diff --git a/end-to-end-test/remote/screenshots/reference/tcga_pancancer_atlas_page_element_chrome_1600x1000.png b/end-to-end-test/remote/screenshots/reference/tcga_pancancer_atlas_page_element_chrome_1600x1000.png
index e379efe59d9..352c228e105 100644
Binary files a/end-to-end-test/remote/screenshots/reference/tcga_pancancer_atlas_page_element_chrome_1600x1000.png and b/end-to-end-test/remote/screenshots/reference/tcga_pancancer_atlas_page_element_chrome_1600x1000.png differ
diff --git a/end-to-end-test/remote/specs/core/comparisonTab.screenshot.spec.js b/end-to-end-test/remote/specs/core/comparisonTab.screenshot.spec.js
index e455771a63b..6fca1926f93 100644
--- a/end-to-end-test/remote/specs/core/comparisonTab.screenshot.spec.js
+++ b/end-to-end-test/remote/specs/core/comparisonTab.screenshot.spec.js
@@ -367,49 +367,6 @@ describe('results view comparison tab screenshot tests', function() {
             );
             assertScreenShotMatch(res);
         });
-
-        it('results view comparison tab microbiome signature tab several groups', function() {
-            goToUrlAndSetLocalStorage(
-                `${CBIOPORTAL_URL}/results/comparison?Action=Submit&RPPA_SCORE_THRESHOLD=2.0&Z_SCORE_THRESHOLD=2.0&cancer_study_list=blca_tcga_pan_can_atlas_2018&case_set_id=blca_tcga_pan_can_atlas_2018_cnaseq&comparison_selectedGroups=%5B"CDKN2A"%2C"MDM2"%2C"MDM4"%5D&comparison_subtab=generic_assay_microbiome_signature&data_priority=0&gene_list=CDKN2A%2520MDM2%2520MDM4&geneset_list=%20&genetic_profile_ids_PROFILE_COPY_NUMBER_ALTERATION=blca_tcga_pan_can_atlas_2018_gistic&genetic_profile_ids_PROFILE_MUTATION_EXTENDED=blca_tcga_pan_can_atlas_2018_mutations&profileFilter=0&tab_index=tab_visualize`
-            );
-            $(
-                'div[data-test="GroupComparisonGenericAssayEnrichments"]'
-            ).waitForDisplayed({ timeout: 10000 });
-            $('b=Polyomavirus').waitForDisplayed({ timeout: 10000 });
-            $('b=Polyomavirus').click();
-            $('div[data-test="MiniBoxPlot"]').waitForDisplayed({
-                timeout: 20000,
-            });
-            $('body').moveTo({ xOffset: 0, yOffset: 0 });
-            var res = browser.checkElement(
-                '.msk-tab:not(.hiddenByPosition)',
-                '',
-                {
-                    hide: ['.qtip'],
-                }
-            );
-            assertScreenShotMatch(res);
-        });
-
-        it('results view comparison tab microbiome signature tab two groups', function() {
-            // deselect a group
-            $('button[data-test="groupSelectorButtonMDM4"]').click();
-
-            $(
-                'div[data-test="GroupComparisonGenericAssayEnrichments"]'
-            ).waitForDisplayed({ timeout: 10000 });
-            $('b=Wolbachia').waitForDisplayed({ timeout: 10000 });
-            $('b=Wolbachia').click();
-            $('body').moveTo({ xOffset: 0, yOffset: 0 });
-            var res = browser.checkElement(
-                '.msk-tab:not(.hiddenByPosition)',
-                '',
-                {
-                    hide: ['.qtip'],
-                }
-            );
-            assertScreenShotMatch(res);
-        });
     });
 
     describe('delete group from session', function() {
diff --git a/end-to-end-test/remote/specs/core/groupComparison.screenshot.spec.js b/end-to-end-test/remote/specs/core/groupComparison.screenshot.spec.js
index 91841df3453..a58f4bbc32c 100644
--- a/end-to-end-test/remote/specs/core/groupComparison.screenshot.spec.js
+++ b/end-to-end-test/remote/specs/core/groupComparison.screenshot.spec.js
@@ -385,54 +385,6 @@ describe('group comparison page screenshot tests', function() {
             assertScreenShotMatch(res);
         });
 
