DESCRIPTION

Package: diem
Title: Debris-Containing Droplet Identification using EM
Version: 2.4.1
Date: 2022-12-19
Authors@R: c(person(given = "Marcus",
            family = "Alvarez", 
            role = c("aut", "cre"),
            email = "malvarez@mednet.ucla.edu"), 
        person(given = "Elior", 
            family = "Rahmani", 
            role = "aut", 
            email = "elior.rahmani@gmail.com"))
Description: Identification of debris-containing droplets 
        from a droplet-based single cell/nucleus RNA-seq. 'diem' 
        classifies droplets by modeling droplet expression with a 
        multinomial mixture model. Droplets are assigned to 
        debris or cell type clusters after estimating parameters  
        with expectation maximization (EM). Provides 
        quantifications of contamination in individual 
        droplets for filtering and use as a covariate. 
        See Alvarez M, Rahmani E, et al (2019) 
        <doi:10.1101/786285> for details.
License: GPL-3
Encoding: UTF-8
LazyData: true
RoxygenNote: 6.1.1
Depends:
	R (>= 3.5.0), 
    methods 
LinkingTo: Rcpp, RcppEigen, RcppProgress
Imports:
    ggplot2,
    Matrix,
    irlba,
    scales,
    gridExtra, 
    utils,
    stats,
    Rcpp
Suggests:
    Seurat (>= 3.0.0),
    testthat,
    knitr,
    rmarkdown
VignetteBuilder: knitr
URL: https://www.biorxiv.org/content/10.1101/786285v2
BugReports: https://github.com/marcalva/diem/issues