From 46c5deca8b0471db7f54597fb9c451ff3c066d14 Mon Sep 17 00:00:00 2001 From: Robert Allaway Date: Wed, 25 Aug 2021 10:27:06 -0700 Subject: [PATCH] v1.0.1 new manifest types added --- nfti.jsonld | 10427 ++++++++++++++++++++++++++++++++++++++++++++++++++ 1 file changed, 10427 insertions(+) create mode 100644 nfti.jsonld diff --git a/nfti.jsonld b/nfti.jsonld new file mode 100644 index 00000000..cfd588b7 --- /dev/null +++ b/nfti.jsonld @@ -0,0 +1,10427 @@ +{ + "@context": { + "bts": "http://schema.biothings.io/", + "rdf": "http://www.w3.org/1999/02/22-rdf-syntax-ns#", + "rdfs": "http://www.w3.org/2000/01/rdf-schema#", + "schema": "http://schema.org/", + "xsd": "http://www.w3.org/2001/XMLSchema#" + }, + "@graph": [ + { + "@id": "schema:Text", + "@type": [ + "schema:DataType", + "rdfs:Class" + ], + "rdfs:comment": "Data type: Text.", + "rdfs:label": "Text" + }, + { + "@id": "schema:Number", + "@type": [ + "schema:DataType", + "rdfs:Class" + ], + "rdfs:comment": "Data type: Number.", + "rdfs:label": "Number" + }, + { + "@id": "schema:Integer", + "@type": "rdfs:Class", + "rdfs:comment": "Data type: Integer.", + "rdfs:label": "Integer", + "rdfs:subClassOf": { + "@id": "schema:Number" + } + }, + { + "@id": "schema:Thing", + "@type": "rdfs:Class", + "rdfs:comment": "Thing", + "rdfs:label": "Thing", + "schema:isPartOf": { + "@id": "http://schema.org" + } + }, + { + "@id": "bts:BiologicalEntity", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "BiologicalEntity", + "rdfs:subClassOf": { + "@id": "schema:Thing" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:OntologyClass", + "@type": "rdfs:Class", + "rdfs:comment": "a concept or class in an ontology, vocabulary or thesaurus", + "rdfs:label": "OntologyClass", + "rdfs:subClassOf": { + "@id": "schema:Thing" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:RelationshipType", + "@type": "rdfs:Class", + "rdfs:comment": "An OWL property used as an edge label", + "rdfs:label": "RelationshipType", + "rdfs:subClassOf": { + "@id": "bts:OntologyClass" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:GeneOntologyClass", + "@type": "rdfs:Class", + "rdfs:comment": "an ontology class that describes a functional aspect of a gene, gene prodoct or complex", + "rdfs:label": "GeneOntologyClass", + "rdfs:subClassOf": { + "@id": "bts:OntologyClass" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:OrganismTaxon", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "OrganismTaxon", + "rdfs:subClassOf": { + "@id": "bts:OntologyClass" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:OrganismalEntity", + "@type": "rdfs:Class", + "rdfs:comment": "A named entity that is either a part of an organism, a whole organism, population or clade of organisms, excluding molecular entities", + "rdfs:label": "OrganismalEntity", + "rdfs:subClassOf": { + "@id": "bts:BiologicalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:IndividualOrganism", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "IndividualOrganism", + "rdfs:subClassOf": { + "@id": "bts:OrganismalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Case", + "@type": "rdfs:Class", + "rdfs:comment": "An individual organism that has a patient role in some clinical context.", + "rdfs:label": "Case", + "rdfs:subClassOf": { + "@id": "bts:IndividualOrganism" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:PopulationOfIndividualOrganisms", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "PopulationOfIndividualOrganisms", + "rdfs:subClassOf": { + "@id": "bts:OrganismalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Biosample", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "Biosample", + "rdfs:subClassOf": { + "@id": "bts:OrganismalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:DiseaseOrPhenotypicFeature", + "@type": "rdfs:Class", + "rdfs:comment": "Either one of a disease or an individual phenotypic feature. Some knowledge resources such as Monarch treat these as distinct, others such as MESH conflate.", + "rdfs:label": "DiseaseOrPhenotypicFeature", + "rdfs:subClassOf": { + "@id": "bts:BiologicalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Disease", + "@type": "rdfs:Class", + "rdfs:comment": "The diseases of the banked specimens, if applicable.", + "rdfs:label": "Disease", + "rdfs:subClassOf": [ + { + "@id": "bts:Biobank" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Neurofibromatosistype1" + }, + { + "@id": "bts:Neurofibromatosistype2" + }, + { + "@id": "bts:Schwannomatosis" + }, + { + "@id": "bts:Noknowndisease" + }, + { + "@id": "bts:Neurofibromatosistype1" + }, + { + "@id": "bts:Neurofibromatosistype2" + }, + { + "@id": "bts:Schwannomatosis" + }, + { + "@id": "bts:Neurofibromatosistype1" + }, + { + "@id": "bts:Neurofibromatosistype2" + }, + { + "@id": "bts:Schwannomatosis" + } + ], + "sms:displayName": "disease", + "sms:required": "sms:true", + "sms:validationRules": [ + "list" + ] + }, + { + "@id": "bts:PhenotypicFeature", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "PhenotypicFeature", + "rdfs:subClassOf": { + "@id": "bts:DiseaseOrPhenotypicFeature" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Environment", + "@type": "rdfs:Class", + "rdfs:comment": "A feature of the environment of an organism that influences one or more phenotypic features of that organism, potentially mediated by genes", + "rdfs:label": "Environment", + "rdfs:subClassOf": { + "@id": "bts:BiologicalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:InformationContentEntity", + "@type": "rdfs:Class", + "rdfs:comment": "a piece of information that typically describes some piece of biology or is used as support.", + "rdfs:label": "InformationContentEntity", + "rdfs:subClassOf": { + "@id": "schema:Thing" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:ConfidenceLevel", + "@type": "rdfs:Class", + "rdfs:comment": "Level of confidence in a statement", + "rdfs:label": "ConfidenceLevel", + "rdfs:subClassOf": { + "@id": "bts:InformationContentEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:EvidenceType", + "@type": "rdfs:Class", + "rdfs:comment": "Class of evidence that supports an association", + "rdfs:label": "EvidenceType", + "rdfs:subClassOf": { + "@id": "bts:InformationContentEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Publication", + "@type": "rdfs:Class", + "rdfs:comment": "Initial publication associated with the resource.", + "rdfs:label": "Publication", + "rdfs:subClassOf": [ + { + "@id": "bts:Component" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "publication", + "sms:required": "sms:false", + "sms:requiresDependency": [ + { + "@id": "bts:PublicationId" + }, + { + "@id": "bts:PublicationTitle" + }, + { + "@id": "bts:Authors" + }, + { + "@id": "bts:Abstract" + }, + { + "@id": "bts:Journal" + }, + { + "@id": "bts:PublicationDate" + }, + { + "@id": "bts:Pmid" + }, + { + "@id": "bts:Doi" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:MolecularEntity", + "@type": "rdfs:Class", + "rdfs:comment": "A gene, gene product, small molecule or macromolecule (including protein complex)", + "rdfs:label": "MolecularEntity", + "rdfs:subClassOf": { + "@id": "bts:BiologicalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:ChemicalSubstance", + "@type": "rdfs:Class", + "rdfs:comment": "May be a chemical entity or a formulation with a chemical entity as active ingredient, or a complex material with multiple chemical entities as part", + "rdfs:label": "ChemicalSubstance", + "rdfs:subClassOf": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Drug", + "@type": "rdfs:Class", + "rdfs:comment": "A substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease", + "rdfs:label": "Drug", + "rdfs:subClassOf": { + "@id": "bts:ChemicalSubstance" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Metabolite", + "@type": "rdfs:Class", + "rdfs:comment": "Any intermediate or product resulting from metabolism. Includes primary and secondary metabolites.", + "rdfs:label": "Metabolite", + "rdfs:subClassOf": { + "@id": "bts:ChemicalSubstance" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:AnatomicalEntity", + "@type": "rdfs:Class", + "rdfs:comment": "A subcellular location, cell type or gross anatomical part", + "rdfs:label": "AnatomicalEntity", + "rdfs:subClassOf": { + "@id": "bts:OrganismalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:LifeStage", + "@type": "rdfs:Class", + "rdfs:comment": "A stage of development or growth of an organism, including post-natal adult stages", + "rdfs:label": "LifeStage", + "rdfs:subClassOf": { + "@id": "bts:OrganismalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:PlanetaryEntity", + "@type": "rdfs:Class", + "rdfs:comment": "Any entity or process that exists at the level of the whole planet", + "rdfs:label": "PlanetaryEntity", + "rdfs:subClassOf": { + "@id": "schema:Thing" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:EnvironmentalProcess", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "EnvironmentalProcess", + "rdfs:subClassOf": { + "@id": "bts:PlanetaryEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:EnvironmentalFeature", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "EnvironmentalFeature", + "rdfs:subClassOf": { + "@id": "bts:PlanetaryEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:ClinicalEntity", + "@type": "rdfs:Class", + "rdfs:comment": "Any