diff --git a/src/main/java/org/cbioportal/persistence/CacheEnabledConfig.java b/src/main/java/org/cbioportal/persistence/CacheEnabledConfig.java
index af04bac392c..45b22f5bbf4 100644
--- a/src/main/java/org/cbioportal/persistence/CacheEnabledConfig.java
+++ b/src/main/java/org/cbioportal/persistence/CacheEnabledConfig.java
@@ -16,8 +16,11 @@ public class CacheEnabledConfig {
 
     @Value("${persistence.cache_type:no-cache}")
     private String cacheType;
+    @Value("${persistence.cache_type_clickhouse:no-cache}")
+    private String cacheTypeClickhouse;
 
     private boolean enabled;
+    private boolean enabledClickhouse;
     
     public static final String EHCACHE_DISK = "ehcache-disk";
     public static final String EHCACHE_HEAP = "ehcache-heap";
@@ -30,6 +33,8 @@ public class CacheEnabledConfig {
     public void init() {
         this.enabled = enableCache(cacheType);
         LOG.info("Cache is enabled: " + this.enabled);
+        this.enabledClickhouse = enableCache(cacheTypeClickhouse);
+        LOG.info("Cache is enabled for clickhouse: " + this.enabledClickhouse);
     }
 
     public static boolean enableCache(String cacheType) {
@@ -53,4 +58,16 @@ public boolean isEnabled() {
         return enabled;
     }
 
+    public String getEnabledClickhouse() {
+        if (enabledClickhouse) {
+            return "true";
+        } else {
+            return "false";
+        }
+    }
+
+    public boolean isEnabledClickhouse() {
+        return enabledClickhouse;
+    }
+
 }
diff --git a/src/main/java/org/cbioportal/persistence/cachemaputil/SpringManagedCacheMapUtil.java b/src/main/java/org/cbioportal/persistence/cachemaputil/SpringManagedCacheMapUtil.java
index e58f04b6cf5..c492b2400b0 100644
--- a/src/main/java/org/cbioportal/persistence/cachemaputil/SpringManagedCacheMapUtil.java
+++ b/src/main/java/org/cbioportal/persistence/cachemaputil/SpringManagedCacheMapUtil.java
@@ -57,6 +57,8 @@ public class SpringManagedCacheMapUtil implements CacheMapUtil {
 
     @Value("${persistence.cache_type:no-cache}")
     private String cacheType;
+    @Value("${persistence.cache_type_clickhouse:no-cache}")
+    private String cacheTypeClickhouse;
     
     @Value("${cache.cache-map-utils.spring-managed}")
     private boolean springManagedCacheMapUtils;
@@ -67,7 +69,7 @@ public class SpringManagedCacheMapUtil implements CacheMapUtil {
     @PostConstruct
     public void init() {
         // Make sure the user does not have a conflicting configuration. Explode if there is.
-        if (cacheType.equals("no-cache") && springManagedCacheMapUtils) {
+        if (cacheType.equals("no-cache") && cacheTypeClickhouse.equals("no-cache") && springManagedCacheMapUtils) {
             throw new RuntimeException("cache.cache-map-utils.spring-managed property is set to 'true' but the portal is not " +
                 "configured with a cache-implementation (persistence.cache_type property is 'no-cache'). Please set to 'false'" +
                 " or configure the cache.");
diff --git a/src/main/java/org/cbioportal/persistence/config/RedisConfig.java b/src/main/java/org/cbioportal/persistence/config/RedisConfig.java
index 2da81e8787c..99c225a33bd 100644
--- a/src/main/java/org/cbioportal/persistence/config/RedisConfig.java
+++ b/src/main/java/org/cbioportal/persistence/config/RedisConfig.java
@@ -3,8 +3,8 @@
 import org.cbioportal.persistence.util.CustomKeyGenerator;
 import org.cbioportal.persistence.util.CustomRedisCachingProvider;
 import org.cbioportal.persistence.util.LoggingCacheErrorHandler;
-import org.cbioportal.utils.config.annotation.ConditionalOnProperty;
 import org.springframework.beans.factory.annotation.Value;
+import org.springframework.boot.autoconfigure.condition.ConditionalOnExpression;
 import org.springframework.cache.CacheManager;
 import org.springframework.cache.annotation.CachingConfigurerSupport;
 import org.springframework.cache.annotation.EnableCaching;
@@ -18,7 +18,9 @@
 
