diff --git a/src/runtime/contrib/tflite/tflite_runtime.cc b/src/runtime/contrib/tflite/tflite_runtime.cc
index 53d7754be9469..a40fd04959f88 100644
--- a/src/runtime/contrib/tflite/tflite_runtime.cc
+++ b/src/runtime/contrib/tflite/tflite_runtime.cc
@@ -93,8 +93,12 @@ DataType TfLiteDType2TVMDType(TfLiteType dtype) {
 void TFLiteRuntime::Init(const std::string& tflite_model_bytes, TVMContext ctx) {
   const char* buffer = tflite_model_bytes.c_str();
   size_t buffer_size = tflite_model_bytes.size();
+  // The buffer used to construct the model must be kept alive for
+  // dependent interpreters to be used.
+  flatBuffersBuffer_ = std::unique_ptr<char[]>(new char[buffer_size]);
+  std::memcpy(flatBuffersBuffer_.get(), buffer, buffer_size);
   std::unique_ptr<tflite::FlatBufferModel> model =
-      tflite::FlatBufferModel::BuildFromBuffer(buffer, buffer_size);
+      tflite::FlatBufferModel::BuildFromBuffer(flatBuffersBuffer_.get(), buffer_size);
   tflite::ops::builtin::BuiltinOpResolver resolver;
   // Build interpreter
   TfLiteStatus status = tflite::InterpreterBuilder(*model, resolver)(&interpreter_);
diff --git a/src/runtime/contrib/tflite/tflite_runtime.h b/src/runtime/contrib/tflite/tflite_runtime.h
index f61f6ee37e0b9..e4d231c03fb14 100644
--- a/src/runtime/contrib/tflite/tflite_runtime.h
+++ b/src/runtime/contrib/tflite/tflite_runtime.h
@@ -93,6 +93,8 @@ class TFLiteRuntime : public ModuleNode {
    */
   NDArray GetOutput(int index) const;
 
+  // Buffer backing the interpreter's model
+  std::unique_ptr<char[]> flatBuffersBuffer_;
   // TFLite interpreter
   std::unique_ptr<tflite::Interpreter> interpreter_;
   // TVM context