entity or process that exists in the clinical domain and outside the biological realm. Diseases are placed under biological entities", + "rdfs:label": "ClinicalEntity", + "rdfs:subClassOf": { + "@id": "schema:Thing" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:ClinicalTrial", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "ClinicalTrial", + "rdfs:subClassOf": { + "@id": "bts:ClinicalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:ClinicalIntervention", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "ClinicalIntervention", + "rdfs:subClassOf": { + "@id": "bts:ClinicalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Device", + "@type": "rdfs:Class", + "rdfs:comment": "A thing made or adapted for a particular purpose, especially a piece of mechanical or electronic equipment", + "rdfs:label": "Device", + "rdfs:subClassOf": { + "@id": "schema:Thing" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:GenomicEntity", + "@type": "rdfs:Class", + "rdfs:comment": "an entity that can either be directly located on a genome (gene, transcript, exon, regulatory region) or is encoded in a genome (protein)", + "rdfs:label": "GenomicEntity", + "rdfs:subClassOf": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Genome", + "@type": "rdfs:Class", + "rdfs:comment": "A genome is the sum of genetic material within a cell or virion.", + "rdfs:label": "Genome", + "rdfs:subClassOf": { + "@id": "bts:GenomicEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Transcript", + "@type": "rdfs:Class", + "rdfs:comment": "An RNA synthesized on a DNA or RNA template by an RNA polymerase", + "rdfs:label": "Transcript", + "rdfs:subClassOf": { + "@id": "bts:GenomicEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Exon", + "@type": "rdfs:Class", + "rdfs:comment": "A region of the transcript sequence within a gene which is not removed from the primary RNA transcript by RNA splicing", + "rdfs:label": "Exon", + "rdfs:subClassOf": { + "@id": "bts:GenomicEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:CodingSequence", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "CodingSequence", + "rdfs:subClassOf": { + "@id": "bts:GenomicEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:MacromolecularMachine", + "@type": "rdfs:Class", + "rdfs:comment": "A union of gene, gene product, and macromolecular complex. These are the basic units of function in a cell. They either carry out individual biological activities, or they encode molecules which do this.", + "rdfs:label": "MacromolecularMachine", + "rdfs:subClassOf": { + "@id": "bts:GenomicEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:GeneOrGeneProduct", + "@type": "rdfs:Class", + "rdfs:comment": "a union of genes or gene products. Frequently an identifier for one will be used as proxy for another", + "rdfs:label": "GeneOrGeneProduct", + "rdfs:subClassOf": { + "@id": "bts:MacromolecularMachine" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Gene", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "Gene", + "rdfs:subClassOf": { + "@id": "bts:GeneOrGeneProduct" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:GeneProduct", + "@type": "rdfs:Class", + "rdfs:comment": "The functional molecular product of a single gene. Gene products are either proteins or functional RNA molecules", + "rdfs:label": "GeneProduct", + "rdfs:subClassOf": { + "@id": "bts:GeneOrGeneProduct" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Protein", + "@type": "rdfs:Class", + "rdfs:comment": "A gene product that is composed of a chain of amino acid sequences and is produced by ribosome-mediated translation of mRNA", + "rdfs:label": "Protein", + "rdfs:subClassOf": { + "@id": "bts:GeneProduct" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:GeneProductIsoform", + "@type": "rdfs:Class", + "rdfs:comment": "This is an abstract class that can be mixed in with different kinds of gene products to indicate that the gene product is intended to represent a specific isoform rather than a canonical or reference or generic product. The designation of canonical or reference may be arbitrary, or it may represent the superclass of all isoforms.", + "rdfs:label": "GeneProductIsoform", + "rdfs:subClassOf": { + "@id": "bts:GeneProduct" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:ProteinIsoform", + "@type": "rdfs:Class", + "rdfs:comment": "Represents a protein that is a specific isoform of the canonical or reference