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Bandsize note for ITS? #35

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hhollandmoritz opened this issue May 16, 2019 · 0 comments
Open

Bandsize note for ITS? #35

hhollandmoritz opened this issue May 16, 2019 · 0 comments
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enhancement New feature or request

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@hhollandmoritz
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On re-reading the methods in the DADA2 paper, I notice they recommend a different band size for ITS sequences. It might be nice to put a note about it in the pipeline.

According to the DADA2 github issue 195:

We currently recommend BAND_SIZE=32 for ITS data.

In our testing the default (BAND_SIZE=16) has worked just fine, but because indel rates are so much higher in ITS and we don't have as much experience with it, the larger band size is prudent. The only cost is that run-time will be about 1.5x longer.
@hhollandmoritz hhollandmoritz added the enhancement New feature or request label May 16, 2019
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