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SNPTB

A Bioinformatics Pipeline for Analyses of Mycobacterium tuberculosis Whole Genome Sequencing Data

Aditi Gupta

Center for Emerging Pathogens, Rutgers University, Newark NJ 07103

Email: ag1349 [at] njms.rutgers.edu

October 18, 2017

Please see docs for tutorial on how to use SNPTB.

Citation information is in HOW_TO_CITE.

SNPTB is publicly available under the GNU GPL License.

SNPTB contains the following directories:

  • code: contains all scripts
  • software: contains Trimmomatic and FastQC software
  • scheduler: contains script to run the SNPTB pipeline on SLURM job scheduler
  • data: empty directory, option to save raw sequencing data here
  • output: empty directory. When SNPTB is run, a new folder is created in "output" that contains a file with SNP annotation
  • test: contains sample file that shows the format to specify pairs of samples for pairwise SNP identification
  • H37Rv: all files of the reference Mycobacterium tuberculosis genome H37RV needed for running SNPTB