diff --git a/.github/workflows/pythonapp.yml b/.github/workflows/pythonapp.yml
index e92e2b201c..781c956b8e 100644
--- a/.github/workflows/pythonapp.yml
+++ b/.github/workflows/pythonapp.yml
@@ -237,3 +237,38 @@ jobs:
           pytest -v
           test/test_cvedb.py
           test/test_cli.py
+
+  cve_scan:
+    name: CVE Scan on dependencies
+    runs-on: ubuntu-latest
+    timeout-minutes: 10
+    steps:
+      - name: Get Date
+        id: get-date
+        run: |
+          echo "::set-output name=date::$(/bin/date -u "+%Y%m%d")"
+        shell: bash
+      - uses: actions/checkout@v2
+      - name: Set up Python
+        uses: actions/setup-python@v1
+        with:
+          python-version: 3.8
+      - name: get cached python packages
+        uses: actions/cache@v2
+        with:
+          path: ~/.cache/pip
+          key: ${{ runner.os }}-pip-${{ hashFiles('**/requirements.txt') }}
+          restore-keys: |
+            ${{ runner.os }}-pip-
+      - name: get cached database
+        uses: actions/cache@v2
+        with:
+          path: ~/.cache/cve-bin-tool
+          key: ${{ runner.os }}-cve-bin-tool-${{ steps.get-date.outputs.date }}
+      - name: Install dependencies
+        run: |
+          python -m pip install --upgrade pip
+          pip install -r requirements.txt -r doc/requirements.txt
+      - name: Test to check for CVEs for python requirements and HTML report dependencies
+        run: |
+          pytest test/test_requirements.py
diff --git a/.gitignore b/.gitignore
index d08df3b0e2..13d12ad514 100644
--- a/.gitignore
+++ b/.gitignore
@@ -15,4 +15,5 @@ build/
 dist/
 doc/_build
 test/downloads/
+cve_bin_tool_requirements.csv
 !test/condensed-downloads/*.tar.gz
diff --git a/cve_bin_tool/output_engine/html_reports/js/dependencies.csv b/cve_bin_tool/output_engine/html_reports/js/dependencies.csv
new file mode 100644
index 0000000000..77c4925a92
--- /dev/null
+++ b/cve_bin_tool/output_engine/html_reports/js/dependencies.csv
@@ -0,0 +1,4 @@
+vendor,product
+getbootstrap,bootstrap
+jquery,jquery
+plotly,plotly.js
diff --git a/doc/requirements.csv b/doc/requirements.csv
new file mode 100644
index 0000000000..0497e9fbe2
--- /dev/null
+++ b/doc/requirements.csv
@@ -0,0 +1,4 @@
+vendor,product
+rtfd_not_in_db,recommonmark
+sphinx-doc_not_in_db,Sphinx
+ryanfox_not_in_db,sphinx_markdown_tables
diff --git a/requirements.csv b/requirements.csv
new file mode 100644
index 0000000000..70288ab7d2
--- /dev/null
+++ b/requirements.csv
@@ -0,0 +1,18 @@
+vendor,product
+plot,plotly
+pocoo,jinja2
+aiohttp_project,aiohttp
+pyyaml,pyyaml
+reportlab,reportlab
+pytest_not_in_db,pytest
+pytest_not_in_db,pytest-xdist
+pytest_not_in_db,pytest-cov
+pytest_not_in_db,pytest-asyncio
+pycqa_not_in_db,isort
+willmcgugan_not_in_db,rich
+crummy_not_in_db,beautifulsoup4
+uiri_not_in_db,toml
+jsonschema_not_in_db,jsonschema
+python_not_in_db,py
+srossross_not_in_db,rpmfile
+indygreg_not_in_db,zstandard
diff --git a/test/test_requirements.py b/test/test_requirements.py
new file mode 100644
index 0000000000..f6f05f0989
--- /dev/null
+++ b/test/test_requirements.py
@@ -0,0 +1,138 @@
+# Copyright (C) 2021 Intel Corporation
+# SPDX-License-Identifier: GPL-3.0-or-later
+
+import csv
+import re
+import subprocess
+from importlib.metadata import version
+from os.path import dirname, join
+
+ROOT_PATH = join(dirname(__file__), "..")
