.01460814,0,0,0,0.74,1380.859986,4333.723559,5714.583545,0.521483431,0.853,-0.197,-1.03,-1.09,-0.48,-1.63,-0.83,-0.16,-0.75,-0.57,0.08,1.68,1.3,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018712496,0.048341817,CNV_LOW,0.556900161,-0.013058781,-0.012890698,-0.017694369,0,0,0,0.097312578,0.639515552,0.26317187,MSS,No,WT,WT,1.704899366,1.620259553,0.245810227,6.209453366,6.087462841,2.807354922,CNV_low,13.43283582,7.462686567,58.20895522,11.94029851,5.970149254,2.985074627,Blood_normal,5a955d91-4992-4986-a78b-a2f80f455ea1_gdc_realn.bam,ee7f6e8b-6389-4391-9e6a-5cdc220bc39b,Tumor,6c9f01df-2bc2-405e-b94c-a673cde4f948_gdc_realn.bam,ad5ee7c0-c8bd-4cab-b438-7af8fa0c9946,Blood_normal,3cc9b549-bbac-48cc-8a82-5486203bf83d,Tumor,c825581d-0f15-4602-9895-fc171e032585,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_TTAGGC_S8_L002_R1_001.fastq.gz,99455b1b-f110-46ef-a03e-be651c28a0bd,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_TTAGGC_S8_L002_R2_001.fastq.gz,8323759d-cdc4-481c-8518-f170b5a87082,Tumor,bc1bf3bb-05d7-4eb0-8af0-8da11436dc69,YES,PASS +S088,C3N-00880,No,3,12,130N,"C3N-00880-01,C3N-00880-03,C3N-00880-04",CPT0078710004,Tumor,No,Poland,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pN0,cM0,No pathologic evidence of distant metastasis,Stage I,IA,0,27,61,No,NA,NA,Female,Anterior endometrium,NA,Unifocal,3.2,Positive,50,Positive,50,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Normal,NA,Cannot be determined,1,0.006020275,0.03431866,0.112556539,0.049057793,0.044698224,0.004422598,5.54E-09,0.748925904,0,0,0.012116224,0.03888996,0,0.080097796,0,0.011367262,0.019249438,0,0,0.034249071,0.002181305,0.046756746,0.039194685,0.184924122,0.017629382,0,0,0.006719297,6.00E-04,0.005992563,0.5,2258.605402,5297.723765,7556.329167,0.621475455,0.638,0.784,-0.46,1.38,0.82,-1.66,-0.34,-1.57,-1.28,-0.41,0.73,0.81,1.41,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,1,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018027094,0.048335778,CNV_LOW,0.923181545,-0.0229681,-0.02685752,-0.028388489,0,0,0,0.097162309,0.732064691,0.170773,MSI-H,No,WT,WT,4.648850071,4.15721395,3.043446359,9.605479518,9.09011242,7.876516947,MSI-H,17.83088235,3.125,59.00735294,15.99264706,1.654411765,2.389705882,Blood_normal,d564a1a0-e99a-4998-8fa1-df8128379f65_gdc_realn.bam,1a8134da-8b3b-4ef2-bef6-a09a7bba5847,Tumor,90388559-98b6-4014-b201-f64e4965649b_gdc_realn.bam,dbc9b510-b274-4590-b23a-606d5ae71d48,Blood_normal,a3cc4371-a3ba-4bf9-83a8-944c42d63a5d,Tumor,46d5c8ad-33ef-4601-afbd-9b24761939c4,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GTCCGC_S5_L002_R1_001.fastq.gz,f0952653-8c23-4781-a477-c2ce76f9d1b6,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GTCCGC_S5_L002_R2_001.fastq.gz,6a2bd4f3-68fc-48f2-a604-db2c5a7b665b,Tumor,a32f2c2b-53c9-4e3a-92c4-21255e14de9b,YES,PASS +S089,C3N-01001,Yes,1,2,130N,C3N-01001-03,CPT0078880003,Tumor,No,Poland,FIGO grade 2,under 50 %,Endometrioid,NO,Normal,pT2 (FIGO II),pN0,cM0,No pathologic evidence of distant metastasis,Stage II,II,0,44,72,Yes,NA,NA,Female,Posterior endometrium,NA,Unifocal,9.5,Positive,50,Positive,50,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Normal,"p169 negative, CEA positive/negative, vimentin positive, C5/6 positive",Cannot be determined,2,0.004084696,0.061835184,0.092073711,0.031092541,0.059780844,0.002658682,3.50E-07,0.748473991,0.016230354,0,5.00E-04,0.022281101,0,0.08361554,0,0.048851971,0.003613455,0,0.025937953,5.00E-04,0.014752748,0.062713266,0.010785251,0.016360624,0.026805078,0,0,0.071420892,0.020967199,0.014642587,0.44,2629.193014,4787.338006,7416.53102,0.722053168,-0.241,-0.89,2.25,1.05,-1.75,2.19,0.72,-0.37,-0.79,1.06,-0.43,0.87,-0.15,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,NA,NA,NA,NA,-0.019598685,-0.012099912,-0.010995352,0,0,0,0.114951044,0.591579306,0.29346965,MSI-H,No,MS_indel,Frame_Shift_Del,3.848555117,3.397201081,2.283912601,8.761551232,8.271463028,6.977279923,MSI-H,12.66233766,2.272727273,66.55844156,14.61038961,2.922077922,0.974025974,Blood_normal,d02e9e05-81d1-4fa8-a227-ca3cec105ba9_gdc_realn.bam,925e35ea-964c-467c-af2a-a7784b0678c5,Tumor,9b7b8a64-7bb9-4c81-ac55-726b9577429a_gdc_realn.bam,8ef06338-11c6-441b-8c8c-f3c546442f8a,Blood_normal,01c15e02-acbc-49f1-b489-5e171548b0e8,Tumor,7d46687a-97ce-4fe4-adb0-3da1045e32d4,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GTTTCG_S7_L002_R1_001.fastq.gz,f8c5ac84-6343-4a3c-9dcb-a04b0e23bb62,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GTTTCG_S7_L002_R2_001.fastq.gz,e612b542-1d0e-45ee-84b8-60d39b004a6c,Tumor,dac6ce09-1698-4b72-af83-7a89bc209f04,YES,PASS +S090,C3N-01003,No,3,9,130N,C3N-01003-01,CPT0078610003,Tumor,No,Poland,FIGO grade 1,50 % or more,Endometrioid,YES,Normal,pT3b (FIGO IIIB),pN0,cM1,pM1,Stage IV,IVB,0,31,73,Yes,NA,NA,Female,Anterior endometrium,NA,Multifocal,3,Positive,50,Positive,50,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,NA,Cannot be determined,4 or more,0.003476539,0.388840022,0.065617035,0.038687944,0.171853539,0.003535598,1.10E-07,0.327989213,0.021980571,0,0.029239852,0.039094717,0,0.125676207,0,0.025906813,0,0.004320911,0,0.038248608,0.012636839,0,0.003210075,0.157008808,0.002885581,0.01803284,0.071758177,0,0,0,0.55,4781.4706,4986.748413,9768.219013,0.259391825,1.39,0.837,-0.84,-1.01,-0.21,-0.37,-1.28,-0.73,0.84,-1.31,-0.35,-1.29,1.22,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0.200347839,0.805695672,CNV_HIGH,0.104003783,-0.001486725,0,-0.01415543,0,0.001173413,0,0.030460134,0.314292946,0.65524692,MSS,No,WT,WT,1.383998466,1.162461482,0.455772534,5.727920455,5.357552005,3.700439718,CNV_high,10,7.5,62.5,12.5,2.5,5,Blood_normal,51eb5a05-ad42-43dc-90a4-3ff7bb659a08_gdc_realn.bam,a434ccce-59e9-494a-9621-9cc732068f76,Tumor,b3f94939-b025-462f-8fff-ecbcd2a7d970_gdc_realn.bam,6e7973fa-f4a2-4c62-993e-444a64f54479,Blood_normal,f7ee25ab-e8b9-411d-8a85-30a3e162ce4b,Tumor,c3c5f8e3-f323-4657-baab-5a0af7cbc471,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_ATGTCA_S14_L006_R1_001.fastq.gz,4313d974-189f-4e5e-93c5-87adb840c560,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_ATGTCA_S14_L006_R2_001.fastq.gz,a613938d-aa43-4c67-ba0c-78c1c6c69a7b,Tumor,be14af37-382a-4a7a-a4c5-b26eabe64353,YES,PASS +S091,C3N-01211,No,3,10,127N,C3N-01211-01,CPT0075900003,Tumor,No,Ukraine,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT2 (FIGO II),pN0,cM0,Staging Incomplete,Stage II,II,1,39.2,59,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Multifocal,1.4,Positive,95,Positive,90,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - patchy positivity; Vimentin - positive;,Cannot be determined,1,0.002510216,0.094950229,0.072331793,0.025750294,0.085395952,0.002150148,6.72E-10,0.716911368,0.00875642,0,0.00339234,0.03011827,0,0.141429748,0,0.053233302,0,0,0,0.024638292,0,0.062999837,0.03294438,0.138981912,4.00E-04,0.013967784,0,0.01372593,0,0.005406991,0.53,3118.051953,4308.368448,7426.420402,0.713921113,-1.31,-2.06,0.99,0.56,-0.36,1.51,-0.54,0.83,1.39,-0.42,-1.35,1.03,-0.32,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018529704,0.036117392,CNV_LOW,0.542297565,-0.002030269,-0.016362319,-0.022462196,0.348272487,0.000405656,0,0.140145736,0.592598499,0.267255766,MSI-H,No,WT,WT,3.674088391,3.197452556,2.198912528,8.573647187,8.049848549,6.87036472,MSI-H,17.42424242,1.893939394,54.54545455,18.93939394,3.787878788,3.409090909,Blood_normal,a5ae9005-f7c0-4291-b288-df8380b29a04_gdc_realn.bam,f275ea09-8877-4159-bdee-d8781d22e740,Tumor,d29c7529-d7da-4ee6-b7c3-6af5083003af_gdc_realn.bam,37591282-8e97-4e53-82b4-13eca58214b8,Blood_normal,9c47ab95-7b62-4528-a9e5-b73bfe99dab3,Tumor,eb1be1de-2a5d-4ae4-a9bf-e62c34765a69,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GTGGCC_S8_L008_R1_001.fastq.gz,420d5f06-1231-4f16-b090-9e27da0b3c83,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GTGGCC_S8_L008_R2_001.fastq.gz,cc46aefa-d070-4531-b35b-69fef48f8fd4,Tumor,15cafcd9-5d44-4bd8-a421-7d5d7cc59aed,YES,PASS +S092,C3N-01212,No,2,6,130N,C3N-01212-03,CPT0075380003,Tumor,No,Ukraine,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT3a (FIGO IIIA),pNX,cM0,Staging Incomplete,Stage III,IIIA,1,30.48,63,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Unifocal,1.5,Positive,45,Positive,40,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - positive; Vimentin - positive;,Cannot be determined,2,0.00437853,0.057148988,0.113720547,0.023855996,0.084042172,0.003461457,7.00E-10,0.713392309,0.022408764,0,0.059210761,0.090537458,0,0.134138183,0.001489306,0.069264334,0,0,8.00E-04,0.05131453,0,0.074846217,0.034536967,0.060843228,0,0,0,0.108706228,0,0.041876884,0.75,2514.266274,5583.319319,8097.585593,0.593932274,-0.718,-0.65,1.72,1.96,-1.34,1.34,1.31,-1.14,0.34,1.52,0.02,1.06,0.43,0,1,0,0,0,1,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,4.76E-05,0.044778387,CNV_LOW,0.631934059,-0.015766433,-0.011803866,-0.009191827,0,0,0,0.199829128,0.658231952,0.14193892,MSI-H,No,MS_indel,Frame_Shift_Del,4.37949908,3.839223293,2.907188335,9.324180547,8.751544059,7.721099189,MSI-H,16.04651163,2.558139535,56.74418605,19.06976744,2.558139535,3.023255814,Blood_normal,de27373b-d06d-4246-bfbd-1fb88cc0f8fd_gdc_realn.bam,09d74eea-1860-4270-85dc-ce5bebbf6577,Tumor,26e50c35-a756-496a-a377-639add0619ee_gdc_realn.bam,9f929c14-586e-40d7-842c-7fcd83434081,Blood_normal,4bc8e960-760d-4cf1-b6b3-b52374645e4f,Tumor,aaddc8fa-2b31-41ff-8cbe-468c88441734,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GTCCGC_S5_L008_R1_001.fastq.gz,77cb79fc-c379-49ee-a61a-861b047a8d63,Tumor,170905_UNC31-K00269_0079_AHLCF7BBXX_GTCCGC_S5_L008_R2_001.fastq.gz,70834e25-c655-4715-a7f8-57741576d457,Tumor,ff1a87b5-026f-4592-9e90-6a156e07dca5,YES,PASS +S093,C3N-01217,No,2,7,130N,C3N-01217-01,CPT0076500003,Tumor,No,Ukraine,FIGO grade 1,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pNX,cM0,Staging Incomplete,Stage I,IB,0,36.2,58,No,NA,NA,Female,"Other, specify",Endometrium,Multifocal,0.8,Positive,80,Positive,85,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - positive; Vimentin - positive;,Cannot be determined,None,0.005318682,0.104628581,0.090943407,0.063668402,0.084442983,0.002557199,1.81E-09,0.648440744,0,0,0.049541359,0.038721394,0,0.113462274,0,0,0.012461263,0,0,0.019183604,0.039610944,0,0.004096005,0.193189949,0,0.009557828,0.026629608,0.00227769,0.001268082,0,0.51,4181.890175,4241.500932,8423.391107,0.416725667,0.736,1.06,-1.37,-1.21,-0.49,-0.96,-1.1,-1.01,0.05,-1.03,0.17,-0.56,-0.5,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018036765,7.33E-05,CNV_LOW,0.030015236,0,-0.000473355,0,0.000333665,0.00034245,0.002322995,0.046631214,0.337676312,0.615692473,MSS,No,WT,WT,1.142367912,0.947697998,0.354607617,5.321928095,4.95419631,3.321928095,CNV_low,16.66666667,3.333333333,60,13.33333333,0,6.666666667,Blood_normal,b198fef8-363e-4231-97b0-2b31b0f928fa_gdc_realn.bam,c4fd71e5-acf9-4b52-a1bb-e1f757042066,Tumor,73ad916a-e94f-45f8-9ca7-3de307f3a46c_gdc_realn.bam,c549bd7c-0935-4276-a507-7b7fc9b54a60,Blood_normal,1a91f81d-f6e4-4ce3-9d38-0ab56f84767b,Tumor,9a74ea27-cda9-4e07-a710-db1b432ecf4e,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_GCCAAT_S22_L006_R1_001.fastq.gz,e60a5351-d5bd-4e4c-b9d2-64fcdca999b1,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_GCCAAT_S22_L006_R2_001.fastq.gz,03100748-7dc8-4f11-a46f-9153d3769556,Tumor,df38c029-6aec-4541-8a56-77c59e233226,YES,PASS +S094,C3N-01219,No,3,12,128C,C3N-01219-03,CPT0076160003,Tumor,No,Ukraine,FIGO grade 3,under 50 %,Endometrioid,YES,Normal,pT3a (FIGO IIIA),pN0,cM0,Staging Incomplete,Stage III,IIIA,0,26.14,58,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Unifocal,5,Positive,90,Positive,80,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - patchy positive; Vimentin - negative;,Cannot be determined,1,0.007294917,0.035342991,0.160684601,0.052033662,0.076176778,0.009797105,2.82E-08,0.658669918,0,0.009145218,0.014336444,0.264904483,0,0.173192267,0.031665751,0.104941128,0,0.265176591,0,0.036010774,0,0.181109898,0.20547773,0.307954382,0.021208229,0,0.014877105,0,0,0,1.63,3607.302476,8247.18979,11854.49227,0.72200942,0.583,-0.458,-0.54,-0.03,-0.61,-0.24,0.26,-0.67,-0.19,-0.38,1.17,0.5,-0.62,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,1,1,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018047975,0.021422303,CNV_LOW,0.39358965,-0.003782297,-0.002169021,-0.00619722,0,0,0,0.312899462,0.57498839,0.112112148,MSI-H,No,MS_indel,Frame_Shift_Del,4.42387369,3.915204152,2.883172881,9.370687407,8.832890014,7.693486957,MSI-H,14.28571429,3.516483516,58.68131868,18.46153846,3.296703297,1.758241758,Blood_normal,d4c44cff-6bfd-46e0-a542-426345f7afff_gdc_realn.bam,6b91773f-2a59-4a80-ac8c-f7bd3a92755d,Tumor,14e343cd-1aff-4e8b-8bd8-7c4813ec2405_gdc_realn.bam,8f2fb70a-9111-4662-b07b-937b3880b9f2,Blood_normal,130cc23b-3c75-406e-b2e3-6c762c8dcfc7,Tumor,8fc2d44a-4784-476b-83f4-d860c3e7ef4b,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_ACAGTG_S23_L006_R1_001.fastq.gz,e20212d2-8826-470e-8ea9-fd482194e637,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_ACAGTG_S23_L006_R2_001.fastq.gz,4411b385-dfc9-42a7-b200-a2ef23950c1e,Tumor,13797ccd-aaba-4224-ac1c-c5aff52d21fe,YES,PASS +S095,C3N-01267,No,3,10,129C,C3N-01267-03,CPT0027970003,Tumor,No,Ukraine,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT1b (FIGO IB),pN1 (FIGO IIIC1),cM0,Staging Incomplete,Stage III,IIIC1,1,30.85,57,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Multifocal,1.2,Positive,80,Positive,90,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - positive; Vimentin - positive;,Cannot be determined,2,0.003797846,0.077860922,0.091939368,0.035186068,0.178905676,0.002576266,1.90E-08,0.609733834,0,0.0019259,0.012271592,0.034484496,0,0.208514252,0,0,0,0,0.011965047,0.02334588,0.006748859,0,0.007875625,0.162633253,0,0.00602792,0.036807022,0,0.007400155,0,0.52,4265.396681,4751.649418,9017.046099,0.334574905,-0.248,-0.48,-0.11,-0.56,-1.1,-0.32,-1.16,-0.68,1.33,-0.91,-0.97,-0.82,0.55,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.018025661,0.251575936,CNV_LOW,2.141732857,0,-0.079315575,-0.081189645,0.410300448,0,0,0.096244666,0.359083985,0.544671348,MSS,No,WT,WT,0.993284573,0.970671335,0.043988012,5.044394119,5,1,CNV_low,9.677419355,12.90322581,51.61290323,16.12903226,0,9.677419355,Blood_normal,ef8eadff-62be-4e36-a2d3-9d4a618b2ff2_gdc_realn.bam,1042e2b7-3bc3-4b8d-8437-bd7bfdf5d5d4,Tumor,441ce217-806a-46cc-84fd-6391b0ba2d82_gdc_realn.bam,fc5809c5-56de-45d7-8805-0ef944f75972,Blood_normal,a532762d-a05a-4be3-911a-21a9c44c1c5c,Tumor,6a16e63f-e0cb-4ff2-bc69-f077232f3b2c,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_ATGTCA_S18_L005_R1_001.fastq.gz,63431135-a82e-4a29-a17d-70ca5b7def70,Tumor,170912_UNC31-K00269_0081_AHL3YKBBXX_ATGTCA_S18_L005_R2_001.fastq.gz,a09574f4-c3e1-428c-a8a0-412950a3872a,Tumor,377ea8b8-844d-4667-be85-63165095a652,YES,PASS +S096,C3N-01346,No,4,13,127N,"C3N-01346-03,C3N-01346-04",CPT0116550004,Tumor,No,Poland,NA,50 % or more,Serous,YES,Normal,pT1b (FIGO IB),pN2 (FIGO IIIC2),cM0,No pathologic evidence of distant metastasis,Stage III,IIIC2,1,34,63,NA,NA,NA,Female,Anterior endometrium,NA,Unifocal,5.5,Positive,5,Positive,10,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,"Ki67 positive 90%, Vimentin positive - 5%, SMA negative, CD10 - negative, miogenine - negative, desmine - negative, S-100 - negative",Cannot be determined,1,0.006765475,0.12302872,0.108917746,0.031112939,0.085797165,0.00826782,7.83E-09,0.636110127,0.003670969,0,0.029677669,0.085321157,0,0.14099011,0.002679818,0.081837455,0.025438194,0,0,0.029795527,0.015829072,0.101667828,0.088930214,0.26555035,0.019213128,0,0.012959135,0,0.016439373,0,0.92,4617.267994,7726.246196,12343.51419,0.832173788,-0.246,-3.06,-0.44,0.62,1.02,-1.4,-0.05,-0.34,0.31,-0.9,-0.1,0.04,-1.36,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0.273023239,0.073642226,CNV_HIGH,3.902728214,-0.001980205,-0.001974315,-0.31732797,0.092649243,0.426536847,0.011365024,NA,NA,NA,MSS,No,WT,WT,1.258934249,1.162461482,0.207641466,5.523561956,5.357552005,2.584962501,CNV_high,10,25,32.5,12.5,10,10,Blood_normal,3db17e2b-7fc3-4dc1-9fa9-e0859db32a3e_wxs_gdc_realn.bam,1a0e6a0f-57d5-4378-80a4-d124eb1a8779,Tumor,c045de53-714c-4f81-8f6a-333f80db7d72_wxs_gdc_realn.bam,57d796cc-0636-4958-937c-4f8bdb46ebbe,Blood_normal,0149a1bf-30e0-41c3-994d-70bb82818c4d,Tumor,1a0c3a89-4547-4e37-aede-265ae25de36f,Tumor,180502_UNC32-K00270_0094_BHTVLMBBXX_CAGATC_S11_L003_R1_001.fastq.gz,e471cc71-0f0b-421b-a1fb-40136d957698,Tumor,180502_UNC32-K00270_0094_BHTVLMBBXX_CAGATC_S11_L003_R2_001.fastq.gz,05f8cd15-4e8b-4bc0-abb9-86024f30587e,Tumor,b3fa7771-1083-4451-a72f-648e12f99fb6,NA,NA +S097,C3N-01349,No,4,14,127N,C3N-01349-02,CPT0116630003,Tumor,No,Poland,NA,50 % or more,Serous,YES,Normal,pT1b (FIGO IB),pN0,cM0,No pathologic evidence of distant metastasis,Stage I,IB,1,31,77,Yes,NA,NA,Female,Anterior endometrium,NA,Multifocal,5,Negative,NA,Negative,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Overexpression,NA,Cannot be determined,4 or more,0.009739342,0.037214567,0.111071052,0.026449078,0.084138822,0.010901218,8.09E-10,0.720485921,0,0.040723911,0.026971786,0.063511306,0,0.031092652,0,0.036809347,0.017676251,0.004317008,0,0.066840911,0,0.207247911,0.052855743,0.176413766,0,0.029581456,0,0.01149725,0,0.044460701,0.81,3784.055606,7310.646586,11094.70219,0.740758872,-0.808,-2.1,-0.03,1.41,1.98,-0.27,1.42,-0.4,-0.34,1.38,1.91,-1.52,-0.64,0,0,0,0,1,1,1,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,0,0,0,0.199043404,0.126832043,CNV_HIGH,3.377673268,-0.016427767,-0.004073222,-0.028878096,0.151209284,0.176426135,0.001457121,NA,NA,NA,MSS,No,WT,WT,2.066555769,2.023260846,0.168435383,6.700439718,6.64385619,2.321928095,CNV_high,13.13131313,14.14141414,48.48484848,9.090909091,8.080808081,7.070707071,Blood_normal,567a10ad-cdde-4eb0-8466-fc347bebfc3d_wxs_gdc_realn.bam,529af22f-6b99-4f52-8adf-7d13636e3990,Tumor,22644f97-481a-4e62-a318-5f5e77b80855_wxs_gdc_realn.bam,c94b89bc-2589-4dbc-b42c-53dbd252d63b,Blood_normal,6207248b-6334-4d87-a3fe-328bd55629f8,Tumor,fc1377b1-042b-4c9d-91a4-03028f920461,Tumor,180502_UNC32-K00270_0094_BHTVLMBBXX_ACTTGA_S10_L003_R1_001.fastq.gz,61da9b88-7482-4b7a-8e66-275ecf12ceaf,Tumor,180502_UNC32-K00270_0094_BHTVLMBBXX_ACTTGA_S10_L003_R2_001.fastq.gz,c23d4640-ab47-475d-9805-92cabdd16f22,Tumor,de22a6aa-fd4b-49bf-9177-5839c2db4c1c,NA,NA +S098,C3N-01510,No,4,14,131,C3N-01510-02,CPT0079650003,Tumor,No,United States,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT2 (FIGO II),pNX,Staging Incomplete,Staging Incomplete,Stage II,II,1,40.72,53,Yes,White,Not-Hispanic or Latino,Female,"Other, specify",Bulky tumor involving both anterior and posterior walls,Multifocal,8.5,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,None,0.004837211,0.024165291,0.089824854,0.043054277,0.06940191,0.002293855,3.05E-09,0.766422598,0,0,0.019304946,0.073887376,0,0.074485955,0,0.045953357,0,0,0.003062666,0.002659192,0.003415035,0.01575249,0.00889596,0.137475272,0,0.012682978,0,0.037907652,0.002005813,0.022511308,0.46,1445.656243,4373.982627,5819.638871,0.518388581,-0.0498,-1.21,0.47,3.42,-1.16,1.15,0.59,-0.53,-0.15,1.06,-0.93,1.48,0.63,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,1,0,0,0,0,1,0,0,0,0,0,0,0,0,1,1,0,1,3.64E-06,0.000132588,CNV_LOW,0.332383257,-0.009007688,-0.00690175,-0.00851741,0,0.001213689,0,0.092486411,0.753031126,0.154482463,MSS,No,WT,WT,3.341007532,3.2871191,0.455772534,8.209453366,8.14974712,3.700439718,CNV_low,2.473498233,1.413427562,94.34628975,0.706713781,0.706713781,0.35335689,Blood_normal,f8e5df28-e72a-43d1-867f-2774935b9d1b_gdc_realn.bam,1b6a1313-bd3c-44c1-a4e6-379bee72ac96,Tumor,6071b625-57fb-4113-9926-83e265a78d28_gdc_realn.bam,b9b9dea4-2021-4f06-8697-048fa9d1baa0,Blood_normal,5ef81d6b-2d4a-4ed8-960b-eea9cf8c3598,Tumor,f8c5708f-f692-4381-92ea-4dcf5a970d14,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_AGTCAA_S15_L004_R1_001.fastq.gz,9c598e26-c32b-4405-af2a-c560941fb81a,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_AGTCAA_S15_L004_R2_001.fastq.gz,086afb47-3e44-4075-900f-c9efeb622959,Tumor,d638a8d7-7f93-4497-be48-921ede96da0b,YES,PASS +S099,C3N-01520,No,3,12,129N,C3N-01520-01,CPT0076860003,Tumor,No,Ukraine,FIGO grade 2,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,29.37,69,No,NA,NA,Female,"Other, specify",Endometrium,Multifocal,1,Positive,60,Positive,65,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - positive; Vimentin - patchy positive;,Cannot be determined,2,0.007382878,0.035083294,0.133624962,0.04943904,0.077794978,0.003529352,9.11E-08,0.693145404,0,0,0.058648319,0.066290344,0,0.098306727,0.065220541,0.063741986,0,0.070019705,0,0.027449986,0,0.063996724,0.059493274,0.158603661,0,0,0,0.049773167,0,0.008455565,0.79,2659.994806,6104.870732,8764.865538,0.634661788,-0.155,0.856,0.03,0.6,-0.9,-0.2,0.27,1.26,-1.17,-0.43,0.29,0.35,0.57,0,0,0,0,0,0,0,1,0,0,1,1,0,0,1,0,1,0,1,0,1,0,0,1,0,0,0,0,0,0,1,1,1,0,1,1,0,0.075011161,CNV_LOW,0.91735067,-0.019652702,-0.021330753,-0.018841793,0,0,0,0.200823898,0.714476676,0.084699426,MSI-H,No,WT,Frame_Shift_Ins_Nonsense_Mutation,6.863169791,6.7573255,3.207157908,11.86457308,11.75780667,8.060695932,MSI-H,23.22357019,2.253032929,53.43731947,16.926632,1.964182553,2.195262854,Blood_normal,22d8111e-ed85-442f-a8ff-2bc44792e155_gdc_realn.bam,76483f05-7126-45ca-ada5-39b1d8af487c,Tumor,7dea6331-0e16-40e5-b908-e9b403f848f6_gdc_realn.bam,03c88b74-e1bd-4a90-ac3d-2fbd9bdfaa2b,Blood_normal,021c018b-52e5-4d30-86e0-a0758b6eb859,Tumor,d4f7f077-eadb-471d-8ab2-dcc8035aa087,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_GCCAAT_S2_L007_R1_001.fastq.gz,a43b1b15-3b59-4e11-b589-8d89b7e63209,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_GCCAAT_S2_L007_R2_001.fastq.gz,b3135f8c-5c50-41a8-ae39-a427c93a993f,NA,NA,YES,PASS +S100,C3N-01521,No,4,14,128C,C3N-01521-01,CPT0076680003,Tumor,No,Ukraine,FIGO grade 3,under 50 %,Endometrioid,YES,Normal,pT1a (FIGO IA),pNX,cM0,Staging Incomplete,Stage I,IA,0,29.4,75,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Unifocal,4.2,Positive,60,Positive,80,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - negative; Vimentin - patchy positive;,Cannot be determined,2,0.004994598,0.035242686,0.085099802,0.031691155,0.098499307,0.005015088,2.82E-07,0.739457081,0.01763236,0,0.007080589,0.06592389,0,0.071179987,0,0,0.02562487,0,0.034393768,0.008318946,0.011821109,0.063638898,0.042764415,0.095607114,0,0.043358278,0.083143647,0,0,0.019512128,0.59,2795.977059,5789.410018,8585.387077,0.75823875,-0.37,-0.451,-0.18,0.87,2.7,-0.82,0,-0.07,-1.24,-0.11,0.29,-0.04,-0.73,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.289753048,0.329561071,CNV_HIGH,5.501272687,0,0,-0.076203323,0.260744145,0.242258634,0.01483176,0.248159781,0.544443077,0.207397142,MSS,No,WT,WT,0.993284573,0.947697998,0.086674411,5.044394119,4.95419631,1.584962501,CNV_high,6.666666667,16.66666667,50,13.33333333,6.666666667,6.666666667,Blood_normal,ac16a9c0-e9f4-4bdf-ba76-78d9438f0b10_gdc_realn.bam,c670d6d3-0ad3-481c-9336-20d351ffc7dc,Tumor,ff6a7b50-074e-4229-a5b1-282d7e4c9208_gdc_realn.bam,1c684370-d3c3-4bf9-82df-6cd1a2b107e2,Blood_normal,de536564-ee0b-471a-a157-203f5b67fb71,Tumor,2c1c0ba9-0049-4e08-adbd-173e7d68433d,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_ACAGTG_S3_L007_R1_001.fastq.gz,0acc093f-71f7-4f80-a9b2-20e017cbd7e4,Tumor,170830_UNC31-K00269_0078_AHLCVMBBXX_ACAGTG_S3_L007_R2_001.fastq.gz,1b05444d-acbf-4aa3-9981-0803c58db907,Tumor,740061a5-ffd5-4640-b888-aae0fae0779e,YES,PASS +S101,C3N-01537,No,4,13,129C,C3N-01537-01,CPT0097010003,Tumor,No,Ukraine,FIGO grade 2,50 % or more,Endometrioid,YES,Normal,pT2 (FIGO II),pN0,cM0,Staging Incomplete,Stage II,II,0,35.42,74,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Unifocal,1.5,Positive,80,Positive,20,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cytokeratin 7 - positive; Vimentin - negative;,Cannot be determined,1,0.014872008,0.036505622,0.194267542,0.033524424,0.064904537,0.010912287,1.49E-09,0.645013579,0.045215956,0.00180072,0.024315518,0.143705494,0,0.239386292,0.049980042,0.139580503,0,0.029759765,0,0.047962053,0,0.166271953,0.207608597,0.390061502,0,0,0.004351604,0,0,0,1.49,4336.999577,9113.414303,13450.41388,0.769073842,-0.318,-1.64,-0.61,-0.97,2.09,-0.24,1.33,-0.51,-0.88,0.53,1.81,-1.75,0.64,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0.171819961,0.085911472,CNV_HIGH,1.556572742,-0.021722017,0,-0.027478768,0.141450915,0.083155192,0.001175305,0.335899561,0.330951988,0.333148452,MSS,No,WT,WT,1.05907234,0.924352909,0.245810227,5.169925001,4.906890596,2.807354922,CNV_high,17.24137931,13.79310345,58.62068966,3.448275862,3.448275862,3.448275862,Blood_normal,ef01edb4-ba7c-427e-a2b0-d5099f8d06fb_wxs_gdc_realn.bam,07b497aa-3dd9-433a-b3fc-1d6ff9c23806,Tumor,af300af0-16e5-424e-8f44-acb85517ac35_wxs_gdc_realn.bam,8896b39a-df49-48b1-97f6-2573ecef6b08,Blood_normal,809337b5-5049-4bb0-942f-b85a59d52743,Tumor,1c4ad51e-2c49-44ce-855e-8601191e51f1,Tumor,171107_UNC32-K00270_0063_BHLNTCBBXX_CAGATC_S60_L007_R1_001.fastq.gz,c00f784d-3143-4e88-b652-40a42aa38f53,Tumor,171107_UNC32-K00270_0063_BHLNTCBBXX_CAGATC_S60_L007_R2_001.fastq.gz,53445ea6-98ca-4134-a8bb-cd64497935a7,Tumor,5152f497-62fb-48b5-bdbd-37053a905ff5,YES,PASS +S102,C3N-01802,No,4,16,128C,C3N-01802-01,CPT0080030003,Tumor,No,United States,NA,under 50 %,Serous,YES,Normal,pT2 (FIGO II),pN0,Staging Incomplete,Staging Incomplete,Stage II,II,1,24.32,85,Yes,Black or African American,Not-Hispanic or Latino,Female,"Other, specify",entire uterine cavity,Unifocal,3.8,Cannot be determined,NA,Cannot be determined,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,NA,Cannot be determined,1,0.009022295,0.056699664,0.22202567,5.12E-08,0.069009999,0.008491865,4.80E-09,0.63475045,0.003029268,0,0.038323966,0.24395747,0,0.125632435,0.275833718,0,0,0,0.065210688,0,0.023056066,0.056808071,0.099728201,0.145488511,0.00549566,0,0,0.058770763,0.021394706,0.047270477,1.21,4822.4358,8568.337599,13390.7734,0.599249078,-0.403,-2.9,2.45,0.88,0.41,1.7,3.31,-0.44,-0.1,2.82,2.03,1.53,-0.99,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.188981339,0.111791982,CNV_HIGH,3.07327003,-0.068690488,-0.000314798,-0.246613392,0.118123338,0.163937849,0,0.365215471,0.443528669,0.19125586,MSS,No,WT,WT,1.576001633,1.417826394,0.389123498,6.022367813,5.781359714,3.459431619,CNV_high,24.07407407,5.555555556,57.40740741,5.555555556,1.851851852,5.555555556,Blood_normal,f5ae7b0e-9213-4424-a10e-7f1383d33b5b_gdc_realn.bam,b16d3cc5-43af-4b25-ab64-b262492b6e42,Tumor,ef72c57f-f998-4e9a-a563-b5969a93bcd8_gdc_realn.bam,00527d6d-5b39-4a0e-a36a-30a88d5601ae,Blood_normal,68ed2c5e-6ac7-4305-b273-d1c649e89954,Tumor,95d70287-457f-4f51-80b5-25d771f72a64,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_CCGTCC_S16_L004_R1_001.fastq.gz,06944ccc-05d4-42d9-917f-3e3e86355149,Tumor,170906_UNC32-K00270_0058_BHLJ7FBBXX_CCGTCC_S16_L004_R2_001.fastq.gz,6820bed8-165e-49af-bfeb-3cd127060651,Tumor,2533a15d-a790-4a3f-868a-fd30f6329dc8,YES,PASS +S103,C3N-01825,No,3,10,129N,C3N-01825-01,CPT0097710003,Tumor,No,Ukraine,NA,under 50 %,Serous,YES,Normal,pT1a (FIGO IA),pN0,cM0,Staging Incomplete,Stage I,IA,0,34.06,70,No,NA,NA,Female,"Other, specify",Entire uterine cavity,Unifocal,5,Negative,NA,Negative,NA,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,Cannot be determined,CK7 - positive; Vimentine - negative;,Cannot be determined,Unknown,0.004767503,0.237164751,0.089595072,0.028463459,0.184282336,0.004165019,7.00E-09,0.451561854,0.058010582,0,0.064580904,0.030642108,0,0.187681071,0,0.05056075,0,6.00E-04,0,0.003258252,0,0.430658443,0.064693237,0.22904602,0,0,0.042631692,0.005492839,0,0.022128812,1.19,5933.572259,6081.794155,12015.36641,0.465887297,-0.867,-1.42,-0.51,-0.72,0.28,-0.62,0.19,-1,1.75,0.63,0.31,-1.65,-0.35,0,0,0,0,1,1,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,1,0,0,0,0.156151631,0.131671202,CNV_HIGH,0.771704727,0,-0.015492594,-0.004088097,0.025331244,0.075747549,0,0.250298316,0.16252204,0.587179644,MSS,No,WT,WT,1.05907234,1.037474705,0.043988012,5.169925001,5.129283017,1,CNV_high,23.52941176,5.882352941,58.82352941,11.76470588,0,0,Blood_normal,e85c33bd-3b8d-4bad-9735-e48f81491019_wxs_gdc_realn.bam,bb985682-1aad-4aa0-acd4-039b2e5f2b49,Tumor,3ec666f3-df1c-438d-bcc1-555e4c7db92b_wxs_gdc_realn.bam,e079441f-c166-44ee-b53b-33a6f6fcff85,Blood_normal,522582a7-24d6-4b9a-9e6a-5116e3ca5c72,Tumor,eb0e4fbc-5442-43f8-ae0e-4d8d6cb67f59,Tumor,171107_UNC32-K00270_0063_BHLNTCBBXX_TAGCTT_S56_L006_R1_001.fastq.gz,fb6e7290-6e05-40fd-b122-340633db8e34,Tumor,171107_UNC32-K00270_0063_BHLNTCBBXX_TAGCTT_S56_L006_R2_001.fastq.gz,ee34816a-0060-45f6-9813-334207970349,Tumor,4190843f-c561-452f-bffb-f78e62131558,YES,PASS +S104,C3N-01825_replication,Yes,4,16,131,C3N-01825-03,CPT0097730003,Tumor,No,Ukraine,NA,under 50 %,Serous,YES,Normal,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.449,-1.35,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S105,C3L-00006,No,2,5,128C,C3L-00006-06,CPT0001470001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.134372832,0.393,-0.0215,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180313_UNC32-K00270_0085_BHT2MGBBXX_CCGTCC_S39_L007_R1_001.fastq.gz,caea5e0c-f3be-4db4-8837-c3f5d89ac4a6,Adjacent_normal,180313_UNC32-K00270_0085_BHT2MGBBXX_CCGTCC_S39_L007_R2_001.fastq.gz,d5b2b761-e82a-4829-8aab-a78d87cde2a1,Adjacent_normal,3639fff9-4be4-4787-8565-24da63af1595,NA,NA +S106,C3L-00361,No,1,2,127N,C3L-00361-06,CPT0002450001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.060639595,0.39,1.18,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_TTAGGC_S5_L002_R1_001.fastq.gz,2bb0bf8f-ed23-4cc6-aaa6-f36f1d0811ab,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_TTAGGC_S5_L002_R2_001.fastq.gz,6c30343e-37cb-40c2-898e-44c3125b5afd,Adjacent_normal,30f27a74-757b-4ac8-a2e8-51c36b79c09f,NA,NA +S107,C3L-00586,No,2,6,129N,C3L-00586-06,CPT0023640001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.021185693,0.138,0.268,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_GCCAAT_S7_L002_R1_001.fastq.gz,52d135b5-6065-44c4-abc4-8245ce9694dd,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_GCCAAT_S7_L002_R2_001.fastq.gz,9509bda6-905c-4583-b31a-debc0d5afc82,Adjacent_normal,736ecc5f-7d9b-4179-bb05-42a48e26d29d,NA,NA +S108,C3L-00601,No,2,6,127N,C3L-00601-06,CPT0007660001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.097223501,1.48,0.096,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_ACAGTG_S1_L002_R1_001.fastq.gz,15a20d32-beec-4388-9408-480db8a1ae5c,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_ACAGTG_S1_L002_R2_001.fastq.gz,0a6f5a3c-53aa-41bc-8c68-7292e1e6b059,Adjacent_normal,a370a813-54eb-4977-964c-8da43f070efc,NA,NA +S109,C3L-00769,No,2,5,129C,C3L-00769-02,CPT0026540001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.613,0.95,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S110,C3L-00930,No,2,7,129C,C3L-00930-02,CPT0027020001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.672,-0.879,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S111,C3L-00932,No,2,8,128N,C3L-00932-02,CPT0027130001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.163867753,0.736,1.19,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_ACAGTG_S1_L001_R1_001.fastq.gz,db54b077-a421-4528-9067-5fdc52ee5366,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_ACAGTG_S1_L001_R2_001.fastq.gz,1d2625d3-cb72-4722-aee4-b522a30139e0,Adjacent_normal,b5b182e1-0ebf-461b-a8d2-82877ff266a8,NA,NA +S112,C3L-00947,No,1,1,129C,C3L-00947-02,CPT0027430001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.13,0.787,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S113,C3L-00963,No,2,8,129N,C3L-00963-02,CPT0016530001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.05,0.478,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S114,C3L-01246,No,2,7,127C,C3L-01246-02,CPT0080990001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.961,1.14,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S115,C3L-01249,No,1,2,128N,C3L-01249-02,CPT0080890001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.127,0.481,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S116,C3L-01252,No,1,1,128N,C3L-01252-02,CPT0080620001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.0702,0.19,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S117,C3L-01256,No,1,3,129N,C3L-01256-02,CPT0073460001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.39,1.18,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S118,C3L-01257,No,2,7,128C,C3L-01257-02,CPT0073530001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.05,1.31,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S119,C3L-01282,No,1,4,128N,C3L-01282-06,CPT0077660001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.182616031,1.12,0.835,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_CGATGT_S10_L003_R1_001.fastq.gz,b75aa815-18fc-4f67-8bd8-e80d70bf58d7,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_CGATGT_S10_L003_R2_001.fastq.gz,6c986f25-4352-4b8d-9f37-2de28762849a,Adjacent_normal,0041d301-1307-4d69-80ba-66be7f48afb6,NA,NA +S120,C3L-01304,No,1,4,129N,C3L-01304-06,CPT0064240001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.149158878,0.197,0.867,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_CAGATC_S3_L001_R1_001.fastq.gz,fb12c9f3-e9e4-4234-b1ea-b652ea9e064d,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_CAGATC_S3_L001_R2_001.fastq.gz,9272b657-6b27-4628-adff-898271064f68,Adjacent_normal,40da7b55-0225-4641-ac4a-27630855d845,NA,NA +S121,C3L-01307,No,1,4,127N,C3L-01307-06,CPT0064320001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.086623051,0.622,0.975,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_ACTTGA_S2_L001_R1_001.fastq.gz,636ef258-acbd-443f-99c4-8966ebf303af,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_ACTTGA_S2_L001_R2_001.fastq.gz,8b68efdb-23b2-4936-8426-1d26933f64a5,Adjacent_normal,44d9a77d-4a1e-4130-9bc2-4d82107db6d0,NA,NA +S122,C3L-01311,No,1,3,128C,C3L-01311-06,CPT0077780001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.105167881,0.815,1.69,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_TGACCA_S6_L002_R1_001.fastq.gz,46a9c137-590c-40f8-83a9-848a8d0437a5,Adjacent_normal,180109_UNC31-K00269_0107_AHNHY2BBXX_TGACCA_S6_L002_R2_001.fastq.gz,7bcd0306-0e63-4202-88b1-1ed2497e3547,Adjacent_normal,9e327c15-9d40-4c45-8375-748e81c21667,NA,NA +S123,C3L-01744,No,1,3,127C,C3L-01744-02,CPT0093290000,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.155,0.489,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S124,C3N-00333,No,2,5,127C,C3N-00333-07,CPT0011020003,Adjacent_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.080335244,0.198,-0.236,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,171215_UNC32-K00270_0073_BHN3NFBBXX_CCGTCC_S5_L002_R1_001.fastq.gz,3b0cb9d5-e735-43db-81bc-dd41c5404e88,Adjacent_normal,171215_UNC32-K00270_0073_BHN3NFBBXX_CCGTCC_S5_L002_R2_001.fastq.gz,2e65e11f-f0c6-43e1-a97f-42beb6bcf2e9,Adjacent_normal,14917423-6bba-484c-b97b-b754ee072eb7,NA,NA +S125,C3N-00383,No,1,2,129C,C3N-00383-06,CPT0022850001,Adjacent_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.155400656,0.232,0.411,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180313_UNC32-K00270_0085_BHT2MGBBXX_AGTCAA_S42_L008_R1_001.fastq.gz,d8fdcaab-a8eb-452b-85d3-4e8342a5aa06,Adjacent_normal,180313_UNC32-K00270_0085_BHT2MGBBXX_AGTCAA_S42_L008_R2_001.fastq.gz,edbf898c-dc38-48e4-b61b-09f11115d61e,Adjacent_normal,c8f62f3e-d2b3-4db8-951d-01ce4207c713,NA,NA +S126,C3N-00729,No,2,6,128N,C3N-00729-06,CPT0064950001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.917,-0.00848,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S127,C3N-00858,No,1,1,127C,C3N-00858-05,CPT0078360001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.022841139,0.865,0.358,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180313_UNC32-K00270_0085_BHT2MGBBXX_CTTGTA_S41_L008_R1_001.fastq.gz,2bb35dfa-8915-4f44-a7f3-309bee055f37,Adjacent_normal,180313_UNC32-K00270_0085_BHT2MGBBXX_CTTGTA_S41_L008_R2_001.fastq.gz,c3a727a2-3121-46f4-8640-749db0e909dc,Adjacent_normal,bf011895-372c-4cca-b040-7bbc29d41958,NA,NA +S128,C3N-00866,No,2,8,127C,C3N-00866-03,CPT0063110001,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.115322032,1.22,-0.172,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,171205_UNC32-K00270_0069_BHN2HGBBXX_ATCACG_S17_L005_R1_001.fastq.gz,af76a34d-cc47-4d15-a276-60e3923b3975,Adjacent_normal,171205_UNC32-K00270_0069_BHN2HGBBXX_ATCACG_S17_L005_R2_001.fastq.gz,335d84c6-609f-4669-ae8c-2242a24a4fa8,Adjacent_normal,6eb569d3-8227-4a98-b7c1-16f8f6a10b22,NA,NA +S129,C3N-01346,No,4,13,127C,C3N-01346-05,CPT0116570003,Adjacent_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0,0.689,0.554,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Adjacent_normal,180516_UNC32-K00270_0095_AHTY5LBBXX_CGTACG_S5_L008_R1_001.fastq.gz,7f559a17-edd2-4465-aee8-61684540c52e,Adjacent_normal,180516_UNC32-K00270_0095_AHTY5LBBXX_CGTACG_S5_L008_R2_001.fastq.gz,a2d046e8-2efb-4587-8ac7-fb8e6e340b40,Adjacent_normal,aa96ca57-2981-45e4-9ad5-500df569e4f7,NA,NA +S130,C3L-00563,No,3,11,128C,C3L-00563-06,CPT0063260001,Myometrium_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.847,0.347,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S131,C3L-00605,No,3,12,127C,C3L-00605-06,CPT0063900001,Myometrium_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.839,0.802,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S132,C3L-00770,No,3,9,127C,C3L-00770-02,CPT0026660001,Myometrium_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.412,0.817,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S133,C3L-00771,No,3,11,127C,C3L-00771-02,CPT0026780001,Myometrium_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.368,-0.882,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S134,C3N-00200,No,3,9,128C,C3N-00200-06,CPT0017930001,Myometrium_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.176,0.404,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S135,C3N-01211,No,3,10,127C,C3N-01211-06,CPT0075940001,Myometrium_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.248,-0.387,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S136,NX1,No,4,13,128N,C3N-03691-01,"CPT0189160002,CPT0189160003",Enriched_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.526,1.92,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S137,NX2,No,4,13,128C,"C3N-03411-01,C3N-03411-02","CPT0182950002,CPT0182950003,CPT0182960002,CPT0182960003",Enriched_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.364,-1.23,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S138,NX3,No,4,14,127C,"C3N-03320-01,C3N-03320-03","CPT0182890003,CPT0182910002,CPT0182910003,CPT0182910004,CPT0182910005",Enriched_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.53,1.14,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S139,NX4,No,4,14,128N,"C3N-03692-01,C3L-03602-02,C3L-03602-03,C3L-03563-01,C3L-03567-01","CPT0191260002,CPT0191260003,CPT0191270002,CPT0191270003,CPT0191270004,CPT0189520005,CPT0186270003,CPT0186250002",Enriched_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.935,0.771,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S140,NX5,No,4,15,127C,"C3N-03692-01,C3N-03692-02,C3N-03692-03","CPT0189520002,CPT0189520003,CPT0189520004,CPT0189530004,CPT0189540002,CPT0189540003,CPT0189540004",Enriched_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.672,-0.52,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S141,NX6,No,4,15,128N,"C3N-03691-02,C3N-03691-03","CPT0189170002,CPT0189170003,CPT0189180002,CPT0189180003",Enriched_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.212,1.28,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S142,NX7,No,4,15,131,"C3N-03412-02,C3N-03413-01,C3N-03413-03,C3L-03564-01,C3N-03692-02","CPT0183020002,CPT0183050002,CPT0183050003,CPT0183070002,CPT0186240002,CPT0189530002,CPT0189530003",Enriched_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,1.29,0.426,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S143,NX8,No,4,16,127C,"C3L-03601-01,C3L-03601-02","CPT0191190002,CPT0191190003,CPT0191200002,CPT0191200003",Enriched_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.0845,0.767,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S144,NX9,No,4,16,128N,C3L-03601-03,"CPT0191210002,CPT0191210003,CPT0191210004",Enriched_normal,Yes,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.4,-0.53,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S145,NX10,No,5,17,129N,C3N-03693-03,"CPT0229850002,CPT0229850003",Enriched_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.467,-0.308,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S146,NX11,No,5,17,130C,C3N-03694-01,"CPT0229890002,CPT0229890003,CPT0229890004",Enriched_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.87,1.16,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S147,NX12,No,5,17,127N,"C3N-03695-01,C3N-03695-03","CPT0229950002,CPT0229950003,CPT0229970002,CPT0229970003",Enriched_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.289,0.573,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S148,NX13,No,5,17,128N,C3N-03697-03,"CPT0230030002,CPT0230030003,CPT0230030004",Enriched_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.709,1.05,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S149,NX14,No,5,17,128C,"C3N-03699-01,C3N-03699-02","CPT0230130002,CPT0230130003,CPT0230130004,CPT0230140002,CPT0230140003,CPT0230140004",Enriched_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.215,-0.0045,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S150,NX15,No,5,17,131,C3N-03700-01,"CPT0230190002,CPT0230190003,CPT0230190004",Enriched_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.558,0.614,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S151,NX16,No,5,17,129C,"C3N-03701-01,C3N-03701-02,C3N-03701-03","CPT0230250002,CPT0230260002,CPT0230270002,CPT0230270003,CPT0230270004",Enriched_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.139,-0.435,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S152,NX17,No,5,17,127C,"C3N-03706-01,C3N-03706-02,C3N-03706-03","CPT0230400002,CPT0230400003,CPT0230400004,CPT0230410002,CPT0230410003,CPT0230410004,CPT0230420002,CPT0230420003,CPT0230420004",Enriched_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.991,-0.874,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA +S153,NX18,No,5,17,130N,"C3N-03708-01,C3N-03708-02,C3N-03708-03","CPT0230460002,CPT0230460003,CPT0230460004,CPT0230470002,CPT0230470003,CPT0230470004,CPT0230480002,CPT0230480003,CPT0230480004",Enriched_normal,No,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.85,0.931,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA diff --git a/examples/datasets/Dou-ucec-ground-truth.csv b/examples/datasets/Dou-ucec-ground-truth.csv new file mode 100644 index 00000000..888ceed0 --- /dev/null +++ b/examples/datasets/Dou-ucec-ground-truth.csv @@ -0,0 +1,180 @@ +source,target +idx, +Proteomics_Participant_ID,Case_id +Case_excluded,Case_excluded +Proteomics_TMT_batch,Batch +Proteomics_TMT_plex,Plex +Proteomics_TMT_channel,ReporterName +Proteomics_Parent_Sample_IDs, +Proteomics_Aliquot_ID,Aliquot_ID +Proteomics_Tumor_Normal,Group +Proteomics_OCT, +Country,Participant_country +Histologic_Grade_FIGO,Histologic_grade +Myometrial_invasion_Specify,"Myometrial_invasion,Myometrial_invasion_present_specify" +Histologic_type,Histologic_Type +Treatment_naive,Cancer_history_history_of_any_treatment +Tumor_purity,ABSOLUTE_tumor_purity +Path_Stage_Primary_Tumor-pT,Pathologic_staging_primary_tumor_pt +Path_Stage_Reg_Lymph_Nodes-pN,Pathologic_staging_regional_lymph_nodes_pn +Clin_Stage_Dist_Mets-cM,Clinical_staging_distant_metastasis_cm +Path_Stage_Dist_Mets-pM, +tumor_Stage-Pathological,Tumor_stage_pathological +FIGO_stage, +LVSI, +BMI,BMI +Age,Age +Diabetes,Diabetes +Race,Race +Ethnicity,Ethnicity +Gender,Sex +Tumor_Site,Tumor_site +Tumor_Site_Other,Tumor_site_other +Tumor_Focality,Tumor_focality +Tumor_Size_cm,Tumor_size_cm +Estrogen_Receptor,Ancillary_studies_estrogen_receptor +Estrogen_Receptor_%, +Progesterone_Receptor,Ancillary_studies_progesterone_receptor +Progesterone_Receptor_%, +MLH1,Ancillary_studies_mlh1 +MLH2, +MSH6,Ancillary_studies_msh6 +PMS2,Ancillary_studies_pms2 +p53,Ancillary_studies_p53 +Other_IHC_specify, +MLH1_Promoter_Hypermethylation,Ancillary_studies_mlh1_promoter_hypermethylation +Num_full_term_pregnancies,Donor_information_number_of_full_term_pregnancies +EPIC_Bcells, +EPIC_CAFs, +EPIC_CD4_Tcells, +EPIC_CD8_Tcells, +EPIC_Endothelial, +EPIC_Macrophages, +EPIC_NKcells, +EPIC_otherCells, +CIBERSORT_B _cells _naive,Cibersort_B_cell_naive +CIBERSORT_B _cells _memory,Cibersort_B_cell_memory +CIBERSORT_Plasma _cells,Cibersort_B_cell_plasma +CIBERSORT_T _cells _CD8,Cibersort_T_cell_CD8+ +CIBERSORT_T _cells _CD4 _naive,Cibersort_T_cell_CD4+_naive +CIBERSORT_T _cells _CD4 _memory _resting,Cibersort_T_cell_CD4+_memory_resting +CIBERSORT_T _cells _CD4 _memory _activated,Cibersort_T_cell_CD4+_memory_activated +CIBERSORT_T _cells _follicular _helper,Cibersort_T_cell_follicular_helper +CIBERSORT_T _cells _regulatory _(Tregs),Cibersort_T_cell_regulatory_(Tregs) +CIBERSORT_T _cells _gamma _delta,Cibersort_T_cell_gamma_delta +CIBERSORT_NK _cells _resting,Cibersort_NK_cell_resting +CIBERSORT_NK _cells _activated,Cibersort_NK_cell_activated +CIBERSORT_Monocytes,Cibersort_Monocyte +CIBERSORT_Macrophages _M0,Cibersort_Macrophage_M0 +CIBERSORT_Macrophages _M1,Cibersort_Macrophage_M1 +CIBERSORT_Macrophages _M2,Cibersort_Macrophage_M2 +CIBERSORT_Dendritic _cells _resting,Cibersort_Myeloid_dendritic_cell_resting +CIBERSORT_Dendritic _cells _activated,Cibersort_Myeloid_dendritic_cell_activated +CIBERSORT_Mast _cells _resting,Cibersort_Mast_cell_resting +CIBERSORT_Mast _cells _activated,Cibersort_Mast_cell_activated +CIBERSORT_Eosinophils,Cibersort_Eosinophil +CIBERSORT_Neutrophils,Cibersort_Neutrophil +CIBERSORT_Absolute _score, +ESTIMATE_StromalScore,Estimate_StromalScore +ESTIMATE_ImmuneScore,Estimate_ImmuneScore +ESTIMATE_ESTIMATEScore,Estimate_ESTIMATEScore +Stemness_score, +ER_ESR1, +PR_PGR, +Pathway_activity_EGFR, +Pathway_activity_Hypoxia, +Pathway_activity_JAK.STAT, +Pathway_activity_MAPK, +Pathway_activity_NFkB, +Pathway_activity_PI3K, +Pathway_activity_TGFb, +Pathway_activity_TNFa, +Pathway_activity_Trail, +Pathway_activity_VEGF, +Pathway_activity_p53, +TP53_ATM, +TP53_CHEK2, +TP53_MDM4, +TP53_RPS6KA3, +TP53_TP53, +TP53_pathway, +PI3K_AKT1, +PI3K_AKT2, +PI3K_AKT3, +PI3K_DEPDC5, +PI3K_DEPTOR, +PI3K_INPP4B, +PI3K_MAPKAP1, +PI3K_MLST8, +PI3K_MTOR, +PI3K_NPRL2, +PI3K_NPRL3, +PI3K_PDK1, +PI3K_PIK3CA, +PI3K_PIK3CB, +PI3K_PIK3R1, +PI3K_PIK3R2, +PI3K_PPP2R1A, +PI3K_PTEN, +PI3K_RHEB, +PI3K_RICTOR, +PI3K_RPS6, +PI3K_RPS6KB1, +PI3K_RPTOR, +PI3K_STK11, +PI3K_TSC1, +PI3K_TSC2, +PI3K_pathway, +HRD_BRCA1, +HRD_BRCA2, +HRD_BRCA1_or_BRCA2, +CNV_DEL, +CNV_AMP, +CNV_class,CNV_status +CNV_idx, +CNV_1q_DEL, +CNV_3q_DEL, +CNV_4q_DEL, +CNV_1q_AMP, +CNV_3q_AMP, +CNV_4q_AMP, +Purity_Immune, +Purity_Cancer, +Purity_Stroma, +MSI_status,MSI_status +POLE_subtype,POLE +JAK1_MS_INDEL, +JAK1_Mutation, +Log2_variant_per_Mbp, +Log2_SNP_per_Mbp, +Log2_INDEL_per_Mbp, +Log2_variant_total, +Log2_SNP_total, +Log2_INDEL_total, +Genomics_subtype,Genomic_subtype +Mutation_signature_C>A, +Mutation_signature_C>G, +Mutation_signature_C>T, +Mutation_signature_T>C, +Mutation_signature_T>A, +Mutation_signature_T>G, +WXS_normal_sample_type, +WXS_normal_filename, +WXS_normal_UUID, +WXS_tumor_sample_type, +WXS_tumor_filename, +WXS_tumor_UUID, +WGS_normal_sample_type, +WGS_normal_UUID, +WGS_tumor_sample_type, +WGS_tumor_UUID, +RNAseq_R1_sample_type, +RNAseq_R1_filename, +RNAseq_R1_UUID, +RNAseq_R2_sample_type, +RNAseq_R2_filename, +RNAseq_R2_UUID, +miRNAseq_sample_type, +miRNAseq_UUID, +Methylation_available, +Methylation_quality, \ No newline at end of file diff --git a/examples/datasets/Huang.csv b/examples/datasets/Huang.csv new file mode 100644 index 00000000..15d54431 --- /dev/null +++ b/examples/datasets/Huang.csv @@ -0,0 +1,111 @@ +case_id,age,gender,country,smoking_history,smoke_age_start,smoke_age_stop,num_smoke_per_day,num_pack_years_sm,smoking_second_hand,smoking_inferred,alcohol_consum,num_yrs_alc_con,tumor_site_original,tumor_site_curated,tumor_focality,tumor_size_cm,histologic_type,histologic_grade,tumor_necrosis,patho_staging_pt,patho_staging_pn,clinic_staging_dist_metas,tumor_stage,P16,HPV_inference,NAT_pathology_review,tumor_pathology_review,ESTIMATE_stromal_score,ESTIMATE_immune_score,CD3_IHC_count,stemness_score,mutation_count,neoAntigen_count,chr_instability_idx,integrated_subtype,transcriptomic_subtype +C3L-00977,56,Male,Russia,"Current reformed smoker, years unknown",,,20,,Yes,strong_evidence,Lifelong non-drinker,,Floor of mouth,Oral cavity,Unifocal,1.2,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT1,pN1,cM0,Stage III,Not Evaluated,NO,Soft Tissue No EPI%,SCC 80%,6825.995755,7989.115925,1.0,0.953243158,106,0,2.003653988054,Basal,Mesenchymal +C3L-00987,61,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,18,,20,43.0,Yes,strong_evidence,"Consumed alcohol in the past, but currently a non-drinker",30,Tongue,Oral cavity,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT2,pN1,cM0,Stage III,Not Evaluated,NO,Soft Tissue No EPI;Normal No EPI%,SCC 90%;SCC 90%;SCC 80%;SCC 70%,5999.793467,4772.409716,0.0,0.825329743,83,0,5.20561174255834,CIN,Classical +C3L-00994,50,Male,Ukraine,Current reformed smoker within past 15 years,16,50,6,10.2,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,32,Tongue,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT2,pN0,cM0,Stage II,Not Evaluated,NO,Normal EPI 10%;Normal EPI 10%%,SCC 40%;SCC 70%;SCC 40%;SCC 75%,8924.036564,8176.233903,5.0,0.664581288,67,0,1.68447466240021,Immune,Mesenchymal +C3L-00995,56,Male,Ukraine,"Current reformed smoker, more than 15 years",25,56,20,31.0,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,31,Buccal mucosa,Oral cavity,Unifocal,4.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT2,pN1,cM0,Stage III,Not Evaluated,NO,Normal 15%;Normal 10%%,SCC 90%;SCC 80%;SCC 40%;SCC 70%,8723.429667,8342.246345,70.0,0.539918433,64,0,1.34048331636627,Immune,Mesenchymal +C3L-00997,47,Male,Ukraine,"Current reformed smoker, more than 15 years",12,27,20,15.0,Yes,strong_evidence,Lifelong non-drinker,,Oropharynx,Oropharynx,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT2,pN1,cM0,Stage II,Not Evaluated,NO,Normal 10%%,SCC 70%;SCC 70%,7025.911695,7445.251991,60.0,0.843765491,129,0,3.90636995096076,CIN,Classical +C3L-00999,56,Male,Russia,Current smoker: Includes daily and non-daily smokers,20,,20,36.0,Yes,weak_evidence,Lifelong non-drinker,,Floor of mouth,Oral cavity,Unifocal,2.2,"Squamous cell carcinoma, conventional",G1 Well differentiated,Present,pT2,pN0,cM0,Stage II,Not Evaluated,NO,Normal 10%%,SCC 80%;SCC 70%,8510.704551,8210.549555,30.0,0.548977169,159,0,1.1488341193973,Immune,Atypical +C3L-01138,62,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,8,,20,54.0,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,6.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT4a,pN1,cM0,Stage IV,Not Evaluated,NO,Normal 10%%,SCC 70%,6283.423855,6407.893478,10.0,0.890789746,187,1,3.92498169394758,Basal,Classical +C3L-01237,57,Male,Ukraine,"Current reformed smoker, more than 15 years",17,20,40,6.0,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Floor of mouth,Oral cavity,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN2,cM0,Stage IV,Not Evaluated,NO,Normal 10%%,SCC 80%,7175.667725,5720.287055,30.0,0.738328103,141,1,4.28648991074802,CIN,Classical +C3L-02617,64,Male,Bulgaria,Current smoker: Includes daily and non-daily smokers,20,,30,66.0,Yes,strong_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,20,Larynx,Larynx,Unifocal,6.0,"Squamous cell carcinoma, conventional",G3 Poorly differentiated,Present,pT2,pNX,Staging Incomplete,Stage II,Not Evaluated,NO,Normal 10%;Normal 15%;SCC 90%%,SCC 90%;SCC 80%;SCC 80%;SCC 80%;SCC 80%,6346.815584,6958.57339,,0.906466019,470,1,4.74481756440743,CIN,Classical +C3L-02621,68,Male,Bulgaria,Current smoker: Includes daily and non-daily smokers,38,,30,45.0,Yes,strong_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,20,Larynx,Larynx,Multifocal,0.6,"Squamous cell carcinoma, conventional",G3 Poorly differentiated,Present,pT1,pNX,Staging Incomplete,Stage I,Unknown,NO,Normal 10%;Normal 10%;Normal 10%%,SCC 70%;SCC 70%;SCC 70%;SCC 70%;SCC 65%,6806.384264,8039.787184,,0.754949822,358,0,1.77452097480929,CIN,Atypical +C3L-02651,81,Male,Bulgaria,Current smoker: Includes daily and non-daily smokers,29,,30,78.0,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,2.5,Keratinizing Squamous Cell Carcinoma,G2 Moderately differentiated,Present,pT2 ,pNX,cMX,Stage II,Not Evaluated,NO,Normal 40%;Normal 20%;Normal 15%%,SCC 70%;SCC 70%;SCC 70%;SCC 70%;SCC 70%,7397.640049,8476.382275,,0.6098734,402,0,2.00013239240149,,Mesenchymal +C3L-03378,54,Male,Russia,Current smoker: Includes daily and non-daily smokers,20,,20,34.0,Yes,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Oral cavity,Oral cavity,Unifocal,1.8,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT4a,pN2c,cM0,Stage IV,Not Evaluated,NO,Normal 15%%,SCC (PD) 70%,6878.201534,6924.419568,60.0,0.835631289,211,0,3.94351240948061,CIN,Classical +C3L-04025,69,Male,Bulgaria,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,No or minimal exposure to secondhand smoke,weak_evidence,,,Buccal mucosa,Oral cavity,Unifocal,1.5,,G2 Moderately differentiated,Not identified,pT1b,pNX,,Stage I,,NO,SCC 70%;Normal 10%;Normal 30%%,SCC 70%;WDSCC 65%;WDSCC 70%;Verrucous Non-Invasive 40%;WDSCC 70%,7562.669184,7805.771365,,0.519337914,30,0,0.379356903896177,Immune,Mesenchymal +C3L-04354,60,Male,Bulgaria,Current smoker: Includes daily and non-daily smokers,30,,6,9.0,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,2.0,Non-Keratinized Squamous Cell Carcinoma,G3 Poorly differentiated,Present,pT2 ,pNX,cMX,Stage II,Not Evaluated,NO,Normal 20%;Normal No EPI;Normal 5%%,SCC 75%;SCC 50%;SCC 55%;SCC 70%;SCC 75%,7228.703512,8055.848268,,0.618746239,180,0,3.70515533981302,CIN,Atypical +C3L-04791,81,Male,Bulgaria,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,No or minimal exposure to secondhand smoke,weak_evidence,Lifelong non-drinker,,Larynx,Larynx,Unifocal,3.0,Keratinizing Squamous Cell Carcinoma,G2 Moderately differentiated,Present,pT1,pNX,cMX,Stage I,Not Evaluated,NO,Normal Thyroid;Normal Thyroid;Normal No EPI%,SCC 70%;SCC 75%;SCC 75%;SCC 70%;SCC 65%,6837.579096,7804.981646,,0.648402377,478,0,1.62512892038396,Immune,Mesenchymal +C3L-04844,61,Female,TSS did not collect,Current smoker: Includes daily and non-daily smokers,21,,,,Exposure to secondhand smoke history not available,weak_evidence,,,Tonsil,Oropharynx,Unifocal,6.0,,G2 Moderately differentiated,Not identified,pT4a,pN3,,Stage IV,,NO,Normal 70$ EPI%,SCC 75%;SCC 70%,5714.862795,5923.495615,40.0,0.776764448,306,1,5.33285310739406,Basal,Classical +C3L-04849,63,Male,TSS did not collect,Current smoker: Includes daily and non-daily smokers,18,,,,Exposure to secondhand smoke history not available,strong_evidence,,,Floor of mouth,Oral cavity,Unifocal,4.7,,G2 Moderately differentiated,Present,pT4a,pN3,,Stage IV,,NO,Hyperplasia 70%%,SCC 70%;SCC 75%,5757.546725,5841.490604,60.0,0.914700396,133,0,3.88309123002414,Basal,Basal +C3N-00204,63,Female,Bulgaria,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,strong_evidence,Lifelong non-drinker,,Larynx,Larynx,Unifocal,3.2,Adenosquamous carcinoma,G3 Poorly differentiated,Not identified,pT3,pN1,cM0,Stage III,Not Evaluated,NO,Normal 15%;Normal 5%%,SCC 80%;PDSCC 80%;PDSCC 70%;PDSCC 75%,4141.503954,5229.928241,60.0,0.953230425,920,0,5.11464835682004,CIN,Atypical +C3N-00295,53,Female,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,2.2,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pNX,cM0,Stage III,Negative,NO,Normal 40%%,SCC 40%;SCC 70%;SCC 65%;SCC 10%,4752.639319,4989.340444,,0.736752931,319,0,1.3612300289131,,Atypical +C3N-00297,69,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,3.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN0,cM0,Stage II,Negative,NO,Normal no EPI%,SCC 80%;SCC 70%;SCC 80%;SCC 80%,5822.516855,6936.01723,,0.541769935,125,0,1.94171116940674,Basal,Basal +C3N-00299,54,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption history not available,,Lip,Lip,Unifocal,3.1,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN0,cM0,Stage II,Negative,NO,Normal 0% EPI%,SCC 80%;SCC 80%;C3N-00299-23;SCC 65%,5342.360428,8009.515355,,0.848396164,1065,0,1.15797080609525,Basal,Basal +C3N-00306,50,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN0,cM0,Stage III,Negative,NO,Normal 20% EPI%,SCC 50%;SCC 65%;SCC 65%;SCC 45%,6485.079143,7685.055639,,0.567681993,128,0,1.76612222075637,Immune,Atypical +C3N-00307,70,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,3.0,"Squamous cell carcinoma, conventional",G3 Poorly differentiated,Not identified,pT4a,pNX,cM0,Stage IV,Negative,NO,Normal 40%%,SCC 70%;SCC 70%;SCC 70%;SCC 50%,7021.274977,7008.902307,,0.537980522,104,0,2.1452103279025,CIN,Mesenchymal +C3N-00498,63,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Oral cavity,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN1,cM0,Stage III,Positive (>70% nuclear and cytoplasmic staining),NO,Normal 15%%,SCC 45%;SCC 75%;SCC 75%;SCC 60%,5288.872044,4377.867323,,0.790722164,168,0,4.00349897691078,CIN,Classical +C3N-00519,67,Male,Poland,"Current reformed smoker, more than 15 years",27,67,20,40.0,Exposure to secondhand smoke history not available,weak_evidence,"Consumed alcohol in the past, but currently a non-drinker",5,Larynx,Larynx,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN0,cM0,Stage II,Negative,NO,Normal 15%%,SCC 70%;SCC 70%;SCC 70%;SCC 70%,7349.981429,8246.069477,,0.601852135,177,0,1.02047609395444,Immune,Atypical +C3N-00822,53,Female,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,2.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN0,cM0,Stage III,Negative,NO,SCC 75%%,SCCPD 80%;SCC 75%,4080.16184,4864.02235,50.0,0.928850145,87,0,3.84953493276764,CIN,Classical +C3N-00825,53,Male,Poland,Current smoker: Includes daily and non-daily smokers,30,,22,25.3,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption history not available,,Tongue,Oral cavity,Multifocal,2.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN0,cM0,Stage II,Negative,NO,Muscle 0%%,SCC 55%;SCC 70%,8446.53344,8615.897442,90.0,0.709392947,55,0,1.35009015654592,Immune,Mesenchymal +C3N-00828,67,Male,Poland,"Current reformed smoker, more than 15 years",16,66,20,50.0,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pNX,cM0,Stage II,Negative,NO,Normal 0%%,SCC 70%;SCC 70%;SCC 60%;SCC 40%,5428.79908,6486.859053,,0.736569263,326,0,2.37739360499887,CIN,Atypical +C3N-00829,53,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Tongue,Oral cavity,Unifocal,2.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN2b,cM0,Stage IV,Negative,NO,Normal 20%%,SCC 5%;SCC 10%;SCC 50%;SCC 45%,5642.230086,5786.945507,,0.785402648,173,0,3.85563750134117,CIN,Classical +C3N-00846,67,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,37,,10,15.0,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Tongue,Oral cavity,Unifocal,2.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT1,pNX,cM0,Stage I,Negative,NO,Normal 5%%,SCC 40%;SCC 45%;SCC 40%,8456.142513,9176.55781,,0.444508155,71,0,0.716663307509181,Immune,Mesenchymal +C3N-00857,64,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN1,cM0,Stage IV,Not Evaluated,NO,Normal 25%%,SCC 60%;SCC 60%,5797.846142,4785.847019,1.0,0.862813515,175,0,7.02195799661206,CIN,Classical +C3N-00871,58,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Oral cavity,Oral cavity,Unifocal,5.2,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN2b,cM0,Stage IV,Not Evaluated,NO,Normal 0%%,SCC 70%;SCC 75%,6278.855658,5085.878714,5.0,0.729252757,140,0,4.90384927675463,Basal,Classical +C3N-01337,52,Male,Poland,Current smoker: Includes daily and non-daily smokers,30,,12,13.2,Yes,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,5.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT4,pN2b,cM0,Stage IV,Negative,NO,Normal 15%%,SCC 80%;SCC 75%,5650.929868,7269.184407,10.0,0.768039988,133,0,1.97256829789542,Basal,Atypical +C3N-01338,50,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,3.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN1,cM0,Stage III,Negative,NO,Normal Cartilage%,SCC 75%;SCC 75%,6117.170351,6477.301118,20.0,0.982769201,265,0,2.74001252017641,Basal,Classical +C3N-01339,68,Female,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,3.4,"Squamous cell carcinoma, conventional",G3 Poorly differentiated,Present,pT4,pN1,cM0,Stage IV,Not Evaluated,NO,SCC 70%%,SCC 75%;SCC 70%,2933.655697,3813.652536,10.0,0.623259258,234,1,7.29780757538092,CIN,Classical +C3N-01340,72,Male,Poland,"Current reformed smoker, more than 15 years",Unknown,Unknown,Unknown,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN0,cM0,Stage IV,Not Evaluated,NO,Normal 15%%,SCC 70%;SCC 70%,7441.043447,7793.863113,40.0,0.628752325,91,1,2.1182168893068,,Atypical +C3N-01620,56,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,4.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN0,cM0,Stage III,Negative,NO,Normal 20%%,SCC 10%;SCC 60%,7332.918086,7128.615543,10.0,0.675434802,163,1,2.73819535791519,Basal,Mesenchymal +C3N-01643,68,Male,Poland,"Current reformed smoker, more than 15 years",25,52,40,54.0,No or minimal exposure to secondhand smoke,weak_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,2.6,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN0,cM0,Stage III,Not Evaluated,NO,,WDSCC 70%;WDSCC 70%,6013.691797,5045.364024,30.0,0.556834589,5,0,,,Atypical +C3N-01645,71,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN0,cM0,Stage III,Negative,NO,Normal 20%%,SCC 75%;SCC 70%,7001.081675,8716.71833,50.0,0.856966154,100,0,1.78347187054584,,Mesenchymal +C3N-01752,73,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Floor of mouth,Oral cavity,Unifocal,5.6,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN0,cM0,Stage IV,Not Evaluated,NO,,WDSCC 65%;WDSCC 70%,5441.75976,4353.059497,1.0,0.967646007,127,0,5.62117793084445,Basal,Basal +C3N-01754,64,Male,Poland,Current reformed smoker within past 15 years,22,63,20,41.0,Yes,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Tongue,Oral cavity,Unifocal,4.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT3,pN0,cM0,Stage III,Not Evaluated,NO,Normal 50%%,SCC 20%;SCC 70%;SCC 70%;SCC 40%,6759.178398,6021.776653,10.0,0.839918856,104,0,4.15894563931942,Basal,Basal +C3N-01755,68,Male,Poland,"Current reformed smoker, years unknown",,,20,,Yes,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,5.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,PN1,cM0,Stage III,Not Evaluated,NO,,SCC 40%;SCC 75%;SCC 75%,6898.079644,6962.033648,20.0,0.68876914,110,0,4.51263623323375,CIN,Mesenchymal +C3N-01756,62,Male,Poland,Current smoker: Includes daily and non-daily smokers,17,,10,22.5,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Hypopharynx,Unifocal,4.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN2c,cM0,Stage IV,Not Evaluated,NO,Normal 20%%,SCC 70%,5657.98446,4670.155568,20.0,0.878652596,100,1,4.95775000978713,CIN,Classical +C3N-01757,64,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,2.7,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pNx,cM0,Stage II,Not Evaluated,NO,Normal 40%%,SCC 40%;Poor Quality 70%;Poor Quality 70%;SCC 70%,6179.545402,7014.534802,50.0,0.790684392,153,0,1.96924161753749,Basal,Basal +C3N-01758,59,Male,Poland,Current reformed smoker within past 15 years,19,59,15,30.0,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Floor of mouth,Oral cavity,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT4a,pN1,cM0,Stage IV,Not Evaluated,NO,Normal 10%%,SCC 75%;SCC 70%;SCC 75%,8044.356402,7692.143579,60.0,0.606988683,71,0,2.49177658079283,Basal,Mesenchymal +C3N-01858,62,Male,Poland,Current reformed smoker within past 15 years,21,62,30,61.5,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,15,Larynx,Larynx,Unifocal,3.2,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN3b,cM0,Stage IV,Not Evaluated,NO,Normal 20%%,SCC 60%;SCC 75%,6267.242797,7198.497771,50.0,0.901155495,1349,4,0.944560823285874,,Classical +C3N-01859,67,Male,Poland,Current reformed smoker within past 15 years,17,57,20,40.0,Yes,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,3.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT4a,pN2c,cM0,Stage IV,Not Evaluated,NO,Normal 30%%,SCC 70%,6152.014132,8019.669666,60.0,0.817627441,239,1,4.16638343784538,CIN,Atypical +C3N-01943,63,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,5.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN3a,cM0,Stage IV,Not Evaluated,NO,Normal 60%%,SCC 70%;PDSCC 75%,4803.753271,7256.040173,80.0,0.872400321,131,1,2.5047317619498,CIN,Atypical +C3N-01944,65,Male,Poland,Current smoker: Includes daily and non-daily smokers,20,,20,45.0,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Tongue,Oral cavity,Unifocal,3.5,"Squamous cell carcinoma, conventional",G3 Poorly differentiated,Present,pT4a,pN1,cM0,Stage IV,Not Evaluated,NO,Normal 10%%,SCC 50%,7719.467126,7379.857472,40.0,0.668452661,106,0,2.62992562733775,Basal,Mesenchymal +C3N-01945,61,Male,Poland,"Current reformed smoker, more than 15 years",Unknown,Unknown,20,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN1,cM0,Stage III,Not Evaluated,NO,Normal 1%%,Verrucous Non-Invasive 75%;SCC 70%,6931.64948,6694.529778,30.0,0.801326397,96,0,2.04989486079862,CIN,Classical +C3N-01946,64,Male,Poland,Current reformed smoker within past 15 years,Unknown,Unknown,Unknown,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Larynx,Larynx,Unifocal,1.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN0,cM0,Stage II,Not Evaluated,NO,Normal 60%%,SCC 90%,7320.801741,9805.370561,70.0,0.66500437,1273,3,1.27788803688656,Immune,Mesenchymal +C3N-01947,49,Male,Poland,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Floor of mouth,Oral cavity,Unifocal,5.