 @Configuration
 @EnableCaching
-@ConditionalOnProperty(name = "persistence.cache_type", havingValue = {"redis"})
+@ConditionalOnExpression(
+    "#{environment['persistence.cache_type'] == 'redis' or environment['persistence.cache_type_clickhouse'] == 'redis'}"
+)
 public class RedisConfig extends CachingConfigurerSupport {
     
     @Value("${redis.name:cbioportal}")
diff --git a/src/main/java/org/cbioportal/persistence/util/CustomKeyGenerator.java b/src/main/java/org/cbioportal/persistence/util/CustomKeyGenerator.java
index 1ae254cef05..948d5d344c5 100644
--- a/src/main/java/org/cbioportal/persistence/util/CustomKeyGenerator.java
+++ b/src/main/java/org/cbioportal/persistence/util/CustomKeyGenerator.java
@@ -64,7 +64,7 @@ public class CustomKeyGenerator implements KeyGenerator {
     private static final Logger LOG = LoggerFactory.getLogger(CustomKeyGenerator.class);
 
     public Object generate(Object target, Method method, Object... params) {
-        if (!cacheEnabledConfig.isEnabled()) {
+        if (!cacheEnabledConfig.isEnabled() && !cacheEnabledConfig.isEnabledClickhouse()) {
             return "";
         }
         String key = target.getClass().getSimpleName() + CACHE_KEY_PARAM_DELIMITER
diff --git a/src/main/java/org/cbioportal/persistence/util/RedisCacheUtils.java b/src/main/java/org/cbioportal/persistence/util/RedisCacheUtils.java
index 67639dc75b5..ec5579c544d 100644
--- a/src/main/java/org/cbioportal/persistence/util/RedisCacheUtils.java
+++ b/src/main/java/org/cbioportal/persistence/util/RedisCacheUtils.java
@@ -3,9 +3,9 @@
 import static org.cbioportal.persistence.util.CustomRedisCache.DELIMITER;
 
 
-import org.cbioportal.utils.config.annotation.ConditionalOnProperty;
 import org.redisson.api.RedissonClient;
 import org.springframework.beans.factory.annotation.Autowired;
+import org.springframework.boot.autoconfigure.condition.ConditionalOnExpression;
 import org.springframework.cache.Cache;
 import org.springframework.cache.CacheManager;
 import org.springframework.stereotype.Component;
@@ -14,7 +14,9 @@
 import java.util.stream.Collectors;
 
 @Component
-@ConditionalOnProperty(name = "persistence.cache_type", havingValue = "redis")
+@ConditionalOnExpression(
+    "#{environment['persistence.cache_type'] == 'redis' or environment['persistence.cache_type_clickhouse'] == 'redis'}"
+)
 public class RedisCacheUtils implements CacheUtils {
 
