diff --git a/tests/core/middleware/test_simple_cache_middleware.py b/tests/core/middleware/test_simple_cache_middleware.py
index 11ba2b8026..a68dbc79e2 100644
--- a/tests/core/middleware/test_simple_cache_middleware.py
+++ b/tests/core/middleware/test_simple_cache_middleware.py
@@ -5,6 +5,7 @@
 
 from web3 import Web3
 from web3._utils.caching import (
+    SimpleCache,
     generate_cache_key,
 )
 from web3.middleware import (
@@ -51,13 +52,33 @@ def w3(w3_base, result_generator_middleware):
     return w3_base
 
 
-def test_simple_cache_middleware_pulls_from_cache(w3):
-    def cache_class():
-        return {
-            generate_cache_key(f"{threading.get_ident()}:{('fake_endpoint', [1])}"): {
-                "result": "value-a"
-            },
-        }
+def dict_cache_class_return_value_a():
+    # test dictionary-based cache
+    return {
+        generate_cache_key(f"{threading.get_ident()}:{('fake_endpoint', [1])}"): {
+            "result": "value-a"
+        },
+    }
+
+
+def simple_cache_class_return_value_a():
+    # test `SimpleCache` class cache
+    _cache = SimpleCache()
+    _cache.cache(
+        generate_cache_key(f"{threading.get_ident()}:{('fake_endpoint', [1])}"),
+        {"result": "value-a"},
+    )
+    return _cache
+
+
+@pytest.mark.parametrize(
+    "cache_class",
+    (
+        dict_cache_class_return_value_a,
+        simple_cache_class_return_value_a,
+    ),
+)
+def test_simple_cache_middleware_pulls_from_cache(w3, cache_class):
 
     w3.middleware_onion.add(
         construct_simple_cache_middleware(
@@ -69,10 +90,11 @@ def cache_class():
     assert w3.manager.request_blocking("fake_endpoint", [1]) == "value-a"
 
 
-def test_simple_cache_middleware_populates_cache(w3):
+@pytest.mark.parametrize("cache_class", (dict, SimpleCache))
+def test_simple_cache_middleware_populates_cache(w3, cache_class):
     w3.middleware_onion.add(
         construct_simple_cache_middleware(
-            cache_class=dict,
+            cache_class=cache_class,
             rpc_whitelist={RPCEndpoint("fake_endpoint")},
         )
     )
@@ -83,7 +105,8 @@ def test_simple_cache_middleware_populates_cache(w3):
     assert w3.manager.request_blocking("fake_endpoint", [1]) != result
 
 
-def test_simple_cache_middleware_does_not_cache_none_responses(w3_base):
+@pytest.mark.parametrize("cache_class", (dict, SimpleCache))
+def test_simple_cache_middleware_does_not_cache_none_responses(w3_base, cache_class):
     counter = itertools.count()
     w3 = w3_base
 
@@ -101,7 +124,7 @@ def result_cb(_method, _params):
 
     w3.middleware_onion.add(
         construct_simple_cache_middleware(
-            cache_class=dict,
+            cache_class=cache_class,
             rpc_whitelist={RPCEndpoint("fake_endpoint")},
         )
     )
@@ -112,7 +135,8 @@ def result_cb(_method, _params):
     assert next(counter) == 2
 
 
-def test_simple_cache_middleware_does_not_cache_error_responses(w3_base):
+@pytest.mark.parametrize("cache_class", (dict, SimpleCache))
+def test_simple_cache_middleware_does_not_cache_error_responses(w3_base, cache_class):
     w3 = w3_base
     w3.middleware_onion.add(
         construct_error_generator_middleware(
@@ -124,7 +148,7 @@ def test_simple_cache_middleware_does_not_cache_error_responses(w3_base):
 
     w3.middleware_onion.add(
         construct_simple_cache_middleware(
-            cache_class=dict,
+            cache_class=cache_class,
             rpc_whitelist={RPCEndpoint("fake_endpoint")},
         )
     )
@@ -137,10 +161,14 @@ def test_simple_cache_middleware_does_not_cache_error_responses(w3_base):
     assert str(err_a) != str(err_b)
 
 
-def test_simple_cache_middleware_does_not_cache_endpoints_not_in_whitelist(w3):
+@pytest.mark.parametrize("cache_class", (dict, SimpleCache))
+def test_simple_cache_middleware_does_not_cache_endpoints_not_in_whitelist(
+    w3,
+    cache_class,
+):
     w3.middleware_onion.add(
         construct_simple_cache_middleware(
-            cache_class=dict,
+            cache_class=cache_class,
             rpc_whitelist={RPCEndpoint("fake_endpoint")},
         )
     )
@@ -156,7 +184,7 @@ def test_simple_cache_middleware_does_not_cache_endpoints_not_in_whitelist(w3):
 
 async def _async_simple_cache_middleware_for_testing(make_request, async_w3):
     middleware = await async_construct_simple_cache_middleware(
-        cache_class=dict,
+        cache_class=SimpleCache,
         rpc_whitelist={RPCEndpoint("fake_endpoint")},
     )
     return await middleware(make_request, async_w3)
@@ -173,17 +201,17 @@ def async_w3():
 
 
 @pytest.mark.asyncio
-async def test_async_simple_cache_middleware_pulls_from_cache(async_w3):
+@pytest.mark.parametrize(
+    "cache_class",
+    (
+        dict_cache_class_return_value_a,
+        simple_cache_class_return_value_a,
+    ),
+)
+async def test_async_simple_cache_middleware_pulls_from_cache(async_w3, cache_class):
     # remove the pre-loaded simple cache middleware to replace with test-specific:
     async_w3.middleware_onion.remove("simple_cache")
 
-    def cache_class():
-        return {
-            generate_cache_key(f"{threading.get_ident()}:{('fake_endpoint', [1])}"): {
-                "result": "value-a"
-            },
-        }
-
     async def _properly_awaited_middleware(make_request, _async_w3):
         middleware = await async_construct_simple_cache_middleware(
             cache_class=cache_class,