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN2b,cM0,Stage IV,Not Evaluated,NO,Normal 50%%,SCC 90%,8369.540985,9086.657983,80.0,0.599903474,76,0,1.83309695660605,Immune,Mesenchymal +C3N-01948,55,Female,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption history not available,,Tongue,Oral cavity,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN2b,cM0,Stage IV,Not Evaluated,NO,Normal 5%%,SCC 65%;SCC 70%,7706.958045,9307.146827,80.0,0.629910425,66,0,0.915735252846995,Immune,Atypical +C3N-02275,69,Male,Poland,Smoking history not available,,,,,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption history not available,,Larynx,Larynx,Unifocal,3.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN0,cM0,Stage IV,Not Evaluated,NO,Normal 10%%,SCC 50%;SCC 70%,6171.891354,8593.664692,50.0,0.749940074,747,5,1.74267053678057,Basal,Mesenchymal +C3N-02279,59,Male,Poland,Current reformed smoker within past 15 years,20,59,20,39.0,Yes,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT3,pN0,cM0,Stage III,Not Evaluated,NO,Normal 10%%,SCC 50%,6815.19623,7399.477079,70.0,0.835648725,180,0,2.60095072588305,Basal,Basal +C3N-02333,61,Male,Ukraine,Current reformed smoker within past 15 years,Unknown,59,20,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT4a,pNX,cM0,Stage IV,Negative,NO,Normal 5%%,SCC 85%;SCC 85%;SCC 75%,7348.023786,9022.349073,50.0,0.526531556,345,0,0.623878944989433,Immune,Mesenchymal +C3N-02693,42,Male,Poland,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,No or minimal exposure to secondhand smoke,weak_evidence,Lifelong non-drinker,,Larynx,Larynx,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN0,cM0,Stage III,Not Evaluated,YES,Normal 40%%,SCC 85%,5143.846834,7273.096915,70.0,0.805646109,178,1,1.66689666383698,,Atypical +C3N-02694,57,Male,Poland,"Current reformed smoker, years unknown",,,15,,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Tongue,Oral cavity,Unifocal,2.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN2b,cM0,Stage IV,Not Evaluated,NO,,SCC 85%;SCC 50%,8945.001701,9361.656935,,0.515325924,80,0,1.44569881644837,Immune,Mesenchymal +C3N-02695,45,Male,Poland,Current smoker: Includes daily and non-daily smokers,17,,12,16.8,No or minimal exposure to secondhand smoke,weak_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Floor of mouth,Oral cavity,Multifocal,5.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT3,pN0,cM0,Stage III,Not Evaluated,NO,Normal 5%%,SCC 80%;SCC 80%,5937.036833,7022.660147,,0.755947066,87,0,2.04458209841523,Basal,Basal +C3N-02700,80,Female,Ukraine,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Lip,Lip,Unifocal,3.5,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT2,pNX,cM0,Stage II,Positive (>70% nuclear and cytoplasmic staining),NO,Normal 5%%,SCC 80%;SCC 70%;SCC 80%,5691.04835,8128.32296,40.0,0.764721737,1372,2,2.23034641623138,Basal,Basal +C3N-02713,64,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,19,,20,45.0,Exposure to secondhand smoke history not available,strong_evidence,Lifelong non-drinker,,Larynx,Larynx,Unifocal,3.3,"Squamous cell carcinoma, conventional",G3 Poorly differentiated,Present,pT3,pN2,cM0,Stage IV,Not Evaluated,NO,Normal 10%%,SCC 70%;SCC 80%;PDSCC 80%,5396.144947,5220.095945,60.0,0.797822192,638,0,5.22744392960231,CIN,Classical +C3N-02714,23,Male,Ukraine,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Tongue,Oral cavity,Unifocal,2.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT2,pNX,cM0,Stage II,Positive (>70% nuclear and cytoplasmic staining),NO,Normal 15%%,PDSCC 70%;SCC 25%;SCC 75%,7581.433954,8894.705175,80.0,0.612150111,54,0,0.969092228014795,Immune,Mesenchymal +C3N-02716,76,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,Unknown,,Unknown,,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Lip,Lip,Unifocal,1.2,"Squamous cell carcinoma, conventional",G1 Well differentiated,Present,pT1,pNX,cM0,Stage I,Positive (>70% nuclear and cytoplasmic staining),NO,,SCC 70%;SCC 45%,7083.32021,7778.97507,40.0,0.600350747,1270,1,0.105650080165848,Immune,Atypical +C3N-02727,49,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,Unknown,,20,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,3.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT4a,pNX,cM0,Stage IV,Negative,NO,Normal Cartilage 0%%,SCC 60%;SCC 70%;SCC 90%,8801.307424,9307.036194,60.0,0.471334213,33,0,1.15493404518317,Immune,Mesenchymal +C3N-02730,40,Male,China,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Tongue,Oral cavity,Unifocal,2.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT1,pN1,cM0,Stage III,Not Evaluated,NO,Normal 5%%,SCC 75%;SCC 75%,8943.570062,9868.225196,,0.55895911,18,1,0.839975841114401,Immune,Mesenchymal +C3N-02925,68,Female,China,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Tongue,Oral cavity,Unifocal,4.2,Keratinizing squamous cell carcinoma,G2 Moderately differentiated,Not identified,pT3,pN2b,cM0,Stage IV,Not Evaluated,NO,Normal 0%%,SCC 85%;SCC 70%,7089.288448,9904.398057,,0.645009581,36,0,1.27973286026081,Immune,Basal +C3N-03008,65,Female,Poland,Current smoker: Includes daily and non-daily smokers,20,,10,22.5,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,5,Floor of mouth,Oral cavity,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN2c,cM0,Stage IV,Not Evaluated,NO,Normal 40%%,SCC 70%,7532.452338,6864.752029,5.0,0.809266623,156,0,3.78656476415432,Basal,Mesenchymal +C3N-03009,58,Male,Poland,Current smoker: Includes daily and non-daily smokers,16,,15,31.5,Yes,strong_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,Unknown,Floor of mouth,Oral cavity,Unifocal,2.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT1,pN0,cM0,Stage I,Not Evaluated,NO,Normal 35%%,SCC 75%;SCC sub 5%,6797.453417,5131.34755,60.0,0.836561377,129,0,5.10284989127249,CIN,Classical +C3N-03011,62,Male,Poland,Current reformed smoker within past 15 years,22,60,20,38.0,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,2.0,"Squamous cell carcinoma, conventional",G3 Poorly differentiated,Not identified,pT2,pN2b,cM0,Stage IV,Not Evaluated,NO,Normal 35%%,SCC 80%;SCC 70%;SCC 75%,5274.918068,6830.57982,40.0,0.831950566,67,0,5.05942043387248,CIN,Atypical +C3N-03012,71,Male,Poland,"Current reformed smoker, years unknown",,,20,,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN0,cM0,Stage IV,Unknown,NO,Normal 35%%,Normal 35%,6716.016019,4492.50941,0.0,0.83083229,343,0,6.12072466423461,CIN,Classical +C3N-03013,59,Male,Poland,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Tongue,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pNx,cM0,Stage II,Not Evaluated,NO,Normal 10%%,SCC 65%,8855.514614,8805.211906,50.0,0.526153678,67,0,0.965558835675723,Immune,Atypical +C3N-03015,61,Male,Poland,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Floor of mouth,Oral cavity,Unifocal,1.0,"Squamous cell carcinoma, conventional",G3 Poorly differentiated,Not identified,pT4a,pN2b,cM0,Stage IV,Not Evaluated,NO,Normal 10%%,SCC 75%,7041.91195,8271.449708,70.0,0.898778348,192,0,1.79904050588596,Basal,Atypical +C3N-03027,65,Male,Poland,Current smoker: Includes daily and non-daily smokers,17,,20,48.0,No or minimal exposure to secondhand smoke,weak_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,8,Floor of mouth,Oral cavity,Unifocal,1.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pNx,cM0,Stage II,Not Evaluated,NO,Normal 35%%,SCC 75%,5566.75901,7101.798643,80.0,0.808283426,118,0,2.7927541433259,CIN,Atypical +C3N-03028,59,Male,Poland,Current smoker: Includes daily and non-daily smokers,20,,20,39.0,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,Unknown,Floor of mouth,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN2b,cM0,Stage IV,Not Evaluated,NO,Normal 35%%,SCC 80%,7353.736545,7831.873692,30.0,0.79897701,95,0,3.72064406197502,Basal,Mesenchymal +C3N-03042,67,Female,United States,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,,,Oral cavity,Oral cavity,Unifocal,5.2,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,T4a,N3b,M0,Stage IV,Negative,NO,SCC 30%;SCC 20%%,SCC 80%;SCC 75%;SCC 75%;SCC 75%,6460.922624,5907.724612,40.0,0.822779851,98,0,2.52459111000182,Basal,Mesenchymal +C3N-03045,77,Male,United States,Smoking history not available,,,,,Exposure to secondhand smoke history not available,strong_evidence,,,Tongue,Oral cavity,Unifocal,2.2,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,T2,N1,m0,Stage III,Negative,NO,Normal 10%%,SCC 75%,4932.8686,6125.854309,10.0,0.919189035,123,0,3.49683744220641,Basal,Basal +C3N-03226,54,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,19,,20,35.0,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Tongue,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN2b,cM0,Stage IV,Not Evaluated,NO,Normal 5%%,SCC 80%;SCC 70%;SCC 70%,7725.028018,8410.581778,50.0,0.670113161,41,0,0.773082844406719,Immune,Atypical +C3N-03433,76,Male,Poland,Current smoker: Includes daily and non-daily smokers,22,,15,40.5,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Tongue,Oral cavity,Unifocal,2.4,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN0,cM0,Stage II,Not Evaluated,NO,Normal%,SCC 7,6426.336016,7166.765405,60.0,0.755758699,459,0,4.44642896396794,CIN,Classical +C3N-03456,64,Male,Poland,Current smoker: Includes daily and non-daily smokers,23,,20,41.0,Yes,strong_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,Unknown,Floor of mouth,Oral cavity,Unifocal,7.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4,pN0,cM0,Stage IV,Not Evaluated,NO,,SCC 6,6439.29269,5545.333423,50.0,0.809361582,92,0,4.62246547991071,CIN,Classical +C3N-03457,71,Male,Poland,Current reformed smoker within past 15 years,22,71,15,36.8,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Floor of mouth,Oral cavity,Unifocal,2.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN0,cM0,Stage II,Not Evaluated,NO,Normal%,SCC 70,9627.987701,9020.741798,30.0,0.468432263,236,0,1.66045021314332,Immune,Mesenchymal +C3N-03458,70,Male,Poland,Current smoker: Includes daily and non-daily smokers,25,,,,Yes,weak_evidence,,,Floor of mouth,Oral cavity,Unifocal,2.0,,G1 Well differentiated,Not identified,pT2,pN0,,Stage II,,NO,Normal%,SCC 65,6027.079084,6746.609023,20.0,0.896479674,124,1,2.48177344048731,Basal,Atypical +C3N-03487,53,Female,Ukraine,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Alveolar ridge,Oral cavity,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT4a,pN0,cM0,Stage IV,Not Evaluated,NO,Normal%,SCC 8;SCC 80%;SCC 80%,8134.452066,9299.472289,90.0,0.577214475,81,0,0.935948972579417,Immune,Mesenchymal +C3N-03488,64,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,19,,20,45.0,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Other,Hypopharynx,Unifocal,5.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT3,pNX,cM0,Stage III,Not Evaluated,NO,Normal 20%;SCC 75%%,SCC 80%;SCC 35%,7020.822857,5614.264427,50.0,0.862958537,113,0,5.16260413236008,Basal,Mesenchymal +C3N-03490,64,Male,Ukraine,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,strong_evidence,Lifelong non-drinker,,Base of tongue,Oropharynx,Unifocal,4.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pN0,cM0,Stage III,Not Evaluated,NO,N 10%%,SCC 70%;SCC 75%;SCC 80%,6984.498413,6145.297042,30.0,0.816379845,136,1,5.88394907689529,CIN,Classical +C3N-03612,51,Male,Ukraine,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Oropharynx,Oropharynx,Unifocal,2.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT3,pNX,cM0,Stage III,Not Evaluated,NO,N 10%%,PDSCC 15%;SCC 35%;SCC 65%,5983.808904,10678.10984,60.0,0.442356796,1,0,0.0997933869043518,Immune,Atypical +C3N-03619,59,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,24,,20,35.0,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Tongue,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT2,pN0,cM0,Stage II,Not Evaluated,NO,N 5%%,SCC 60%;SCC 25%;SCC 70%,7000.525344,7267.440427,50.0,0.723910132,90,0,2.60534793715202,,Atypical +C3N-03620,61,Male,Ukraine,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Tongue,Oral cavity,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pNX,cM0,Stage II,Not Evaluated,NO,N 5%%,SCC 70%;PDSCC 10;SCC 10%,8784.023801,9562.408984,90.0,0.495209781,14,0,0.852501028951453,Immune,Atypical +C3N-03664,58,Male,Ukraine,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,strong_evidence,Lifelong non-drinker,,Floor of mouth,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN2c,cM0,Stage IV,Not Evaluated,NO,N 5%%,SCC 65%;SCC 80%;SCC 75%,6235.504976,5794.499567,20.0,0.942451279,165,1,5.70162561583804,Basal,Atypical +C3N-03781,68,Male,Poland,"Current reformed smoker, more than 15 years",28,50,20,22.0,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN0,cM0,Stage IV,Not Evaluated,NO,N 20%%,SCC 60%,7985.804043,7107.47205,70.0,0.659516899,193,0,2.43825988238678,,Mesenchymal +C3N-03782,50,Female,Poland,Current smoker: Includes daily and non-daily smokers,20,,20,30.0,Yes,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Floor of mouth,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT4a,pN0,cM0,Stage IV,Not Evaluated,NO,N 10%%,SCC 65%,5188.792619,4993.8734,50.0,0.862910851,95,0,4.84870972785454,Basal,Atypical +C3N-03783,67,Male,Poland,Current smoker: Includes daily and non-daily smokers,17,,20,50.0,Yes,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Alveolar ridge,Oral cavity,Unifocal,2.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT2,pN2b,cM0,Stage IV,Not Evaluated,NO,N lymphoid B%,SCC 70%,8012.368622,8451.386202,80.0,0.747829853,123,1,2.66572270641339,,Mesenchymal +C3N-03785,66,Male,Poland,Current smoker: Includes daily and non-daily smokers,20,,4,9.2,Yes,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Tongue,Oral cavity,Multifocal,1.2,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT1,pNx,cM0,Stage I,Not Evaluated,NO,N 3%%,SCC(PD) 60,3037.218187,4178.197713,1.0,0.892066902,153,0,7.40131209605744,CIN,Atypical +C3N-03837,54,Male,China,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Lip,Lip,Unifocal,4.5,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT3,pN0,cM0,Stage III,Not Evaluated,NO,N 35%%,SCC 80%;SCC 80%,6229.92831,8003.79671,,0.720749789,459,0,0.701179286406038,,Basal +C3N-03841,59,Male,China,Current smoker: Includes daily and non-daily smokers,25,,20,34.0,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,30,Other,Larynx,Unifocal,3.0,"Squamous cell carcinoma, conventional",G3 Poorly differentiated,Not identified,pT3,pN1,cM0,Stage III,Not Evaluated,NO,N 15%%,SCC 75%;SCC 75%,7057.917607,9004.291325,,0.684330926,96,0,3.98363706191443,CIN,Mesenchymal +C3N-03849,55,Male,China,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Larynx,Larynx,Unifocal,7.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT4a,pN2b,cM0,Stage IV,Not Evaluated,NO,N 15%%,PDCasub 70%;SCC 25%,6188.218272,6250.864705,,0.861893118,118,0,3.41718750957631,CIN,Atypical +C3N-03876,65,Male,China,"Current reformed smoker, more than 15 years",22,44,20,22.0,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption more than 2 drinks per day for men and more than 1 drink per day for women,20,Larynx,Larynx,Unifocal,2.5,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT3,pN2b,cM0,Stage IV,Unknown,NO,N 15%%,PDCa 70%;SCC 80%,5555.585958,5729.003577,,1.0,151,0,5.49628737944634,Basal,Classical +C3N-03878,52,Male,China,Current smoker: Includes daily and non-daily smokers,32,,10,10.0,Exposure to secondhand smoke history not available,strong_evidence,Lifelong non-drinker,,Larynx,Larynx,Unifocal,2.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT3,pN1,cM0,Stage III,Not Evaluated,NO,N 10%%,SCC 70%;SCC 80%,6917.552525,6868.706676,,0.65847816,80,0,3.00168256433835,CIN,Classical +C3N-03888,58,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,18,,20,40.0,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,2.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT3,pNX,cM0,Stage III,Not Evaluated,NO,N 20%%,SCC 30%;PDCa 70%;SCC 40%,4789.748963,6802.39559,30.0,0.857808178,125,0,4.02272702037636,CIN,Atypical +C3N-03889,53,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,23,,20,30.0,Exposure to secondhand smoke history not available,weak_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Alveolar ridge,Oral cavity,Unifocal,4.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT4a,pN0,cM0,Stage IV,Not Evaluated,NO,N 10%%,SCC 75%;SCC 80%;SCC 70%,7941.455222,7219.722156,20.0,0.596663601,91,0,2.43824716654285,Immune,Mesenchymal +C3N-03928,60,Female,Ukraine,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Tongue,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Present,pT2,pN1,cM0,Stage III,Not Evaluated,NO,N 15%%,SCC 70%;SCC 40%;SCC 70%,7661.031806,9098.218537,50.0,0.625748343,61,0,1.84477084641962,Immune,Basal +C3N-03933,70,Female,Ukraine,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,weak_evidence,Lifelong non-drinker,,Floor of mouth,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT2,pN1,cM0,Stage III,Not Evaluated,NO,N 15%%,SCC 50%;SCC 70%;SCC 75%,7146.623165,7900.354223,80.0,0.689933031,87,1,5.48543676505158,Basal,Basal +C3N-04152,54,Male,Armenia,Lifelong non-smoker: Less than 100 cigarettes smoked in lifetime,,,,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Oropharynx,Oropharynx,Unifocal,4.5,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT4a,pN2b,cM0,Stage IV,Not Evaluated,NO,N 5%%,SCC PD 60%;PDSCC 75%;PDC 70%,5153.497308,4863.601322,70.0,0.94586735,80,0,6.51261649605658,CIN,Atypical +C3N-04273,73,Male,Poland,Current reformed smoker within past 15 years,30,68,20,38.0,No or minimal exposure to secondhand smoke,strong_evidence,"Consumed alcohol in the past, but currently a non-drinker",Unknown,Oropharynx,Oropharynx,Unifocal,2.0,Basaloid squamous cell carcinoma,G2 Moderately differentiated,Present,pT2,pN2b,cM0,Stage IV,Not Evaluated,NO,N 0%%,PDCa 75%;PDCa 65%,4786.757912,4495.994769,40.0,0.746277202,111,0,7.02321458831796,CIN,Atypical +C3N-04275,61,Male,Poland,Current smoker: Includes daily and non-daily smokers,20,,20,41.0,Yes,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,2.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT2,pN0,cM0,Stage II,Not Evaluated,NO,N 35%%,SCC 70%,6635.873278,8210.346626,50.0,0.451905628,82,0,1.15390024252283,Immune,Atypical +C3N-04276,68,Male,Poland,Current reformed smoker within past 15 years,16,65,15,36.8,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,5.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT4a,pN0,cM0,Stage IV,Not Evaluated,NO,N 10%%,PDCa 70%,6821.83286,5143.929607,5.0,0.51276159,165,0,5.19925706608648,CIN,Mesenchymal +C3N-04277,72,Male,Poland,Current smoker: Includes daily and non-daily smokers,25,,10,23.5,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,1.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT3,pNx,cM0,Stage III,Not Evaluated,NO,N 30%%,SCC 75%,7772.142353,8589.873314,70.0,0.57517292,112,1,1.44584918655384,Immune,Mesenchymal +C3N-04278,71,Male,Poland,Current reformed smoker within past 15 years,30,68,15,28.5,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,4.0,Basaloid squamous cell carcinoma,G2 Moderately differentiated,Not identified,pT3,pNx,cM0,Stage III,Not Evaluated,NO,N 25%%,PD 70%,6713.95651,7074.622965,90.0,0.831636557,289,0,4.49836532312063,CIN,Classical +C3N-04279,65,Male,Poland,Current smoker: Includes daily and non-daily smokers,20,,15,33.8,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Floor of mouth,Oral cavity,Unifocal,3.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Not identified,pT2,pN0,cM0,Stage II,Not Evaluated,NO,N 20%%,PDCa 70%,4913.19811,5469.762929,20.0,0.862528998,183,0,5.76658394099771,Basal,Classical +C3N-04280,65,Male,Poland,Current reformed smoker within past 15 years,18,28,20,10.0,No or minimal exposure to secondhand smoke,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,4.0,"Squamous cell carcinoma, conventional",G1 Well differentiated,Not identified,pT2,pN0,cM0,Stage II,Not Evaluated,NO,,Veracan 80%,5615.887039,5361.231467,50.0,0.694324729,77,0,1.66514548259798,Basal,Basal +C3N-04611,55,Male,Ukraine,Current smoker: Includes daily and non-daily smokers,Unknown,,20,,Exposure to secondhand smoke history not available,strong_evidence,Alcohol consumption equal to or less than 2 drinks per day for men and 1 drink or less per day for women,,Larynx,Larynx,Unifocal,6.0,"Squamous cell carcinoma, conventional",G2 Moderately differentiated,Present,pT3,pNX,cM0,Stage III,Not Evaluated,NO,N 5%%,PDCa 70%;PDCa 70%;PDCa 80%,8445.538834,8745.826501,90.0,0.680310507,107,0,1.7013063766819,Immune,Mesenchymal diff --git a/examples/demo-ground-truth.ipynb b/examples/demo-ground-truth.ipynb new file mode 100644 index 00000000..626695b5 --- /dev/null +++ b/examples/demo-ground-truth.ipynb @@ -0,0 +1,3314 @@ 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\n", + "" + ] + }, + "metadata": { + "application/vnd.holoviews_exec.v0+json": { + "id": "3f8fdd9c-53b4-4204-9ce7-100e5a7d3b23" + } + }, + "output_type": "display_data" + } + ], + "source": [ + "import bdikit as bdi\n", + "import pandas as pd\n", + "from IPython.display import display, Markdown\n", + "pd.set_option('display.max_rows', None)" + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [], + "source": [ + "df_source = pd.read_csv(\"./datasets/Dou-ucec-discovery.csv\")\n", + "df_target = pd.read_csv(\"./datasets/Dou-ucec-confirmatory.csv\")\n", + "df_gt = pd.read_csv(\"./datasets/Dou-ucec-ground-truth.csv\")" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [], + "source": [ + "df_ground_truth = df_gt[~df_gt['target'].isna()]\n", + "gt_set = df_ground_truth.set_index('source')['target'].to_dict()" + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [], + "source": [ + "def accuracy(gt_set, schema_mapping):\n", + " schema_dict = schema_mapping.set_index('source')['target'].to_dict()\n", + " correct_count = 0\n", + " total = 0\n", + " for source_column, target_column in schema_dict.items():\n", + " if source_column in gt_set:\n", + " total += 1\n", + " correct_target_columns = set(gt_set[source_column].split(\",\"))\n", + " if target_column in correct_target_columns:\n", + " correct_count += 1\n", + " # print(f\"OK: {source_column} -> out={target_column} gt={correct_target_columns}\")\n", + " else:\n", + " print(f\"ER: {source_column} -> out={target_column} gt={correct_target_columns}\")\n", + " return correct_count/ float(total)" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": {}, + "outputs": [], + "source": [ + "df_source.columns = df_source.columns.str.replace(' ', '')" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Extracting features from 179 columns...\n" + ] + }, + { + "data": { + "application/vnd.jupyter.widget-view+json": { + "model_id": "8a055f6f3aac4175b83cda61c3bd7ea6", + "version_major": 2, + "version_minor": 0 + }, + "text/plain": [ + " 0%| | 0/179 [00:00 out=Idx gt={'Case_id'}\n", + "ER: Proteomics_TMT_batch -> out=Metformin_treatment gt={'Batch'}\n", + "ER: Proteomics_TMT_plex -> out=Number_of_para-aortic_lymph_nodes_positive_for_tumor_by_he gt={'Plex'}\n", + "ER: Proteomics_TMT_channel -> out=Number_of_para-aortic_lymph_nodes_positive_for_tumor_by_he gt={'ReporterName'}\n", + "ER: Treatment_naive -> out=Follow-up_additional_treatment_radiation_therapy_for_new_tumor gt={'Cancer_history_history_of_any_treatment'}\n", + "ER: Tumor_purity -> out=Tumor_necrosis gt={'ABSOLUTE_tumor_purity'}\n", + "ER: MSH6 -> out=Ancillary_studies_msh2 gt={'Ancillary_studies_msh6'}\n", + "ER: CIBERSORT_Monocytes -> out=Cibersort_Macrophage_M2 gt={'Cibersort_Monocyte'}\n", + "ER: CIBERSORT_Eosinophils -> out=xCell_Cancer_associated_fibroblast gt={'Cibersort_Eosinophil'}\n", + "ER: CIBERSORT_Neutrophils -> out=CNV_ratio gt={'Cibersort_Neutrophil'}\n", + "ER: ESTIMATE_ImmuneScore -> out=Estimate_ESTIMATEScore gt={'Estimate_ImmuneScore'}\n", + "Recall: 75.556\n" + ] + }, + { + "data": { + "text/html": [ + "
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sourcetarget
0idxxCell_T_cell_CD4+_Th1
1Proteomics_Participant_IDIdx
2Case_excludedCase_excluded
3Proteomics_TMT_batchMetformin_treatment
4Proteomics_TMT_plexNumber_of_para-aortic_lymph_nodes_positive_for...
5Proteomics_TMT_channelNumber_of_para-aortic_lymph_nodes_positive_for...
6Proteomics_Parent_Sample_IDsIdx
7Proteomics_Aliquot_IDAliquot_ID
8Proteomics_Tumor_NormalGroup
9Proteomics_OCTPOLE
10CountryParticipant_country
11Histologic_Grade_FIGOHistologic_grade
12Myometrial_invasion_SpecifyMyometrial_invasion_present_specify
13Histologic_typeHistologic_Type
14Treatment_naiveFollow-up_additional_treatment_radiation_thera...
15Tumor_purityTumor_necrosis
16Path_Stage_Primary_Tumor-pTPathologic_staging_primary_tumor_pt
17Path_Stage_Reg_Lymph_Nodes-pNPathologic_staging_regional_lymph_nodes_pn
18Clin_Stage_Dist_Mets-cMClinical_staging_distant_metastasis_cm
19Path_Stage_Dist_Mets-pMClinical_staging_distant_metastasis_cm
20tumor_Stage-PathologicalTumor_stage_pathological
21FIGO_stageTumor_stage_pathological
22LVSINumber_of_other_lymph_nodes_examined
23BMIBMI
24AgeAge
25DiabetesDiabetes
26RaceRace
27EthnicityEthnicity
28GenderSex
29Tumor_SiteTumor_site
30Tumor_Site_OtherTumor_site_other
31Tumor_FocalityTumor_focality
32Tumor_Size_cmTumor_size_cm
33Estrogen_ReceptorAncillary_studies_estrogen_receptor
34Estrogen_Receptor_%Ancillary_studies_estrogen_receptor
35Progesterone_ReceptorAncillary_studies_progesterone_receptor
36Progesterone_Receptor_%Ancillary_studies_progesterone_receptor
37MLH1Ancillary_studies_mlh1
38MLH2Ancillary_studies_mlh1
39MSH6Ancillary_studies_msh2
40PMS2Ancillary_studies_pms2
41p53Ancillary_studies_p53
42Other_IHC_specifyAncillary_studies_other_immunohistochemistry_t...
43MLH1_Promoter_HypermethylationAncillary_studies_mlh1_promoter_hypermethylation
44Num_full_term_pregnanciesDonor_information_number_of_full_term_pregnancies
45EPIC_BcellsProgeny_Androgen
46EPIC_CAFsCNV_ratio
47EPIC_CD4_TcellsAliquot_ID
48EPIC_CD8_TcellsxCell_T_cell_CD4+_Th2
49EPIC_EndothelialProgeny_Androgen
50EPIC_MacrophagesCibersort_Macrophage_M2
51EPIC_NKcellsxCell_NK_cell
52EPIC_otherCellsEstimate_ESTIMATEScore
53CIBERSORT_B_cells_naiveCibersort_T_cell_CD4+_memory_resting
54CIBERSORT_B_cells_memoryxCell_Cancer_associated_fibroblast
55CIBERSORT_Plasma_cellsProgeny_PI3K
56CIBERSORT_T_cells_CD8Cibersort_T_cell_CD4+_memory_resting
57CIBERSORT_T_cells_CD4_naiveCibersort_T_cell_CD4+_naive
58CIBERSORT_T_cells_CD4_memory_restingCNV_ratio
59CIBERSORT_T_cells_CD4_memory_activatedxCell_T_cell_CD4+_Th2
60CIBERSORT_T_cells_follicular_helperCibersort_T_cell_CD4+_memory_resting
61CIBERSORT_T_cells_regulatory_(Tregs)Cibersort_T_cell_CD4+_memory_resting
62CIBERSORT_T_cells_gamma_deltaxCell_T_cell_CD4+_Th2
63CIBERSORT_NK_cells_restingCibersort_NK_cell_activated
64CIBERSORT_NK_cells_activatedCibersort_NK_cell_activated
65CIBERSORT_MonocytesCibersort_Macrophage_M2
66CIBERSORT_Macrophages_M0Cibersort_Macrophage_M0
67CIBERSORT_Macrophages_M1Cibersort_Macrophage_M1
68CIBERSORT_Macrophages_M2Cibersort_Macrophage_M2
69CIBERSORT_Dendritic_cells_restingxCell_Cancer_associated_fibroblast
70CIBERSORT_Dendritic_cells_activatedCibersort_T_cell_CD4+_memory_resting
71CIBERSORT_Mast_cells_restingCibersort_Mast_cell_activated
72CIBERSORT_Mast_cells_activatedCibersort_Mast_cell_activated
73CIBERSORT_EosinophilsxCell_Cancer_associated_fibroblast
74CIBERSORT_NeutrophilsCNV_ratio
75CIBERSORT_Absolute_scoreCibersort_T_cell_follicular_helper
76ESTIMATE_StromalScoreEstimate_StromalScore
77ESTIMATE_ImmuneScoreEstimate_ESTIMATEScore
78ESTIMATE_ESTIMATEScoreEstimate_ESTIMATEScore
79Stemness_scoreProgeny_Androgen
80ER_ESR1xCell_stroma_score
81PR_PGRProgeny_EGFR
82Pathway_activity_EGFRAncillary_studies_progesterone_receptor
83Pathway_activity_HypoxiaxCell_immune_score
84Pathway_activity_JAK.STATMutation_signature_SBS5
85Pathway_activity_MAPKProgeny_MAPK
86Pathway_activity_NFkBPathologic_staging_regional_lymph_nodes_pn
87Pathway_activity_PI3KPathologic_staging_regional_lymph_nodes_pn
88Pathway_activity_TGFbABSOLUTE_tumor_purity
89Pathway_activity_TNFaPathologic_staging_primary_tumor_pt
90Pathway_activity_TrailPathologic_staging_primary_tumor_pt
91Pathway_activity_VEGFProgeny_VEGF
92Pathway_activity_p53Pathologic_staging_regional_lymph_nodes_pn
93TP53_ATMTP53
94TP53_CHEK2Ancillary_studies_pms2
95TP53_MDM4TP53
96TP53_RPS6KA3Ancillary_studies_pms2
97TP53_TP53TP53
98TP53_pathwayTP53
99PI3K_AKT1PIK3CA
100PI3K_AKT2PIK3CA
101PI3K_AKT3PIK3CA
102PI3K_DEPDC5PIK3CA
103PI3K_DEPTORPIK3CA
104PI3K_INPP4BPIK3CA
105PI3K_MAPKAP1PIK3CA
106PI3K_MLST8Ancillary_studies_pms2
107PI3K_MTORPIK3CA
108PI3K_NPRL2PIK3CA
109PI3K_NPRL3PIK3CA
110PI3K_PDK1PIK3CA
111PI3K_PIK3CAPIK3CA
112PI3K_PIK3CBPIK3CA
113PI3K_PIK3R1PIK3CA
114PI3K_PIK3R2PIK3CA
115PI3K_PPP2R1APIK3CA
116PI3K_PTENPIK3CA
117PI3K_RHEBPIK3CA
118PI3K_RICTORPIK3CA
119PI3K_RPS6PIK3CA
120PI3K_RPS6KB1PIK3CA
121PI3K_RPTORPIK3CA
122PI3K_STK11PIK3CA
123PI3K_TSC1PIK3CA
124PI3K_TSC2PIK3CA
125PI3K_pathwayPIK3CA
126HRD_BRCA1ARID1A
127HRD_BRCA2ARID1A
128HRD_BRCA1_or_BRCA2Batch
129CNV_DELCNV_ratio
130CNV_AMPCNV_ratio
131CNV_classCNV_status
132CNV_idxCNV_ratio
133CNV_1q_DELCNV_ratio
134CNV_3q_DELCNV_ratio
135CNV_4q_DELCNV_ratio
136CNV_1q_AMPCNV_ratio
137CNV_3q_AMPCNV_ratio
138CNV_4q_AMPCNV_ratio
139Purity_ImmuneProgeny_Androgen
140Purity_CancerProgeny_Hypoxia
141Purity_StromaProgeny_Androgen
142MSI_statusMSI_status
143POLE_subtypePOLE
144JAK1_MS_INDELMSI_status
145JAK1_MutationClinical_staging_distant_metastasis_cm
146Log2_variant_per_MbpProgeny_MAPK
147Log2_SNP_per_MbpProgeny_JAK.STAT
148Log2_INDEL_per_MbpCibersort_Macrophage_M0
149Log2_variant_totalEstimate_ESTIMATEScore
150Log2_SNP_totalCNV_ratio
151Log2_INDEL_totalEstimate_ESTIMATEScore
152Genomics_subtypeGenomic_subtype
153Mutation_signature_C>ACNV_ratio
154Mutation_signature_C>GCibersort_Macrophage_M2
155Mutation_signature_C>TEstimate_ImmuneScore
156Mutation_signature_T>CCibersort_Macrophage_M2
157Mutation_signature_T>AProgeny_Hypoxia
158Mutation_signature_T>GProgeny_TGFb
159WXS_normal_sample_typeAncillary_studies_other_immunohistochemistry_p...
160WXS_normal_filenameProgeny_WNT
161WXS_normal_UUIDProgeny_WNT
162WXS_tumor_sample_typeTumor_necrosis
163WXS_tumor_filenameProgeny_TGFb
164WXS_tumor_UUIDProgeny_WNT
165WGS_normal_sample_typeGroup
166WGS_normal_UUIDProgeny_WNT
167WGS_tumor_sample_typeTumor_site
168WGS_tumor_UUIDProgeny_TGFb
169RNAseq_R1_sample_typeARID1A
170RNAseq_R1_filenameAliquot_ID
171RNAseq_R1_UUIDAliquot_ID
172RNAseq_R2_sample_typeARID1A
173RNAseq_R2_filenameAliquot_ID
174RNAseq_R2_UUIDAliquot_ID
175miRNAseq_sample_typeMutation_signature_SBS7a
176miRNAseq_UUIDBatch
177Methylation_availableGroup
178Methylation_qualityMSI_status
\n", + "
" + ], + "text/plain": [ + " source \\\n", + "0 idx \n", + "1 Proteomics_Participant_ID \n", + "2 Case_excluded \n", + "3 Proteomics_TMT_batch \n", + "4 Proteomics_TMT_plex \n", + "5 Proteomics_TMT_channel \n", + "6 Proteomics_Parent_Sample_IDs \n", + "7 Proteomics_Aliquot_ID \n", + "8 Proteomics_Tumor_Normal \n", + "9 Proteomics_OCT \n", + "10 Country \n", + "11 Histologic_Grade_FIGO \n", + "12 Myometrial_invasion_Specify \n", + "13 Histologic_type \n", + "14 Treatment_naive \n", + "15 Tumor_purity \n", + "16 Path_Stage_Primary_Tumor-pT \n", + "17 Path_Stage_Reg_Lymph_Nodes-pN \n", + "18 Clin_Stage_Dist_Mets-cM \n", + "19 Path_Stage_Dist_Mets-pM \n", + "20 tumor_Stage-Pathological \n", + "21 FIGO_stage \n", + "22 LVSI \n", + "23 BMI \n", + "24 Age \n", + "25 Diabetes \n", + "26 Race \n", + "27 Ethnicity \n", + "28 Gender \n", + "29 Tumor_Site \n", + "30 Tumor_Site_Other \n", + "31 Tumor_Focality \n", + "32 Tumor_Size_cm \n", + "33 Estrogen_Receptor \n", + "34 Estrogen_Receptor_% \n", + "35 Progesterone_Receptor \n", + "36 Progesterone_Receptor_% \n", + "37 MLH1 \n", + "38 MLH2 \n", + "39 MSH6 \n", + "40 PMS2 \n", + "41 p53 \n", + "42 Other_IHC_specify \n", + "43 MLH1_Promoter_Hypermethylation \n", + "44 Num_full_term_pregnancies \n", + "45 EPIC_Bcells \n", + "46 EPIC_CAFs \n", + "47 EPIC_CD4_Tcells \n", + "48 EPIC_CD8_Tcells \n", + "49 EPIC_Endothelial \n", + "50 EPIC_Macrophages \n", + "51 EPIC_NKcells \n", + "52 EPIC_otherCells \n", + "53 CIBERSORT_B_cells_naive \n", + "54 CIBERSORT_B_cells_memory \n", + "55 CIBERSORT_Plasma_cells \n", + "56 CIBERSORT_T_cells_CD8 \n", + "57 CIBERSORT_T_cells_CD4_naive \n", + "58 CIBERSORT_T_cells_CD4_memory_resting \n", + "59 CIBERSORT_T_cells_CD4_memory_activated \n", + "60 CIBERSORT_T_cells_follicular_helper \n", + "61 CIBERSORT_T_cells_regulatory_(Tregs) \n", + "62 CIBERSORT_T_cells_gamma_delta \n", + "63 CIBERSORT_NK_cells_resting \n", + "64 CIBERSORT_NK_cells_activated \n", + "65 CIBERSORT_Monocytes \n", + "66 CIBERSORT_Macrophages_M0 \n", + "67 CIBERSORT_Macrophages_M1 \n", + "68 CIBERSORT_Macrophages_M2 \n", + "69 CIBERSORT_Dendritic_cells_resting \n", + "70 CIBERSORT_Dendritic_cells_activated \n", + "71 CIBERSORT_Mast_cells_resting \n", + "72 CIBERSORT_Mast_cells_activated \n", + "73 CIBERSORT_Eosinophils \n", + "74 CIBERSORT_Neutrophils \n", + "75 CIBERSORT_Absolute_score \n", + "76 ESTIMATE_StromalScore \n", + "77 ESTIMATE_ImmuneScore \n", + "78 ESTIMATE_ESTIMATEScore \n", + "79 Stemness_score \n", + "80 ER_ESR1 \n", + "81 PR_PGR \n", + "82 Pathway_activity_EGFR \n", + "83 Pathway_activity_Hypoxia \n", + "84 Pathway_activity_JAK.STAT \n", + "85 Pathway_activity_MAPK \n", + "86 Pathway_activity_NFkB \n", + "87 Pathway_activity_PI3K \n", + "88 Pathway_activity_TGFb \n", + "89 Pathway_activity_TNFa \n", + "90 Pathway_activity_Trail \n", + "91 Pathway_activity_VEGF \n", + "92 Pathway_activity_p53 \n", + "93 TP53_ATM \n", + "94 TP53_CHEK2 \n", + "95 TP53_MDM4 \n", + "96 TP53_RPS6KA3 \n", + "97 TP53_TP53 \n", + "98 TP53_pathway \n", + "99 PI3K_AKT1 \n", + "100 PI3K_AKT2 \n", + "101 PI3K_AKT3 \n", + "102 PI3K_DEPDC5 \n", + "103 PI3K_DEPTOR \n", + "104 PI3K_INPP4B \n", + "105 PI3K_MAPKAP1 \n", + "106 PI3K_MLST8 \n", + "107 PI3K_MTOR \n", + "108 PI3K_NPRL2 \n", + "109 PI3K_NPRL3 \n", + "110 PI3K_PDK1 \n", + "111 PI3K_PIK3CA \n", + "112 PI3K_PIK3CB \n", + "113 PI3K_PIK3R1 \n", + "114 PI3K_PIK3R2 \n", + "115 PI3K_PPP2R1A \n", + "116 PI3K_PTEN \n", + "117 PI3K_RHEB \n", + "118 PI3K_RICTOR \n", + "119 PI3K_RPS6 \n", + "120 PI3K_RPS6KB1 \n", + "121 PI3K_RPTOR \n", + "122 PI3K_STK11 \n", + "123 PI3K_TSC1 \n", + "124 PI3K_TSC2 \n", + "125 PI3K_pathway \n", + "126 HRD_BRCA1 \n", + "127 HRD_BRCA2 \n", + "128 HRD_BRCA1_or_BRCA2 \n", + "129 CNV_DEL \n", + "130 CNV_AMP \n", + "131 CNV_class \n", + "132 CNV_idx \n", + "133 CNV_1q_DEL \n", + "134 CNV_3q_DEL \n", + "135 CNV_4q_DEL \n", + "136 CNV_1q_AMP \n", + "137 CNV_3q_AMP \n", + "138 CNV_4q_AMP \n", + "139 Purity_Immune \n", + "140 Purity_Cancer \n", + "141 Purity_Stroma \n", + "142 MSI_status \n", + "143 POLE_subtype \n", + "144 JAK1_MS_INDEL \n", + "145 JAK1_Mutation \n", + "146 Log2_variant_per_Mbp \n", + "147 Log2_SNP_per_Mbp \n", + "148 Log2_INDEL_per_Mbp \n", + "149 Log2_variant_total \n", + "150 Log2_SNP_total \n", + "151 Log2_INDEL_total \n", + "152 Genomics_subtype \n", + "153 Mutation_signature_C>A \n", + "154 Mutation_signature_C>G \n", + "155 Mutation_signature_C>T \n", + "156 Mutation_signature_T>C \n", + "157 Mutation_signature_T>A \n", + "158 Mutation_signature_T>G \n", + "159 WXS_normal_sample_type \n", + "160 WXS_normal_filename \n", + "161 WXS_normal_UUID \n", + "162 WXS_tumor_sample_type \n", + "163 WXS_tumor_filename \n", + "164 WXS_tumor_UUID \n", + "165 WGS_normal_sample_type \n", + "166 WGS_normal_UUID \n", + "167 WGS_tumor_sample_type \n", + "168 WGS_tumor_UUID \n", + "169 RNAseq_R1_sample_type \n", + "170 RNAseq_R1_filename \n", + "171 RNAseq_R1_UUID \n", + "172 RNAseq_R2_sample_type \n", + "173 RNAseq_R2_filename \n", + "174 RNAseq_R2_UUID \n", + "175 miRNAseq_sample_type \n", + "176 miRNAseq_UUID \n", + "177 Methylation_available \n", + "178 Methylation_quality \n", + "\n", + " target \n", + "0 xCell_T_cell_CD4+_Th1 \n", + "1 Idx \n", + "2 Case_excluded \n", + "3 Metformin_treatment \n", + "4 Number_of_para-aortic_lymph_nodes_positive_for... \n", + "5 Number_of_para-aortic_lymph_nodes_positive_for... \n", + "6 Idx \n", + "7 Aliquot_ID \n", + "8 Group \n", + "9 POLE \n", + "10 Participant_country \n", + "11 Histologic_grade \n", + "12 Myometrial_invasion_present_specify \n", + "13 Histologic_Type \n", + "14 Follow-up_additional_treatment_radiation_thera... \n", + "15 Tumor_necrosis \n", + "16 Pathologic_staging_primary_tumor_pt \n", + "17 Pathologic_staging_regional_lymph_nodes_pn \n", + "18 Clinical_staging_distant_metastasis_cm \n", + "19 Clinical_staging_distant_metastasis_cm \n", + "20 Tumor_stage_pathological \n", + "21 Tumor_stage_pathological \n", + "22 Number_of_other_lymph_nodes_examined \n", + "23 BMI \n", + "24 Age \n", + "25 Diabetes \n", + "26 Race \n", + "27 Ethnicity \n", + "28 Sex \n", + "29 Tumor_site \n", + "30 Tumor_site_other \n", + "31 Tumor_focality \n", + "32 Tumor_size_cm \n", + "33 Ancillary_studies_estrogen_receptor \n", + "34 Ancillary_studies_estrogen_receptor \n", + "35 Ancillary_studies_progesterone_receptor \n", + "36 Ancillary_studies_progesterone_receptor \n", + "37 Ancillary_studies_mlh1 \n", + "38 Ancillary_studies_mlh1 \n", + "39 Ancillary_studies_msh2 \n", + "40 Ancillary_studies_pms2 \n", + "41 Ancillary_studies_p53 \n", + "42 Ancillary_studies_other_immunohistochemistry_t... \n", + "43 Ancillary_studies_mlh1_promoter_hypermethylation \n", + "44 Donor_information_number_of_full_term_pregnancies \n", + "45 Progeny_Androgen \n", + "46 CNV_ratio \n", + "47 Aliquot_ID \n", + "48 xCell_T_cell_CD4+_Th2 \n", + "49 Progeny_Androgen \n", + "50 Cibersort_Macrophage_M2 \n", + "51 xCell_NK_cell \n", + "52 Estimate_ESTIMATEScore \n", + "53 Cibersort_T_cell_CD4+_memory_resting \n", + "54 xCell_Cancer_associated_fibroblast \n", + "55 Progeny_PI3K \n", + "56 Cibersort_T_cell_CD4+_memory_resting \n", + "57 Cibersort_T_cell_CD4+_naive \n", + "58 CNV_ratio \n", + "59 xCell_T_cell_CD4+_Th2 \n", + "60 Cibersort_T_cell_CD4+_memory_resting \n", + "61 Cibersort_T_cell_CD4+_memory_resting \n", + "62 xCell_T_cell_CD4+_Th2 \n", + "63 Cibersort_NK_cell_activated \n", + "64 Cibersort_NK_cell_activated \n", + "65 Cibersort_Macrophage_M2 \n", + "66 Cibersort_Macrophage_M0 \n", + "67 Cibersort_Macrophage_M1 \n", + "68 Cibersort_Macrophage_M2 \n", + "69 xCell_Cancer_associated_fibroblast \n", + "70 Cibersort_T_cell_CD4+_memory_resting \n", + "71 Cibersort_Mast_cell_activated \n", + "72 Cibersort_Mast_cell_activated \n", + "73 xCell_Cancer_associated_fibroblast \n", + "74 CNV_ratio \n", + "75 Cibersort_T_cell_follicular_helper \n", + "76 Estimate_StromalScore \n", + "77 Estimate_ESTIMATEScore \n", + "78 Estimate_ESTIMATEScore \n", + "79 Progeny_Androgen \n", + "80 xCell_stroma_score \n", + "81 Progeny_EGFR \n", + "82 Ancillary_studies_progesterone_receptor \n", + "83 xCell_immune_score \n", + "84 Mutation_signature_SBS5 \n", + "85 Progeny_MAPK \n", + "86 Pathologic_staging_regional_lymph_nodes_pn \n", + "87 Pathologic_staging_regional_lymph_nodes_pn \n", + "88 ABSOLUTE_tumor_purity \n", + "89 Pathologic_staging_primary_tumor_pt \n", + "90 Pathologic_staging_primary_tumor_pt \n", + "91 Progeny_VEGF \n", + "92 Pathologic_staging_regional_lymph_nodes_pn \n", + "93 TP53 \n", + "94 Ancillary_studies_pms2 \n", + "95 TP53 \n", + "96 Ancillary_studies_pms2 \n", + "97 TP53 \n", + "98 TP53 \n", + "99 PIK3CA \n", + "100 PIK3CA \n", + "101 PIK3CA \n", + "102 PIK3CA \n", + "103 PIK3CA \n", + "104 PIK3CA \n", + "105 PIK3CA \n", + "106 Ancillary_studies_pms2 \n", + "107 PIK3CA \n", + "108 PIK3CA \n", + "109 PIK3CA \n", + "110 PIK3CA \n", + "111 PIK3CA \n", + "112 PIK3CA \n", + "113 PIK3CA \n", + "114 PIK3CA \n", + "115 PIK3CA \n", + "116 PIK3CA \n", + "117 PIK3CA \n", + "118 PIK3CA \n", + "119 PIK3CA \n", + "120 PIK3CA \n", + "121 PIK3CA \n", + "122 PIK3CA \n", + "123 PIK3CA \n", + "124 PIK3CA \n", + "125 PIK3CA \n", + "126 ARID1A \n", + "127 ARID1A \n", + "128 Batch \n", + "129 CNV_ratio \n", + "130 CNV_ratio \n", + "131 CNV_status \n", + "132 CNV_ratio \n", + "133 CNV_ratio \n", + "134 CNV_ratio \n", + "135 CNV_ratio \n", + "136 CNV_ratio \n", + "137 CNV_ratio \n", + "138 CNV_ratio \n", + "139 Progeny_Androgen \n", + "140 Progeny_Hypoxia \n", + "141 Progeny_Androgen \n", + "142 MSI_status \n", + "143 POLE \n", + "144 MSI_status \n", + "145 Clinical_staging_distant_metastasis_cm \n", + "146 Progeny_MAPK \n", + "147 Progeny_JAK.STAT \n", + "148 Cibersort_Macrophage_M0 \n", + "149 Estimate_ESTIMATEScore \n", + "150 CNV_ratio \n", + "151 Estimate_ESTIMATEScore \n", + "152 Genomic_subtype \n", + "153 CNV_ratio \n", + "154 Cibersort_Macrophage_M2 \n", + "155 Estimate_ImmuneScore \n", + "156 Cibersort_Macrophage_M2 \n", + "157 Progeny_Hypoxia \n", + "158 Progeny_TGFb \n", + "159 Ancillary_studies_other_immunohistochemistry_p... \n", + "160 Progeny_WNT \n", + "161 Progeny_WNT \n", + "162 Tumor_necrosis \n", + "163 Progeny_TGFb \n", + "164 Progeny_WNT \n", + "165 Group \n", + "166 Progeny_WNT \n", + "167 Tumor_site \n", + "168 Progeny_TGFb \n", + "169 ARID1A \n", + "170 Aliquot_ID \n", + "171 Aliquot_ID \n", + "172 ARID1A \n", + "173 Aliquot_ID \n", + "174 Aliquot_ID \n", + "175 Mutation_signature_SBS7a \n", + "176 Batch \n", + "177 Group \n", + "178 MSI_status " + ] + }, + "execution_count": 6, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "schema_mapping = bdi.match_schema(df_source, df_target, method='ct_learning')\n", + "print(f\"Recall: {100*accuracy(gt_set, schema_mapping):.3f}\")\n", + "schema_mapping" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Extracting features from 179 columns...\n" + ] + }, + { + "data": { + "application/vnd.jupyter.widget-view+json": { + "model_id": "fe32ed0bab28433ea1383cb720417793", + "version_major": 2, + "version_minor": 0 + }, + "text/plain": [ + " 0%| | 0/179 [00:00 out=Metformin_treatment gt={'Batch'}\n", + "ER: Proteomics_TMT_plex -> out=Number_of_para-aortic_lymph_nodes_positive_for_tumor_by_he gt={'Plex'}\n", + "ER: Treatment_naive -> out=Follow-up_additional_treatment_radiation_therapy_for_new_tumor gt={'Cancer_history_history_of_any_treatment'}\n", + "ER: Tumor_purity -> out=Tumor_necrosis gt={'ABSOLUTE_tumor_purity'}\n", + "ER: MSH6 -> out=Ancillary_studies_msh2 gt={'Ancillary_studies_msh6'}\n", + "ER: CIBERSORT_Monocytes -> out=Cibersort_Macrophage_M2 gt={'Cibersort_Monocyte'}\n", + "ER: CIBERSORT_Eosinophils -> out=xCell_Cancer_associated_fibroblast gt={'Cibersort_Eosinophil'}\n", + "ER: CIBERSORT_Neutrophils -> out=CNV_ratio gt={'Cibersort_Neutrophil'}\n", + "ER: ESTIMATE_ImmuneScore -> out=Estimate_ESTIMATEScore gt={'Estimate_ImmuneScore'}\n", + "Recall: 80.000\n" + ] + }, + { + "data": { + "text/html": [ + "
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sourcetarget
0idxNumber_of_para-aortic_lymph_nodes_examined
1Proteomics_Participant_IDCase_id
2Case_excludedCase_excluded
3Proteomics_TMT_batchMetformin_treatment
4Proteomics_TMT_plexNumber_of_para-aortic_lymph_nodes_positive_for...
5Proteomics_TMT_channelReporterName
6Proteomics_Parent_Sample_IDsCase_id
7Proteomics_Aliquot_IDAliquot_ID
8Proteomics_Tumor_NormalGroup
9Proteomics_OCTPOLE
10CountryParticipant_country
11Histologic_Grade_FIGOHistologic_grade
12Myometrial_invasion_SpecifyMyometrial_invasion_present_specify
13Histologic_typeHistologic_Type
14Treatment_naiveFollow-up_additional_treatment_radiation_thera...
15Tumor_purityTumor_necrosis
16Path_Stage_Primary_Tumor-pTPathologic_staging_primary_tumor_pt
17Path_Stage_Reg_Lymph_Nodes-pNPathologic_staging_regional_lymph_nodes_pn
18Clin_Stage_Dist_Mets-cMClinical_staging_distant_metastasis_cm
19Path_Stage_Dist_Mets-pMClinical_staging_distant_metastasis_cm
20tumor_Stage-PathologicalTumor_stage_pathological
21FIGO_stageTumor_stage_pathological
22LVSINumber_of_other_lymph_nodes_examined
23BMIBMI
24AgeAge
25DiabetesDiabetes
26RaceRace
27EthnicityEthnicity
28GenderSex
29Tumor_SiteTumor_site
30Tumor_Site_OtherTumor_site_other
31Tumor_FocalityTumor_focality
32Tumor_Size_cmTumor_size_cm
33Estrogen_ReceptorAncillary_studies_estrogen_receptor
34Estrogen_Receptor_%Ancillary_studies_estrogen_receptor
35Progesterone_ReceptorAncillary_studies_progesterone_receptor
36Progesterone_Receptor_%Ancillary_studies_progesterone_receptor
37MLH1Ancillary_studies_mlh1
38MLH2Ancillary_studies_mlh1
39MSH6Ancillary_studies_msh2
40PMS2Ancillary_studies_pms2
41p53Ancillary_studies_p53
42Other_IHC_specifyAncillary_studies_other_immunohistochemistry_t...
43MLH1_Promoter_HypermethylationAncillary_studies_mlh1_promoter_hypermethylation
44Num_full_term_pregnanciesDonor_information_number_of_full_term_pregnancies
45EPIC_BcellsProgeny_Androgen
46EPIC_CAFsCNV_ratio
47EPIC_CD4_TcellsAliquot_ID
48EPIC_CD8_TcellsxCell_T_cell_CD4+_Th2
49EPIC_EndothelialProgeny_Androgen
50EPIC_MacrophagesCibersort_Macrophage_M2
51EPIC_NKcellsxCell_NK_cell
52EPIC_otherCellsEstimate_ESTIMATEScore
53CIBERSORT_B_cells_naiveCibersort_T_cell_CD4+_memory_resting
54CIBERSORT_B_cells_memoryxCell_Cancer_associated_fibroblast
55CIBERSORT_Plasma_cellsProgeny_PI3K
56CIBERSORT_T_cells_CD8Cibersort_T_cell_CD4+_memory_resting
57CIBERSORT_T_cells_CD4_naiveCibersort_T_cell_CD4+_naive
58CIBERSORT_T_cells_CD4_memory_restingCNV_ratio
59CIBERSORT_T_cells_CD4_memory_activatedxCell_T_cell_CD4+_Th2
60CIBERSORT_T_cells_follicular_helperCibersort_T_cell_CD4+_memory_resting
61CIBERSORT_T_cells_regulatory_(Tregs)Cibersort_T_cell_CD4+_memory_resting
62CIBERSORT_T_cells_gamma_deltaxCell_T_cell_CD4+_Th2
63CIBERSORT_NK_cells_restingCibersort_NK_cell_activated
64CIBERSORT_NK_cells_activatedCibersort_NK_cell_activated
65CIBERSORT_MonocytesCibersort_Macrophage_M2
66CIBERSORT_Macrophages_M0Cibersort_Macrophage_M0
67CIBERSORT_Macrophages_M1Cibersort_Macrophage_M1
68CIBERSORT_Macrophages_M2Cibersort_Macrophage_M2
69CIBERSORT_Dendritic_cells_restingxCell_Cancer_associated_fibroblast
70CIBERSORT_Dendritic_cells_activatedCibersort_T_cell_CD4+_memory_resting
71CIBERSORT_Mast_cells_restingCibersort_Mast_cell_activated
72CIBERSORT_Mast_cells_activatedCibersort_Mast_cell_activated
73CIBERSORT_EosinophilsxCell_Cancer_associated_fibroblast
74CIBERSORT_NeutrophilsCNV_ratio
75CIBERSORT_Absolute_scoreCibersort_T_cell_follicular_helper
76ESTIMATE_StromalScoreEstimate_StromalScore
77ESTIMATE_ImmuneScoreEstimate_ESTIMATEScore
78ESTIMATE_ESTIMATEScoreEstimate_ESTIMATEScore
79Stemness_scoreProgeny_Androgen
80ER_ESR1xCell_stroma_score
81PR_PGRProgeny_EGFR
82Pathway_activity_EGFRAncillary_studies_progesterone_receptor
83Pathway_activity_HypoxiaxCell_immune_score
84Pathway_activity_JAK.STATMutation_signature_SBS5
85Pathway_activity_MAPKProgeny_MAPK
86Pathway_activity_NFkBPathologic_staging_regional_lymph_nodes_pn
87Pathway_activity_PI3KPathologic_staging_regional_lymph_nodes_pn
88Pathway_activity_TGFbABSOLUTE_tumor_purity
89Pathway_activity_TNFaPathologic_staging_primary_tumor_pt
90Pathway_activity_TrailPathologic_staging_primary_tumor_pt
91Pathway_activity_VEGFProgeny_VEGF
92Pathway_activity_p53Pathologic_staging_regional_lymph_nodes_pn
93TP53_ATMTP53
94TP53_CHEK2Ancillary_studies_pms2
95TP53_MDM4TP53
96TP53_RPS6KA3Ancillary_studies_pms2
97TP53_TP53TP53
98TP53_pathwayTP53
99PI3K_AKT1PIK3CA
100PI3K_AKT2PIK3CA
101PI3K_AKT3PIK3CA
102PI3K_DEPDC5PIK3CA
103PI3K_DEPTORPIK3CA
104PI3K_INPP4BPIK3CA
105PI3K_MAPKAP1PIK3CA
106PI3K_MLST8Ancillary_studies_pms2
107PI3K_MTORPIK3CA
108PI3K_NPRL2PIK3CA
109PI3K_NPRL3PIK3CA
110PI3K_PDK1PIK3CA
111PI3K_PIK3CAPIK3CA
112PI3K_PIK3CBPIK3CA
113PI3K_PIK3R1PIK3CA
114PI3K_PIK3R2PIK3CA
115PI3K_PPP2R1APIK3CA
116PI3K_PTENPIK3CA
117PI3K_RHEBPIK3CA
118PI3K_RICTORPIK3CA
119PI3K_RPS6PIK3CA
120PI3K_RPS6KB1PIK3CA
121PI3K_RPTORPIK3CA
122PI3K_STK11PIK3CA
123PI3K_TSC1PIK3CA
124PI3K_TSC2PIK3CA
125PI3K_pathwayPIK3CA
126HRD_BRCA1ARID1A
127HRD_BRCA2ARID1A
128HRD_BRCA1_or_BRCA2Batch
129CNV_DELCNV_ratio
130CNV_AMPCNV_ratio
131CNV_classCNV_status
132CNV_idxCNV_ratio
133CNV_1q_DELCNV_ratio
134CNV_3q_DELCNV_ratio
135CNV_4q_DELCNV_ratio
136CNV_1q_AMPCNV_ratio
137CNV_3q_AMPCNV_ratio
138CNV_4q_AMPCNV_ratio
139Purity_ImmuneProgeny_Androgen
140Purity_CancerProgeny_Hypoxia
141Purity_StromaProgeny_Androgen
142MSI_statusMSI_status
143POLE_subtypePOLE
144JAK1_MS_INDELMSI_status
145JAK1_MutationClinical_staging_distant_metastasis_cm
146Log2_variant_per_MbpProgeny_MAPK
147Log2_SNP_per_MbpProgeny_JAK.STAT
148Log2_INDEL_per_MbpCibersort_Macrophage_M0
149Log2_variant_totalEstimate_ESTIMATEScore
150Log2_SNP_totalCNV_ratio
151Log2_INDEL_totalEstimate_ESTIMATEScore
152Genomics_subtypeGenomic_subtype
153Mutation_signature_C>ACNV_ratio
154Mutation_signature_C>GCibersort_Macrophage_M2
155Mutation_signature_C>TEstimate_ImmuneScore
156Mutation_signature_T>CCibersort_Macrophage_M2
157Mutation_signature_T>AProgeny_Hypoxia
158Mutation_signature_T>GProgeny_TGFb
159WXS_normal_sample_typeAncillary_studies_other_immunohistochemistry_p...
160WXS_normal_filenameProgeny_WNT
161WXS_normal_UUIDProgeny_WNT
162WXS_tumor_sample_typeTumor_necrosis
163WXS_tumor_filenameProgeny_TGFb
164WXS_tumor_UUIDProgeny_WNT
165WGS_normal_sample_typeGroup
166WGS_normal_UUIDProgeny_WNT
167WGS_tumor_sample_typeTumor_site
168WGS_tumor_UUIDProgeny_TGFb
169RNAseq_R1_sample_typeARID1A
170RNAseq_R1_filenameAliquot_ID
171RNAseq_R1_UUIDAliquot_ID
172RNAseq_R2_sample_typeARID1A
173RNAseq_R2_filenameAliquot_ID
174RNAseq_R2_UUIDAliquot_ID
175miRNAseq_sample_typeMutation_signature_SBS7a
176miRNAseq_UUIDBatch
177Methylation_availableGroup
178Methylation_qualityMSI_status
\n", + "
" + ], + "text/plain": [ + " source \\\n", + "0 idx \n", + "1 Proteomics_Participant_ID \n", + "2 Case_excluded \n", + "3 Proteomics_TMT_batch \n", + "4 Proteomics_TMT_plex \n", + "5 Proteomics_TMT_channel \n", + "6 Proteomics_Parent_Sample_IDs \n", + "7 Proteomics_Aliquot_ID \n", + "8 Proteomics_Tumor_Normal \n", + "9 Proteomics_OCT \n", + "10 Country \n", + "11 Histologic_Grade_FIGO \n", + "12 Myometrial_invasion_Specify \n", + "13 Histologic_type \n", + "14 Treatment_naive \n", + "15 Tumor_purity \n", + "16 Path_Stage_Primary_Tumor-pT \n", + "17 Path_Stage_Reg_Lymph_Nodes-pN \n", + "18 Clin_Stage_Dist_Mets-cM \n", + "19 Path_Stage_Dist_Mets-pM \n", + "20 tumor_Stage-Pathological \n", + "21 FIGO_stage \n", + "22 LVSI \n", + "23 BMI \n", + "24 Age \n", + "25 Diabetes \n", + "26 Race \n", + "27 Ethnicity \n", + "28 Gender \n", + "29 Tumor_Site \n", + "30 Tumor_Site_Other \n", + "31 Tumor_Focality \n", + "32 Tumor_Size_cm \n", + "33 Estrogen_Receptor \n", + "34 Estrogen_Receptor_% \n", + "35 Progesterone_Receptor \n", + "36 Progesterone_Receptor_% \n", + "37 MLH1 \n", + "38 MLH2 \n", + "39 MSH6 \n", + "40 PMS2 \n", + "41 p53 \n", + "42 Other_IHC_specify \n", + "43 MLH1_Promoter_Hypermethylation \n", + "44 Num_full_term_pregnancies \n", + "45 EPIC_Bcells \n", + "46 EPIC_CAFs \n", + "47 EPIC_CD4_Tcells \n", + "48 EPIC_CD8_Tcells \n", + "49 EPIC_Endothelial \n", + "50 EPIC_Macrophages \n", + "51 EPIC_NKcells \n", + "52 EPIC_otherCells \n", + "53 CIBERSORT_B_cells_naive \n", + "54 CIBERSORT_B_cells_memory \n", + "55 CIBERSORT_Plasma_cells \n", + "56 CIBERSORT_T_cells_CD8 \n", + "57 CIBERSORT_T_cells_CD4_naive \n", + "58 CIBERSORT_T_cells_CD4_memory_resting \n", + "59 CIBERSORT_T_cells_CD4_memory_activated \n", + "60 CIBERSORT_T_cells_follicular_helper \n", + "61 CIBERSORT_T_cells_regulatory_(Tregs) \n", + "62 CIBERSORT_T_cells_gamma_delta \n", + "63 CIBERSORT_NK_cells_resting \n", + "64 CIBERSORT_NK_cells_activated \n", + "65 CIBERSORT_Monocytes \n", + "66 CIBERSORT_Macrophages_M0 \n", + "67 CIBERSORT_Macrophages_M1 \n", + "68 CIBERSORT_Macrophages_M2 \n", + "69 CIBERSORT_Dendritic_cells_resting \n", + "70 CIBERSORT_Dendritic_cells_activated \n", + "71 CIBERSORT_Mast_cells_resting \n", + "72 CIBERSORT_Mast_cells_activated \n", + "73 CIBERSORT_Eosinophils \n", + "74 CIBERSORT_Neutrophils \n", + "75 CIBERSORT_Absolute_score \n", + "76 ESTIMATE_StromalScore \n", + "77 ESTIMATE_ImmuneScore \n", + "78 ESTIMATE_ESTIMATEScore \n", + "79 Stemness_score \n", + "80 ER_ESR1 \n", + "81 PR_PGR \n", + "82 Pathway_activity_EGFR \n", + "83 Pathway_activity_Hypoxia \n", + "84 Pathway_activity_JAK.STAT \n", + "85 Pathway_activity_MAPK \n", + "86 Pathway_activity_NFkB \n", + "87 Pathway_activity_PI3K \n", + "88 Pathway_activity_TGFb \n", + "89 Pathway_activity_TNFa \n", + "90 Pathway_activity_Trail \n", + "91 Pathway_activity_VEGF \n", + "92 Pathway_activity_p53 \n", + "93 TP53_ATM \n", + "94 TP53_CHEK2 \n", + "95 TP53_MDM4 \n", + "96 TP53_RPS6KA3 \n", + "97 TP53_TP53 \n", + "98 TP53_pathway \n", + "99 PI3K_AKT1 \n", + "100 PI3K_AKT2 \n", + "101 PI3K_AKT3 \n", + "102 PI3K_DEPDC5 \n", + "103 PI3K_DEPTOR \n", + "104 PI3K_INPP4B \n", + "105 PI3K_MAPKAP1 \n", + "106 PI3K_MLST8 \n", + "107 PI3K_MTOR \n", + "108 PI3K_NPRL2 \n", + "109 PI3K_NPRL3 \n", + "110 PI3K_PDK1 \n", + "111 PI3K_PIK3CA \n", + "112 PI3K_PIK3CB \n", + "113 PI3K_PIK3R1 \n", + "114 PI3K_PIK3R2 \n", + "115 PI3K_PPP2R1A \n", + "116 PI3K_PTEN \n", + "117 PI3K_RHEB \n", + "118 PI3K_RICTOR \n", + "119 PI3K_RPS6 \n", + "120 PI3K_RPS6KB1 \n", + "121 PI3K_RPTOR \n", + "122 PI3K_STK11 \n", + "123 PI3K_TSC1 \n", + "124 PI3K_TSC2 \n", + "125 PI3K_pathway \n", + "126 HRD_BRCA1 \n", + "127 HRD_BRCA2 \n", + "128 HRD_BRCA1_or_BRCA2 \n", + "129 CNV_DEL \n", + "130 CNV_AMP \n", + "131 CNV_class \n", + "132 CNV_idx \n", + "133 CNV_1q_DEL \n", + "134 CNV_3q_DEL \n", + "135 CNV_4q_DEL \n", + "136 CNV_1q_AMP \n", + "137 CNV_3q_AMP \n", + "138 CNV_4q_AMP \n", + "139 Purity_Immune \n", + "140 Purity_Cancer \n", + "141 Purity_Stroma \n", + "142 MSI_status \n", + "143 POLE_subtype \n", + "144 JAK1_MS_INDEL \n", + "145 JAK1_Mutation \n", + "146 Log2_variant_per_Mbp \n", + "147 Log2_SNP_per_Mbp \n", + "148 Log2_INDEL_per_Mbp \n", + "149 Log2_variant_total \n", + "150 Log2_SNP_total \n", + "151 Log2_INDEL_total \n", + "152 Genomics_subtype \n", + "153 Mutation_signature_C>A \n", + "154 Mutation_signature_C>G \n", + "155 Mutation_signature_C>T \n", + "156 Mutation_signature_T>C \n", + "157 Mutation_signature_T>A \n", + "158 Mutation_signature_T>G \n", + "159 WXS_normal_sample_type \n", + "160 WXS_normal_filename \n", + "161 WXS_normal_UUID \n", + "162 WXS_tumor_sample_type \n", + "163 WXS_tumor_filename \n", + "164 WXS_tumor_UUID \n", + "165 WGS_normal_sample_type \n", + "166 WGS_normal_UUID \n", + "167 WGS_tumor_sample_type \n", + "168 WGS_tumor_UUID \n", + "169 RNAseq_R1_sample_type \n", + "170 RNAseq_R1_filename \n", + "171 RNAseq_R1_UUID \n", + "172 RNAseq_R2_sample_type \n", + "173 RNAseq_R2_filename \n", + "174 RNAseq_R2_UUID \n", + "175 miRNAseq_sample_type \n", + "176 miRNAseq_UUID \n", + "177 Methylation_available \n", + "178 Methylation_quality \n", + "\n", + " target \n", + "0 Number_of_para-aortic_lymph_nodes_examined \n", + "1 Case_id \n", + "2 Case_excluded \n", + "3 Metformin_treatment \n", + "4 Number_of_para-aortic_lymph_nodes_positive_for... \n", + "5 ReporterName \n", + "6 Case_id \n", + "7 Aliquot_ID \n", + "8 Group \n", + "9 POLE \n", + "10 Participant_country \n", + "11 Histologic_grade \n", + "12 Myometrial_invasion_present_specify \n", + "13 Histologic_Type \n", + "14 Follow-up_additional_treatment_radiation_thera... \n", + "15 Tumor_necrosis \n", + "16 Pathologic_staging_primary_tumor_pt \n", + "17 Pathologic_staging_regional_lymph_nodes_pn \n", + "18 Clinical_staging_distant_metastasis_cm \n", + "19 Clinical_staging_distant_metastasis_cm \n", + "20 Tumor_stage_pathological \n", + "21 Tumor_stage_pathological \n", + "22 Number_of_other_lymph_nodes_examined \n", + "23 BMI \n", + "24 Age \n", + "25 Diabetes \n", + "26 Race \n", + "27 Ethnicity \n", + "28 Sex \n", + "29 Tumor_site \n", + "30 Tumor_site_other \n", + "31 Tumor_focality \n", + "32 Tumor_size_cm \n", + "33 Ancillary_studies_estrogen_receptor \n", + "34 Ancillary_studies_estrogen_receptor \n", + "35 Ancillary_studies_progesterone_receptor \n", + "36 Ancillary_studies_progesterone_receptor \n", + "37 Ancillary_studies_mlh1 \n", + "38 Ancillary_studies_mlh1 \n", + "39 Ancillary_studies_msh2 \n", + "40 Ancillary_studies_pms2 \n", + "41 Ancillary_studies_p53 \n", + "42 Ancillary_studies_other_immunohistochemistry_t... \n", + "43 Ancillary_studies_mlh1_promoter_hypermethylation \n", + "44 Donor_information_number_of_full_term_pregnancies \n", + "45 Progeny_Androgen \n", + "46 CNV_ratio \n", + "47 Aliquot_ID \n", + "48 xCell_T_cell_CD4+_Th2 \n", + "49 Progeny_Androgen \n", + "50 Cibersort_Macrophage_M2 \n", + "51 xCell_NK_cell \n", + "52 Estimate_ESTIMATEScore \n", + "53 Cibersort_T_cell_CD4+_memory_resting \n", + "54 xCell_Cancer_associated_fibroblast \n", + "55 Progeny_PI3K \n", + "56 Cibersort_T_cell_CD4+_memory_resting \n", + "57 Cibersort_T_cell_CD4+_naive \n", + "58 CNV_ratio \n", + "59 xCell_T_cell_CD4+_Th2 \n", + "60 Cibersort_T_cell_CD4+_memory_resting \n", + "61 Cibersort_T_cell_CD4+_memory_resting \n", + "62 xCell_T_cell_CD4+_Th2 \n", + "63 Cibersort_NK_cell_activated \n", + "64 Cibersort_NK_cell_activated \n", + "65 Cibersort_Macrophage_M2 \n", + "66 Cibersort_Macrophage_M0 \n", + "67 Cibersort_Macrophage_M1 \n", + "68 Cibersort_Macrophage_M2 \n", + "69 xCell_Cancer_associated_fibroblast \n", + "70 Cibersort_T_cell_CD4+_memory_resting \n", + "71 Cibersort_Mast_cell_activated \n", + "72 Cibersort_Mast_cell_activated \n", + "73 xCell_Cancer_associated_fibroblast \n", + "74 CNV_ratio \n", + "75 Cibersort_T_cell_follicular_helper \n", + "76 Estimate_StromalScore \n", + "77 Estimate_ESTIMATEScore \n", + "78 Estimate_ESTIMATEScore \n", + "79 Progeny_Androgen \n", + "80 xCell_stroma_score \n", + "81 Progeny_EGFR \n", + "82 Ancillary_studies_progesterone_receptor \n", + "83 xCell_immune_score \n", + "84 Mutation_signature_SBS5 \n", + "85 Progeny_MAPK \n", + "86 Pathologic_staging_regional_lymph_nodes_pn \n", + "87 Pathologic_staging_regional_lymph_nodes_pn \n", + "88 ABSOLUTE_tumor_purity \n", + "89 Pathologic_staging_primary_tumor_pt \n", + "90 Pathologic_staging_primary_tumor_pt \n", + "91 Progeny_VEGF \n", + "92 Pathologic_staging_regional_lymph_nodes_pn \n", + "93 TP53 \n", + "94 Ancillary_studies_pms2 \n", + "95 TP53 \n", + "96 Ancillary_studies_pms2 \n", + "97 TP53 \n", + "98 TP53 \n", + "99 PIK3CA \n", + "100 PIK3CA \n", + "101 PIK3CA \n", + "102 PIK3CA \n", + "103 PIK3CA \n", + "104 PIK3CA \n", + "105 PIK3CA \n", + "106 Ancillary_studies_pms2 \n", + "107 PIK3CA \n", + "108 PIK3CA \n", + "109 PIK3CA \n", + "110 PIK3CA \n", + "111 PIK3CA \n", + "112 PIK3CA \n", + "113 PIK3CA \n", + "114 PIK3CA \n", + "115 PIK3CA \n", + "116 PIK3CA \n", + "117 PIK3CA \n", + "118 PIK3CA \n", + "119 PIK3CA \n", + "120 PIK3CA \n", + "121 PIK3CA \n", + "122 PIK3CA \n", + "123 PIK3CA \n", + "124 PIK3CA \n", + "125 PIK3CA \n", + "126 ARID1A \n", + "127 ARID1A \n", + "128 Batch \n", + "129 CNV_ratio \n", + "130 CNV_ratio \n", + "131 CNV_status \n", + "132 CNV_ratio \n", + "133 CNV_ratio \n", + "134 CNV_ratio \n", + "135 CNV_ratio \n", + "136 CNV_ratio \n", + "137 CNV_ratio \n", + "138 CNV_ratio \n", + "139 Progeny_Androgen \n", + "140 Progeny_Hypoxia \n", + "141 Progeny_Androgen \n", + "142 MSI_status \n", + "143 POLE \n", + "144 MSI_status \n", + "145 Clinical_staging_distant_metastasis_cm \n", + "146 Progeny_MAPK \n", + "147 Progeny_JAK.STAT \n", + "148 Cibersort_Macrophage_M0 \n", + "149 Estimate_ESTIMATEScore \n", + "150 CNV_ratio \n", + "151 Estimate_ESTIMATEScore \n", + "152 Genomic_subtype \n", + "153 CNV_ratio \n", + "154 Cibersort_Macrophage_M2 \n", + "155 Estimate_ImmuneScore \n", + "156 Cibersort_Macrophage_M2 \n", + "157 Progeny_Hypoxia \n", + "158 Progeny_TGFb \n", + "159 Ancillary_studies_other_immunohistochemistry_p... \n", + "160 Progeny_WNT \n", + "161 Progeny_WNT \n", + "162 Tumor_necrosis \n", + "163 Progeny_TGFb \n", + "164 Progeny_WNT \n", + "165 Group \n", + "166 Progeny_WNT \n", + "167 Tumor_site \n", + "168 Progeny_TGFb \n", + "169 ARID1A \n", + "170 Aliquot_ID \n", + "171 Aliquot_ID \n", + "172 ARID1A \n", + "173 Aliquot_ID \n", + "174 Aliquot_ID \n", + "175 Mutation_signature_SBS7a \n", + "176 Batch \n", + "177 Group \n", + "178 MSI_status " + ] + }, + "execution_count": 6, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "schema_mapping = bdi.match_schema(df_source, df_target, method='max_val_sim')\n", + "print(f\"Recall: {100*accuracy(gt_set, schema_mapping):.3f}\")\n", + "schema_mapping" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Extracting features from 1 columns...\n" + ] + }, + { + "data": { + "application/vnd.jupyter.widget-view+json": { + "model_id": "4a7415c43f464277a03431032c884d82", + "version_major": 2, + "version_minor": 0 + }, + "text/plain": [ + " 0%| | 0/1 [00:00\n", + "\n", + "\n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + "
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0Proteomics_Participant_IDIdx0.173261
1Proteomics_Participant_IDCase_id0.158389
2Proteomics_Participant_IDAliquot_ID0.123715
3Proteomics_Participant_IDxCell_T_cell_CD8+_central_memory0.103956
4Proteomics_Participant_IDProgeny_p530.102078
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" + ], + "text/plain": [ + "Empty DataFrame\n", + "Columns: [source, target, similarity]\n", + "Index: []" + ] + }, + "execution_count": 9, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.match_values(df_source, df_target, (\"TP53_TP53\", \"TP53\"), method='tfidf')" + ] + } + ], + "metadata": { + "kernelspec": { + "display_name": "venv", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.10.12" + } + }, + "nbformat": 4, + "nbformat_minor": 2 +} diff --git a/examples/demo-ucec.ipynb b/examples/demo-ucec.ipynb new file mode 100644 index 00000000..cff731c4 --- /dev/null +++ b/examples/demo-ucec.ipynb @@ -0,0 +1,7901 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# Getting Started\n", + "\n", + "## Data Harmonization with `bdikit`\n", + "\n", + "Data harmonization is the process of integrating and aligning data from different sources into a consistent format to ensure compatibility and interoperability across data analyses and systems. `bdikit` is a library the helps with key data harmonization steps:\n", + "- *Schema Mapping*: In this step, data from various sources are mapped to a unified schema or model. This involves identifying equivalent table columns and establishing relationships between disparate datasets.\n", + "- *Value Mapping (Data Standardization)*: This step involves converting data into a common format or structure, using consistent naming conventions, units, and coding systems to ensure uniformity.\n", + "\n", + "In this example, we describe how `bdikit` can be used to harmonize datasets from two papers:\n", + "- Dou et al. (https://pubmed.ncbi.nlm.nih.gov/37567170/)\n", + "- Cao et al (https://www.cell.com/cell/fulltext/S0092-8674(21)00997-1)." + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "#### Loading the data\n", + "\n", + "First, import the `bdikit` library and other libraries." + ] + }, + { + "cell_type": "code", + "execution_count": 1, + "metadata": {}, + "outputs": [], + "source": [ + "import bdikit as bdi\n", + "import pandas as pd\n", + "from IPython.display import display, Markdown" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Next, we load our source data using Pandas and select some columns we are interested in." + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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idxProteomics_Participant_IDCase_excludedProteomics_TMT_batchProteomics_TMT_plexProteomics_TMT_channelProteomics_Parent_Sample_IDsProteomics_Aliquot_IDProteomics_Tumor_NormalProteomics_OCT...RNAseq_R1_sample_typeRNAseq_R1_filenameRNAseq_R1_UUIDRNAseq_R2_sample_typeRNAseq_R2_filenameRNAseq_R2_UUIDmiRNAseq_sample_typemiRNAseq_UUIDMethylation_availableMethylation_quality
0S001C3L-00006No25128NC3L-00006-01CPT0001460012TumorNo...Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_TAGCTT_S17...8a1efc47-1c29-417f-a425-cdbd09565dcbTumor170802_UNC31-K00269_0072_AHK3GVBBXX_TAGCTT_S17...8c3fe9b7-7acd-4867-8d9c-a8e5d1516edaTumor37bcba98-1094-459e-83ae-c23a602416fbYESPASS
1S002C3L-00008No416130NC3L-00008-01CPT0001300009TumorNo...Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_GGCTAC_S22...555725e8-cba5-4676-9b0a-80100cbf9f47Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_GGCTAC_S22...15235b12-b67a-4678-acc4-ed03d642bd5eTumor492b50d8-ec35-46e7-a65d-06512aaee394YESPASS
2S003C3L-00032No12131C3L-00032-01CPT0001420009TumorNo...Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_GTCCGC_S18...9ae968f3-691d-4db3-9977-1ab3e5af9085Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_GTCCGC_S18...423b6b09-02aa-4f47-9241-f75c1dad1161Tumor1794ff56-db2d-4d1a-8758-cab7fe3d98c1YESPASS
3S004C3L-00084Yes311129NC3L-00084-01CPT0000820012TumorNo...Tumor170818_UNC32-K00270_0050_AHL2FHBBXX_ATCACG_S5_...b0a7cdf2-2ad8-4442-91b0-548ea4975554Tumor170818_UNC32-K00270_0050_AHL2FHBBXX_ATCACG_S5_...c83987a5-1c13-4af4-b46c-218fe5f60c34NaNNaNYESPASS
4S005C3L-00090No312129CC3L-00090-01CPT0001140003TumorNo...Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_GAGTGG_S10...8ce5618d-9ff6-40f9-aeea-8d8e1633ae38Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_GAGTGG_S10...06d3fd4a-a623-4146-8500-4f1f17235253Tumora6524c2d-d7dd-4629-980e-b45dbdc92c49YESPASS
5S006C3L-00098No414129NC3L-00098-02CPT0000980012TumorNo...Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_TTAGGC_S8_...31252ba9-e052-4b77-809a-f936379ae00cTumor170802_UNC31-K00269_0072_AHK3GVBBXX_TTAGGC_S8_...23be22ae-de50-4d74-a7c0-c890adbc662aNaNNaNYESPASS
6S007C3L-00136No416129CC3L-00136-03CPT0000730011TumorNo...Tumor170818_UNC32-K00270_0050_AHL2FHBBXX_GTCCGC_S10...df0e2942-c702-4135-81a0-fbec4439d753Tumor170818_UNC32-K00270_0050_AHL2FHBBXX_GTCCGC_S10...4e1ad404-4646-4828-91b9-e3c35a4ce505NaNNaNYESPASS
7S008C3L-00137No415130NC3L-00137-02CPT0002010011TumorNo...Tumor170818_UNC32-K00270_0050_AHL2FHBBXX_GTGAAA_S12...8fcdd6a1-a7c7-41b5-8b44-e41f2237b236Tumor170818_UNC32-K00270_0050_AHL2FHBBXX_GTGAAA_S12...2bea607d-6eb2-4583-90d7-7823a3d8a572NaNNaNYESPASS
8S009C3L-00139No311130NC3L-00139-01CPT0001850012TumorNo...Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_CAGATC_S1_...7785d5a1-a60d-41f9-86f3-e4ebc100704cTumor170802_UNC31-K00269_0072_AHK3GVBBXX_CAGATC_S1_...90ced367-0342-4739-93b2-4b1a4af800c4Tumora02b2784-9e7f-41b1-8e53-707ae4371c45YESPASS
9S010C3L-00143No414130CC3L-00143-01CPT0001910016TumorNo...Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_ACTTGA_S4_...6412838b-2f70-4b14-a6ee-3c7baca09fb0Tumor170802_UNC31-K00269_0072_AHK3GVBBXX_ACTTGA_S4_...5d0a26e0-2739-4f38-9350-c685b44911d3Tumor872be4b7-1735-48a6-a3a2-7541ec65ea87YESPASS
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10 rows × 179 columns