+
+REQ_TXT = join(ROOT_PATH, "requirements.txt")
+REQ_CSV = join(ROOT_PATH, "requirements.csv")
+DOC_TXT = join(ROOT_PATH, "doc", "requirements.txt")
+DOC_CSV = join(ROOT_PATH, "doc", "requirements.csv")
+
+SCAN_CSV = join(ROOT_PATH, "cve_bin_tool_requirements.csv")
+
+HTML_DEP_PATH = join(
+    ROOT_PATH,
+    "cve_bin_tool",
+    "output_engine",
+    "html_reports",
+    "js",
+)
+
+HTML_DEP_CSV = join(HTML_DEP_PATH, "dependencies.csv")
+
+# Dependencies that currently have CVEs
+# Remove from the list once they are updated
+ALLOWED_PACKAGES = ["reportlab"]
+
+
+def get_out_of_sync_packages(csv_name, txt_name):
+
+    new_packages = set()
+    removed_packages = set()
+    csv_package_names = set()
+    txt_package_names = set()
+
+    with open(csv_name) as csv_file, open(txt_name) as txt_file:
+        csv_reader = csv.reader(csv_file)
+        next(csv_reader)
+        for (_, product) in csv_reader:
+            csv_package_names.add(product)
+        lines = txt_file.readlines()
+        for line in lines:
+            txt_package_names.add(re.split(">|\\[|;|=|\n", line)[0])
+        new_packages = txt_package_names - csv_package_names
+        removed_packages = csv_package_names - txt_package_names
+
+    return (new_packages, removed_packages)
+
+
+# Test to check if the requirements.csv files are in sync with requirements.txt files
+def test_txt_csv_sync():
+
+    errors = set()
+
+    (
+        req_new_packages,
+        req_removed_packages,
+    ) = get_out_of_sync_packages(REQ_CSV, REQ_TXT)
+    (
+        doc_new_packages,
+        doc_removed_packages,
+    ) = get_out_of_sync_packages(DOC_CSV, DOC_TXT)
+
+    if doc_removed_packages != set():
+        errors.add(
+            f"The requirements.txt and requirements.csv files of docs are out of sync! Please remove {', '.join(doc_removed_packages)} from the respective requirements.csv file\n"
+        )
+    if doc_new_packages != set():
+        errors.add(
+            f"The requirements.txt and requirements.csv files of docs are out of sync! Please add {', '.join(doc_new_packages)} to the respective requirements.csv file\n"
+        )
+    if req_removed_packages != set():
+        errors.add(
+            f"The requirements.txt and requirements.csv files of cve-bin-tool are out of sync! Please remove {', '.join(req_removed_packages)} from the respective requirements.csv file\n"
+        )
+    if req_new_packages != set():
+        errors.add(
+            f"The requirements.txt and requirements.csv files of cve-bin-tool are out of sync! Please add {', '.join(req_new_packages)} to the respective requirements.csv file\n"
+        )
+
+    assert errors == set(), f"The error(s) are:\n {''.join(errors)}"
+
+
+def get_cache_csv_data(file):
+
+    data = []
+
+    with open(file) as f:
+        r = csv.reader(f)
+        next(r)
+        for (vendor, product) in r:
+            if file is HTML_DEP_CSV:
+                file_name = f"{HTML_DEP_PATH}/{product}"
+                if not file_name.endswith(".js"):
+                    file_name += ".js"
+                with open(file_name) as f:
+                    file_content = f.read()
+                    html_dep_version = re.search(
+                        r"v([0-9]+\.[0-9]+\.[0-9]+)", file_content
+                    ).group(1)
+                    if product not in ALLOWED_PACKAGES:
+                        data.append((vendor, product, html_dep_version))
+            else:
+                if "_not_in_db" not in vendor and product not in ALLOWED_PACKAGES:
+                    data.append((vendor, product, version(product)))
+
+        return data
+
+
+# Test to check for CVEs in cve-bin-tool requirements/dependencies
+def test_requirements():
+
+    cache_csv_data = (
+        get_cache_csv_data(REQ_CSV)
+        + get_cache_csv_data(DOC_CSV)
+        + get_cache_csv_data(HTML_DEP_CSV)
+    )
+
+    # writes a cache CSV file
+    with open(SCAN_CSV, "w") as f:
+        writer = csv.writer(f)
+        fieldnames = ["vendor", "product", "version"]
+        writer = csv.writer(f)
+        writer.writerow(fieldnames)
+        for row in cache_csv_data:
+            writer.writerow(row)
+
+    cve_check = subprocess.run(
+        ["python", "-m", "cve_bin_tool.cli", "--input-file", SCAN_CSV]
+    )
+    assert (
+        cve_check.returncode == 0
+    ), f"{cve_check.returncode} dependencies/requirements have CVEs"