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DESCRIPTION
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DESCRIPTION
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Package: EffToxDesign
Type: Package
Title: EffTox Phase I/II Clinical Trial Design
Version: 0.4
Date: 2020-02-28
Authors@R: c(person("Brian J", "Smith", email = "[email protected]", role = c("aut", "cre")),
person("Kristian", "Brock", role = c("aut")),
person("Brian J", "Smith", role = "cph"))
Maintainer: Brian J Smith <[email protected]>
Description: An adaptive Bayesian design for dose-finding in combined phase I/II clinical trials based on trade-offs between the probabilities of treatment efficacy and toxicity, as developed by Thall and Cook (2004, Biometrics 60, 684-693).
License: GPL-3
Depends:
R (>= 3.0.2),
Rcpp (>= 0.12.8),
methods (>= 3.3.2)
Imports:
bcrm,
clinfun,
coda,
foreach,
ggplot2,
gtools,
logitnorm,
magrittr,
R6,
rstan (>= 2.12.1),
truncnorm
LinkingTo:
StanHeaders (>= 2.12.0.1),
rstan (>= 2.12.1),
BH (>= 1.62.0.1),
Rcpp (>= 0.12.8),
RcppEigen (>= 0.3.2.9.0)
Suggests:
knitr,
rmarkdown
Biarch: true
RoxygenNote: 6.0.1