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" + ], + "text/plain": [ + " idx Proteomics_Participant_ID Case_excluded Proteomics_TMT_batch \\\n", + "0 S001 C3L-00006 No 2 \n", + "1 S002 C3L-00008 No 4 \n", + "2 S003 C3L-00032 No 1 \n", + "3 S004 C3L-00084 Yes 3 \n", + "4 S005 C3L-00090 No 3 \n", + "5 S006 C3L-00098 No 4 \n", + "6 S007 C3L-00136 No 4 \n", + "7 S008 C3L-00137 No 4 \n", + "8 S009 C3L-00139 No 3 \n", + "9 S010 C3L-00143 No 4 \n", + "\n", + " Proteomics_TMT_plex Proteomics_TMT_channel Proteomics_Parent_Sample_IDs \\\n", + "0 5 128N C3L-00006-01 \n", + "1 16 130N C3L-00008-01 \n", + "2 2 131 C3L-00032-01 \n", + "3 11 129N C3L-00084-01 \n", + "4 12 129C C3L-00090-01 \n", + "5 14 129N C3L-00098-02 \n", + "6 16 129C C3L-00136-03 \n", + "7 15 130N C3L-00137-02 \n", + "8 11 130N C3L-00139-01 \n", + "9 14 130C C3L-00143-01 \n", + "\n", + " Proteomics_Aliquot_ID Proteomics_Tumor_Normal Proteomics_OCT ... \\\n", + "0 CPT0001460012 Tumor No ... \n", + "1 CPT0001300009 Tumor No ... \n", + "2 CPT0001420009 Tumor No ... \n", + "3 CPT0000820012 Tumor No ... \n", + "4 CPT0001140003 Tumor No ... \n", + "5 CPT0000980012 Tumor No ... \n", + "6 CPT0000730011 Tumor No ... \n", + "7 CPT0002010011 Tumor No ... \n", + "8 CPT0001850012 Tumor No ... \n", + "9 CPT0001910016 Tumor No ... \n", + "\n", + " RNAseq_R1_sample_type RNAseq_R1_filename \\\n", + "0 Tumor 170802_UNC31-K00269_0072_AHK3GVBBXX_TAGCTT_S17... \n", + "1 Tumor 170802_UNC31-K00269_0072_AHK3GVBBXX_GGCTAC_S22... \n", + "2 Tumor 170802_UNC31-K00269_0072_AHK3GVBBXX_GTCCGC_S18... \n", + "3 Tumor 170818_UNC32-K00270_0050_AHL2FHBBXX_ATCACG_S5_... \n", + "4 Tumor 170802_UNC31-K00269_0072_AHK3GVBBXX_GAGTGG_S10... \n", + "5 Tumor 170802_UNC31-K00269_0072_AHK3GVBBXX_TTAGGC_S8_... \n", + "6 Tumor 170818_UNC32-K00270_0050_AHL2FHBBXX_GTCCGC_S10... \n", + "7 Tumor 170818_UNC32-K00270_0050_AHL2FHBBXX_GTGAAA_S12... \n", + "8 Tumor 170802_UNC31-K00269_0072_AHK3GVBBXX_CAGATC_S1_... \n", + "9 Tumor 170802_UNC31-K00269_0072_AHK3GVBBXX_ACTTGA_S4_... \n", + "\n", + " RNAseq_R1_UUID RNAseq_R2_sample_type \\\n", + "0 8a1efc47-1c29-417f-a425-cdbd09565dcb Tumor \n", + "1 555725e8-cba5-4676-9b0a-80100cbf9f47 Tumor \n", + "2 9ae968f3-691d-4db3-9977-1ab3e5af9085 Tumor \n", + "3 b0a7cdf2-2ad8-4442-91b0-548ea4975554 Tumor \n", + "4 8ce5618d-9ff6-40f9-aeea-8d8e1633ae38 Tumor \n", + "5 31252ba9-e052-4b77-809a-f936379ae00c Tumor \n", + "6 df0e2942-c702-4135-81a0-fbec4439d753 Tumor \n", + "7 8fcdd6a1-a7c7-41b5-8b44-e41f2237b236 Tumor \n", + "8 7785d5a1-a60d-41f9-86f3-e4ebc100704c Tumor \n", + "9 6412838b-2f70-4b14-a6ee-3c7baca09fb0 Tumor \n", + "\n", + " RNAseq_R2_filename \\\n", + "0 170802_UNC31-K00269_0072_AHK3GVBBXX_TAGCTT_S17... \n", + "1 170802_UNC31-K00269_0072_AHK3GVBBXX_GGCTAC_S22... \n", + "2 170802_UNC31-K00269_0072_AHK3GVBBXX_GTCCGC_S18... \n", + "3 170818_UNC32-K00270_0050_AHL2FHBBXX_ATCACG_S5_... \n", + "4 170802_UNC31-K00269_0072_AHK3GVBBXX_GAGTGG_S10... \n", + "5 170802_UNC31-K00269_0072_AHK3GVBBXX_TTAGGC_S8_... \n", + "6 170818_UNC32-K00270_0050_AHL2FHBBXX_GTCCGC_S10... \n", + "7 170818_UNC32-K00270_0050_AHL2FHBBXX_GTGAAA_S12... \n", + "8 170802_UNC31-K00269_0072_AHK3GVBBXX_CAGATC_S1_... \n", + "9 170802_UNC31-K00269_0072_AHK3GVBBXX_ACTTGA_S4_... \n", + "\n", + " RNAseq_R2_UUID miRNAseq_sample_type \\\n", + "0 8c3fe9b7-7acd-4867-8d9c-a8e5d1516eda Tumor \n", + "1 15235b12-b67a-4678-acc4-ed03d642bd5e Tumor \n", + "2 423b6b09-02aa-4f47-9241-f75c1dad1161 Tumor \n", + "3 c83987a5-1c13-4af4-b46c-218fe5f60c34 NaN \n", + "4 06d3fd4a-a623-4146-8500-4f1f17235253 Tumor \n", + "5 23be22ae-de50-4d74-a7c0-c890adbc662a NaN \n", + "6 4e1ad404-4646-4828-91b9-e3c35a4ce505 NaN \n", + "7 2bea607d-6eb2-4583-90d7-7823a3d8a572 NaN \n", + "8 90ced367-0342-4739-93b2-4b1a4af800c4 Tumor \n", + "9 5d0a26e0-2739-4f38-9350-c685b44911d3 Tumor \n", + "\n", + " miRNAseq_UUID Methylation_available \\\n", + "0 37bcba98-1094-459e-83ae-c23a602416fb YES \n", + "1 492b50d8-ec35-46e7-a65d-06512aaee394 YES \n", + "2 1794ff56-db2d-4d1a-8758-cab7fe3d98c1 YES \n", + "3 NaN YES \n", + "4 a6524c2d-d7dd-4629-980e-b45dbdc92c49 YES \n", + "5 NaN YES \n", + "6 NaN YES \n", + "7 NaN YES \n", + "8 a02b2784-9e7f-41b1-8e53-707ae4371c45 YES \n", + "9 872be4b7-1735-48a6-a3a2-7541ec65ea87 YES \n", + "\n", + " Methylation_quality \n", + "0 PASS \n", + "1 PASS \n", + "2 PASS \n", + "3 PASS \n", + "4 PASS \n", + "5 PASS \n", + "6 PASS \n", + "7 PASS \n", + "8 PASS \n", + "9 PASS \n", + "\n", + "[10 rows x 179 columns]" + ] + }, + "execution_count": 2, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "df_source = pd.read_csv(\"./datasets/Dou-ucec-discovery.csv\")\n", + "# column_names = [\n", + "# \"Country\",\n", + "# \"Gender\",\n", + "# \"FIGO_stage\",\n", + "# \"Path_Stage_Reg_Lymph_Nodes-pN\",\n", + "# \"tumor_Stage-Pathological\",\n", + "# \"Tumor_Focality\",\n", + "# ]\n", + "# df_source = df_source[column_names]\n", + "df_source.head(10)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Our goal is to harmonize the data from our source table (`dou.csv`) with the data from our target table `cao.csv`" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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IdxCase_idCase_excludedBatchPlexReporterNameAliquot_IDGroupDiscovery_studyAge...Follow-up_additional_surgery_for_new_tumorFollow-up_additional_treatment_radiation_therapy_for_new_tumorFollow-up_additional_treatment_pharmaceutical_therapy_for_new_tumorFollow-up_additional_treatment_immuno_for_new_tumorFollow-up_days_from_date_of_collection_to_date_of_last_contactFollow-up_cause_of_deathFollow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_deathFollow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_additional_surgery_for_new_tumorFollow-up_procedure_type_of_new_tumorFollow-up_residual_tumor_after_surgery_for_new_tumor
0C3L-00086C3L-00086Nob416.0128NCPT0092460003TumorNo56...n/a|No|No|No|Non/a|Yes|Yes|Yes|Yesn/a|Yes|Yes|Yes|Yesn/a|No|No|No|No330.0|701.0|1046.0|1436.0|n/an/a|n/a|n/a|n/a|Breast Carcinoman/a|n/a|n/a|n/a|1578.0n/a|n/a|n/a|n/a|n/an/a|n/a|n/a|n/a|n/an/a|n/a|n/a|n/a|n/a
1C3L-00898C3L-00898Nob414.0128CCPT0172200008TumorNo54...n/a|n/a|n/a|n/an/a|n/a|n/a|n/an/a|n/a|n/a|n/an/a|n/a|n/a|n/a396.0|746.0|982.0|1600.0n/a|n/a|n/a|n/an/a|n/a|n/a|n/an/a|n/a|n/a|n/an/a|n/a|n/a|n/an/a|n/a|n/a|n/a
2C3L-00943C3L-00943Nob415.0130CCPT0086090003TumorNo63...n/a|n/a|n/an/a|n/a|n/an/a|n/a|n/an/a|n/a|n/a237.0|693.0|1039.0n/a|n/a|n/an/a|n/a|n/an/a|n/a|n/an/a|n/a|n/an/a|n/a|n/a
3C3L-01064C3L-01064Nob39.0129NCPT0113430004TumorNo54...No|No|No|NoNo|Yes|No|NoYes|Yes|Yes|YesNo|No|No|No453.0|726.0|1062.0|1447.0n/a|n/a|n/a|n/an/a|n/a|n/a|n/an/a|n/a|n/a|n/an/a|n/a|n/a|n/an/a|n/a|n/a|n/a
4C3L-01277C3L-01277Nob413.0130NCPT0093170003TumorNo61...n/a|No|Non/a|No|Yesn/a|Yes|Non/a|No|No351.0|713.0|967.0n/a|n/a|n/an/a|n/a|n/an/a|n/a|n/an/a|n/a|n/an/a|n/a|n/a
\n", + "

