diff --git a/.changeset/puny-bats-smell.md b/.changeset/puny-bats-smell.md
new file mode 100644
index 000000000000..9674004f0873
--- /dev/null
+++ b/.changeset/puny-bats-smell.md
@@ -0,0 +1,5 @@
+---
+"gradio": patch
+---
+
+feat:Raise WasmUnsupportedError for ffmpeg usage on Lite
diff --git a/gradio/components/audio.py b/gradio/components/audio.py
index 34f7f3986cac..45f8b0e25d16 100644
--- a/gradio/components/audio.py
+++ b/gradio/components/audio.py
@@ -16,7 +16,7 @@
 from gradio_client.documentation import document
 from pydub import AudioSegment
 
-from gradio import processing_utils, utils
+from gradio import processing_utils, utils, wasm_utils
 from gradio.components.base import Component, StreamingInput, StreamingOutput
 from gradio.data_classes import FileData, FileDataDict, MediaStreamChunk
 from gradio.events import Events
@@ -311,6 +311,10 @@ def postprocess(
 
     @staticmethod
     def _convert_to_adts(data: bytes):
+        if wasm_utils.IS_WASM:
+            raise wasm_utils.WasmUnsupportedError(
+                "Audio streaming is not supported in the Wasm mode."
+            )
         segment = AudioSegment.from_file(io.BytesIO(data))
 
         buffer = io.BytesIO()
diff --git a/gradio/components/video.py b/gradio/components/video.py
index 8464f3a57289..34c0006f242b 100644
--- a/gradio/components/video.py
+++ b/gradio/components/video.py
@@ -424,6 +424,11 @@ def example_value(self) -> Any:
 
     @staticmethod
     def get_video_duration_ffprobe(filename: str):
+        if wasm_utils.IS_WASM:
+            raise wasm_utils.WasmUnsupportedError(
+                "ffprobe is not supported in the Wasm mode."
+            )
+
         result = subprocess.run(
             [
                 "ffprobe",
@@ -454,6 +459,11 @@ def get_video_duration_ffprobe(filename: str):
 
     @staticmethod
     async def async_convert_mp4_to_ts(mp4_file, ts_file):
+        if wasm_utils.IS_WASM:
+            raise wasm_utils.WasmUnsupportedError(
+                "Streaming is not supported in the Wasm mode."
+            )
+
         ff = FFmpeg(  # type: ignore
             inputs={mp4_file: None},
             outputs={
diff --git a/gradio/processing_utils.py b/gradio/processing_utils.py
index b003ec57d83f..c04ec7685716 100644
--- a/gradio/processing_utils.py
+++ b/gradio/processing_utils.py
@@ -628,6 +628,12 @@ def audio_from_file(
             else ""
         )
         raise RuntimeError(msg) from e
+    except OSError as e:
+        if wasm_utils.IS_WASM:
+            raise wasm_utils.WasmUnsupportedError(
+                "Audio format conversion is not supported in the Wasm mode."
+            ) from e
+        raise e
     if crop_min != 0 or crop_max != 100:
         audio_start = len(audio) * crop_min / 100
         audio_end = len(audio) * crop_max / 100
@@ -641,6 +647,10 @@ def audio_from_file(
 def audio_to_file(sample_rate, data, filename, format="wav"):
     if format == "wav":
         data = convert_to_16_bit_wav(data)
+    elif wasm_utils.IS_WASM:
+        raise wasm_utils.WasmUnsupportedError(
+            "Audio formats other than .wav are not supported in the Wasm mode."
+        )
     audio = AudioSegment(
         data.tobytes(),
         frame_rate=sample_rate,