diff --git a/src/dxvk/dxvk_memory.cpp b/src/dxvk/dxvk_memory.cpp
index 9eabd90d913..e7393cd6688 100644
--- a/src/dxvk/dxvk_memory.cpp
+++ b/src/dxvk/dxvk_memory.cpp
@@ -322,7 +322,7 @@ namespace dxvk {
     }
 
     // Create global buffer if the allocation supports it
-    if (type.bufferUsage && !next) {
+    if (type.bufferUsage && !next && !(size & (GlobalBufferAlignment - 1u))) {
       VkBuffer buffer = VK_NULL_HANDLE;
 
       VkBufferCreateInfo bufferInfo = { VK_STRUCTURE_TYPE_BUFFER_CREATE_INFO };
diff --git a/src/dxvk/dxvk_memory.h b/src/dxvk/dxvk_memory.h
index 4e55b4ed61c..59c45a8dad6 100644
--- a/src/dxvk/dxvk_memory.h
+++ b/src/dxvk/dxvk_memory.h
@@ -335,6 +335,10 @@ namespace dxvk {
 
     constexpr static VkDeviceSize MinChunkSize =   4ull << 20;
     constexpr static VkDeviceSize MaxChunkSize = 256ull << 20;
+
+    // Assume an alignment of 256 bytes. This is enough to satisfy all
+    // buffer use cases, and matches our minimum allocation size.
+    constexpr static VkDeviceSize GlobalBufferAlignment = 256u;
   public:
     
     DxvkMemoryAllocator(DxvkDevice* device);