5 rows × 213 columns

\n", + "
" + ], + "text/plain": [ + " Idx Case_id Case_excluded Batch Plex ReporterName Aliquot_ID \\\n", + "0 C3L-00086 C3L-00086 No b4 16.0 128N CPT0092460003 \n", + "1 C3L-00898 C3L-00898 No b4 14.0 128C CPT0172200008 \n", + "2 C3L-00943 C3L-00943 No b4 15.0 130C CPT0086090003 \n", + "3 C3L-01064 C3L-01064 No b3 9.0 129N CPT0113430004 \n", + "4 C3L-01277 C3L-01277 No b4 13.0 130N CPT0093170003 \n", + "\n", + " Group Discovery_study Age ... Follow-up_additional_surgery_for_new_tumor \\\n", + "0 Tumor No 56 ... n/a|No|No|No|No \n", + "1 Tumor No 54 ... n/a|n/a|n/a|n/a \n", + "2 Tumor No 63 ... n/a|n/a|n/a \n", + "3 Tumor No 54 ... No|No|No|No \n", + "4 Tumor No 61 ... n/a|No|No \n", + "\n", + " Follow-up_additional_treatment_radiation_therapy_for_new_tumor \\\n", + "0 n/a|Yes|Yes|Yes|Yes \n", + "1 n/a|n/a|n/a|n/a \n", + "2 n/a|n/a|n/a \n", + "3 No|Yes|No|No \n", + "4 n/a|No|Yes \n", + "\n", + " Follow-up_additional_treatment_pharmaceutical_therapy_for_new_tumor \\\n", + "0 n/a|Yes|Yes|Yes|Yes \n", + "1 n/a|n/a|n/a|n/a \n", + "2 n/a|n/a|n/a \n", + "3 Yes|Yes|Yes|Yes \n", + "4 n/a|Yes|No \n", + "\n", + " Follow-up_additional_treatment_immuno_for_new_tumor \\\n", + "0 n/a|No|No|No|No \n", + "1 n/a|n/a|n/a|n/a \n", + "2 n/a|n/a|n/a \n", + "3 No|No|No|No \n", + "4 n/a|No|No \n", + "\n", + " Follow-up_days_from_date_of_collection_to_date_of_last_contact \\\n", + "0 330.0|701.0|1046.0|1436.0|n/a \n", + "1 396.0|746.0|982.0|1600.0 \n", + "2 237.0|693.0|1039.0 \n", + "3 453.0|726.0|1062.0|1447.0 \n", + "4 351.0|713.0|967.0 \n", + "\n", + " Follow-up_cause_of_death \\\n", + "0 n/a|n/a|n/a|n/a|Breast Carcinoma \n", + "1 n/a|n/a|n/a|n/a \n", + "2 n/a|n/a|n/a \n", + "3 n/a|n/a|n/a|n/a \n", + "4 n/a|n/a|n/a \n", + "\n", + " Follow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_death \\\n", + "0 n/a|n/a|n/a|n/a|1578.0 \n", + "1 n/a|n/a|n/a|n/a \n", + "2 n/a|n/a|n/a \n", + "3 n/a|n/a|n/a|n/a \n", + "4 n/a|n/a|n/a \n", + "\n", + " Follow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_additional_surgery_for_new_tumor \\\n", + "0 n/a|n/a|n/a|n/a|n/a \n", + "1 n/a|n/a|n/a|n/a \n", + "2 n/a|n/a|n/a \n", + "3 n/a|n/a|n/a|n/a \n", + "4 n/a|n/a|n/a \n", + "\n", + " Follow-up_procedure_type_of_new_tumor \\\n", + "0 n/a|n/a|n/a|n/a|n/a \n", + "1 n/a|n/a|n/a|n/a \n", + "2 n/a|n/a|n/a \n", + "3 n/a|n/a|n/a|n/a \n", + "4 n/a|n/a|n/a \n", + "\n", + " Follow-up_residual_tumor_after_surgery_for_new_tumor \n", + "0 n/a|n/a|n/a|n/a|n/a \n", + "1 n/a|n/a|n/a|n/a \n", + "2 n/a|n/a|n/a \n", + "3 n/a|n/a|n/a|n/a \n", + "4 n/a|n/a|n/a \n", + "\n", + "[5 rows x 213 columns]" + ] + }, + "execution_count": 3, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "df_target = pd.read_csv(\"./datasets/Dou-ucec-confirmatory.csv\")\n", + "df_target.head(5)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "#### Finding column matches between two tables\n", + "\n", + "`bdi-kit` offers a suite of functions to help with data harmonization tasks.\n", + "\n", + "For instance, it can help automatically discover one-to-one mappings between the source and target dataset columns.\n", + "\n", + "To do so using `bdi-kit`, we can use the `match_schema()` function to match columns of the two schemas as follows." + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Extracting features from 179 columns...\n" + ] + }, + { + "data": { + "application/vnd.jupyter.widget-view+json": { + "model_id": "fa1a83a2181547f49d962d9750c579ac", + "version_major": 2, + "version_minor": 0 + }, + "text/plain": [ + " 0%| | 0/179 [00:00\n", + "\n", + "\n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + "
sourcetarget
0idxxCell_T_cell_CD4+_Th1
1Proteomics_Participant_IDIdx
2Case_excludedCase_excluded
3Proteomics_TMT_batchABSOLUTE_tumor_purity
4Proteomics_TMT_plexNumber_of_para-aortic_lymph_nodes_examined
.........
174RNAseq_R2_UUIDCase_id
175miRNAseq_sample_typeMutation_signature_SBS7a
176miRNAseq_UUIDCase_id
177Methylation_availableMutation_signature_SBS42
178Methylation_qualityMSI_status
\n", + "

179 rows × 2 columns

\n", + "" + ], + "text/plain": [ + " source target\n", + "0 idx xCell_T_cell_CD4+_Th1\n", + "1 Proteomics_Participant_ID Idx\n", + "2 Case_excluded Case_excluded\n", + "3 Proteomics_TMT_batch ABSOLUTE_tumor_purity\n", + "4 Proteomics_TMT_plex Number_of_para-aortic_lymph_nodes_examined\n", + ".. ... ...\n", + "174 RNAseq_R2_UUID Case_id\n", + "175 miRNAseq_sample_type Mutation_signature_SBS7a\n", + "176 miRNAseq_UUID Case_id\n", + "177 Methylation_available Mutation_signature_SBS42\n", + "178 Methylation_quality MSI_status\n", + "\n", + "[179 rows x 2 columns]" + ] + }, + "execution_count": 4, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.match_schema(df_source, df_target, method=\"ct_learning\")" + ] + }, + { + "cell_type": "code", + "execution_count": 9, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Extracting features from 179 columns...\n" + ] + }, + { + "data": { + 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sourcetarget
0idxxCell_T_cell_CD4+_Th1
1Proteomics_Participant_IDIdx
2Case_excludedCase_excluded
3Proteomics_TMT_batchABSOLUTE_tumor_purity
4Proteomics_TMT_plexNumber_of_para-aortic_lymph_nodes_examined
5Proteomics_TMT_channelReporterName
6Proteomics_Parent_Sample_IDsIdx
7Proteomics_Aliquot_IDAliquot_ID
8Proteomics_Tumor_NormalGroup
9Proteomics_OCTPOLE
10CountryParticipant_country
11Histologic_Grade_FIGOHistologic_grade
12Myometrial_invasion_SpecifyMyometrial_invasion_present_specify
13Histologic_typeHistologic_Type
14Treatment_naiveFollow-up_additional_treatment_radiation_thera...
15Tumor_purityTumor_necrosis
16Path_Stage_Primary_Tumor-pTPathologic_staging_primary_tumor_pt
17Path_Stage_Reg_Lymph_Nodes-pNPathologic_staging_regional_lymph_nodes_pn
18Clin_Stage_Dist_Mets-cMClinical_staging_distant_metastasis_cm
19Path_Stage_Dist_Mets-pMClinical_staging_distant_metastasis_cm
20tumor_Stage-PathologicalTumor_stage_pathological
21FIGO_stagePathologic_staging_primary_tumor_pt
22LVSINumber_of_pelvic_lymph_nodes_examined
23BMIBMI
24AgeAge
25DiabetesDiabetes
26RaceRace
27EthnicityEthnicity
28GenderSex
29Tumor_SiteTumor_site
30Tumor_Site_OtherTumor_site_other
31Tumor_FocalityTumor_focality
32Tumor_Size_cmTumor_size_cm
33Estrogen_ReceptorAncillary_studies_estrogen_receptor
34Estrogen_Receptor_%Ancillary_studies_estrogen_receptor
35Progesterone_ReceptorAncillary_studies_progesterone_receptor
36Progesterone_Receptor_%Ancillary_studies_progesterone_receptor
37MLH1Ancillary_studies_mlh1
38MLH2Ancillary_studies_mlh1
39MSH6Ancillary_studies_msh2
40PMS2Ancillary_studies_pms2
41p53Ancillary_studies_p53
42Other_IHC_specifyAncillary_studies_other_immunohistochemistry_t...
43MLH1_Promoter_HypermethylationAncillary_studies_mlh1_promoter_hypermethylation
44Num_full_term_pregnanciesDonor_information_number_of_full_term_pregnancies
45EPIC_BcellsProgeny_JAK.STAT
46EPIC_CAFsAliquot_ID
47EPIC_CD4_TcellsAliquot_ID
48EPIC_CD8_TcellsxCell_T_cell_CD4+_Th2
49EPIC_EndothelialProgeny_PI3K
50EPIC_MacrophagesCibersort_Macrophage_M2
51EPIC_NKcellsxCell_NK_cell
52EPIC_otherCellsxCell_Cancer_associated_fibroblast
53CIBERSORT_B _cells _naivexCell_Cancer_associated_fibroblast
54CIBERSORT_B _cells _memoryxCell_Cancer_associated_fibroblast
55CIBERSORT_Plasma _cellsProgeny_PI3K
56CIBERSORT_T _cells _CD8xCell_T_cell_CD4+_Th2
57CIBERSORT_T _cells _CD4 _naiveCibersort_T_cell_CD4+_naive
58CIBERSORT_T _cells _CD4 _memory _restingCNV_ratio
59CIBERSORT_T _cells _CD4 _memory _activatedxCell_T_cell_CD4+_Th2
60CIBERSORT_T _cells _follicular _helperxCell_Cancer_associated_fibroblast
61CIBERSORT_T _cells _regulatory _(Tregs)Progeny_TGFb
62CIBERSORT_T _cells _gamma _deltaProgeny_TGFb
63CIBERSORT_NK _cells _restingCibersort_NK_cell_activated
64CIBERSORT_NK _cells _activatedCibersort_NK_cell_activated
65CIBERSORT_MonocytesCibersort_Macrophage_M2
66CIBERSORT_Macrophages _M0Cibersort_Macrophage_M0
67CIBERSORT_Macrophages _M1Cibersort_Macrophage_M0
68CIBERSORT_Macrophages _M2Cibersort_Macrophage_M2
69CIBERSORT_Dendritic _cells _restingxCell_Cancer_associated_fibroblast
70CIBERSORT_Dendritic _cells _activatedxCell_Cancer_associated_fibroblast
71CIBERSORT_Mast _cells _restingCibersort_Mast_cell_activated
72CIBERSORT_Mast _cells _activatedCibersort_Mast_cell_activated
73CIBERSORT_EosinophilsxCell_Cancer_associated_fibroblast
74CIBERSORT_NeutrophilsCNV_ratio
75CIBERSORT_Absolute _scoreCibersort_T_cell_follicular_helper
76ESTIMATE_StromalScoreEstimate_StromalScore
77ESTIMATE_ImmuneScoreEstimate_ESTIMATEScore
78ESTIMATE_ESTIMATEScoreEstimate_ESTIMATEScore
79Stemness_scoreProgeny_Androgen
80ER_ESR1xCell_stroma_score
81PR_PGRProgeny_Trail
82Pathway_activity_EGFRProgeny_Trail
83Pathway_activity_HypoxiaxCell_stroma_score
84Pathway_activity_JAK.STATMutation_signature_SBS1
85Pathway_activity_MAPKBMI
86Pathway_activity_NFkBProgeny_NFkB
87Pathway_activity_PI3KPathologic_staging_regional_lymph_nodes_pn
88Pathway_activity_TGFbABSOLUTE_tumor_purity
89Pathway_activity_TNFaPathologic_staging_primary_tumor_pt
90Pathway_activity_TrailPathologic_staging_primary_tumor_pt
91Pathway_activity_VEGFProgeny_VEGF
92Pathway_activity_p53xCell_stroma_score
93TP53_ATMTP53
94TP53_CHEK2Cibersort_T_cell_CD4+_naive
95TP53_MDM4TP53
96TP53_RPS6KA3Ancillary_studies_pms2
97TP53_TP53TP53
98TP53_pathwayTP53
99PI3K_AKT1PIK3CA
100PI3K_AKT2PIK3CA
101PI3K_AKT3PIK3CA
102PI3K_DEPDC5PIK3CA
103PI3K_DEPTORPIK3CA
104PI3K_INPP4BPIK3CA
105PI3K_MAPKAP1PIK3CA
106PI3K_MLST8PIK3CA
107PI3K_MTORPIK3CA
108PI3K_NPRL2PIK3CA
109PI3K_NPRL3PIK3CA
110PI3K_PDK1PIK3CA
111PI3K_PIK3CAPIK3CA
112PI3K_PIK3CBPIK3CA
113PI3K_PIK3R1PIK3CA
114PI3K_PIK3R2PIK3CA
115PI3K_PPP2R1APIK3CA
116PI3K_PTENPIK3CA
117PI3K_RHEBPIK3CA
118PI3K_RICTORPIK3CA
119PI3K_RPS6PIK3CA
120PI3K_RPS6KB1PIK3CA
121PI3K_RPTORPIK3CA
122PI3K_STK11PIK3CA
123PI3K_TSC1PIK3CA
124PI3K_TSC2PIK3CA
125PI3K_pathwayPIK3CA
126HRD_BRCA1Batch
127HRD_BRCA2Batch
128HRD_BRCA1_or_BRCA2Batch
129CNV_DELCNV_ratio
130CNV_AMPCNV_ratio
131CNV_classCNV_status
132CNV_idxCNV_ratio
133CNV_1q_DELCNV_ratio
134CNV_3q_DELIdx
135CNV_4q_DELCNV_ratio
136CNV_1q_AMPCNV_ratio
137CNV_3q_AMPCNV_ratio
138CNV_4q_AMPCNV_ratio
139Purity_ImmuneProgeny_Androgen
140Purity_CancerProgeny_Androgen
141Purity_StromaProgeny_Androgen
142MSI_statusMSI_status
143POLE_subtypePOLE
144JAK1_MS_INDELMSI_status
145JAK1_MutationBMI
146Log2_variant_per_MbpProgeny_MAPK
147Log2_SNP_per_MbpProgeny_JAK.STAT
148Log2_INDEL_per_MbpCibersort_Macrophage_M0
149Log2_variant_totalEstimate_ESTIMATEScore
150Log2_SNP_totalCNV_ratio
151Log2_INDEL_totalEstimate_ESTIMATEScore
152Genomics_subtypeGenomic_subtype
153Mutation_signature_C>ACNV_ratio
154Mutation_signature_C>GCibersort_Macrophage_M2
155Mutation_signature_C>TxCell_Cancer_associated_fibroblast
156Mutation_signature_T>CCibersort_Macrophage_M2
157Mutation_signature_T>AProgeny_Hypoxia
158Mutation_signature_T>GProgeny_TGFb
159WXS_normal_sample_typeBatch
160WXS_normal_filenameProgeny_WNT
161WXS_normal_UUIDCase_id
162WXS_tumor_sample_typeTumor_site
163WXS_tumor_filenameProgeny_TGFb
164WXS_tumor_UUIDProgeny_TGFb
165WGS_normal_sample_typeMutation_signature_SBS7a
166WGS_normal_UUIDCase_id
167WGS_tumor_sample_typeTumor_site
168WGS_tumor_UUIDProgeny_TGFb
169RNAseq_R1_sample_typeARID1A
170RNAseq_R1_filenameAliquot_ID
171RNAseq_R1_UUIDCase_id
172RNAseq_R2_sample_typeARID1A
173RNAseq_R2_filenameAliquot_ID
174RNAseq_R2_UUIDCase_id
175miRNAseq_sample_typeMutation_signature_SBS7a
176miRNAseq_UUIDCase_id
177Methylation_availableMutation_signature_SBS42
178Methylation_qualityMSI_status
\n", + "" + ], + "text/plain": [ + " source \\\n", + "0 idx \n", + "1 Proteomics_Participant_ID \n", + "2 Case_excluded \n", + "3 Proteomics_TMT_batch \n", + "4 Proteomics_TMT_plex \n", + "5 Proteomics_TMT_channel \n", + "6 Proteomics_Parent_Sample_IDs \n", + "7 Proteomics_Aliquot_ID \n", + "8 Proteomics_Tumor_Normal \n", + "9 Proteomics_OCT \n", + "10 Country \n", + "11 Histologic_Grade_FIGO \n", + "12 Myometrial_invasion_Specify \n", + "13 Histologic_type \n", + "14 Treatment_naive \n", + "15 Tumor_purity \n", + "16 Path_Stage_Primary_Tumor-pT \n", + "17 Path_Stage_Reg_Lymph_Nodes-pN \n", + "18 Clin_Stage_Dist_Mets-cM \n", + "19 Path_Stage_Dist_Mets-pM \n", + "20 tumor_Stage-Pathological \n", + "21 FIGO_stage \n", + "22 LVSI \n", + "23 BMI \n", + "24 Age \n", + "25 Diabetes \n", + "26 Race \n", + "27 Ethnicity \n", + "28 Gender \n", + "29 Tumor_Site \n", + "30 Tumor_Site_Other \n", + "31 Tumor_Focality \n", + "32 Tumor_Size_cm \n", + "33 Estrogen_Receptor \n", + "34 Estrogen_Receptor_% \n", + "35 Progesterone_Receptor \n", + "36 Progesterone_Receptor_% \n", + "37 MLH1 \n", + "38 MLH2 \n", + "39 MSH6 \n", + "40 PMS2 \n", + "41 p53 \n", + "42 Other_IHC_specify \n", + "43 MLH1_Promoter_Hypermethylation \n", + "44 Num_full_term_pregnancies \n", + "45 EPIC_Bcells \n", + "46 EPIC_CAFs \n", + "47 EPIC_CD4_Tcells \n", + "48 EPIC_CD8_Tcells \n", + "49 EPIC_Endothelial \n", + "50 EPIC_Macrophages \n", + "51 EPIC_NKcells \n", + "52 EPIC_otherCells \n", + "53 CIBERSORT_B _cells _naive \n", + "54 CIBERSORT_B _cells _memory \n", + "55 CIBERSORT_Plasma _cells \n", + "56 CIBERSORT_T _cells _CD8 \n", + "57 CIBERSORT_T _cells _CD4 _naive \n", + "58 CIBERSORT_T _cells _CD4 _memory _resting \n", + "59 CIBERSORT_T _cells _CD4 _memory _activated \n", + "60 CIBERSORT_T _cells _follicular _helper \n", + "61 CIBERSORT_T _cells _regulatory _(Tregs) \n", + "62 CIBERSORT_T _cells _gamma _delta \n", + "63 CIBERSORT_NK _cells _resting \n", + "64 CIBERSORT_NK _cells _activated \n", + "65 CIBERSORT_Monocytes \n", + "66 CIBERSORT_Macrophages _M0 \n", + "67 CIBERSORT_Macrophages _M1 \n", + "68 CIBERSORT_Macrophages _M2 \n", + "69 CIBERSORT_Dendritic _cells _resting \n", + "70 CIBERSORT_Dendritic _cells _activated \n", + "71 CIBERSORT_Mast _cells _resting \n", + "72 CIBERSORT_Mast _cells _activated \n", + "73 CIBERSORT_Eosinophils \n", + "74 CIBERSORT_Neutrophils \n", + "75 CIBERSORT_Absolute _score \n", + "76 ESTIMATE_StromalScore \n", + "77 ESTIMATE_ImmuneScore \n", + "78 ESTIMATE_ESTIMATEScore \n", + "79 Stemness_score \n", + "80 ER_ESR1 \n", + "81 PR_PGR \n", + "82 Pathway_activity_EGFR \n", + "83 Pathway_activity_Hypoxia \n", + "84 Pathway_activity_JAK.STAT \n", + "85 Pathway_activity_MAPK \n", + "86 Pathway_activity_NFkB \n", + "87 Pathway_activity_PI3K \n", + "88 Pathway_activity_TGFb \n", + "89 Pathway_activity_TNFa \n", + "90 Pathway_activity_Trail \n", + "91 Pathway_activity_VEGF \n", + "92 Pathway_activity_p53 \n", + "93 TP53_ATM \n", + "94 TP53_CHEK2 \n", + "95 TP53_MDM4 \n", + "96 TP53_RPS6KA3 \n", + "97 TP53_TP53 \n", + "98 TP53_pathway \n", + "99 PI3K_AKT1 \n", + "100 PI3K_AKT2 \n", + "101 PI3K_AKT3 \n", + "102 PI3K_DEPDC5 \n", + "103 PI3K_DEPTOR \n", + "104 PI3K_INPP4B \n", + "105 PI3K_MAPKAP1 \n", + "106 PI3K_MLST8 \n", + "107 PI3K_MTOR \n", + "108 PI3K_NPRL2 \n", + "109 PI3K_NPRL3 \n", + "110 PI3K_PDK1 \n", + "111 PI3K_PIK3CA \n", + "112 PI3K_PIK3CB \n", + "113 PI3K_PIK3R1 \n", + "114 PI3K_PIK3R2 \n", + "115 PI3K_PPP2R1A \n", + "116 PI3K_PTEN \n", + "117 PI3K_RHEB \n", + "118 PI3K_RICTOR \n", + "119 PI3K_RPS6 \n", + "120 PI3K_RPS6KB1 \n", + "121 PI3K_RPTOR \n", + "122 PI3K_STK11 \n", + "123 PI3K_TSC1 \n", + "124 PI3K_TSC2 \n", + "125 PI3K_pathway \n", + "126 HRD_BRCA1 \n", + "127 HRD_BRCA2 \n", + "128 HRD_BRCA1_or_BRCA2 \n", + "129 CNV_DEL \n", + "130 CNV_AMP \n", + "131 CNV_class \n", + "132 CNV_idx \n", + "133 CNV_1q_DEL \n", + "134 CNV_3q_DEL \n", + "135 CNV_4q_DEL \n", + "136 CNV_1q_AMP \n", + "137 CNV_3q_AMP \n", + "138 CNV_4q_AMP \n", + "139 Purity_Immune \n", + "140 Purity_Cancer \n", + "141 Purity_Stroma \n", + "142 MSI_status \n", + "143 POLE_subtype \n", + "144 JAK1_MS_INDEL \n", + "145 JAK1_Mutation \n", + "146 Log2_variant_per_Mbp \n", + "147 Log2_SNP_per_Mbp \n", + "148 Log2_INDEL_per_Mbp \n", + "149 Log2_variant_total \n", + "150 Log2_SNP_total \n", + "151 Log2_INDEL_total \n", + "152 Genomics_subtype \n", + "153 Mutation_signature_C>A \n", + "154 Mutation_signature_C>G \n", + "155 Mutation_signature_C>T \n", + "156 Mutation_signature_T>C \n", + "157 Mutation_signature_T>A \n", + "158 Mutation_signature_T>G \n", + "159 WXS_normal_sample_type \n", + "160 WXS_normal_filename \n", + "161 WXS_normal_UUID \n", + "162 WXS_tumor_sample_type \n", + "163 WXS_tumor_filename \n", + "164 WXS_tumor_UUID \n", + "165 WGS_normal_sample_type \n", + "166 WGS_normal_UUID \n", + "167 WGS_tumor_sample_type \n", + "168 WGS_tumor_UUID \n", + "169 RNAseq_R1_sample_type \n", + "170 RNAseq_R1_filename \n", + "171 RNAseq_R1_UUID \n", + "172 RNAseq_R2_sample_type \n", + "173 RNAseq_R2_filename \n", + "174 RNAseq_R2_UUID \n", + "175 miRNAseq_sample_type \n", + "176 miRNAseq_UUID \n", + "177 Methylation_available \n", + "178 Methylation_quality \n", + "\n", + " target \n", + "0 xCell_T_cell_CD4+_Th1 \n", + "1 Idx \n", + "2 Case_excluded \n", + "3 ABSOLUTE_tumor_purity \n", + "4 Number_of_para-aortic_lymph_nodes_examined \n", + "5 ReporterName \n", + "6 Idx \n", + "7 Aliquot_ID \n", + "8 Group \n", + "9 POLE \n", + "10 Participant_country \n", + "11 Histologic_grade \n", + "12 Myometrial_invasion_present_specify \n", + "13 Histologic_Type \n", + "14 Follow-up_additional_treatment_radiation_thera... \n", + "15 Tumor_necrosis \n", + "16 Pathologic_staging_primary_tumor_pt \n", + "17 Pathologic_staging_regional_lymph_nodes_pn \n", + "18 Clinical_staging_distant_metastasis_cm \n", + "19 Clinical_staging_distant_metastasis_cm \n", + "20 Tumor_stage_pathological \n", + "21 Pathologic_staging_primary_tumor_pt \n", + "22 Number_of_pelvic_lymph_nodes_examined \n", + "23 BMI \n", + "24 Age \n", + "25 Diabetes \n", + "26 Race \n", + "27 Ethnicity \n", + "28 Sex \n", + "29 Tumor_site \n", + "30 Tumor_site_other \n", + "31 Tumor_focality \n", + "32 Tumor_size_cm \n", + "33 Ancillary_studies_estrogen_receptor \n", + "34 Ancillary_studies_estrogen_receptor \n", + "35 Ancillary_studies_progesterone_receptor \n", + "36 Ancillary_studies_progesterone_receptor \n", + "37 Ancillary_studies_mlh1 \n", + "38 Ancillary_studies_mlh1 \n", + "39 Ancillary_studies_msh2 \n", + "40 Ancillary_studies_pms2 \n", + "41 Ancillary_studies_p53 \n", + "42 Ancillary_studies_other_immunohistochemistry_t... \n", + "43 Ancillary_studies_mlh1_promoter_hypermethylation \n", + "44 Donor_information_number_of_full_term_pregnancies \n", + "45 Progeny_JAK.STAT \n", + "46 Aliquot_ID \n", + "47 Aliquot_ID \n", + "48 xCell_T_cell_CD4+_Th2 \n", + "49 Progeny_PI3K \n", + "50 Cibersort_Macrophage_M2 \n", + "51 xCell_NK_cell \n", + "52 xCell_Cancer_associated_fibroblast \n", + "53 xCell_Cancer_associated_fibroblast \n", + "54 xCell_Cancer_associated_fibroblast \n", + "55 Progeny_PI3K \n", + "56 xCell_T_cell_CD4+_Th2 \n", + "57 Cibersort_T_cell_CD4+_naive \n", + "58 CNV_ratio \n", + "59 xCell_T_cell_CD4+_Th2 \n", + "60 xCell_Cancer_associated_fibroblast \n", + "61 Progeny_TGFb \n", + "62 Progeny_TGFb \n", + "63 Cibersort_NK_cell_activated \n", + "64 Cibersort_NK_cell_activated \n", + "65 Cibersort_Macrophage_M2 \n", + "66 Cibersort_Macrophage_M0 \n", + "67 Cibersort_Macrophage_M0 \n", + "68 Cibersort_Macrophage_M2 \n", + "69 xCell_Cancer_associated_fibroblast \n", + "70 xCell_Cancer_associated_fibroblast \n", + "71 Cibersort_Mast_cell_activated \n", + "72 Cibersort_Mast_cell_activated \n", + "73 xCell_Cancer_associated_fibroblast \n", + "74 CNV_ratio \n", + "75 Cibersort_T_cell_follicular_helper \n", + "76 Estimate_StromalScore \n", + "77 Estimate_ESTIMATEScore \n", + "78 Estimate_ESTIMATEScore \n", + "79 Progeny_Androgen \n", + "80 xCell_stroma_score \n", + "81 Progeny_Trail \n", + "82 Progeny_Trail \n", + "83 xCell_stroma_score \n", + "84 Mutation_signature_SBS1 \n", + "85 BMI \n", + "86 Progeny_NFkB \n", + "87 Pathologic_staging_regional_lymph_nodes_pn \n", + "88 ABSOLUTE_tumor_purity \n", + "89 Pathologic_staging_primary_tumor_pt \n", + "90 Pathologic_staging_primary_tumor_pt \n", + "91 Progeny_VEGF \n", + "92 xCell_stroma_score \n", + "93 TP53 \n", + "94 Cibersort_T_cell_CD4+_naive \n", + "95 TP53 \n", + "96 Ancillary_studies_pms2 \n", + "97 TP53 \n", + "98 TP53 \n", + "99 PIK3CA \n", + "100 PIK3CA \n", + "101 PIK3CA \n", + "102 PIK3CA \n", + "103 PIK3CA \n", + "104 PIK3CA \n", + "105 PIK3CA \n", + "106 PIK3CA \n", + "107 PIK3CA \n", + "108 PIK3CA \n", + "109 PIK3CA \n", + "110 PIK3CA \n", + "111 PIK3CA \n", + "112 PIK3CA \n", + "113 PIK3CA \n", + "114 PIK3CA \n", + "115 PIK3CA \n", + "116 PIK3CA \n", + "117 PIK3CA \n", + "118 PIK3CA \n", + "119 PIK3CA \n", + "120 PIK3CA \n", + "121 PIK3CA \n", + "122 PIK3CA \n", + "123 PIK3CA \n", + "124 PIK3CA \n", + "125 PIK3CA \n", + "126 Batch \n", + "127 Batch \n", + "128 Batch \n", + "129 CNV_ratio \n", + "130 CNV_ratio \n", + "131 CNV_status \n", + "132 CNV_ratio \n", + "133 CNV_ratio \n", + "134 Idx \n", + "135 CNV_ratio \n", + "136 CNV_ratio \n", + "137 CNV_ratio \n", + "138 CNV_ratio \n", + "139 Progeny_Androgen \n", + "140 Progeny_Androgen \n", + "141 Progeny_Androgen \n", + "142 MSI_status \n", + "143 POLE \n", + "144 MSI_status \n", + "145 BMI \n", + "146 Progeny_MAPK \n", + "147 Progeny_JAK.STAT \n", + "148 Cibersort_Macrophage_M0 \n", + "149 Estimate_ESTIMATEScore \n", + "150 CNV_ratio \n", + "151 Estimate_ESTIMATEScore \n", + "152 Genomic_subtype \n", + "153 CNV_ratio \n", + "154 Cibersort_Macrophage_M2 \n", + "155 xCell_Cancer_associated_fibroblast \n", + "156 Cibersort_Macrophage_M2 \n", + "157 Progeny_Hypoxia \n", + "158 Progeny_TGFb \n", + "159 Batch \n", + "160 Progeny_WNT \n", + "161 Case_id \n", + "162 Tumor_site \n", + "163 Progeny_TGFb \n", + "164 Progeny_TGFb \n", + "165 Mutation_signature_SBS7a \n", + "166 Case_id \n", + "167 Tumor_site \n", + "168 Progeny_TGFb \n", + "169 ARID1A \n", + "170 Aliquot_ID \n", + "171 Case_id \n", + "172 ARID1A \n", + "173 Aliquot_ID \n", + "174 Case_id \n", + "175 Mutation_signature_SBS7a \n", + "176 Case_id \n", + "177 Mutation_signature_SBS42 \n", + "178 MSI_status " + ] + }, + "execution_count": 9, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "pd.set_option('display.max_rows', None)\n", + "schema_mapping = bdi.match_schema(df_source, df_target, method=\"ct_learning\")\n", + "schema_mapping" + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Extracting features from 1 columns...\n" + ] + }, + { + "data": { + "application/vnd.jupyter.widget-view+json": { + "model_id": 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sourcetargetsimilarity
0Tumor_purityTumor_size_cm0.108482
1Tumor_purityABSOLUTE_tumor_purity0.099089
2Tumor_purityMutation_signature_SBS10b0.094293
3Tumor_purityCibersort_T_cell_regulatory_(Tregs)0.092900
4Tumor_purityCibersort_Monocyte0.092766
5Tumor_purityCibersort_B_cell_naive0.092648
6Tumor_purityMutation_signature_SBS10.092625
7Tumor_purityCibersort_T_cell_gamma_delta0.091828
8Tumor_purityProgeny_TGFb0.090625
9Tumor_purityMutation_signature_SBS10a0.090585
10Tumor_purityPathologic_staging_primary_tumor_pt0.089843
11Tumor_purityMutation_signature_SBS7a0.089825
12Tumor_purityMutation_signature_SBS60.089275
13Tumor_purityMutation_signature_SBS420.089130
14Tumor_purityMutation_signature_SBS50.088617
15Tumor_purityProgeny_TNFa0.088416
16Tumor_purityMutation_signature_SBS150.088232
17Tumor_purityPlex0.087975
18Tumor_purityBMI0.087312
19Tumor_purityFollow-up_tumor_status_at_date_of_last_contact...0.087292
20Tumor_purityCibersort_T_cell_CD8+0.087164
21Tumor_purityxCell_Monocyte0.087080
22Tumor_purityxCell_T_cell_gamma_delta0.086970
23Tumor_purityxCell_T_cell_CD8+_naive0.086835
24Tumor_purityTumor_site0.086777
25Tumor_purityMutation_signature_SBS200.086773
26Tumor_purityCibersort_Mast_cell_resting0.086565
27Tumor_purityCibersort_B_cell_memory0.086439
28Tumor_purityTumor_necrosis0.086347
29Tumor_purityWas_the_participant_exposed_to_secondhand_smoke0.085964
30Tumor_purityxCell_T_cell_regulatory_(Tregs)0.085852
31Tumor_purityMutation_signature_SBS210.085632
32Tumor_purityCibersort_T_cell_follicular_helper0.085575
33Tumor_purityCurrent_medications_medication_name_vitamins_s...0.085556
34Tumor_purityxCell_T_cell_CD4+_naive0.085543
\n", + "" + ], + "text/plain": [ + " source target \\\n", + "0 Tumor_purity Tumor_size_cm \n", + "1 Tumor_purity ABSOLUTE_tumor_purity \n", + "2 Tumor_purity Mutation_signature_SBS10b \n", + "3 Tumor_purity Cibersort_T_cell_regulatory_(Tregs) \n", + "4 Tumor_purity Cibersort_Monocyte \n", + "5 Tumor_purity Cibersort_B_cell_naive \n", + "6 Tumor_purity Mutation_signature_SBS1 \n", + "7 Tumor_purity Cibersort_T_cell_gamma_delta \n", + "8 Tumor_purity Progeny_TGFb \n", + "9 Tumor_purity Mutation_signature_SBS10a \n", + "10 Tumor_purity Pathologic_staging_primary_tumor_pt \n", + "11 Tumor_purity Mutation_signature_SBS7a \n", + "12 Tumor_purity Mutation_signature_SBS6 \n", + "13 Tumor_purity Mutation_signature_SBS42 \n", + "14 Tumor_purity Mutation_signature_SBS5 \n", + "15 Tumor_purity Progeny_TNFa \n", + "16 Tumor_purity Mutation_signature_SBS15 \n", + "17 Tumor_purity Plex \n", + "18 Tumor_purity BMI \n", + "19 Tumor_purity Follow-up_tumor_status_at_date_of_last_contact... \n", + "20 Tumor_purity Cibersort_T_cell_CD8+ \n", + "21 Tumor_purity xCell_Monocyte \n", + "22 Tumor_purity xCell_T_cell_gamma_delta \n", + "23 Tumor_purity xCell_T_cell_CD8+_naive \n", + "24 Tumor_purity Tumor_site \n", + "25 Tumor_purity Mutation_signature_SBS20 \n", + "26 Tumor_purity Cibersort_Mast_cell_resting \n", + "27 Tumor_purity Cibersort_B_cell_memory \n", + "28 Tumor_purity Tumor_necrosis \n", + "29 Tumor_purity Was_the_participant_exposed_to_secondhand_smoke \n", + "30 Tumor_purity xCell_T_cell_regulatory_(Tregs) \n", + "31 Tumor_purity Mutation_signature_SBS21 \n", + "32 Tumor_purity Cibersort_T_cell_follicular_helper \n", + "33 Tumor_purity Current_medications_medication_name_vitamins_s... \n", + "34 Tumor_purity xCell_T_cell_CD4+_naive \n", + "\n", + " similarity \n", + "0 0.108482 \n", + "1 0.099089 \n", + "2 0.094293 \n", + "3 0.092900 \n", + "4 0.092766 \n", + "5 0.092648 \n", + "6 0.092625 \n", + "7 0.091828 \n", + "8 0.090625 \n", + "9 0.090585 \n", + "10 0.089843 \n", + "11 0.089825 \n", + "12 0.089275 \n", + "13 0.089130 \n", + "14 0.088617 \n", + "15 0.088416 \n", + "16 0.088232 \n", + "17 0.087975 \n", + "18 0.087312 \n", + "19 0.087292 \n", + "20 0.087164 \n", + "21 0.087080 \n", + "22 0.086970 \n", + "23 0.086835 \n", + "24 0.086777 \n", + "25 0.086773 \n", + "26 0.086565 \n", + "27 0.086439 \n", + "28 0.086347 \n", + "29 0.085964 \n", + "30 0.085852 \n", + "31 0.085632 \n", + "32 0.085575 \n", + "33 0.085556 \n", + "34 0.085543 " + ] + }, + "execution_count": 7, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.top_matches(df_source, columns=['Tumor_purity'], target=df_target, top_k=35)" + ] + }, + { + "cell_type": "code", + "execution_count": 21, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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value_name
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3Other(Mohs treatment)
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" + ], + "text/plain": [ + " value_name\n", + "0 NaN\n", + "1 Surgery|Surgery\n", + "2 Surgery\n", + "3 Other(Mohs treatment)\n", + "4 Radiation,Surgery\n", + "5 Unknown" + ] + }, + "execution_count": 21, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.preview_domain(df_target, column='Treatment_naive')" + ] + }, + { + "cell_type": "code", + "execution_count": 26, + "metadata": {}, + "outputs": [ + { + "ename": "KeyError", + "evalue": "'Ancillary_studies_mlh2'", + "output_type": "error", + "traceback": [ + "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m", + "\u001b[0;31mKeyError\u001b[0m Traceback (most recent call last)", + "Cell \u001b[0;32mIn[26], line 2\u001b[0m\n\u001b[1;32m 1\u001b[0m \u001b[38;5;66;03m# Stemness_score\tProgeny_Androgen\u001b[39;00m\n\u001b[0;32m----> 2\u001b[0m \u001b[43mbdi\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mmatch_values\u001b[49m\u001b[43m(\u001b[49m\u001b[43mdf_source\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43mdf_target\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;124;43m'\u001b[39;49m\u001b[38;5;124;43mMLH2\u001b[39;49m\u001b[38;5;124;43m'\u001b[39;49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;124;43m'\u001b[39;49m\u001b[38;5;124;43mAncillary_studies_mlh2\u001b[39;49m\u001b[38;5;124;43m'\u001b[39;49m\u001b[43m)\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43mmethod\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;124;43m'\u001b[39;49m\u001b[38;5;124;43mtfidf\u001b[39;49m\u001b[38;5;124;43m'\u001b[39;49m\u001b[43m)\u001b[49m \n\u001b[1;32m 3\u001b[0m \u001b[38;5;66;03m# bdi.match_values(df_source, df_target, ('Tumor_purity', 'ABSOLUTE_tumor_purity'), method='tfidf')\u001b[39;00m\n", + "File \u001b[0;32m~/workspace/askem-arpa-h/bdi-kit/bdikit/api.py:317\u001b[0m, in \u001b[0;36mmatch_values\u001b[0;34m(source, target, column_mapping, method, method_args)\u001b[0m\n\u001b[1;32m 315\u001b[0m method_args \u001b[38;5;241m=\u001b[39m {}\n\u001b[1;32m 316\u001b[0m value_matcher \u001b[38;5;241m=\u001b[39m ValueMatchers\u001b[38;5;241m.\u001b[39mget_instance(method, \u001b[38;5;241m*\u001b[39m\u001b[38;5;241m*\u001b[39mmethod_args)\n\u001b[0;32m--> 317\u001b[0m matches \u001b[38;5;241m=\u001b[39m \u001b[43m_match_values\u001b[49m\u001b[43m(\u001b[49m\u001b[43msource\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43mtarget_domain\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43mcolumn_mapping_list\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43mvalue_matcher\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 319\u001b[0m result \u001b[38;5;241m=\u001b[39m [\n\u001b[1;32m 320\u001b[0m _value_matching_result_to_df(matching_result) \u001b[38;5;28;01mfor\u001b[39;00m matching_result \u001b[38;5;129;01min\u001b[39;00m matches\n\u001b[1;32m 321\u001b[0m ]\n\u001b[1;32m 323\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m \u001b[38;5;28misinstance\u001b[39m(column_mapping, \u001b[38;5;28mtuple\u001b[39m):\n\u001b[1;32m 324\u001b[0m \u001b[38;5;66;03m# If only a single mapping is provided (as a tuple), we return the result\u001b[39;00m\n\u001b[1;32m 325\u001b[0m \u001b[38;5;66;03m# directly as a DataFrame to make it easier to display it in notebooks.\u001b[39;00m\n", + "File \u001b[0;32m~/workspace/askem-arpa-h/bdi-kit/bdikit/api.py:373\u001b[0m, in \u001b[0;36m_match_values\u001b[0;34m(dataset, target_domain, column_mapping, value_matcher)\u001b[0m\n\u001b[1;32m 370\u001b[0m source_column, target_column \u001b[38;5;241m=\u001b[39m mapping[\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124msource\u001b[39m\u001b[38;5;124m\"\u001b[39m], mapping[\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124mtarget\u001b[39m\u001b[38;5;124m\"\u001b[39m]\n\u001b[1;32m 372\u001b[0m \u001b[38;5;66;03m# 1. Select candidate columns for value mapping\u001b[39;00m\n\u001b[0;32m--> 373\u001b[0m target_domain_list \u001b[38;5;241m=\u001b[39m \u001b[43mtarget_domain\u001b[49m\u001b[43m[\u001b[49m\u001b[43mtarget_column\u001b[49m\u001b[43m]\u001b[49m\n\u001b[1;32m 374\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m target_domain_list \u001b[38;5;129;01mis\u001b[39;00m \u001b[38;5;28;01mNone\u001b[39;00m \u001b[38;5;129;01mor\u001b[39;00m \u001b[38;5;28mlen\u001b[39m(target_domain_list) \u001b[38;5;241m==\u001b[39m \u001b[38;5;241m0\u001b[39m:\n\u001b[1;32m 375\u001b[0m \u001b[38;5;28;01mcontinue\u001b[39;00m\n", + "\u001b[0;31mKeyError\u001b[0m: 'Ancillary_studies_mlh2'" + ] + } + ], + "source": [ + "# Stemness_score\tProgeny_Androgen\n", + "bdi.match_values(df_source, df_target, ('MLH2', 'Ancillary_studies_mlh2'), method='tfidf') \n", + "# bdi.match_values(df_source, df_target, ('Tumor_purity', 'ABSOLUTE_tumor_purity'), method='tfidf')" + ] + }, + { + "cell_type": "code", + "execution_count": 11, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
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sourcetargetsimilarity
0MLH2Ancillary_studies_mlh10.103021
1MLH2BMI0.101541
2MLH2CNV_status0.100899
3MLH2Mutation_signature_SBS210.097867
4MLH2xCell_B_cell0.097845
5MLH2Mutation_load0.096779
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\"\n", + " )\n", + " )\n", + " display(match)" + ] + }, + { + "cell_type": "code", + "execution_count": 11, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "['b4', 'b3', 'b1', 'b2', nan]" + ] + }, + "execution_count": 11, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "list(df_target[\"Batch\"].unique())" + ] + }, + { + "cell_type": "code", + "execution_count": 9, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "['Idx',\n", + " 'Case_id',\n", + " 'Case_excluded',\n", + " 'Batch',\n", + " 'Plex',\n", + " 'ReporterName',\n", + " 'Aliquot_ID',\n", + " 'Group',\n", + " 'Discovery_study',\n", + " 'Age',\n", + " 'Sex',\n", + " 'Histologic_Type',\n", + " 'Histologic_grade',\n", + " 'Tumor_size_cm',\n", + " 'Height_at_time_of_surgery_cm',\n", + " 'Weight_at_time_of_surgery_kg',\n", + " 'BMI',\n", + " 'Myometrial_invasion',\n", + " 'Myometrial_invasion_present_specify',\n", + " 'AJCC_tnm_cancer_staging_edition_used',\n", + " 'Pathologic_staging_primary_tumor_pt',\n", + " 'Pathologic_staging_regional_lymph_nodes_pn',\n", + " 'Number_of_pelvic_lymph_nodes_examined',\n", + " 'Tumor_stage_pathological',\n", + " 'Race',\n", + " 'CNV_ratio',\n", + " 'CNV_status',\n", + " 'POLE',\n", + " 'MSIsensor_ratio',\n", + " 'MSI_status',\n", + " 'Genomic_subtype',\n", + " 'Mutation_load',\n", + " 'TP53',\n", + " 'PTEN',\n", + " 'CTNNB1',\n", + " 'ARID1A',\n", + " 'PIK3CA',\n", + " 'xCell_Myeloid_dendritic_cell_activated',\n", + " 'xCell_B_cell',\n", + " 'xCell_T_cell_CD4+_memory',\n", + " 'xCell_T_cell_CD4+_naive',\n", + " 'xCell_T_cell_CD4+_(non-regulatory)',\n", + " 'xCell_T_cell_CD4+_central_memory',\n", + " 'xCell_T_cell_CD4+_effector_memory',\n", + " 'xCell_T_cell_CD8+_naive',\n", + " 'xCell_T_cell_CD8+',\n", + " 'xCell_T_cell_CD8+_central_memory',\n", + " 'xCell_T_cell_CD8+_effector_memory',\n", + " 'xCell_Class-switched_memory_B_cell',\n", + " 'xCell_Common_lymphoid_progenitor',\n", + " 'xCell_Common_myeloid_progenitor',\n", + " 'xCell_Myeloid_dendritic_cell',\n", + " 'xCell_Endothelial_cell',\n", + " 'xCell_Eosinophil',\n", + " 'xCell_Cancer_associated_fibroblast',\n", + " 'xCell_Granulocyte-monocyte_progenitor',\n", + " 'xCell_Hematopoietic_stem_cell',\n", + " 'xCell_Macrophage',\n", + " 'xCell_Macrophage_M1',\n", + " 'xCell_Macrophage_M2',\n", + " 'xCell_Mast_cell',\n", + " 'xCell_B_cell_memory',\n", + " 'xCell_Monocyte',\n", + " 'xCell_B_cell_naive',\n", + " 'xCell_Neutrophil',\n", + " 'xCell_NK_cell',\n", + " 'xCell_T_cell_NK',\n", + " 'xCell_Plasmacytoid_dendritic_cell',\n", + " 'xCell_B_cell_plasma',\n", + " 'xCell_T_cell_gamma_delta',\n", + " 'xCell_T_cell_CD4+_Th1',\n", + " 'xCell_T_cell_CD4+_Th2',\n", + " 'xCell_T_cell_regulatory_(Tregs)',\n", + " 'xCell_immune_score',\n", + " 'xCell_stroma_score',\n", + " 'xCell_microenvironment_score',\n", + " 'Cibersort_B_cell_naive',\n", + " 'Cibersort_B_cell_memory',\n", + " 'Cibersort_B_cell_plasma',\n", + " 'Cibersort_T_cell_CD8+',\n", + " 'Cibersort_T_cell_CD4+_naive',\n", + " 'Cibersort_T_cell_CD4+_memory_resting',\n", + " 'Cibersort_T_cell_CD4+_memory_activated',\n", + " 'Cibersort_T_cell_follicular_helper',\n", + " 'Cibersort_T_cell_regulatory_(Tregs)',\n", + " 'Cibersort_T_cell_gamma_delta',\n", + " 'Cibersort_NK_cell_resting',\n", + " 'Cibersort_NK_cell_activated',\n", + " 'Cibersort_Monocyte',\n", + " 'Cibersort_Macrophage_M0',\n", + " 'Cibersort_Macrophage_M1',\n", + " 'Cibersort_Macrophage_M2',\n", + " 'Cibersort_Myeloid_dendritic_cell_resting',\n", + " 'Cibersort_Myeloid_dendritic_cell_activated',\n", + " 'Cibersort_Mast_cell_activated',\n", + " 'Cibersort_Mast_cell_resting',\n", + " 'Cibersort_Eosinophil',\n", + " 'Cibersort_Neutrophil',\n", + " 'Mutation_signature_SBS1',\n", + " 'Mutation_signature_SBS5',\n", + " 'Mutation_signature_SBS6',\n", + " 'Mutation_signature_SBS7a',\n", + " 'Mutation_signature_SBS10a',\n", + " 'Mutation_signature_SBS10b',\n", + " 'Mutation_signature_SBS15',\n", + " 'Mutation_signature_SBS20',\n", + " 'Mutation_signature_SBS21',\n", + " 'Mutation_signature_SBS42',\n", + " 'Mutation_signature_SBS54',\n", + " 'ABSOLUTE_tumor_purity',\n", + " 'Diabetes',\n", + " 'Metformin_treatment',\n", + " 'Progeny_Androgen',\n", + " 'Progeny_EGFR',\n", + " 'Progeny_Estrogen',\n", + " 'Progeny_Hypoxia',\n", + " 'Progeny_JAK.STAT',\n", + " 'Progeny_MAPK',\n", + " 'Progeny_NFkB',\n", + " 'Progeny_p53',\n", + " 'Progeny_PI3K',\n", + " 'Progeny_TGFb',\n", + " 'Progeny_TNFa',\n", + " 'Progeny_Trail',\n", + " 'Progeny_VEGF',\n", + " 'Progeny_WNT',\n", + " 'Estimate_StromalScore',\n", + " 'Estimate_ImmuneScore',\n", + " 'Estimate_ESTIMATEScore',\n", + " 'Peritoneal_ascitic_fluid',\n", + " 'Tumor_necrosis',\n", + " 'Margin_status',\n", + " 'Ethnicity',\n", + " 'Ethnicity_race_ancestry_identified',\n", + " 'Participant_country',\n", + " 'Tumor_site',\n", + " 'Tumor_site_other',\n", + " 'Tumor_focality',\n", + " 'Number_of_pelvic_lymph_nodes_positive_for_tumor_by_ihc_staining_only',\n", + " 'Number_of_pelvic_lymph_nodes_positive_for_tumor_by_he',\n", + " 'Number_of_para-aortic_lymph_nodes_examined',\n", + " 'Number_of_para-aortic_lymph_nodes_positive_for_tumor_by_ihc_staining_only',\n", + " 'Number_of_para-aortic_lymph_nodes_positive_for_tumor_by_he',\n", + " 'Number_of_other_lymph_nodes_examined',\n", + " 'Number_of_other_lymph_nodes_positive_for_tumor_by_ihc_staining_only',\n", + " 'Number_of_other_lymph_nodes_positive_for_tumor_by_he',\n", + " 'Clinical_staging_distant_metastasis_cm',\n", + " 'Residual_tumor',\n", + " 'Ancillary_studies_estrogen_receptor',\n", + " 'Ancillary_studies_progesterone_receptor',\n", + " 'Ancillary_studies_mlh1',\n", + " 'Ancillary_studies_msh2',\n", + " 'Ancillary_studies_msh6',\n", + " 'Ancillary_studies_pms2',\n", + " 'Ancillary_studies_p53',\n", + " 'Ancillary_studies_other_immunohistochemistry_performed',\n", + " 'Ancillary_studies_mlh1_promoter_hypermethylation',\n", + " 'Ancillary_studies_other_testing_performed',\n", + " 'Donor_information_menopause_status',\n", + " 'Donor_information_has_the_patient_ever_taken_menopausal_hormone_therapy',\n", + " 'Donor_information_number_of_full_term_pregnancies',\n", + " 'Ancillary_studies_other_immunohistochemistry_type_and_result',\n", + " 'baseline_ancillary_studies_other_testing_type_and_result',\n", + " 'History_of_cancer',\n", + " 'Alcohol_consumption',\n", + " 'Tobacco_smoking_history',\n", + " 'Age_at_which_the_participant_started_smoking',\n", + " 'Age_at_which_the_participant_stopped_smoking',\n", + " 'On_the_days_participant_smoked_how_many_cigarettes_did_he_she_usually_smoke',\n", + " 'Number_of_pack_years_smoked',\n", + " 'Was_the_participant_exposed_to_secondhand_smoke',\n", + " 'Personal_medical_history_history_source',\n", + " 'medical_history_current_medications',\n", + " 'Current_medications_history_source',\n", + " 'Current_medications_medication_name_vitamins_supplements',\n", + " 'Cancer_history_cancer_type',\n", + " 'Cancer_history_history_source',\n", + " 'Cancer_history_history_of_any_treatment',\n", + " 'Cancer_history_medical_record_documentation_of_this_history_of_cancer_and_treatment',\n", + " 'Procurement_blood_collection_minimum_required_blood_collected',\n", + " 'Procurement_blood_collection_number_of_blood_tubes_collected',\n", + " 'Follow-up_follow_up_period',\n", + " 'Follow-up_is_this_patient_lost_to_follow-up',\n", + " 'Follow-up_vital_status_at_date_of_last_contact',\n", + " 'Follow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_last_contact',\n", + " 'Follow-up_adjuvant_post-operative_radiation_therapy',\n", + " 'Follow-up_adjuvant_post-operative_pharmaceutical_therapy',\n", + " 'Follow-up_adjuvant_post-operative_immunological_therapy',\n", + " 'Follow-up_tumor_status_at_date_of_last_contact_or_death',\n", + " 'Follow-up_has_the_patient_ever_taken_menopausal_hormone_therapy',\n", + " 'Follow-up_has_the_patient_ever_taken_oral_contraceptives',\n", + " 'Follow-up_has_the_patient_ever_taken_tamoxifen',\n", + " 'Follow-up_hypertension',\n", + " 'Follow-up_has_the_patient_ever_been_diagnosed_with_diabetes_by_a_physician',\n", + " 'Follow-up_number_of_full_term_pregnancies',\n", + " 'Follow-up_has_the_patient_had_colorectal_cancer',\n", + " 'Follow-up_measure_of_success_of_outcome_at_the_completion_of_initial_first_course_treatment',\n", + " 'Follow-up_measure_of_success_of_outcome_at_completion_of_this_follow-up_form',\n", + " 'Follow-up_measure_of_success_of_outcome_at_date_of_last_contact_or_death',\n", + " 'follow-up_new_tumor_after_initial_treatment',\n", + " 'Follow-up_type_of_new_tumor',\n", + " 'Follow-up_site_of_new_tumor',\n", + " 'Follow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_new_tumor_after_initial_treatment',\n", + " 'Follow-up_additional_surgery_for_new_tumor',\n", + " 'Follow-up_additional_treatment_radiation_therapy_for_new_tumor',\n", + " 'Follow-up_additional_treatment_pharmaceutical_therapy_for_new_tumor',\n", + " 'Follow-up_additional_treatment_immuno_for_new_tumor',\n", + " 'Follow-up_days_from_date_of_collection_to_date_of_last_contact',\n", + " 'Follow-up_cause_of_death',\n", + " 'Follow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_death',\n", + " 'Follow-up_days_from_date_of_initial_pathologic_diagnosis_to_date_of_additional_surgery_for_new_tumor',\n", + " 'Follow-up_procedure_type_of_new_tumor',\n", + " 'Follow-up_residual_tumor_after_surgery_for_new_tumor']" + ] + }, + "execution_count": 9, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "list(df_target.columns)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "#### Generating a harmonized table" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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participant_countrysextumor_stage_pathologicalpathologic_staging_regional_lymph_nodes_pntumor_focality
0United StatesFemaleStage IApN0Unifocal
1United StatesFemaleStage IVpNXUnifocal
2United StatesFemaleStage IApN0Unifocal
3NaNNaNNaNNaNNaN
4United StatesFemaleStage IApNXUnifocal
..................
99NoneFemaleStage IApNXUnifocal
100NoneFemaleStage IIIpN0Unifocal
101United StatesFemaleStage IIIpN0Unifocal
102NoneFemaleStage IApN0Unifocal
103NoneNaNNaNNaNNaN
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" + ], + "text/plain": [ + " participant_country sex tumor_stage_pathological \\\n", + "0 United States Female Stage IA \n", + "1 United States Female Stage IV \n", + "2 United States Female Stage IA \n", + "3 NaN NaN NaN \n", + "4 United States Female Stage IA \n", + ".. ... ... ... \n", + "99 None Female Stage IA \n", + "100 None Female Stage III \n", + "101 United States Female Stage III \n", + "102 None Female Stage IA \n", + "103 None NaN NaN \n", + "\n", + " pathologic_staging_regional_lymph_nodes_pn tumor_focality \n", + "0 pN0 Unifocal \n", + "1 pNX Unifocal \n", + "2 pN0 Unifocal \n", + "3 NaN NaN \n", + "4 pNX Unifocal \n", + ".. ... ... \n", + "99 pNX Unifocal \n", + "100 pN0 Unifocal \n", + "101 pN0 Unifocal \n", + "102 pN0 Unifocal \n", + "103 NaN NaN \n", + "\n", + "[104 rows x 5 columns]" + ] + }, + "execution_count": 6, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "df_mapped = bdi.materialize_mapping(df_source, value_matches)\n", + "df_mapped" + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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CountryGenderFIGO_stagePath_Stage_Reg_Lymph_Nodes-pNtumor_Stage-PathologicalTumor_Focality
0United StatesFemaleIApN0Stage IUnifocal
1United StatesFemaleIApNXStage IVUnifocal
2United StatesFemaleIApN0Stage IUnifocal
3NaNNaNNaNNaNNaNNaN
4United StatesFemaleIApNXStage IUnifocal
.....................
99UkraineFemaleIApNXStage IUnifocal
100UkraineFemaleIIpN0Stage IIUnifocal
101United StatesFemaleIIpN0Stage IIUnifocal
102UkraineFemaleIApN0Stage IUnifocal
103UkraineNaNNaNNaNNaNNaN
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" + ], + "text/plain": [ + " Country Gender FIGO_stage Path_Stage_Reg_Lymph_Nodes-pN \\\n", + "0 United States Female IA pN0 \n", + "1 United States Female IA pNX \n", + "2 United States Female IA pN0 \n", + "3 NaN NaN NaN NaN \n", + "4 United States Female IA pNX \n", + ".. ... ... ... ... \n", + "99 Ukraine Female IA pNX \n", + "100 Ukraine Female II pN0 \n", + "101 United States Female II pN0 \n", + "102 Ukraine Female IA pN0 \n", + "103 Ukraine NaN NaN NaN \n", + "\n", + " tumor_Stage-Pathological Tumor_Focality \n", + "0 Stage I Unifocal \n", + "1 Stage IV Unifocal \n", + "2 Stage I Unifocal \n", + "3 NaN NaN \n", + "4 Stage I Unifocal \n", + ".. ... ... \n", + "99 Stage I Unifocal \n", + "100 Stage II Unifocal \n", + "101 Stage II Unifocal \n", + "102 Stage I Unifocal \n", + "103 NaN NaN \n", + "\n", + "[104 rows x 6 columns]" + ] + }, + "execution_count": 7, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "source_column_names = list(map(lambda m: m.attrs['source'], value_matches))\n", + "target_column_names = list(map(lambda m: m.attrs['target'], value_matches))\n", + "df_source[source_column_names]" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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participant_countrysextumor_stage_pathologicalpathologic_staging_regional_lymph_nodes_pntumor_stage_pathologicaltumor_focality
0United StatesFemaleStage IApN0Stage IAUnifocal
1United StatesFemaleStage IVpNXStage IVUnifocal
2United StatesFemaleStage IApN0Stage IAUnifocal
3NaNNaNNaNNaNNaNNaN
4United StatesFemaleStage IApNXStage IAUnifocal
.....................
135PolandMaleStage IIIpN2Stage IIIUnifocal
136ChinaFemaleStage IIIpN2Stage IIIUnifocal
137ChinaMaleStage IIIpN2Stage IIIUnifocal
138PolandFemaleStage IIIpN2Stage IIIMultifocal
139PolandFemaleStage IIIpN2Stage IIIUnifocal
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244 rows × 6 columns

