diff --git a/bundlesize.config.json b/bundlesize.config.json
index 799fd205a..d3ea509d5 100644
--- a/bundlesize.config.json
+++ b/bundlesize.config.json
@@ -6,7 +6,7 @@
     },
     {
       "path": "packages/autocomplete-js/dist/umd/index.production.js",
-      "maxSize": "15.5 kB"
+      "maxSize": "15.75 kB"
     },
     {
       "path": "packages/autocomplete-preset-algolia/dist/umd/index.production.js",
diff --git a/packages/autocomplete-core/src/__tests__/getInputProps.test.ts b/packages/autocomplete-core/src/__tests__/getInputProps.test.ts
index a1f5a44e9..0b27d5235 100644
--- a/packages/autocomplete-core/src/__tests__/getInputProps.test.ts
+++ b/packages/autocomplete-core/src/__tests__/getInputProps.test.ts
@@ -1,3 +1,4 @@
+import { waitFor } from '@testing-library/dom';
 import userEvent from '@testing-library/user-event';
 
 import {
@@ -785,6 +786,221 @@ describe('getInputProps', () => {
         userEvent.type(inputElement, '{arrowup}');
         expect(onActive).toHaveBeenCalledTimes(1);
       });
+
+      test('ArrowDown opens the panel when closed with openOnFocus and selects defaultActiveItemId', async () => {
+        const onStateChange = jest.fn();
+        const { inputElement } = createPlayground(createAutocomplete, {
+          onStateChange,
+          openOnFocus: true,
+          getSources() {
+            return [
+              createSource({
+                getItems() {
+                  return [{ label: '1' }];
+                },
+              }),
+            ];
+          },
+        });
+
+        inputElement.focus();
+        await runAllMicroTasks();
+
+        userEvent.type(inputElement, '{esc}{arrowdown}');
+        await runAllMicroTasks();
+
+        await waitFor(() => {
+          expect(onStateChange).toHaveBeenLastCalledWith(
+            expect.objectContaining({
+              state: expect.objectContaining({
+                isOpen: true,
+                activeItemId: null,
+              }),
+            })
+          );
+        });
+      });
+
+      test('ArrowDown opens the panel when closed with a query and selects defaultActiveItemId', async () => {
+        const onStateChange = jest.fn();
+        const { inputElement } = createPlayground(createAutocomplete, {
+          onStateChange,
+          initialState: {
+            query: 'a',
+          },
+          getSources() {
+            return [
+              createSource({
+                getItems() {
+                  return [{ label: '1' }];
+                },
+              }),
+            ];
+          },
+        });
+
+        inputElement.focus();
+        await runAllMicroTasks();
+
+        userEvent.type(inputElement, '{esc}{arrowdown}');
+        await runAllMicroTasks();
+
+        await waitFor(() => {
+          expect(onStateChange).toHaveBeenLastCalledWith(
+            expect.objectContaining({
+              state: expect.objectContaining({
+                isOpen: true,
+                activeItemId: null,
+              }),
+            })
+          );
+        });
+      });
+
+      test('ArrowDown opens the panel when closed with openOnFocus and selects defaultActiveItemId with scrollIntoView', async () => {
+        const onStateChange = jest.fn();
+        const { inputElement, item } = setupTestWithItem({
+          onStateChange,
+          defaultActiveItemId: 0,
+          getSources() {
+            return [
+              createSource({
+                getItems() {
+                  return [{ label: '1' }];
+                },
+              }),
+            ];
+          },
+        });
+        item.scrollIntoView = jest.fn();
+
+        inputElement.focus();
+        await runAllMicroTasks();
+
+        userEvent.type(inputElement, '{esc}{arrowdown}');
+        await runAllMicroTasks();
+
+        await waitFor(() => {
+          expect(onStateChange).toHaveBeenLastCalledWith(
+            expect.objectContaining({
+              state: expect.objectContaining({
+                isOpen: true,
+                activeItemId: 0,
+              }),
+            })
+          );
+
+          expect(item.scrollIntoView).toHaveBeenCalledTimes(1);
+          expect(item.scrollIntoView).toHaveBeenCalledWith(false);
+        });
+      });
+
+      test('ArrowUp opens the panel when closed with openOnFocus and selects the last item', async () => {
+        const onStateChange = jest.fn();
+        const { inputElement } = createPlayground(createAutocomplete, {
+          onStateChange,
+          openOnFocus: true,
+          getSources() {
+            return [
+              createSource({
+                getItems() {
+                  return [{ label: '1' }];
+                },
+              }),
+            ];
+          },
+        });
+
+        inputElement.focus();
+        await runAllMicroTasks();
+
+        userEvent.type(inputElement, '{esc}{arrowup}');
+        await runAllMicroTasks();
+
+        await waitFor(() => {
+          expect(onStateChange).toHaveBeenLastCalledWith(
+            expect.objectContaining({
+              state: expect.objectContaining({
+                isOpen: true,
+                activeItemId: 0,
+              }),
+            })
+          );
+        });
+      });
+
+      test('ArrowUp opens the panel when closed with a query and selects the last item', async () => {
+        const onStateChange = jest.fn();
+        const { inputElement } = createPlayground(createAutocomplete, {
+          onStateChange,
+          initialState: {
+            query: 'a',
+          },
+          getSources() {
+            return [
+              createSource({
+                getItems() {
+                  return [{ label: '1' }];
+                },
+              }),
+            ];
+          },
+        });
+
+        inputElement.focus();
+        await runAllMicroTasks();
+
+        userEvent.type(inputElement, '{esc}{arrowup}');
+        await runAllMicroTasks();
+
+        await waitFor(() => {
+          expect(onStateChange).toHaveBeenLastCalledWith(
+            expect.objectContaining({
+              state: expect.objectContaining({
+                isOpen: true,
+                activeItemId: 0,
+              }),
+            })
+          );
+        });
+      });
+
+      test('ArrowUp opens the panel when closed with openOnFocus and selects the last item with scrollIntoView', async () => {
+        const onStateChange = jest.fn();
+        const { inputElement, item } = setupTestWithItem({
+          onStateChange,
+          getSources() {
+            return [
+              createSource({
+                getItems() {
+                  return [{ label: '1' }];
+                },
+              }),
+            ];
+          },
+        });
+        item.scrollIntoView = jest.fn();
+
+        inputElement.focus();
+        await runAllMicroTasks();
+
+        userEvent.type(inputElement, '{esc}{arrowup}');
+        await runAllMicroTasks();
+
+        await waitFor(() => {
+          expect(onStateChange).toHaveBeenLastCalledWith(
+            expect.objectContaining({
+              state: expect.objectContaining({
+                isOpen: true,
+                activeItemId: 0,
+              }),
+            })
+          );
+
+          expect(item.scrollIntoView).toHaveBeenCalledTimes(1);
+          expect(item.scrollIntoView).toHaveBeenCalledWith(false);
+        });
+      });
     });
 