     @Autowired
diff --git a/src/main/java/org/cbioportal/service/impl/ClinicalDataDensityPlotServiceImpl.java b/src/main/java/org/cbioportal/service/impl/ClinicalDataDensityPlotServiceImpl.java
index 0883ff6491f..b6e4a55e679 100644
--- a/src/main/java/org/cbioportal/service/impl/ClinicalDataDensityPlotServiceImpl.java
+++ b/src/main/java/org/cbioportal/service/impl/ClinicalDataDensityPlotServiceImpl.java
@@ -25,7 +25,7 @@ public class ClinicalDataDensityPlotServiceImpl implements ClinicalDataDensityPl
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public DensityPlotData getDensityPlotData(List<ClinicalData> sampleClinicalData, DensityPlotParameters densityPlotParameters) {
diff --git a/src/main/java/org/cbioportal/service/impl/RedisCacheStatisticsServiceImpl.java b/src/main/java/org/cbioportal/service/impl/RedisCacheStatisticsServiceImpl.java
index e6abafc1cc5..ef8e447355a 100644
--- a/src/main/java/org/cbioportal/service/impl/RedisCacheStatisticsServiceImpl.java
+++ b/src/main/java/org/cbioportal/service/impl/RedisCacheStatisticsServiceImpl.java
@@ -7,6 +7,7 @@
 import org.cbioportal.utils.config.annotation.ConditionalOnProperty;
 import org.springframework.beans.factory.annotation.Autowired;
 import org.springframework.beans.factory.annotation.Value;
+import org.springframework.boot.autoconfigure.condition.ConditionalOnExpression;
 import org.springframework.cache.Cache;
 import org.springframework.cache.CacheManager;
 import org.springframework.security.access.AccessDeniedException;
@@ -19,7 +20,9 @@
 import java.util.stream.Collectors;
 
 @Service
-@ConditionalOnProperty(name = "persistence.cache_type", havingValue = {"redis"})
+@ConditionalOnExpression(
+    "#{environment['persistence.cache_type'] == 'redis' or environment['persistence.cache_type_clickhouse'] == 'redis'}"
+)
 public class RedisCacheStatisticsServiceImpl implements CacheStatisticsService {
 
     @Autowired
diff --git a/src/main/java/org/cbioportal/service/impl/StudyViewColumnarServiceImpl.java b/src/main/java/org/cbioportal/service/impl/StudyViewColumnarServiceImpl.java
index 8a4ca8ccdfd..26e988f73cb 100644
--- a/src/main/java/org/cbioportal/service/impl/StudyViewColumnarServiceImpl.java
+++ b/src/main/java/org/cbioportal/service/impl/StudyViewColumnarServiceImpl.java
@@ -52,10 +52,10 @@ public StudyViewColumnarServiceImpl(StudyViewRepository studyViewRepository, Alt
         this.customDataFilterUtil = customDataFilterUtil;
     }
 