\n", + "
" + ], + "text/plain": [ + " participant_country sex tumor_stage_pathological \\\n", + "0 United States Female Stage IA \n", + "1 United States Female Stage IV \n", + "2 United States Female Stage IA \n", + "3 NaN NaN NaN \n", + "4 United States Female Stage IA \n", + ".. ... ... ... \n", + "135 Poland Male Stage III \n", + "136 China Female Stage III \n", + "137 China Male Stage III \n", + "138 Poland Female Stage III \n", + "139 Poland Female Stage III \n", + "\n", + " pathologic_staging_regional_lymph_nodes_pn tumor_stage_pathological \\\n", + "0 pN0 Stage IA \n", + "1 pNX Stage IV \n", + "2 pN0 Stage IA \n", + "3 NaN NaN \n", + "4 pNX Stage IA \n", + ".. ... ... \n", + "135 pN2 Stage III \n", + "136 pN2 Stage III \n", + "137 pN2 Stage III \n", + "138 pN2 Stage III \n", + "139 pN2 Stage III \n", + "\n", + " tumor_focality \n", + "0 Unifocal \n", + "1 Unifocal \n", + "2 Unifocal \n", + "3 NaN \n", + "4 Unifocal \n", + ".. ... \n", + "135 Unifocal \n", + "136 Unifocal \n", + "137 Unifocal \n", + "138 Multifocal \n", + "139 Unifocal \n", + "\n", + "[244 rows x 6 columns]" + ] + }, + "execution_count": 8, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "pd.concat([df_mapped[target_column_names], df_target[target_column_names]])" + ] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.10.12" + } + }, + "nbformat": 4, + "nbformat_minor": 4 +} diff --git a/examples/demo.ipynb b/examples/demo.ipynb index 3fc6ee7b..7e8c6948 100644 --- a/examples/demo.ipynb +++ b/examples/demo.ipynb @@ -70,133 +70,373 @@ " \n", " \n", " \n", - " Country\n", - " Gender\n", - " FIGO_stage\n", - " Path_Stage_Reg_Lymph_Nodes-pN\n", - " tumor_Stage-Pathological\n", - " Tumor_Focality\n", + " case_id\n", + " age\n", + " gender\n", + " country\n", + " smoking_history\n", + " smoke_age_start\n", + " smoke_age_stop\n", + " num_smoke_per_day\n", + " num_pack_years_sm\n", + " smoking_second_hand\n", + " ...\n", + " tumor_pathology_review\n", + " ESTIMATE_stromal_score\n", + " ESTIMATE_immune_score\n", + " CD3_IHC_count\n", + " stemness_score\n", + " mutation_count\n", + " neoAntigen_count\n", + " chr_instability_idx\n", + " integrated_subtype\n", + " transcriptomic_subtype\n", " \n", " \n", " \n", " \n", " 0\n", - " United States\n", - " Female\n", - " IA\n", - " pN0\n", - " Stage I\n", - " Unifocal\n", + " C3L-00977\n", + " 56\n", + " Male\n", + " Russia\n", + " Current reformed smoker, years unknown\n", + " NaN\n", + " NaN\n", + " 20\n", + " NaN\n", + " Yes\n", + " ...\n", + " SCC 80%\n", + " 6825.995755\n", + " 7989.115925\n", + " 1.0\n", + " 0.953243\n", + " 106\n", + " 0\n", + " 2.003654\n", + " Basal\n", + " Mesenchymal\n", " \n", " \n", " 1\n", - " United States\n", - " Female\n", - " IA\n", - " pNX\n", - " Stage IV\n", - " Unifocal\n", + " C3L-00987\n", + " 61\n", + " Male\n", + " Ukraine\n", + " Current smoker: Includes daily and non-daily s...\n", + " 18\n", + " NaN\n", + " 20\n", + " 43.0\n", + " Yes\n", + " ...\n", + " SCC 90%;SCC 90%;SCC 80%;SCC 70%\n", + " 5999.793467\n", + " 4772.409716\n", + " 0.0\n", + " 0.825330\n", + " 83\n", + " 0\n", + " 5.205612\n", + " CIN\n", + " Classical\n", " \n", " \n", " 2\n", - " United States\n", - " Female\n", - " IA\n", - " pN0\n", - " Stage I\n", - " Unifocal\n", + " C3L-00994\n", + " 50\n", + " Male\n", + " Ukraine\n", + " Current reformed smoker within past 15 years\n", + " 16\n", + " 50\n", + " 6\n", + " 10.2\n", + " Exposure to secondhand smoke history not avail...\n", + " ...\n", + " SCC 40%;SCC 70%;SCC 40%;SCC 75%\n", + " 8924.036564\n", + " 8176.233903\n", + " 5.0\n", + " 0.664581\n", + " 67\n", + " 0\n", + " 1.684475\n", + " Immune\n", + " Mesenchymal\n", " \n", " \n", " 3\n", - " NaN\n", - " NaN\n", - " NaN\n", - " NaN\n", - " NaN\n", - " NaN\n", + " C3L-00995\n", + " 56\n", + " Male\n", + " Ukraine\n", + " Current reformed smoker, more than 15 years\n", + " 25\n", + " 56\n", + " 20\n", + " 31.0\n", + " Exposure to secondhand smoke history not avail...\n", + " ...\n", + " SCC 90%;SCC 80%;SCC 40%;SCC 70%\n", + " 8723.429667\n", + " 8342.246345\n", + " 70.0\n", + " 0.539918\n", + " 64\n", + " 0\n", + " 1.340483\n", + " Immune\n", + " Mesenchymal\n", " \n", " \n", " 4\n", - " United States\n", - " Female\n", - " IA\n", - " pNX\n", - " Stage I\n", - " Unifocal\n", + " C3L-00997\n", + " 47\n", + " Male\n", + " Ukraine\n", + " Current reformed smoker, more than 15 years\n", + " 12\n", + " 27\n", + " 20\n", + " 15.0\n", + " Yes\n", + " ...\n", + " SCC 70%;SCC 70%\n", + " 7025.911695\n", + " 7445.251991\n", + " 60.0\n", + " 0.843765\n", + " 129\n", + " 0\n", + " 3.906370\n", + " CIN\n", + " Classical\n", " \n", " \n", " 5\n", - " United States\n", - " Female\n", - " IA\n", - " pNX\n", - " Stage I\n", - " Unifocal\n", + " C3L-00999\n", + " 56\n", + " Male\n", + " Russia\n", + " Current smoker: Includes daily and non-daily s...\n", + " 20\n", + " NaN\n", + " 20\n", + " 36.0\n", + " Yes\n", + " ...\n", + " SCC 80%;SCC 70%\n", + " 8510.704551\n", + " 8210.549555\n", + " 30.0\n", + " 0.548977\n", + " 159\n", + " 0\n", + " 1.148834\n", + " Immune\n", + " Atypical\n", " \n", " \n", " 6\n", - " United States\n", - " Female\n", - " IA\n", - " pNX\n", - " Stage I\n", - " Unifocal\n", + " C3L-01138\n", + " 62\n", + " Male\n", + " Ukraine\n", + " Current smoker: Includes daily and non-daily s...\n", + " 8\n", + " NaN\n", + " 20\n", + " 54.0\n", + " Exposure to secondhand smoke history not avail...\n", + " ...\n", + " SCC 70%\n", + " 6283.423855\n", + " 6407.893478\n", + " 10.0\n", + " 0.890790\n", + " 187\n", + " 1\n", + " 3.924982\n", + " Basal\n", + " Classical\n", " \n", " \n", " 7\n", - " Other_specify\n", - " Female\n", - " IA\n", - " pNX\n", - " Stage I\n", - " Unifocal\n", + " C3L-01237\n", + " 57\n", + " Male\n", + " Ukraine\n", + " Current reformed smoker, more than 15 years\n", + " 17\n", + " 20\n", + " 40\n", + " 6.0\n", + " Exposure to secondhand smoke history not avail...\n", + " ...\n", + " SCC 80%\n", + " 7175.667725\n", + " 5720.287055\n", + " 30.0\n", + " 0.738328\n", + " 141\n", + " 1\n", + " 4.286490\n", + " CIN\n", + " Classical\n", " \n", " \n", " 8\n", - " United States\n", - " Female\n", - " IIIA\n", - " pNX\n", - " Stage III\n", - " Unifocal\n", + " C3L-02617\n", + " 64\n", + " Male\n", + " Bulgaria\n", + " Current smoker: Includes daily and non-daily s...\n", + " 20\n", + " NaN\n", + " 30\n", + " 66.0\n", + " Yes\n", + " ...\n", + " SCC 90%;SCC 80%;SCC 80%;SCC 80%;SCC 80%\n", + " 6346.815584\n", + " 6958.573390\n", + " NaN\n", + " 0.906466\n", + " 470\n", + " 1\n", + " 4.744818\n", + " CIN\n", + " Classical\n", " \n", " \n", " 9\n", - " United States\n", - " Female\n", - " IA\n", - " pN0\n", - " Stage I\n", - " Unifocal\n", + " C3L-02621\n", + " 68\n", + " Male\n", + " Bulgaria\n", + " Current smoker: Includes daily and non-daily s...\n", + " 38\n", + " NaN\n", + " 30\n", + " 45.0\n", + " Yes\n", + " ...\n", + " SCC 70%;SCC 70%;SCC 70%;SCC 70%;SCC 65%\n", + " 6806.384264\n", + " 8039.787184\n", + " NaN\n", + " 0.754950\n", + " 358\n", + " 0\n", + " 1.774521\n", + " CIN\n", + " Atypical\n", " \n", " \n", "\n", + "

10 rows × 37 columns

\n", "" ], "text/plain": [ - " Country Gender FIGO_stage Path_Stage_Reg_Lymph_Nodes-pN \\\n", - "0 United States Female IA pN0 \n", - "1 United States Female IA pNX \n", - "2 United States Female IA pN0 \n", - "3 NaN NaN NaN NaN \n", - "4 United States Female IA pNX \n", - "5 United States Female IA pNX \n", - "6 United States Female IA pNX \n", - "7 Other_specify Female IA pNX \n", - "8 United States Female IIIA pNX \n", - "9 United States Female IA pN0 \n", + " case_id age gender country \\\n", + "0 C3L-00977 56 Male Russia \n", + "1 C3L-00987 61 Male Ukraine \n", + "2 C3L-00994 50 Male Ukraine \n", + "3 C3L-00995 56 Male Ukraine \n", + "4 C3L-00997 47 Male Ukraine \n", + "5 C3L-00999 56 Male Russia \n", + "6 C3L-01138 62 Male Ukraine \n", + "7 C3L-01237 57 Male Ukraine \n", + "8 C3L-02617 64 Male Bulgaria \n", + "9 C3L-02621 68 Male Bulgaria \n", "\n", - " tumor_Stage-Pathological Tumor_Focality \n", - "0 Stage I Unifocal \n", - "1 Stage IV Unifocal \n", - "2 Stage I Unifocal \n", - "3 NaN NaN \n", - "4 Stage I Unifocal \n", - "5 Stage I Unifocal \n", - "6 Stage I Unifocal \n", - "7 Stage I Unifocal \n", - "8 Stage III Unifocal \n", - "9 Stage I Unifocal " + " smoking_history smoke_age_start \\\n", + "0 Current reformed smoker, years unknown NaN \n", + "1 Current smoker: Includes daily and non-daily s... 18 \n", + "2 Current reformed smoker within past 15 years 16 \n", + "3 Current reformed smoker, more than 15 years 25 \n", + "4 Current reformed smoker, more than 15 years 12 \n", + "5 Current smoker: Includes daily and non-daily s... 20 \n", + "6 Current smoker: Includes daily and non-daily s... 8 \n", + "7 Current reformed smoker, more than 15 years 17 \n", + "8 Current smoker: Includes daily and non-daily s... 20 \n", + "9 Current smoker: Includes daily and non-daily s... 38 \n", + "\n", + " smoke_age_stop num_smoke_per_day num_pack_years_sm \\\n", + "0 NaN 20 NaN \n", + "1 NaN 20 43.0 \n", + "2 50 6 10.2 \n", + "3 56 20 31.0 \n", + "4 27 20 15.0 \n", + "5 NaN 20 36.0 \n", + "6 NaN 20 54.0 \n", + "7 20 40 6.0 \n", + "8 NaN 30 66.0 \n", + "9 NaN 30 45.0 \n", + "\n", + " smoking_second_hand ... \\\n", + "0 Yes ... \n", + "1 Yes ... \n", + "2 Exposure to secondhand smoke history not avail... ... \n", + "3 Exposure to secondhand smoke history not avail... ... \n", + "4 Yes ... \n", + "5 Yes ... \n", + "6 Exposure to secondhand smoke history not avail... ... \n", + "7 Exposure to secondhand smoke history not avail... ... \n", + "8 Yes ... \n", + "9 Yes ... \n", + "\n", + " tumor_pathology_review ESTIMATE_stromal_score \\\n", + "0 SCC 80% 6825.995755 \n", + "1 SCC 90%;SCC 90%;SCC 80%;SCC 70% 5999.793467 \n", + "2 SCC 40%;SCC 70%;SCC 40%;SCC 75% 8924.036564 \n", + "3 SCC 90%;SCC 80%;SCC 40%;SCC 70% 8723.429667 \n", + "4 SCC 70%;SCC 70% 7025.911695 \n", + "5 SCC 80%;SCC 70% 8510.704551 \n", + "6 SCC 70% 6283.423855 \n", + "7 SCC 80% 7175.667725 \n", + "8 SCC 90%;SCC 80%;SCC 80%;SCC 80%;SCC 80% 6346.815584 \n", + "9 SCC 70%;SCC 70%;SCC 70%;SCC 70%;SCC 65% 6806.384264 \n", + "\n", + " ESTIMATE_immune_score CD3_IHC_count stemness_score mutation_count \\\n", + "0 7989.115925 1.0 0.953243 106 \n", + "1 4772.409716 0.0 0.825330 83 \n", + "2 8176.233903 5.0 0.664581 67 \n", + "3 8342.246345 70.0 0.539918 64 \n", + "4 7445.251991 60.0 0.843765 129 \n", + "5 8210.549555 30.0 0.548977 159 \n", + "6 6407.893478 10.0 0.890790 187 \n", + "7 5720.287055 30.0 0.738328 141 \n", + "8 6958.573390 NaN 0.906466 470 \n", + "9 8039.787184 NaN 0.754950 358 \n", + "\n", + " neoAntigen_count chr_instability_idx integrated_subtype \\\n", + "0 0 2.003654 Basal \n", + "1 0 5.205612 CIN \n", + "2 0 1.684475 Immune \n", + "3 0 1.340483 Immune \n", + "4 0 3.906370 CIN \n", + "5 0 1.148834 Immune \n", + "6 1 3.924982 Basal \n", + "7 1 4.286490 CIN \n", + "8 1 4.744818 CIN \n", + "9 0 1.774521 CIN \n", + "\n", + " transcriptomic_subtype \n", + "0 Mesenchymal \n", + "1 Classical \n", + "2 Mesenchymal \n", + "3 Mesenchymal \n", + "4 Classical \n", + "5 Atypical \n", + "6 Classical \n", + "7 Classical \n", + "8 Classical \n", + "9 Atypical \n", + "\n", + "[10 rows x 37 columns]" ] }, "execution_count": 2, @@ -205,16 +445,16 @@ } ], "source": [ - "df_source = pd.read_csv(\"./datasets/dou.csv\")\n", - "column_names = [\n", - " \"Country\",\n", - " \"Gender\",\n", - " \"FIGO_stage\",\n", - " \"Path_Stage_Reg_Lymph_Nodes-pN\",\n", - " \"tumor_Stage-Pathological\",\n", - " \"Tumor_Focality\",\n", - "]\n", - "df_source = df_source[column_names]\n", + "df_source = pd.read_csv(\"./datasets/Huang.csv\")\n", + "# column_names = [\n", + "# \"Country\",\n", + "# \"Gender\",\n", + "# \"FIGO_stage\",\n", + "# \"Path_Stage_Reg_Lymph_Nodes-pN\",\n", + "# \"tumor_Stage-Pathological\",\n", + "# \"Tumor_Focality\",\n", + "# ]\n", + "# df_source = df_source[column_names]\n", "df_source.head(10)" ] }, @@ -467,15 +707,22 @@ "execution_count": 4, "metadata": {}, "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Extracting features from 37 columns...\n" + ] + }, { "data": { "application/vnd.jupyter.widget-view+json": { - "model_id": "32cb8bd8acad4941be9dda4e11a51c4f", + "model_id": "c53863767484415b8432756f00ca4549", "version_major": 2, "version_minor": 0 }, "text/plain": [ - " 0%| | 0/6 [00:00\n", " \n", " 0\n", - " Country\n", - " participant_country\n", + " case_id\n", + " case_id\n", " \n", " \n", " 1\n", - " Gender\n", - " sex\n", + " age\n", + " age\n", " \n", " \n", " 2\n", - " FIGO_stage\n", - " tumor_stage_pathological\n", + " gender\n", + " sex\n", " \n", " \n", " 3\n", - " Path_Stage_Reg_Lymph_Nodes-pN\n", - " pathologic_staging_regional_lymph_nodes_pn\n", + " country\n", + " participant_country\n", " \n", " \n", " 4\n", - " tumor_Stage-Pathological\n", - " tumor_stage_pathological\n", + " smoking_history\n", + " tobacco_smoking_history\n", " \n", " \n", " 5\n", - " Tumor_Focality\n", + " smoke_age_start\n", + " age\n", + " \n", + " \n", + " 6\n", + " smoke_age_stop\n", + " age\n", + " \n", + " \n", + " 7\n", + " num_smoke_per_day\n", + " tobacco_smoking_history\n", + " \n", + " \n", + " 8\n", + " num_pack_years_sm\n", + " bmi\n", + " \n", + " \n", + " 9\n", + " smoking_second_hand\n", + " tobacco_smoking_history\n", + " \n", + " \n", + " 10\n", + " smoking_inferred\n", + " tobacco_smoking_history\n", + " \n", + " \n", + " 11\n", + " alcohol_consum\n", + " alcohol_consumption\n", + " \n", + " \n", + " 12\n", + " num_yrs_alc_con\n", + " Neoplastic_cellularity\n", + " \n", + " \n", + " 13\n", + " tumor_site_original\n", + " tumor_site\n", + " \n", + " \n", + " 14\n", + " tumor_site_curated\n", + " tumor_site\n", + " \n", + " \n", + " 15\n", " tumor_focality\n", + " tumor_focality\n", + " \n", + " \n", + " 16\n", + " tumor_size_cm\n", + " tumor_size_cm\n", + " \n", + " \n", + " 17\n", + " histologic_type\n", + " case_id\n", + " \n", + " \n", + " 18\n", + " histologic_grade\n", + " tumor_stage_pathological\n", + " \n", + " \n", + " 19\n", + " tumor_necrosis\n", + " tumor_necrosis\n", + " \n", + " \n", + " 20\n", + " patho_staging_pt\n", + " pathologic_staging_primary_tumor_pt\n", + " \n", + " \n", + " 21\n", + " patho_staging_pn\n", + " pathologic_staging_regional_lymph_nodes_pn\n", + " \n", + " \n", + " 22\n", + " clinic_staging_dist_metas\n", + " clinical_staging_distant_metastasis_cm\n", + " \n", + " \n", + " 23\n", + " tumor_stage\n", + " tumor_stage_pathological\n", + " \n", + " \n", + " 24\n", + " P16\n", + " Acinar_fraction\n", + " \n", + " \n", + " 25\n", + " HPV_inference\n", + " perineural_invasion\n", + " \n", + " \n", + " 26\n", + " NAT_pathology_review\n", + " Neoplastic_cellularity\n", + " \n", + " \n", + " 27\n", + " tumor_pathology_review\n", + " Stromal_fraction\n", + " \n", + " \n", + " 28\n", + " ESTIMATE_stromal_score\n", + " Stromal_fraction\n", + " \n", + " \n", + " 29\n", + " ESTIMATE_immune_score\n", + " Stromal_fraction\n", + " \n", + " \n", + " 30\n", + " CD3_IHC_count\n", + " Acinar_fraction\n", + " \n", + " \n", + " 31\n", + " stemness_score\n", + " Stromal_fraction\n", + " \n", + " \n", + " 32\n", + " mutation_count\n", + " bmi\n", + " \n", + " \n", + " 33\n", + " neoAntigen_count\n", + " Neoplastic_cellularity\n", + " \n", + " \n", + " 34\n", + " chr_instability_idx\n", + " case_id\n", + " \n", + " \n", + " 35\n", + " integrated_subtype\n", + " bmi\n", + " \n", + " \n", + " 36\n", + " transcriptomic_subtype\n", + " bmi\n", " \n", " \n", "\n", "" ], "text/plain": [ - " source target\n", - "0 Country participant_country\n", - "1 Gender sex\n", - "2 FIGO_stage tumor_stage_pathological\n", - "3 Path_Stage_Reg_Lymph_Nodes-pN pathologic_staging_regional_lymph_nodes_pn\n", - "4 tumor_Stage-Pathological tumor_stage_pathological\n", - "5 Tumor_Focality tumor_focality" + " source target\n", + "0 case_id case_id\n", + "1 age age\n", + "2 gender sex\n", + "3 country participant_country\n", + "4 smoking_history tobacco_smoking_history\n", + "5 smoke_age_start age\n", + "6 smoke_age_stop age\n", + "7 num_smoke_per_day tobacco_smoking_history\n", + "8 num_pack_years_sm bmi\n", + "9 smoking_second_hand tobacco_smoking_history\n", + "10 smoking_inferred tobacco_smoking_history\n", + "11 alcohol_consum alcohol_consumption\n", + "12 num_yrs_alc_con Neoplastic_cellularity\n", + "13 tumor_site_original tumor_site\n", + "14 tumor_site_curated tumor_site\n", + "15 tumor_focality tumor_focality\n", + "16 tumor_size_cm tumor_size_cm\n", + "17 histologic_type case_id\n", + "18 histologic_grade tumor_stage_pathological\n", + "19 tumor_necrosis tumor_necrosis\n", + "20 patho_staging_pt pathologic_staging_primary_tumor_pt\n", + "21 patho_staging_pn pathologic_staging_regional_lymph_nodes_pn\n", + "22 clinic_staging_dist_metas clinical_staging_distant_metastasis_cm\n", + "23 tumor_stage tumor_stage_pathological\n", + "24 P16 Acinar_fraction\n", + "25 HPV_inference perineural_invasion\n", + "26 NAT_pathology_review Neoplastic_cellularity\n", + "27 tumor_pathology_review Stromal_fraction\n", + "28 ESTIMATE_stromal_score Stromal_fraction\n", + "29 ESTIMATE_immune_score Stromal_fraction\n", + "30 CD3_IHC_count Acinar_fraction\n", + "31 stemness_score Stromal_fraction\n", + "32 mutation_count bmi\n", + "33 neoAntigen_count Neoplastic_cellularity\n", + "34 chr_instability_idx case_id\n", + "35 integrated_subtype bmi\n", + "36 transcriptomic_subtype bmi" ] }, "execution_count": 4, @@ -1115,6 +1541,8 @@ "\n", "# Print value matches\n", "for match in value_matches:\n", + " bdi.edit_match(match)\n", + " bdi.view_match(match)\n", " display(\n", " Markdown(\n", " f\"
**Source column:** {match.attrs['source']}
\"\n", @@ -1686,7 +2114,7 @@ "name": "python", "nbconvert_exporter": "python", "pygments_lexer": "ipython3", - "version": "3.9.5" + "version": "3.10.12" } }, "nbformat": 4, diff --git a/examples/getting-started copy.ipynb b/examples/getting-started copy.ipynb new file mode 100644 index 00000000..898d0281 --- /dev/null +++ b/examples/getting-started copy.ipynb @@ -0,0 +1,8483 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# Getting Started" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "## Data Harmonization with `bdikit`" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Data harmonization is the process of integrating and aligning data from different sources into a consistent format to ensure compatibility and interoperability across data analyses and systems. `bdikit` is a library the helps with key data harmonization steps:\n", + "- *Schema Mapping*: In this step, data from various sources are mapped to a unified schema or model. This involves identifying equivalent table columns and establishing relationships between disparate datasets.\n", + "- *Value Mapping (Data Standardization)*: This step involves converting data into a common format or structure, using consistent naming conventions, units, and coding systems to ensure uniformity.\n", + "\n", + "In this example, we describe how `bdikit` can be used to map a dataset from Dou et al. (https://pubmed.ncbi.nlm.nih.gov/37567170/) to the [GDC (Genomic Data Commons)](https://portal.gdc.cancer.gov/) standard data format.\n", + "\n", + "First, import the `bdikit` library." + ] + }, + { + "cell_type": "code", + "execution_count": 1, + "metadata": {}, + "outputs": [], + "source": [ + "import bdikit as bdi\n", + "import pandas as pd" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Next, we load the data using Pandas." + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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CountryHistologic_Grade_FIGOHistologic_typePath_Stage_Primary_Tumor-pTPath_Stage_Reg_Lymph_Nodes-pNClin_Stage_Dist_Mets-cMPath_Stage_Dist_Mets-pMtumor_Stage-PathologicalFIGO_stageBMIAgeRaceEthnicityGenderTumor_SiteTumor_FocalityTumor_Size_cm
0United StatesFIGO grade 1EndometrioidpT1a (FIGO IA)pN0cM0Staging IncompleteStage IIA38.8864.0WhiteNot-Hispanic or LatinoFemaleAnterior endometriumUnifocal2.9
1United StatesFIGO grade 1EndometrioidpT1a (FIGO IA)pNXcM0Staging IncompleteStage IVIA39.7658.0WhiteNot-Hispanic or LatinoFemalePosterior endometriumUnifocal3.5
2United StatesFIGO grade 2EndometrioidpT1a (FIGO IA)pN0cM0Staging IncompleteStage IIA51.1950.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal4.5
3NaNNaNCarcinosarcomaNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaN
4United StatesFIGO grade 2EndometrioidpT1a (FIGO IA)pNXcM0No pathologic evidence of distant metastasisStage IIA32.6975.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal3.5
5United StatesNaNSerouspT1a (FIGO IA)pNXcM0Staging IncompleteStage IIA20.2863.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal6.0
6United StatesFIGO grade 1EndometrioidpT1a (FIGO IA)pNXcM0Staging IncompleteStage IIA55.6750.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal4.5
7Other_specifyFIGO grade 2EndometrioidpT1a (FIGO IA)pNXcM0Staging IncompleteStage IIA25.6860.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal5.0
8United StatesNaNSerouspT3a (FIGO IIIA)pNXcM0Staging IncompleteStage IIIIIIA21.5783.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal4.0
9United StatesFIGO grade 1EndometrioidpT1 (FIGO I)pN0cM0Staging IncompleteStage IIA34.2669.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal5.2
\n", + "
" + ], + "text/plain": [ + " Country Histologic_Grade_FIGO Histologic_type \\\n", + "0 United States FIGO grade 1 Endometrioid \n", + "1 United States FIGO grade 1 Endometrioid \n", + "2 United States FIGO grade 2 Endometrioid \n", + "3 NaN NaN Carcinosarcoma \n", + "4 United States FIGO grade 2 Endometrioid \n", + "5 United States NaN Serous \n", + "6 United States FIGO grade 1 Endometrioid \n", + "7 Other_specify FIGO grade 2 Endometrioid \n", + "8 United States NaN Serous \n", + "9 United States FIGO grade 1 Endometrioid \n", + "\n", + " Path_Stage_Primary_Tumor-pT Path_Stage_Reg_Lymph_Nodes-pN \\\n", + "0 pT1a (FIGO IA) pN0 \n", + "1 pT1a (FIGO IA) pNX \n", + "2 pT1a (FIGO IA) pN0 \n", + "3 NaN NaN \n", + "4 pT1a (FIGO IA) pNX \n", + "5 pT1a (FIGO IA) pNX \n", + "6 pT1a (FIGO IA) pNX \n", + "7 pT1a (FIGO IA) pNX \n", + "8 pT3a (FIGO IIIA) pNX \n", + "9 pT1 (FIGO I) pN0 \n", + "\n", + " Clin_Stage_Dist_Mets-cM Path_Stage_Dist_Mets-pM \\\n", + "0 cM0 Staging Incomplete \n", + "1 cM0 Staging Incomplete \n", + "2 cM0 Staging Incomplete \n", + "3 NaN NaN \n", + "4 cM0 No pathologic evidence of distant metastasis \n", + "5 cM0 Staging Incomplete \n", + "6 cM0 Staging Incomplete \n", + "7 cM0 Staging Incomplete \n", + "8 cM0 Staging Incomplete \n", + "9 cM0 Staging Incomplete \n", + "\n", + " tumor_Stage-Pathological FIGO_stage BMI Age Race \\\n", + "0 Stage I IA 38.88 64.0 White \n", + "1 Stage IV IA 39.76 58.0 White \n", + "2 Stage I IA 51.19 50.0 White \n", + "3 NaN NaN NaN NaN NaN \n", + "4 Stage I IA 32.69 75.0 White \n", + "5 Stage I IA 20.28 63.0 White \n", + "6 Stage I IA 55.67 50.0 White \n", + "7 Stage I IA 25.68 60.0 White \n", + "8 Stage III IIIA 21.57 83.0 White \n", + "9 Stage I IA 34.26 69.0 White \n", + "\n", + " Ethnicity Gender Tumor_Site Tumor_Focality \\\n", + "0 Not-Hispanic or Latino Female Anterior endometrium Unifocal \n", + "1 Not-Hispanic or Latino Female Posterior endometrium Unifocal \n", + "2 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "3 NaN NaN NaN NaN \n", + "4 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "5 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "6 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "7 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "8 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "9 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "\n", + " Tumor_Size_cm \n", + "0 2.9 \n", + "1 3.5 \n", + "2 4.5 \n", + "3 NaN \n", + "4 3.5 \n", + "5 6.0 \n", + "6 4.5 \n", + "7 5.0 \n", + "8 4.0 \n", + "9 5.2 " + ] + }, + "execution_count": 2, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "dataset = pd.read_csv(\"./datasets/dou.csv\")\n", + "\n", + "# columns = [\n", + "# \"Country\",\n", + "# \"Path_Stage_Primary_Tumor-pT\",\n", + "# \"FIGO_stage\",\n", + "# \"Race\",\n", + "# \"Ethnicity\",\n", + "# \"Gender\",\n", + "# \"Tumor_Focality\",\n", + "# \"Tumor_Site\",\n", + "# ]\n", + "columns = [\n", + " \"Country\",\n", + " \"Path_Stage_Primary_Tumor-pT\",\n", + " \"Histologic_type\",\n", + " \"FIGO_stage\",\n", + " \"BMI\",\n", + " \"Age\",\n", + " \"Race\",\n", + " \"Ethnicity\",\n", + " \"Gender\",\n", + " \"Tumor_Focality\",\n", + " \"Tumor_Size_cm\",\n", + "]\n", + "# dataset = dataset[columns]\n", + "dataset.head(10)" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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CountryHistologic_Grade_FIGOHistologic_typePath_Stage_Primary_Tumor-pTPath_Stage_Reg_Lymph_Nodes-pNClin_Stage_Dist_Mets-cMPath_Stage_Dist_Mets-pMtumor_Stage-PathologicalFIGO_stageBMIAgeRaceEthnicityGenderTumor_SiteTumor_FocalityTumor_Size_cm
0United StatesFIGO grade 1EndometrioidpT1a (FIGO IA)pN0cM0Staging IncompleteStage IIA38.8864.0WhiteNot-Hispanic or LatinoFemaleAnterior endometriumUnifocal2.9
1United StatesFIGO grade 1EndometrioidpT1a (FIGO IA)pNXcM0Staging IncompleteStage IVIA39.7658.0WhiteNot-Hispanic or LatinoFemalePosterior endometriumUnifocal3.5
2United StatesFIGO grade 2EndometrioidpT1a (FIGO IA)pN0cM0Staging IncompleteStage IIA51.1950.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal4.5
3NaNNaNCarcinosarcomaNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaN
4United StatesFIGO grade 2EndometrioidpT1a (FIGO IA)pNXcM0No pathologic evidence of distant metastasisStage IIA32.6975.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal3.5
......................................................
99UkraineFIGO grade 3EndometrioidpT1a (FIGO IA)pNXcM0Staging IncompleteStage IIA29.4075.0NaNNaNFemaleOther, specifyUnifocal4.2
100UkraineFIGO grade 2EndometrioidpT2 (FIGO II)pN0cM0Staging IncompleteStage IIII35.4274.0NaNNaNFemaleOther, specifyUnifocal1.5
101United StatesNaNSerouspT2 (FIGO II)pN0Staging IncompleteStaging IncompleteStage IIII24.3285.0Black or African AmericanNot-Hispanic or LatinoFemaleOther, specifyUnifocal3.8
102UkraineNaNSerouspT1a (FIGO IA)pN0cM0Staging IncompleteStage IIA34.0670.0NaNNaNFemaleOther, specifyUnifocal5.0
103UkraineNaNSerousNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaN
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104 rows × 17 columns

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" + ], + "text/plain": [ + " Country Histologic_Grade_FIGO Histologic_type \\\n", + "0 United States FIGO grade 1 Endometrioid \n", + "1 United States FIGO grade 1 Endometrioid \n", + "2 United States FIGO grade 2 Endometrioid \n", + "3 NaN NaN Carcinosarcoma \n", + "4 United States FIGO grade 2 Endometrioid \n", + ".. ... ... ... \n", + "99 Ukraine FIGO grade 3 Endometrioid \n", + "100 Ukraine FIGO grade 2 Endometrioid \n", + "101 United States NaN Serous \n", + "102 Ukraine NaN Serous \n", + "103 Ukraine NaN Serous \n", + "\n", + " Path_Stage_Primary_Tumor-pT Path_Stage_Reg_Lymph_Nodes-pN \\\n", + "0 pT1a (FIGO IA) pN0 \n", + "1 pT1a (FIGO IA) pNX \n", + "2 pT1a (FIGO IA) pN0 \n", + "3 NaN NaN \n", + "4 pT1a (FIGO IA) pNX \n", + ".. ... ... \n", + "99 pT1a (FIGO IA) pNX \n", + "100 pT2 (FIGO II) pN0 \n", + "101 pT2 (FIGO II) pN0 \n", + "102 pT1a (FIGO IA) pN0 \n", + "103 NaN NaN \n", + "\n", + " Clin_Stage_Dist_Mets-cM Path_Stage_Dist_Mets-pM \\\n", + "0 cM0 Staging Incomplete \n", + "1 cM0 Staging Incomplete \n", + "2 cM0 Staging Incomplete \n", + "3 NaN NaN \n", + "4 cM0 No pathologic evidence of distant metastasis \n", + ".. ... ... \n", + "99 cM0 Staging Incomplete \n", + "100 cM0 Staging Incomplete \n", + "101 Staging Incomplete Staging Incomplete \n", + "102 cM0 Staging Incomplete \n", + "103 NaN NaN \n", + "\n", + " tumor_Stage-Pathological FIGO_stage BMI Age \\\n", + "0 Stage I IA 38.88 64.0 \n", + "1 Stage IV IA 39.76 58.0 \n", + "2 Stage I IA 51.19 50.0 \n", + "3 NaN NaN NaN NaN \n", + "4 Stage I IA 32.69 75.0 \n", + ".. ... ... ... ... \n", + "99 Stage I IA 29.40 75.0 \n", + "100 Stage II II 35.42 74.0 \n", + "101 Stage II II 24.32 85.0 \n", + "102 Stage I IA 34.06 70.0 \n", + "103 NaN NaN NaN NaN \n", + "\n", + " Race Ethnicity Gender \\\n", + "0 White Not-Hispanic or Latino Female \n", + "1 White Not-Hispanic or Latino Female \n", + "2 White Not-Hispanic or Latino Female \n", + "3 NaN NaN NaN \n", + "4 White Not-Hispanic or Latino Female \n", + ".. ... ... ... \n", + "99 NaN NaN Female \n", + "100 NaN NaN Female \n", + "101 Black or African American Not-Hispanic or Latino Female \n", + "102 NaN NaN Female \n", + "103 NaN NaN NaN \n", + "\n", + " Tumor_Site Tumor_Focality Tumor_Size_cm \n", + "0 Anterior endometrium Unifocal 2.9 \n", + "1 Posterior endometrium Unifocal 3.5 \n", + "2 Other, specify Unifocal 4.5 \n", + "3 NaN NaN NaN \n", + "4 Other, specify Unifocal 3.5 \n", + ".. ... ... ... \n", + "99 Other, specify Unifocal 4.2 \n", + "100 Other, specify Unifocal 1.5 \n", + "101 Other, specify Unifocal 3.8 \n", + "102 Other, specify Unifocal 5.0 \n", + "103 NaN NaN NaN \n", + "\n", + "[104 rows x 17 columns]" + ] + }, + "execution_count": 3, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "dataset" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Matching the table schema to GDC standard vocabulary\n", + "\n", + "`bdi-kit` offers a suite of functions to help with data harmonization tasks.\n", + "For instance, it can help with automatic discovery of one-to-one mappings between the columns in the input (source) dataset and a target dataset schema. The target schema can be either another table or a standard data vocabulary such as the GDC (Genomic Data Commons).\n", + "\n", + "To achieve this using `bdi-kit`, we can use the `match_schema()` function to match columns to the GDC vocabulary schema as follows." + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "Some weights of RobertaModel were not initialized from the model checkpoint at roberta-base and are newly initialized: ['roberta.pooler.dense.bias', 'roberta.pooler.dense.weight']\n", + "You should probably TRAIN this model on a down-stream task to be able to use it for predictions and inference.\n", + " 0%| | 0/11 [00:00\n", + "\n", + "\n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + "
sourcetarget
0Countryrace
1Path_Stage_Primary_Tumor-pTajcc_pathologic_t
2Histologic_typeprimary_diagnosis
3FIGO_stagefigo_stage
4BMIaverage_base_quality
5Ageage_at_last_exposure
6Racerace
7Ethnicityethnicity
8Genderprimary_site
9Tumor_Focalitytumor_focality
10Tumor_Size_cmcircumferential_resection_margin
\n", + "" + ], + "text/plain": [ + " source target\n", + "0 Country race\n", + "1 Path_Stage_Primary_Tumor-pT ajcc_pathologic_t\n", + "2 Histologic_type primary_diagnosis\n", + "3 FIGO_stage figo_stage\n", + "4 BMI average_base_quality\n", + "5 Age age_at_last_exposure\n", + "6 Race race\n", + "7 Ethnicity ethnicity\n", + "8 Gender primary_site\n", + "9 Tumor_Focality tumor_focality\n", + "10 Tumor_Size_cm circumferential_resection_margin" + ] + }, + "execution_count": 4, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "column_mappings = bdi.match_schema(dataset[columns], target=\"gdc\", method=\"two_phase\")\n", + "column_mappings" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Generating a harmonized table\n", + "\n", + "After discovering a schema mapping, we can generate a new table (DataFrame) using the new column names from the GDC standard vocabulary.\n", + "\n", + "To do so using `bdi-kit`, we can use the function `materialize_mapping()` as follows. Note that the column headers have been renamed to the target schema." + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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country_of_birthhistory_of_tumor_typefigo_stageaverage_base_qualityage_at_diagnosisraceethnicitygendertumor_focalitytumor_width_measurementtumor_level_prostate
0United StatesEndometrioidIA38.8864.0WhiteNot-Hispanic or LatinoFemaleUnifocal2.9Anterior endometrium
1United StatesEndometrioidIA39.7658.0WhiteNot-Hispanic or LatinoFemaleUnifocal3.5Posterior endometrium
2United StatesEndometrioidIA51.1950.0WhiteNot-Hispanic or LatinoFemaleUnifocal4.5Other, specify
3NaNCarcinosarcomaNaNNaNNaNNaNNaNNaNNaNNaNNaN
4United StatesEndometrioidIA32.6975.0WhiteNot-Hispanic or LatinoFemaleUnifocal3.5Other, specify
....................................
99UkraineEndometrioidIA29.4075.0NaNNaNFemaleUnifocal4.2Other, specify
100UkraineEndometrioidII35.4274.0NaNNaNFemaleUnifocal1.5Other, specify
101United StatesSerousII24.3285.0Black or African AmericanNot-Hispanic or LatinoFemaleUnifocal3.8Other, specify
102UkraineSerousIA34.0670.0NaNNaNFemaleUnifocal5.0Other, specify
103UkraineSerousNaNNaNNaNNaNNaNNaNNaNNaNNaN
\n", + "

104 rows × 11 columns

\n", + "
" + ], + "text/plain": [ + " country_of_birth history_of_tumor_type figo_stage average_base_quality \\\n", + "0 United States Endometrioid IA 38.88 \n", + "1 United States Endometrioid IA 39.76 \n", + "2 United States Endometrioid IA 51.19 \n", + "3 NaN Carcinosarcoma NaN NaN \n", + "4 United States Endometrioid IA 32.69 \n", + ".. ... ... ... ... \n", + "99 Ukraine Endometrioid IA 29.40 \n", + "100 Ukraine Endometrioid II 35.42 \n", + "101 United States Serous II 24.32 \n", + "102 Ukraine Serous IA 34.06 \n", + "103 Ukraine Serous NaN NaN \n", + "\n", + " age_at_diagnosis race ethnicity \\\n", + "0 64.0 White Not-Hispanic or Latino \n", + "1 58.0 White Not-Hispanic or Latino \n", + "2 50.0 White Not-Hispanic or Latino \n", + "3 NaN NaN NaN \n", + "4 75.0 White Not-Hispanic or Latino \n", + ".. ... ... ... \n", + "99 75.0 NaN NaN \n", + "100 74.0 NaN NaN \n", + "101 85.0 Black or African American Not-Hispanic or Latino \n", + "102 70.0 NaN NaN \n", + "103 NaN NaN NaN \n", + "\n", + " gender tumor_focality tumor_width_measurement tumor_level_prostate \n", + "0 Female Unifocal 2.9 Anterior endometrium \n", + "1 Female Unifocal 3.5 Posterior endometrium \n", + "2 Female Unifocal 4.5 Other, specify \n", + "3 NaN NaN NaN NaN \n", + "4 Female Unifocal 3.5 Other, specify \n", + ".. ... ... ... ... \n", + "99 Female Unifocal 4.2 Other, specify \n", + "100 Female Unifocal 1.5 Other, specify \n", + "101 Female Unifocal 3.8 Other, specify \n", + "102 Female Unifocal 5.0 Other, specify \n", + "103 NaN NaN NaN NaN \n", + "\n", + "[104 rows x 11 columns]" + ] + }, + "execution_count": 4, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.materialize_mapping(dataset, column_mappings)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Generating a harmonized table with value mappings\n", + "\n", + "`bdi-kit` can also help with translation of the values from the source table to the target standard format.\n", + "\n", + "To this end, `bdi-kit` provides the function `match_values()` that automatically creates value mappings for each string column.\n", + "The output of `match_values()` can be fed to `materialize_mapping()` which materialized the final target using both schema and value mappings." + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": {}, + "outputs": [], + "source": [ + "value_mappings = bdi.match_values(dataset, column_mapping=column_mappings, target=\"gdc\", method=\"tfidf\")\n", + "bdi.materialize_mapping(dataset, value_mappings)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "## Verifying and Correcting Automatic Mappings" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Verifying the schema mappings\n", + "\n", + "Sometimes the mappings generated automatically may be incorrect or you may to want verify them individually.\n", + "To verify the suggested column mappings, `bdi-kit` offers additional APIs to visualize the data and make any modifications when necessary. \n", + "\n", + "For this example, we will use the column `Histologic_type`. We can start by exploring the columns most similar to `Histologic_type`. \n", + "\n", + "For this, we can use the `top_matches()` function. Here, we notice that `primary_diagnosis` could be a potential target column.\n" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": {}, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "Some weights of RobertaModel were not initialized from the model checkpoint at roberta-base and are newly initialized: ['roberta.pooler.dense.bias', 'roberta.pooler.dense.weight']\n", + "You should probably TRAIN this model on a down-stream task to be able to use it for predictions and inference.\n", + "100%|██████████| 1/1 [00:00<00:00, 17.62it/s]\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Table features extracted from 1 columns\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "100%|██████████| 734/734 [00:55<00:00, 13.25it/s]" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Table features extracted from 734 columns\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "\n" + ] + }, + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Histologic_typedisease_type0.539168
1Histologic_typesample_type0.530217
2Histologic_typeroots0.525866
3Histologic_typehistory_of_tumor_type0.524959
4Histologic_typeadditional_pathology_findings0.517125
5Histologic_typespecimen_type0.511611
6Histologic_typemorphologic_architectural_pattern0.482257
7Histologic_typehistone_variant0.478656
8Histologic_typeviral_hepatitis_serologies0.471346
9Histologic_typechromosome0.471309
10Histologic_typeanalyte_type_id0.450211
11Histologic_typecomposition0.446170
12Histologic_typedescribed_cases0.445148
13Histologic_typepathology_details0.434320
14Histologic_typeantigen0.432611
15Histologic_typepathology_reports0.429676
16Histologic_typecog_rhabdomyosarcoma_risk_group0.420320
17Histologic_typebiospecimen_type0.420141
18Histologic_typeanalyte_type0.403565
19Histologic_typesingle_cell_library0.403199
20Histologic_typelaboratory_test0.399581
21Histologic_typeslide_images0.398477
22Histologic_typetumor_descriptor0.396314
23Histologic_typesample_type_id0.391940
24Histologic_typerelationship_primary_diagnosis0.391895
25Histologic_typeicd_10_code0.388311
26Histologic_typestain_type0.385822
27Histologic_typehistone_family0.385273
28Histologic_typepathogenicity0.383606
29Histologic_typecontiguous_organ_invaded0.383036
30Histologic_typeaids_risk_factors0.382602
31Histologic_typeicd_100.375303
32Histologic_typebiospecimen_anatomic_site0.372609
33Histologic_typeprimary_diagnosis0.371001
34Histologic_typedysplasia_type0.369152
35Histologic_typetissue_type0.367687
36Histologic_typegene_symbol0.366179
37Histologic_typesarcomatoid_present0.354912
38Histologic_typepapillary_renal_cell_type0.351789
39Histologic_typehysterectomy_type0.348222
\n", + "
" + ], + "text/plain": [ + " source target similarity\n", + "0 Histologic_type disease_type 0.539168\n", + "1 Histologic_type sample_type 0.530217\n", + "2 Histologic_type roots 0.525866\n", + "3 Histologic_type history_of_tumor_type 0.524959\n", + "4 Histologic_type additional_pathology_findings 0.517125\n", + "5 Histologic_type specimen_type 0.511611\n", + "6 Histologic_type morphologic_architectural_pattern 0.482257\n", + "7 Histologic_type histone_variant 0.478656\n", + "8 Histologic_type viral_hepatitis_serologies 0.471346\n", + "9 Histologic_type chromosome 0.471309\n", + "10 Histologic_type analyte_type_id 0.450211\n", + "11 Histologic_type composition 0.446170\n", + "12 Histologic_type described_cases 0.445148\n", + "13 Histologic_type pathology_details 0.434320\n", + "14 Histologic_type antigen 0.432611\n", + "15 Histologic_type pathology_reports 0.429676\n", + "16 Histologic_type cog_rhabdomyosarcoma_risk_group 0.420320\n", + "17 Histologic_type biospecimen_type 0.420141\n", + "18 Histologic_type analyte_type 0.403565\n", + "19 Histologic_type single_cell_library 0.403199\n", + "20 Histologic_type laboratory_test 0.399581\n", + "21 Histologic_type slide_images 0.398477\n", + "22 Histologic_type tumor_descriptor 0.396314\n", + "23 Histologic_type sample_type_id 0.391940\n", + "24 Histologic_type relationship_primary_diagnosis 0.391895\n", + "25 Histologic_type icd_10_code 0.388311\n", + "26 Histologic_type stain_type 0.385822\n", + "27 Histologic_type histone_family 0.385273\n", + "28 Histologic_type pathogenicity 0.383606\n", + "29 Histologic_type contiguous_organ_invaded 0.383036\n", + "30 Histologic_type aids_risk_factors 0.382602\n", + "31 Histologic_type icd_10 0.375303\n", + "32 Histologic_type biospecimen_anatomic_site 0.372609\n", + "33 Histologic_type primary_diagnosis 0.371001\n", + "34 Histologic_type dysplasia_type 0.369152\n", + "35 Histologic_type tissue_type 0.367687\n", + "36 Histologic_type gene_symbol 0.366179\n", + "37 Histologic_type sarcomatoid_present 0.354912\n", + "38 Histologic_type papillary_renal_cell_type 0.351789\n", + "39 Histologic_type hysterectomy_type 0.348222" + ] + }, + "execution_count": 6, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "hist_type_matches = bdi.top_matches(dataset, columns=[\"Histologic_type\"], target=\"gdc\", top_k=40)\n", + "hist_type_matches" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Viewing the column domains\n", + "\n", + "To verify that `primary_diagnosis` is a good target column, we view and compare the domains of each column using the `preview_domain()` function. For the source table, it returns the list of unique values in the source column. For the GDC target, it returns the list of unique valid values that a column can have.\n", + "\n", + "Here we see that the values seem to be related." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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value_name
0Endometrioid
1Carcinosarcoma
2Serous
3Clear cell
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" + ], + "text/plain": [ + " value_name\n", + "0 Endometrioid\n", + "1 Carcinosarcoma\n", + "2 Serous\n", + "3 Clear cell" + ] + }, + "execution_count": 7, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.preview_domain(dataset, \"Histologic_type\")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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value_namevalue_descriptioncolumn_description
0Abdominal desmoidAn insidious poorly circumscribed neoplasm ari...Text term used to describe the patient's histo...
1Abdominal fibromatosisAn insidious poorly circumscribed neoplasm ari...
2Achromic nevusA benign nevus characterized by the absence of...
3Acidophil adenocarcinomaA malignant epithelial neoplasm of the anterio...
4Acidophil adenomaAn epithelial neoplasm of the anterior pituita...
............
2620Wolffian duct tumorAn epithelial neoplasm of the female reproduct...
2621XanthofibromaA benign neoplasm composed of fibroblastic spi...
2622Yolk sac tumorA non-seminomatous malignant germ cell tumor c...
2623UnknownNot known, not observed, not recorded, or refu...
2624Not ReportedNot provided or available.
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2625 rows × 3 columns

