diff --git a/docs/pages/api-docs/card-media.json b/docs/pages/api-docs/card-media.json
index 6d6a6a01c294fc..528452a3976a72 100644
--- a/docs/pages/api-docs/card-media.json
+++ b/docs/pages/api-docs/card-media.json
@@ -4,7 +4,8 @@
     "classes": { "type": { "name": "object" } },
     "component": { "type": { "name": "elementType" } },
     "image": { "type": { "name": "string" } },
-    "src": { "type": { "name": "string" } }
+    "src": { "type": { "name": "string" } },
+    "sx": { "type": { "name": "object" } }
   },
   "name": "CardMedia",
   "styles": { "classes": ["root", "media", "img"], "globalClasses": {}, "name": "MuiCardMedia" },
@@ -13,6 +14,6 @@
   "filename": "/packages/material-ui/src/CardMedia/CardMedia.js",
   "inheritance": null,
   "demos": "<ul><li><a href=\"/components/cards/\">Cards</a></li></ul>",
-  "styledComponent": false,
+  "styledComponent": true,
   "cssComponent": false
 }
diff --git a/docs/translations/api-docs/card-media/card-media.json b/docs/translations/api-docs/card-media/card-media.json
index 549ce3ec7b894f..92515bce5e0bfc 100644
--- a/docs/translations/api-docs/card-media/card-media.json
+++ b/docs/translations/api-docs/card-media/card-media.json
@@ -5,7 +5,8 @@
     "classes": "Override or extend the styles applied to the component. See <a href=\"#css\">CSS API</a> below for more details.",
     "component": "The component used for the root node. Either a string to use a HTML element or a component.",
     "image": "Image to be displayed as a background image. Either <code>image</code> or <code>src</code> prop must be specified. Note that caller must specify height otherwise the image will not be visible.",
-    "src": "An alias for <code>image</code> property. Available only with media components. Media components: <code>video</code>, <code>audio</code>, <code>picture</code>, <code>iframe</code>, <code>img</code>."
+    "src": "An alias for <code>image</code> property. Available only with media components. Media components: <code>video</code>, <code>audio</code>, <code>picture</code>, <code>iframe</code>, <code>img</code>.",
+    "sx": "The system prop that allows defining system overrides as well as additional CSS styles. See the <a href=\"/system/basics/#the-sx-prop\">`sx` page</a> for more details."
   },
   "classDescriptions": {
     "root": { "description": "Styles applied to the root element." },
diff --git a/packages/material-ui/src/CardMedia/CardMedia.d.ts b/packages/material-ui/src/CardMedia/CardMedia.d.ts
index 7d5a6299c820fb..3ec63fbf834e55 100644
--- a/packages/material-ui/src/CardMedia/CardMedia.d.ts
+++ b/packages/material-ui/src/CardMedia/CardMedia.d.ts
@@ -1,4 +1,6 @@
+import { SxProps } from '@material-ui/system';
 import * as React from 'react';
+import { Theme } from '..';
 import { OverridableComponent, OverrideProps } from '../OverridableComponent';
 
 export interface CardMediaTypeMap<P, D extends React.ElementType> {
@@ -30,6 +32,10 @@ export interface CardMediaTypeMap<P, D extends React.ElementType> {
      * Media components: `video`, `audio`, `picture`, `iframe`, `img`.
      */
     src?: string;
+    /**
+     * The system prop that allows defining system overrides as well as additional CSS styles.
+     */
+    sx?: SxProps<Theme>;
   };
   defaultComponent: D;
 }
diff --git a/packages/material-ui/src/CardMedia/CardMedia.js b/packages/material-ui/src/CardMedia/CardMedia.js
index d28619ff1980e4..8e6e2fbd35bceb 100644
--- a/packages/material-ui/src/CardMedia/CardMedia.js
+++ b/packages/material-ui/src/CardMedia/CardMedia.js
@@ -1,63 +1,89 @@
 import * as React from 'react';
 import PropTypes from 'prop-types';
 import clsx from 'clsx';
-import { chainPropTypes } from '@material-ui/utils';
-import withStyles from '../styles/withStyles';
+import { chainPropTypes, deepmerge } from '@material-ui/utils';
+import { unstable_composeClasses as composeClasses } from '@material-ui/unstyled';
+import useThemeProps from '../styles/useThemeProps';
+import experimentalStyled from '../styles/experimentalStyled';
+import { getCardMediaUtilityClass } from './cardMediaClasses';
 