     describe('Escape', () => {
@@ -860,6 +1076,7 @@ describe('getInputProps', () => {
             state: expect.objectContaining({
               query: '',
               status: 'idle',
+              activeItemId: null,
               collections: [],
             }),
           })
diff --git a/packages/autocomplete-core/src/onKeyDown.ts b/packages/autocomplete-core/src/onKeyDown.ts
index 333b98860..ee37a463d 100644
--- a/packages/autocomplete-core/src/onKeyDown.ts
+++ b/packages/autocomplete-core/src/onKeyDown.ts
@@ -1,5 +1,6 @@
 import { onInput } from './onInput';
 import {
+  ActionType,
   AutocompleteScopeApi,
   AutocompleteStore,
   BaseItem,
@@ -22,39 +23,74 @@ export function onKeyDown<TItem extends BaseItem>({
   ...setters
 }: OnKeyDownOptions<TItem>): void {
   if (event.key === 'ArrowUp' || event.key === 'ArrowDown') {
-    // Default browser behavior changes the caret placement on ArrowUp and
-    // Arrow down.
-    event.preventDefault();
+    // eslint-disable-next-line no-inner-declarations
+    function triggerScrollIntoView() {
+      const nodeItem = props.environment.document.getElementById(
+        `${props.id}-item-${store.getState().activeItemId}`
+      );
 
-    store.dispatch(event.key, null);
+      if (nodeItem) {
+        if ((nodeItem as any).scrollIntoViewIfNeeded) {
+          (nodeItem as any).scrollIntoViewIfNeeded(false);
+        } else {
+          nodeItem.scrollIntoView(false);
+        }
+      }
+    }
+
+    // eslint-disable-next-line no-inner-declarations
+    function triggerOnActive() {
+      const highlightedItem = getActiveItem(store.getState());
 