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" + ], + "text/plain": [ + " value_name \\\n", + "0 Abdominal desmoid \n", + "1 Abdominal fibromatosis \n", + "2 Achromic nevus \n", + "3 Acidophil adenocarcinoma \n", + "4 Acidophil adenoma \n", + "... ... \n", + "2620 Wolffian duct tumor \n", + "2621 Xanthofibroma \n", + "2622 Yolk sac tumor \n", + "2623 Unknown \n", + "2624 Not Reported \n", + "\n", + " value_description \\\n", + "0 An insidious poorly circumscribed neoplasm ari... \n", + "1 An insidious poorly circumscribed neoplasm ari... \n", + "2 A benign nevus characterized by the absence of... \n", + "3 A malignant epithelial neoplasm of the anterio... \n", + "4 An epithelial neoplasm of the anterior pituita... \n", + "... ... \n", + "2620 An epithelial neoplasm of the female reproduct... \n", + "2621 A benign neoplasm composed of fibroblastic spi... \n", + "2622 A non-seminomatous malignant germ cell tumor c... \n", + "2623 Not known, not observed, not recorded, or refu... \n", + "2624 Not provided or available. \n", + "\n", + " column_description \n", + "0 Text term used to describe the patient's histo... \n", + "1 \n", + "2 \n", + "3 \n", + "4 \n", + "... ... \n", + "2620 \n", + "2621 \n", + "2622 \n", + "2623 \n", + "2624 \n", + "\n", + "[2625 rows x 3 columns]" + ] + }, + "execution_count": 8, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.preview_domain(\"gdc\", \"primary_diagnosis\")" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Since `primary_diagnosis` looks like a correct match for `Histologic_type`, we can modify the `column_mappings` variable directly." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetarget
0Countrycountry_of_birth
1Histologic_typeprimary_diagnosis
2FIGO_stageirs_stage
3BMIage_at_diagnosis
4Ageweight
5Racerace
6Ethnicityethnicity
7Gendergender
8Tumor_Focalitytumor_focality
9Tumor_Size_cmtumor_depth
10Tumor_Sitetumor_shape
\n", + "
" + ], + "text/plain": [ + " source target\n", + "0 Country country_of_birth\n", + "1 Histologic_type primary_diagnosis\n", + "2 FIGO_stage irs_stage\n", + "3 BMI age_at_diagnosis\n", + "4 Age weight\n", + "5 Race race\n", + "6 Ethnicity ethnicity\n", + "7 Gender gender\n", + "8 Tumor_Focality tumor_focality\n", + "9 Tumor_Size_cm tumor_depth\n", + "10 Tumor_Site tumor_shape" + ] + }, + "execution_count": 9, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "column_mappings.loc[column_mappings[\"source\"] == \"Histologic_type\", \"target\"] = \"primary_diagnosis\"\n", + "column_mappings" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Finding correct value mappings\n", + "\n", + "After finding the correct column, we need to find appropriate value mappings. \n", + "Using `match_values()`, we can inspect what the possible value mappings for this would look like after the harmonization.\n", + "\n", + "`bdi-kit` implements multiple methods for value mapping discovery, including:\n", + "\n", + " - `edit_distance` - Computes value similarities using Levenstein's edit distance measure.\n", + " - `tfidf` - A method based on tf-idf importance weighting computed over charcter n-grams.\n", + " - `embeddings` - Uses BERT word embeddings to compute \"semantic similarity\" between the values.\n", + "\n", + "To specify a value mapping approach, we can pass the `method` parameter." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0CarcinosarcomaCarcinosarcoma, NOS0.848485
1Clear cellClear cell adenoma0.714286
2EndometrioidStromal endometriosis0.666667
3SerousNeuronevus0.625000
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Carcinosarcoma Carcinosarcoma, NOS 0.848485\n", + "1 Clear cell Clear cell adenoma 0.714286\n", + "2 Endometrioid Stromal endometriosis 0.666667\n", + "3 Serous Neuronevus 0.625000" + ] + }, + "execution_count": 10, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.match_values(\n", + " dataset, column_mapping=(\"Histologic_type\", \"primary_diagnosis\"), target=\"gdc\", method=\"edit_distance\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0CarcinosarcomaCarcinosarcoma, NOS0.969
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2Clear cellClear cell adenoma0.853
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sourcetargetsimilarity
0CarcinosarcomaCarcinofibroma0.919
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2Clear cellClear cell carcinoma0.760
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Carcinosarcoma Carcinofibroma 0.919\n", + "1 Endometrioid Endometrioid cystadenocarcinoma 0.810\n", + "2 Clear cell Clear cell carcinoma 0.760\n", + "3 Serous Serous cystoma 0.661" + ] + }, + "execution_count": 12, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.match_values(\n", + " dataset, column_mapping=(\"Histologic_type\", \"primary_diagnosis\"), target=\"gdc\", method=\"embedding\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetarget
0CarcinosarcomaCarcinosarcoma, NOS
1Clear cellClear cell adenocarcinoma, NOS
2EndometrioidEndometrioid carcinoma
3SerousSerous cystadenocarcinoma
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" + ], + "text/plain": [ + " source target\n", + "0 Carcinosarcoma Carcinosarcoma, NOS\n", + "1 Clear cell Clear cell adenocarcinoma, NOS\n", + "2 Endometrioid Endometrioid carcinoma\n", + "3 Serous Serous cystadenocarcinoma" + ] + }, + "execution_count": 13, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "hist_type_vmap = pd.DataFrame(\n", + " columns=[\"source\", \"target\"],\n", + " data=[\n", + " (\"Carcinosarcoma\", \"Carcinosarcoma, NOS\"),\n", + " (\"Clear cell\", \"Clear cell adenocarcinoma, NOS\"),\n", + " (\"Endometrioid\", \"Endometrioid carcinoma\"),\n", + " (\"Serous\", \"Serous cystadenocarcinoma\"),\n", + " ],\n", + ")\n", + "hist_type_vmap" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Verifying multiple value mappings at once\n", + "\n", + "Besides verifying value mappings individually, you can also do it for all column mappings at once." + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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6Histologic_typemorphologic_architectural_pattern0.482257
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8Histologic_typeviral_hepatitis_serologies0.471346
9Histologic_typechromosome0.471309
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sourcetargetsimilarity
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1EndometrioidEndometrioid adenoma, NOS0.897
2Clear cellClear cell adenoma0.853
3SerousSerous carcinoma, NOS0.755
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Carcinosarcoma Carcinosarcoma, NOS 0.969\n", + "1 Endometrioid Endometrioid adenoma, NOS 0.897\n", + "2 Clear cell Clear cell adenoma 0.853\n", + "3 Serous Serous carcinoma, NOS 0.755" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "mappings = bdi.match_values(\n", + " dataset,\n", + " column_mapping=hist_type_matches.head(34),\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + " # default_missing=None\n", + ")\n", + "\n", + "for mapping in mappings:\n", + " mapping.attrs['default_missing'] = \"___\"\n", + " print(f\"{mapping.attrs['source']} => {mapping.attrs['target']} (coverage: {mapping.attrs['coverage']:.2%})\")\n", + " display(mapping)" + ] + }, + { + "cell_type": "code", + "execution_count": 13, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0CarcinosarcomaCarcinosarcoma, NOS0.969
1EndometrioidEndometrioid adenoma, NOS0.897
2Clear cellClear cell adenoma0.853
3SerousSerous carcinoma, NOS0.755
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Carcinosarcoma Carcinosarcoma, NOS 0.969\n", + "1 Endometrioid Endometrioid adenoma, NOS 0.897\n", + "2 Clear cell Clear cell adenoma 0.853\n", + "3 Serous Serous carcinoma, NOS 0.755" + ] + }, + "execution_count": 13, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "import numpy as np\n", + "scores = [\n", + " np.sum(m[\"similarity\"])\n", + " for m in mappings\n", + "]\n", + "scores\n", + "sorted_mappings = [m for _, m in sorted(zip(scores, mappings), key=lambda it: it[0], reverse=True)]\n", + "sorted_mappings[0]" + ] + }, + { + "cell_type": "code", + "execution_count": 15, + "metadata": {}, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "Some weights of RobertaModel were not initialized from the model checkpoint at roberta-base and are newly initialized: ['roberta.pooler.dense.bias', 'roberta.pooler.dense.weight']\n", + "You should probably TRAIN this model on a down-stream task to be able to use it for predictions and inference.\n", + "100%|██████████| 1/1 [00:00<00:00, 11.98it/s]\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Table features extracted from 1 columns\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "100%|██████████| 734/734 [00:52<00:00, 13.92it/s]" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Table features extracted from 734 columns\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "\n" + ] + }, + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
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1Path_Stage_Primary_Tumor-pTajcc_pathologic_t0.660834
2Path_Stage_Primary_Tumor-pTensat_pathologic_t0.660739
3Path_Stage_Primary_Tumor-pTuicc_clinical_t0.645708
4Path_Stage_Primary_Tumor-pTajcc_clinical_t0.592968
5Path_Stage_Primary_Tumor-pTextrathyroid_extension0.589977
6Path_Stage_Primary_Tumor-pTuicc_pathologic_stage0.584754
7Path_Stage_Primary_Tumor-pTsomatic_mutation_indexes0.571665
8Path_Stage_Primary_Tumor-pTajcc_pathologic_stage0.563254
9Path_Stage_Primary_Tumor-pTannotated_somatic_mutations0.563235
10Path_Stage_Primary_Tumor-pTmasked_somatic_mutations0.536071
11Path_Stage_Primary_Tumor-pTfigo_stage0.535757
12Path_Stage_Primary_Tumor-pTtumor_level_prostate0.525700
13Path_Stage_Primary_Tumor-pTensat_pathologic_stage0.524734
14Path_Stage_Primary_Tumor-pTuicc_clinical_stage0.512399
15Path_Stage_Primary_Tumor-pTtumor_grade_category0.510672
16Path_Stage_Primary_Tumor-pTajcc_clinical_stage0.501770
17Path_Stage_Primary_Tumor-pTinss_stage0.477118
18Path_Stage_Primary_Tumor-pTadapter_sequence0.473948
19Path_Stage_Primary_Tumor-pTmargin_distance0.438898
20Path_Stage_Primary_Tumor-pTmasaoka_stage0.434978
21Path_Stage_Primary_Tumor-pTenneking_msts_tumor_site0.433908
22Path_Stage_Primary_Tumor-pTtumor_regression_grade0.421245
23Path_Stage_Primary_Tumor-pTtumor_grade0.401092
24Path_Stage_Primary_Tumor-pTaggregated_somatic_mutations0.397975
25Path_Stage_Primary_Tumor-pTfastq_name0.391604
26Path_Stage_Primary_Tumor-pTroute_of_administration0.388670
27Path_Stage_Primary_Tumor-pTdistance_normal_to_tumor0.381779
28Path_Stage_Primary_Tumor-pTtarget_capture_kit_catalog_number0.378923
29Path_Stage_Primary_Tumor-pTaa_change0.376404
30Path_Stage_Primary_Tumor-pTsubmitted_aligned_reads_files0.375468
31Path_Stage_Primary_Tumor-pTshortest_dimension0.371787
32Path_Stage_Primary_Tumor-pTsubmitted_genomic_profiles0.371026
33Path_Stage_Primary_Tumor-pTbest_overall_response0.366447
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36Path_Stage_Primary_Tumor-pTzone_of_origin_prostate0.360281
37Path_Stage_Primary_Tumor-pTsimple_germline_variations0.358423
38Path_Stage_Primary_Tumor-pTadverse_event_grade0.357383
39Path_Stage_Primary_Tumor-pTsimple_somatic_mutations0.353099
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sourcetargetsimilarity
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sourcetargetsimilarity
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" + ], + "text/plain": [ + " source target similarity\n", + "0 pT3b (FIGO IIIB) Stage IIIB 0.532\n", + "1 pT3a (FIGO IIIA) Stage IIIA 0.478\n", + "2 nan Unknown 0.379\n", + "3 pT1b (FIGO IB) Stage IB 0.339\n", + "4 pT2 (FIGO II) Stage III 0.265\n", + "5 pT1a (FIGO IA) None NaN\n", + "6 pT1 (FIGO I) None NaN" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "mappings = bdi.match_values(\n", + " dataset,\n", + " column_mapping=path_stage_matches.head(10),\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + " # default_missing=None\n", + ")\n", + "\n", + "for mapping in mappings:\n", + " mapping.attrs['default_missing'] = \"___\"\n", + " print(f\"{mapping.attrs['source']} => {mapping.attrs['target']} (coverage: {mapping.attrs['coverage']:.2%})\")\n", + " display(mapping)" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "metadata": {}, + "outputs": [ + { + "ename": "NameError", + "evalue": "name 'mappings' is not defined", + "output_type": "error", + "traceback": [ + "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m", + "\u001b[0;31mNameError\u001b[0m Traceback (most recent call last)", + "Cell \u001b[0;32mIn[8], line 4\u001b[0m\n\u001b[1;32m 1\u001b[0m \u001b[38;5;28;01mimport\u001b[39;00m \u001b[38;5;21;01mnumpy\u001b[39;00m \u001b[38;5;28;01mas\u001b[39;00m \u001b[38;5;21;01mnp\u001b[39;00m\n\u001b[1;32m 2\u001b[0m scores \u001b[38;5;241m=\u001b[39m [\n\u001b[1;32m 3\u001b[0m np\u001b[38;5;241m.\u001b[39msum(m[\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124msimilarity\u001b[39m\u001b[38;5;124m\"\u001b[39m])\n\u001b[0;32m----> 4\u001b[0m \u001b[38;5;28;01mfor\u001b[39;00m m \u001b[38;5;129;01min\u001b[39;00m \u001b[43mmappings\u001b[49m\n\u001b[1;32m 5\u001b[0m ]\n\u001b[1;32m 6\u001b[0m scores\n\u001b[1;32m 7\u001b[0m sorted_mappings \u001b[38;5;241m=\u001b[39m [m \u001b[38;5;28;01mfor\u001b[39;00m _, m \u001b[38;5;129;01min\u001b[39;00m \u001b[38;5;28msorted\u001b[39m(\u001b[38;5;28mzip\u001b[39m(scores, mappings), key\u001b[38;5;241m=\u001b[39m\u001b[38;5;28;01mlambda\u001b[39;00m it: it[\u001b[38;5;241m0\u001b[39m], reverse\u001b[38;5;241m=\u001b[39m\u001b[38;5;28;01mTrue\u001b[39;00m)]\n", + "\u001b[0;31mNameError\u001b[0m: name 'mappings' is not defined" + ] + } + ], + "source": [ + "import numpy as np\n", + "scores = [\n", + " np.sum(m[\"similarity\"])\n", + " for m in mappings\n", + "]\n", + "scores\n", + "sorted_mappings = [m for _, m in sorted(zip(scores, mappings), key=lambda it: it[0], reverse=True)]\n", + "print(scores[:2])\n", + "print(sorted_mappings[1].attrs[\"target\"])\n", + "sorted_mappings[1]" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": {}, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "Some weights of RobertaModel were not initialized from the model checkpoint at roberta-base and are newly initialized: ['roberta.pooler.dense.bias', 'roberta.pooler.dense.weight']\n", + "You should probably TRAIN this model on a down-stream task to be able to use it for predictions and inference.\n", + "100%|██████████| 1/1 [00:00<00:00, 17.54it/s]\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Table features extracted from 1 columns\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "100%|██████████| 734/734 [00:48<00:00, 15.13it/s]" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Table features extracted from 734 columns\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "\n" + ] + }, + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
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1Countrycountry_of_residence_at_enrollment0.419452
2Countryoct_embedded0.371549
3Countryrace0.352190
4Countrysubmission_enabled0.325194
5Countryzone_of_origin_prostate0.281882
6Countryis_legacy0.279952
7Countryreleased0.271991
8Countrynon_nodal_regional_disease0.268099
9Countryperineural_invasion_present0.225525
10Countryethnicity0.217912
11Countryconsent_type0.210355
12Countryrequest_submission0.208036
13Countryreleasable0.207206
14Countryproject_id0.204526
15Countryoverrepresented_sequences0.203413
16Countryyear_of_diagnosis0.192407
17Countrystatus0.189337
18Countryulceration_indicator0.188119
19Countryvascular_invasion_present0.188106
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" + ], + "text/plain": [ + " source target similarity\n", + "0 United States Not Reported 0.325\n", + "1 nan None NaN\n", + "2 Ukraine None NaN\n", + "3 Poland None NaN\n", + "4 Other_specify None NaN" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "mappings = bdi.match_values(\n", + " dataset,\n", + " column_mapping=country_matches,\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + " # default_missing=None\n", + ")\n", + "\n", + "for mapping in mappings:\n", + " print(f\"{mapping.attrs['source']} => {mapping.attrs['target']} (coverage: {mapping.attrs['coverage']:.2%})\")\n", + " display(mapping)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Fixing remaining value mappings\n", + "\n", + "We need fix a few value mappings:\n", + "- Race\n", + "- Ethnicity\n", + "- Tumor_Site\n", + "\n", + "For race, we need to fix: `nan` -> `american indian or alaska native`." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Whitewhite1.000
1Asianasian1.000
2Not Reportednot reported1.000
3Black or African Americanblack or african american1.000
4nanamerican indian or alaska native0.359
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" + ], + "text/plain": [ + " source target similarity\n", + "0 White white 1.000\n", + "1 Asian asian 1.000\n", + "2 Not Reported not reported 1.000\n", + "3 Black or African American black or african american 1.000\n", + "4 nan american indian or alaska native 0.359" + ] + }, + "execution_count": 15, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "race_vmap = bdi.match_values(\n", + " dataset,\n", + " column_mapping=(\"Race\", \"race\"),\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + ")\n", + "race_vmap" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Whitewhite1.0
1Asianasian1.0
2Not Reportednot reported1.0
3Black or African Americanblack or african american1.0
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" + ], + "text/plain": [ + " source target similarity\n", + "0 White white 1.0\n", + "1 Asian asian 1.0\n", + "2 Not Reported not reported 1.0\n", + "3 Black or African American black or african american 1.0" + ] + }, + "execution_count": 16, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "race_vmap = race_vmap[race_vmap[\"similarity\"] >= 1.0]\n", + "race_vmap" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "For `Ethnicity`, we need to fix: `Not reported` -> `not hispanic or latino`." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Hispanic or Latinohispanic or latino1.000
1Not-Hispanic or Latinonot hispanic or latino0.935
2Not reportednot hispanic or latino0.268
3nanNoneNaN
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Hispanic or Latino hispanic or latino 1.000\n", + "1 Not-Hispanic or Latino not hispanic or latino 0.935\n", + "2 Not reported not hispanic or latino 0.268\n", + "3 nan None NaN" + ] + }, + "execution_count": 17, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "ethinicity_vmap = bdi.match_values(\n", + " dataset,\n", + " column_mapping=(\"Ethnicity\", \"ethnicity\"),\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + ")\n", + "ethinicity_vmap\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Hispanic or Latinohispanic or latino1.000
1Not-Hispanic or Latinonot hispanic or latino0.935
\n", + "
" + ], + "text/plain": [ + " source target similarity\n", + "0 Hispanic or Latino hispanic or latino 1.000\n", + "1 Not-Hispanic or Latino not hispanic or latino 0.935" + ] + }, + "execution_count": 18, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "ethinicity_vmap = ethinicity_vmap[ethinicity_vmap[\"similarity\"] > 0.9]\n", + "ethinicity_vmap" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "For `Tumor_Site`, given that this dataset is about endometrial cancer, all values must be mapped to \"Endometrium\". So instead of fixing each mapping individually, we will write a custom function that returns \"Endometrium\" regardless of the input value. Later, we will show how to use this function to transform the dataset." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Anterior endometriumEndometrium0.852
1Posterior endometriumEndometrium0.823
2Other, specifyOther specified parts of pancreas0.543
3nanAnal canal0.301
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Anterior endometrium Endometrium 0.852\n", + "1 Posterior endometrium Endometrium 0.823\n", + "2 Other, specify Other specified parts of pancreas 0.543\n", + "3 nan Anal canal 0.301" + ] + }, + "execution_count": 19, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.match_values(\n", + " dataset, column_mapping=(\"Tumor_Site\", \"tissue_or_organ_of_origin\"), target=\"gdc\", method=\"tfidf\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "# Custom mapping function that will be used to map the values of the 'Tumor_Site' column\n", + "def map_tumor_site(source_value):\n", + " return \"Endometrium\"" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Combining custom user mappings with suggested mappings\n", + "\n", + "Before generating a final harmonized dataset, we can combine the automatically generated value mappings with the fixed mappings provided by the user. To do so, we use `bdi.merge_mappings()` functions, which take a list of mappings (e.g., generated automatically) and a list of \"user-defined mapping overrides\" that will be combined with the first list of mappings and will take precedence whenever they conflict.\n", + "\n", + "In our example below, all mappings specified in the variable `user_mappings` will override the mappings in `value_mappings` generated by the `bdi.match_values()` function." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "from math import ceil\n", + "\n", + "user_mappings = [\n", + " {\n", + " # When no mapping is need, specifying the source and target is enough\n", + " \"source\": \"BMI\",\n", + " \"target\": \"bmi\",\n", + " },\n", + " {\n", + " \"source\": \"Tumor_Size_cm\",\n", + " \"target\": \"tumor_largest_dimension_diameter\",\n", + " },\n", + " {\n", + " # mapper can be a custom Python function\n", + " \"source\": \"Tumor_Site\",\n", + " \"target\": \"tissue_or_organ_of_origin\",\n", + " \"mapper\": map_tumor_site,\n", + " },\n", + " {\n", + " # Lambda functions can also be used as mappers\n", + " \"source\": \"Age\",\n", + " \"target\": \"days_to_birth\",\n", + " \"mapper\": lambda age: -age * 365.25,\n", + " },\n", + " {\n", + " \"source\": \"Age\",\n", + " \"target\": \"age_at_diagnosis\",\n", + " \"mapper\": lambda age: float(\"nan\") if pd.isnull(age) else ceil(age*365.25),\n", + " },\n", + " {\n", + " # We can also use a data frame to specify value mappings using the `matches` attribute\n", + " \"source\": \"Histologic_type\",\n", + " \"target\": \"primary_diagnosis\",\n", + " \"matches\": hist_type_vmap\n", + " },\n", + " # For dataframes that contain the 'source' and 'target' columns as attributes,\n", + " # such as the ones returned by the match_values() function, we can directly\n", + " # use them as mappings\n", + " ethinicity_vmap,\n", + " race_vmap,\n", + "]\n", + "\n", + "\n", + "harmonization_spec = bdi.merge_mappings(value_mappings, user_mappings)\n" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Finally, we generate the harmonized dataset, with the user-defined value mappings." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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bmitumor_largest_dimension_diametertissue_or_organ_of_origindays_to_birthage_at_diagnosisprimary_diagnosisethnicityracecountry_of_birthhistory_of_tumor_typeirs_stagegendertumor_focalitytumor_shape
038.882.9Endometrium-23376.0023376.0Endometrioid carcinomanot hispanic or latinowhiteUnited StatesNoneNonefemaleUnifocalDome
139.763.5Endometrium-21184.5021185.0Endometrioid carcinomanot hispanic or latinowhiteUnited StatesNoneNonefemaleUnifocalDome
251.194.5Endometrium-18262.5018263.0Endometrioid carcinomanot hispanic or latinowhiteUnited StatesNoneNonefemaleUnifocalNone
3NaNNaNEndometriumNaNNaNCarcinosarcoma, NOSNaNNaNNaNPhenochromocytoma or ParagangliomaNoneNaNNaNNaN
432.693.5Endometrium-27393.7527394.0Endometrioid carcinomanot hispanic or latinowhiteUnited StatesNoneNonefemaleUnifocalNone
.............................................
9929.404.2Endometrium-27393.7527394.0Endometrioid carcinomaNaNNaNUkraineNoneNonefemaleUnifocalNone
10035.421.5Endometrium-27028.5027029.0Endometrioid carcinomaNaNNaNUkraineNoneNonefemaleUnifocalNone
10124.323.8Endometrium-31046.2531047.0Serous cystadenocarcinomanot hispanic or latinoblack or african americanUnited StatesNoneNonefemaleUnifocalNone
10234.065.0Endometrium-25567.5025568.0Serous cystadenocarcinomaNaNNaNUkraineNoneNonefemaleUnifocalNone
103NaNNaNEndometriumNaNNaNSerous cystadenocarcinomaNaNNaNUkraineNoneNoneNaNNaNNone
\n", + "

104 rows × 14 columns

\n", + "
" + ], + "text/plain": [ + " bmi tumor_largest_dimension_diameter tissue_or_organ_of_origin \\\n", + "0 38.88 2.9 Endometrium \n", + "1 39.76 3.5 Endometrium \n", + "2 51.19 4.5 Endometrium \n", + "3 NaN NaN Endometrium \n", + "4 32.69 3.5 Endometrium \n", + ".. ... ... ... \n", + "99 29.40 4.2 Endometrium \n", + "100 35.42 1.5 Endometrium \n", + "101 24.32 3.8 Endometrium \n", + "102 34.06 5.0 Endometrium \n", + "103 NaN NaN Endometrium \n", + "\n", + " days_to_birth age_at_diagnosis primary_diagnosis \\\n", + "0 -23376.00 23376.0 Endometrioid carcinoma \n", + "1 -21184.50 21185.0 Endometrioid carcinoma \n", + "2 -18262.50 18263.0 Endometrioid carcinoma \n", + "3 NaN NaN Carcinosarcoma, NOS \n", + "4 -27393.75 27394.0 Endometrioid carcinoma \n", + ".. ... ... ... \n", + "99 -27393.75 27394.0 Endometrioid carcinoma \n", + "100 -27028.50 27029.0 Endometrioid carcinoma \n", + "101 -31046.25 31047.0 Serous cystadenocarcinoma \n", + "102 -25567.50 25568.0 Serous cystadenocarcinoma \n", + "103 NaN NaN Serous cystadenocarcinoma \n", + "\n", + " ethnicity race country_of_birth \\\n", + "0 not hispanic or latino white United States \n", + "1 not hispanic or latino white United States \n", + "2 not hispanic or latino white United States \n", + "3 NaN NaN NaN \n", + "4 not hispanic or latino white United States \n", + ".. ... ... ... \n", + "99 NaN NaN Ukraine \n", + "100 NaN NaN Ukraine \n", + "101 not hispanic or latino black or african american United States \n", + "102 NaN NaN Ukraine \n", + "103 NaN NaN Ukraine \n", + "\n", + " history_of_tumor_type irs_stage gender tumor_focality \\\n", + "0 None None female Unifocal \n", + "1 None None female Unifocal \n", + "2 None None female Unifocal \n", + "3 Phenochromocytoma or Paraganglioma None NaN NaN \n", + "4 None None female Unifocal \n", + ".. ... ... ... ... \n", + "99 None None female Unifocal \n", + "100 None None female Unifocal \n", + "101 None None female Unifocal \n", + "102 None None female Unifocal \n", + "103 None None NaN NaN \n", + "\n", + " tumor_shape \n", + "0 Dome \n", + "1 Dome \n", + "2 None \n", + "3 NaN \n", + "4 None \n", + ".. ... \n", + "99 None \n", + "100 None \n", + "101 None \n", + "102 None \n", + "103 None \n", + "\n", + "[104 rows x 14 columns]" + ] + }, + "execution_count": 22, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "harmonized_dataset = bdi.materialize_mapping(dataset, harmonization_spec)\n", + "harmonized_dataset" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "For comparison, here is how our original data looked like:" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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BMITumor_Size_cmTumor_SiteAgeAgeHistologic_typeEthnicityRaceCountryHistologic_typeFIGO_stageGenderTumor_FocalityTumor_Site
038.882.9Anterior endometrium64.064.0EndometrioidNot-Hispanic or LatinoWhiteUnited StatesEndometrioidIAFemaleUnifocalAnterior endometrium
139.763.5Posterior endometrium58.058.0EndometrioidNot-Hispanic or LatinoWhiteUnited StatesEndometrioidIAFemaleUnifocalPosterior endometrium
251.194.5Other, specify50.050.0EndometrioidNot-Hispanic or LatinoWhiteUnited StatesEndometrioidIAFemaleUnifocalOther, specify
3NaNNaNNaNNaNNaNCarcinosarcomaNaNNaNNaNCarcinosarcomaNaNNaNNaNNaN
432.693.5Other, specify75.075.0EndometrioidNot-Hispanic or LatinoWhiteUnited StatesEndometrioidIAFemaleUnifocalOther, specify
.............................................
9929.404.2Other, specify75.075.0EndometrioidNaNNaNUkraineEndometrioidIAFemaleUnifocalOther, specify
10035.421.5Other, specify74.074.0EndometrioidNaNNaNUkraineEndometrioidIIFemaleUnifocalOther, specify
10124.323.8Other, specify85.085.0SerousNot-Hispanic or LatinoBlack or African AmericanUnited StatesSerousIIFemaleUnifocalOther, specify
10234.065.0Other, specify70.070.0SerousNaNNaNUkraineSerousIAFemaleUnifocalOther, specify
103NaNNaNNaNNaNNaNSerousNaNNaNUkraineSerousNaNNaNNaNNaN
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104 rows × 14 columns

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" + ], + "text/plain": [ + " BMI Tumor_Size_cm Tumor_Site Age Age Histologic_type \\\n", + "0 38.88 2.9 Anterior endometrium 64.0 64.0 Endometrioid \n", + "1 39.76 3.5 Posterior endometrium 58.0 58.0 Endometrioid \n", + "2 51.19 4.5 Other, specify 50.0 50.0 Endometrioid \n", + "3 NaN NaN NaN NaN NaN Carcinosarcoma \n", + "4 32.69 3.5 Other, specify 75.0 75.0 Endometrioid \n", + ".. ... ... ... ... ... ... \n", + "99 29.40 4.2 Other, specify 75.0 75.0 Endometrioid \n", + "100 35.42 1.5 Other, specify 74.0 74.0 Endometrioid \n", + "101 24.32 3.8 Other, specify 85.0 85.0 Serous \n", + "102 34.06 5.0 Other, specify 70.0 70.0 Serous \n", + "103 NaN NaN NaN NaN NaN Serous \n", + "\n", + " Ethnicity Race Country \\\n", + "0 Not-Hispanic or Latino White United States \n", + "1 Not-Hispanic or Latino White United States \n", + "2 Not-Hispanic or Latino White United States \n", + "3 NaN NaN NaN \n", + "4 Not-Hispanic or Latino White United States \n", + ".. ... ... ... \n", + "99 NaN NaN Ukraine \n", + "100 NaN NaN Ukraine \n", + "101 Not-Hispanic or Latino Black or African American United States \n", + "102 NaN NaN Ukraine \n", + "103 NaN NaN Ukraine \n", + "\n", + " Histologic_type FIGO_stage Gender Tumor_Focality Tumor_Site \n", + "0 Endometrioid IA Female Unifocal Anterior endometrium \n", + "1 Endometrioid IA Female Unifocal Posterior endometrium \n", + "2 Endometrioid IA Female Unifocal Other, specify \n", + "3 Carcinosarcoma NaN NaN NaN NaN \n", + "4 Endometrioid IA Female Unifocal Other, specify \n", + ".. ... ... ... ... ... \n", + "99 Endometrioid IA Female Unifocal Other, specify \n", + "100 Endometrioid II Female Unifocal Other, specify \n", + "101 Serous II Female Unifocal Other, specify \n", + "102 Serous IA Female Unifocal Other, specify \n", + "103 Serous NaN NaN NaN NaN \n", + "\n", + "[104 rows x 14 columns]" + ] + }, + "execution_count": 23, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "original_columns = map(lambda m: m[\"source\"], harmonization_spec)\n", + "dataset[original_columns]" + ] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.10.12" + } + }, + "nbformat": 4, + "nbformat_minor": 2 +} diff --git a/examples/getting-started-huang-gdc.ipynb b/examples/getting-started-huang-gdc.ipynb new file mode 100644 index 00000000..b03ae43a --- /dev/null +++ b/examples/getting-started-huang-gdc.ipynb @@ -0,0 +1,5224 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# Getting Started" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "First, import the `bdikit` library." + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [], + "source": [ + "import bdikit as bdi\n", + "import pandas as pd" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "In this example, we are mapping data from Dou et al. (https://pubmed.ncbi.nlm.nih.gov/37567170/) to the GDC format." + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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case_idagegendercountrysmoking_historysmoke_age_startsmoke_age_stopnum_smoke_per_daynum_pack_years_smsmoking_second_hand...tumor_pathology_reviewESTIMATE_stromal_scoreESTIMATE_immune_scoreCD3_IHC_countstemness_scoremutation_countneoAntigen_countchr_instability_idxintegrated_subtypetranscriptomic_subtype
0C3L-0097756MaleRussiaCurrent reformed smoker, years unknownNaNNaN20NaNYes...SCC 80%6825.9957557989.1159251.00.95324310602.003654BasalMesenchymal
1C3L-0098761MaleUkraineCurrent smoker: Includes daily and non-daily s...18NaN2043.0Yes...SCC 90%;SCC 90%;SCC 80%;SCC 70%5999.7934674772.4097160.00.8253308305.205612CINClassical
2C3L-0099450MaleUkraineCurrent reformed smoker within past 15 years1650610.2Exposure to secondhand smoke history not avail......SCC 40%;SCC 70%;SCC 40%;SCC 75%8924.0365648176.2339035.00.6645816701.684475ImmuneMesenchymal
3C3L-0099556MaleUkraineCurrent reformed smoker, more than 15 years25562031.0Exposure to secondhand smoke history not avail......SCC 90%;SCC 80%;SCC 40%;SCC 70%8723.4296678342.24634570.00.5399186401.340483ImmuneMesenchymal
4C3L-0099747MaleUkraineCurrent reformed smoker, more than 15 years12272015.0Yes...SCC 70%;SCC 70%7025.9116957445.25199160.00.84376512903.906370CINClassical
5C3L-0099956MaleRussiaCurrent smoker: Includes daily and non-daily s...20NaN2036.0Yes...SCC 80%;SCC 70%8510.7045518210.54955530.00.54897715901.148834ImmuneAtypical
6C3L-0113862MaleUkraineCurrent smoker: Includes daily and non-daily s...8NaN2054.0Exposure to secondhand smoke history not avail......SCC 70%6283.4238556407.89347810.00.89079018713.924982BasalClassical
7C3L-0123757MaleUkraineCurrent reformed smoker, more than 15 years1720406.0Exposure to secondhand smoke history not avail......SCC 80%7175.6677255720.28705530.00.73832814114.286490CINClassical
8C3L-0261764MaleBulgariaCurrent smoker: Includes daily and non-daily s...20NaN3066.0Yes...SCC 90%;SCC 80%;SCC 80%;SCC 80%;SCC 80%6346.8155846958.573390NaN0.90646647014.744818CINClassical
9C3L-0262168MaleBulgariaCurrent smoker: Includes daily and non-daily s...38NaN3045.0Yes...SCC 70%;SCC 70%;SCC 70%;SCC 70%;SCC 65%6806.3842648039.787184NaN0.75495035801.774521CINAtypical
\n", + "

10 rows × 37 columns

\n", + "
" + ], + "text/plain": [ + " case_id age gender country \\\n", + "0 C3L-00977 56 Male Russia \n", + "1 C3L-00987 61 Male Ukraine \n", + "2 C3L-00994 50 Male Ukraine \n", + "3 C3L-00995 56 Male Ukraine \n", + "4 C3L-00997 47 Male Ukraine \n", + "5 C3L-00999 56 Male Russia \n", + "6 C3L-01138 62 Male Ukraine \n", + "7 C3L-01237 57 Male Ukraine \n", + "8 C3L-02617 64 Male Bulgaria \n", + "9 C3L-02621 68 Male Bulgaria \n", + "\n", + " smoking_history smoke_age_start \\\n", + "0 Current reformed smoker, years unknown NaN \n", + "1 Current smoker: Includes daily and non-daily s... 18 \n", + "2 Current reformed smoker within past 15 years 16 \n", + "3 Current reformed smoker, more than 15 years 25 \n", + "4 Current reformed smoker, more than 15 years 12 \n", + "5 Current smoker: Includes daily and non-daily s... 20 \n", + "6 Current smoker: Includes daily and non-daily s... 8 \n", + "7 Current reformed smoker, more than 15 years 17 \n", + "8 Current smoker: Includes daily and non-daily s... 20 \n", + "9 Current smoker: Includes daily and non-daily s... 38 \n", + "\n", + " smoke_age_stop num_smoke_per_day num_pack_years_sm \\\n", + "0 NaN 20 NaN \n", + "1 NaN 20 43.0 \n", + "2 50 6 10.2 \n", + "3 56 20 31.0 \n", + "4 27 20 15.0 \n", + "5 NaN 20 36.0 \n", + "6 NaN 20 54.0 \n", + "7 20 40 6.0 \n", + "8 NaN 30 66.0 \n", + "9 NaN 30 45.0 \n", + "\n", + " smoking_second_hand ... \\\n", + "0 Yes ... \n", + "1 Yes ... \n", + "2 Exposure to secondhand smoke history not avail... ... \n", + "3 Exposure to secondhand smoke history not avail... ... \n", + "4 Yes ... \n", + "5 Yes ... \n", + "6 Exposure to secondhand smoke history not avail... ... \n", + "7 Exposure to secondhand smoke history not avail... ... \n", + "8 Yes ... \n", + "9 Yes ... \n", + "\n", + " tumor_pathology_review ESTIMATE_stromal_score \\\n", + "0 SCC 80% 6825.995755 \n", + "1 SCC 90%;SCC 90%;SCC 80%;SCC 70% 5999.793467 \n", + "2 SCC 40%;SCC 70%;SCC 40%;SCC 75% 8924.036564 \n", + "3 SCC 90%;SCC 80%;SCC 40%;SCC 70% 8723.429667 \n", + "4 SCC 70%;SCC 70% 7025.911695 \n", + "5 SCC 80%;SCC 70% 8510.704551 \n", + "6 SCC 70% 6283.423855 \n", + "7 SCC 80% 7175.667725 \n", + "8 SCC 90%;SCC 80%;SCC 80%;SCC 80%;SCC 80% 6346.815584 \n", + "9 SCC 70%;SCC 70%;SCC 70%;SCC 70%;SCC 65% 6806.384264 \n", + "\n", + " ESTIMATE_immune_score CD3_IHC_count stemness_score mutation_count \\\n", + "0 7989.115925 1.0 0.953243 106 \n", + "1 4772.409716 0.0 0.825330 83 \n", + "2 8176.233903 5.0 0.664581 67 \n", + "3 8342.246345 70.0 0.539918 64 \n", + "4 7445.251991 60.0 0.843765 129 \n", + "5 8210.549555 30.0 0.548977 159 \n", + "6 6407.893478 10.0 0.890790 187 \n", + "7 5720.287055 30.0 0.738328 141 \n", + "8 6958.573390 NaN 0.906466 470 \n", + "9 8039.787184 NaN 0.754950 358 \n", + "\n", + " neoAntigen_count chr_instability_idx integrated_subtype \\\n", + "0 0 2.003654 Basal \n", + "1 0 5.205612 CIN \n", + "2 0 1.684475 Immune \n", + "3 0 1.340483 Immune \n", + "4 0 3.906370 CIN \n", + "5 0 1.148834 Immune \n", + "6 1 3.924982 Basal \n", + "7 1 4.286490 CIN \n", + "8 1 4.744818 CIN \n", + "9 0 1.774521 CIN \n", + "\n", + " transcriptomic_subtype \n", + "0 Mesenchymal \n", + "1 Classical \n", + "2 Mesenchymal \n", + "3 Mesenchymal \n", + "4 Classical \n", + "5 Atypical \n", + "6 Classical \n", + "7 Classical \n", + "8 Classical \n", + "9 Atypical \n", + "\n", + "[10 rows x 37 columns]" + ] + }, + "execution_count": 3, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "dataset = pd.read_csv(\"./datasets/Huang.csv\")\n", + "\n", + "# columns = [\n", + "# \"Country\",\n", + "# \"Histologic_type\",\n", + "# \"FIGO_stage\",\n", + "# \"BMI\",\n", + "# \"Age\",\n", + "# \"Race\",\n", + "# \"Ethnicity\",\n", + "# \"Gender\",\n", + "# \"Tumor_Focality\",\n", + "# \"Tumor_Size_cm\",\n", + "# ]\n", + "\n", + "# dataset[columns].head(10)\n", + "dataset.head(10)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Matching the table schema to GDC standard vocabulary\n", + "\n", + "`bdi-kit` offers a suite of functions to help with data harmonization tasks.\n", + "For instance, it can help with automatic discovery of one-to-one mappings between the columns in the input (source) dataset and a target dataset schema. The target schema can be either another table or a standard data vocabulary such as the GDC (Genomic Data Commons).\n", + "\n", + "To achieve this using `bdi-kit`, we can use the `match_schema()` function to match columns to the GDC vocabulary schema as follows." + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Extracting features from 37 columns...\n" + ] + }, + { + "data": { + "application/vnd.jupyter.widget-view+json": { + "model_id": "ac73cc03d9f24fbba8dec5864b71faab", + "version_major": 2, + "version_minor": 0 + }, + "text/plain": [ + " 0%| | 0/37 [00:00\n", + "\n", + "\n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + "
sourcetarget
0case_idcatalog_reference
1ageage_at_onset
2gendergender
3countrycountry_of_birth
4smoking_historytobacco_smoking_status
5smoke_age_startyears_smoked
6smoke_age_stopyears_smoked
7num_smoke_per_dayyears_smoked
8num_pack_years_smpack_years_smoked
9smoking_second_handrelative_smoker
10smoking_inferredrelative_smoker
11alcohol_consumalcohol_intensity
12num_yrs_alc_conundescended_testis_corrected_age
13tumor_site_originalprimary_site
14tumor_site_curatedtumor_depth_descriptor
15tumor_focalitytumor_focality
16tumor_size_cmtumor_width_measurement
17histologic_typeroots
18histologic_gradewho_nte_grade
19tumor_necrosisnecrosis_present
20patho_staging_ptensat_pathologic_t
21patho_staging_pnajcc_pathologic_n
22clinic_staging_dist_metasuicc_clinical_m
23tumor_stageensat_pathologic_stage
24P16scan_tracer_used
25HPV_inferencevascular_invasion_present
26NAT_pathology_reviewstaining_intensity_scale
27tumor_pathology_reviewbest_overall_response
28ESTIMATE_stromal_scoretranscript
29ESTIMATE_immune_scoretranscript
30CD3_IHC_countcd4_count
31stemness_scoretranscript
32mutation_countmutation_codon
33neoAntigen_countensat_pathologic_n
34chr_instability_idxtranscript
35integrated_subtyperoots
36transcriptomic_subtypefab_morphology_code
\n", + "" + ], + "text/plain": [ + " source target\n", + "0 case_id catalog_reference\n", + "1 age age_at_onset\n", + "2 gender gender\n", + "3 country country_of_birth\n", + "4 smoking_history tobacco_smoking_status\n", + "5 smoke_age_start years_smoked\n", + "6 smoke_age_stop years_smoked\n", + "7 num_smoke_per_day years_smoked\n", + "8 num_pack_years_sm pack_years_smoked\n", + "9 smoking_second_hand relative_smoker\n", + "10 smoking_inferred relative_smoker\n", + "11 alcohol_consum alcohol_intensity\n", + "12 num_yrs_alc_con undescended_testis_corrected_age\n", + "13 tumor_site_original primary_site\n", + "14 tumor_site_curated tumor_depth_descriptor\n", + "15 tumor_focality tumor_focality\n", + "16 tumor_size_cm tumor_width_measurement\n", + "17 histologic_type roots\n", + "18 histologic_grade who_nte_grade\n", + "19 tumor_necrosis necrosis_present\n", + "20 patho_staging_pt ensat_pathologic_t\n", + "21 patho_staging_pn ajcc_pathologic_n\n", + "22 clinic_staging_dist_metas uicc_clinical_m\n", + "23 tumor_stage ensat_pathologic_stage\n", + "24 P16 scan_tracer_used\n", + "25 HPV_inference vascular_invasion_present\n", + "26 NAT_pathology_review staining_intensity_scale\n", + "27 tumor_pathology_review best_overall_response\n", + "28 ESTIMATE_stromal_score transcript\n", + "29 ESTIMATE_immune_score transcript\n", + "30 CD3_IHC_count cd4_count\n", + "31 stemness_score transcript\n", + "32 mutation_count mutation_codon\n", + "33 neoAntigen_count ensat_pathologic_n\n", + "34 chr_instability_idx transcript\n", + "35 integrated_subtype roots\n", + "36 transcriptomic_subtype fab_morphology_code" + ] + }, + "execution_count": 6, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "column_mappings = bdi.match_schema(dataset, target=\"gdc\", method=\"ct_learning\")\n", + "column_mappings" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Generating a harmonized table\n", + "\n", + "After discovering a schema mapping, we can generate a new table (DataFrame) using the new column names from the GDC standard vocabulary.\n", + "\n", + "To do so using `bdi-kit`, we can use the function `materialize_mapping()` as follows. Note that the column headers have been renamed to the target schema." + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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country_of_birthdysplasia_typefigo_stagehpv_positive_typeweightraceethnicitygendertumor_focalitytumor_depth
0United StatesEndometrioidIA38.8864.0WhiteNot-Hispanic or LatinoFemaleUnifocal2.9
1United StatesEndometrioidIA39.7658.0WhiteNot-Hispanic or LatinoFemaleUnifocal3.5
2United StatesEndometrioidIA51.1950.0WhiteNot-Hispanic or LatinoFemaleUnifocal4.5
3NaNCarcinosarcomaNaNNaNNaNNaNNaNNaNNaNNaN
4United StatesEndometrioidIA32.6975.0WhiteNot-Hispanic or LatinoFemaleUnifocal3.5
.................................
99UkraineEndometrioidIA29.4075.0NaNNaNFemaleUnifocal4.2
100UkraineEndometrioidII35.4274.0NaNNaNFemaleUnifocal1.5
101United StatesSerousII24.3285.0Black or African AmericanNot-Hispanic or LatinoFemaleUnifocal3.8
102UkraineSerousIA34.0670.0NaNNaNFemaleUnifocal5.0
103UkraineSerousNaNNaNNaNNaNNaNNaNNaNNaN
\n", + "

104 rows × 10 columns

\n", + "
" + ], + "text/plain": [ + " country_of_birth dysplasia_type figo_stage hpv_positive_type weight \\\n", + "0 United States Endometrioid IA 38.88 64.0 \n", + "1 United States Endometrioid IA 39.76 58.0 \n", + "2 United States Endometrioid IA 51.19 50.0 \n", + "3 NaN Carcinosarcoma NaN NaN NaN \n", + "4 United States Endometrioid IA 32.69 75.0 \n", + ".. ... ... ... ... ... \n", + "99 Ukraine Endometrioid IA 29.40 75.0 \n", + "100 Ukraine Endometrioid II 35.42 74.0 \n", + "101 United States Serous II 24.32 85.0 \n", + "102 Ukraine Serous IA 34.06 70.0 \n", + "103 Ukraine Serous NaN NaN NaN \n", + "\n", + " race ethnicity gender tumor_focality \\\n", + "0 White Not-Hispanic or Latino Female Unifocal \n", + "1 White Not-Hispanic or Latino Female Unifocal \n", + "2 White Not-Hispanic or Latino Female Unifocal \n", + "3 NaN NaN NaN NaN \n", + "4 White Not-Hispanic or Latino Female Unifocal \n", + ".. ... ... ... ... \n", + "99 NaN NaN Female Unifocal \n", + "100 NaN NaN Female Unifocal \n", + "101 Black or African American Not-Hispanic or Latino Female Unifocal \n", + "102 NaN NaN Female Unifocal \n", + "103 NaN NaN NaN NaN \n", + "\n", + " tumor_depth \n", + "0 2.9 \n", + "1 3.5 \n", + "2 4.5 \n", + "3 NaN \n", + "4 3.5 \n", + ".. ... \n", + "99 4.2 \n", + "100 1.5 \n", + "101 3.8 \n", + "102 5.0 \n", + "103 NaN \n", + "\n", + "[104 rows x 10 columns]" + ] + }, + "execution_count": 4, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.materialize_mapping(dataset, column_mappings)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Generating a harmonized table with value mappings\n", + "\n", + "`bdi-kit` can also help with translation of the values from the source table to the target standard format.\n", + "\n", + "To this end, `bdi-kit` provides the function `match_values()` that automatically creates value mappings for each string column.\n", + "The output of `match_values()` can be fed to `materialize_mapping()` which materialized the final target using both schema and value mappings." + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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country_of_birthdysplasia_typefigo_stageraceethnicitygendertumor_focality
0United StatesNoneStage IAwhitenot hispanic or latinofemaleUnifocal
1United StatesNoneStage IAwhitenot hispanic or latinofemaleUnifocal
2United StatesNoneStage IAwhitenot hispanic or latinofemaleUnifocal
3NaNEsophageal Mucosa Columnar DysplasiaNaNNaNNaNNaNNaN
4United StatesNoneStage IAwhitenot hispanic or latinofemaleUnifocal
........................
99UkraineNoneStage IANaNNaNfemaleUnifocal
100UkraineNoneStage IIINaNNaNfemaleUnifocal
101United StatesNoneStage IIIblack or african americannot hispanic or latinofemaleUnifocal
102UkraineNoneStage IANaNNaNfemaleUnifocal
103UkraineNoneNaNNaNNaNNaNNaN
\n", + "

104 rows × 7 columns

\n", + "
" + ], + "text/plain": [ + " country_of_birth dysplasia_type figo_stage \\\n", + "0 United States None Stage IA \n", + "1 United States None Stage IA \n", + "2 United States None Stage IA \n", + "3 NaN Esophageal Mucosa Columnar Dysplasia NaN \n", + "4 United States None Stage IA \n", + ".. ... ... ... \n", + "99 Ukraine None Stage IA \n", + "100 Ukraine None Stage III \n", + "101 United States None Stage III \n", + "102 Ukraine None Stage IA \n", + "103 Ukraine None NaN \n", + "\n", + " race ethnicity gender tumor_focality \n", + "0 white not hispanic or latino female Unifocal \n", + "1 white not hispanic or latino female Unifocal \n", + "2 white not hispanic or latino female Unifocal \n", + "3 NaN NaN NaN NaN \n", + "4 white not hispanic or latino female Unifocal \n", + ".. ... ... ... ... \n", + "99 NaN NaN female Unifocal \n", + "100 NaN NaN female Unifocal \n", + "101 black or african american not hispanic or latino female Unifocal \n", + "102 NaN NaN female Unifocal \n", + "103 NaN NaN NaN NaN \n", + "\n", + "[104 rows x 7 columns]" + ] + }, + "execution_count": 5, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "value_mappings = bdi.match_values(dataset, column_mapping=column_mappings, target=\"gdc\", method=\"tfidf\")\n", + "bdi.materialize_mapping(dataset, value_mappings)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Verifying the schema mappings\n", + "\n", + "Sometimes the mappings generated automatically may be incorrect or you may to want verify them individually.\n", + "To verify the suggested column mappings, `bdi-kit` offers additional APIs to visualize the data and make any modifications when necessary. \n", + "\n", + "For this example, we will use the column `Histologic_type`. We can start by exploring the columns most similar to `Histologic_type`. \n", + "\n", + "For this, we can use the `top_matches()` function. Here, we notice that `primary_diagnosis` could be a potential target column.\n" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": {}, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "Some weights of RobertaModel were not initialized from the model checkpoint at roberta-base and are newly initialized: ['roberta.pooler.dense.bias', 'roberta.pooler.dense.weight']\n", + "You should probably TRAIN this model on a down-stream task to be able to use it for predictions and inference.\n", + "100%|██████████| 1/1 [00:00<00:00, 14.70it/s]\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Table features extracted from 1 columns\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "100%|██████████| 734/734 [00:58<00:00, 12.48it/s]" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Table features extracted from 734 columns\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "\n" + ] + }, + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Histologic_typedescribed_cases0.589956
1Histologic_typeslide_images0.587552
2Histologic_typehistory_of_tumor_type0.574640
3Histologic_typeprimary_diagnosis0.573583
4Histologic_typeadditional_pathology_findings0.562278
5Histologic_typepathology_details0.562007
6Histologic_typepathology_reports0.547307
7Histologic_typerelationship_primary_diagnosis0.524285
8Histologic_typediagnoses0.519854
9Histologic_typefamily_histories0.516649
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Histologic_type described_cases 0.589956\n", + "1 Histologic_type slide_images 0.587552\n", + "2 Histologic_type history_of_tumor_type 0.574640\n", + "3 Histologic_type primary_diagnosis 0.573583\n", + "4 Histologic_type additional_pathology_findings 0.562278\n", + "5 Histologic_type pathology_details 0.562007\n", + "6 Histologic_type pathology_reports 0.547307\n", + "7 Histologic_type relationship_primary_diagnosis 0.524285\n", + "8 Histologic_type diagnoses 0.519854\n", + "9 Histologic_type family_histories 0.516649" + ] + }, + "execution_count": 6, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "hist_type_matches = bdi.top_matches(dataset, columns=[\"Histologic_type\"], target=\"gdc\")\n", + "hist_type_matches" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Viewing the column domains\n", + "\n", + "To verify that `primary_diagnosis` is a good target column, we view and compare the domains of each column using the `preview_domain()` function. For the source table, it returns the list of unique values in the source column. For the GDC target, it returns the list of unique valid values that a column can have.\n", + "\n", + "Here we see that the values seem to be related." + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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value_name
0Endometrioid
1Carcinosarcoma
2Serous
3Clear cell
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" + ], + "text/plain": [ + " value_name\n", + "0 Endometrioid\n", + "1 Carcinosarcoma\n", + "2 Serous\n", + "3 Clear cell" + ] + }, + "execution_count": 7, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.preview_domain(dataset, \"Histologic_type\")" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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value_namevalue_descriptioncolumn_description
0Abdominal desmoidAn insidious poorly circumscribed neoplasm ari...Text term used to describe the patient's histo...
1Abdominal fibromatosisAn insidious poorly circumscribed neoplasm ari...
2Achromic nevusA benign nevus characterized by the absence of...
3Acidophil adenocarcinomaA malignant epithelial neoplasm of the anterio...
4Acidophil adenomaAn epithelial neoplasm of the anterior pituita...
............
2620Wolffian duct tumorAn epithelial neoplasm of the female reproduct...
2621XanthofibromaA benign neoplasm composed of fibroblastic spi...
2622Yolk sac tumorA non-seminomatous malignant germ cell tumor c...
2623UnknownNot known, not observed, not recorded, or refu...
2624Not ReportedNot provided or available.
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2625 rows × 3 columns

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" + ], + "text/plain": [ + " value_name \\\n", + "0 Abdominal desmoid \n", + "1 Abdominal fibromatosis \n", + "2 Achromic nevus \n", + "3 Acidophil adenocarcinoma \n", + "4 Acidophil adenoma \n", + "... ... \n", + "2620 Wolffian duct tumor \n", + "2621 Xanthofibroma \n", + "2622 Yolk sac tumor \n", + "2623 Unknown \n", + "2624 Not Reported \n", + "\n", + " value_description \\\n", + "0 An insidious poorly circumscribed neoplasm ari... \n", + "1 An insidious poorly circumscribed neoplasm ari... \n", + "2 A benign nevus characterized by the absence of... \n", + "3 A malignant epithelial neoplasm of the anterio... \n", + "4 An epithelial neoplasm of the anterior pituita... \n", + "... ... \n", + "2620 An epithelial neoplasm of the female reproduct... \n", + "2621 A benign neoplasm composed of fibroblastic spi... \n", + "2622 A non-seminomatous malignant germ cell tumor c... \n", + "2623 Not known, not observed, not recorded, or refu... \n", + "2624 Not provided or available. \n", + "\n", + " column_description \n", + "0 Text term used to describe the patient's histo... \n", + "1 \n", + "2 \n", + "3 \n", + "4 \n", + "... ... \n", + "2620 \n", + "2621 \n", + "2622 \n", + "2623 \n", + "2624 \n", + "\n", + "[2625 rows x 3 columns]" + ] + }, + "execution_count": 8, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.preview_domain(\"gdc\", \"primary_diagnosis\")" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Since `primary_diagnosis` looks like a correct match for `Histologic_type`, we can modify the `column_mappings` variable directly." + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetarget
0Countrycountry_of_birth
1Histologic_typeprimary_diagnosis
2FIGO_stagefigo_stage
3BMIhpv_positive_type
4Ageweight
5Racerace
6Ethnicityethnicity
7Gendergender
8Tumor_Focalitytumor_focality
9Tumor_Size_cmtumor_depth
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" + ], + "text/plain": [ + " source target\n", + "0 Country country_of_birth\n", + "1 Histologic_type primary_diagnosis\n", + "2 FIGO_stage figo_stage\n", + "3 BMI hpv_positive_type\n", + "4 Age weight\n", + "5 Race race\n", + "6 Ethnicity ethnicity\n", + "7 Gender gender\n", + "8 Tumor_Focality tumor_focality\n", + "9 Tumor_Size_cm tumor_depth" + ] + }, + "execution_count": 8, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "column_mappings.loc[column_mappings[\"source\"] == \"Histologic_type\", \"target\"] = \"primary_diagnosis\"\n", + "column_mappings" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Finding correct value mappings\n", + "\n", + "After finding the correct column, we need to find appropriate value mappings. \n", + "Using `match_values()`, we can inspect what the possible value mappings for this would look like after the harmonization.\n", + "\n", + "`bdi-kit` implements multiple methods for value mapping discovery, including:\n", + "\n", + " - `edit_distance` - Computes value similarities using Levenstein's edit distance measure.\n", + " - `tfidf` - A method based on tf-idf importance weighting computed over charcter n-grams.\n", + " - `embeddings` - Uses BERT word embeddings to compute \"semantic similarity\" between the values.\n", + "\n", + "To specify a value mapping approach, we can pass the `method` parameter." + ] + }, + { + "cell_type": "code", + "execution_count": 9, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0CarcinosarcomaCarcinosarcoma, NOS0.848485
1Clear cellClear cell adenoma0.714286
2EndometrioidStromal endometriosis0.666667
3SerousNeuronevus0.625000
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Carcinosarcoma Carcinosarcoma, NOS 0.848485\n", + "1 Clear cell Clear cell adenoma 0.714286\n", + "2 Endometrioid Stromal endometriosis 0.666667\n", + "3 Serous Neuronevus 0.625000" + ] + }, + "execution_count": 9, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.match_values(\n", + " dataset, column_mapping=(\"Histologic_type\", \"primary_diagnosis\"), target=\"gdc\", method=\"edit_distance\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": 10, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0CarcinosarcomaCarcinosarcoma, NOS0.969
1EndometrioidEndometrioid adenoma, NOS0.897
2Clear cellClear cell adenoma0.853
3SerousSerous carcinoma, NOS0.755
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Carcinosarcoma Carcinosarcoma, NOS 0.969\n", + "1 Endometrioid Endometrioid adenoma, NOS 0.897\n", + "2 Clear cell Clear cell adenoma 0.853\n", + "3 Serous Serous carcinoma, NOS 0.755" + ] + }, + "execution_count": 10, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.match_values(\n", + " dataset, column_mapping=(\"Histologic_type\", \"primary_diagnosis\"), target=\"gdc\", method=\"tfidf\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": 11, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0CarcinosarcomaCarcinofibroma0.919
1EndometrioidEndometrioid cystadenocarcinoma0.810
2Clear cellClear cell carcinoma0.760
3SerousSerous cystoma0.661
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Carcinosarcoma Carcinofibroma 0.919\n", + "1 Endometrioid Endometrioid cystadenocarcinoma 0.810\n", + "2 Clear cell Clear cell carcinoma 0.760\n", + "3 Serous Serous cystoma 0.661" + ] + }, + "execution_count": 11, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.match_values(\n", + " dataset, column_mapping=(\"Histologic_type\", \"primary_diagnosis\"), target=\"gdc\", method=\"embedding\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": 12, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetarget
0CarcinosarcomaCarcinosarcoma, NOS
1Clear cellClear cell adenocarcinoma, NOS
2EndometrioidEndometrioid carcinoma
3SerousSerous cystadenocarcinoma
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" + ], + "text/plain": [ + " source target\n", + "0 Carcinosarcoma Carcinosarcoma, NOS\n", + "1 Clear cell Clear cell adenocarcinoma, NOS\n", + "2 Endometrioid Endometrioid carcinoma\n", + "3 Serous Serous cystadenocarcinoma" + ] + }, + "execution_count": 12, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "hist_type_vmap = pd.DataFrame(\n", + " columns=[\"source\", \"target\"],\n", + " data=[\n", + " (\"Carcinosarcoma\", \"Carcinosarcoma, NOS\"),\n", + " (\"Clear cell\", \"Clear cell adenocarcinoma, NOS\"),\n", + " (\"Endometrioid\", \"Endometrioid carcinoma\"),\n", + " (\"Serous\", \"Serous cystadenocarcinoma\"),\n", + " ],\n", + ")\n", + "hist_type_vmap" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Verifying multiple value mappings at once\n", + "\n", + "Besides verifying value mappings individually, you can also do it for all column mappings at once." + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "gender => gender\n" + ] + }, + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Malemale1.0
1Femalefemale1.0
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Male male 1.0\n", + "1 Female female 1.0" + ] + }, + "metadata": {}, + "output_type": "display_data" + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "\n", + "country => country_of_birth\n" + ] + }, + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0RussiaRussia1.0
1UkraineUkraine1.0
2BulgariaBulgaria1.0
3PolandPoland1.0
4United StatesUnited States1.0
5ChinaChina1.0
6ArmeniaArmenia1.0
7TSS did not collectNoneNaN
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sourcetargetsimilarity
0Current reformed smoker, more than 15 yearsCurrent Reformed Smoker for > 15 yrs0.823
1Current reformed smoker, years unknownCurrent Reformed Smoker for > 15 yrs0.756
2Current reformed smoker within past 15 yearsCurrent Reformed Smoker for > 15 yrs0.719
3Lifelong non-smoker: Less than 100 cigarettes ...Lifelong Non-Smoker0.697
4Smoking history not availableSmoking history not documented0.564
5Current smoker: Includes daily and non-daily s...Current Smoker0.506
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5Normal 25%%NoneNone
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7Normal 20%%NoneNone
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13Normal EPI 10%;Normal EPI 10%%NoneNone
14Normal 70$ EPI%NoneNone
15Normal Thyroid;Normal Thyroid;Normal No EPI%NoneNone
16Normal 40%%NoneNone
17Normal 5%%NoneNone
18Normal 1%%NoneNone
19Normal 20%;SCC 75%%NoneNone
20SCC 30%;SCC 20%%NoneNone
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25N 15%%NoneNone
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27Normal 20%;Normal No EPI;Normal 5%%NoneNone
28N 0%%NoneNone
29N 20%%NoneNone
30Normal 20% EPI%NoneNone
31Normal 15%;Normal 5%%NoneNone
32Normal 30%%NoneNone
33Normal 10%%NoneNone
34Hyperplasia 70%%NoneNone
35N lymphoid B%NoneNone
36Normal no EPI%NoneNone
37SCC 75%%NoneNone
38Normal 10%;Normal 15%;SCC 90%%NoneNone
39Normal 0%%NoneNone
40N 10%%NoneNone
41Normal 15%%NoneNone
42N 30%%NoneNone
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Classical Not Classified 0.53\n", + "1 Mesenchymal None NaN\n", + "2 Atypical None NaN\n", + "3 Basal None NaN" + ] + }, + "metadata": {}, + "output_type": "display_data" + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "\n" + ] + } + ], + "source": [ + "mappings = bdi.match_values(\n", + " dataset,\n", + " column_mapping=column_mappings,\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + ")\n", + "\n", + "for mapping in mappings:\n", + " print(f\"{mapping.attrs['source']} => {mapping.attrs['target']}\")\n", + " display(mapping)\n", + " print(\"\")" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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value_namevalue_descriptioncolumn_description
0G1A morphologic qualifier indicating that a canc...The WHO (World Health Organization) grading cl...
1G2A morphologic qualifier indicating that a canc...
2G3A morphologic qualifier indicating that a canc...
3GXA morphologic qualifier indicating that the gr...
4Unknown
5Not ReportedNot provided or available.
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" + ], + "text/plain": [ + " value_name value_description \\\n", + "0 G1 A morphologic qualifier indicating that a canc... \n", + "1 G2 A morphologic qualifier indicating that a canc... \n", + "2 G3 A morphologic qualifier indicating that a canc... \n", + "3 GX A morphologic qualifier indicating that the gr... \n", + "4 Unknown \n", + "5 Not Reported Not provided or available. \n", + "\n", + " column_description \n", + "0 The WHO (World Health Organization) grading cl... \n", + "1 \n", + "2 \n", + "3 \n", + "4 \n", + "5 " + ] + }, + "execution_count": 8, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.preview_domain(\"gdc\", \"who_nte_grade\")" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Fixing remaining value mappings\n", + "\n", + "We need fix a few value mappings:\n", + "- Race\n", + "- Ethnicity\n", + "- Tumor_Site\n", + "\n", + "For race, we need to fix: `nan` -> `american indian or alaska native`." + ] + }, + { + "cell_type": "code", + "execution_count": 14, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Whitewhite1.000
1Asianasian1.000
2Not Reportednot reported1.000
3Black or African Americanblack or african american1.000
4nanamerican indian or alaska native0.359
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" + ], + "text/plain": [ + " source target similarity\n", + "0 White white 1.000\n", + "1 Asian asian 1.000\n", + "2 Not Reported not reported 1.000\n", + "3 Black or African American black or african american 1.000\n", + "4 nan american indian or alaska native 0.359" + ] + }, + "execution_count": 14, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "race_vmap = bdi.match_values(\n", + " dataset,\n", + " column_mapping=(\"Race\", \"race\"),\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + ")\n", + "race_vmap" + ] + }, + { + "cell_type": "code", + "execution_count": 15, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Whitewhite1.0
1Asianasian1.0
2Not Reportednot reported1.0
3Black or African Americanblack or african american1.0
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" + ], + "text/plain": [ + " source target similarity\n", + "0 White white 1.0\n", + "1 Asian asian 1.0\n", + "2 Not Reported not reported 1.0\n", + "3 Black or African American black or african american 1.0" + ] + }, + "execution_count": 15, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "race_vmap = race_vmap[race_vmap[\"similarity\"] >= 1.0]\n", + "race_vmap" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "For `Ethnicity`, we need to fix: `Not reported` -> `not hispanic or latino`." + ] + }, + { + "cell_type": "code", + "execution_count": 16, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Hispanic or Latinohispanic or latino1.000
1Not-Hispanic or Latinonot hispanic or latino0.935
2Not reportednot hispanic or latino0.268
3nanNoneNaN
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" + ], + "text/plain": [ + " source target similarity\n", + "0 Hispanic or Latino hispanic or latino 1.000\n", + "1 Not-Hispanic or Latino not hispanic or latino 0.935\n", + "2 Not reported not hispanic or latino 0.268\n", + "3 nan None NaN" + ] + }, + "execution_count": 16, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "ethinicity_vmap = bdi.match_values(\n", + " dataset,\n", + " column_mapping=(\"Ethnicity\", \"ethnicity\"),\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + ")\n", + "ethinicity_vmap\n" + ] + }, + { + "cell_type": "code", + "execution_count": 17, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Hispanic or Latinohispanic or latino1.000
1Not-Hispanic or Latinonot hispanic or latino0.935
\n", + "
" + ], + "text/plain": [ + " source target similarity\n", + "0 Hispanic or Latino hispanic or latino 1.000\n", + "1 Not-Hispanic or Latino not hispanic or latino 0.935" + ] + }, + "execution_count": 17, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "ethinicity_vmap = ethinicity_vmap[ethinicity_vmap[\"similarity\"] > 0.9]\n", + "ethinicity_vmap" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "For `Tumor_Site`, given that this dataset is about endometrial cancer, all values must be mapped to \"Endometrium\". So instead of fixing each mapping individually, we will write a custom function that returns \"Endometrium\" regardless of the input value. Later, we will show how to use this function to transform the dataset." + ] + }, + { + "cell_type": "code", + "execution_count": 18, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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sourcetargetsimilarity
0Anterior endometriumEndometrium0.852
1Posterior endometriumEndometrium0.823
2Other, specifyOther specified parts of pancreas0.543
3nanAnal canal0.301
\n", + "
" + ], + "text/plain": [ + " source target similarity\n", + "0 Anterior endometrium Endometrium 0.852\n", + "1 Posterior endometrium Endometrium 0.823\n", + "2 Other, specify Other specified parts of pancreas 0.543\n", + "3 nan Anal canal 0.301" + ] + }, + "execution_count": 18, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.match_values(\n", + " dataset, column_mapping=(\"Tumor_Site\", \"tissue_or_organ_of_origin\"), target=\"gdc\", method=\"tfidf\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": 19, + "metadata": {}, + "outputs": [], + "source": [ + "# Custom mapping function that will be used to map the values of the 'Tumor_Site' column\n", + "def map_tumor_site(source_value):\n", + " return \"Endometrium\"" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Combining custom user mappings with suggested mappings\n", + "\n", + "Before generating a final harmonized dataset, we can combine the automatically generated value mappings with the fixed mappings provided by the user. To do so, we use `bdi.merge_mappings()` function, which take a list of mappings (e.g., generated automatically) and a list of \"user-defined mapping overrides\" that will be combined with the first list of mappings and will take precedence whenever they conflict.\n", + "\n", + "In our example below, all mappings specified in the variable `user_mappings` will override the mappings in `value_mappings` generated by the `bdi.match_values()` function." + ] + }, + { + "cell_type": "code", + "execution_count": 20, + "metadata": {}, + "outputs": [], + "source": [ + "from math import ceil\n", + "\n", + "user_mappings = [\n", + " {\n", + " # When no mapping is need, specifying the source and target is enough\n", + " \"source\": \"BMI\",\n", + " \"target\": \"bmi\",\n", + " },\n", + " {\n", + " \"source\": \"Tumor_Size_cm\",\n", + " \"target\": \"tumor_largest_dimension_diameter\",\n", + " },\n", + " {\n", + " # mapper can be a custom Python function\n", + " \"source\": \"Tumor_Site\",\n", + " \"target\": \"tissue_or_organ_of_origin\",\n", + " \"mapper\": map_tumor_site,\n", + " },\n", + " {\n", + " # Lambda functions can also be used as mappers\n", + " \"source\": \"Age\",\n", + " \"target\": \"days_to_birth\",\n", + " \"mapper\": lambda age: -age * 365.25,\n", + " },\n", + " {\n", + " \"source\": \"Age\",\n", + " \"target\": \"age_at_diagnosis\",\n", + " \"mapper\": lambda age: float(\"nan\") if pd.isnull(age) else ceil(age*365.25),\n", + " },\n", + " {\n", + " # We can also use a data frame to specify value mappings using the `matches` attribute\n", + " \"source\": \"Histologic_type\",\n", + " \"target\": \"primary_diagnosis\",\n", + " \"matches\": hist_type_vmap\n", + " },\n", + " # For dataframes that contain the 'source' and 'target' columns as attributes,\n", + " # such as the ones returned by the match_values() function, we can directly\n", + " # use them as mappings\n", + " ethinicity_vmap,\n", + " race_vmap,\n", + "]\n", + "\n", + "\n", + "harmonization_spec = bdi.merge_mappings(value_mappings, user_mappings)\n" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Finally, we generate the harmonized dataset, with the user-defined value mappings." + ] + }, + { + "cell_type": "code", + "execution_count": 21, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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tissue_or_organ_of_originbmidays_to_birthage_at_diagnosistumor_largest_dimension_diametercountry_of_birthprimary_diagnosisfigo_stageraceethnicitygendertumor_focality
0Endometrium38.88-23376.0023376.02.9United StatesEndometrioid adenoma, NOSStage IAwhitenot hispanic or latinofemaleUnifocal
1Endometrium39.76-21184.5021185.03.5United StatesEndometrioid adenoma, NOSStage IAwhitenot hispanic or latinofemaleUnifocal
2Endometrium51.19-18262.5018263.04.5United StatesEndometrioid adenoma, NOSStage IAwhitenot hispanic or latinofemaleUnifocal
3EndometriumNaNNaNNaNNaNNaNCarcinosarcoma, NOSNaNNaNNaNNaNNaN
4Endometrium32.69-27393.7527394.03.5United StatesEndometrioid adenoma, NOSStage IAwhitenot hispanic or latinofemaleUnifocal
.......................................
99Endometrium29.40-27393.7527394.04.2UkraineEndometrioid adenoma, NOSStage IANaNNaNfemaleUnifocal
100Endometrium35.42-27028.5027029.01.5UkraineEndometrioid adenoma, NOSStage IIINaNNaNfemaleUnifocal
101Endometrium24.32-31046.2531047.03.8United StatesSerous carcinoma, NOSStage IIIblack or african americannot hispanic or latinofemaleUnifocal
102Endometrium34.06-25567.5025568.05.0UkraineSerous carcinoma, NOSStage IANaNNaNfemaleUnifocal
103EndometriumNaNNaNNaNNaNUkraineSerous carcinoma, NOSNaNNaNNaNNaNNaN
\n", + "