-        it('group comparison page microbiome signature tab several groups', function() {
-            // use study blca_tcga_pan_can_atlas_2018 for microbiome signature tests
-            goToUrlAndSetLocalStorage(
-                `${CBIOPORTAL_URL}/comparison/generic_assay_microbiome_signature?sessionId=5d63f222e4b0d777deb05c78&unselectedGroups=%5B%22NA%22%5D`
-            );
-            $(
-                'div[data-test="GroupComparisonGenericAssayEnrichments"]'
-            ).waitForDisplayed({ timeout: 10000 });
-            $(
-                'div[data-test="GroupComparisonGenericAssayEnrichments"]'
-            ).waitForDisplayed({ timeout: 10000 });
-            $('b=Collimonas').waitForDisplayed({ timeout: 10000 });
-            $('b=Collimonas').click();
-            $('div[data-test="MiniBoxPlot"]').waitForDisplayed({
-                timeout: 20000,
-            });
-            $('body').moveTo({ xOffset: 0, yOffset: 0 });
-            var res = browser.checkElement(
-                '.msk-tab:not(.hiddenByPosition)',
-                '',
-                {
-                    hide: ['.qtip'],
-                }
-            );
-            assertScreenShotMatch(res);
-        });
-
-        it('group comparison page microbiome signature tab two groups', function() {
-            // use study blca_tcga_pan_can_atlas_2018 for microbiome signature tests
-            goToUrlAndSetLocalStorage(
-                `${CBIOPORTAL_URL}/comparison/generic_assay_microbiome_signature?sessionId=5d63f222e4b0d777deb05c78&unselectedGroups=%5B%22NA%22%2C%22White%22%5D`
-            );
-            $(
-                'div[data-test="GroupComparisonGenericAssayEnrichments"]'
-            ).waitForDisplayed({ timeout: 10000 });
-            $('b=Lawsonia').waitForDisplayed({ timeout: 10000 });
-            $('b=Lawsonia').click();
-            $('body').moveTo({ xOffset: 0, yOffset: 0 });
-            var res = browser.checkElement(
-                '.msk-tab:not(.hiddenByPosition)',
-                '',
-                {
-                    hide: ['.qtip'],
-                }
-            );
-            assertScreenShotMatch(res);
-        });
-
         it('group comparison page mutations tab two groups', function() {
             goToUrlAndSetLocalStorage(
                 `${CBIOPORTAL_URL}/comparison/mutations?sessionId=5cf89323e4b0ab413787436c&selectedGene=AR`
diff --git a/end-to-end-test/remote/specs/core/studyview.spec.js b/end-to-end-test/remote/specs/core/studyview.spec.js
index 6bc3125575a..ae24a5aed7c 100644
--- a/end-to-end-test/remote/specs/core/studyview.spec.js
+++ b/end-to-end-test/remote/specs/core/studyview.spec.js
@@ -725,7 +725,9 @@ describe('submit genes to results view query', () => {
             goToUrlAndSetLocalStorage(url);
             waitForNetworkQuiet();
         });
-        it('generic assay chart should be added in the summary tab', function() {
+        // this relies on the micbiobiome signature generic assay
+        // which no longer exists (data retracted)
+        it.skip('generic assay chart should be added in the summary tab', function() {
             this.retries(0);
             browser.waitUntil(
                 () =>
@@ -736,10 +738,15 @@ describe('submit genes to results view query', () => {
             );
             $(ADD_CHART_BUTTON).click();
 
+            browser.debug();
+
             // Change to GENERIC ASSAY tab
             $(ADD_CHART_GENERIC_ASSAY_TAB).waitForDisplayed({
                 timeout: WAIT_FOR_VISIBLE_TIMEOUT,
             });
+
+            browser.debug();
+
             $(ADD_CHART_GENERIC_ASSAY_TAB).click();
 
             // wait for generic assay data loading complete