diff --git a/easyconfigs/r/RootPainter/RootPainter-0.2.27.0-foss-2022a-CUDA-11.7.0.eb b/easyconfigs/r/RootPainter/RootPainter-0.2.27.0-foss-2022a-CUDA-11.7.0.eb
new file mode 100644
index 00000000..fdcb5d59
--- /dev/null
+++ b/easyconfigs/r/RootPainter/RootPainter-0.2.27.0-foss-2022a-CUDA-11.7.0.eb
@@ -0,0 +1,37 @@
+easyblock = "PythonBundle"
+
+name = 'RootPainter'
+version = '0.2.27.0'
+versionsuffix = '-CUDA-%(cudaver)s'
+
+homepage = 'https://github.com/healpy/healpy'
+description = """RootPainter is a GUI-based software tool for the rapid training of deep neural networks for use in
+ biological image analysis. RootPainter uses a client-server architecture, allowing users with a typical laptop to
+ utilise a GPU on a more computationally powerful server."""
+
+toolchain = {'name': 'foss', 'version': '2022a'}
+toolchainopts = {'pic': True}
+
+dependencies = [
+    ('Python', '3.10.4'),
+    ('CUDA', '11.7.0', '', SYSTEM),
+    ('SciPy-bundle', '2022.05'),
+    ('scikit-image', '0.19.3'),
+    ('Pillow', '9.1.1'),
+    ('PyTorch', '2.0.1', versionsuffix),
+    ('torchvision', '0.15.2', versionsuffix),
+]
+
+use_pip = True
+sanity_pip_check = True
+
+exts_list = [
+    ('imagecodecs', '2023.3.16', {
+        'source_tmpl': '%(name)s-%(version)s-cp310-cp310-manylinux_2_17_x86_64.manylinux2014_x86_64.whl'
+    }),
+    ('root_painter_trainer', version, {
+        'patches': ['python-deps.patch']
+    }),
+]
+
+moduleclass = 'bio'
diff --git a/easyconfigs/r/RootPainter/python-deps.patch b/easyconfigs/r/RootPainter/python-deps.patch
new file mode 100644
index 00000000..1c4ae91c
--- /dev/null
+++ b/easyconfigs/r/RootPainter/python-deps.patch
@@ -0,0 +1,23 @@
+--- setup.py.old	2023-06-26 14:24:17.129957315 +0100
++++ setup.py	2023-06-26 14:25:00.078147644 +0100
+@@ -22,13 +22,13 @@
+     ]
+   },
+   install_requires=[
+-    "scikit-image==0.19.3",
+-    "numpy==1.24.2",
+-    "scipy==1.10.0",
+-    "Pillow==9.3.0",
+-    "imagecodecs==2021.8.26",
+-    "torch==1.13.1",
+-    "torchvision==0.14.1"
++    "scikit-image>=0.19.3",
++    "numpy>=1.22.3",
++    "scipy>=1.8.1",
++    "Pillow>=9.1.0",
++    "imagecodecs>=2021.8.26",
++    "torch>=1.13.1",
++    "torchvision>=0.14.1"
+   ],
+   classifiers=[
+     'Intended Audience :: Developers',