diff --git a/easybuild/easyconfigs/v/vcflib/vcflib-1.0.9-foss-2022a-R-4.2.1.eb b/easybuild/easyconfigs/v/vcflib/vcflib-1.0.9-foss-2022a-R-4.2.1.eb
index 32a39ef352a0..0ae4911c54b5 100644
--- a/easybuild/easyconfigs/v/vcflib/vcflib-1.0.9-foss-2022a-R-4.2.1.eb
+++ b/easybuild/easyconfigs/v/vcflib/vcflib-1.0.9-foss-2022a-R-4.2.1.eb
@@ -57,7 +57,8 @@ preconfigopts += " -e 's|multichoose.h|multichoose/multichoose.h|g' -e 's|fileve
 preconfigopts += " -e 's|tabix.hpp|tabixpp/tabix.hpp|g' -e 's|Fasta.h|fastahack/Fasta.h|g'"
 preconfigopts += r" -e 's|disorder.h|smithwaterman/disorder.h|g' {} \; && "
 
-configopts = "-DZIG=OFF -DWFA_GITMODULE=OFF -DWFA_INCLUDE_DIRS=$EBROOTWFA2/include/wfa2lib"
+configopts = "-DZIG=OFF -DWFA_GITMODULE=OFF -DWFA_INCLUDE_DIRS=$EBROOTWFA2/include/wfa2lib "
+configopts += "-DPYTHON_EXECUTABLE=$EBROOTPYTHON/bin/python"
 
 postinstallcmds = ["cp -r %(builddir)s/%(name)s-%(version)s/scripts %(installdir)s"]