diff --git a/pkg/server/BUILD.bazel b/pkg/server/BUILD.bazel
index 8a96cbf3eb85..2236c4f5e952 100644
--- a/pkg/server/BUILD.bazel
+++ b/pkg/server/BUILD.bazel
@@ -331,6 +331,7 @@ go_library(
         "@com_github_cockroachdb_redact//:redact",
         "@com_github_getsentry_sentry_go//:sentry-go",
         "@com_github_gogo_protobuf//proto",
+        "@com_github_google_pprof//profile",
         "@com_github_gorilla_mux//:mux",
         "@com_github_grpc_ecosystem_grpc_gateway//runtime:go_default_library",
         "@com_github_grpc_ecosystem_grpc_gateway//utilities:go_default_library",
diff --git a/pkg/server/status.go b/pkg/server/status.go
index 611421cc078a..8e563f3ac28d 100644
--- a/pkg/server/status.go
+++ b/pkg/server/status.go
@@ -83,6 +83,7 @@ import (
 	"github.com/cockroachdb/cockroach/pkg/util/uint128"
 	"github.com/cockroachdb/cockroach/pkg/util/uuid"
 	"github.com/cockroachdb/errors"
+	"github.com/google/pprof/profile"
 	gwruntime "github.com/grpc-ecosystem/grpc-gateway/runtime"
 	raft "go.etcd.io/raft/v3"
 	"google.golang.org/grpc"
@@ -1464,6 +1465,102 @@ func (s *statusServer) Stacks(
 	return stacksLocal(req)
 }
 
+// fetchProfileFromAllNodes fetches the CPU profiles from all live nodes in the
+// cluster and merges the samples across all profiles.
+func (s *statusServer) fetchProfileFromAllNodes(
+	ctx context.Context, req *serverpb.ProfileRequest,
+) (*serverpb.JSONResponse, error) {
+	type profData struct {
+		data []byte
+		err  error
+	}
+	type profDataResponse struct {
+		profDataByNodeID map[roachpb.NodeID]*profData
+	}
+	response := profDataResponse{profDataByNodeID: make(map[roachpb.NodeID]*profData)}
+
+	resp, err := s.Node(ctx, &serverpb.NodeRequest{NodeId: "local"})
+	if err != nil {
+		return nil, err
+	}
+	senderServerVersion := resp.Desc.ServerVersion
+	dialFn := func(ctx context.Context, nodeID roachpb.NodeID) (interface{}, error) {
+		client, err := s.dialNode(ctx, nodeID)
+		return client, err
+	}
+	nodeFn := func(ctx context.Context, client interface{}, nodeID roachpb.NodeID) (interface{}, error) {
+		// pprof.Merge can only merge samples collected on the same binary version.
+		// So we must first check that the node is running the same binary version
+		// as the node that is going to merge the profiles.
+		statusClient := client.(serverpb.StatusClient)
+		resp, err := statusClient.Node(ctx, &serverpb.NodeRequest{NodeId: "local"})
+		if err != nil {
+			return nodeID, err
+		}
+		nodeServerVersion := resp.Desc.ServerVersion
+		if !senderServerVersion.Equal(nodeServerVersion) {
+			return nil, errors.Newf("node %d has a different server version %s to the node merging CPU profiles %s",
+				nodeID, nodeServerVersion.String(), senderServerVersion.String())
+		}
+		var pd *profData
+		err = contextutil.RunWithTimeout(ctx, "fetch cpu profile", 1*time.Minute, func(ctx context.Context) error {
+			log.Infof(ctx, "fetching a CPU profile for %d", resp.Desc.NodeID)
+			resp, err := statusClient.Profile(ctx, &serverpb.ProfileRequest{
+				NodeId:  fmt.Sprintf("%d", nodeID),
+				Type:    serverpb.ProfileRequest_CPU,
+				Seconds: req.Seconds,
+				Labels:  req.Labels,
+			})
+			if err != nil {
+				return err
+			}
+			pd = &profData{data: resp.Data}
+			return nil
+		})
+		return pd, err
+	}
+	responseFn := func(nodeID roachpb.NodeID, resp interface{}) {
+		profResp := resp.(*profData)
+		response.profDataByNodeID[nodeID] = profResp
+	}
+	errorFn := func(nodeID roachpb.NodeID, err error) {
+		response.profDataByNodeID[nodeID] = &profData{err: err}
+	}
+	if err := s.iterateNodes(ctx, "cluster-wide CPU profile", dialFn, nodeFn, responseFn, errorFn); err != nil {
+		return nil, serverError(ctx, err)
+	}
+
+	profs := make([]*profile.Profile, 0, len(response.profDataByNodeID))
+	for nodeID, pd := range response.profDataByNodeID {
+		if len(pd.data) == 0 && pd.err == nil {
+			log.Warningf(ctx, "no profile collected for node %d", nodeID)
+			continue // skipped node
+		}
+
+		if pd.err != nil {
+			log.Warningf(ctx, "failed to collect profile for node %d: %v", nodeID, pd.err)
+			continue
+		}
+
+		p, err := profile.ParseData(pd.data)
+		if err != nil {
+			return nil, err
+		}
+		p.Comments = append(p.Comments, fmt.Sprintf("n%d", nodeID))
+		profs = append(profs, p)
+	}
+	mergedProfiles, err := profile.Merge(profs)
+	if err != nil {
+		return nil, err
+	}
+
+	var buf bytes.Buffer
+	if err := mergedProfiles.Write(&buf); err != nil {
+		return nil, status.Errorf(codes.Internal, err.Error())
+	}
+	return &serverpb.JSONResponse{Data: buf.Bytes()}, nil
+}
+
 // TODO(tschottdorf): significant overlap with /debug/pprof/heap, except that
 // this one allows querying by NodeID.
 //
@@ -1481,6 +1578,12 @@ func (s *statusServer) Profile(
 		return nil, err
 	}
 
+	// If the request is for "all" nodes then we collect profiles from all nodes
+	// in the cluster and merge them before returning to the user.
+	if req.NodeId == "all" {
+		return s.fetchProfileFromAllNodes(ctx, req)
+	}
+
 	nodeID, local, err := s.parseNodeID(req.NodeId)
 	if err != nil {
 		return nil, status.Errorf(codes.InvalidArgument, err.Error())
diff --git a/pkg/ui/workspaces/db-console/src/views/reports/containers/debug/index.tsx b/pkg/ui/workspaces/db-console/src/views/reports/containers/debug/index.tsx
index 1c19eb6e869b..efd3a0c7497b 100644
--- a/pkg/ui/workspaces/db-console/src/views/reports/containers/debug/index.tsx
+++ b/pkg/ui/workspaces/db-console/src/views/reports/containers/debug/index.tsx
@@ -445,6 +445,11 @@ export default function Debug() {
             url="debug/pprof/ui/cpu/"
             params={{ node: nodeID, seconds: "5", labels: "true" }}
           />
+          <DebugTableLink
+            name="Cluster-wide CPU Profile (profiles all nodes; MEMORY OVERHEAD)"
+            url="debug/pprof/ui/cpu/"
+            params={{ node: "all", seconds: "5", labels: "true" }}
+          />
           <DebugTableLink
             name="Block"
             url="debug/pprof/ui/block/"