-export const styles = {
-  /* Styles applied to the root element. */
-  root: {
-    display: 'block',
-    backgroundSize: 'cover',
-    backgroundRepeat: 'no-repeat',
-    backgroundPosition: 'center',
+const overridesResolver = (props, styles) => {
+  const { styleProps } = props;
+  const { isMediaComponent, isImageComponent } = styleProps;
+
+  return deepmerge(styles.root || {}, {
+    ...(isMediaComponent && styles.media),
+    ...(isImageComponent && styles.img),
+  });
+};
+
+const useUtilityClasses = (styleProps) => {
+  const { classes, isMediaComponent, isImageComponent } = styleProps;
+
+  const slots = {
+    root: ['root', isMediaComponent && 'media', isImageComponent && 'img'],
+  };
+
+  return composeClasses(slots, getCardMediaUtilityClass, classes);
+};
+
+const CardMediaRoot = experimentalStyled(
+  'div',
+  {},
+  {
+    name: 'MuiCardMedia',
+    slot: 'Root',
+    overridesResolver,
   },
+)(({ styleProps }) => ({
+  /* Styles applied to the root element. */
+  display: 'block',
+  backgroundSize: 'cover',
+  backgroundRepeat: 'no-repeat',
+  backgroundPosition: 'center',
   /* Styles applied to the root element if `component="video, audio, picture, iframe, or img"`. */
-  media: {
+  ...(styleProps.isMediaComponent && {
     width: '100%',
-  },
+  }),
   /* Styles applied to the root element if `component="picture or img"`. */
-  img: {
+  ...(styleProps.isImageComponent && {
     // ⚠️ object-fit is not supported by IE11.
     objectFit: 'cover',
-  },
-};
+  }),
+}));
 
 const MEDIA_COMPONENTS = ['video', 'audio', 'picture', 'iframe', 'img'];
+const IMAGE_COMPONENTS = ['picture', 'img'];
 
-const CardMedia = React.forwardRef(function CardMedia(props, ref) {
-  const {
-    children,
-    classes,
-    className,
-    component: Component = 'div',
-    image,
-    src,
-    style,
-    ...other
-  } = props;
+const CardMedia = React.forwardRef(function CardMedia(inProps, ref) {
+  const props = useThemeProps({ props: inProps, name: 'MuiCardMedia' });
+  const { children, className, component = 'div', image, src, style, ...other } = props;
 
-  const isMediaComponent = MEDIA_COMPONENTS.indexOf(Component) !== -1;
+  const isMediaComponent = MEDIA_COMPONENTS.indexOf(component) !== -1;
   const composedStyle =
     !isMediaComponent && image ? { backgroundImage: `url("${image}")`, ...style } : style;
 
+  const styleProps = {
+    ...props,
+    component,
+    isMediaComponent,
+    isImageComponent: IMAGE_COMPONENTS.indexOf(component) !== -1,
+  };
+
+  const classes = useUtilityClasses(styleProps);
+
   return (
-    <Component
-      className={clsx(
-        classes.root,
-        {
-          [classes.media]: isMediaComponent,
-          [classes.img]: ['picture', 'img'].indexOf(Component) !== -1,
-        },
-        className,
-      )}
+    <CardMediaRoot
+      className={clsx(classes.root, className)}
+      as={component}
       ref={ref}
       style={composedStyle}
+      styleProps={styleProps}
       src={isMediaComponent ? image || src : undefined}
       {...other}
     >
       {children}
-    </Component>
+    </CardMediaRoot>
   );
 });
 
@@ -106,6 +132,10 @@ CardMedia.propTypes = {
    * @ignore
    */
   style: PropTypes.object,
+  /**
+   * The system prop that allows defining system overrides as well as additional CSS styles.
+   */
+  sx: PropTypes.object,
 };
 
