BA.2.9 sublineage with Orf8:A65V (466 seqs) Denmark, Belgium, Germany

[FedeGueli]

From #524 (credits for the analysis to @corneliusroemer )
i propose here a sublineage of BA.2.9 carrying Orf8:A65V mutation
It reached 466 seqs and it is circulating in multiple countries (Denmark,Germany, Belgium)
Iit has a growth advantage on parental BA.2.9 and over BA.2 baseline:
https://cov-spectrum.org/explore/World/AllSamples/Past6M/variants?pangoLineage=BA.2.9*&aaMutations1=orf8%3A65V&pangoLineage1=BA.2.9*&analysisMode=CompareToBaseline&

But probably that is cause BA.2 + S:I68T +orf8:65V is missassigned as BA.2.9 (and brings artifactually the total BA.2.9 +orf8:65V count to over 1000 seqs

When i go calculating its growth advantage considering just real BA.2.9 (with orf3a:H78Y ) this advantage dissapears:

https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?pangoLineage=BA.2*&aaMutations1=orf8%3A65V%2Corf3a%3A78Y&pangoLineage1=BA.2.9*&analysisMode=CompareToBaseline&

Very clear on Usher ( tree by @bykudh who first noticed Orf8:65V):
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/singleSubtreeAuspice_genome_3507e_9f3210.json?branchLabel=aa%20mutations&c=gt-ORF8_65&label=nuc%20mutations:C25624T

[FedeGueli]

I'll close this issie until the unreal BA.2.9 /S:I68T thing will be defined ( cfr #565 )