-    // should  condition = "@cacheEnabledConfig.getEnabled() && #singleStudyUnfiltered" 
+    // should  condition = "@cacheEnabledConfig.getEnabledClickhouse() && #singleStudyUnfiltered" 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<Sample> getFilteredSamples(StudyViewFilter studyViewFilter) {
@@ -65,7 +65,7 @@ public List<Sample> getFilteredSamples(StudyViewFilter studyViewFilter) {
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<AlterationCountByGene> getMutatedGenes(StudyViewFilter studyViewFilter) throws StudyNotFoundException {
@@ -74,7 +74,7 @@ public List<AlterationCountByGene> getMutatedGenes(StudyViewFilter studyViewFilt
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<GenomicDataCount> getMolecularProfileSampleCounts(StudyViewFilter studyViewFilter) {
@@ -83,7 +83,7 @@ public List<GenomicDataCount> getMolecularProfileSampleCounts(StudyViewFilter st
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<ClinicalEventTypeCount> getClinicalEventTypeCounts(StudyViewFilter studyViewFilter) {
@@ -92,7 +92,7 @@ public List<ClinicalEventTypeCount> getClinicalEventTypeCounts(StudyViewFilter s
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public PatientTreatmentReport getPatientTreatmentReport(StudyViewFilter studyViewFilter) {
@@ -101,7 +101,7 @@ public PatientTreatmentReport getPatientTreatmentReport(StudyViewFilter studyVie
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public SampleTreatmentReport getSampleTreatmentReport(StudyViewFilter studyViewFilter) {
@@ -110,7 +110,7 @@ public SampleTreatmentReport getSampleTreatmentReport(StudyViewFilter studyViewF
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<ClinicalDataCountItem> getGenomicDataBinCounts(StudyViewFilter studyViewFilter, List<GenomicDataBinFilter> genomicDataBinFilters) {
@@ -119,7 +119,7 @@ public List<ClinicalDataCountItem> getGenomicDataBinCounts(StudyViewFilter study
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<ClinicalDataCountItem> getGenericAssayDataBinCounts(StudyViewFilter studyViewFilter, List<GenericAssayDataBinFilter> genericAssayDataBinFilters) {
@@ -132,7 +132,7 @@ public List<CopyNumberCountByGene> getCnaGenes(StudyViewFilter studyViewFilter)
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<AlterationCountByGene> getStructuralVariantGenes(StudyViewFilter studyViewFilter) throws StudyNotFoundException {
@@ -141,7 +141,7 @@ public List<AlterationCountByGene> getStructuralVariantGenes(StudyViewFilter stu
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public Map<String, ClinicalDataType> getClinicalAttributeDatatypeMap() {
@@ -150,7 +150,7 @@ public Map<String, ClinicalDataType> getClinicalAttributeDatatypeMap() {
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<ClinicalDataCountItem> getClinicalDataCounts(StudyViewFilter studyViewFilter, List<String> filteredAttributes) {
@@ -169,7 +169,7 @@ public List<ClinicalDataCountItem> getClinicalDataCounts(StudyViewFilter studyVi
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<CaseListDataCount> getCaseListDataCounts(StudyViewFilter studyViewFilter) {
@@ -181,7 +181,7 @@ public List<CaseListDataCount> getCaseListDataCounts(StudyViewFilter studyViewFi
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<ClinicalData> getPatientClinicalData(StudyViewFilter studyViewFilter, List<String> attributeIds) {
@@ -190,7 +190,7 @@ public List<ClinicalData> getPatientClinicalData(StudyViewFilter studyViewFilter
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<ClinicalData> getSampleClinicalData(StudyViewFilter studyViewFilter, List<String> attributeIds) {
@@ -199,7 +199,7 @@ public List<ClinicalData> getSampleClinicalData(StudyViewFilter studyViewFilter,
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<GenomicDataCountItem> getCNACountsByGeneSpecific(StudyViewFilter studyViewFilter, List<GenomicDataFilter> genomicDataFilters) {
@@ -208,7 +208,7 @@ public List<GenomicDataCountItem> getCNACountsByGeneSpecific(StudyViewFilter stu
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<GenericAssayDataCountItem> getGenericAssayDataCounts(StudyViewFilter studyViewFilter, List<GenericAssayDataFilter> genericAssayDataFilters) {
@@ -217,7 +217,7 @@ public List<GenericAssayDataCountItem> getGenericAssayDataCounts(StudyViewFilter
     
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<GenomicDataCountItem> getMutationCountsByGeneSpecific(StudyViewFilter studyViewFilter, List<GenomicDataFilter> genomicDataFilters) {
@@ -238,7 +238,7 @@ public List<GenomicDataCountItem> getMutationCountsByGeneSpecific(StudyViewFilte
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     @Override
     public List<GenomicDataCountItem> getMutationTypeCountsByGeneSpecific(StudyViewFilter studyViewFilter, List<GenomicDataFilter> genomicDataFilters) {
diff --git a/src/main/java/org/cbioportal/service/impl/ViolinPlotServiceImpl.java b/src/main/java/org/cbioportal/service/impl/ViolinPlotServiceImpl.java
index 5675b855388..53e7f620874 100644
--- a/src/main/java/org/cbioportal/service/impl/ViolinPlotServiceImpl.java
+++ b/src/main/java/org/cbioportal/service/impl/ViolinPlotServiceImpl.java
@@ -20,7 +20,7 @@ public class ViolinPlotServiceImpl implements ViolinPlotService {
 
     @Cacheable(
         cacheResolver = "staticRepositoryCacheOneResolver",
-        condition = "@cacheEnabledConfig.getEnabled()"
+        condition = "@cacheEnabledConfig.getEnabledClickhouse()"
     )
     public ClinicalViolinPlotData getClinicalViolinPlotData(
         List<ClinicalData> sampleClinicalDataForViolinPlot,