protein. See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114032/", + "rdfs:label": "ProteinIsoform", + "rdfs:subClassOf": { + "@id": "bts:Protein" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:RnaProduct", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "RnaProduct", + "rdfs:subClassOf": { + "@id": "bts:GeneProduct" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:RnaProductIsoform", + "@type": "rdfs:Class", + "rdfs:comment": "Represents a protein that is a specific isoform of the canonical or reference RNA", + "rdfs:label": "RnaProductIsoform", + "rdfs:subClassOf": { + "@id": "bts:RnaProduct" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:NoncodingRnaProduct", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "NoncodingRnaProduct", + "rdfs:subClassOf": { + "@id": "bts:RnaProduct" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Microrna", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "Microrna", + "rdfs:subClassOf": { + "@id": "bts:NoncodingRnaProduct" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:MacromolecularComplex", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "MacromolecularComplex", + "rdfs:subClassOf": { + "@id": "bts:MacromolecularMachine" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:GeneFamily", + "@type": "rdfs:Class", + "rdfs:comment": "any grouping of multiple genes or gene products related by common descent", + "rdfs:label": "GeneFamily", + "rdfs:subClassOf": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Genotype", + "@type": "rdfs:Class", + "rdfs:comment": "Genotype for the mutated gene.", + "rdfs:label": "Genotype", + "rdfs:subClassOf": [ + { + "@id": "bts:Mutation" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:-/-" + }, + { + "@id": "bts:+/-" + }, + { + "@id": "bts:+/+" + }, + { + "@id": "bts:Unknown" + } + ], + "sms:displayName": "genotype", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Haplotype", + "@type": "rdfs:Class", + "rdfs:comment": "A set of zero or more Alleles on a single instance of a Sequence[VMC]", + "rdfs:label": "Haplotype", + "rdfs:subClassOf": { + "@id": "bts:GenomicEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:SequenceVariant", + "@type": "rdfs:Class", + "rdfs:comment": "An allele that varies in its sequence from what is considered the reference allele at that locus.", + "rdfs:label": "SequenceVariant", + "rdfs:subClassOf": { + "@id": "bts:GenomicEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:DrugExposure", + "@type": "rdfs:Class", + "rdfs:comment": "A drug exposure is an intake of a particular chemical substance", + "rdfs:label": "DrugExposure", + "rdfs:subClassOf": { + "@id": "bts:Environment" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Treatment", + "@type": "rdfs:Class", + "rdfs:comment": "A treatment is targeted at a disease or phenotype and may involve multiple drug 'exposures'", + "rdfs:label": "Treatment", + "rdfs:subClassOf": { + "@id": "bts:Environment" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:GeographicLocation", + "@type": "rdfs:Class", + "rdfs:comment": "a location that can be described in lat/long coordinates", + "rdfs:label": "GeographicLocation", + "rdfs:subClassOf": { + "@id": "bts:PlanetaryEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:GeographicLocationAtTime", + "@type": "rdfs:Class", + "rdfs:comment": "a location that can be described in lat/long coordinates, for a particular time", + "rdfs:label": "GeographicLocationAtTime", + "rdfs:subClassOf": { + "@id": "bts:GeographicLocation" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Occurrent", + "@type": "rdfs:Class", + "rdfs:comment": "A processual entity", + "rdfs:label": "Occurrent", + "rdfs:subClassOf": { + "@id": "schema:Thing" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:BiologicalProcessOrActivity", + "@type": "rdfs:Class", + "rdfs:comment": "Either an individual molecular activity, or a collection of causally connected molecular activities", + "rdfs:label": "BiologicalProcessOrActivity", + "rdfs:subClassOf": { + "@id": "bts:BiologicalEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:MolecularActivity", + "@type": "rdfs:Class", + "rdfs:comment": "An execution of a molecular function carried out by a gene product or macromolecular complex.", + "rdfs:label": "MolecularActivity", + "rdfs:subClassOf": { + "@id": "bts:BiologicalProcessOrActivity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:ActivityAndBehavior", + "@type": "rdfs:Class", + "rdfs:comment": "Activity or behavior of any independent integral living, organization or mechanical actor in the