104 rows × 12 columns

\n", + "
" + ], + "text/plain": [ + " tissue_or_organ_of_origin bmi days_to_birth age_at_diagnosis \\\n", + "0 Endometrium 38.88 -23376.00 23376.0 \n", + "1 Endometrium 39.76 -21184.50 21185.0 \n", + "2 Endometrium 51.19 -18262.50 18263.0 \n", + "3 Endometrium NaN NaN NaN \n", + "4 Endometrium 32.69 -27393.75 27394.0 \n", + ".. ... ... ... ... \n", + "99 Endometrium 29.40 -27393.75 27394.0 \n", + "100 Endometrium 35.42 -27028.50 27029.0 \n", + "101 Endometrium 24.32 -31046.25 31047.0 \n", + "102 Endometrium 34.06 -25567.50 25568.0 \n", + "103 Endometrium NaN NaN NaN \n", + "\n", + " tumor_largest_dimension_diameter country_of_birth \\\n", + "0 2.9 United States \n", + "1 3.5 United States \n", + "2 4.5 United States \n", + "3 NaN NaN \n", + "4 3.5 United States \n", + ".. ... ... \n", + "99 4.2 Ukraine \n", + "100 1.5 Ukraine \n", + "101 3.8 United States \n", + "102 5.0 Ukraine \n", + "103 NaN Ukraine \n", + "\n", + " primary_diagnosis figo_stage race \\\n", + "0 Endometrioid adenoma, NOS Stage IA white \n", + "1 Endometrioid adenoma, NOS Stage IA white \n", + "2 Endometrioid adenoma, NOS Stage IA white \n", + "3 Carcinosarcoma, NOS NaN NaN \n", + "4 Endometrioid adenoma, NOS Stage IA white \n", + ".. ... ... ... \n", + "99 Endometrioid adenoma, NOS Stage IA NaN \n", + "100 Endometrioid adenoma, NOS Stage III NaN \n", + "101 Serous carcinoma, NOS Stage III black or african american \n", + "102 Serous carcinoma, NOS Stage IA NaN \n", + "103 Serous carcinoma, NOS NaN NaN \n", + "\n", + " ethnicity gender tumor_focality \n", + "0 not hispanic or latino female Unifocal \n", + "1 not hispanic or latino female Unifocal \n", + "2 not hispanic or latino female Unifocal \n", + "3 NaN NaN NaN \n", + "4 not hispanic or latino female Unifocal \n", + ".. ... ... ... \n", + "99 NaN female Unifocal \n", + "100 NaN female Unifocal \n", + "101 not hispanic or latino female Unifocal \n", + "102 NaN female Unifocal \n", + "103 NaN NaN NaN \n", + "\n", + "[104 rows x 12 columns]" + ] + }, + "execution_count": 21, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "harmonized_dataset = bdi.materialize_mapping(dataset, harmonization_spec)\n", + "harmonized_dataset" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "For comparison, here is how our original data looked like:" + ] + }, + { + "cell_type": "code", + "execution_count": 22, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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Tumor_SiteBMIAgeAgeTumor_Size_cmCountryHistologic_typeFIGO_stageRaceEthnicityGenderTumor_Focality
0Anterior endometrium38.8864.064.02.9United StatesEndometrioidIAWhiteNot-Hispanic or LatinoFemaleUnifocal
1Posterior endometrium39.7658.058.03.5United StatesEndometrioidIAWhiteNot-Hispanic or LatinoFemaleUnifocal
2Other, specify51.1950.050.04.5United StatesEndometrioidIAWhiteNot-Hispanic or LatinoFemaleUnifocal
3NaNNaNNaNNaNNaNNaNCarcinosarcomaNaNNaNNaNNaNNaN
4Other, specify32.6975.075.03.5United StatesEndometrioidIAWhiteNot-Hispanic or LatinoFemaleUnifocal
.......................................
99Other, specify29.4075.075.04.2UkraineEndometrioidIANaNNaNFemaleUnifocal
100Other, specify35.4274.074.01.5UkraineEndometrioidIINaNNaNFemaleUnifocal
101Other, specify24.3285.085.03.8United StatesSerousIIBlack or African AmericanNot-Hispanic or LatinoFemaleUnifocal
102Other, specify34.0670.070.05.0UkraineSerousIANaNNaNFemaleUnifocal
103NaNNaNNaNNaNNaNUkraineSerousNaNNaNNaNNaNNaN
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" + ], + "text/plain": [ + " Tumor_Site BMI Age Age Tumor_Size_cm Country \\\n", + "0 Anterior endometrium 38.88 64.0 64.0 2.9 United States \n", + "1 Posterior endometrium 39.76 58.0 58.0 3.5 United States \n", + "2 Other, specify 51.19 50.0 50.0 4.5 United States \n", + "3 NaN NaN NaN NaN NaN NaN \n", + "4 Other, specify 32.69 75.0 75.0 3.5 United States \n", + ".. ... ... ... ... ... ... \n", + "99 Other, specify 29.40 75.0 75.0 4.2 Ukraine \n", + "100 Other, specify 35.42 74.0 74.0 1.5 Ukraine \n", + "101 Other, specify 24.32 85.0 85.0 3.8 United States \n", + "102 Other, specify 34.06 70.0 70.0 5.0 Ukraine \n", + "103 NaN NaN NaN NaN NaN Ukraine \n", + "\n", + " Histologic_type FIGO_stage Race \\\n", + "0 Endometrioid IA White \n", + "1 Endometrioid IA White \n", + "2 Endometrioid IA White \n", + "3 Carcinosarcoma NaN NaN \n", + "4 Endometrioid IA White \n", + ".. ... ... ... \n", + "99 Endometrioid IA NaN \n", + "100 Endometrioid II NaN \n", + "101 Serous II Black or African American \n", + "102 Serous IA NaN \n", + "103 Serous NaN NaN \n", + "\n", + " Ethnicity Gender Tumor_Focality \n", + "0 Not-Hispanic or Latino Female Unifocal \n", + "1 Not-Hispanic or Latino Female Unifocal \n", + "2 Not-Hispanic or Latino Female Unifocal \n", + "3 NaN NaN NaN \n", + "4 Not-Hispanic or Latino Female Unifocal \n", + ".. ... ... ... \n", + "99 NaN Female Unifocal \n", + "100 NaN Female Unifocal \n", + "101 Not-Hispanic or Latino Female Unifocal \n", + "102 NaN Female Unifocal \n", + "103 NaN NaN NaN \n", + "\n", + "[104 rows x 12 columns]" + ] + }, + "execution_count": 22, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "original_columns = map(lambda m: m[\"source\"], harmonization_spec)\n", + "dataset[original_columns]" + ] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.10.12" + } + }, + "nbformat": 4, + "nbformat_minor": 2 +} diff --git a/examples/getting-started-jf.ipynb b/examples/getting-started-jf.ipynb new file mode 100644 index 00000000..d245e9b9 --- /dev/null +++ b/examples/getting-started-jf.ipynb @@ -0,0 +1,3547 @@ +{ + "cells": [ + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# Getting Started" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "First, import the `bdikit` library." + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [], + "source": [ + "import bdikit as bdi\n", + "import pandas as pd" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "In this example, we are mapping data from Dou et al. (https://pubmed.ncbi.nlm.nih.gov/37567170/) to the GDC format." + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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CountryHistologic_Grade_FIGOHistologic_typePath_Stage_Primary_Tumor-pTPath_Stage_Reg_Lymph_Nodes-pNClin_Stage_Dist_Mets-cMPath_Stage_Dist_Mets-pMtumor_Stage-PathologicalFIGO_stageBMIAgeRaceEthnicityGenderTumor_SiteTumor_FocalityTumor_Size_cm
0United StatesFIGO grade 1EndometrioidpT1a (FIGO IA)pN0cM0Staging IncompleteStage IIA38.8864.0WhiteNot-Hispanic or LatinoFemaleAnterior endometriumUnifocal2.9
1United StatesFIGO grade 1EndometrioidpT1a (FIGO IA)pNXcM0Staging IncompleteStage IVIA39.7658.0WhiteNot-Hispanic or LatinoFemalePosterior endometriumUnifocal3.5
2United StatesFIGO grade 2EndometrioidpT1a (FIGO IA)pN0cM0Staging IncompleteStage IIA51.1950.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal4.5
3NaNNaNCarcinosarcomaNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaNNaN
4United StatesFIGO grade 2EndometrioidpT1a (FIGO IA)pNXcM0No pathologic evidence of distant metastasisStage IIA32.6975.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal3.5
5United StatesNaNSerouspT1a (FIGO IA)pNXcM0Staging IncompleteStage IIA20.2863.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal6.0
6United StatesFIGO grade 1EndometrioidpT1a (FIGO IA)pNXcM0Staging IncompleteStage IIA55.6750.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal4.5
7Other_specifyFIGO grade 2EndometrioidpT1a (FIGO IA)pNXcM0Staging IncompleteStage IIA25.6860.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal5.0
8United StatesNaNSerouspT3a (FIGO IIIA)pNXcM0Staging IncompleteStage IIIIIIA21.5783.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal4.0
9United StatesFIGO grade 1EndometrioidpT1 (FIGO I)pN0cM0Staging IncompleteStage IIA34.2669.0WhiteNot-Hispanic or LatinoFemaleOther, specifyUnifocal5.2
\n", + "
" + ], + "text/plain": [ + " Country Histologic_Grade_FIGO Histologic_type \\\n", + "0 United States FIGO grade 1 Endometrioid \n", + "1 United States FIGO grade 1 Endometrioid \n", + "2 United States FIGO grade 2 Endometrioid \n", + "3 NaN NaN Carcinosarcoma \n", + "4 United States FIGO grade 2 Endometrioid \n", + "5 United States NaN Serous \n", + "6 United States FIGO grade 1 Endometrioid \n", + "7 Other_specify FIGO grade 2 Endometrioid \n", + "8 United States NaN Serous \n", + "9 United States FIGO grade 1 Endometrioid \n", + "\n", + " Path_Stage_Primary_Tumor-pT Path_Stage_Reg_Lymph_Nodes-pN \\\n", + "0 pT1a (FIGO IA) pN0 \n", + "1 pT1a (FIGO IA) pNX \n", + "2 pT1a (FIGO IA) pN0 \n", + "3 NaN NaN \n", + "4 pT1a (FIGO IA) pNX \n", + "5 pT1a (FIGO IA) pNX \n", + "6 pT1a (FIGO IA) pNX \n", + "7 pT1a (FIGO IA) pNX \n", + "8 pT3a (FIGO IIIA) pNX \n", + "9 pT1 (FIGO I) pN0 \n", + "\n", + " Clin_Stage_Dist_Mets-cM Path_Stage_Dist_Mets-pM \\\n", + "0 cM0 Staging Incomplete \n", + "1 cM0 Staging Incomplete \n", + "2 cM0 Staging Incomplete \n", + "3 NaN NaN \n", + "4 cM0 No pathologic evidence of distant metastasis \n", + "5 cM0 Staging Incomplete \n", + "6 cM0 Staging Incomplete \n", + "7 cM0 Staging Incomplete \n", + "8 cM0 Staging Incomplete \n", + "9 cM0 Staging Incomplete \n", + "\n", + " tumor_Stage-Pathological FIGO_stage BMI Age Race \\\n", + "0 Stage I IA 38.88 64.0 White \n", + "1 Stage IV IA 39.76 58.0 White \n", + "2 Stage I IA 51.19 50.0 White \n", + "3 NaN NaN NaN NaN NaN \n", + "4 Stage I IA 32.69 75.0 White \n", + "5 Stage I IA 20.28 63.0 White \n", + "6 Stage I IA 55.67 50.0 White \n", + "7 Stage I IA 25.68 60.0 White \n", + "8 Stage III IIIA 21.57 83.0 White \n", + "9 Stage I IA 34.26 69.0 White \n", + "\n", + " Ethnicity Gender Tumor_Site Tumor_Focality \\\n", + "0 Not-Hispanic or Latino Female Anterior endometrium Unifocal \n", + "1 Not-Hispanic or Latino Female Posterior endometrium Unifocal \n", + "2 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "3 NaN NaN NaN NaN \n", + "4 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "5 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "6 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "7 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "8 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "9 Not-Hispanic or Latino Female Other, specify Unifocal \n", + "\n", + " Tumor_Size_cm \n", + "0 2.9 \n", + "1 3.5 \n", + "2 4.5 \n", + "3 NaN \n", + "4 3.5 \n", + "5 6.0 \n", + "6 4.5 \n", + "7 5.0 \n", + "8 4.0 \n", + "9 5.2 " + ] + }, + "execution_count": 3, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "dataset = pd.read_csv(\"./datasets/dou.csv\")\n", + "\n", + "columns = [\n", + " \"Country\",\n", + " \"Histologic_type\",\n", + " \"FIGO_stage\",\n", + " \"BMI\",\n", + " \"Age\",\n", + " \"Race\",\n", + " \"Ethnicity\",\n", + " \"Gender\",\n", + " \"Tumor_Focality\",\n", + " \"Tumor_Size_cm\",\n", + "]\n", + "\n", + "dataset.head(10)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Matching the table schema to GDC standard vocabulary\n", + "\n", + "`bdi-kit` offers a suite of functions to help with data harmonization tasks.\n", + "For instance, it can help with automatic discovery of one-to-one mappings between the columns in the input (source) dataset and a target dataset schema. The target schema can be either another table or a standard data vocabulary such as the GDC (Genomic Data Commons).\n", + "\n", + "To achieve this using `bdi-kit`, we can use the `match_schema()` function to match columns to the GDC vocabulary schema as follows.\n", + "\n", + "The GDC schema contains XXX attributes and current SOTA is not able to handle ... explain why we need this model. point to a description of the model.\n", + "\n", + "Note: This step requires the model to be downloaded and it may take a few minutes" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Extracting features from 10 columns...\n" + ] + }, + { + "data": { + "application/vnd.jupyter.widget-view+json": { + "model_id": "3031a658aaca478184486c9c8cf567f7", + "version_major": 2, + "version_minor": 0 + }, + "text/plain": [ + " 0%| | 0/10 [00:00\n", + "\n", + "\n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + " \n", + "
sourcetarget
0Countrycountry_of_birth
1Histologic_typehistory_of_tumor_type
2FIGO_stagefigo_stage
3BMIaverage_base_quality
4Ageage_at_diagnosis
5Racerace
6Ethnicityethnicity
7Gendergender
8Tumor_Focalitytumor_focality
9Tumor_Size_cmtumor_width_measurement
\n", + "" + ], + "text/plain": [ + " source target\n", + "0 Country country_of_birth\n", + "1 Histologic_type history_of_tumor_type\n", + "2 FIGO_stage figo_stage\n", + "3 BMI average_base_quality\n", + "4 Age age_at_diagnosis\n", + "5 Race race\n", + "6 Ethnicity ethnicity\n", + "7 Gender gender\n", + "8 Tumor_Focality tumor_focality\n", + "9 Tumor_Size_cm tumor_width_measurement" + ] + }, + "execution_count": 5, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.match_schema(dataset[columns], target=\"gdc\", method=\"ct_learning\")" + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "Some weights of RobertaModel were not initialized from the model checkpoint at roberta-base and are newly initialized: ['roberta.pooler.dense.bias', 'roberta.pooler.dense.weight']\n", + "You should probably TRAIN this model on a down-stream task to be able to use it for predictions and inference.\n", + "100%|██████████| 17/17 [00:00<00:00, 25.70it/s]\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Table features extracted from 17 columns\n", + "Table features loaded for 734 columns\n", + "Distances (cosine): [1.10394392 0.98914557 0.92537964 0.94752893 1.05914744 1.08939152\n", + " 1.04157806 1.04617294 0.97803455 1.02611567 0.92811078 0.98646065\n", + " 0.92494871 0.82554179 1.08864448 1.11371916 0.9982571 0.88276508\n", + " 1.03046031 1.14162502 0.98299454 0.89779826 0.9763337 1.07523165\n", + " 0.89635589 1.06016441 1.0512307 1.02413479 0.91700193 1.08814005\n", + " 0.98184121 1.12561218 1.1200962 1.01722983 1.0703122 1.12627641\n", + " 1.07342407 1.05760935 1.1052211 1.20270863 1.05279379 1.08772562\n", + " 1.07630705 1.03543143 1.10607188 0.86132086 0.92440717 1.01018515\n", + " 0.93720262 1.00066075 0.9507775 0.8202722 0.93760846 1.00147017\n", + " 1.09045534 1.07474188 0.97043665 1.06990152 1.08130116 1.03859922\n", + " 1.09030101 0.94105161 1.01664633 1.01230161 0.99208111 0.83868857\n", + " 1.03597787 0.91045015 1.04946121 1.06219909 0.99042535 1.17921298\n", + " 1.06863905 1.11142212 1.1048234 1.04655936 1.07739838 1.02920307\n", + " 0.99854448 1.12527391 1.06252065 0.97119052 1.10264705 1.15662817\n", + " 0.93040146 0.92724415 0.80938487 1.10791158 0.97412993 1.11506726\n", + " 1.0649948 0.98802979 0.92422746 0.88855234 1.0779642 0.74885521\n", + " 0.91476221 1.05398798 0.93567329 1.10098667 1.14394185 1.10934022\n", + " 1.0617265 0.95444284 1.10284081 1.03876524 0.92237638 0.88370692\n", + " 0.94089827 1.13945938 0.99603632 0.93801217 1.00976941 0.88026456\n", + " 0.98282522 1.05058358 0.9860883 1.05932552 0.96329221 1.11555802\n", + " 1.06438735 1.00755368 1.0020513 1.01255041 0.77703186 0.95950253\n", + " 1.02155211 1.07603479 1.04840982 1.01180617 0.98880235 1.01487407\n", + " 0.98343204 1.02755002 1.08020208 0.48299481 0.59773088 0.96341324\n", + " 1.06461732 0.95000656 0.87175934 1.03878844 1.08659591 1.0836373\n", + " 1.08483535 1.10845733 1.09937026 0.99903025 1.11586622 0.94408797\n", + " 1.0390607 0.93682634 0.90696471 1.03023081 0.85651648 0.96370617\n", + " 0.94631951 0.96832422 1.09166494 0.98129671 1.09322019 0.96358111\n", + " 1.07313259 0.98367198 0.98307862 0.95333907 1.06234025 1.01072523\n", + " 1.01175053 0.92528214 0.98420634 1.20171161 1.13879293 1.0812003\n", + " 0.92027825 1.18482933 1.16669788 1.18738423 1.08630438 0.95013934\n", + " 0.843392 0.92903281 0.93205611 1.05871603 0.92614523 1.0222684\n", + " 1.10576144 1.10696842 1.04018278 1.14572734 1.0777618 0.98755742\n", + " 1.03651642 0.84308325 0.85711754 0.93358796 1.01399868 0.99781095\n", + " 0.84868517 0.8115899 0.85617877 0.92992486 1.0097102 0.91364532\n", + " 1.03334671 1.09466286 0.98169192 1.20903555 1.08876504 1.03504838\n", + " 1.0169913 0.73978803 0.93835376 1.01465904 1.01795997 0.98929862\n", + " 1.00141661 1.18443834 1.12905452 1.19624601 1.22307307 0.96228825\n", + " 1.11988601 0.95709925 0.82248892 0.99036264 1.15884998 1.23112248\n", + " 0.9625345 0.8891403 0.96666751 0.98046031 1.08053804 0.97642373\n", + " 1.01776627 1.09889763 1.18154788 1.16717484 1.14716145 1.15079721\n", + " 1.11800581 0.99361518 0.87273435 1.15907701 1.12392701 0.85336636\n", + " 1.24135173 1.07302095 0.85393121 0.99982827 0.97755079 1.06181857\n", + " 0.95620558 1.08254723 1.08192154 1.09986565 0.98880487 1.07818384\n", + " 0.90974765 1.04102068 0.80043169 1.09045143 1.04032956 1.03911996\n", + " 1.06043302 0.99891267 1.01993761 1.06014306 0.97428953 1.04603332\n", + " 1.06379186 1.14001071 1.07279578 1.08315104 0.99714045 1.05195085\n", + " 0.95903429 1.05745751 1.0901864 0.91190991 1.07615513 1.18597678\n", + " 1.03708796 0.93607662 1.08018328 0.90886744 1.02632555 1.11539912\n", + " 0.93305226 1.09629403 1.12550839 0.80241756 1.00335694 1.05990332\n", + " 0.98862793 1.06124536 0.84956406 1.05028204 1.03342671 1.11216918\n", + " 1.18161967 0.91032244 0.92101728 1.03122995 0.90456281 1.08494827\n", + " 0.86583913 0.98891987 1.00621366 0.9859491 1.00789291 0.99695072\n", + " 1.05242665 0.91534743 1.04813606 1.04154024 0.98333674 0.96281704\n", + " 0.67681641 1.04877961 0.92801401 0.81800031 0.78160584 1.11327994\n", + " 0.93739196 1.03289162 0.950401 0.90061114 0.97318549 0.99941559\n", + " 1.17323439 1.09968938 0.98071646 1.08068658 0.89749954 1.0458911\n", + " 1.12768754 0.87086419 1.18142233 1.01785715 1.04352135 1.05539603\n", + " 1.03877955 0.97201685 1.00169682 0.93782883 1.03205261 0.91170141\n", + " 0.96709506 0.90107587 0.98676919 0.90332241 1.05720276 0.98237062\n", + " 0.99980417 0.8101733 1.09432457 0.83165042 0.916839 1.10037032\n", + " 0.98565848 1.05722715 0.99255827 1.07289264 1.05466982 0.94580267\n", + " 1.00602562 0.89057042 0.88157763 0.94248613 0.87316393 1.05024452\n", + " 1.06235684 1.05657489 0.97377679 1.02328566 1.1440696 0.95296827\n", + " 0.95592317 0.95327472 1.22615593 1.09490717 0.96420086 0.94010969\n", + " 1.0026252 1.03672205 1.08922413 1.07104104 1.09634504 1.03859818\n", + " 1.06104437 1.04128541 0.99448946 0.98926661 1.04007511 1.06703309\n", + " 0.9727568 1.09338744 1.01456652 1.01050629 0.87937028 0.98677152\n", + " 0.9213385 0.91740966 0.88960243 0.63950099 0.79796862 1.08258118\n", + " 0.97580701 1.08796435 1.07144308 1.0008701 0.98971714 1.0170135\n", + " 0.82637575 0.94891125 0.71287148 1.09095092 0.87158585 0.73344138\n", + " 0.74428246 0.8422214 0.94960729 0.97114587 1.0489234 0.92288686\n", + " 1.01545398 1.03625752 0.85898154 0.98714234 0.94018373 1.12481494\n", + " 1.00119273 1.11810425 1.01326632 0.92469032 0.92980056 0.92727668\n", + " 0.9768303 0.87982122 0.91996929 1.11597287 1.1182633 1.05027882\n", + " 1.0392678 1.05293765 1.06230108 1.07126471 1.03459204 1.06692802\n", + " 1.06680581 1.07578711 1.09832561 1.06785771 1.09110073 1.072232\n", + " 1.11229952 0.73257871 0.97300813 1.01270747 0.97923095 0.9118936\n", + " 1.09798411 0.94435306 1.01845477 0.99266677 1.01822988 1.09277295\n", + " 1.00182525 1.05582098 0.94657405 0.86855501 0.80821068 0.78833387\n", + " 1.08846918 0.9472507 0.99033926 0.94183086 0.99213522 0.88507271\n", + " 0.84866263 1.04572674 1.02420407 0.92213033 1.0096699 0.83423474\n", + " 0.96515487 0.95035134 1.09420516 0.79956608 1.1221821 1.09863266\n", + " 1.13301877 1.13794924 1.07165549 1.0894248 1.04193192 0.99004886\n", + " 1.02817055 0.92258989 1.09123675 0.97055931 0.59536741 0.90337304\n", + " 0.83098943 1.07640774 1.09815195 1.02314465 0.99043423 1.0401784\n", + " 1.02778398 1.02133882 0.93815909 0.99128063 1.01307365 1.13949215\n", + " 1.23090947 1.10641274 1.07136228 0.92427334 0.83144663 1.08548376\n", + " 0.95114038 0.83579505 0.86071993 0.81958304 0.9292794 0.82915263\n", + " 1.000207 0.85948604 0.74625659 0.77283614 1.02212775 1.09282251\n", + " 1.03878331 0.92174042 1.02441132 1.08259223 0.92233169 1.05281913\n", + " 1.02193065 1.08589466 1.0385232 1.07859742 1.12202981 1.23649353\n", + " 0.97529974 1.07293888 0.89579682 1.12471282 1.05079676 1.06479434\n", + " 1.10388569 1.05454199 1.08868455 1.01155548 0.75796333 1.05108877\n", + " 1.01184285 0.9221099 1.04615021 1.23777058 1.01306592 0.87447406\n", + " 1.0056552 1.02213813 0.9628696 0.95176954 0.92195868 0.92589372\n", + " 0.94173811 0.95685675 0.936856 0.91443909 1.01259761 1.13564631\n", + " 1.08363326 1.13797314 0.93452242 1.04259107 0.9028165 1.03835095\n", + " 0.98988589 1.1532492 1.11142004 1.07981601 1.05956999 0.99421628\n", + " 1.09775178 0.98814517 0.97471704 1.17084441 1.00754041 1.06322675\n", + " 0.97705918 1.14216574 0.98732065 1.16913286 1.02460987 1.01453294\n", + " 0.85051374 0.90164168 0.75500349 0.93769278 0.99794825 0.67571398\n", + " 1.0697018 1.05094659 1.09084101 0.98633418 1.05337988 1.06408551\n", + " 1.09490506 0.91797621 0.92605609 1.13372687 1.00254043 1.04656997\n", + " 1.05881267 1.01958265 1.02282209 1.06794705 1.08145399 0.88131033\n", + " 1.18920747 1.02847709 0.98874637 1.15855894 1.11623241 1.11365645\n", + " 1.20280133 0.94716725 0.92448238 0.94697905 1.14526747 1.09326496\n", + " 1.02560705 0.93691396 1.05218455 1.01606935 1.01837208 1.01962053\n", + " 1.06717391 1.10738692 1.09184853 1.05044281 1.04978917 0.98921946\n", + " 1.07673994 1.10179733 1.13793322 1.20149239 1.16039546 1.19746403\n", + " 1.20251259 1.06963263 1.03985452 1.22618904 1.08471812 1.11429027\n", + " 1.02439602 1.18757639 1.15529956 1.18928422 1.08928541 1.13921254\n", + " 1.07755546 0.83842614 1.02978928 0.99067156 1.00432117 0.87413315\n", + " 0.9867311 1.01350094 0.92706312 1.08906537 1.0535204 1.08342161\n", + " 1.07943138 0.87403037 1.00562954 1.06666096 0.98922332 1.01362779\n", + " 1.08242069 1.04911772 0.97198061 0.90712231 1.01643754 0.98983685\n", + " 0.90092135 1.00485868 1.08817852 0.97958877 0.86093198 1.01270715\n", + " 1.06322836 0.87723456 0.75863909 0.85765349 0.86777915 0.91646267\n", + " 1.02064552 0.85726629 0.92339631 1.09390577 1.06696461 0.87206861\n", + " 0.84478102 0.79036395 0.94467204 1.13688743 0.79332937 0.9472456\n", + " 1.09285191 1.03885768 0.96989904 0.94336486 1.05973678 0.94492703\n", + " 0.93686459 1.02778933 1.10049902 1.06883023 1.07990608 1.09724396\n", + " 0.94154839 0.79522577 0.8649054 0.80816119 0.97008679 0.93918958\n", + " 0.6002156 0.98324281]\n", + "Distances (cosine): [0.79377923 0.84511488 1.04353481 1.02314329 0.7784911 0.81654495\n", + " 1.03197819 0.90592426 0.35509702 0.94065102 0.89271501 0.98496283\n", + " 0.9547756 1.08805272 0.897365 1.04788803 0.8024904 1.08267315\n", + " 0.73421394 0.90004238 0.72860143 0.93286173 0.65891005 0.78264038\n", + " 0.94245686 0.979172 0.95123953 0.95499859 1.12591085 0.90164634\n", + " 0.91346381 0.6735477 0.92113651 1.09470148 0.81614275 1.04215476\n", + " 1.02110069 0.92479474 0.81371484 0.77837078 0.7225767 0.87335875\n", + " 0.68908152 0.92316978 0.8921393 0.91176776 0.78991601 0.8811318\n", + " 1.04542312 1.00997 0.77236129 1.12375601 0.6917431 0.76603929\n", + " 0.86568562 0.88633667 0.82571964 0.76683808 0.86589262 0.88313874\n", + " 0.86195698 0.85292808 1.00466475 0.89765768 0.93442691 0.92721858\n", + " 0.99146445 0.92929562 0.88701728 0.87045559 0.87244789 0.8859439\n", + " 0.7950661 0.84497304 0.97596484 1.03572493 0.92607184 0.77031285\n", + " 1.03257968 0.74266591 0.98895215 0.9387461 1.1374819 0.94985102\n", + " 0.96559724 1.05106025 0.9960956 0.97224705 1.0142558 1.04205634\n", + " 1.14447632 1.07766628 1.11640751 1.05751929 0.84833912 1.12904737\n", + " 0.84903635 0.78581259 0.77479666 1.07084306 0.82596477 1.00735514\n", + " 1.03113807 0.93347599 1.18816811 0.80498206 0.87964455 1.08737448\n", + " 0.80550482 0.8649632 0.90401972 0.96314645 0.92341858 0.89219544\n", + " 0.90619392 0.89775644 0.83966164 0.95489495 0.789047 0.9660701\n", + " 1.10734387 0.75363676 0.82005423 0.99002856 1.11250083 0.69001789\n", + " 0.98490183 0.86574345 1.07533724 1.07308856 1.0469921 1.08064066\n", + " 1.06734506 1.07011555 1.06200297 0.99925887 1.06087619 0.90380705\n", + " 0.99727887 1.03840539 0.97528677 1.08132852 1.06277997 0.77771114\n", + " 0.84807426 0.88447404 0.88371258 0.76206474 0.77746081 1.08907374\n", + " 1.07253778 1.07206972 1.0523356 1.13440809 1.24218066 1.09568854\n", + " 0.97416499 1.02003222 0.94946839 0.89951724 1.05257643 1.09901662\n", + " 0.98286421 0.77847875 0.63512399 0.70523938 1.0832179 1.04548035\n", + " 0.99187503 1.08074362 0.89344592 1.0034867 0.9909526 0.81041342\n", + " 0.89015763 0.66499386 1.06710314 0.80135555 1.13733216 0.80041616\n", + " 0.82599972 1.08522738 0.93429613 0.96775723 0.73520166 0.99964495\n", + " 1.00993981 1.1639956 0.88179834 0.96874489 0.66140489 0.64523535\n", + " 0.78957577 0.85438113 0.73458138 0.85598959 0.83368027 0.86301537\n", + " 0.7660124 0.86197708 0.90880276 0.85669436 0.77694036 0.9057352\n", + " 0.59231941 0.68609393 1.06835234 1.02031892 0.67960027 0.67163289\n", + " 0.7363616 1.0320741 0.43935722 0.59450233 0.93307786 0.77621832\n", + " 0.6670274 0.97377734 0.88159051 0.97416993 0.89331681 1.06633403\n", + " 1.00066994 1.05958348 1.06498759 0.88399592 0.93896777 0.97457044\n", + " 0.91499811 1.11707712 0.70635897 1.06058492 0.61336059 0.8728544\n", + " 0.71294139 1.06531668 0.70917885 0.95035566 0.95033744 1.0365458\n", + " 1.06438182 0.73903954 0.84997651 0.95513918 0.92507693 0.92393026\n", + " 0.84476342 1.01050567 1.00748422 1.00667892 0.94270071 0.98604309\n", + " 0.93855739 0.83329911 0.82646335 0.81842873 0.87438944 0.88726777\n", + " 0.97547058 0.84512359 1.10120203 1.02079835 0.71546621 1.01857832\n", + " 0.93973101 0.35820669 0.43090605 0.78401955 0.62771236 0.90226637\n", + " 0.76915204 1.00559797 0.92189308 0.89765253 0.79622621 1.01323812\n", + " 0.39071492 0.66306826 0.71021017 0.897919 0.6684526 1.01278676\n", + " 0.88893569 1.1586956 0.82209324 0.94833964 0.98303217 0.67593659\n", + " 0.91106865 1.05392563 1.03817585 1.04336623 0.68085444 0.99961924\n", + " 0.96949003 1.16263646 0.76239217 0.79888488 1.00826539 0.65290545\n", + " 0.89017268 0.8767825 0.80246884 0.84308219 0.88660654 1.02854207\n", + " 0.45099801 0.51045045 0.61736395 0.69347606 0.77163913 1.04047237\n", + " 0.80225443 0.64174002 0.9183555 0.60762186 0.80518997 0.80724265\n", + " 0.9311875 0.88302012 0.81055845 1.02207594 0.998325 0.91300033\n", + " 0.93917786 0.75640397 0.97842832 0.887164 1.13279897 1.08077639\n", + " 1.07270541 1.1161289 1.02500912 1.10343557 0.95162515 0.98434637\n", + " 0.86856111 0.93023513 0.97793608 1.07024577 1.06574188 1.01717099\n", + " 0.90693823 1.02026594 0.87813848 1.00040276 1.04674674 1.05922604\n", + " 1.09390171 1.19395564 1.03198038 0.95640955 0.77978228 0.87773987\n", + " 0.70468028 0.84569914 0.6919281 1.13930737 0.64204632 0.87013306\n", + " 0.75911492 0.96781477 0.92518759 0.91522132 0.57432383 0.74084981\n", + " 1.07830669 0.93686931 0.91512978 0.84141006 0.6925752 0.90580502\n", + " 0.81058632 0.80628637 0.96072791 0.89623029 0.83895134 1.03635416\n", + " 1.01291041 0.92958626 1.10036607 0.8433536 0.97620536 0.84480909\n", + " 1.00115351 1.02835772 0.84315595 1.04671078 0.94514952 0.87565808\n", + " 0.97878669 0.71712046 0.86761036 0.82366785 1.12816417 0.54338535\n", + " 1.23133379 0.8443738 1.10201507 1.06371922 1.1610075 0.98761391\n", + " 1.03295178 1.01961894 1.12641414 1.02359875 1.11129017 0.89457424\n", + " 0.91085043 0.96179961 1.0685417 1.11330743 0.90323326 0.95654209\n", + " 1.11409259 0.842797 1.17587809 0.82179262 0.95036271 0.91799227\n", + " 1.01248933 1.04471321 0.9903102 1.049056 0.96286264 1.04060533\n", + " 0.86361363 0.83808872 0.89448728 1.10685404 0.86857824 0.97841358\n", + " 0.87713798 1.01134646 1.02557009 0.98177378 0.89329245 0.87442265\n", + " 0.88196559 0.85971519 0.721007 0.87166598 0.92914679 0.99903028\n", + " 0.91516036 0.99242205 1.04030249 0.93457009 1.12654171 0.98011889\n", + " 1.13392578 1.03740723 0.88850686 1.13402036 1.02018061 0.99807728\n", + " 1.12903986 0.95930094 1.03601175 0.99623213 0.98926687 0.95030544\n", + " 0.94833886 0.65108075 0.8044386 1.05373274 0.72222036 1.02082896\n", + " 0.71968653 0.98134342 1.05812225 1.06579809 1.07216369 1.24263739\n", + " 0.87659589 0.9299808 1.00500719 0.86633974 0.42979173 1.02669588\n", + " 1.11188179 1.03184952 0.89349942 0.72075745 1.08112645 0.80162359\n", + " 1.06419238 0.60704796 1.09044025 1.0206672 1.09525445 0.72892774\n", + " 0.92014092 0.93213931 0.93654482 0.86436494 0.98646593 1.03365684\n", + " 1.06527873 1.05485911 0.8088211 0.89212748 1.052226 0.93851732\n", + " 1.01277612 1.00429412 0.58876666 0.80042127 0.90607665 0.93391198\n", + " 0.81000413 0.90904291 0.96353846 0.96339143 1.0178133 0.98240888\n", + " 1.10318396 0.74415823 0.74536339 0.95256385 1.09742215 1.08817483\n", + " 0.95291813 1.0956764 1.1501048 1.1250106 1.13184386 1.13985464\n", + " 1.0318899 1.18980659 1.16978245 1.14108042 0.83408944 0.83920952\n", + " 0.76184941 1.15382051 0.96616938 1.05072708 1.18019412 0.99463747\n", + " 0.83821661 1.07351592 0.70237043 0.91422827 1.05700333 1.05083962\n", + " 0.8355144 0.87578291 0.99749883 0.92657083 0.80012114 0.93679934\n", + " 0.77833677 0.91498076 0.91073303 0.9011318 1.07441864 0.72016241\n", + " 0.80542364 0.89466006 0.61541166 0.81631268 0.38344518 1.17734014\n", + " 1.1182954 0.94961365 0.95259953 0.952703 1.09238144 0.86694939\n", + " 0.94411681 1.15486972 1.03022934 1.04562338 0.74619344 0.8862082\n", + " 0.9988765 0.81226441 0.92434132 1.07845713 1.03631469 0.86565418\n", + " 0.91509932 0.90095683 0.78828725 1.13765517 0.72209985 0.78015085\n", + " 0.86745739 0.85392562 0.81134805 0.94901872 0.74771744 0.87664448\n", + " 0.9487431 0.94695172 1.04571049 0.77078626 0.7014322 0.88622092\n", + " 0.89697477 0.96418283 1.11117632 1.02270486 1.15232261 1.16404042\n", + " 0.54437643 0.83872541 1.09410234 0.99114682 1.10898017 0.92804036\n", + " 1.03804605 0.87468663 1.17750823 1.09443191 1.01713943 0.84109882\n", + " 1.14320478 1.12006731 1.0101061 1.10864952 0.800911 0.78575326\n", + " 0.90786821 0.72341924 0.92863417 0.97965122 0.94196835 0.94552929\n", + " 0.89450745 1.10964551 1.10833115 1.17161076 0.95751038 0.7275626\n", + " 0.76739801 1.01137415 1.02126176 0.76580038 0.90275726 1.07719558\n", + " 1.17301883 1.07834549 0.91515952 1.305638 0.96508431 0.80298527\n", + " 0.97446924 1.00291281 0.82523247 0.86439797 0.93464455 0.84776342\n", + " 1.02528123 1.04426563 0.9677613 1.03695951 0.97564 1.01285923\n", + " 0.90810489 1.00402457 1.03319965 1.05486037 0.8442116 1.17975675\n", + " 1.08875158 0.97354155 0.72205246 0.67981724 0.6979567 0.87086303\n", + " 0.90533805 0.33496469 0.41450096 0.87710891 0.70909963 0.78122453\n", + " 0.84276757 0.65895297 0.75780094 0.86242535 0.52307143 0.73491328\n", + " 0.67820557 0.79631289 0.98021096 1.00517558 0.94751527 0.76520278\n", + " 1.04040576 0.74359536 0.79090394 0.71056795 0.90715007 0.70978451\n", + " 0.73903295 0.95632175 0.99005478 1.11526055 1.15154528 1.03789063\n", + " 0.96348991 1.02205416 0.96080271 0.97691643 0.97032511 0.74486693\n", + " 1.08987067 1.19891628 0.88815843 0.9470519 1.15958828 1.0976111\n", + " 1.05219107 0.94376756 0.78063034 0.73139362 0.93125614 0.67141133\n", + " 0.34501842 0.72245062 1.01867693 1.084953 1.01753439 0.95348023\n", + " 0.8840522 1.06160859 1.08587714 0.94988497 0.8976729 1.13208249\n", + " 0.6990244 0.87452904]\n", + "Distances (cosine): [1.04534682 0.83449225 1.01881871 1.20422125 0.88390344 0.50633979\n", + " 0.80166418 0.93899871 0.89463848 1.1067674 1.14282617 1.24423385\n", + " 1.13441173 1.14921422 0.85064511 0.63975606 0.73705031 0.82303183\n", + " 0.82085985 0.93002399 0.72586019 0.75952515 0.74355475 0.89328724\n", + " 0.92281185 1.08914824 1.06464707 1.01587924 1.00087741 1.10455693\n", + " 0.86397886 0.93540472 1.00359993 0.9734764 0.93067889 1.14574301\n", + " 1.09539759 0.90983352 1.10573127 1.1043833 1.03928411 0.68565249\n", + " 0.61442803 1.04485213 0.65680382 0.89262063 0.76547883 0.60197329\n", + " 0.78169802 0.94285067 0.83374858 0.80524751 0.79574854 0.98955976\n", + " 0.55378029 0.76972653 1.01082235 0.75126782 1.06095287 1.14661249\n", + " 1.17649452 1.16253703 0.7743184 0.93578214 0.97200366 1.07798857\n", + " 0.81883198 0.88189776 1.01626758 0.61770969 0.75411874 0.81292612\n", + " 0.66018628 1.00594605 1.03370743 1.06801374 0.99700062 1.04980414\n", + " 0.62596288 1.00655983 0.69305425 0.83221884 0.60974065 0.68457561\n", + " 0.76201676 0.78958613 0.95512487 1.11593361 0.80679338 0.78837296\n", + " 0.90380893 0.79525611 0.98962489 0.94698909 0.72460231 0.90784453\n", + " 0.72610109 0.7055898 0.81496508 0.65447061 0.66881266 0.79862517\n", + " 0.52202087 0.70694762 1.14093738 1.01215033 0.67769648 1.02014617\n", + " 0.67189287 0.84493309 1.05786808 0.57816003 1.00712903 0.94309685\n", + " 0.79630824 0.60873189 0.70025097 0.43265677 0.80141504 0.93795547\n", + " 0.80381175 0.70583708 0.53975243 0.98473081 0.91992756 0.77637376\n", + " 0.92485565 0.88907916 0.64588226 0.68398393 0.89283598 0.75041362\n", + " 1.03002239 0.71664971 0.90646761 0.91122764 0.94715906 0.93144261\n", + " 0.95053633 1.0270605 0.99795198 1.16379636 0.87516108 0.77825713\n", + " 0.86977061 0.92890916 0.75890635 0.88593467 0.82083743 1.18285073\n", + " 1.25116541 1.05649097 0.9897406 0.87597708 0.9480377 1.16550924\n", + " 1.04141481 1.12804056 1.18002195 1.16660758 1.22788299 1.1823521\n", + " 1.18655586 0.89444166 1.10514281 1.13772722 1.01222265 1.21479608\n", + " 1.00363198 1.12667252 1.16725641 1.24152515 1.29195014 1.02317669\n", + " 0.98778808 0.86404917 0.48948512 0.95015464 0.59619479 0.8409988\n", + " 0.67208096 0.80926598 0.92303296 0.45661038 1.03248007 0.81232052\n", + " 1.13639843 0.92835202 0.85845298 0.89437612 0.69007434 0.88936411\n", + " 0.59448023 0.91749758 1.00103566 1.00698363 0.81120153 0.94210757\n", + " 1.01495156 1.03067602 1.05664033 1.11954223 0.98658274 0.89921381\n", + " 0.88758646 0.9705695 1.09133338 1.0132542 0.97851028 0.84431074\n", + " 0.84197033 0.88272569 0.73502187 0.72238603 1.21699013 0.88887705\n", + " 1.05416695 0.91501961 0.92663417 0.83927019 0.8549431 1.30954559\n", + " 1.26947635 1.27551206 1.08353029 0.82193126 0.81914111 1.07841823\n", + " 0.76491672 0.79130334 0.81250934 0.74624751 0.94339441 0.83428629\n", + " 0.73914685 0.61665867 1.00500602 1.14556565 1.12166183 1.07128113\n", + " 1.04778574 0.87217059 1.03076114 0.80669378 1.00805261 1.10661284\n", + " 0.95224318 0.81725271 0.82773444 1.10932531 1.09989331 0.80221199\n", + " 1.09616763 1.18055908 1.13904818 1.15372267 1.19273367 0.93040204\n", + " 1.21037939 0.83637363 0.99369737 0.95276903 0.6048119 1.01960734\n", + " 0.95055756 0.78817089 0.85710299 1.03757536 0.95435961 0.58501312\n", + " 1.14008095 1.29330558 0.97783305 1.14624861 1.13438343 1.07621417\n", + " 0.70333287 0.61067955 0.52483881 1.01329219 0.33860219 1.20829933\n", + " 0.78375426 0.94405198 0.77110729 0.93390717 1.11165004 0.65952427\n", + " 0.71068666 0.56275184 0.54643214 1.06807586 0.62405856 0.77378632\n", + " 0.96282782 0.76329189 1.10285218 1.13040578 1.1274189 0.84568461\n", + " 0.90721833 1.12338988 0.903244 1.01658071 0.87568573 1.31391162\n", + " 0.74933227 0.70116898 0.88362748 0.88814001 0.97449582 0.99530486\n", + " 1.06269711 1.01613418 0.93361863 0.67527353 0.95088384 1.04925904\n", + " 1.12397471 0.78389179 0.95054343 1.23150494 1.01947201 0.63399173\n", + " 0.93272953 1.02730567 0.80193835 0.80967406 0.9087958 0.97602037\n", + " 1.13166399 0.78308303 1.11553547 1.09524507 0.99322541 1.21201326\n", + " 0.76516201 1.00481471 0.89099116 0.86756071 0.93614261 0.97262688\n", + " 1.1457529 1.12048512 1.00009068 0.95412648 1.0259919 1.06717773\n", + " 0.98429951 1.04934987 1.07239443 1.06048006 1.14849222 1.01428635\n", + " 1.14203967 1.10677876 0.74371732 0.94638552 0.89067333 0.8295882\n", + " 0.99296511 0.81018981 0.86617648 1.14017717 0.84511235 1.02163549\n", + " 0.88385637 0.80771544 1.05851662 0.88042816 0.90649228 1.05013947\n", + " 0.8841403 0.91753887 0.93927526 1.14956387 0.93105488 0.97519571\n", + " 1.0120718 1.03055226 1.18835806 1.19517603 1.02360029 0.88943948\n", + " 1.01156252 1.07922678 0.91323345 0.92382424 0.8995658 0.60822399\n", + " 0.7007303 1.12502956 1.14517069 0.79196489 0.76838794 0.74046771\n", + " 0.92923849 0.81664571 0.94835659 0.92631228 0.89996565 1.18064574\n", + " 1.17790481 1.10844171 1.17163504 0.92763731 1.01930924 0.81923484\n", + " 0.70817812 0.96831796 0.82864176 0.95956478 1.06173846 0.79418962\n", + " 1.26873413 1.04670846 1.07273889 0.81975422 0.82206944 1.11371286\n", + " 1.12708361 1.12332817 0.98001306 1.14902377 0.99258595 0.86893115\n", + " 0.55300158 0.85702421 1.06022226 1.00246518 0.54888009 0.51069006\n", + " 0.84943509 0.51257126 1.06074035 1.06351955 0.99853674 1.01770872\n", + " 0.89748343 1.07005492 1.12751406 1.09755518 1.10279629 0.97398764\n", + " 1.14648714 1.08517691 1.0993587 0.98512419 0.99980694 1.17311488\n", + " 0.9474967 0.99599463 0.70839356 0.87928033 1.00521035 1.16537576\n", + " 1.01851286 1.14014696 0.8994348 0.98425736 0.64800205 1.21153679\n", + " 0.73376358 0.68546077 0.85940779 1.10767382 0.60017958 0.97613384\n", + " 0.84600848 1.13848258 0.99005333 0.93091833 0.93911247 1.04523212\n", + " 1.24269866 0.87507664 0.53619816 0.86124004 0.79781198 0.82471069\n", + " 0.86982312 1.1247093 0.90858526 0.80614262 0.94079238 0.83152756\n", + " 1.08690995 0.7769924 0.84533395 0.90643842 0.82027779 0.9803175\n", + " 1.05138565 1.04845194 1.11024093 1.09649319 1.20142497 0.78523217\n", + " 0.83501554 1.09263272 0.63797344 0.72377907 0.96401287 0.97809939\n", + " 0.91145021 0.88962243 0.68506623 1.07969542 1.20732737 1.157425\n", + " 0.87283946 1.09849403 1.06423024 0.94716247 1.09491586 0.96100161\n", + " 1.00484268 1.15389972 0.97082682 1.08822931 0.94049406 0.52066138\n", + " 0.81735354 0.92857756 1.17488624 0.79962358 0.69812638 1.11325965\n", + " 0.96402694 1.35227801 1.26508196 1.24526343 0.82565041 0.97077339\n", + " 1.09024583 0.99405924 1.03222308 0.99686687 0.93302086 1.01724994\n", + " 0.99297733 0.88871991 0.86493841 1.16392706 0.98768534 0.9925434\n", + " 1.00338824 0.38941011 1.15951719 1.09821636 0.83267225 0.58208267\n", + " 0.6284753 0.93208455 0.74056203 0.50512028 0.99414033 0.74490123\n", + " 1.04879451 0.90993356 0.63688804 0.86070677 0.79579031 1.00465159\n", + " 0.76445638 1.13761298 1.13520614 1.05156847 1.13718849 0.95721637\n", + " 1.16612984 1.01416769 0.93725312 0.97166071 1.09056446 0.70421969\n", + " 0.84515732 0.50105773 0.85111894 0.91583942 0.99594441 1.02559688\n", + " 0.98760969 0.70824655 0.93072976 1.22663842 1.01180287 1.035419\n", + " 0.82134197 1.04550548 1.00768757 0.84894967 0.53990856 0.90240712\n", + " 1.00219131 0.80319395 0.95815204 0.65537896 1.12173456 1.11943658\n", + " 1.11260734 1.08731833 1.03902341 1.07550324 0.66833685 1.26655488\n", + " 0.92451854 0.97226992 0.97394181 1.00776892 1.01328708 0.98373986\n", + " 0.81837284 0.78109509 0.85626548 0.76689324 1.0184734 1.068447\n", + " 1.19118289 1.2117979 0.9383075 1.19423213 0.82954493 1.01808435\n", + " 0.99733926 1.0611633 1.28882417 0.71170285 0.98044159 1.06359306\n", + " 1.03308093 1.11940472 1.24407655 1.19354694 1.05741523 0.94838573\n", + " 0.81631737 0.85772831 0.76025462 0.68924807 1.04575369 1.0928422\n", + " 1.06723443 1.06767989 1.21044634 1.09300157 1.05354402 1.00005243\n", + " 0.78183794 0.89168471 0.98514474 1.1966679 1.26227033 1.27078105\n", + " 1.31079156 1.05884836 1.25154656 1.28569648 0.99333707 1.22597844\n", + " 1.12550864 1.35532285 0.98780398 0.96869749 0.99187543 0.83959069\n", + " 0.69962162 0.6918884 1.09632142 1.05100187 1.12010049 0.6295884\n", + " 0.93327709 0.83275444 0.86167754 0.99813643 1.018953 1.05497157\n", + " 1.09611737 0.94565549 0.68851967 1.18237034 0.9440074 0.87380451\n", + " 0.99798593 1.1026808 1.11748527 0.90385294 0.80314876 0.76724933\n", + " 0.8027015 0.80739205 0.8973715 0.76179977 0.7991677 0.81283183\n", + " 0.85274101 0.8957888 0.87920984 0.92612447 1.01476137 0.85340603\n", + " 0.84018572 0.9632537 0.83335895 0.96299633 1.22374821 0.76416537\n", + " 0.92072461 1.23773021 0.93192888 0.58715839 1.14727755 1.20347987\n", + " 1.18039958 0.97774155 1.22645986 0.6827297 1.19051546 0.64655241\n", + " 0.75181214 1.0046754 0.99152322 1.05537546 0.97851677 0.92098297\n", + " 1.10707632 0.96631477 0.9165961 0.87464713 1.01050989 1.14624962\n", + " 0.84930686 0.67767044]\n", + "Distances (cosine): [0.82825715 0.62359626 0.99418404 0.77766986 0.52605233 0.97594027\n", + " 1.15272241 0.91784397 0.64261686 1.00216108 0.90878798 1.00009768\n", + " 0.96607713 1.27259229 0.60202528 1.08765909 0.93217597 0.86445893\n", + " 0.49823048 0.40703214 0.87464899 0.72162649 0.4367457 0.33916609\n", + " 1.02669423 1.17972145 1.1201921 1.19320868 1.24966553 1.04306109\n", + " 1.09800226 0.7227302 0.88590823 1.05822346 0.9403877 0.9666244\n", + " 1.0888294 0.83058004 0.85776046 0.89501822 0.88941475 1.00946694\n", + " 0.89103029 1.0951134 0.84080234 1.07193999 0.93938561 1.15777243\n", + " 1.16803023 1.15079601 0.70980863 1.30431199 0.63826874 0.43676509\n", + " 0.90275083 0.98834466 1.10892418 1.07810193 0.93052711 0.94197685\n", + " 1.02993145 1.2278289 1.08871582 0.97114848 1.03142096 1.00676926\n", + " 0.92681605 0.74661862 0.63355352 1.04526187 0.98797063 0.97088538\n", + " 1.06254358 1.01402486 1.02042732 0.97910534 1.00469039 0.89597561\n", + " 1.14698009 0.80079943 1.03314213 0.90101546 1.12577638 0.92307883\n", + " 1.03040616 1.07563806 1.15012739 0.92063261 0.91749398 1.14584539\n", + " 0.9825686 0.90139875 1.082403 1.01582277 1.02625036 1.1349136\n", + " 0.82069843 0.98121924 0.69913487 1.16099023 0.86032993 0.7438835\n", + " 1.01787291 0.98210699 1.06326245 0.7673374 0.95463315 1.20817819\n", + " 0.76018983 1.01412988 0.86505305 1.1523242 1.12402759 0.74792604\n", + " 0.67874265 1.0516867 0.69720518 1.15872328 1.11857394 1.02277201\n", + " 1.16639151 1.08794582 0.94959075 0.96594236 1.17103131 0.95288232\n", + " 0.96886764 0.98076841 1.26025723 1.15271478 1.05524933 1.15845134\n", + " 0.97560478 1.21231191 1.00898488 1.16022135 1.2215126 0.77371375\n", + " 0.9358835 1.04143417 1.07548799 1.05472926 0.9278626 1.09783274\n", + " 0.96140159 1.02268277 0.63609512 1.07861788 1.00091304 1.08764272\n", + " 1.11733778 1.07516763 1.16333391 1.23496303 1.22913734 1.06533215\n", + " 1.00636774 1.02115576 1.02640577 1.09262709 1.02311979 1.06341619\n", + " 0.9671017 0.73401764 0.73118012 0.79022826 1.15174238 0.89872528\n", + " 1.15151796 1.04456151 0.95007271 0.8404472 0.70162236 0.71018546\n", + " 1.07650111 0.93134183 1.08044276 0.82809769 1.16115854 0.78143183\n", + " 0.9814125 1.02492827 0.71366339 1.02863109 0.61822106 1.00530082\n", + " 1.01031585 0.99182608 0.96562725 1.01296653 0.9137607 0.87613672\n", + " 1.00130004 1.03108626 0.91844041 0.93955793 0.95558833 0.85446313\n", + " 1.00057275 1.05435784 0.88478012 0.56609228 0.91957895 0.83366194\n", + " 0.47526659 0.33926172 0.98850638 1.05348425 1.01894807 0.96831791\n", + " 1.00614492 1.09645548 0.77776391 0.97286892 1.11355171 0.81814163\n", + " 0.86631941 0.94860733 0.84877635 0.92157772 0.84346681 1.0462804\n", + " 0.97938001 0.90605716 1.16448537 1.05686045 1.03184418 0.97171237\n", + " 0.94274689 1.09993827 0.94048533 1.08097811 0.41002363 1.10082138\n", + " 0.99476886 1.09940623 0.60839587 1.08686121 1.09582832 1.00061523\n", + " 0.94066168 0.46424254 1.03569256 0.80625447 0.93183815 1.1316273\n", + " 0.9218113 1.1285146 1.06333175 0.86953332 0.88405937 0.93055432\n", + " 0.76205487 0.88429242 0.90281743 0.86966408 0.84140403 1.21853639\n", + " 0.89812965 1.13285731 1.28525964 0.68303351 0.82489298 1.01671146\n", + " 1.03504462 0.8139996 0.7193002 0.97953702 0.97664268 1.22034105\n", + " 0.72608399 0.94264687 1.09306173 0.91910223 0.86787975 0.96599085\n", + " 0.72039849 0.9624797 0.88905622 0.72705659 0.86267864 1.00789605\n", + " 1.10051618 1.33434683 0.96097071 0.87129107 0.85598058 1.07526694\n", + " 1.20328568 1.069503 1.05567501 0.91168245 0.86862345 1.13475984\n", + " 1.0971439 1.12814873 1.00420693 0.94750218 1.05140952 0.80333984\n", + " 0.80500859 1.19949303 0.83217579 0.93004902 0.96807189 0.95374445\n", + " 0.67138639 0.78518247 0.90052132 0.52288245 0.71866269 1.14238894\n", + " 0.79645181 0.71069047 0.77103636 0.79982669 0.67306628 0.77688846\n", + " 1.05550589 0.87513748 0.74746807 0.92117694 1.05094447 0.99906812\n", + " 0.84833297 0.78409731 0.93032099 0.95759547 1.06283122 1.05323048\n", + " 0.77159876 1.0908598 0.75632751 0.83182145 0.95962812 0.70511334\n", + " 0.93631869 1.09873938 0.8298377 1.13219114 0.96074165 0.70836411\n", + " 0.81717877 0.93681523 0.86200076 0.93720661 0.81000767 0.93400173\n", + " 1.02848276 1.10122319 1.00569868 1.01669831 0.90273601 0.96579946\n", + " 0.56110175 0.87641592 0.96077639 1.198048 0.56502224 0.91334753\n", + " 0.46392885 0.8003465 0.96563718 0.92670587 0.94552031 0.9968988\n", + " 1.11027497 0.99240151 1.05084806 1.00386988 0.84580533 0.8390339\n", + " 1.02654363 0.9147707 1.09931415 1.02729013 0.98379606 1.150763\n", + " 1.19327609 0.91482492 0.93135086 0.64925219 1.10511593 0.86997062\n", + " 0.97376226 1.01923433 0.88503922 0.9455116 0.69023453 1.08579463\n", + " 1.11892574 0.91176808 0.99747274 0.88165637 1.16195827 0.93096989\n", + " 1.06974043 1.16113558 1.0889458 1.07351041 1.20063954 1.12683425\n", + " 0.97239608 1.22248048 1.20187668 1.03069703 0.90565416 1.01290694\n", + " 0.95699106 0.75252228 0.97335244 1.05768348 0.83087484 0.87892526\n", + " 1.01044125 0.92092891 0.98431736 0.70414992 1.22473795 1.04345974\n", + " 0.98736442 1.25925532 1.23203181 1.04584218 0.87131524 0.93970377\n", + " 0.86258367 0.92224477 0.94608036 1.02466252 1.0414659 1.01672579\n", + " 0.8289922 1.00909338 0.73982749 1.07790465 1.03660743 1.00930707\n", + " 1.18434106 0.96273017 0.71154956 0.88693425 1.05186138 1.24266013\n", + " 0.89988265 0.98277378 0.91887344 0.90927767 1.16103685 0.86872051\n", + " 1.20603789 1.14009558 1.00044432 1.12493823 0.88591544 1.00015528\n", + " 1.1333014 0.89949119 0.92780633 0.88619928 0.92469826 0.84752799\n", + " 0.81274509 0.72236557 0.85631052 0.98513816 0.90545158 0.95847087\n", + " 0.69600982 0.99807273 0.92991193 1.10141191 1.09119059 1.27737642\n", + " 0.89132212 1.05595663 1.02025448 0.82015451 0.73454542 0.90792156\n", + " 1.24091625 0.83978481 1.02305678 0.90162498 0.9191056 0.91504499\n", + " 0.78459253 0.74918244 0.96153998 0.81756089 0.92711034 0.83946778\n", + " 1.04898197 1.06791171 1.01173785 1.1269901 0.83430914 1.03448334\n", + " 1.07285949 1.01476408 0.82373434 0.82461459 1.10580022 1.00176251\n", + " 1.07294887 0.89258661 0.83536603 1.03263071 0.80102573 1.01887429\n", + " 0.99509323 0.85969717 0.93811553 0.82849231 0.99228274 0.97501169\n", + " 0.88329543 0.84270955 0.89739778 1.04762181 1.26460847 1.01089502\n", + " 1.07846523 1.2286828 1.12350657 1.16070574 1.11603206 1.16141438\n", + " 1.13822465 1.20912851 1.21936441 1.0770431 0.98094572 0.76027234\n", + " 0.80966056 1.18574133 0.92702767 1.16617825 1.33797189 1.06796747\n", + " 0.95890457 1.14422138 0.9723609 0.81272344 1.04506258 0.923107\n", + " 0.96438104 0.94144166 0.61132969 0.95025584 0.92340204 1.05109962\n", + " 0.91649787 0.93611124 0.99987965 1.07933297 0.96571552 0.83580764\n", + " 0.99250019 0.77488103 0.75294748 0.91164421 0.80239226 1.1285267\n", + " 1.07165725 1.12870814 0.92801381 1.22235412 1.19196182 0.95610004\n", + " 0.86140024 1.17373702 1.07709108 1.06669327 0.62821346 0.64157675\n", + " 0.64690112 1.02322703 0.75325086 0.9081749 0.91942439 0.93889173\n", + " 0.72908857 0.97963826 0.86427103 1.09352116 0.66712905 0.68176539\n", + " 0.89188979 0.80140292 0.42833517 0.90241119 0.97305315 1.0379237\n", + " 0.83332893 0.84282262 0.98976113 1.08149677 0.75939386 0.80612504\n", + " 1.14469373 1.06698947 1.15352081 0.88976082 0.98962925 1.0866615\n", + " 0.62453253 0.62897427 1.03858627 1.02272007 0.96603381 0.87818425\n", + " 0.90201579 0.8489842 1.24221042 1.03636471 0.89936046 0.62107697\n", + " 0.85662281 0.84166876 1.08351185 0.78318576 0.93560128 0.9823907\n", + " 0.98315868 0.79788953 0.85460683 0.86620276 0.98268212 0.95649977\n", + " 0.9441433 1.02038212 1.00121709 1.04167492 0.80050287 0.79724619\n", + " 0.65358291 0.84397532 1.04102503 0.860017 0.70427594 0.93523037\n", + " 0.98285865 0.94082113 0.94876811 1.08225523 0.93924591 0.65699445\n", + " 0.94709814 0.97692793 0.6634247 0.7704766 0.85389506 0.86278256\n", + " 0.80900481 0.84602752 0.77154793 0.87354668 0.87871923 0.84424871\n", + " 0.77064003 0.75335991 0.91117674 0.85454361 0.96827834 0.97673803\n", + " 0.85661908 1.00551129 0.72746672 0.65621899 0.72150498 0.85311281\n", + " 0.82152782 0.59890798 0.48932766 0.75121662 0.82344239 0.70734347\n", + " 0.7984398 0.47430001 0.72101164 0.70462178 0.57875548 0.84946097\n", + " 0.6865923 0.76073119 1.23225192 1.00343381 0.99084845 0.86849289\n", + " 0.78272645 0.48760116 0.35429222 0.80698988 0.72581087 0.41524584\n", + " 0.32238085 1.03558281 1.07087362 1.14821339 1.15382093 1.06582094\n", + " 0.97257575 1.05934412 1.04148047 0.93952419 1.13682602 1.12304585\n", + " 1.07665594 1.14737215 1.09105077 1.08893984 1.06117688 1.10570784\n", + " 1.06389163 0.87927196 0.96261583 0.83070419 1.04584175 0.83055773\n", + " 0.6631257 0.78156765 0.97618 1.03462887 0.92666629 0.98247521\n", + " 1.04704954 1.12961627 1.17864863 0.95675306 0.9824265 1.04215771\n", + " 0.63971859 1.17446935]\n", + "Distances (cosine): [0.9843836 0.64189458 0.90593079 0.79249187 0.66220272 0.94477823\n", + " 1.07966571 1.02839812 0.73932091 1.16446425 0.9566686 1.03778053\n", + " 1.0063827 1.21377877 0.66284692 1.0082713 0.97556555 0.52656377\n", + " 0.57850922 0.72423347 0.88460245 0.37235654 0.47205801 0.69014156\n", + " 0.97562761 1.14955377 1.14437032 1.2218012 1.25368152 1.12185805\n", + " 1.12432393 0.93577513 0.95293207 0.99020976 1.04840308 1.01781334\n", + " 1.08593222 0.97274349 1.12249192 0.9980201 1.0095202 0.95951341\n", + " 0.87168549 1.07886419 0.7031066 0.99943714 0.89798015 1.1010914\n", + " 0.99537304 1.01618712 0.58705232 1.05620562 0.50077789 0.58255489\n", + " 0.82086668 0.89000573 1.23077364 1.18570584 1.08559501 0.97264989\n", + " 1.02866667 1.15927942 0.97989779 0.99409706 1.06593524 1.01014897\n", + " 1.03675038 0.64835662 0.80866247 0.96832619 0.93246239 0.8973635\n", + " 1.13842324 1.00043224 1.08062984 1.01919734 1.10387608 1.01121687\n", + " 1.06932854 0.97332574 1.01364969 0.98024851 1.02712782 1.04413479\n", + " 1.07613066 0.99822492 1.17472228 1.13119282 0.9367471 1.20057992\n", + " 0.98377842 0.87806223 1.22230199 1.06360002 1.01410797 1.09743965\n", + " 0.79309421 1.00763369 0.58935065 1.05336568 0.8410245 0.78776487\n", + " 0.88248371 0.86184386 1.11962109 0.98990857 0.77192114 1.22500389\n", + " 0.84453 1.02013696 1.0556784 0.95420396 1.20658511 0.73529331\n", + " 0.57036819 0.8689323 0.5111902 1.01977806 1.24868239 1.10604913\n", + " 1.15433459 1.18435492 0.96226188 1.111127 1.22632863 0.79438884\n", + " 1.01590886 1.0031663 0.95096534 0.97223761 1.00104243 0.97741541\n", + " 0.86896093 0.99797549 0.89847764 1.16762214 1.19413817 0.83550321\n", + " 1.21142109 1.15562368 1.2676541 1.06724068 0.94236087 0.96609591\n", + " 1.08193639 1.03991504 0.65180306 0.98228905 1.04131332 1.20932155\n", + " 1.23185131 1.08652365 1.31822257 1.35050143 1.24590583 1.17828721\n", + " 1.11959092 1.16431423 1.14422474 1.13232935 1.07857799 1.04718823\n", + " 1.07551025 0.72773944 0.77541706 0.80834952 1.36396117 0.94218219\n", + " 1.22162312 1.10530331 1.14627518 1.13764938 1.0571938 0.77623045\n", + " 1.10878855 1.06758429 1.02900245 0.93668347 1.01881986 0.84680792\n", + " 0.93254506 0.90952951 0.8774964 0.85875556 0.82844085 1.07682099\n", + " 1.08129938 0.90533428 0.92649404 1.01456979 0.86685045 0.92299542\n", + " 0.93358202 0.83343163 0.96014196 0.79330087 0.92108871 0.80741422\n", + " 0.79263589 0.97605407 0.72508693 0.81616306 0.92128541 0.41635968\n", + " 0.44151244 0.55180216 1.02946865 1.05767777 1.11464884 0.95124177\n", + " 1.04443689 1.10460824 0.76077977 1.1264093 1.07911551 0.81222949\n", + " 0.87120135 0.95134161 0.84092628 0.85948464 0.81697379 1.10242688\n", + " 1.10211234 1.01333358 1.05114689 1.10152714 1.14737589 0.84494606\n", + " 0.90992254 1.01222933 0.94263248 0.91956159 0.67786354 1.20395035\n", + " 0.97697508 1.05404691 0.83978822 1.11741763 1.13767748 0.97652644\n", + " 0.91100251 0.56690178 1.02991411 0.7917062 1.00874637 1.23871541\n", + " 1.07177679 0.93677616 0.97564353 0.8507179 1.05803345 0.95607792\n", + " 0.84545519 0.9227359 0.9212579 0.91554157 0.83113876 1.1923238\n", + " 1.0696676 0.94417126 1.23954563 0.66025434 0.66371408 0.92933243\n", + " 1.05191405 0.70583156 0.77096309 0.92565032 0.89567264 1.16021345\n", + " 0.87717301 1.12691545 0.9539623 1.27023523 1.01716912 1.02398832\n", + " 0.69783536 0.99212493 0.90493951 1.08541575 0.88986987 1.12718312\n", + " 1.05789904 1.30849866 0.96479983 0.78907689 0.89783608 1.08820307\n", + " 1.05781154 0.92352531 0.87843075 0.88799135 0.69894404 1.04122657\n", + " 1.23422815 1.0412038 1.03411524 0.9525182 1.0389714 1.04381681\n", + " 0.88973071 1.16845719 0.77779044 1.05136145 1.04080579 1.03617468\n", + " 0.60952009 0.77576797 0.80625352 0.5104701 0.70350876 1.24059473\n", + " 0.96393193 0.6474535 0.7848625 0.70969958 0.65421422 0.85617924\n", + " 1.01282895 0.84334948 0.61030441 0.88309157 0.8843204 0.90002286\n", + " 0.77088033 0.91921854 0.98024783 0.9351283 1.18699458 1.26779642\n", + " 0.91634862 1.01337535 0.72435218 0.78541166 0.82291789 0.73472356\n", + " 0.87775186 1.05222362 0.76885186 0.99704827 0.90883699 0.89866107\n", + " 0.98895154 0.89422094 0.71589601 0.61528712 0.7406647 0.66479577\n", + " 0.6536945 0.72668448 0.65918091 0.98313019 1.01294371 1.00298639\n", + " 0.84315047 0.92624275 1.03541803 1.19693977 0.6962603 0.91367807\n", + " 0.60173728 0.85320189 1.03331591 0.95841739 1.02828298 1.08055231\n", + " 1.00971033 0.94513338 1.00809466 1.09412685 0.91625782 1.01063681\n", + " 1.14509843 1.07231933 1.14319765 1.06630079 0.87427445 1.15428864\n", + " 1.23779381 0.95138567 0.90741926 0.77010252 1.27657708 0.7329845\n", + " 0.91101229 1.01743997 0.82554836 0.93051701 0.72785781 1.0362052\n", + " 1.10469363 0.8502979 1.0135665 0.90547056 1.13742154 0.89444714\n", + " 0.94069295 0.94737478 1.12372953 0.9981688 1.01930019 0.95886181\n", + " 1.00038794 1.08091066 1.07327638 0.80932165 0.97448227 0.96139058\n", + " 0.85134366 0.81641544 0.90246415 0.86849652 1.02056207 0.81319095\n", + " 1.12291417 1.03096982 1.00572031 0.75541752 1.15559026 1.05746973\n", + " 0.97046561 1.07311871 1.03540914 0.93738694 0.91960416 0.91549344\n", + " 0.77142563 1.06414381 1.06645475 0.95528143 0.92393675 0.93751906\n", + " 0.91844055 0.94742418 0.83928196 0.79828877 0.90023393 0.91280385\n", + " 0.91748293 0.87544472 0.80097471 0.92333537 1.18813912 1.0975477\n", + " 1.02083086 1.07875334 0.93416027 1.00695775 1.04152021 0.98213238\n", + " 1.11999259 1.17064133 1.0133391 1.03358366 1.10498921 1.22231824\n", + " 1.11530428 0.92492925 0.60176275 0.59014792 0.89561103 0.99168126\n", + " 0.89557092 0.64489547 0.76785093 0.88603004 0.95860873 1.10609864\n", + " 0.67585931 1.07127985 0.88183997 1.11939602 1.09868306 1.2297142\n", + " 0.96960963 1.12692403 0.85206204 0.85361052 0.68326669 0.93073932\n", + " 1.14412584 1.04117489 0.86774485 0.91484424 0.95113871 0.85235129\n", + " 0.7908208 0.71875255 0.95647977 0.72807514 0.9303925 0.95089418\n", + " 1.08119579 1.09440353 1.07894049 1.05293919 0.94642214 0.83276288\n", + " 0.87746039 0.91792415 0.74408039 0.85948045 1.07132263 1.0275898\n", + " 1.14952088 0.80068487 0.91232118 0.96771368 0.80176459 0.95120046\n", + " 0.89215046 1.10175175 1.15415147 0.88742421 1.0765616 1.15348347\n", + " 1.01046585 0.9918624 1.09010237 1.07639014 1.22209062 0.95110557\n", + " 0.97332116 1.10179184 1.06165335 1.06004232 0.96643951 1.20377603\n", + " 1.27209199 1.27507605 1.21734571 1.20105465 1.00598862 1.01407634\n", + " 1.1024922 1.08476061 0.89385057 1.24350476 1.33614864 0.97768745\n", + " 0.99854881 1.20053354 1.03664058 1.02198765 1.1751063 0.93507605\n", + " 0.90496305 0.9113967 0.73267285 1.05790457 0.88084307 1.06244818\n", + " 0.94189695 1.04643744 1.04626054 1.12103184 0.86484108 0.83454725\n", + " 1.0875436 0.63742305 0.62041663 0.87994253 0.76856027 1.02443639\n", + " 1.00836862 0.95501685 0.95095894 1.04834397 1.03928442 1.02266042\n", + " 0.81323979 1.14047071 1.21070102 1.13473206 0.78075967 0.72336825\n", + " 0.66329469 0.87432563 0.78670005 0.86447706 0.80925242 0.91070465\n", + " 0.66784916 0.95176667 0.93927099 1.05362356 0.81598555 0.85979789\n", + " 0.85119325 1.01129707 0.59141727 0.91367738 1.01017776 1.17273021\n", + " 0.83761587 0.66803774 0.91196983 1.08026153 0.75582063 0.83068391\n", + " 1.17708562 1.16757662 1.14914777 0.9579413 0.79671284 1.12197871\n", + " 0.91173966 0.62519659 0.8890841 1.09345559 0.81607688 1.02506059\n", + " 0.83555397 0.95072444 1.05983872 1.01367652 0.90969718 0.73972481\n", + " 0.86668259 0.85281475 0.90405681 0.8145662 0.90461598 0.95171919\n", + " 1.05453061 0.96154925 0.94726478 0.82021558 1.11051102 1.09100204\n", + " 1.02486189 1.08631664 1.03762444 1.09353708 1.0579452 1.09413795\n", + " 0.56185933 0.809503 1.03033872 1.09057123 0.79190034 1.0861469\n", + " 1.06588143 0.9840204 1.11141795 1.02940047 0.9959645 0.83339356\n", + " 0.9637354 1.04161391 0.81159611 1.02444811 1.0224339 1.06902052\n", + " 1.14854207 1.08576482 1.05361037 1.11167726 1.06020578 1.14511333\n", + " 1.04934783 1.04952923 1.12036461 1.09039358 1.15533596 0.98584058\n", + " 0.82862253 1.03223004 0.93724356 0.92768615 0.95693477 0.74347306\n", + " 1.12405729 0.68981612 0.71261161 0.94167083 1.08521864 0.89939115\n", + " 0.96427403 0.69449424 0.89527541 0.98806704 0.82307468 1.19577153\n", + " 0.95781928 1.01084809 1.30869366 0.96608008 1.03841682 0.94995681\n", + " 0.45992677 0.59315619 0.69846593 0.86500162 0.38541379 0.48498631\n", + " 0.61918384 0.99942432 1.13856427 1.15599024 1.1070595 1.07840485\n", + " 1.03767312 1.06947302 1.03078803 1.20657479 1.12993119 0.91677506\n", + " 1.14409553 1.22381333 1.1946243 1.0626919 1.09643623 1.07376261\n", + " 1.12685922 0.88921523 0.93287532 0.71724748 0.97411937 0.63414431\n", + " 0.57780102 1.03370353 1.24375592 0.9236417 1.21003137 0.93991023\n", + " 1.13382357 1.03320155 1.15811684 0.98110558 0.9193943 0.98266731\n", + " 0.62870188 1.12300935]\n", + "Distances (cosine): [0.87690332 0.92317216 1.0425743 1.01004323 0.85344631 0.84774546\n", + " 1.05791853 1.11478178 0.82422152 0.94763475 0.9745045 1.13254928\n", + " 0.95943654 0.9896267 0.835505 0.99435745 0.26341436 0.78265025\n", + " 0.57642215 0.92727898 0.26484969 0.72579199 0.51594446 0.76698775\n", + " 0.76479389 1.00135408 1.04803815 1.13723827 1.16451173 1.16655497\n", + " 1.15770067 0.72637731 1.12441194 0.76742551 0.67117495 1.2020931\n", + " 1.12479107 1.15692161 0.99716345 0.95649667 0.86363399 0.98505575\n", + " 0.86761193 1.02134378 0.88653213 0.95724649 0.89437555 0.92806972\n", + " 0.93419474 1.13561531 0.60201109 0.89059517 0.63669616 0.94573762\n", + " 0.68344775 0.69579425 1.19732999 1.09690219 0.98203295 1.04265711\n", + " 1.14215032 1.23489304 0.91433629 0.805704 0.96087518 1.05956514\n", + " 0.82202733 0.82975769 0.9781637 0.99174646 0.93227987 1.05702294\n", + " 1.01889296 1.01467559 1.06097893 1.15348761 0.8826236 0.85669084\n", + " 0.60870645 1.03254867 0.87379885 0.85766081 0.79634073 0.66295546\n", + " 0.76443129 0.92905325 1.14913172 0.96918161 0.77950721 1.0268828\n", + " 0.93664399 0.64782367 0.79050822 0.98077493 1.02569014 0.7915314\n", + " 0.8089744 0.72330508 0.64791805 0.72337487 0.68797874 0.84070829\n", + " 0.79828483 0.86773295 1.11137128 0.89695017 0.62135514 0.9034587\n", + " 0.70089997 1.02695391 0.99622321 0.63896899 1.12708358 0.75094769\n", + " 0.59753181 0.79469656 0.61109364 0.78728662 0.77331129 1.0898665\n", + " 0.99349327 0.86693951 0.77446146 0.81924899 1.01934989 0.94236487\n", + " 0.94576703 0.79018552 0.91147566 0.73015892 0.74976755 0.73626589\n", + " 0.68901524 0.70080596 0.85143237 0.88036916 0.96068609 0.7893807\n", + " 1.03675925 0.97340899 0.86439062 1.09641065 0.98725001 0.65801885\n", + " 0.9458336 0.7961588 0.75427084 0.61799947 0.91924908 1.12511711\n", + " 1.06797077 0.96016192 0.95540977 0.80285499 0.84942986 1.20450548\n", + " 1.0201984 0.96395321 0.9631759 0.92062963 1.04146732 1.12242637\n", + " 0.97849005 0.85031071 1.03263935 1.08905424 1.04540113 1.09772885\n", + " 0.97162126 0.95683356 1.11230627 1.11875957 1.11644855 1.09779756\n", + " 0.92731834 0.80371262 0.75318826 1.09696501 0.77641174 0.89917148\n", + " 0.91159696 0.71259482 1.00284356 0.7366436 0.81354728 0.90174872\n", + " 1.20044 0.84155623 0.81703605 0.93485689 0.94617007 0.76627945\n", + " 0.88322145 0.96730846 0.77618514 1.00023434 1.11458712 1.01698237\n", + " 0.62710009 0.39911462 0.4619611 0.76364943 0.42092111 0.88328805\n", + " 0.66906405 0.88806082 1.21965492 1.12706117 0.7467624 0.85086964\n", + " 0.81257871 0.9430722 0.86244566 0.93295783 1.12285111 0.83449736\n", + " 0.91534863 0.91923288 1.05073488 0.90969685 0.81142773 1.27259883\n", + " 1.23676622 1.20261847 1.09322814 1.05981547 1.13607295 0.92979561\n", + " 0.82750346 0.76346154 0.81155805 0.77238385 0.78434612 1.06913608\n", + " 0.32301759 0.80589192 0.94838328 1.19496086 1.13776105 1.27495916\n", + " 1.200166 0.62990857 1.00523499 0.76959155 1.07183627 1.06220251\n", + " 0.90390376 0.80149597 0.90752828 0.94742703 0.86576441 0.99063707\n", + " 1.00094921 1.09652178 1.0619237 1.09423689 1.06596165 0.94649289\n", + " 1.04266602 0.85019426 0.95304358 0.72738928 0.7212436 0.67977618\n", + " 0.74871885 0.67316986 0.78910666 0.92365561 0.81629186 0.67962168\n", + " 0.93350766 1.15566132 1.04541209 1.12086324 1.02300564 1.22199361\n", + " 0.76721994 0.84023959 0.71466106 0.97022266 0.69942731 1.16690792\n", + " 1.10293717 1.07147337 1.06542137 1.12275698 1.16442995 0.72435854\n", + " 0.93140104 0.64620375 0.64690931 1.24263277 0.63875329 1.00663606\n", + " 0.95918781 0.81876694 0.86503838 0.85771607 0.91329075 0.91113259\n", + " 1.05829353 1.19187281 1.04925155 1.00953407 0.99584508 1.14119163\n", + " 0.72199764 0.8528871 0.43960865 0.61334877 1.08363804 0.99065808\n", + " 0.94134668 0.94560526 0.88357699 0.66733619 0.79132486 1.1870028\n", + " 1.04158419 1.05210641 0.6833739 1.21099477 0.95422214 0.90870254\n", + " 0.89418562 0.86462509 0.94662497 0.73427667 0.93220227 0.96667605\n", + " 1.0743047 0.80542906 1.0674335 0.99601692 1.00533342 1.01691356\n", + " 0.92236917 0.93969152 0.76356966 0.81105923 0.90311176 0.96821955\n", + " 1.02349221 0.9222341 0.85263295 0.85167775 0.91312021 0.90068203\n", + " 0.91096726 0.90713546 0.93385638 0.90212395 0.82319982 0.84064907\n", + " 0.96398139 0.99004118 1.05599377 0.93612722 0.47532773 0.84635026\n", + " 0.96394201 0.94589457 0.86988437 0.98898635 0.84546478 0.54910394\n", + " 0.87038368 0.7224472 0.94093337 0.81480473 0.55635164 0.9628762\n", + " 1.01198147 1.06236465 0.74350216 0.96503938 0.77122396 0.65357417\n", + " 0.78342463 0.79869559 1.10455939 0.99888694 0.62106453 0.83017652\n", + " 0.81299309 0.79810814 0.82263634 0.81150758 0.76990163 0.92188467\n", + " 0.89765486 0.65988882 0.57619615 0.86775375 0.60921966 0.57994597\n", + " 0.86847027 0.73488462 0.79678766 0.95175093 1.06580326 0.97055694\n", + " 0.84258348 0.90802306 0.95012052 0.80684013 1.01153979 1.13283347\n", + " 0.90457354 0.90922432 0.91214707 0.82302905 1.11611876 0.99856177\n", + " 1.10182915 0.976954 0.96392594 0.77701588 1.03345851 0.98745349\n", + " 1.08403244 1.17370996 1.09584785 1.05088665 1.00566409 0.85821945\n", + " 0.97959363 1.09946718 1.0542369 0.98482146 0.97513083 0.76632546\n", + " 0.97815744 0.78129417 0.97362777 1.03715023 0.97138203 1.01832681\n", + " 0.85269976 1.05485616 1.04152052 1.11115951 1.17633058 0.88280189\n", + " 1.11249105 1.07944241 1.08123364 0.91768877 1.06287553 1.19497083\n", + " 0.97266473 1.15115342 0.90833198 0.8071837 0.95783315 1.10748218\n", + " 1.07750718 1.03142902 0.92818649 0.95642888 0.90328747 1.10965506\n", + " 0.81579149 0.62228957 0.94446476 0.98751003 0.85155726 0.94207884\n", + " 0.87600769 0.90576798 0.96102863 0.99940886 1.03839776 1.00119487\n", + " 1.07990372 1.199895 0.65669287 0.95146196 0.7826262 1.02856173\n", + " 0.84298371 1.16002006 0.8575816 0.92135508 0.82156448 0.92916826\n", + " 1.03563443 0.84777377 0.77087883 0.7546757 0.82164484 0.80119746\n", + " 1.04559517 0.95358598 1.06369571 0.8966855 1.13041663 1.11089484\n", + " 1.10078121 1.15688725 0.74993792 0.74659025 0.98183839 1.03250932\n", + " 1.0474255 0.72552018 0.79118507 0.75977613 1.03464075 1.15753696\n", + " 0.92560585 1.0642587 1.07534222 0.78052277 0.93391381 1.22347534\n", + " 0.98229415 0.96892642 0.98153387 0.92891812 0.97706766 0.81114871\n", + " 0.88870776 0.93352461 1.10345809 0.86292989 0.77477245 1.11318783\n", + " 1.02210576 1.24904486 1.2102 1.1709875 0.98040439 1.04546482\n", + " 0.84193649 1.20207511 0.89676501 1.1846675 1.14353879 0.87470245\n", + " 0.89589876 1.22424656 0.978207 1.11042409 1.07964041 1.01872475\n", + " 0.87340834 0.781625 0.981001 0.87801525 0.82245312 0.94874581\n", + " 0.9327673 1.11923474 0.9453229 0.80534342 0.80294895 0.99245819\n", + " 0.81689325 0.80259435 0.69601662 0.84201884 0.72183549 0.93858045\n", + " 1.03532938 0.96894923 0.85832166 0.95246337 0.99838937 0.92699134\n", + " 1.06163427 0.87724479 0.92091255 0.70367245 0.92670097 0.59518325\n", + " 0.87726232 0.62793077 0.97201475 1.0715886 0.7934568 0.83930146\n", + " 0.87000832 1.05752424 1.14226832 1.1988814 0.79616412 0.82727091\n", + " 0.80329166 0.8707058 0.96394329 0.8110409 0.87715008 0.96189318\n", + " 0.85060154 0.90189729 0.93831211 0.96097526 0.9735498 1.04338571\n", + " 0.93009813 1.0821682 1.146727 0.75691052 0.72119961 1.06239313\n", + " 0.80914131 0.74985947 0.81031191 0.93276681 0.98332272 1.1377163\n", + " 0.81172144 0.82492761 0.81140181 0.8803619 0.84329988 0.9420492\n", + " 1.06099268 1.07570296 1.05184496 1.09196297 0.98125219 0.9130756\n", + " 1.02073677 1.0329944 1.15077694 0.85135127 1.06146554 1.11877369\n", + " 0.95533437 0.9547424 1.10839323 0.97151628 0.96805231 1.09339818\n", + " 0.58031016 1.07898664 1.09664186 0.9670847 0.925491 1.2002371\n", + " 1.15604225 1.13667383 1.22151273 1.05083122 0.98286264 0.91653363\n", + " 1.19388587 1.03960047 0.948397 1.10523817 1.12482324 1.05482468\n", + " 1.14557121 1.16403261 1.15585675 1.21223499 1.064555 1.16281828\n", + " 1.00785306 1.26268356 1.06275759 1.03860986 0.94149705 0.77292103\n", + " 0.80469667 0.73754905 0.98293335 1.0091822 0.90553896 0.85127832\n", + " 0.91397818 0.76767765 0.75768003 0.90627337 0.74472657 0.90086253\n", + " 0.89124741 0.88860119 0.89080734 1.13540797 0.83287743 0.80292313\n", + " 0.98837231 0.84125298 1.06301125 0.95461878 1.15299413 0.26237172\n", + " 0.75379072 0.55615359 0.76287212 0.26210771 0.71638969 0.59588792\n", + " 0.80032471 0.812189 0.96562687 1.07752524 1.00049483 1.00166179\n", + " 1.19862933 1.14695425 1.0239438 1.04264658 1.06432255 0.69139717\n", + " 0.87943712 1.07672026 0.73721459 0.9689589 1.15067512 1.04779745\n", + " 1.07526442 0.96899584 0.99448907 0.63236125 1.08408556 0.6104677\n", + " 0.7434803 0.99565699 1.03377629 0.94766023 1.03657986 0.7953639\n", + " 0.89971243 0.70413588 0.92634361 0.84282139 0.87024392 1.0335405\n", + " 0.77742679 0.98328883]\n", + "Distances (cosine): [0.85027926 0.86938012 1.03683104 0.93396593 0.8517932 0.94105315\n", + " 1.05185122 0.98357043 0.6889369 0.82534499 0.82756996 0.99155765\n", + " 0.8591207 0.95481632 0.72335077 1.16213324 0.39311616 0.85113179\n", + " 0.68181206 0.7110691 0.32714476 0.74950675 0.50597078 0.59148818\n", + " 1.13618308 1.0751477 1.08494275 1.15588561 1.21703612 1.09229737\n", + " 1.22772676 0.74541898 0.99537383 1.08301708 0.7719991 1.2673668\n", + " 1.29601781 1.09502218 0.92060473 0.95244188 0.9003239 1.03527477\n", + " 0.88353811 1.18839738 0.9782056 0.87005954 0.78291293 1.03204861\n", + " 1.05101714 1.12013283 0.63235195 1.15736129 0.57690555 0.71678475\n", + " 0.88331787 0.97702656 1.08756655 1.09786376 0.87406384 1.10102927\n", + " 1.10679952 1.23524452 1.13013882 0.91488497 1.03290282 0.99177589\n", + " 1.07098037 0.8866828 0.63595477 1.14710751 1.01764648 1.03670659\n", + " 1.05925665 1.16699974 1.14528347 1.20818163 0.8848487 0.77824417\n", + " 0.83458589 1.03717495 0.8338719 0.81858591 0.97475573 0.86293719\n", + " 0.99027256 0.98472132 1.06839995 0.76686355 1.07205268 1.13862054\n", + " 1.08742281 0.88902881 0.90157418 1.11888862 1.14182568 0.94743857\n", + " 0.97681878 0.75899276 0.6860931 0.86154734 0.74076582 0.85256853\n", + " 1.12834968 0.96745575 1.18487517 0.95941859 1.00375795 1.11513943\n", + " 0.60465444 1.08303481 0.8709872 1.01517412 1.12674414 0.65305199\n", + " 0.76860847 0.87617751 0.79768465 1.02952933 0.80883198 1.00838442\n", + " 1.05343604 0.8496953 0.85484933 0.89222036 1.05620511 0.90522922\n", + " 1.05477776 0.99812039 1.23255629 1.15360367 1.16457896 1.14415615\n", + " 0.93441402 1.13777546 1.076951 0.99928051 1.08488403 0.97635222\n", + " 1.00829312 0.93837662 0.96770957 1.23418307 1.03426783 0.85361792\n", + " 1.16321725 1.02621389 0.69063431 0.81572021 0.83985867 1.08783342\n", + " 1.0867341 0.8626893 1.1525388 1.09966724 1.16703542 1.05996631\n", + " 0.95968976 1.01634708 0.93089716 0.92166262 0.97848943 0.9477233\n", + " 0.92458992 0.78628398 0.81121962 0.86823849 1.11546237 0.9741085\n", + " 1.10063656 1.01523513 1.12429974 0.94522958 0.9109397 0.85137022\n", + " 0.91244166 0.83739388 0.9724517 0.88045476 0.95705168 0.63978677\n", + " 0.85534454 1.01368285 0.74003621 0.81096514 0.59718569 0.9891135\n", + " 1.15483858 0.94546531 0.67865811 0.77638446 0.83900927 0.6044996\n", + " 0.81423667 1.08989162 0.84878913 0.98037734 1.0660677 0.95228607\n", + " 0.74551822 0.42819857 0.5576637 0.63572994 0.34702285 0.7266914\n", + " 0.44258671 0.56388731 1.14961341 1.03713846 0.85068439 0.76216518\n", + " 0.72275349 1.04865963 0.72335149 0.88473588 1.10212243 0.99281162\n", + " 0.96660555 0.89133524 1.00696983 0.97575266 0.85100919 1.06082798\n", + " 1.14323778 1.00592128 1.11127407 1.0889305 1.18066474 0.97920373\n", + " 0.97855612 0.98374869 0.80052119 1.1310446 0.59916008 1.1188179\n", + " 0.57081713 0.90736488 0.84585526 1.13490855 1.09712425 1.29729615\n", + " 1.24281219 0.71446248 1.06192263 0.89072942 1.2140021 1.10342741\n", + " 0.99146013 1.23824971 0.91822548 0.70005851 0.71270316 1.09665363\n", + " 0.73310157 1.08179519 1.05067207 1.10393656 0.91482319 1.02106412\n", + " 0.94810558 1.00711245 1.02297042 0.68378228 0.80749057 0.88823184\n", + " 0.83499626 0.74388235 0.77309171 0.96262951 0.95852926 0.93513562\n", + " 0.835913 1.04542186 1.13393442 0.96653228 1.05198983 1.04425016\n", + " 0.55653433 0.93147509 0.80912184 0.70413703 0.64467075 1.20363512\n", + " 1.03791868 1.12699871 0.94457998 0.95038199 0.94620442 0.74093163\n", + " 1.00299753 0.99193895 0.9975173 1.19284892 0.85770929 1.11650213\n", + " 1.0066536 0.93668807 0.6704685 0.93389572 1.02309013 0.81718488\n", + " 0.88154057 1.23801894 0.92456003 0.86186722 0.77331893 0.9939457\n", + " 0.64174372 0.72377115 0.43626118 0.59091922 0.90293833 1.07042179\n", + " 0.8379341 0.75709428 0.96890438 0.87841952 0.9071956 1.03903105\n", + " 0.97887195 1.01157404 0.71607757 1.14711585 0.99643463 0.9160738\n", + " 0.9353228 0.76006652 0.76936986 0.77566505 0.98197923 0.98231696\n", + " 1.0087327 1.00753523 0.97618373 1.02026899 0.93817117 0.90539471\n", + " 1.01906619 1.13624189 0.81406669 1.12513335 1.04411064 0.88813539\n", + " 0.85213981 0.83084233 0.7175158 0.83277285 0.8038537 0.72851699\n", + " 0.95856793 0.90199422 0.98021475 0.7022062 0.7032129 1.05965112\n", + " 0.72680256 0.83988739 0.95099984 0.98674743 0.37678638 0.97116994\n", + " 0.74590307 0.84577326 0.93745513 0.96039029 0.68139275 0.56277253\n", + " 0.74609263 0.64179324 0.74799084 0.63941424 0.3360463 0.7319595\n", + " 0.9550492 1.01735961 0.92800106 0.87212077 0.85984275 0.63335458\n", + " 0.80417072 1.04066257 1.06743627 0.76014011 0.68453769 0.76493058\n", + " 0.83685836 0.85757753 0.79520803 0.90836483 0.70692402 1.08913506\n", + " 1.06378164 0.71296864 0.5318079 0.88301624 0.85924498 0.66850444\n", + " 1.1328257 0.98739837 0.96280933 0.97722016 1.12476375 1.05816086\n", + " 0.855959 1.08532668 1.07847039 0.82852503 0.87629673 1.07277836\n", + " 1.00826189 0.68605534 1.16066891 1.0873077 1.03248433 1.07966462\n", + " 1.02193057 0.87083919 1.07382113 0.65354791 1.15822648 0.84640656\n", + " 0.99107444 1.11825103 1.08210912 1.01025104 1.09530516 0.80685421\n", + " 1.01924788 1.07529628 0.89897595 0.98772309 0.97264781 0.86259672\n", + " 0.98748185 0.87393031 0.82504837 1.0270059 1.01653905 1.04659229\n", + " 1.0734658 1.04216928 0.84955863 1.00619812 1.05350906 1.08560793\n", + " 0.89940555 0.94052923 0.8351545 0.88200004 1.06095702 0.95970161\n", + " 1.07798487 1.0716473 1.00131074 0.942993 0.88192364 0.89124349\n", + " 1.05945407 0.81093137 0.83879878 0.95733917 0.99515782 0.92032881\n", + " 0.8921864 0.78552956 0.85329483 0.98895064 0.74702144 0.81640171\n", + " 0.85908358 0.90393817 0.97537186 0.93114848 0.89509852 0.98623485\n", + " 0.92585133 1.20349028 0.7323127 0.74032764 0.7564327 1.01443265\n", + " 0.97885389 0.97989887 0.90224117 0.86856419 0.82330849 0.83748068\n", + " 0.87422685 0.64199869 0.7872544 0.78728476 0.83714168 0.69140304\n", + " 1.06532385 0.96316269 0.94815467 0.89910071 0.93332216 1.29074759\n", + " 1.32872837 1.11016799 0.77276424 0.80032956 1.1318285 0.97072455\n", + " 0.99090964 0.87192794 0.90485336 0.89851838 0.93839196 1.16214866\n", + " 0.97348263 0.83532783 0.94960877 0.93747749 0.92744469 1.13610403\n", + " 0.88025365 0.83481303 0.90118769 0.78969614 1.04819635 0.92573888\n", + " 1.00078029 0.96802616 1.14078596 0.99972058 1.06267382 1.1191855\n", + " 1.10333854 1.21054898 1.23412189 1.13198852 0.86667811 0.87345249\n", + " 0.63608226 1.23648673 1.12384691 1.123744 1.14385893 0.96818703\n", + " 1.03337979 1.24278098 0.90601802 0.86946576 1.06703089 1.13886802\n", + " 1.01091832 0.927081 0.77625446 1.01827333 1.0899561 0.96763183\n", + " 1.05111291 1.0969471 1.02208003 0.9545395 0.84521509 0.95792995\n", + " 0.94820432 0.79963067 0.58647168 0.79589575 0.79506977 1.04827178\n", + " 1.17253642 1.05111677 0.84953223 1.11923266 1.11159929 0.92045392\n", + " 0.9396734 0.96776654 0.9906914 0.88226451 0.84051188 0.60937509\n", + " 0.8012998 0.95082409 0.88211756 0.98664359 0.90602397 1.03055466\n", + " 0.87489391 1.08895224 1.03727143 1.12762453 0.63857225 0.66155415\n", + " 0.97221054 0.71956446 0.75967009 0.86888564 0.90443239 1.0694059\n", + " 0.87587347 0.90670481 0.90588247 1.04795408 0.93420838 1.04887284\n", + " 0.95888011 1.06213087 1.2170206 0.80679429 0.95660671 1.00914037\n", + " 0.72573698 0.71583814 0.98074695 0.91274656 1.13978346 1.00785996\n", + " 0.84066635 0.85408688 0.98270181 0.87417911 0.97970217 0.8135024\n", + " 0.96901914 0.96800944 1.10420551 1.00441832 0.88336196 0.84259626\n", + " 1.02103809 0.9867404 0.83924652 0.9282772 1.01569183 0.99045284\n", + " 0.86532125 1.07132457 1.11916042 0.92409006 0.7869966 0.97967815\n", + " 0.60227139 1.13119105 1.17068637 0.83197875 0.83291981 1.07752283\n", + " 1.14591205 1.10275467 1.11604747 1.17261929 0.81830111 0.7341991\n", + " 1.14899489 1.00894662 0.78401169 0.94329404 0.98301021 0.85541349\n", + " 0.93422613 0.92167027 0.81380916 1.04419489 0.93667762 0.88094109\n", + " 0.71034521 1.01978941 1.01477568 0.92116888 0.95290002 0.74605114\n", + " 0.99900057 0.95165538 0.87291955 0.79672869 0.78111824 0.81800149\n", + " 0.81958085 0.70492237 0.65028099 0.68315842 0.62790367 0.84643214\n", + " 0.82799433 0.63289467 0.83760637 0.84406011 0.62671952 0.73126021\n", + " 0.91210069 0.77836218 1.17361277 1.05446476 1.17624901 0.34612718\n", + " 0.81701362 0.67759816 0.62809201 0.28863132 0.67678309 0.63434821\n", + " 0.62324841 1.21769907 0.98682902 1.19200534 1.14025451 1.09499516\n", + " 1.10267349 1.09841592 1.04738598 1.01494056 1.07195474 0.78843476\n", + " 0.94945012 1.03111514 0.72727668 1.1561826 0.99818285 0.95194042\n", + " 1.09277246 0.86474025 0.98911328 0.84479153 1.04824791 0.94429402\n", + " 0.67354386 0.72554871 1.03012611 1.04437591 1.01156754 1.03233104\n", + " 1.06340766 0.79064531 0.96804192 0.88084698 0.91620912 0.99090477\n", + " 0.60439413 0.97364667]\n", + "Distances (cosine): [0.9640993 0.79699994 1.09986502 0.84237682 0.84863022 0.93837033\n", + " 1.07841196 1.02805957 0.69520493 0.97629205 0.90331336 0.99732104\n", + " 0.96492661 1.11886996 0.75796474 1.09612358 0.68740512 0.7584465\n", + " 0.34887749 0.44535615 0.64352897 0.62966815 0.23350003 0.30958678\n", + " 0.94908845 1.15184299 1.10352169 1.23195209 1.14882867 1.09639136\n", + " 1.13692662 0.76488881 0.92817093 1.03795404 0.97331036 1.15739918\n", + " 1.22457966 0.95253103 0.94298229 0.90288162 0.85286628 1.04495653\n", + " 0.80403952 1.10766102 0.94633592 1.19325061 1.10003179 1.13188064\n", + " 1.08753891 1.20071959 0.37292459 1.09508229 0.33690319 0.72906508\n", + " 0.78767758 0.98321252 1.11290476 1.0548636 1.05271729 1.07018568\n", + " 1.1633898 1.29527216 1.11920955 1.10961616 1.19010542 1.00566022\n", + " 0.99471763 0.73975335 0.63713328 1.0880376 1.10704951 1.02651322\n", + " 0.99297676 1.18502407 1.03377546 1.02001939 1.07396828 0.92303849\n", + " 0.94784728 0.88795639 0.94458516 0.75313719 1.0858257 0.85260693\n", + " 0.90548389 0.98460732 1.04576865 0.80823235 0.87124624 1.0509202\n", + " 0.99189713 0.83857197 0.89124998 1.10615267 1.09193806 1.06307056\n", + " 1.04722817 1.04819679 0.70297256 1.084382 0.84727173 0.82036039\n", + " 1.0337954 1.01200552 1.16488638 0.88649608 0.91055832 1.12887916\n", + " 0.57079833 1.05737377 0.75267376 1.06887253 1.16029955 0.67905778\n", + " 0.46825468 0.9157126 0.42191851 1.03705668 1.02243457 1.17912015\n", + " 1.23426381 1.01052644 0.81240271 0.95498956 0.99096624 0.85801257\n", + " 0.97214744 0.96583189 1.17991593 1.10431824 1.05618854 1.08910781\n", + " 1.02159446 1.12260079 1.07865804 1.09036334 1.22520778 0.71964885\n", + " 0.8750669 0.98034175 1.01458896 1.202222 0.93936417 1.03569487\n", + " 1.12396458 1.09177669 0.76199239 1.06239105 0.89514679 1.05428316\n", + " 1.05698992 1.0199024 1.07435772 1.14019548 1.08265623 0.97801383\n", + " 0.96752076 0.93965086 1.03564324 1.00605766 1.03696195 0.97583326\n", + " 0.97335048 0.60813266 0.89208176 0.944989 1.07530572 0.83897213\n", + " 1.14577609 0.96248398 0.94913484 0.85172507 0.71530978 0.95444484\n", + " 1.02891525 0.90347319 1.05056097 0.85354203 1.09431545 0.77921213\n", + " 0.86364651 0.93009692 0.69878816 0.87577969 0.6576698 1.0650245\n", + " 1.2559693 0.92221451 0.83708187 0.91825058 0.95049304 0.90203442\n", + " 0.98929249 1.01642476 0.88054962 0.96162952 1.06976663 0.91925555\n", + " 0.89573795 0.81570876 0.63585618 0.42818188 0.71096397 0.7633811\n", + " 0.23628287 0.33633961 0.96959382 1.17431892 1.05050824 1.01096852\n", + " 1.06813021 1.02451246 0.87753014 0.97595722 1.19693314 0.80172812\n", + " 0.90166816 0.89356936 0.86327427 0.98003599 0.90030543 1.03032\n", + " 0.99233638 0.92171781 1.0104735 1.02963288 1.15656196 1.07644942\n", + " 0.98363459 1.0491147 0.8407148 1.06748866 0.34870545 1.17381653\n", + " 0.87717743 1.01919614 0.68826273 1.29322726 1.27832372 1.28541115\n", + " 1.19436095 0.3576905 1.04427175 0.81747915 1.08656433 1.12511809\n", + " 0.96842095 1.14545219 0.95497139 0.74183274 0.83482312 1.06216532\n", + " 0.77723301 1.02151839 1.02799237 1.0244516 0.9772488 1.17553896\n", + " 0.9053147 1.21626279 1.21858605 0.71251691 0.84843965 1.05079004\n", + " 1.09386599 0.95550006 0.85665361 1.12551201 1.12396114 1.09933953\n", + " 0.70139866 1.05643536 1.21422624 0.89690958 1.07005488 1.04275651\n", + " 0.81334154 0.92944535 0.86535959 0.5304813 0.77489586 1.05440964\n", + " 1.04132413 1.18294092 0.92936784 1.09856545 0.93011821 0.994987\n", + " 0.99293771 1.01832635 1.0323814 1.03651737 0.8162463 1.03445635\n", + " 1.0393354 0.96332485 0.8802862 0.89416538 0.88921979 0.84756707\n", + " 0.78235454 1.21479542 0.99747125 0.83240989 0.89295588 1.11347277\n", + " 0.72021878 0.92478823 0.73228249 0.27720932 0.8549848 1.04681009\n", + " 0.88847747 0.79264941 0.81604479 0.85317487 0.57857088 1.09034429\n", + " 1.03324891 1.00293259 0.49073483 1.02732309 0.99081297 0.96343451\n", + " 0.96242482 0.92416716 0.79107065 0.92786569 0.9245141 0.92647353\n", + " 0.7839101 0.91757127 0.86634149 0.84181649 0.96414228 0.74094544\n", + " 0.97267163 1.11905111 0.89687418 1.17734929 1.082337 0.80906485\n", + " 0.87124504 0.96182753 0.84841982 0.86389783 0.89584251 0.85475054\n", + " 0.9993762 0.96787098 0.95975712 0.89336805 0.87099456 0.95606513\n", + " 0.70608644 0.91101126 0.94630152 1.04581005 0.35622075 0.96273664\n", + " 0.74447761 0.73348279 1.06314809 0.96768244 0.88580677 0.92799334\n", + " 0.83054254 0.83837722 0.97873592 1.06848373 0.62536938 0.84208893\n", + " 0.99473204 0.90404592 1.0286489 1.03058003 0.93724164 0.91358049\n", + " 1.09374484 0.87907219 1.01416603 0.7857285 0.97385777 0.76574927\n", + " 0.89758594 0.89429332 0.83086945 0.89082861 0.71391764 0.98994632\n", + " 1.15336246 0.86700479 0.79451002 1.00507003 1.08453869 0.77503003\n", + " 0.99681163 1.02318083 0.93513651 0.98474194 1.11328412 1.06592778\n", + " 0.8202716 1.08997623 1.04944714 0.85613897 0.72320502 1.02313871\n", + " 0.89752921 0.70365912 1.01391808 0.99938188 1.02504636 1.11781768\n", + " 0.92621503 0.90039325 0.909878 0.63369778 0.98562951 0.80162692\n", + " 0.92099258 1.17710141 1.13750494 1.00285106 1.0756449 0.93328874\n", + " 0.99396461 0.95127048 0.92189007 1.02876974 1.03610349 0.91473701\n", + " 0.92835777 0.91267457 0.71710206 1.13870882 1.11193386 1.11839091\n", + " 1.21451225 1.04275482 0.81247145 0.96262034 1.21395455 1.26878367\n", + " 0.97418671 1.062595 0.99820081 0.89072411 1.11190141 0.91461111\n", + " 1.26343646 1.10436252 0.97953956 1.01693443 0.85258903 0.98794351\n", + " 1.13485159 0.89906035 0.94800102 0.95300161 0.92048665 0.90974068\n", + " 0.78440614 0.68553956 1.00860055 1.06461087 0.99009641 1.02069526\n", + " 0.94848482 0.93305782 1.0160739 0.95378741 1.03891594 1.07107594\n", + " 0.95954109 1.04979115 0.88626582 0.81950732 0.91569664 0.91022483\n", + " 1.05428021 0.73438711 1.00966479 0.86919406 0.78073844 0.87081939\n", + " 0.86333941 0.77837867 0.77680106 0.73603365 0.76148676 0.96805507\n", + " 1.1711913 1.13495742 1.12996091 1.23133273 0.92199168 1.2644181\n", + " 1.28730885 1.16867763 0.85377384 0.94842568 1.12345744 0.94942429\n", + " 0.94874334 0.83464591 0.96142326 1.06801144 0.91741855 1.12269446\n", + " 0.960189 0.79924978 0.91201278 0.77009228 0.92138468 1.00942213\n", + " 0.81055642 0.81136672 0.89385485 1.00787732 1.20463405 0.96991912\n", + " 1.03020148 1.02693635 1.12062703 0.99159575 0.96353349 1.18204009\n", + " 1.08260574 1.14901338 1.20625337 1.0722351 0.86871404 0.70398938\n", + " 0.65695904 1.12824584 0.910812 1.14592796 1.20287737 1.00705008\n", + " 1.00627192 1.12926463 0.90434841 0.70577964 1.08313163 1.04051603\n", + " 0.92663498 0.90243345 0.61046286 0.99511666 0.92499561 0.92649286\n", + " 0.98553772 0.96679946 0.9958036 0.97338856 0.80602442 0.92819\n", + " 0.97611385 0.75887914 0.78937502 0.97336985 0.91134288 1.05322354\n", + " 1.0218551 1.07854823 0.80382818 1.13486529 1.07819458 0.96523802\n", + " 0.9048751 0.98399547 0.96316543 0.97669869 0.74715758 0.79513391\n", + " 0.81415386 1.04312258 0.83303872 0.91564231 0.76986244 0.96587564\n", + " 0.81041811 0.98550269 0.88319786 1.16827758 0.73850472 0.74403601\n", + " 1.05718927 0.88414818 0.73391478 0.8438455 0.84416384 1.07346636\n", + " 0.90440824 0.9727104 1.00622954 0.99081652 0.80908583 0.83936706\n", + " 1.03767102 1.02146814 1.03838392 0.94078895 0.97048102 1.02162025\n", + " 0.64856801 0.68504973 1.00707922 0.98771797 0.91131966 0.9493894\n", + " 0.80177702 0.90394974 1.09360264 0.86900394 0.9006126 0.6995088\n", + " 0.7493072 0.74866107 1.14769184 0.74361704 0.96530201 0.87913855\n", + " 1.02019751 0.88891139 0.89556652 0.89441066 0.97573306 0.92274332\n", + " 0.85920736 1.00772964 1.01175937 0.97171441 0.72014826 0.7695259\n", + " 0.60049885 0.95822193 0.98071364 0.74108661 0.83062638 1.0133477\n", + " 0.98314087 0.93432704 1.16874278 0.99910121 0.99576993 0.71946615\n", + " 1.03072026 0.92775501 0.77934698 0.85503733 0.9107281 0.96024453\n", + " 0.85137667 0.71487427 0.69744085 0.95802644 0.81478367 0.78537957\n", + " 0.62050026 0.84240748 0.9084148 0.88880322 0.90758798 0.8570286\n", + " 0.78055429 0.88930972 0.74096005 0.60059808 0.69333365 0.6608848\n", + " 0.72040725 0.62396579 0.43073537 0.65759007 0.6958151 0.74786208\n", + " 0.76273381 0.62464676 0.80341517 0.79459691 0.52198217 0.68808826\n", + " 0.6772867 0.78064569 1.20129983 1.07989404 1.11822884 0.64806325\n", + " 0.69265845 0.32592226 0.31832404 0.5987124 0.65226267 0.28394492\n", + " 0.31943969 0.93136601 0.93841555 1.04858979 1.03495732 1.01500057\n", + " 0.91079287 0.90597223 0.9635261 0.90323389 1.18402958 1.09913312\n", + " 0.9672969 1.01206062 0.85547377 1.05430686 1.01164409 0.99171344\n", + " 1.21710651 0.77154524 0.93519933 0.80349673 1.06023912 0.77811318\n", + " 0.70774461 0.6843138 0.91070058 1.09019953 0.87468856 1.04214032\n", + " 1.0467724 0.93796523 0.96441884 0.87215196 0.92677263 0.96878135\n", + " 0.67977902 1.09698215]\n", + "Distances (cosine): [0.79908111 0.73927687 1.06708251 0.85273174 0.73477776 0.97931733\n", + " 1.15717008 1.04689102 0.76079206 0.95669637 0.8625687 0.96083231\n", + " 0.93360211 1.16530425 0.80655799 0.95865983 0.84671028 0.87091818\n", + " 0.38244526 0.78497146 0.83519839 0.80662462 0.50979546 0.71074501\n", + " 0.71153826 1.04650101 1.0649136 1.11200005 1.1937854 1.01285918\n", + " 0.97267796 0.88781235 1.11234429 0.98895468 0.85436357 0.88559368\n", + " 0.89954621 0.96007104 0.7897397 0.98097446 0.80211829 0.87353476\n", + " 0.84895218 0.85481954 0.876547 1.12109919 0.97923431 1.09625631\n", + " 1.15711111 1.11522427 0.64456604 1.09841815 0.66604295 0.81208979\n", + " 0.84036416 0.77816837 1.1547357 1.10989079 0.9876886 0.66489987\n", + " 0.86905466 1.07481958 0.94426439 0.81386628 0.92069161 0.98126827\n", + " 0.83084011 0.84017016 1.0572067 0.86548504 0.87353432 0.93402167\n", + " 0.95065681 0.85075874 1.04778706 1.00473324 0.8759625 0.84068109\n", + " 1.02038454 0.79316769 0.90681227 1.12942827 1.00747079 0.93714305\n", + " 0.95206313 1.01678202 1.09657377 1.05726545 0.86026982 0.98790538\n", + " 1.0157762 0.88152324 0.90006525 0.93870305 1.01315261 1.20427408\n", + " 0.85696882 0.9616036 0.70567474 1.11066946 0.91650548 1.04384959\n", + " 1.01096906 1.10939046 1.12584293 0.72615414 0.70119282 0.91918429\n", + " 0.95433439 0.90014563 0.97574681 1.00754574 1.2220121 0.84882906\n", + " 0.55364322 1.01385129 0.62728755 0.99663488 1.06725993 1.04393421\n", + " 1.14147949 1.17752329 0.89359901 0.94216866 1.11553475 1.10094536\n", + " 1.05861669 0.99963173 0.95077919 0.96474281 0.95209713 0.96762571\n", + " 0.84017964 0.94947213 0.97640498 0.85818313 0.91695714 0.74926454\n", + " 1.1055307 0.99550005 0.89494416 0.8502504 1.07676681 0.97099619\n", + " 0.73644759 0.72589955 0.7679438 0.84877673 1.03543086 1.04647861\n", + " 1.11674486 1.05081578 1.13449978 1.06833339 1.10528614 1.07234597\n", + " 0.99815522 0.89495853 0.96159561 0.90249731 1.00699271 1.09662969\n", + " 0.93795777 0.81279839 0.85128067 0.87188531 1.19001346 0.92097311\n", + " 1.14034961 0.99351593 1.00656554 1.01699075 0.98305181 0.94896057\n", + " 0.97632637 1.01067973 0.9091754 0.89769507 1.00432221 1.05588188\n", + " 1.12076591 0.88723504 1.08645919 0.88562836 0.85784169 1.11320863\n", + " 1.06126668 1.01341861 0.96807518 1.08298973 0.99437477 0.93235862\n", + " 1.01337308 0.97605538 0.83756043 0.75838728 0.98120539 0.70363846\n", + " 0.8458801 0.92780311 0.65682844 0.80503096 0.93150785 1.04293512\n", + " 0.68522719 0.82562939 1.11108932 1.11014248 0.75362199 0.97349169\n", + " 1.07496052 1.02851022 0.88174533 1.03125071 1.05449818 0.71758938\n", + " 0.79159791 1.00759128 0.87518147 0.98801904 0.90998367 1.09813142\n", + " 1.03657542 0.95999973 1.00392549 1.08573047 0.99440003 1.03081182\n", + " 0.78812237 1.01927 0.77064493 0.95279206 0.72252125 1.02399697\n", + " 0.74197884 0.97826187 0.89888565 0.99355318 0.96201307 0.96652534\n", + " 0.94184268 0.25396192 0.7493765 0.90807884 0.70809421 0.94178418\n", + " 0.97511678 0.80634451 0.98581152 1.06072993 1.01005566 0.94320242\n", + " 1.02337968 0.64439638 0.64769702 0.60513261 0.7555751 0.94128801\n", + " 0.99187264 0.86386565 1.07299225 0.90880302 0.77923438 0.94077548\n", + " 0.88673337 0.7281395 0.82725276 0.98710909 0.86437454 1.04571151\n", + " 0.79312343 0.96648613 0.96167187 1.09885804 0.77093196 1.16519824\n", + " 0.87990819 0.83667481 0.80933533 1.07361809 0.97240444 0.89642668\n", + " 1.06981224 1.30089778 1.05820417 0.99594716 0.96550001 0.89359601\n", + " 1.05851306 0.91861905 0.90424047 0.99563761 0.66308237 1.0520874\n", + " 0.93400518 1.1609704 0.97295296 0.73532681 0.881064 1.05832384\n", + " 1.05485217 1.0342685 0.88448353 0.9726835 1.05777027 0.93390591\n", + " 0.78788859 0.89349423 0.74393231 0.53463579 0.69697003 0.95201781\n", + " 0.76087283 0.71435445 0.78956002 0.40986545 0.55243629 0.81466177\n", + " 0.95964474 0.87679209 0.51171364 0.96375923 1.00546129 1.00787475\n", + " 0.81722586 0.88161951 1.06886271 0.7655628 1.09495965 1.05379447\n", + " 0.99277356 1.00476895 0.88036287 0.88438476 0.86537457 0.8261744\n", + " 0.9446573 0.73611498 0.88303315 0.97983821 0.92940804 0.91261826\n", + " 0.83367175 0.98961829 0.95246502 0.96717629 0.92708615 