diff --git a/README.rst b/README.rst
index b827ae36e..bb81ab034 100644
--- a/README.rst
+++ b/README.rst
@@ -171,14 +171,16 @@ generated at the top of requirements files by setting the
     markupsafe==0.23          # via jinja2
     werkzeug==0.10.4          # via flask
 
-Example usage for `pip-sync`
-============================
+Example usage for ``pip-sync``
+==============================
 
 Now that you have a ``requirements.txt``, you can use ``pip-sync`` to update
 your virtual env to reflect exactly what's in there.  Note: this will
 install/upgrade/uninstall everything necessary to match the ``requirements.txt``
 contents.
 
+*Be careful: pip-sync is meant to be used only with a pip-compile'd requirements.txt.*
+
 .. code-block:: bash
 
     $ pip-sync