diff --git a/src/Features/Core/Portable/ExternalAccess/VSTypeScript/VSTypeScriptWellKnownDiagnosticCustomTags.cs b/src/Features/Core/Portable/ExternalAccess/VSTypeScript/VSTypeScriptWellKnownDiagnosticCustomTags.cs
new file mode 100644
index 0000000000000..ecb1bb0aee389
--- /dev/null
+++ b/src/Features/Core/Portable/ExternalAccess/VSTypeScript/VSTypeScriptWellKnownDiagnosticCustomTags.cs
@@ -0,0 +1,13 @@
+// Licensed to the .NET Foundation under one or more agreements.
+// The .NET Foundation licenses this file to you under the MIT license.
+// See the LICENSE file in the project root for more information.
+
+using Microsoft.CodeAnalysis.Diagnostics;
+
+namespace Microsoft.CodeAnalysis.ExternalAccess.VSTypeScript
+{
+    internal static class VSTypeScriptWellKnownDiagnosticCustomTags
+    {
+        public const string DoesNotSupportF1Help = WellKnownDiagnosticCustomTags.DoesNotSupportF1Help;
+    }
+}
diff --git a/src/VisualStudio/Core/Def/TableDataSource/VisualStudioBaseDiagnosticListTable.LiveTableDataSource.cs b/src/VisualStudio/Core/Def/TableDataSource/VisualStudioBaseDiagnosticListTable.LiveTableDataSource.cs
index 2ea56f6113f3d..59ff6434df638 100644
--- a/src/VisualStudio/Core/Def/TableDataSource/VisualStudioBaseDiagnosticListTable.LiveTableDataSource.cs
+++ b/src/VisualStudio/Core/Def/TableDataSource/VisualStudioBaseDiagnosticListTable.LiveTableDataSource.cs
@@ -367,7 +367,7 @@ public override bool TryGetValue(int index, string columnName, [NotNullWhen(retu
                             content = (data.GetValidHelpLinkUri() != null) ? string.Format(EditorFeaturesResources.Get_help_for_0, data.Id) : null;
                             return content != null;
                         case StandardTableKeyNames.HelpKeyword:
-                            content = data.Id;
+                            content = data.GetHelpKeyword();
                             return content != null;
                         case StandardTableKeyNames.HelpLink:
                             content = data.GetValidHelpLinkUri()?.AbsoluteUri;
diff --git a/src/VisualStudio/Core/Def/TableDataSource/VisualStudioDiagnosticListTable.BuildTableDataSource.cs b/src/VisualStudio/Core/Def/TableDataSource/VisualStudioDiagnosticListTable.BuildTableDataSource.cs
index 83ec3f031b8d4..436bb18e61f07 100644
--- a/src/VisualStudio/Core/Def/TableDataSource/VisualStudioDiagnosticListTable.BuildTableDataSource.cs
+++ b/src/VisualStudio/Core/Def/TableDataSource/VisualStudioDiagnosticListTable.BuildTableDataSource.cs
@@ -162,7 +162,7 @@ public override bool TryGetValue(int index, string columnName, [NotNullWhen(true
                                 content = (data.GetValidHelpLinkUri() != null) ? string.Format(EditorFeaturesResources.Get_help_for_0, data.Id) : null;
                                 return content != null;
                             case StandardTableKeyNames.HelpKeyword:
-                                content = data.Id;
+                                content = data.GetHelpKeyword();
                                 return content != null;
                             case StandardTableKeyNames.HelpLink:
                                 content = data.GetValidHelpLinkUri()?.AbsoluteUri;
diff --git a/src/VisualStudio/Core/Test/Diagnostics/DiagnosticTableDataSourceTests.vb b/src/VisualStudio/Core/Test/Diagnostics/DiagnosticTableDataSourceTests.vb
index dc547a1c56aca..344171ac4cad3 100644
--- a/src/VisualStudio/Core/Test/Diagnostics/DiagnosticTableDataSourceTests.vb
+++ b/src/VisualStudio/Core/Test/Diagnostics/DiagnosticTableDataSourceTests.vb
@@ -474,7 +474,8 @@ Namespace Microsoft.VisualStudio.LanguageServices.UnitTests.Diagnostics
                 Dim projectId = documentId.ProjectId
 
                 Dim item1 = CreateItem(workspace.CurrentSolution, projectId, documentId, DiagnosticSeverity.Error, "http://link/")
-                Dim provider = New TestDiagnosticService(item1)
+                Dim item2 = CreateItem(workspace.CurrentSolution, projectId, documentId, DiagnosticSeverity.Error, customTags:={WellKnownDiagnosticCustomTags.DoesNotSupportF1Help})
+                Dim provider = New TestDiagnosticService(item1, item2)
 