1.05043092\n", + " 1.01433278 1.1678357 0.9636643 1.11426713 0.77385638 0.70012296\n", + " 0.75033189 0.82984885 0.93324737 1.04789456 0.61246075 0.88989631\n", + " 0.82865582 0.92108745 0.93318505 0.88514942 1.11284032 0.90753186\n", + " 1.05065392 1.09176979 1.11070994 1.16162725 0.98366305 1.0839678\n", + " 1.1932071 1.11767584 1.03593003 1.05563643 0.89452448 1.24350825\n", + " 1.1779094 0.71477341 1.03844376 0.8602801 1.10357657 0.96775181\n", + " 1.03087216 0.98334745 1.05016065 0.92747637 0.82638633 1.02746375\n", + " 0.92436155 0.80349123 0.8313303 0.96193335 1.08843484 0.64826834\n", + " 0.99841496 0.83824504 0.8123247 1.01839856 1.15155453 1.04880872\n", + " 1.01510452 1.07802569 1.14784751 0.99891638 1.09521153 1.11986649\n", + " 1.06713559 1.05363791 0.90810599 0.83434853 0.8107911 0.94172835\n", + " 0.9896609 0.9982981 0.95329301 0.91994077 0.99442741 0.96535035\n", + " 1.03421622 1.13986887 1.06472476 0.99306289 0.95366658 1.00997007\n", + " 0.9306631 1.01658451 1.09833789 1.1099149 0.99630483 0.86665176\n", + " 0.95058076 0.90166695 0.99837408 1.12124232 1.0524317 1.0464936\n", + " 1.06885405 1.02390015 0.94150143 0.92480506 1.07705303 1.077649\n", + " 0.92056932 0.92294082 0.99023854 0.95974531 1.10811909 0.96900426\n", + " 1.17729322 1.16700669 0.99470372 1.07160378 0.9825647 1.14979498\n", + " 1.27901756 1.04627501 1.12532388 1.01628432 1.03325062 1.16245798\n", + " 0.87847854 0.67649062 0.80839075 0.90618508 0.95748419 1.043942\n", + " 0.90106258 1.03349252 1.05486578 1.03720413 1.22440163 1.20915921\n", + " 0.91748325 1.01570589 0.91055753 1.06042773 0.82935107 0.83913135\n", + " 1.23908915 1.19224025 1.08792936 1.04037044 0.94311693 1.11121802\n", + " 1.00663387 0.84066813 0.9767006 0.86707671 0.97022408 0.99814927\n", + " 1.1442741 1.1654167 1.14562428 1.19097204 1.13578646 1.06334554\n", + " 1.0539729 1.00987822 0.82205625 0.87411286 0.92038039 1.01775004\n", + " 1.14994666 0.85396471 0.88434408 0.86745271 0.69687756 0.82026731\n", + " 1.0061832 1.06818965 1.08715668 0.83905553 1.00894969 1.03320296\n", + " 1.08996961 0.95516688 1.09027852 0.98481366 1.0692466 0.96337249\n", + " 0.77946137 1.15973017 1.12933446 1.18223796 1.06838696 1.16474659\n", + " 0.96523368 1.11094058 1.01445395 1.08538164 0.99719707 0.96837924\n", + " 1.00128105 1.21262294 0.77064615 1.17904666 1.29573023 0.94712684\n", + " 0.82827903 1.05534424 0.9948306 1.013226 1.06905636 0.93703991\n", + " 0.86041109 0.83724391 0.77395207 0.94721436 0.84805494 1.10094822\n", + " 0.89321219 1.01387545 1.02919957 1.05987136 0.89225483 1.00097486\n", + " 0.81888215 0.72551672 0.73611302 1.04437912 0.78607208 1.09475747\n", + " 0.97278861 1.07010782 0.99593159 1.0776409 1.16859478 0.96724973\n", + " 1.00400609 0.86766442 0.91879166 0.80014409 0.56049269 0.89961012\n", + " 0.85374424 0.80829507 0.82122676 1.0412673 0.80163904 0.67119885\n", + " 0.74820923 0.97707253 0.94478569 1.23434246 0.82572273 0.83816877\n", + " 0.80762537 0.87149442 0.82878897 1.0502462 0.9338512 0.99865436\n", + " 0.81923173 0.86731322 1.01531664 0.92746816 0.76621142 0.83689479\n", + " 0.8880825 1.03743199 1.07728455 0.8208952 0.98571323 1.00834672\n", + " 0.84867814 0.87063664 0.93794591 1.05451811 1.00579318 1.09513149\n", + " 1.03803631 0.93268498 1.30015033 1.07625263 0.89674032 0.87912433\n", + " 0.95189704 0.93805672 0.85864878 0.89673796 1.03297067 1.01670426\n", + " 0.97782869 0.9380319 1.10612258 0.90162563 1.16067494 1.1752781\n", + " 1.07374732 0.94531409 0.95593172 1.12653551 1.02273242 1.04571896\n", + " 0.6744976 0.88407937 0.98044862 1.04812163 0.93460592 0.97151996\n", + " 1.01862611 1.07114171 0.95642514 0.99544281 1.0239257 0.79447079\n", + " 1.04269873 1.07041066 1.00010442 0.90836743 0.89402054 0.94082642\n", + " 1.02966379 1.11548084 1.12162987 1.10051727 1.00345376 1.19852842\n", + " 1.04201465 1.01524578 1.0380211 1.1022665 0.96908443 1.03732815\n", + " 0.88183242 0.9042574 0.88305126 0.86813785 0.81322214 0.91198201\n", + " 0.82329748 0.58399836 0.67344312 0.9363441 0.9325137 0.73910824\n", + " 0.89819286 0.74077595 0.91707532 1.03875401 0.84873276 0.8655165\n", + " 0.78768683 0.78970092 0.95718926 1.00534419 1.04581949 0.82230526\n", + " 0.81955435 0.40488158 0.71774588 0.79811209 0.84710547 0.39699464\n", + " 0.75910707 0.72513821 1.02432389 1.16321629 1.10200362 1.01685563\n", + " 1.08144752 1.1498729 0.97053642 1.08768637 1.0287886 0.91475583\n", + " 0.89617455 1.02875432 0.88411852 0.89554627 1.02719507 0.97801067\n", + " 1.01463273 0.94886902 0.8437611 0.72296983 1.01923928 0.69517018\n", + " 0.65640334 0.92942246 1.1196623 0.9433791 1.08332614 0.83324564\n", + " 0.80490142 0.86333114 0.90904419 0.84543531 0.82554608 1.01255578\n", + " 0.76780056 1.05428984]\n", + "Distances (cosine): [0.527668 0.97500192 0.9221239 1.0757162 1.03432262 0.93281117\n", + " 0.87208268 0.96459169 1.06430908 0.60045559 0.74402294 0.81812041\n", + " 0.80228555 0.81392971 0.87476547 1.12214617 0.82201105 1.15347995\n", + " 0.94100947 1.10614256 0.82773723 1.16635552 1.00933521 1.12378526\n", + " 1.15157763 0.75613414 0.77501764 0.83588164 0.88674814 0.81474205\n", + " 0.78097442 0.89027819 0.98669819 1.12287692 0.78792681 1.13059253\n", + " 1.11677816 1.07971428 0.76449673 0.94627512 0.8416973 0.84479077\n", + " 0.93112701 1.0459214 0.91973465 0.79451399 0.79407811 0.93065084\n", + " 0.99240529 0.92820073 1.07032453 1.05447824 1.0955374 1.02696019\n", + " 1.01017163 0.95274773 0.9741497 0.98636249 0.24423288 0.84716004\n", + " 0.84357769 1.04289925 0.92560831 0.73445319 0.65546604 0.94399193\n", + " 0.99768288 1.05654644 0.92540986 0.91901684 0.85034383 0.80773919\n", + " 0.82382623 0.91348755 0.80537884 0.79689129 0.23881253 0.36648207\n", + " 0.79319947 0.82813141 0.92132681 1.13170765 0.94996224 0.94244032\n", + " 0.92154708 1.05485906 1.10368386 0.91186326 1.12691569 1.01735853\n", + " 0.98811497 0.9619129 1.00464106 1.10968805 0.94338915 1.06478764\n", + " 0.87883601 0.93354648 0.85627692 0.81072169 0.83720037 0.93201277\n", + " 1.13130718 1.13054781 1.17831873 0.83179331 1.2100147 1.00957361\n", + " 1.06376933 0.87839425 1.18798383 1.04568144 1.05886351 0.75055535\n", + " 1.158863 0.99354791 1.16908212 0.97109405 0.90391154 0.8973484\n", + " 0.97874308 0.85746005 0.88539048 0.60060596 0.98715553 1.25157164\n", + " 1.09171028 0.99124393 1.01751139 1.09734313 1.01643929 1.02539739\n", + " 0.88813004 0.9200778 1.118868 0.75233002 0.85342016 1.14184129\n", + " 0.9319245 0.75792237 0.63664436 0.80640746 0.73603447 0.9128514\n", + " 0.83584295 0.75768379 0.81797993 0.8040239 1.00950109 1.03650464\n", + " 0.96002748 0.77813257 1.07725181 0.86093337 1.10947656 1.01829263\n", + " 1.04625223 0.98460623 0.9124533 0.91437285 0.92793642 0.97563272\n", + " 1.04206019 1.10869838 0.97531818 0.99371151 1.0160163 0.9444338\n", + " 1.02313215 1.14709434 1.11628036 1.00568427 1.1177585 0.86852461\n", + " 0.65175003 0.94622119 0.93720079 0.81829976 0.92484313 0.99964736\n", + " 1.13054025 1.07414293 1.00163497 0.84717747 0.92404554 1.03493043\n", + " 0.94631328 1.06581992 0.94129479 0.92925672 0.88939705 0.68414537\n", + " 0.88170044 1.13958318 0.78554811 1.00295135 0.86515663 0.85657185\n", + " 0.94535719 0.78247536 0.85371224 1.10204042 0.84953363 1.2619723\n", + " 1.16169013 1.23220083 1.2237892 0.70050441 0.86248865 0.80836613\n", + " 0.80280108 0.93887806 1.05057002 0.92900718 1.01001261 1.02803824\n", + " 1.14336084 0.91057145 1.07429472 1.12221458 1.04314162 1.02664541\n", + " 0.9630015 0.99032975 1.01938347 0.95933765 0.91714068 1.11928176\n", + " 1.0347135 1.10169671 0.85972813 1.22298729 0.89509502 0.82750944\n", + " 0.65438216 0.94339688 0.97353717 0.66366348 0.64940178 0.83075974\n", + " 0.84800571 0.93198626 0.98296825 0.98234245 0.8628637 1.04658244\n", + " 0.91177141 1.06205416 1.0376464 1.04534721 0.99655727 0.94749908\n", + " 1.13749993 0.83182531 0.78464403 0.83595007 0.66520003 0.72671027\n", + " 1.06572607 0.96488601 0.75750512 0.9464862 0.94625877 0.94022671\n", + " 0.75413182 0.93029524 1.07112501 0.94041683 0.95456033 0.908184\n", + " 0.78575092 0.61478227 0.93209352 0.94064366 0.74835687 1.17714918\n", + " 0.82171249 0.89515892 0.80345739 1.07301501 0.90164563 1.0029371\n", + " 0.93882705 1.01212971 0.85823762 0.8334244 0.88196567 0.68399081\n", + " 0.94218102 0.87978592 0.90928344 1.16844924 1.0285414 1.02975426\n", + " 0.6373895 1.02835093 0.9132429 0.87748187 0.65240379 1.04997231\n", + " 1.00045094 1.11016766 1.00036471 1.09632258 0.98268494 0.67559427\n", + " 0.89407903 0.89278319 0.77971862 1.01092694 0.99482725 0.64824678\n", + " 0.39108287 0.93661521 1.07704279 0.88147622 1.18985815 1.06168893\n", + " 1.09790311 0.99315826 1.13584177 1.08963182 1.08653879 0.85027319\n", + " 1.16951034 0.84452895 1.02495224 0.70125196 0.87265605 0.78092524\n", + " 1.09277101 1.10886379 1.08379497 1.1762102 1.00671745 1.11979782\n", + " 1.00719447 0.89803566 1.00674339 0.95945929 1.0869182 0.70890198\n", + " 0.49417604 1.1597765 1.00667041 1.19329792 1.11763833 1.18866021\n", + " 1.17973783 1.19555964 1.18437664 1.09509961 0.78053227 0.92793041\n", + " 0.80805189 0.90609271 0.80871937 0.81387176 0.87645194 0.94575138\n", + " 1.06280063 0.9237728 0.87904094 0.75646923 0.94950148 0.79179003\n", + " 0.921351 0.88697256 0.75837177 0.68752281 0.81830838 0.94834889\n", + " 1.01726888 1.05439905 0.77235683 0.64060574 0.81308774 0.83586086\n", + " 0.78777647 0.96176595 1.24999283 0.80623133 0.78821169 1.07207937\n", + " 1.04848094 0.94761505 1.16516808 1.04534866 0.86968022 1.01969437\n", + " 0.78820407 0.88957681 0.9078708 0.94538919 0.795858 0.84059317\n", + " 1.11138591 0.89762764 0.84728868 0.58213273 1.09148103 0.87881526\n", + " 1.02892534 0.9232085 0.96380114 1.00693236 1.07318101 1.01806428\n", + " 1.13383549 0.99208417 1.06356413 0.99885986 0.8500064 0.95693527\n", + " 0.95830657 0.84698526 1.16554991 0.83844606 1.11203553 0.9253493\n", + " 0.95917024 0.90634881 0.938603 0.97452211 0.92406073 0.89765085\n", + " 0.98721005 1.09976387 1.015735 0.94977453 0.93465233 0.96670367\n", + " 1.01028356 0.98176289 1.14373027 0.86189213 0.85927942 0.89038611\n", + " 1.02735687 0.97803611 1.10832584 0.95221745 0.66881122 0.83537206\n", + " 0.81301185 0.63197911 0.69169903 0.83918746 0.8332434 0.63523671\n", + " 0.54671599 0.79837726 0.88177646 0.49072436 0.71310541 0.69522046\n", + " 0.75888488 1.01260704 1.16665019 1.22222713 1.11121528 1.02556801\n", + " 0.89283407 1.01992478 0.79394733 1.02136929 0.80818398 0.61451901\n", + " 1.04600226 0.74922425 1.01235614 0.89413899 0.94146684 0.92619254\n", + " 0.99059648 1.11579634 0.8315289 1.04268825 1.00119595 0.85294985\n", + " 0.97375476 1.18536993 1.18990416 1.0931943 0.95641917 1.17323944\n", + " 1.11385244 0.95139128 0.9490408 0.86565905 0.96262659 0.62050559\n", + " 0.75651191 0.6331299 0.68582775 0.66879802 0.77521981 1.21349821\n", + " 1.18202302 1.03272151 0.76752042 0.77613692 0.91926159 1.03783297\n", + " 0.93159605 0.96293336 1.03486969 0.75293795 0.92773575 0.94976919\n", + " 1.00329425 1.03508725 1.03334527 1.00219884 0.43303534 0.92563522\n", + " 1.03517228 0.98087644 1.00557935 0.69906947 0.77454459 1.02494968\n", + " 0.79179159 1.004452 1.23370558 1.10317989 1.16689457 1.0301278\n", + " 0.65651457 1.07285509 1.12945574 1.02924446 1.02468388 1.07422109\n", + " 0.88841869 1.13060169 1.0004553 0.79808561 0.9283944 0.59210061\n", + " 0.7630709 0.94854616 0.94689589 1.02256407 0.88237134 1.10657103\n", + " 0.86587767 0.84177599 1.13945382 0.93244145 1.09451256 0.9791961\n", + " 0.95409531 1.14442089 0.88729158 0.95784802 1.05605532 1.03473474\n", + " 0.8554417 0.86979217 0.78481785 0.87417889 1.00266003 1.15431645\n", + " 1.00781525 0.90331832 1.09975458 0.97957153 1.02269102 0.93868287\n", + " 1.04864025 0.870557 0.63498252 0.8580946 0.76365282 0.83107483\n", + " 0.94885134 1.07578018 0.93870211 1.08591191 1.15482354 0.75498755\n", + " 0.84016887 1.05939996 1.08279142 1.15916916 0.95953934 0.94818428\n", + " 0.90580089 0.79560999 1.05136111 1.04944898 0.97190086 0.92961428\n", + " 0.84249806 1.02135882 0.52873163 1.02118532 1.15673069 1.13527785\n", + " 1.02815684 1.09657583 1.08750893 0.92996535 1.0669267 1.06913378\n", + " 0.9057668 0.98848634 1.04555462 0.65573272 0.98602089 0.9856081\n", + " 1.0405076 0.91767168 1.11378856 0.9692744 0.97407286 1.1471927\n", + " 1.18898847 1.17142686 0.98051254 1.1187243 0.93696993 0.86447277\n", + " 0.86707951 0.86832143 0.76502552 0.90345131 0.96804011 0.98163398\n", + " 0.90856549 1.0375325 1.05181864 1.05266386 0.91894458 1.18376633\n", + " 0.83578341 1.09915557 1.07309575 0.94714346 1.11322046 0.98448226\n", + " 1.0299267 1.13639914 0.78668402 0.9719288 0.83813494 1.05326653\n", + " 1.12545139 1.03362844 1.03854837 1.00566168 0.97947914 0.94707057\n", + " 0.9647924 1.07120396 1.04820804 1.05782727 0.82671223 1.02775636\n", + " 0.96364984 1.04924499 0.92063779 0.94486394 0.6014982 0.83696224\n", + " 1.04980374 0.97355553 0.88644075 1.07804659 0.86024033 1.09564583\n", + " 0.91130036 0.85173334 0.99391237 1.05773131 0.88089678 0.7466161\n", + " 0.72365131 0.9649287 0.92093164 0.88575629 0.95488912 0.84003472\n", + " 0.95452068 0.61097274 0.99338125 1.03197637 1.0654022 0.84056987\n", + " 1.24563624 1.05016085 1.18985677 0.84326256 1.17270301 1.04965592\n", + " 1.22823281 1.29789095 1.09868394 1.12825222 0.98368382 0.95229503\n", + " 1.04881056 1.22327047 0.96232267 0.92500946 0.88184231 0.970676\n", + " 0.85682888 1.05119124 0.83418125 0.8945311 1.00339631 0.87054802\n", + " 0.65611905 0.97136538 1.04105355 1.01066599 0.85180336 1.14012398\n", + " 0.93394725 0.8810388 0.97609159 1.008992 0.99329879 0.99068841\n", + " 0.83648675 0.76043206 0.70559328 0.99031512 1.02453378 1.09644361\n", + " 1.00133627 0.86336839]\n", + "Distances (cosine): [0.81137089 0.9170987 0.97821887 0.96367252 1.01680849 1.0233152\n", + " 0.98524957 0.78464137 0.97328636 0.31307621 0.4301419 0.3885285\n", + " 0.35235122 0.74573222 0.95892806 1.11088256 0.97015814 1.14888065\n", + " 1.09967901 1.15842434 0.98561697 1.19448504 1.12446674 1.17669561\n", + " 1.07828485 0.8075318 0.84279061 0.92910738 0.9536258 0.81608865\n", + " 0.97015466 1.14021993 0.87512973 1.1771193 0.92116842 0.99452579\n", + " 0.94608461 1.11860235 0.70617574 1.03177076 0.93384651 1.00950711\n", + " 1.09819878 0.89724497 1.17351282 0.89438755 0.81131608 1.01680947\n", + " 1.08703477 0.92250026 1.11610599 1.05429039 1.12711796 0.958104\n", + " 1.22454533 1.05641883 0.88388853 1.01706471 0.69942414 0.69078233\n", + " 0.766334 0.85529651 1.14952619 0.90889071 0.78993064 0.93911353\n", + " 1.15272658 1.14915472 0.99661799 0.99226073 1.15697753 1.05260582\n", + " 1.04550221 1.05255793 0.89125088 0.93132845 0.70071068 0.6672572\n", + " 1.05131823 0.98937422 0.98100351 1.14516423 0.75152254 1.03753454\n", + " 1.12296409 0.76521322 0.84347732 0.8435878 1.05396609 1.03973618\n", + " 0.94364139 1.07026718 0.93318802 1.03210465 1.01586578 1.07216464\n", + " 1.05936344 0.95223192 0.80897994 1.06289684 1.04123568 1.18535601\n", + " 1.30983049 1.22412822 0.96828463 0.97618403 1.26069176 0.94598623\n", + " 1.08463874 0.99208842 1.22866599 1.2073261 0.97318618 0.84518007\n", + " 1.26764429 1.01247358 1.2778888 1.08479674 0.92766857 0.59299893\n", + " 0.73587757 0.99015511 1.08624506 0.91767606 0.86983326 1.21823807\n", + " 1.14390843 1.2548376 1.06724908 1.16518135 1.10555795 1.12903852\n", + " 0.99850703 1.13034879 1.15573706 0.80721121 0.82479113 1.25880454\n", + " 1.02887877 0.78907209 0.7681334 0.59341205 1.12356989 0.98048461\n", + " 0.98819685 0.90222507 0.98454449 0.92425565 0.98088383 0.80971405\n", + " 0.91298964 0.45273423 1.06406822 0.98164068 1.06112433 0.68224257\n", + " 0.92801991 0.9193082 0.85477962 0.87631294 0.8250427 0.63293993\n", + " 0.91280961 1.17545748 0.82712539 0.84771877 0.87386614 0.67047617\n", + " 1.02999884 1.05921665 0.98296949 0.94028625 1.00511757 0.89462585\n", + " 0.55373795 0.94837431 0.8710255 0.95115628 0.7337239 1.08780094\n", + " 1.14359051 1.23806609 1.00190729 0.97385188 1.0730556 0.89756427\n", + " 0.85096807 1.07086088 1.12836973 1.12367283 1.05144027 0.76652131\n", + " 0.87208718 1.10760973 0.78495624 0.96730334 1.00174789 0.88970335\n", + " 0.94778956 0.91588308 0.96699587 1.20452235 1.00222498 1.23773243\n", + " 1.15803013 1.25883086 1.14352479 0.59390593 0.96877777 0.72510628\n", + " 0.87576574 1.0556084 1.09724327 0.96571236 0.84864651 1.10162055\n", + " 1.04762332 1.0657229 1.16637487 1.17924745 1.10094606 0.9480854\n", + " 0.89088242 0.79736439 0.97436745 0.90714617 0.90539542 1.13843972\n", + " 1.22573705 1.22580095 1.00432982 1.367025 1.00567401 0.92735449\n", + " 0.87200522 0.75703985 1.14809137 0.50748863 0.46243719 0.86292505\n", + " 0.96011282 1.11114418 0.9607496 1.14355595 0.97312932 0.87262018\n", + " 1.02922907 1.16680197 0.83590489 1.05991792 0.84156576 0.90508994\n", + " 0.90172254 0.83283904 0.7903782 0.87156489 0.71682877 1.02568104\n", + " 0.97970458 0.96679515 0.8438116 1.09870007 1.18712692 0.98466167\n", + " 0.91866497 0.92213288 1.10935543 0.95943756 0.9472328 1.09162671\n", + " 0.96565299 0.52785266 0.90747449 0.94963257 0.70629235 1.07803232\n", + " 0.93449084 0.97481931 0.99406377 1.12720122 0.96702658 0.91967305\n", + " 1.01608316 0.98011863 0.99297031 0.85978246 0.70499871 0.81447142\n", + " 0.93154899 0.87545117 0.92525732 1.2475697 1.17217653 0.94111537\n", + " 0.8438113 0.98113367 0.93604129 0.86632207 0.94976961 1.078218\n", + " 1.14300469 0.91423329 1.1662529 0.90558297 0.76645815 0.41901488\n", + " 0.98688987 1.01785685 0.89330588 1.10083629 0.9532572 0.8728929\n", + " 0.76509692 0.97984521 1.14032072 1.02821758 1.19404209 1.02478253\n", + " 1.06139424 0.90506838 1.08627586 0.89836459 1.11576919 1.03913492\n", + " 1.11682241 1.03128174 0.93613082 0.93603049 0.90845903 0.92011513\n", + " 1.18298048 1.12528382 1.04227767 1.19749876 1.02386075 1.09179405\n", + " 1.13602114 1.06378584 1.1017933 1.19091374 1.14413541 0.97406803\n", + " 0.81114148 1.12247222 1.04945662 1.1899848 0.98676867 1.13043231\n", + " 1.16707136 1.18057469 1.18221 1.09439547 0.75036956 1.02312851\n", + " 1.04759372 1.07973118 0.90292492 0.7986211 1.0118339 0.78843886\n", + " 0.96219322 0.99537658 0.8108526 0.66506076 0.96843235 0.97415036\n", + " 0.9077366 1.02202327 0.58395516 0.90177236 0.91886263 0.8650244\n", + " 0.9242622 1.0092439 0.92499671 0.77926408 0.9475931 1.00445874\n", + " 0.83722301 1.1022762 1.13819027 0.8422212 1.0331059 1.16710131\n", + " 1.09731951 0.99830867 1.20579087 1.1593878 1.08851568 1.06758165\n", + " 0.89167155 0.96995244 0.9695067 0.94900704 1.04755863 0.98899173\n", + " 1.02910527 1.06362128 0.90493305 0.88576901 1.13919447 1.0507723\n", + " 1.14054763 1.05154891 1.04740424 1.05657206 1.1620662 1.09386701\n", + " 1.24421394 0.93701143 1.05668102 1.18827134 0.95534258 1.03551698\n", + " 0.88230865 0.79902372 0.99159316 0.94505196 1.08449095 0.9730916\n", + " 0.94293133 0.96699167 1.0478987 0.72533304 1.04079666 0.77976204\n", + " 1.16971542 1.1134519 0.98967753 0.88206468 1.07134635 0.88856444\n", + " 1.00103042 0.92871259 0.95662126 1.039322 1.07533408 1.0378673\n", + " 1.0999767 1.01495376 1.17860466 1.11217907 0.67786548 0.74402836\n", + " 0.81581897 0.79538509 0.8086174 1.09806299 0.77100433 0.88775902\n", + " 0.72884603 0.74254449 1.00665157 0.94368947 0.83806514 0.60415284\n", + " 0.79177901 1.05391747 1.19810321 1.22746114 1.29106552 1.1020938\n", + " 1.06003935 1.1002111 0.866087 0.94733505 0.86598124 0.81411462\n", + " 1.11435716 0.85952399 1.04716797 0.92977197 1.03221085 0.90157278\n", + " 0.76294876 1.02234578 0.87841979 1.12020041 1.03221054 0.85073256\n", + " 1.1318024 1.23102672 1.15866667 1.15072445 0.91379596 1.1417901\n", + " 0.86091625 1.04275792 0.97556191 1.01690508 1.02880049 0.99473293\n", + " 0.85771273 0.87099647 0.83386394 0.86191246 0.92741925 1.17084685\n", + " 1.10837559 1.0321788 1.0701135 1.03078482 0.90085476 1.14133057\n", + " 1.027101 1.03900872 1.00065386 0.85937115 0.82137945 0.79299646\n", + " 1.11047633 0.92556528 0.95396973 1.23835706 0.86979549 0.97943875\n", + " 1.04850322 1.00850363 0.94734684 0.34289268 0.87512954 0.96793836\n", + " 0.7705492 0.91512028 1.04515056 1.00646299 1.07097449 1.15248007\n", + " 0.84723298 1.02850711 1.06950033 1.02997201 1.03102302 1.13351776\n", + " 0.99897171 1.13772859 1.07789824 0.73225912 0.90344498 1.01061712\n", + " 0.85345946 0.79546187 0.95608252 1.04677043 0.71610479 1.2081863\n", + " 0.99812892 0.93952175 1.10018558 1.11115832 1.31370347 1.00396047\n", + " 1.21909612 1.11324722 1.00937434 1.16608213 1.09665772 1.18468329\n", + " 0.84015125 0.91514931 0.97468804 1.08261984 1.06229271 1.04300733\n", + " 0.9385122 1.08243907 1.20205725 1.12046602 1.11745348 1.09658535\n", + " 1.08956827 0.87015073 0.87050505 0.87466987 0.92403863 0.98160023\n", + " 1.06300596 1.19887513 0.90771102 0.92246434 1.2778488 0.86490677\n", + " 0.90149785 1.13981752 1.1121463 0.96765 1.09466127 1.06313166\n", + " 1.09483317 0.93613364 0.98285856 1.23542767 1.09857639 1.09909931\n", + " 1.05060359 1.12206432 0.88360616 1.15057634 1.14197305 1.15446141\n", + " 0.8360253 0.9697701 1.05375926 0.93421966 1.22178733 1.07755654\n", + " 1.05822308 1.10926689 1.04530496 0.9137499 1.16391674 0.89216742\n", + " 1.0146274 0.88511123 1.15128298 0.99530629 1.0302839 1.11059496\n", + " 0.99055413 0.96763708 1.0066738 1.00649344 1.10473032 0.91147842\n", + " 0.98408652 1.04662143 0.74465001 1.13760329 1.11529095 1.10140864\n", + " 1.132316 1.03402027 0.97840534 0.90199806 0.92348265 1.22459057\n", + " 0.89823441 0.9894786 1.0058044 1.12035529 1.22470351 0.6962837\n", + " 0.76944141 1.00305223 0.73447841 1.04628484 0.73915097 1.16281373\n", + " 1.06019991 0.92153789 1.11643337 0.90633336 0.81021858 0.92688479\n", + " 0.93046189 1.04373554 1.13702732 0.9522439 0.8937294 1.0981802\n", + " 0.92635077 0.90392208 0.9739818 1.01105997 0.91538927 0.7883507\n", + " 1.16032403 1.13756608 1.06429554 1.17249203 0.93764848 1.05250303\n", + " 1.12938989 0.91609784 1.09994336 1.19785524 1.06165344 0.96646597\n", + " 1.03735781 0.8557316 1.11429889 0.94725626 1.05901707 1.01443021\n", + " 1.02273789 0.88612624 1.02746649 0.94720004 1.05625989 0.9880061\n", + " 1.20328657 1.141993 1.19011106 0.98389462 1.20155924 1.17739047\n", + " 1.26674988 1.18459612 1.15598195 1.24770696 0.7519667 1.19287855\n", + " 1.13260834 1.16943032 1.10154898 1.02113889 0.88087312 1.02944889\n", + " 0.91487456 0.99241434 0.85397911 1.09268407 0.83381482 0.73087042\n", + " 0.2993128 0.94295102 0.93553927 1.04422846 0.95610232 1.16568228\n", + " 0.91802194 0.98736234 1.04197958 0.96022918 1.04592607 1.12926241\n", + " 0.79652617 0.68971518 0.60874421 0.95329843 0.90598396 0.79384753\n", + " 1.06659486 0.95061722]\n", + "Distances (cosine): [0.83982219 0.84785102 0.90776011 1.02314805 0.97351944 0.96741566\n", + " 1.0276395 0.89625561 0.97140536 0.9680626 0.87461767 0.91070084\n", + " 0.85571179 0.87726713 0.97031846 0.95075474 0.82638339 0.81093675\n", + " 0.91729064 1.15065701 0.78785947 0.7760126 0.89931346 1.05650537\n", + " 0.829198 0.92791663 0.93113358 0.88057683 0.7884134 0.86230079\n", + " 0.7488387 0.96835127 1.03240584 0.89165565 0.85594543 0.9663714\n", + " 0.92936082 0.87384386 0.95153604 1.14959772 0.92169362 0.81786561\n", + " 0.94864521 0.90101922 0.97625422 0.87099712 0.78814978 0.87961081\n", + " 0.83725266 0.83648681 0.98248919 0.87454905 0.94699392 0.95577508\n", + " 1.03973307 1.06600922 0.83958304 0.88198893 0.9518607 0.90186598\n", + " 0.91285739 0.85497226 0.93937096 0.77496703 0.75733635 0.8661877\n", + " 0.92229698 0.82407183 1.21382444 0.78398638 0.88237627 0.97814677\n", + " 0.81653622 0.9484589 0.89482532 0.8843362 0.87922186 0.9002086\n", + " 0.78705286 0.93409233 0.99388718 1.0680285 0.91095664 1.03025111\n", + " 0.78580813 0.8436553 0.93305259 1.03887799 0.97903286 0.9430605\n", + " 0.91649236 0.88852978 0.91824002 0.75891342 0.8015122 0.87619064\n", + " 0.73523862 0.86456445 0.7624684 0.94000566 0.94033632 1.06313686\n", + " 0.96208168 0.92663336 1.14299293 1.02748696 0.91412587 0.8995744\n", + " 0.92206998 0.93240692 1.21035331 0.87219708 0.88062903 0.92679163\n", + " 1.11864855 0.96968483 1.00982425 1.01913841 0.96835847 0.98072824\n", + " 0.94784449 0.94313874 0.79626409 0.95921722 0.93729631 0.92383629\n", + " 0.87459493 0.92591119 0.82077909 0.81849373 0.86869846 0.84089939\n", + " 0.96522306 0.84327203 0.94066242 0.64181256 0.73187248 0.88266535\n", + " 1.13182673 0.9305205 0.82597666 0.7585566 1.07579213 0.85695367\n", + " 0.94959537 0.80932276 1.03325591 0.82823273 1.02415805 0.93829861\n", + " 1.06584009 0.92467575 0.98697582 0.92369635 0.99423894 1.06658031\n", + " 1.12431665 0.8791592 0.93126662 0.95649215 0.98616254 1.15970283\n", + " 0.95110275 0.95486327 1.02529751 1.02537272 0.99123403 0.96104428\n", + " 1.08004035 0.96372254 1.02796605 1.16202925 1.10931924 1.03950115\n", + " 0.67444796 1.04117878 0.9253668 1.12238924 0.91287551 1.09943736\n", + " 0.9397423 1.07233221 1.13432055 0.8971677 0.98697484 0.94866979\n", + " 1.19841829 1.1163729 1.1752368 1.19714159 1.09021128 0.99427685\n", + " 0.87303316 1.06247523 0.72268648 0.87575965 0.81329992 0.84926394\n", + " 0.823151 0.79669145 0.86026759 1.06873049 0.9908547 0.896792\n", + " 1.09652113 1.15642432 1.04563371 1.17190212 1.0430178 1.04038442\n", + " 0.97872475 0.42179418 1.0763532 0.85951825 0.88685591 0.9304495\n", + " 1.07086197 1.17538819 1.00500645 1.10846284 1.07319705 0.98385834\n", + " 1.10666766 0.92636653 0.75920756 0.74586954 0.92987697 1.13174534\n", + " 1.02848161 1.0589783 1.0494612 1.00315614 1.0899506 0.68315579\n", + " 0.71132201 0.91063833 0.97714155 0.99743367 1.00814262 0.91182988\n", + " 0.90650283 0.92784015 0.8943184 0.96523166 0.99842732 0.93602733\n", + " 1.05809203 0.84680145 0.8361474 1.05189417 0.90319348 0.87576888\n", + " 1.08584903 0.97451356 0.9542597 0.96047801 1.07603222 0.89307278\n", + " 0.98118101 0.98239469 0.72978935 1.12874184 0.85426922 0.91951615\n", + " 0.94991815 0.86971732 1.05665631 1.0161311 0.9456956 0.96549672\n", + " 1.06706535 0.93292058 1.06175235 1.08963296 0.77549469 1.17910843\n", + " 0.89518773 0.7727377 0.84058263 1.08645045 1.04201252 1.11227056\n", + " 1.07271693 0.97848387 1.06948628 0.98352737 1.09474525 0.85722132\n", + " 0.82955252 0.89932279 0.92746862 0.94601251 1.05550788 0.81629678\n", + " 0.95141732 1.0044965 0.94777282 0.97452741 1.00931873 1.04310104\n", + " 1.1027806 0.8064357 0.96322069 1.01615433 0.94639179 0.85594334\n", + " 0.81685723 0.94120645 0.92537809 0.9273052 1.04502357 0.94628854\n", + " 1.02062871 0.96469043 0.96802887 0.82090063 0.95881449 1.03719752\n", + " 0.92051657 0.96351419 1.00267028 0.97170391 0.84480476 0.97389411\n", + " 0.86063151 1.07647178 1.04622677 0.8251521 1.08886852 1.11313586\n", + " 1.21629142 1.07772684 0.95607897 1.05896914 0.86033253 1.02620132\n", + " 0.93869738 0.8912867 1.07543381 0.86156398 0.99267743 1.04211705\n", + " 1.05557462 1.03482199 1.12549084 1.06585417 1.06006664 1.07173559\n", + " 1.05398277 1.0921622 1.09462826 1.09734843 0.99044405 0.88777541\n", + " 0.99965784 0.94439868 0.82043424 0.8067286 0.91389158 0.89179502\n", + " 0.92156254 0.96583612 0.9076891 0.92267145 0.98248093 0.9787519\n", + " 0.98730859 0.88439251 0.80828591 0.92289365 0.96251868 1.09972352\n", + " 0.92498168 0.94249131 0.75760173 0.9107805 0.97897482 0.97845514\n", + " 0.94113377 0.90013829 1.16987998 0.99487082 0.90670791 1.02335443\n", + " 0.98233296 0.99151606 1.0643847 1.03969033 1.08502443 0.79830973\n", + " 0.80073052 0.95676193 0.98116028 0.83190328 0.91343548 0.96488295\n", + " 1.06650923 0.90421635 0.95303157 1.09465905 1.07842264 1.06064988\n", + " 1.03381408 0.95927114 0.95209276 0.95476949 1.12373465 0.9764688\n", + " 0.89788269 1.12562384 0.93634793 0.95112767 0.90993235 0.93123172\n", + " 0.90839171 0.79005081 0.95680102 1.05974716 0.89222202 0.96433866\n", + " 0.86013926 0.96954403 1.01800707 0.8546139 0.99400178 0.90046957\n", + " 0.95515291 0.89555865 0.96463509 0.97542993 0.76062643 1.01976874\n", + " 0.91371625 1.01296803 1.16761464 0.86405681 0.85940288 0.84901624\n", + " 0.961322 0.8853649 1.03240755 1.09282756 1.0582686 0.97615913\n", + " 1.07092681 1.03622101 1.13242353 0.94513265 1.10420882 1.09398704\n", + " 0.90392405 1.00287343 0.87426004 0.95353373 1.00423972 1.15282195\n", + " 0.92642633 1.02726548 1.09961707 1.10196001 0.95526778 0.99850358\n", + " 0.9299175 0.71153106 0.92492178 0.91911734 0.90496375 1.0560359\n", + " 0.83018137 1.01470491 0.93748026 0.93381658 1.0396781 0.95117681\n", + " 1.03891648 0.95291193 0.92972046 1.10927736 0.94541117 0.77244077\n", + " 0.8986492 1.17941398 1.10973725 1.01314031 0.98108618 1.05164962\n", + " 1.02824497 1.03257122 1.03255457 0.87539449 1.07916504 0.9372701\n", + " 1.01987329 1.05935737 1.1227104 0.93691796 1.09385777 0.93954998\n", + " 0.98463532 1.09201688 1.05532249 0.86348964 0.28497986 1.03508338\n", + " 0.9144048 1.03569389 0.88623459 0.8517852 0.97284546 0.88343987\n", + " 0.93246018 1.03807684 0.95927568 1.08822179 1.14241887 0.9794039\n", + " 1.0912476 1.17105619 1.00733372 0.9499505 0.77723851 0.9553672\n", + " 0.63970347 1.06922566 0.89930137 0.83539866 0.86579453 1.03265095\n", + " 0.97444264 1.10736886 0.99274923 1.05719293 1.10509205 1.18244716\n", + " 1.18197589 0.95061164 0.98734152 1.03674675 1.03118816 0.96821149\n", + " 0.8415231 0.91984721 0.90123214 1.10649042 0.87484199 1.11096457\n", + " 0.80542953 0.75734181 1.00161031 0.93393053 0.96641354 0.86810317\n", + " 1.03402745 0.91914951 0.9168397 0.94991551 0.88957818 0.88231241\n", + " 0.92088129 0.96883299 0.91619874 1.06988146 0.95248955 0.90171962\n", + " 0.86533417 1.08349 1.04284209 0.98929974 0.97544289 1.07066403\n", + " 1.00291403 0.95816408 0.92349372 0.74046173 0.97541474 0.90516995\n", + " 1.00635323 1.00632329 0.90460869 0.94101986 1.06189401 0.93060286\n", + " 0.86548054 0.93544486 0.93254304 1.0129833 0.95061175 0.90683773\n", + " 0.88853853 0.98255584 0.91474305 1.10819666 0.87282044 0.98319624\n", + " 0.90201955 0.9980095 0.95492366 1.01014606 1.04339851 1.04438811\n", + " 0.92685162 0.95695888 0.93808089 0.94277124 0.95126032 0.97861442\n", + " 0.95287238 1.06480476 1.06661607 0.91943395 0.9390805 1.06516211\n", + " 1.0162961 0.62879333 0.9048945 1.02400905 1.07808582 1.06754816\n", + " 1.13196697 1.09269156 0.84236832 1.08009309 0.99870547 0.87097401\n", + " 1.0378727 0.98838071 1.09975598 1.02055669 1.09022213 1.15971419\n", + " 1.15588799 0.85557819 0.91808862 0.90078535 1.03050155 1.12352585\n", + " 0.84238093 0.85176117 0.90034569 0.98887254 1.04366276 0.98884479\n", + " 1.01175392 0.99482038 0.90209062 1.11891912 0.98325245 1.12797318\n", + " 0.90787391 0.91128414 1.05562978 1.12476002 1.12515884 1.18611659\n", + " 1.1241141 1.13077948 1.24682286 1.13763513 0.98502705 1.18389314\n", + " 1.1275269 1.09887389 0.99844863 1.01032319 0.96989211 1.01902095\n", + " 1.03063124 0.85184889 1.03663465 1.12045824 1.07241014 0.84827262\n", + " 1.06891276 0.94178326 0.97640155 1.25424995 1.10952564 1.07707641\n", + " 1.04159983 0.91097926 0.94709074 1.08578436 1.12291252 1.09587783\n", + " 1.06031976 1.02719976 1.11599243 0.7766615 0.93267035 0.87681768\n", + " 0.88557382 1.00830325 1.15578183 0.83142329 0.81066989 0.96166708\n", + " 1.05495681 0.94570084 1.06865094 1.05429961 0.98655212 0.97120727\n", + " 1.06576466 1.06581906 0.90306465 1.13854317 0.98534803 0.78872527\n", + " 0.85589071 0.9724319 0.92203949 0.88964418 0.85906861 1.06078203\n", + " 0.82066271 1.05660442 0.98932137 0.67748615 1.04096299 0.8491599\n", + " 0.88636178 1.03712949 1.17872256 0.92172776 1.14845979 0.92383507\n", + " 0.89531017 0.77027701 0.81536138 0.89685088 0.83207501 0.93536151\n", + " 0.87800656 0.92621417]\n", + "Distances (cosine): [0.88854661 0.93535573 0.95566299 1.0992454 1.04232769 0.93908778\n", + " 0.97529726 0.93724327 0.98466445 0.98436148 0.92776596 0.95867325\n", + " 0.9015388 0.75926466 1.04239868 0.93745503 0.80905665 0.74836049\n", + " 0.98046743 1.12016825 0.7796834 0.73896959 0.95374754 1.04523808\n", + " 0.94908038 0.96700333 0.93094414 0.85313938 0.76004633 0.88508848\n", + " 0.81254694 0.94427531 1.0772097 0.93915077 0.98289886 0.9884915\n", + " 0.9798818 0.92793742 0.97571055 1.14765888 0.89771089 0.87803173\n", + " 0.93651781 0.94548152 1.01386854 0.80496964 0.84165258 0.78692748\n", + " 0.86488069 0.92018787 1.00571559 0.87486086 0.97893336 1.03088592\n", + " 1.00402299 1.08792789 0.79494837 0.84043649 0.96861954 0.96710154\n", + " 1.05617381 0.92933409 0.94203174 0.8996385 0.77335779 0.90791604\n", + " 0.93024941 0.88205115 1.16782275 0.85893835 0.87152914 1.00340627\n", + " 0.8198323 0.96938953 0.90388925 0.91710324 0.91447372 0.91702234\n", + " 0.77045147 0.96357584 1.03010885 1.01081402 0.98426977 1.00452193\n", + " 0.77699693 0.89529438 0.91415218 0.99691809 0.92864517 0.94082482\n", + " 0.92814063 0.93653862 0.95286705 0.79032246 0.85119332 0.83971469\n", + " 0.72490728 0.89813333 0.81672217 0.91562064 0.91878681 0.9847874\n", + " 0.88131843 0.8780673 1.15309324 1.06804647 0.94671827 1.00616375\n", + " 0.90943882 0.98291827 1.08008955 0.78618742 0.81880992 0.97145214\n", + " 1.13936336 0.92513142 1.03552611 0.95810136 0.84620437 1.01062855\n", + " 0.96586741 0.85223209 0.81876306 0.9231071 0.93232581 0.91601185\n", + " 0.85607175 0.86135248 0.93006385 0.7925004 0.8709093 0.79113817\n", + " 0.99869097 0.83779687 1.04647275 0.66552227 0.75222458 0.85527416\n", + " 1.10880217 0.94491016 0.8445618 0.88724102 1.01351084 0.90528557\n", + " 1.04940253 0.94038024 1.05252444 0.88527113 1.01624538 0.92180601\n", + " 1.0779799 0.9318702 0.93154812 0.87913256 0.92613203 1.06089638\n", + " 1.0496537 0.90248837 1.00136466 0.93624822 1.05784133 1.10248993\n", + " 1.02003456 0.94919126 1.04743428 1.06552364 1.00991393 1.00871286\n", + " 1.05407849 1.01087119 1.00124155 1.11737421 1.07620199 0.99554157\n", + " 0.67534583 1.06370219 0.98719407 1.05000781 0.98793233 0.93992445\n", + " 0.8648117 0.98183254 1.09041767 0.91530163 0.90750206 1.007404\n", + " 1.21502798 1.13061648 1.07138072 1.10673015 1.04533886 0.96634494\n", + " 0.86678847 1.01949455 0.7548848 0.9316641 0.89067766 0.98237388\n", + " 0.84723566 0.76028446 0.91058239 1.01143483 0.88421335 0.82849344\n", + " 1.06020214 1.09512101 0.9756496 1.19083574 1.05324559 1.02598073\n", + " 0.90213561 0.24359352 1.04870365 0.89487018 0.92296778 0.90318676\n", + " 1.1066017 1.17741352 1.06628709 1.16389887 1.17732702 0.92736167\n", + " 1.09003179 0.96235566 0.75124781 0.81434102 0.96731148 1.19494504\n", + " 0.99049415 0.95595134 0.99139012 0.90069196 1.01763937 0.71698978\n", + " 0.74405896 0.96077843 1.00700392 1.10036478 1.0933927 1.043796\n", + " 1.01470792 0.97665691 0.97497146 1.04839987 0.99490752 0.99951178\n", + " 1.14131467 0.88970852 0.90703467 1.02606924 0.9206474 0.96423554\n", + " 1.03287218 1.09474263 1.08178116 1.09447471 1.16832823 0.89540997\n", + " 0.9856401 1.02458196 0.60350519 1.14220224 0.95002545 0.98347149\n", + " 1.04132877 0.90594256 1.0215918 1.07208929 0.98809117 0.87789419\n", + " 0.97113009 1.01711889 1.08608649 1.04056247 0.82180229 1.09756644\n", + " 0.89244455 0.75109727 0.8188796 0.91826007 0.98833501 1.18054305\n", + " 1.00671416 0.92931991 1.02468582 0.99020217 1.13428362 0.89072088\n", + " 0.79158203 0.91734211 0.95559386 0.8490471 1.05446533 0.91023561\n", + " 0.91444439 1.00976131 0.87304203 1.02936048 0.98857838 1.03792764\n", + " 1.03887263 0.87399044 0.96547662 1.03734154 0.93361524 0.96989087\n", + " 0.80734265 0.90700398 0.93672325 0.95748053 1.09720091 0.90462571\n", + " 0.99092383 0.97185922 0.89905031 0.88163034 1.01038549 1.03074523\n", + " 0.79684087 1.01869718 1.02426256 1.04022714 0.88473702 0.96200774\n", + " 0.89911986 0.9937136 0.99364067 0.85127677 1.09413489 1.05929079\n", + " 1.11527708 1.13685375 1.01247729 1.15272817 0.97721515 1.11067388\n", + " 1.02703824 0.99002758 1.17909438 0.80831469 0.96752337 1.07454473\n", + " 1.02881676 1.01894465 1.15747444 1.06327284 1.10937509 1.0662275\n", + " 1.01290897 1.01346796 1.07741285 0.99996133 0.97171158 0.89470364\n", + " 0.96028581 0.88103325 0.8918453 0.74922088 0.93877911 0.9392977\n", + " 0.99862538 0.96946446 0.94156315 0.98249781 0.89994199 0.8818737\n", + " 1.00129569 0.7549443 0.75875039 0.82143113 0.82550065 1.12018777\n", + " 0.95560585 0.97731029 0.79310252 0.83403924 1.01919212 0.81186759\n", + " 0.85130953 0.90162415 1.24860577 1.01141824 0.82370449 0.95940567\n", + " 0.91333976 0.94908897 1.06640407 1.07150973 1.07467352 0.84610021\n", + " 0.85269014 0.97815795 0.98096578 0.85801584 0.84736488 0.94856694\n", + " 0.972406 0.9722913 1.00493065 1.0401883 0.95487611 0.9684137\n", + " 0.95025026 0.85532612 0.83462718 0.82656569 0.91015478 0.92844003\n", + " 0.83341569 1.07552053 0.94396092 0.93901193 0.94422024 0.94570562\n", + " 0.89300932 0.84843467 0.97828099 1.05355946 0.8682839 0.89917458\n", + " 0.86559981 0.86564598 0.93942669 0.95932969 1.03768357 0.92347587\n", + " 0.92277434 0.91165416 0.87949991 0.97673509 0.76170632 1.03767909\n", + " 0.94996485 1.03627748 1.13665196 0.87650808 0.88580915 0.88931871\n", + " 0.98560939 0.91527734 0.98914867 1.02984831 1.06844397 1.03695579\n", + " 1.08312421 1.07590316 1.15577791 0.87841788 1.07197609 1.09322074\n", + " 0.94215641 0.99104404 0.89665966 0.99563357 1.03463995 1.11967122\n", + " 0.89208439 0.9147318 1.01192715 1.07244082 0.85706129 0.87855845\n", + " 0.99499838 0.7456463 1.03799592 1.02368505 0.85342308 1.03088939\n", + " 0.81698497 0.93273533 0.82729722 0.83869122 0.81469767 0.78499204\n", + " 1.0412911 1.04575936 0.91847563 0.95084511 0.95042579 0.82522765\n", + " 0.85316874 1.06090088 1.07002173 0.94845731 1.02648298 1.00491015\n", + " 1.0508358 1.0421335 1.07715938 0.90897688 1.10427872 0.91174623\n", + " 0.99310208 1.03421372 1.10971465 0.95349792 1.04706729 0.94004187\n", + " 1.01363106 1.117531 1.05160972 0.94112959 0.33572468 0.97084519\n", + " 0.82163279 1.02819679 0.91100412 0.95597098 1.0529896 1.0432342\n", + " 0.90857113 0.98145161 0.93520873 0.99538878 1.08438753 0.99700416\n", + " 1.10187518 1.1265943 1.04552854 0.95757395 0.65224465 1.02114559\n", + " 0.74535156 0.95059508 0.85655671 0.75028233 0.84530511 0.93947761\n", + " 0.94882796 1.05765046 0.91592452 0.99029967 1.05794661 1.13767646\n", + " 1.04964906 0.88260439 1.05936722 1.00782229 0.91147532 0.99435287\n", + " 0.85978455 0.95126841 0.89534315 0.98904559 0.90862669 1.23398777\n", + " 0.78012026 0.7719898 1.0503023 0.96849657 0.90603306 0.90801825\n", + " 1.00757591 0.93336687 0.91882677 0.84470749 0.78403129 0.89981942\n", + " 0.94222481 0.96316751 0.97496465 1.07233092 0.95668892 0.89443414\n", + " 0.96271262 0.97755991 0.96799905 0.87366715 0.84264935 1.01705424\n", + " 1.05662739 1.03920871 0.87084573 0.83902794 0.99334965 0.97077595\n", + " 1.05495587 1.05705738 0.91891834 1.01370283 0.96762996 0.90008765\n", + " 0.92389428 0.98926664 0.98883443 0.99164297 1.00598475 0.9692271\n", + " 1.0040501 1.02159256 1.01696469 1.11158463 0.90283847 0.98645527\n", + " 0.93691934 1.0649083 1.032662 0.95134084 1.02888426 1.01829235\n", + " 1.00510291 0.95274305 0.91926869 1.04332504 0.93988296 0.89598364\n", + " 0.9289698 1.07964229 1.08443517 0.82637489 0.92479075 1.06170418\n", + " 1.06732813 0.70846525 0.859892 1.08786256 1.06125499 1.09323918\n", + " 1.1995612 1.14936838 1.02143421 1.12666261 0.97344578 0.7960604\n", + " 1.0210266 0.9129015 1.02397339 1.05973155 0.98411833 1.05859259\n", + " 1.02643828 0.95546207 1.01273753 0.97497776 1.03097955 1.03673751\n", + " 0.88663524 0.93046881 0.98481718 0.87127478 1.00985973 1.04663223\n", + " 1.05707287 1.00545479 1.01466676 1.10097553 0.99597789 1.00832186\n", + " 0.94005095 0.95161152 1.0502331 1.05781499 1.09599124 1.10272985\n", + " 1.10111051 1.04098684 1.06512838 1.09642362 1.03211982 1.0091015\n", + " 1.01408179 1.08261319 1.06687056 1.05388288 0.89824859 1.04448299\n", + " 0.99647922 0.75837944 0.93652012 0.97218199 0.98729871 0.85760041\n", + " 0.96287443 0.96080893 0.90712317 1.12434378 0.95547604 0.97889561\n", + " 0.98253368 0.9310875 0.86301799 1.03788749 1.03593835 0.98589283\n", + " 0.99745003 0.9960673 1.08923135 0.84030729 0.96328136 0.8224505\n", + " 0.81737212 1.03283699 1.09826853 0.79793883 0.7534206 1.00184691\n", + " 1.0184541 0.98870238 0.94042559 0.89773533 0.92146944 0.905453\n", + " 1.02989765 0.90711587 0.85863145 1.11191449 1.02635752 0.79206224\n", + " 0.90169724 0.94515589 0.95893484 0.92295073 0.84124368 0.99636405\n", + " 0.91138248 0.99453601 1.0235495 0.71193628 1.00723615 0.87498045\n", + " 0.88340703 0.989559 1.16255462 1.0048785 1.14901274 1.08011484\n", + " 0.95009866 0.77365269 0.8453254 0.92191271 0.89653263 0.99906851\n", + " 0.85348517 0.83262151]\n", + "Distances (cosine): [1.0707766 1.05280123 0.9955073 1.17160808 1.08158984 1.12031085\n", + " 0.92118866 1.05903729 1.13958094 0.85620418 0.89963888 0.91450554\n", + " 0.87559333 0.56488214 1.12598696 1.05489714 0.85154985 0.87269421\n", + " 1.13103236 1.1685046 0.86397561 1.02124688 1.17886701 1.1875973\n", + " 1.02783972 0.99565907 1.06847435 0.86179594 0.95589025 0.96976869\n", + " 0.90104044 1.08762538 1.35259132 1.12069541 0.93859056 1.17618556\n", + " 1.13213007 1.02420363 1.04806411 1.24254915 1.14539744 0.79004292\n", + " 0.96451416 1.12711291 1.0771372 0.79692315 0.86517961 0.72162279\n", + " 0.76688949 0.79993995 1.06285664 0.78942731 1.11239941 1.22366833\n", + " 1.09495333 1.06526128 0.90207844 0.96916852 0.95516145 0.90784846\n", + " 1.09070536 0.87251183 0.97037547 0.85331474 0.84954116 0.93874252\n", + " 1.1569516 1.01462285 1.29566637 0.79245699 0.75335928 1.0466561\n", + " 0.86098592 1.13171083 1.17231135 1.19100685 0.77839495 0.97397046\n", + " 0.83531213 1.14957035 0.94193767 1.07939276 0.97823706 1.16874725\n", + " 0.92773496 0.99416937 0.89072113 1.02999901 1.25049625 0.91774146\n", + " 1.20105933 1.052994 0.88800097 0.81103482 1.05202223 0.9100579\n", + " 0.81157463 0.97661432 0.85762017 0.86693153 1.00931338 1.14277468\n", + " 1.03151954 0.96114609 1.1692051 1.13029583 1.14015435 0.96348432\n", + " 1.05894499 0.99901679 0.98279746 0.80904084 0.94578394 1.04990323\n", + " 1.20607512 1.06188527 1.20115547 1.0557038 0.78506381 1.05653173\n", + " 0.98065749 0.79715656 0.84820726 1.02779077 0.7928568 1.09311799\n", + " 1.21482736 1.16284229 0.87710987 0.95833227 1.09038437 0.95680158\n", + " 1.02688945 0.89169632 1.09909908 0.61980567 0.63087263 1.17514766\n", + " 1.09503016 0.9240841 0.82125754 0.93721084 1.12379649 0.88617211\n", + " 0.94857259 0.83534591 1.14717976 0.87703866 1.03279811 0.84797477\n", + " 0.95687695 0.75843061 0.89241044 0.73669267 0.88678902 0.97519241\n", + " 0.91490703 0.82225793 0.94467426 0.76523249 1.0287892 0.95648406\n", + " 0.99154697 1.10012846 1.07942535 1.04017368 1.00063467 1.01732551\n", + " 0.94196829 0.92472687 1.02225475 1.12617411 1.17398001 1.13984747\n", + " 0.79310398 1.12481898 0.97835276 1.15064918 0.9573869 0.97662453\n", + " 0.92393886 1.08306903 1.20483003 0.83383811 0.93226026 1.159906\n", + " 1.19187156 1.19173845 0.97592162 1.12447657 1.0131322 0.9996813\n", + " 0.88470972 1.17916519 0.92069851 0.95534954 0.99883255 1.01778056\n", + " 0.87506954 0.70270725 0.84249383 1.01799434 0.80857697 0.96059062\n", + " 1.17313307 1.22847605 1.07144521 1.18944848 0.87675349 0.94737759\n", + " 0.82884484 0.65088536 0.96848544 0.97931229 0.85461497 1.06146485\n", + " 1.12841895 1.13208836 1.01549957 1.13389109 1.10949864 0.86936205\n", + " 1.16171667 0.99191634 0.69886441 1.01244771 1.06384391 1.16342043\n", + " 0.87714648 0.79509355 0.82465337 0.92394204 1.17326398 0.83171855\n", + " 0.72586251 0.97521097 1.23270537 0.95950087 0.90448721 1.09748251\n", + " 1.11664194 1.11381386 0.85843497 1.14389576 1.005197 0.92424425\n", + " 1.15166063 0.96106449 0.94491532 0.95296302 1.0005168 1.10315638\n", + " 1.1045582 1.10144251 1.08773441 1.10478829 1.05251734 0.79515185\n", + " 1.12874883 0.73995228 0.10969604 1.23824124 1.12607204 0.97018169\n", + " 0.84349875 1.01433251 1.08762463 1.07383379 1.11160222 0.84134066\n", + " 1.12378758 0.99942415 0.99125837 1.06813928 0.87961573 1.04047644\n", + " 0.89610017 0.85896746 0.87468646 0.94542567 1.00066046 1.20462196\n", + " 0.8019749 0.70664758 1.03514693 0.9561904 1.04864485 0.7093718\n", + " 0.62870155 1.05911608 1.06181346 0.87222819 1.05868497 0.84837236\n", + " 0.88730635 1.06601646 0.70433699 1.07299319 1.00986177 1.07600932\n", + " 1.17921435 0.91737088 1.09676001 0.94393789 1.01761549 0.93144638\n", + " 0.99679325 0.92311187 0.89198162 1.19355581 1.09076016 0.89926787\n", + " 0.92093785 1.13603794 1.07319538 0.89816184 1.17260584 0.8685913\n", + " 0.72768754 1.07962396 1.00187679 1.16232327 1.02152627 0.94809315\n", + " 1.10274643 1.00768191 1.08868491 0.67114737 1.03659213 0.98192373\n", + " 1.24505852 1.05650829 1.14276317 1.20663884 0.95341254 1.20778328\n", + " 0.98449955 0.78187294 1.06576426 0.99532712 1.12295518 1.15194253\n", + " 0.97219432 1.03066045 1.10710576 1.08129495 1.11898624 1.14102453\n", + " 1.18983583 1.08883795 1.24885187 1.01155629 0.97168047 0.95805238\n", + " 1.1544316 0.89415283 0.95257411 0.47803098 1.04583569 1.09083083\n", + " 1.22131604 0.99894557 0.97008813 1.04828543 0.8483809 0.6909563\n", + " 0.92722364 0.84583213 0.53728143 0.80789167 0.87926639 1.09680375\n", + " 1.02926318 1.05994729 0.92270033 0.9860167 1.08585048 0.79263545\n", + " 0.7101507 0.97877949 1.2687709 1.04134898 0.83306886 1.1589305\n", + " 1.09108209 1.05862219 1.15065944 0.9895469 1.13335957 0.87489193\n", + " 0.99816352 1.09310817 0.87937897 0.9975643 0.85158909 0.91528298\n", + " 1.14823249 0.9730438 0.95262801 1.04994024 0.90527764 0.90592552\n", + " 0.92390878 0.71703474 0.71430088 0.84390663 0.85046283 1.06762321\n", + " 0.85875198 1.20749691 1.08311771 1.06071818 1.00787347 1.13458033\n", + " 0.90840748 0.86493704 0.88905027 1.20236518 0.82467593 0.79638833\n", + " 0.94015004 0.89574558 0.84816608 1.12020455 1.18948709 0.96355574\n", + " 0.89144563 1.00294445 0.93029411 1.10587289 0.82399037 1.0332549\n", + " 1.07269309 1.06434346 1.16664526 0.9374199 0.96101422 0.98371068\n", + " 0.99968115 1.02873883 1.17144571 1.23749812 1.0685983 1.00944943\n", + " 1.13145731 1.13154877 1.15308064 1.08644582 1.06773066 1.18014143\n", + " 1.00819988 1.09432164 1.10547295 1.07079659 1.1055887 1.05713438\n", + " 1.06141331 0.80706438 1.1511425 1.27129729 1.01105695 1.00313801\n", + " 1.2067822 1.05971195 0.96269274 0.96931016 0.86215488 1.06673718\n", + " 0.99874871 0.87535304 0.72363765 0.47000197 0.4297472 0.38611815\n", + " 1.084379 0.99830932 0.9364342 0.99420145 1.07922776 0.63959544\n", + " 0.92583125 1.2054432 0.9701016 0.94517586 1.09821189 1.12033783\n", + " 1.0815286 1.04824306 1.10834837 0.99444181 1.12368013 1.05690306\n", + " 1.07400025 1.07397141 1.12357004 1.05428371 1.14635013 1.15813833\n", + " 1.16037201 1.08660616 0.99585101 0.99682737 0.67192031 1.02574674\n", + " 0.97536751 1.07420962 1.06855534 0.95389835 1.04703887 1.09578469\n", + " 1.06120072 1.07446243 1.01453858 1.14733232 1.07169658 1.17781383\n", + " 1.13943047 1.20070502 1.15549696 0.72363878 0.14631016 1.08108698\n", + " 0.5644057 0.86192329 1.00921063 0.92421146 1.11172979 0.85903813\n", + " 0.93092179 0.85038804 0.72389987 0.83811482 1.08522966 1.15344123\n", + " 1.05811808 1.04858699 1.18602912 1.11143411 0.8143762 1.0353329\n", + " 1.07940158 1.01631029 1.01519385 1.0912292 1.05080297 1.25230026\n", + " 1.08900922 0.79070553 1.1240446 1.09465309 1.17808774 1.03194985\n", + " 1.08374749 1.02921053 1.1533667 0.86490411 0.80882295 1.10369415\n", + " 1.01595574 0.96359154 0.96155064 1.03399784 1.08004809 0.89753643\n", + " 0.80933228 0.91130579 0.93737199 0.64478826 0.63983077 1.06906304\n", + " 1.07269409 0.89556035 0.87881538 0.82222404 1.08412663 1.07405611\n", + " 1.1609198 1.01921209 0.86552584 0.99198972 1.08774114 1.0038623\n", + " 1.04381888 1.17557574 1.10934508 1.0495157 1.00361621 0.98750459\n", + " 1.00600281 0.866933 1.22320141 1.15964127 0.9223702 1.01071476\n", + " 1.17040306 0.98981133 1.16337759 0.96342768 1.18193461 1.24729479\n", + " 0.93252344 0.93744735 0.89354138 0.90250084 0.97673168 0.71493482\n", + " 1.14241983 1.29748264 1.04069007 1.07716713 1.18216273 1.27673852\n", + " 1.05450868 0.7930859 0.97051747 1.05162784 1.10123659 1.20944247\n", + " 1.17396433 1.13823873 0.93590913 1.13667177 0.90678173 0.99935817\n", + " 1.017066 1.19018696 1.01791996 1.01858701 1.12630577 1.20055061\n", + " 1.07959903 1.02183581 0.98886601 0.95957267 1.09341253 1.12347024\n", + " 0.8995329 0.94747279 0.88998613 0.85633952 1.06037074 1.07226954\n", + " 1.167153 1.1829139 1.07442234 1.18923222 1.040901 0.99311155\n", + " 0.97054662 0.95859464 1.23908463 1.17653314 1.16161771 1.05212636\n", + " 1.19685325 1.19860524 1.12264061 1.12272311 1.11960892 1.07556301\n", + " 1.16410659 1.2426215 1.17736136 1.18240592 0.99457873 1.07010627\n", + " 1.08507805 0.60804181 1.15316131 1.00758689 1.13266134 0.92026177\n", + " 0.84988191 1.0884377 1.05789948 1.10768988 0.95437437 1.01191592\n", + " 1.07748736 0.97389829 1.05961888 1.16361625 1.13197989 0.76352389\n", + " 1.19451366 1.06339147 0.82791458 0.96113329 1.02483405 0.86196949\n", + " 0.96858477 1.15501349 1.21126379 0.88359168 0.99246154 1.18522045\n", + " 1.24626845 1.06376186 0.88397772 0.86386253 0.86948727 0.81432838\n", + " 1.01676635 0.83541524 0.72698901 1.10348465 0.9917887 0.726935\n", + " 0.6704033 0.81560704 0.80335049 0.93920711 0.79580004 0.64225906\n", + " 0.89948641 1.11563232 1.06917206 0.95443525 0.97173503 1.11851539\n", + " 0.95034211 0.86768788 1.10490141 0.98360433 1.11956416 1.07092587\n", + " 0.97862622 0.70046117 0.85149563 0.92829699 0.97894423 1.08528323\n", + " 0.90993579 0.75658906]\n", + "Distances (cosine): [0.87305379 0.92188638 1.10964091 1.00927031 0.91277953 0.76351853\n", + " 0.95577331 0.89604419 0.794972 0.97523842 0.92141706 0.91347802\n", + " 0.92553099 1.03385599 0.87806024 1.04314092 0.90358162 0.93587011\n", + " 0.8601977 0.72684806 0.87189268 0.89277431 0.81435519 0.70403952\n", + " 1.15409355 1.18083872 1.1668457 1.15052955 1.15459624 1.02288806\n", + " 1.02935228 0.84968761 1.14120797 1.17632339 0.85756496 1.04557821\n", + " 1.11232829 0.81956018 0.84660796 1.0175985 0.84172803 0.69740249\n", + " 0.64336418 1.0110396 0.89424831 0.92664214 0.85008909 0.64665824\n", + " 0.96393216 0.99999916 0.84598545 1.01016859 0.80532136 0.95602702\n", + " 0.86843674 1.01042381 0.85683756 0.7077735 0.8944971 0.88039301\n", + " 1.13042098 1.20978352 0.8577241 0.87518391 0.95276923 1.13160609\n", + " 1.22488992 0.94769587 0.8426951 0.58069002 0.6692809 0.91142602\n", + " 0.57506243 1.01284375 1.01354465 0.98413037 0.87525764 0.79996122\n", + " 0.86086868 0.77697342 0.81600731 0.8784266 1.09702522 1.0939861\n", + " 0.90135922 1.04362861 1.01470519 0.792187 1.05513573 0.99680184\n", + " 0.97572777 0.98412073 1.0619824 1.0562335 0.90146452 1.02031978\n", + " 0.86964554 1.02522917 0.72419191 1.01134527 0.94735918 0.99067358\n", + " 1.00375463 0.85546666 1.21158773 0.82921225 1.13043585 1.22443928\n", + " 0.70939298 0.88719338 0.93792206 0.97469568 0.983875 0.91482246\n", + " 0.96100239 0.84527578 0.91937779 0.9840862 0.82557912 1.12079413\n", + " 1.14925562 0.84066792 0.57027969 0.84071859 1.00337804 0.99784433\n", + " 1.02290304 1.10867573 0.96311733 1.11357673 1.1462676 1.03603198\n", + " 1.13138332 1.05201547 1.1190262 1.01230234 1.04833681 1.05807128\n", + " 0.93470885 1.09918985 0.98297562 1.10190927 1.03616786 0.9409892\n", + " 0.91581863 0.97093109 0.88648859 0.94392895 0.92131744 0.99960814\n", + " 1.11194778 1.00402307 1.09605958 1.01892813 1.1857783 0.98046061\n", + " 1.05058251 1.05276888 1.05823415 0.96589646 1.13139313 1.13420731\n", + " 1.1021916 0.87553887 0.85132516 0.87677475 1.15839027 0.98635765\n", + " 1.10405201 1.07118413 0.98175021 0.98153933 0.95209845 0.97097428\n", + " 0.91469509 0.93631047 1.03589345 0.9223157 1.10301058 0.84372179\n", + " 0.92405887 1.01700208 0.85560625 0.66376932 0.62879869 1.17535327\n", + " 1.17288113 1.12936734 0.85630628 0.9935012 0.79078083 0.83314447\n", + " 0.69793571 1.1177419 0.87474965 0.95546112 0.7140535 0.78362202\n", + " 0.93636762 0.88706518 0.98854831 0.53318995 0.9112592 0.9089143\n", + " 0.75849555 0.68877587 0.88360259 1.0160993 1.01399431 0.82711715\n", + " 0.85090735 0.91536395 0.77050502 0.81631043 1.07070628 0.98872353\n", + " 1.01001572 0.97150056 0.84340552 0.99123647 0.91783032 0.92315487\n", + " 1.04613481 0.86962825 0.78006934 0.83122908 1.00513335 1.15972018\n", + " 0.8429556 0.95364582 0.61769342 1.05107173 0.57762401 0.78019883\n", + " 0.8785505 1.05474182 0.81710598 1.06734876 1.03190654 1.050957\n", + " 1.02658854 0.84666405 1.0093965 0.94093656 1.00778426 1.1074735\n", + " 0.98381487 1.0724729 0.99977569 0.97708577 0.923541 1.13391103\n", + " 1.02111798 0.93046956 0.97238313 0.95116562 0.91564976 1.00064709\n", + " 1.02093509 0.94068727 0.86237653 1.00018309 0.77847054 1.09295294\n", + " 1.01678288 0.80845244 0.71169169 0.88203131 0.9863562 0.82288704\n", + " 0.84434346 0.95841932 1.04595906 0.91983848 0.9188853 0.94738375\n", + " 0.59065689 0.84913679 0.80816558 0.62399018 0.57594035 1.11249105\n", + " 0.79668246 0.98954696 0.73444014 0.92594717 0.98615711 0.65543418\n", + " 0.73419254 1.07349907 1.09006532 0.94969844 0.90211171 0.67909127\n", + " 0.972697 0.96793238 0.75460412 0.95481894 0.94084261 0.72800249\n", + " 0.81684544 1.20408444 0.88243765 0.91681268 0.91178225 1.02867303\n", + " 0.72027834 0.73994017 0.86507523 0.84182556 0.72280821 1.00716482\n", + " 0.7813304 0.77786768 0.92744098 0.85386407 0.93780078 0.93450547\n", + " 1.09329797 0.97965232 0.93129151 1.04902224 1.14356557 0.74093314\n", + " 1.12139284 0.73946144 0.90542022 0.72771143 1.04499595 0.99297089\n", + " 0.8513203 0.9776011 0.95937969 1.01517576 0.86413594 0.96717272\n", + " 0.83557305 1.07126071 1.03054722 1.0613062 1.02719786 0.96788921\n", + " 0.86524413 1.18237412 0.87348863 0.91545788 0.85860723 1.03962687\n", + " 1.11498402 1.08390092 1.10431583 1.01675099 0.79878511 1.13491973\n", + " 0.73188063 0.8455133 0.51351895 0.87142331 0.81459734 0.98342172\n", + " 0.97600834 0.48404321 1.06702925 0.92098292 0.73439884 0.81202441\n", + " 0.86378087 0.8029987 0.83480071 0.93941543 0.70800905 0.77485544\n", + " 0.87576174 0.73419887 0.93942517 0.85130773 0.91783885 1.02111565\n", + " 0.93768646 1.0693141 1.16333718 0.95295644 1.0527556 0.83745164\n", + " 0.98366661 0.94934376 0.89209662 0.95559417 0.85204521 0.60885469\n", + " 1.070234 1.06721 1.03532569 1.05480828 0.99881521 0.8012916\n", + " 1.14323032 0.91441495 1.10883449 1.04013935 1.20607014 1.11743984\n", + " 0.90860225 1.07648507 1.11825964 0.92849238 0.65810364 0.885797\n", + " 0.70967654 0.91669225 0.98230321 1.12278505 0.92942713 0.87650561\n", + " 0.97783624 0.91096721 0.98055912 0.76593545 0.71370887 0.6819643\n", + " 1.01936116 1.16272168 1.03158326 0.99730534 0.86422834 0.99842231\n", + " 0.71714957 0.76988248 0.80245735 1.15759927 0.84638889 0.98602918\n", + " 1.03589439 1.00618663 0.88795536 1.01789816 1.03019386 1.06129106\n", + " 1.18554105 1.06752199 0.94145773 1.03386674 1.07043105 1.08696959\n", + " 0.83686705 1.03079766 0.98600526 1.00050079 1.12573855 0.84908867\n", + " 1.15602068 0.96037746 0.81744958 1.02913338 0.75246943 0.97680999\n", + " 1.06694479 0.8708394 0.9573243 1.03692169 0.82906066 0.91166574\n", + " 0.90316753 0.8377321 0.74793776 1.04323352 0.73062325 1.07208996\n", + " 0.97261617 0.9763269 1.00007634 0.76443776 0.90001959 0.98829049\n", + " 1.05536892 0.85672581 0.88134835 0.89184656 0.76474907 0.52445101\n", + " 1.08993664 0.89805219 1.07821231 0.74792553 0.97528409 0.95903345\n", + " 0.78511278 0.70716597 0.95115371 0.84988213 0.93965363 0.80432173\n", + " 1.02343944 1.01158008 1.00014353 1.10379588 0.80695574 0.99468709\n", + " 0.9853186 0.90415822 0.79189411 0.9472948 1.01916826 0.92256528\n", + " 0.83215536 0.85473224 0.96014077 0.96279196 0.97937331 1.09123444\n", + " 1.00141688 0.8586851 0.94895783 0.91671689 0.86506038 0.91685519\n", + " 0.98937466 1.00141994 0.88197692 0.91925865 0.82800563 0.99232152\n", + " 0.85500613 1.06178381 1.15467249 1.033186 1.10492143 1.2063439\n", + " 1.01802737 1.24300977 1.25272725 1.14620797 0.88937241 0.68586874\n", + " 0.64438791 0.99760918 1.18024627 1.0070797 1.07223295 0.9562927\n", + " 1.07629201 1.02175338 0.92197925 0.88499438 1.0098337 1.0526718\n", + " 0.96735408 0.53145849 0.80276512 1.04651752 0.97209258 0.76439374\n", + " 0.81577401 0.86905004 0.86286669 0.76308561 0.83980759 0.71727065\n", + " 1.04954725 0.87153048 0.7838484 0.9176393 0.76039787 1.1167635\n", + " 0.74122103 1.12492674 0.87911194 1.04390272 1.09548012 1.08954162\n", + " 1.1005875 0.96698949 0.93585513 1.10773671 0.84880341 0.88412785\n", + " 0.91236299 0.94670779 0.54057727 0.77007672 0.97737834 0.9210275\n", + " 0.85361226 0.89533784 0.74488914 1.2209995 0.73041405 0.70377233\n", + " 0.91471134 0.75912198 0.93797381 0.89656991 0.57592883 0.91659749\n", + " 0.81583877 0.96728831 0.95159157 0.82056786 0.84052262 0.86088422\n", + " 1.13699011 1.05006497 1.0835101 0.99084507 0.94382648 1.15837877\n", + " 0.70257778 0.99223628 1.07253359 0.95474302 0.88414868 1.13538438\n", + " 0.92086584 0.52098149 1.10947306 0.86383603 0.98453589 0.91980584\n", + " 0.9794295 0.95321669 0.91434376 0.89442409 0.80853004 0.79286018\n", + " 0.9212393 0.94564519 0.76343841 0.91216478 0.91379791 0.91572645\n", + " 0.91650522 1.01703703 0.96955736 1.07443054 0.89513236 0.67374208\n", + " 0.68661692 0.68778005 0.68828047 0.4513123 0.89804119 0.96278955\n", + " 1.03298267 1.04320317 1.08934673 1.11959835 1.0920206 0.69222218\n", + " 0.58834938 0.6514184 0.89783974 0.97300552 0.96230626 0.98893337\n", + " 0.96572565 0.90166317 0.8900099 1.07975706 0.8670314 0.89416673\n", + " 0.82507204 0.92799422 0.90850361 0.90906859 0.8632283 1.03008551\n", + " 0.85548517 0.72650441 0.83310785 0.56523309 0.73956873 0.65958911\n", + " 0.60872293 0.59206699 0.55207605 0.69466705 0.64329664 0.79891409\n", + " 0.88649738 0.40988109 0.69232309 0.6928725 0.58083218 0.45271609\n", + " 0.69991926 0.80975737 1.18652812 1.00406657 0.95688882 0.88437406\n", + " 0.96081691 0.89072634 0.7472389 0.85757252 0.86936642 0.84703002\n", + " 0.73760414 1.1563862 0.82755653 0.89650233 0.9514573 0.73569208\n", + " 0.65579139 0.77822016 0.66345922 0.95236423 1.17516738 0.90904011\n", + " 0.80435753 1.14731959 0.84174958 0.93760161 1.05460773 0.9373178\n", + " 1.09264623 0.79324683 1.05347834 0.94208993 1.06613501 0.96750374\n", + " 0.71402425 0.59995847 0.97689021 1.08359431 0.9742434 1.00554383\n", + " 1.07059112 1.01876387 0.97681089 1.02678879 1.06284573 1.00626847\n", + " 0.66106635 0.86408993]\n", + "Distances (cosine): [1.01421002 1.07077005 0.96594289 0.95000596 0.93541515 0.91584817\n", + " 1.10235789 0.98789354 0.95672152 1.13044422 1.17682692 1.1313685\n", + " 1.11347398 1.07404553 0.91428485 0.99998853 0.85286168 1.06301463\n", + " 0.9042512 0.74559444 0.88334968 1.10095713 0.94990308 0.72190936\n", + " 1.04197876 1.26943121 1.25313551 1.16132919 1.149733 1.09759273\n", + " 1.05385586 0.97760032 1.19306924 0.89137526 0.82278112 1.10918612\n", + " 1.1552922 0.93129301 0.8070838 1.05320638 0.88975955 0.74838447\n", + " 0.90379122 1.10079649 1.03759931 1.06441512 0.91374018 0.89799835\n", + " 1.12001878 1.12568702 1.02814114 1.00965223 1.03077759 1.12487169\n", + " 0.89924438 1.0375218 0.82881765 0.74997263 1.02629928 0.9143763\n", + " 1.05566307 1.22149654 0.9382606 0.81491388 0.96719048 0.93176536\n", + " 1.0310118 1.15458284 0.94428458 0.89323419 0.81143344 1.05221236\n", + " 0.69612361 1.02231484 1.06812633 1.04262615 0.95776369 0.97006009\n", + " 0.74432267 0.78653623 0.79066271 0.9086223 1.03392748 1.16493876\n", + " 0.85881669 1.05501108 1.00985656 0.92049043 1.03236735 1.00606309\n", + " 0.95556721 0.93928631 0.87454242 0.87921475 1.02666891 0.95239818\n", + " 1.03699923 1.07272994 1.03851969 1.05823531 1.06117864 1.09019676\n", + " 1.08201718 1.03136059 1.17390947 0.65324844 1.04656484 0.94680156\n", + " 0.78535461 0.92627034 0.83182643 0.91454836 1.01546203 1.08613179\n", + " 0.85707615 0.89915109 0.99945264 0.99790772 0.75359248 1.11661919\n", + " 1.13690042 0.94200297 0.66797856 0.7792418 0.90760114 1.1652812\n", + " 1.01076802 1.00083519 1.02135328 1.07008462 1.0465478 1.03141616\n", + " 0.93089314 1.02566364 0.91768844 1.00117691 1.06147185 0.96244662\n", + " 0.94202731 1.14518485 0.88701054 1.02602909 1.12298608 0.89767381\n", + " 0.80849978 0.75235089 0.87350399 0.82984094 0.98612795 1.03116154\n", + " 1.02569068 1.19009324 0.94705876 0.89758241 1.06794324 1.1173812\n", + " 1.00002239 0.95118379 1.0819254 1.03390323 1.18389165 1.22619294\n", + " 1.07125352 1.03673406 1.13721381 1.14358808 1.03921018 1.10929593\n", + " 1.15356524 0.94299601 0.93255633 1.0354042 0.99992875 1.22094772\n", + " 1.04773202 0.99620774 0.95986149 1.00901921 1.05818082 0.85289335\n", + " 0.9805151 0.87018584 0.89484673 0.72701963 0.60590436 1.25597944\n", + " 1.02992865 1.19245666 0.85618525 0.92386848 0.99500744 0.89953438\n", + " 0.92721279 1.13542935 0.99860195 0.86375199 0.98436443 0.8571092\n", + " 1.02477788 0.86434522 0.98546864 0.54109603 0.91179237 1.17826994\n", + " 1.01493297 0.80387181 0.96187848 1.12834705 0.73258123 0.95054157\n", + " 0.95886944 0.82537672 0.95843735 0.90205049 1.1389638 1.02918902\n", + " 1.13644089 1.00706689 0.85336445 0.98860358 0.92251491 1.00177095\n", + " 1.11650379 1.01275352 0.89363632 0.92761628 1.04450738 1.17055077\n", + " 0.52432958 0.78422291 0.63371012 0.88070685 0.77349489 0.76910225\n", + " 0.80331347 1.0364185 1.02270963 1.038215 1.02398675 1.08763204\n", + " 1.07846679 0.79504672 1.00124499 0.93957569 0.88239396 0.93534626\n", + " 0.92568717 0.94234442 1.04472507 1.10432267 0.86822146 1.13413591\n", + " 1.18371492 0.84757253 0.91152468 0.8497535 0.95699655 0.83152117\n", + " 0.99178947 0.98940031 0.90993428 0.96007603 0.93210841 0.90804934\n", + " 0.82659429 1.06024528 0.97579451 1.07108973 1.08036627 0.79050503\n", + " 0.82850289 0.90130659 1.17613077 0.96398701 1.00363551 1.1321008\n", + " 0.97132952 1.03844101 1.03351224 0.60551334 0.78085424 1.01640911\n", + " 1.01448868 1.01384401 1.06170593 1.15045849 1.19076579 0.90208136\n", + " 1.02779955 1.09864822 1.10792748 0.96750283 0.95959741 0.93257905\n", + " 1.03840682 0.93295935 0.86031756 0.95326759 0.97571473 0.81369039\n", + " 0.91639636 1.14217286 1.04321351 1.0297567 1.01640227 1.00399503\n", + " 0.88814263 1.00590476 0.98255543 0.99304061 0.81652194 1.03879372\n", + " 0.90157022 0.92704159 1.01558832 0.94303023 1.0617102 0.83778088\n", + " 0.92947139 0.85321749 1.04188043 1.10544022 0.94910453 0.93977329\n", + " 1.03304495 0.73600388 0.91251683 0.70609508 1.08298935 0.98619713\n", + " 0.95332587 0.91133852 1.02360999 0.89181471 0.94127942 0.92755766\n", + " 0.84427062 0.80308185 0.99208308 0.96888637 0.90540487 0.9704813\n", + " 0.9556628 1.08476948 0.98662139 1.08956675 0.97182913 1.13644314\n", + " 1.27332452 1.20308043 1.2421625 1.05334428 0.81667924 0.97116698\n", + " 0.63704335 0.73666235 0.77787665 0.90978332 0.89015694 1.12392825\n", + " 1.14062722 0.75033401 1.09300461 0.9408243 1.00381744 0.74848446\n", + " 0.96713376 0.86305515 1.13419239 0.96432476 0.77037546 0.84067363\n", + " 1.01825012 0.94936511 0.81483043 0.96499299 0.99398247 1.03000178\n", + " 0.91531934 0.96068388 1.06621781 1.09488141 0.86857553 1.07615135\n", + " 1.14380331 1.05312301 0.93004361 0.67851594 0.78098376 0.70293232\n", + " 0.99674313 1.08279052 0.896288 1.18405943 0.90918565 0.92743257\n", + " 1.20862071 0.96499365 1.01244794 0.99499359 1.04211016 1.09437652\n", + " 0.81155586 1.0487013 1.06532539 0.9075846 0.63002966 1.10142332\n", + " 0.89745108 1.05955488 0.97285254 1.17514401 0.79508738 1.02933105\n", + " 1.02489202 0.97172641 0.85938453 0.85515589 0.83397013 0.79571494\n", + " 0.86277216 1.19613552 1.09584571 1.24039174 1.04764324 1.18246217\n", + " 0.89224625 0.94691471 0.87181621 1.24564567 0.99619212 0.98045941\n", + " 1.06649087 0.96221909 1.08993609 1.02991318 0.93683735 0.97603669\n", + " 1.02013848 0.95627047 0.83133649 0.96387518 0.93777374 1.05786982\n", + " 0.76992705 0.86717048 0.98895409 0.78083838 1.03101534 0.87823277\n", + " 1.15278151 1.08899768 1.03725794 1.04965223 0.67227334 0.87647351\n", + " 1.02318319 0.92246892 1.16992703 1.24351822 0.85151466 0.99091382\n", + " 0.8558565 1.01948401 0.84946348 0.9439263 0.83183478 1.18141189\n", + " 1.16745156 1.08540768 1.15561904 0.89934233 0.97343327 0.98482588\n", + " 1.19028892 0.92623536 0.99067947 0.89845048 1.01340538 0.74883602\n", + " 1.01493956 0.97937797 1.05470955 0.91764394 0.93633508 1.06238751\n", + " 0.94549371 0.83888775 0.9070468 1.05510956 0.90462685 1.0087438\n", + " 0.97107829 1.01522246 0.9302662 1.15726902 0.80284027 1.19252622\n", + " 1.1821632 0.99839991 0.9149796 1.11836941 1.02756323 1.0182542\n", + " 0.87873097 0.91207395 1.12175608 0.84843169 0.96426943 1.02251518\n", + " 0.99960288 0.97741411 0.9949037 0.87435148 0.89602769 1.02221796\n", + " 1.08462531 1.05837634 0.99632494 1.09367002 0.9095804 0.9188991\n", + " 0.85381149 1.06659725 1.159693 1.09341479 1.1403699 0.89690222\n", + " 1.04092955 1.01145248 0.8841497 0.96721476 0.91119218 0.66088694\n", + " 0.61161225 1.07549558 1.1109724 1.11380774 1.10473141 1.03202546\n", + " 0.93158237 0.99992473 0.95661108 0.85383709 1.04085812 0.87950328\n", + " 0.95318781 0.7419186 0.74702882 0.92180698 1.04993126 0.89625706\n", + " 0.93371683 0.99358931 1.06869572 0.91614501 0.86268864 0.96742496\n", + " 0.90234201 1.08079229 1.01990914 0.9999955 0.99433874 1.16764531\n", + " 0.84518952 1.13310209 0.84835348 1.08407546 1.09726991 0.76191091\n", + " 0.8213361 0.86287135 0.95555861 0.90950468 0.87899726 0.96723498\n", + " 0.91575199 0.98808816 0.776629 0.95730194 0.96463284 0.91534593\n", + " 1.07197091 1.01621825 0.87348515 1.25385266 0.69540447 0.76464481\n", + " 0.82080954 0.65302985 1.08651262 0.77160154 0.68150335 0.83261548\n", + " 0.92683973 1.08051067 1.01852538 0.98614617 0.94455482 1.00702254\n", + " 1.00008084 0.93580731 1.0616711 0.83148347 0.89916151 0.90136532\n", + " 0.86074004 1.04695182 1.11714621 1.00615707 0.96007462 1.13313071\n", + " 1.08832412 0.68294223 1.16511034 0.95802863 0.93620386 0.971089\n", + " 0.92962849 0.91312085 0.94873158 0.89717467 0.90195928 0.90336084\n", + " 0.97513478 0.94689992 0.95390285 0.92717124 1.05760276 1.05877296\n", + " 1.02209879 0.94824176 0.95708108 1.1078558 0.97412374 0.71985515\n", + " 0.92989838 0.93398248 0.83825691 0.5599142 0.84831357 1.10500717\n", + " 1.10366733 1.14147034 0.99173896 1.04376495 1.26199013 0.66706478\n", + " 0.85287327 0.9593587 1.11194832 1.05604997 1.08785454 1.01055063\n", + " 0.97724822 0.8655906 0.89004955 1.10082832 0.95885093 0.96468762\n", + " 0.84384673 1.03736174 0.95476951 1.0261436 0.78837881 0.97450544\n", + " 0.83222128 0.62927318 0.82400375 0.52147976 0.69180839 0.82185185\n", + " 0.11017399 0.76714388 0.64540427 0.63702853 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1.03997491 1.16117756 1.15281189 0.9323813\n", + " 0.98735978 0.91952159 0.87943963 0.93954764 0.91345122 0.89631903\n", + " 0.99915507 0.86971601 0.82593144 0.7982662 0.85422708 0.9667324\n", + " 0.92981673 0.96037634 1.08780012 0.77866837 0.89718166 0.95977864\n", + " 0.95665853 1.00411929 0.92896315 0.90276323 0.78958691 0.79988992\n", + " 0.91085182 0.96278792 1.11608588 1.08583426 1.02601674 0.99967455\n", + " 0.86742896 0.86785954 0.95867451 1.03448778 0.89492161 1.11519812\n", + " 0.99044153 0.8032279 0.99573059 0.99736843 1.11718126 1.10893809\n", + " 0.91764254 1.07144824 0.91677664 1.08635095 0.96073935 0.84565667\n", + " 1.12474471 1.11257326 1.14854123 1.02461483 0.97037398 1.02438511\n", + " 0.83325551 0.99049576 0.98067024 0.84589078 1.00408083 0.77514052\n", + " 0.70053144 0.77964524 0.82221173 0.85468024 0.74594541 1.13188377\n", + " 1.10441471 1.11355709 0.89050676 1.12608295 0.99680972 1.17192754\n", + " 1.05165017 0.8023706 0.96989638 0.67172585 0.83678269 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0.89608998 0.96241334 0.89650858 0.930984\n", + " 0.77174474 1.04979684 0.94253265 1.04147305 0.92809325 0.98269462\n", + " 1.04353906 0.9642066 1.0944907 0.93020661 1.0156857 1.07081341\n", + " 0.68065332 0.82251706 0.98487342 0.72087942 0.68806895 0.93118888\n", + " 1.10284038 0.8314337 1.22696603 1.15890645 0.82364241 0.94209504\n", + " 0.93601577 0.88376627 1.09834846 0.84905004 1.04538741 0.65747376\n", + " 0.94476483 0.57224291 0.84547182 1.11025435 1.12674861 1.07664702\n", + " 1.05432301 1.13812773 1.17453089 1.16646877 1.06711601 0.99928977\n", + " 0.75375513 0.87712715 0.92613822 0.87232553 1.08271649 1.19657827\n", + " 1.18730882 1.12355287 0.92409291 0.86854405 1.04320894 0.95783165\n", + " 1.08911796 0.98543132 1.16160252 0.924158 0.92937278 1.04553755\n", + " 1.09180412 0.95329214 1.00248517 1.14575957 1.04231661 1.07935577\n", + " 0.87976354 1.0738666 1.03929065 1.15766744 0.53016505 0.98245035\n", + " 1.10816885 0.89769466 0.46896295 0.61994693 0.25177224 0.94149321\n", + " 0.79691966 0.59284655 0.72498255 0.94286425 0.73706125 0.40466257\n", + " 0.48916059 0.71715084 0.78906761 0.76742211 0.75555709 0.68339005\n", + " 0.38268267 0.22474446 1.122836 1.04328393 1.18118839 0.79179384\n", + " 0.98134567 0.72829315 0.84669564 0.78723765 0.94099877 0.77215897\n", + " 0.86226458 0.99791484 0.99057288 1.02914502 1.03741296 0.97359336\n", + " 1.07590738 1.08905354 1.03744072 0.95284078 1.06829615 1.10371385\n", + " 0.98201801 1.07481656 0.84123079 1.0025847 1.10424004 1.11079413\n", + " 0.76107916 0.68111323 0.70079031 0.927157 0.80227648 0.81733981\n", + " 0.80325203 0.8630462 1.00162612 1.05606058 1.00803951 0.920244\n", + " 0.51312745 1.01635234 0.95242251 1.0521877 1.06687457 1.1582277\n", + " 0.93555897 1.07386927]\n", + "Columns: Index(['Country', 'Histologic_Grade_FIGO', 'Histologic_type',\n", + " 'Path_Stage_Primary_Tumor-pT', 'Path_Stage_Reg_Lymph_Nodes-pN',\n", + " 'Clin_Stage_Dist_Mets-cM', 'Path_Stage_Dist_Mets-pM',\n", + " 'tumor_Stage-Pathological', 'FIGO_stage', 'BMI', 'Age', 'Race',\n", + " 'Ethnicity', 'Gender', 'Tumor_Site', 'Tumor_Focality', 'Tumor_Size_cm'],\n", + " dtype='object')\n", + "Topk matches: [{'source_column': 'Country', 'top_k_columns': [ColumnScore(column_name='country_of_birth', score=0.5170051943814018)]}, {'source_column': 'Histologic_Grade_FIGO', 'top_k_columns': [ColumnScore(column_name='tumor_grade', score=0.6650353057554459)]}, {'source_column': 'Histologic_type', 'top_k_columns': [ColumnScore(column_name='history_of_tumor_type', score=0.6613978065162984)]}, {'source_column': 'Path_Stage_Primary_Tumor-pT', 'top_k_columns': [ColumnScore(column_name='uicc_pathologic_t', score=0.6776191475935113)]}, {'source_column': 'Path_Stage_Reg_Lymph_Nodes-pN', 'top_k_columns': [ColumnScore(column_name='ajcc_pathologic_n', score=0.6276434644871174)]}, {'source_column': 'Clin_Stage_Dist_Mets-cM', 'top_k_columns': [ColumnScore(column_name='uicc_pathologic_m', score=0.7378922945435357)]}, {'source_column': 'Path_Stage_Dist_Mets-pM', 'top_k_columns': [ColumnScore(column_name='uicc_pathologic_m', score=0.7113686845189913)]}, {'source_column': 'tumor_Stage-Pathological', 'top_k_columns': [ColumnScore(column_name='ajcc_pathologic_stage', score=0.7664999691570722)]}, {'source_column': 'FIGO_stage', 'top_k_columns': [ColumnScore(column_name='figo_stage', score=0.7460380829626372)]}, {'source_column': 'BMI', 'top_k_columns': [ColumnScore(column_name='bmi', score=0.761187469736605)]}, {'source_column': 'Age', 'top_k_columns': [ColumnScore(column_name='weight', score=0.700687201695624)]}, {'source_column': 'Race', 'top_k_columns': [ColumnScore(column_name='race', score=0.7150201421760489)]}, {'source_column': 'Ethnicity', 'top_k_columns': [ColumnScore(column_name='ethnicity', score=0.7564064760060497)]}, {'source_column': 'Gender', 'top_k_columns': [ColumnScore(column_name='gender', score=0.890303961909301)]}, {'source_column': 'Tumor_Site', 'top_k_columns': [ColumnScore(column_name='tumor_level_prostate', score=0.5901189146773462)]}, {'source_column': 'Tumor_Focality', 'top_k_columns': [ColumnScore(column_name='tumor_focality', score=0.8898260142520747)]}, {'source_column': 'Tumor_Size_cm', 'top_k_columns': [ColumnScore(column_name='tumor_width_measurement', score=0.775255538156757)]}]\n" + ] + }, + { + "data": { + "text/html": [ + "
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sourcetarget
0Countrycountry_of_birth
1Histologic_Grade_FIGOtumor_grade
2Histologic_typehistory_of_tumor_type
3Path_Stage_Primary_Tumor-pTuicc_pathologic_t
4Path_Stage_Reg_Lymph_Nodes-pNajcc_pathologic_n
5Clin_Stage_Dist_Mets-cMuicc_pathologic_m
6Path_Stage_Dist_Mets-pMuicc_pathologic_m
7tumor_Stage-Pathologicalajcc_pathologic_stage
8FIGO_stagefigo_stage
9BMIbmi
10Ageweight
11Racerace
12Ethnicityethnicity
13Gendergender
14Tumor_Sitetumor_level_prostate
15Tumor_Focalitytumor_focality
16Tumor_Size_cmtumor_width_measurement
\n", + "
" + ], + "text/plain": [ + " source target\n", + "0 Country country_of_birth\n", + "1 Histologic_Grade_FIGO tumor_grade\n", + "2 Histologic_type history_of_tumor_type\n", + "3 Path_Stage_Primary_Tumor-pT uicc_pathologic_t\n", + "4 Path_Stage_Reg_Lymph_Nodes-pN ajcc_pathologic_n\n", + "5 Clin_Stage_Dist_Mets-cM uicc_pathologic_m\n", + "6 Path_Stage_Dist_Mets-pM uicc_pathologic_m\n", + "7 tumor_Stage-Pathological ajcc_pathologic_stage\n", + "8 FIGO_stage figo_stage\n", + "9 BMI bmi\n", + "10 Age weight\n", + "11 Race race\n", + "12 Ethnicity ethnicity\n", + "13 Gender gender\n", + "14 Tumor_Site tumor_level_prostate\n", + "15 Tumor_Focality tumor_focality\n", + "16 Tumor_Size_cm tumor_width_measurement" + ] + }, + "execution_count": 4, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "column_mappings = bdi.match_schema(dataset, target=\"gdc\", method=\"ct_learning\")\n", + "column_mappings" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": {}, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "Some weights of RobertaModel were not initialized from the model checkpoint at roberta-base and are newly initialized: ['roberta.pooler.dense.bias', 'roberta.pooler.dense.weight']\n", + "You should probably TRAIN this model on a down-stream task to be able to use it for predictions and inference.\n", + "100%|██████████| 1/1 [00:00<00:00, 15.27it/s]\n" + ] + }, + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Table features extracted from 1 columns\n", + "Table features loaded for 734 columns\n", + "Distances (cosine): [0.62180854 0.95828624 0.97060146 1.06355793 1.05457518 0.95031876\n", + " 0.87183141 0.98037726 1.08884842 0.59818588 0.75152265 0.83261097\n", + " 0.80213099 0.77332142 0.87859477 1.16856598 0.83399758 1.10548815\n", + " 0.95137044 1.08006319 0.84199771 1.13298833 1.02036063 1.12404512\n", + " 1.19349639 0.82890662 0.8390033 0.89459161 0.89116058 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1.03081028 1.06579009 1.0865027 0.97509951 1.08919383 1.07088622\n", + " 0.88604682 0.96118678 1.03694739 0.68591457 1.05546631 0.91181083\n", + " 0.98262121 0.94778371 1.11439945 0.97633352 0.964915 1.13867615\n", + " 1.1179955 1.10409814 0.98138727 1.05130809 0.96141391 0.86876938\n", + " 0.95252924 0.91652965 0.75280956 0.90630333 1.02831875 1.03302042\n", + " 0.97673868 1.10415458 1.0962827 1.06599447 0.91712704 1.17343477\n", + " 0.84102231 1.1039787 1.09676816 0.94735573 1.14905006 0.96544546\n", + " 1.01811515 1.14665696 0.83760722 0.97669814 0.7806451 1.06639228\n", + " 1.16535421 1.06304899 1.05594025 1.05733307 1.02019525 1.00608368\n", + " 1.00962811 1.03944518 1.02169401 1.08549306 0.82319006 1.01159241\n", + " 0.94157952 1.07250184 0.94161454 0.9720459 0.65854238 0.81315305\n", + " 1.07131082 0.97547404 0.90212735 1.04709614 0.85534682 1.06743073\n", + " 0.89346954 0.86326391 1.00706814 1.0897298 0.91436948 0.75487052\n", + " 0.75596688 0.94565841 0.95165233 0.93634702 0.96973108 0.83637775\n", + " 0.98326613 0.6558631 0.9933073 1.02725857 1.10585208 0.85823421\n", + " 1.21339282 1.06245269 1.17859525 0.86263995 1.14826524 1.07301848\n", + " 1.24015144 1.36251803 1.08949241 1.11080693 0.96488777 0.94466767\n", + " 1.04388683 1.17506031 0.94300428 0.91997956 0.98400407 0.99623632\n", + " 0.8633667 1.01946885 0.82632191 0.93506847 0.97591708 0.87672968\n", + " 0.71403487 0.97582197 1.0586424 1.02571066 0.86590501 1.1614363\n", + " 0.92650471 0.87893983 0.97773397 0.98611551 0.97761033 1.04815723\n", + " 0.83754575 0.76343419 0.67277256 0.99086506 1.01927109 1.10385477\n", + " 0.96588783 0.86824653]\n", + "Columns: Index(['Country', 'Histologic_Grade_FIGO', 'Histologic_type',\n", + " 'Path_Stage_Primary_Tumor-pT', 'Path_Stage_Reg_Lymph_Nodes-pN',\n", + " 'Clin_Stage_Dist_Mets-cM', 'Path_Stage_Dist_Mets-pM',\n", + " 'tumor_Stage-Pathological', 'FIGO_stage', 'BMI', 'Age', 'Race',\n", + " 'Ethnicity', 'Gender', 'Tumor_Site', 'Tumor_Focality', 'Tumor_Size_cm'],\n", + " dtype='object')\n", + "Topk matches: [{'source_column': 'BMI', 'top_k_columns': [ColumnScore(column_name='average_base_quality', score=0.7367687041662533), ColumnScore(column_name='bmi', score=0.7158004578456193), ColumnScore(column_name='body_surface_area', score=0.6174846726008038), ColumnScore(column_name='intermediate_dimension', score=0.6024270602089243), ColumnScore(column_name='recist_targeted_regions_sum', score=0.5769250770602694), ColumnScore(column_name='longest_dimension', score=0.4945747379045601), ColumnScore(column_name='percent_stromal_cells', score=0.4244262568444388), ColumnScore(column_name='sequencing_date', score=0.4244204325614378), ColumnScore(column_name='spindle_cell_percent', score=0.4189918216712454), ColumnScore(column_name='pmid', score=0.4125009713289247)]}]\n" + ] + }, + { + "data": { + "text/html": [ + "
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" + ], + "text/plain": [ + " source target similarity\n", + "0 BMI average_base_quality 0.736769\n", + "1 BMI bmi 0.715800\n", + "2 BMI body_surface_area 0.617485\n", + "3 BMI intermediate_dimension 0.602427\n", + "4 BMI recist_targeted_regions_sum 0.576925\n", + "5 BMI longest_dimension 0.494575\n", + "6 BMI percent_stromal_cells 0.424426\n", + "7 BMI sequencing_date 0.424420\n", + "8 BMI spindle_cell_percent 0.418992\n", + "9 BMI pmid 0.412501" + ] + }, + "execution_count": 5, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "bdi.top_matches(dataset, columns=[\"BMI\"], target=\"gdc\")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.top_matches(dataset, columns=[\"BMI\"], target=\"gdc\")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.match_schema(dataset[[\"BMI\"]], target=\"gdc\", method=\"ct_learning\")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.top_matches(dataset, columns=[\"Histologic_type\"], target=\"gdc\")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.top_matches(dataset, columns=[\"Histologic_type\"], target=\"gdc\")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.match_schema(dataset[[\"FIGO_stage\", \"BMI\"]], target=\"gdc\", method=\"ct_learning\")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "column_mappings = bdi.match_schema(dataset[columns], target=\"gdc\", method=\"two_phase\")\n", + "column_mappings" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Generating a harmonized table\n", + "\n", + "After discovering a schema mapping, we can generate a new table (DataFrame) using the new column names from the GDC standard vocabulary.\n", + "\n", + "To do so using `bdi-kit`, we can use the function `materialize_mapping()` as follows. Note that the column headers have been renamed to the target schema." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.materialize_mapping(dataset, column_mappings)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Generating a harmonized table with value mappings\n", + "\n", + "`bdi-kit` can also help with translation of the values from the source table to the target standard format.\n", + "\n", + "To this end, `bdi-kit` provides the function `match_values()` that automatically creates value mappings for each string column.\n", + "The output of `match_values()` can be fed to `materialize_mapping()` which materialized the final target using both schema and value mappings." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "# JF: why do we have so many \"None\" in dysplasia_type?\n", + "# and why do we have fewer columns -- the previous dataframe has 10 attributes\n", + "# and this has 7\n", + "value_mappings = bdi.match_values(dataset, column_mapping=column_mappings, target=\"gdc\", method=\"tfidf\")\n", + "bdi.materialize_mapping(dataset, value_mappings)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Verifying the schema mappings\n", + "\n", + "Sometimes the mappings generated automatically may be incorrect or you may to want verify them individually.\n", + "To verify the suggested column mappings, `bdi-kit` offers additional APIs to visualize the data and make any modifications when necessary. \n", + "\n", + "For this example, we will use the column `Histologic_type`. We can start by exploring the columns most similar to `Histologic_type`. \n", + "\n", + "For this, we can use the `top_matches()` function. Here, we notice that `primary_diagnosis` could be a potential target column.\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "hist_type_matches = bdi.top_matches(dataset, columns=[\"Histologic_type\"], sample=true, attrib_desc=true, target=\"gdc\")\n", + "hist_type_matches" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Viewing the column domains\n", + "\n", + "To verify that `primary_diagnosis` is a good target column, we view and compare the domains of each column using the `preview_domain()` function. For the source table, it returns the list of unique values in the source column. For the GDC target, it returns the list of unique valid values that a column can have.\n", + "\n", + "Here we see that the values seem to be related." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.preview_domain(dataset, \"Histologic_type\")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "scrolled": true + }, + "outputs": [], + "source": [ + "bdi.preview_domain(\"gdc\", \"primary_diagnosis\")" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "#### JF: actually, I don't see why this is a correct match, maybe we should have another function that looks for probable matches -- given the values for the first column, return a sample of the second column with similar values. \n", + "Since `primary_diagnosis` looks like a correct match for `Histologic_type`, we can modify the `column_mappings` variable directly." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "column_mappings.loc[column_mappings[\"source\"] == \"Histologic_type\", \"target\"] = \"primary_diagnosis\"\n", + "column_mappings" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Finding correct value mappings\n", + "\n", + "After finding the correct column, we need to find appropriate value mappings. \n", + "Using `preview_value_mappings()`, we can inspect what the possible value mappings for this would look like after the harmonization.\n", + "\n", + "`bdi-kit` implements multiple methods for value mapping discovery, including:\n", + "\n", + " - `edit_distance` - Computes value similarities using Levenstein's edit distance measure.\n", + " - `tfidf` - A method based on tf-idf importance weighting computed over charcter n-grams.\n", + " - `embeddings` - Uses BERT word embeddings to compute \"semantic similarity\" between the values.\n", + "\n", + "To specify a value mapping approach, we can pass the `method` parameter." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.preview_value_mappings(\n", + " dataset, column_mapping=(\"Histologic_type\", \"primary_diagnosis\"), target=\"gdc\", method=\"edit_distance\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.preview_value_mappings(\n", + " dataset, column_mapping=(\"Histologic_type\", \"primary_diagnosis\"), target=\"gdc\", method=\"tfidf\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.preview_value_mappings(\n", + " dataset, column_mapping=(\"Histologic_type\", \"primary_diagnosis\"), target=\"gdc\", method=\"embedding\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "# JF add context - -manual map\n", + "hist_type_vmap = pd.DataFrame(\n", + " columns=[\"source\", \"target\"],\n", + " data=[\n", + " (\"Carcinosarcoma\", \"Carcinosarcoma, NOS\"),\n", + " (\"Clear cell\", \"Clear cell adenocarcinoma, NOS\"),\n", + " (\"Endometrioid\", \"Endometrioid carcinoma\"),\n", + " (\"Serous\", \"Serous cystadenocarcinoma\"),\n", + " ],\n", + ")\n", + "hist_type_vmap" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Verifying multiple value mappings at once\n", + "\n", + "Besides verifying value mappings individually, you can also do it for all column mappings at once." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "mappings = bdi.preview_value_mappings(\n", + " dataset,\n", + " column_mapping=column_mappings,\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + ")\n", + "\n", + "for mapping in mappings:\n", + " print(f\"{mapping['source']} => {mapping['target']}\")\n", + " display(mapping[\"mapping\"])\n", + " print(\"\")" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Fixing remaining value mappings\n", + "\n", + "We need fix a few value mappings:\n", + "- Race\n", + "- Ethnicity\n", + "- Tumor_Site\n", + "\n", + "For race, we need to fix: `nan` -> `merican indian or alaska native`." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "race_vmap = bdi.preview_value_mappings(\n", + " dataset,\n", + " column_mapping=(\"Race\", \"race\"),\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + ")\n", + "race_vmap" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "race_vmap = race_vmap[race_vmap[\"similarity\"] >= 1.0]\n", + "race_vmap" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "For `Ethnicity`, we need to fix: `Not reported` -> `not hispanic or latino`." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "ethinicity_vmap = bdi.preview_value_mappings(\n", + " dataset,\n", + " column_mapping=(\"Ethnicity\", \"ethnicity\"),\n", + " target=\"gdc\",\n", + " method=\"tfidf\",\n", + ")\n", + "ethinicity_vmap\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "ethinicity_vmap = ethinicity_vmap[ethinicity_vmap[\"similarity\"] > 0.9]\n", + "ethinicity_vmap" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "For `Tumor_Site`, given that this dataset is about endometrial cancer, all values must be mapped to \"Endometrium\". So instead of fixing each mapping individually, we will write a custom function that returns \"Endometrium\" regardless of the input value. Later, we will show how to use this function to transform the dataset." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "bdi.preview_value_mappings(\n", + " dataset, column_mapping=(\"Tumor_Site\", \"tissue_or_organ_of_origin\"), target=\"gdc\", method=\"tfidf\"\n", + ")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "# Custom mapping function that will be used to map the values of the 'Tumor_Site' column\n", + "# JF: why does this always return Endometrium?\n", + "def map_tumor_site(source_value):\n", + " return \"Endometrium\"" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "### Combining custom user mappings with suggested mappings\n", + "\n", + "Before generating a final harmonized dataset, we can combine the automatically generated value mappings with the fixed mappings provided by the user. To do so, we use `bdi.update_mappings()` functions, which take a list of mappings (e.g., generated automatically) and a list of \"user-defined mapping overrides\" that will be combined with the first list of mappings and will take precedence whenever they conflict.\n", + "\n", + "In our example below, all mappings specified in the variable `user_mappings` will override the mappings in `value_mappings` generated by the `bdi.match_values()` function." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "from math import ceil\n", + "\n", + "user_mappings = [\n", + " {\n", + " \"source\": \"Tumor_Site\",\n", + " \"target\": \"tissue_or_organ_of_origin\",\n", + " \"mapper\": map_tumor_site,\n", + " },\n", + " {\n", + " \"source\": \"BMI\",\n", + " \"target\": \"bmi\",\n", + " },\n", + " {\n", + " \"source\": \"Age\",\n", + " \"target\": \"days_to_birth\",\n", + " \"mapper\": lambda age: -age * 365.25,\n", + " },\n", + " {\n", + " \"source\": \"Age\",\n", + " \"target\": \"age_at_diagnosis\",\n", + " \"mapper\": lambda age: float(\"nan\") if pd.isnull(age) else ceil(age*365.25),\n", + " },\n", + " {\n", + " \"source\": \"Tumor_Size_cm\",\n", + " \"target\": \"tumor_largest_dimension_diameter\",\n", + " }\n", + "]\n", + "\n", + "value_mappings = bdi.match_values(\n", + " dataset, target=\"gdc\", column_mapping=column_mappings, method=\"tfidf\"\n", + ")\n", + "\n", + "harmonization_spec = bdi.update_mappings(value_mappings, user_mappings)\n" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "Finally, we generate the harmonized dataset, with the user-defined value mappings." + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "# JF: are there still incorrect matches and mappings?\n", + "harmonized_dataset = bdi.materialize_mapping(dataset, harmonization_spec)\n", + "harmonized_dataset" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "For comparison, here is how our original data looked like:" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "original_columns = map(lambda m: m[\"source\"], harmonization_spec)\n", + "dataset[original_columns]" + ] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.10.12" + } + }, + "nbformat": 4, + "nbformat_minor": 2 +}