world", + "rdfs:label": "ActivityAndBehavior", + "rdfs:subClassOf": { + "@id": "bts:Occurrent" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Procedure", + "@type": "rdfs:Class", + "rdfs:comment": "A series of actions conducted in a certain order or manner", + "rdfs:label": "Procedure", + "rdfs:subClassOf": { + "@id": "bts:Occurrent" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Phenomenon", + "@type": "rdfs:Class", + "rdfs:comment": "a fact or situation that is observed to exist or happen, especially one whose cause or explanation is in question", + "rdfs:label": "Phenomenon", + "rdfs:subClassOf": { + "@id": "bts:Occurrent" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:BiologicalProcess", + "@type": "rdfs:Class", + "rdfs:comment": "One or more causally connected executions of molecular functions", + "rdfs:label": "BiologicalProcess", + "rdfs:subClassOf": { + "@id": "bts:BiologicalProcessOrActivity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:Pathway", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "Pathway", + "rdfs:subClassOf": { + "@id": "bts:BiologicalProcess" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + } + }, + { + "@id": "bts:PhysiologicalProcess", + "@type": "rdfs:Class", + "rdfs:comment": null, + "rdfs:label": "PhysiologicalProcess", + "rdfs:subClassOf": 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"@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:affectsExpressionOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one changes the level of expression of the other within a system of interest", + "rdfs:label": "affectsExpressionOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:GenomicEntity" + } + }, + { + "@id": "bts:increasesExpressionOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the level of expression of the other within a system of interest", + "rdfs:label": "increasesExpressionOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:GenomicEntity" + } + }, + { + "@id": 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between two molecular entities where the action or effect of one increases the rate or quality of folding of the other ", + "rdfs:label": "increasesFoldingOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:decreasesFoldingOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the rate or quality of folding of the other ", + "rdfs:label": "decreasesFoldingOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:affectsLocalizationOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one changes the localization of the other within a system of interest", + "rdfs:label": "affectsLocalizationOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:increasesLocalizationOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the proper localization of the other within a system of interest", + "rdfs:label": "increasesLocalizationOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:decreasesLocalizationOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the proper localization of the other within a system of interest", + 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"increasesMetabolicProcessingOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:decreasesMetabolicProcessingOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the rate of metabolic processing of the other within a system of interest", + "rdfs:label": "decreasesMetabolicProcessingOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:affectsMolecularModificationOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one leads changes in the molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)", + "rdfs:label": "affectsMolecularModificationOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:increasesMolecularModificationOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one leads to increased molecular modification(s) of the other (e.g. via post-translational modifications of proteins such as the addition of phosphoryl group, or via redox reaction that adds or subtracts electrons)", + "rdfs:label": "increasesMolecularModificationOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" 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"http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:increasesSynthesisOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the rate of chemical synthesis of the other", + "rdfs:label": "increasesSynthesisOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:decreasesSynthesisOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one decreases the rate of chemical synthesis of the