                 Dim tableManagerProvider = New TestTableManagerProvider()
 
@@ -487,12 +488,13 @@ Namespace Microsoft.VisualStudio.LanguageServices.UnitTests.Diagnostics
 
                 Dim sink = DirectCast(sinkAndSubscription.Key, TestTableManagerProvider.TestTableManager.TestSink)
                 Dim snapshot = sink.Entries.First().GetCurrentSnapshot()
-                Assert.Equal(1, snapshot.Count)
+                Assert.Equal(2, snapshot.Count)
 
                 Dim keyword As Object = Nothing
                 Assert.True(snapshot.TryGetValue(0, StandardTableKeyNames.HelpKeyword, keyword))
-
                 Assert.Equal(item1.Id, keyword.ToString())
+
+                Assert.False(snapshot.TryGetValue(1, StandardTableKeyNames.HelpKeyword, keyword))
             End Using
         End Sub
 
@@ -762,7 +764,7 @@ Namespace Microsoft.VisualStudio.LanguageServices.UnitTests.Diagnostics
             Return CreateItem(solution, documentId.ProjectId, documentId, severity)
         End Function
 
-        Private Shared Function CreateItem(solution As Solution, projectId As ProjectId, documentId As DocumentId, Optional severity As DiagnosticSeverity = DiagnosticSeverity.Error, Optional link As String = Nothing) As DiagnosticData
+        Private Shared Function CreateItem(solution As Solution, projectId As ProjectId, documentId As DocumentId, Optional severity As DiagnosticSeverity = DiagnosticSeverity.Error, Optional link As String = Nothing, Optional customTags As String() = Nothing) As DiagnosticData
             Dim location =
                 If(documentId Is Nothing,
                     If(projectId Is Nothing, New DiagnosticDataLocation(New FileLinePositionSpan("", Nothing)), New DiagnosticDataLocation(New FileLinePositionSpan(solution.GetProject(projectId).FilePath, Nothing))),
@@ -776,7 +778,7 @@ Namespace Microsoft.VisualStudio.LanguageServices.UnitTests.Diagnostics
                 defaultSeverity:=severity,
                 isEnabledByDefault:=True,
                 warningLevel:=0,
-                customTags:=ImmutableArray(Of String).Empty,
+                customTags:=If(customTags IsNot Nothing, customTags.ToImmutableArray(), ImmutableArray(Of String).Empty),
                 properties:=ImmutableDictionary(Of String, String).Empty,
                 projectId,
                 location:=location,
diff --git a/src/Workspaces/Core/Portable/Diagnostics/DiagnosticData.cs b/src/Workspaces/Core/Portable/Diagnostics/DiagnosticData.cs
index fd90ec0336daf..2ee99aca89b96 100644
--- a/src/Workspaces/Core/Portable/Diagnostics/DiagnosticData.cs
+++ b/src/Workspaces/Core/Portable/Diagnostics/DiagnosticData.cs
@@ -368,5 +368,9 @@ internal bool IsBuildDiagnostic()
         // TODO: the value stored in HelpLink should already be valid URI (https://github.com/dotnet/roslyn/issues/59205)
         internal Uri? GetValidHelpLinkUri()
             => Uri.TryCreate(HelpLink, UriKind.Absolute, out var uri) ? uri : null;
+
+        // Return the diagnostic ID as the HelpKeyword, unless the diagnostic does support F1 help for keyword.
+        internal string? GetHelpKeyword()
+            => CustomTags.Contains(WellKnownDiagnosticCustomTags.DoesNotSupportF1Help) ? null : Id;
     }
 }
diff --git a/src/Workspaces/Core/Portable/Diagnostics/WellKnownDiagnosticCustomTags.cs b/src/Workspaces/Core/Portable/Diagnostics/WellKnownDiagnosticCustomTags.cs
new file mode 100644
index 0000000000000..fe2f16264d5e4
--- /dev/null
+++ b/src/Workspaces/Core/Portable/Diagnostics/WellKnownDiagnosticCustomTags.cs
@@ -0,0 +1,11 @@
+// Licensed to the .NET Foundation under one or more agreements.
+// The .NET Foundation licenses this file to you under the MIT license.
+// See the LICENSE file in the project root for more information.
+
+namespace Microsoft.CodeAnalysis.Diagnostics
+{
+    internal static class WellKnownDiagnosticCustomTags
+    {
+        public const string DoesNotSupportF1Help = nameof(DoesNotSupportF1Help);
+    }
+}