-export default withStyles(styles, { name: 'MuiCardMedia' })(CardMedia);
+export default CardMedia;
diff --git a/packages/material-ui/src/CardMedia/CardMedia.test.js b/packages/material-ui/src/CardMedia/CardMedia.test.js
index 2d6e8c93306dda..8cbba8334d5094 100644
--- a/packages/material-ui/src/CardMedia/CardMedia.test.js
+++ b/packages/material-ui/src/CardMedia/CardMedia.test.js
@@ -1,23 +1,23 @@
 import * as React from 'react';
 import PropTypes from 'prop-types';
 import { expect } from 'chai';
-import { getClasses, createMount, createClientRender, describeConformance } from 'test/utils';
+import { createMount, createClientRender, describeConformanceV5 } from 'test/utils';
 import CardMedia from './CardMedia';
+import classes from './cardMediaClasses';
 
 describe('<CardMedia />', () => {
   const mount = createMount();
-  let classes;
   const render = createClientRender();
-  before(() => {
-    classes = getClasses(<CardMedia image="/fake.png" />);
-  });
 
-  describeConformance(<CardMedia image="/fake.png" />, () => ({
+  describeConformanceV5(<CardMedia image="/fake.png" />, () => ({
     classes,
     inheritComponent: 'div',
     mount,
+    muiName: 'MuiCardMedia',
     refInstanceof: window.HTMLDivElement,
     testComponentPropWith: 'span',
+    testVariantProps: { variant: 'foo' },
+    skip: ['componentsProp'],
   }));
 
   it('should have the backgroundImage specified', () => {
@@ -79,7 +79,7 @@ describe('<CardMedia />', () => {
 
     it('warns when neither `children`, nor `image`, nor `src`, nor `component` are provided', () => {
       expect(() => {
-        PropTypes.checkPropTypes(CardMedia.Naked.propTypes, { classes: {} }, 'prop', 'MockedName');
+        PropTypes.checkPropTypes(CardMedia.propTypes, { classes: {} }, 'prop', 'MockedName');
       }).toErrorDev(
         'Material-UI: Either `children`, `image`, `src` or `component` prop must be specified.',
       );
diff --git a/packages/material-ui/src/CardMedia/cardMediaClasses.d.ts b/packages/material-ui/src/CardMedia/cardMediaClasses.d.ts
new file mode 100644
index 00000000000000..4bf7f3f94b9a98
--- /dev/null
+++ b/packages/material-ui/src/CardMedia/cardMediaClasses.d.ts
@@ -0,0 +1,11 @@
+export interface CardMediaClasses {
+  root: string;
+  media: string;
+  img: string;
+}
+
+declare const cardMediaClasses: CardMediaClasses;
+
+export function getCardMediaUtilityClass(slot: string): string;
+
+export default cardMediaClasses;
diff --git a/packages/material-ui/src/CardMedia/cardMediaClasses.js b/packages/material-ui/src/CardMedia/cardMediaClasses.js
new file mode 100644
index 00000000000000..5a1f4587377c8b
--- /dev/null
+++ b/packages/material-ui/src/CardMedia/cardMediaClasses.js
@@ -0,0 +1,9 @@
+import { generateUtilityClass, generateUtilityClasses } from '@material-ui/unstyled';
+
+export function getCardMediaUtilityClass(slot) {
+  return generateUtilityClass('MuiCardMedia', slot);
+}
+
+const cardMediaClasses = generateUtilityClasses('MuiCardMedia', ['root', 'media', 'img']);
+
+export default cardMediaClasses;
diff --git a/packages/material-ui/src/CardMedia/index.d.ts b/packages/material-ui/src/CardMedia/index.d.ts
index e01400dab1b601..c61f21cc6b4d84 100644
--- a/packages/material-ui/src/CardMedia/index.d.ts
+++ b/packages/material-ui/src/CardMedia/index.d.ts
@@ -1,2 +1,5 @@
 export { default } from './CardMedia';
 export * from './CardMedia';
+
+export { default as cardMediaClasses } from './cardMediaClasses';
+export * from './cardMediaClasses';
diff --git a/packages/material-ui/src/CardMedia/index.js b/packages/material-ui/src/CardMedia/index.js
index 52c81c17a543a3..b20f3170c16b8a 100644
--- a/packages/material-ui/src/CardMedia/index.js
+++ b/packages/material-ui/src/CardMedia/index.js
@@ -1 +1,4 @@
 export { default } from './CardMedia';
+
+export { default as cardMediaClasses } from './cardMediaClasses';
+export * from './cardMediaClasses';