-    const nodeItem = props.environment.document.getElementById(
-      `${props.id}-item-${store.getState().activeItemId}`
-    );
+      if (store.getState().activeItemId !== null && highlightedItem) {
+        const { item, itemInputValue, itemUrl, source } = highlightedItem;
 
-    if (nodeItem) {
-      if ((nodeItem as any).scrollIntoViewIfNeeded) {
-        (nodeItem as any).scrollIntoViewIfNeeded(false);
-      } else {
-        nodeItem.scrollIntoView(false);
+        source.onActive({
+          event,
+          item,
+          itemInputValue,
+          itemUrl,
+          refresh,
+          source,
+          state: store.getState(),
+          ...setters,
+        });
       }
     }
 
-    const highlightedItem = getActiveItem(store.getState());
-
-    if (store.getState().activeItemId !== null && highlightedItem) {
-      const { item, itemInputValue, itemUrl, source } = highlightedItem;
+    // Default browser behavior changes the caret placement on ArrowUp and
+    // ArrowDown.
+    event.preventDefault();
 
-      source.onActive({
+    // When re-opening the panel, we need to split the logic to keep the actions
+    // synchronized as `onInput` returns a promise.
+    if (
+      store.getState().isOpen === false &&
+      (props.openOnFocus || Boolean(store.getState().query))
+    ) {
+      onInput({
         event,
-        item,
-        itemInputValue,
-        itemUrl,
+        props,
+        query: store.getState().query,
         refresh,
-        source,
-        state: store.getState(),
+        store,
         ...setters,
+      }).then(() => {
+        store.dispatch(event.key as ActionType, {
+          nextActiveItemId: props.defaultActiveItemId,
+        });
+
+        triggerOnActive();
+        // Since we rely on the DOM, we need to wait for all the micro tasks to
+        // finish (which include re-opening the panel) to make sure all the
+        // elements are available.
+        setTimeout(triggerScrollIntoView, 0);
       });
+    } else {
+      store.dispatch(event.key, {});
+
+      triggerOnActive();
+      triggerScrollIntoView();
     }
   } else if (event.key === 'Escape') {
     // This prevents the default browser behavior on `input[type="search"]`
diff --git a/packages/autocomplete-core/src/stateReducer.ts b/packages/autocomplete-core/src/stateReducer.ts
index debe7fc08..ced4cfea2 100644
--- a/packages/autocomplete-core/src/stateReducer.ts
+++ b/packages/autocomplete-core/src/stateReducer.ts
@@ -55,12 +55,14 @@ export const stateReducer: Reducer = (state, action) => {
     case 'ArrowDown': {
       const nextState = {
         ...state,
-        activeItemId: getNextActiveItemId(
-          1,
-          state.activeItemId,
-          getItemsCount(state),
-          action.props.defaultActiveItemId
-        ),
+        activeItemId: action.payload.hasOwnProperty('nextActiveItemId')
+          ? action.payload.nextActiveItemId
+          : getNextActiveItemId(
+              1,
+              state.activeItemId,
+              getItemsCount(state),
+              action.props.defaultActiveItemId
+            ),
       };
 
       return {
@@ -90,6 +92,7 @@ export const stateReducer: Reducer = (state, action) => {
       if (state.isOpen) {
         return {
           ...state,
+          activeItemId: null,
           isOpen: false,
           completion: null,
         };
@@ -97,6 +100,7 @@ export const stateReducer: Reducer = (state, action) => {
 
       return {
         ...state,
+        activeItemId: null,
         query: '',
         status: 'idle',
         collections: [],
diff --git a/packages/autocomplete-core/src/types/AutocompleteStore.ts b/packages/autocomplete-core/src/types/AutocompleteStore.ts
index 506ea5595..7334a4a35 100644
--- a/packages/autocomplete-core/src/types/AutocompleteStore.ts
+++ b/packages/autocomplete-core/src/types/AutocompleteStore.ts
@@ -18,7 +18,7 @@ type Action<TItem extends BaseItem, TPayload> = {
   payload: TPayload;
 };
 
-type ActionType =
+export type ActionType =
   | 'setActiveItemId'
   | 'setQuery'
   | 'setCollections'