diff --git a/eng/pipelines/common/evaluate-default-paths.yml b/eng/pipelines/common/evaluate-default-paths.yml
index fd0697b027c5b..d77e8a9de715f 100644
--- a/eng/pipelines/common/evaluate-default-paths.yml
+++ b/eng/pipelines/common/evaluate-default-paths.yml
@@ -7,9 +7,14 @@ parameters:
   _const_paths:
     _wasm_specific_only: [
         eng/testing/ProvisioningVersions.props
+        eng/testing/WasmRunner*
+        eng/testing/WasiRunner*
         eng/testing/scenarios/BuildWasmAppsJobsList.txt
-        eng/testing/tests.wasm.targets
+        eng/testing/tests.browser.targets
+        eng/testing/tests.was*.targets
+        eng/testing/was*provisioning.targets
         src/libraries/sendtohelix-wasm.targets
+        src/libraries/sendtohelix-wasi.targets
         src/mono/mono/**/*wasm*
         src/mono/nuget/Microsoft.NET.Runtime.WebAssembly.Sdk/*
         src/mono/nuget/Microsoft.NET.Runtime.wasm.Sample.Mono/*
@@ -70,6 +75,7 @@ jobs:
       - eng/pipelines/installer/*
       - eng/pipelines/mono/*
       - eng/pipelines/libraries/*
+      - ${{ parameters._const_paths._wasm_specific_only }}
       - ${{ parameters._const_paths._wasm_pipelines }}
       - ${{ parameters._const_paths._always_exclude }}
 
diff --git a/eng/pipelines/common/templates/wasm-debugger-tests.yml b/eng/pipelines/common/templates/wasm-debugger-tests.yml
index 994b169df9a00..4d8ec6e67d4b7 100644
--- a/eng/pipelines/common/templates/wasm-debugger-tests.yml
+++ b/eng/pipelines/common/templates/wasm-debugger-tests.yml
@@ -4,6 +4,7 @@ parameters:
   isWasmOnlyBuild: false
   browser: 'chrome'
   shouldContinueOnError: false
+  runOnlyOnWasmOnlyPipelines: false
   extraBuildArgs: ''
   nameSuffix: ''
   platforms: []
@@ -23,6 +24,8 @@ jobs:
       # map dependencies variables to local variables
       - name: alwaysRunVar
         value: ${{ parameters.alwaysRun }}
+      - name: runOnlyOnWasmPipelinesVar
+        value: ${{ parameters.runOnlyOnWasmOnlyPipelines }}
       - name: shouldRunOnDefaultPipelines
         value: $[
           or(
@@ -47,7 +50,9 @@ jobs:
       condition: >-
         or(
           eq(variables['alwaysRunVar'], true),
-          eq(variables['isDefaultPipeline'], variables['shouldRunOnDefaultPipelines']))
+          and(
+            eq(variables['isDefaultPipeline'], variables['shouldRunOnDefaultPipelines']),
+            ne(variables['runOnlyOnWasmPipelinesVar'], 'true')))
       extraStepsTemplate: /eng/pipelines/libraries/helix.yml
       extraStepsParameters:
         creator: dotnet-bot
diff --git a/eng/pipelines/extra-platforms/runtime-extra-platforms-wasm.yml b/eng/pipelines/extra-platforms/runtime-extra-platforms-wasm.yml
index d1b25fde40514..de1be931bf469 100644
--- a/eng/pipelines/extra-platforms/runtime-extra-platforms-wasm.yml
+++ b/eng/pipelines/extra-platforms/runtime-extra-platforms-wasm.yml
@@ -241,6 +241,7 @@ jobs:
       alwaysRun: ${{ parameters.isWasmOnlyBuild }}
       isExtraPlatformsBuild: ${{ parameters.isExtraPlatformsBuild }}
       isWasmOnlyBuild: ${{ parameters.isWasmOnlyBuild }}
+      runOnlyOnWasmOnlyPipelines: true
 
   # Disable for now
   #- template: /eng/pipelines/coreclr/perf-wasm-jobs.yml
diff --git a/eng/pipelines/runtime-wasm-optional.yml b/eng/pipelines/runtime-wasm-optional.yml
index 86840d3e35db9..a1392e6245617 100644
--- a/eng/pipelines/runtime-wasm-optional.yml
+++ b/eng/pipelines/runtime-wasm-optional.yml
@@ -1,8 +1,5 @@
-# This is a wrapper yml for `extra-platforms/runtime-extra-platforms-wasm.yml`, which
-# has all the wasm jobs. This file is essentially so we can have point
-# the pipeline in azdo UI to this, and thus avoid any scheduled triggers
-
 trigger: none
+pr: none
 
 variables:
   - template: /eng/pipelines/common/variables.yml