other", + "rdfs:label": "decreasesSynthesisOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:affectsDegradationOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one impacts the rate of degradation of the other within a system of interest", + "rdfs:label": "affectsDegradationOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:increasesDegradationOf", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the rate of degradation of the other within a system of interest", + "rdfs:label": "increasesDegradationOf", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:decreasesDegradationOf", 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"@id": "bts:affectsResponseTo", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one impacts the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine, biological or pathological process) to the other", + "rdfs:label": "affectsResponseTo", + "schema:domainIncludes": { + "@id": "bts:MolecularEntity" + }, + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": { + "@id": "bts:MolecularEntity" + } + }, + { + "@id": "bts:increasesResponseTo", + "@type": "rdf:Property", + "rdfs:comment": "holds between two molecular entities where the action or effect of one increases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine, biological or pathological process) to the other", + "rdfs:label": "increasesResponseTo", + "schema:domainIncludes": { + "@id": 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"Name of the main gene insert in the plasmid.", + "rdfs:label": "InsertName", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "insertName", + "sms:required": "sms:true", + "sms:validationRules": [] + }, + { + "@id": "bts:AltInsertName", + "@type": "rdfs:Class", + "rdfs:comment": "Any alternate names of the gene insert.", + "rdfs:label": "AltInsertName", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "altInsertName", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:InsertEntrezId", + "@type": "rdfs:Class", + "rdfs:comment": "The entrez gene id for the gene insert", + "rdfs:label": "InsertEntrezId", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "insertEntrezId", + "sms:required": "sms:true", + "sms:validationRules": [] + }, + { + "@id": "bts:GRNAshRNAsequence", + "@type": "rdfs:Class", + "rdfs:comment": "The sequence of the gRNA and shRNA for the gene insert.", + "rdfs:label": "GRNAshRNAsequence", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "gRNAshRNAsequence", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:InsertSize", + "@type": "rdfs:Class", + "rdfs:comment": "Size, in bp, of the gene insert as it is in the plasmid.", + "rdfs:label": "InsertSize", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "insertSize", + "sms:required": "sms:true", + "sms:validationRules": [] + }, + { + "@id": "bts:InsertSpecies", + "@type": "rdfs:Class", + "rdfs:comment": "Species of the insert", + "rdfs:label": "InsertSpecies", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "insertSpecies", + "sms:required": "sms:true", + "sms:validationRules": [] + }, + { + "@id": "bts:NTerminalTag", + "@type": "rdfs:Class", + "rdfs:comment": "Any tags on the N terminal 5' end of the gene insert in the plasmid. Only tags that are in frame", + "rdfs:label": "NTerminalTag", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "nTerminalTag", + "sms:required": "sms:false", + "sms:validationRules": [ + "list" + ] + }, + { + "@id": "bts:CTerminalTag", + "@type": "rdfs:Class", + "rdfs:comment": "Any tags on the C terminal 3' end of the gene insert in the plasmid. Only tags that are in frame", + "rdfs:label": "CTerminalTag", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "cTerminalTag", + "sms:required": "sms:false", + "sms:validationRules": [ + "list" + ] + }, + { + "@id": "bts:CloningMethod", + "@type": "rdfs:Class", + "rdfs:comment": "How the vector was constructed. (e.g. restriction enzyme, TOPO cloning, etc.)", + "rdfs:label": "CloningMethod", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:RestrictionEnzyme" + }, + { + "@id": "bts:TOPOcloning" + }, + { + "@id": "bts:GatewayCloning" + }, + { + "@id": "bts:LigationIndependentCloning" + }, + { + "@id": "bts:GibsonCloning" + }, + { + "@id": "bts:Unknown" + } + ], + "sms:displayName": "cloningMethod", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:5primeCloningSite", + "@type": "rdfs:Class", + "rdfs:comment": "If Restriction Enzyme was selected as the cloning method, specifies what enzyme was used on the 5' (N-terminal) end of the insert", + "rdfs:label": "5primeCloningSite", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "5primeCloningSite", + "sms:required": "sms:false", + "sms:requiresDependency": [ + { + "@id": "bts:CloningMethod" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:5primeSiteDestroyed", + "@type": "rdfs:Class", + "rdfs:comment": "If 5' site was destroyed during cloning. (e.g. yes, no, unknown).", + "rdfs:label": "5primeSiteDestroyed", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Yes" + }, + { + "@id": "bts:No" + }, + { + "@id": "bts:Unknown" + } + ], + "sms:displayName": "5primeSiteDestroyed", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:3primeCloningSite", + "@type": "rdfs:Class", + "rdfs:comment": "If Restriction Enzyme was selected as the cloning method, specifies what enzyme was used on the 3' (C-terminal) end of the insert", + "rdfs:label": "3primeCloningSite", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "3primeCloningSite", + "sms:required": "sms:false", + "sms:requiresDependency": [ + { + "@id": "bts:CloningMethod" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:3primeSiteDestroyed", + "@type": "rdfs:Class", + "rdfs:comment": "If 3' site was destroyed during cloning. (e.g. yes, no, unknown)", + "rdfs:label": "3primeSiteDestroyed", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Yes" + }, + { + "@id": "bts:No" + }, + { + "@id": "bts:Unknown" + } + ], + "sms:displayName": "3primeSiteDestroyed", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Promoter", + "@type": "rdfs:Class", + "rdfs:comment": "Promoter driving the expression of the insert in the plasmid", + "rdfs:label": "Promoter", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "promoter", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:5primer", + "@type": "rdfs:Class", + "rdfs:comment": "Primer to sequence the 5' end (N-terminal) of the insert", + "rdfs:label": "5primer", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "5primer", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:3primer", + "@type": "rdfs:Class", + "rdfs:comment": "Primer to sequence the 3' end (C-terminal) of the insert.", + "rdfs:label": "3primer", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "3primer", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:VectorBackbone", + "@type": "rdfs:Class", + "rdfs:comment": "Name of the backbone the plasmid is built on. (e.g pGBT9)", + "rdfs:label": "VectorBackbone", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "vectorBackbone", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:VectorType", + "@type": "rdfs:Class", + "rdfs:comment": "Primary function of the plasmid. (e.g. mammalian expression, bacterial expression, etc.)", + "rdfs:label": "VectorType", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:MammalianExpression" + }, + { + "@id": "bts:BacterialExpression" + }, + { + "@id": "bts:Lentiviral" + }, + { + "@id": "bts:Adenoviral" + }, + { + "@id": "bts:AAV" + }, + { + "@id": "bts:RNAi" + }, + { + "@id": "bts:Luciferase" + }, + { + "@id": "bts:Cre/Lox" + }, + { + "@id": "bts:YeastExpression" + }, + { + "@id": "bts:WormExpression" + }, + { + "@id": "bts:InsectExpression" + }, + { + "@id": "bts:PlantExpression" + }, + { + "@id": "bts:MouseTargeting" + }, + { + "@id": "bts:CRISPR" + }, + { + "@id": "bts:TALEN" + }, + { + "@id": "bts:SyntheticBiology" + }, + { + "@id": "bts:Unspecified" + }, + { + "@id": "bts:Other" + } + ], + "sms:displayName": "vectorType", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:BackboneSize", + "@type": "rdfs:Class", + "rdfs:comment": "Size in bp of the backbone without the insert", + "rdfs:label": "BackboneSize", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "backboneSize", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:TotalSize", + "@type": "rdfs:Class", + "rdfs:comment": "Size of vector with insert. Derived from insertSize and backboneSize.", + "rdfs:label": "TotalSize", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "totalSize", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:BacterialResistance", + "@type": "rdfs:Class", + "rdfs:comment": "Antibiotic(s) that should be used for selection in bacteria. (e.g. ampicillin, kanamycin, etc.)", + "rdfs:label": "BacterialResistance", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Ampicillin" + }, + { + "@id": "bts:Kanamycin" + }, + { + "@id": "bts:Chloramphenicol" + }, + { + "@id": "bts:Tetracycline" + }, + { + "@id": "bts:Spectinomycin" + }, + { + "@id": "bts:Hygromycin" + }, + { + "@id": "bts:Bleocin(Zeocin)" + }, + { + "@id": "bts:Gentamycin" + }, + { + "@id": "bts:Streptomycin" + }, + { + "@id": "bts:Nourseothricin(clonNat)" + }, + { + "@id": "bts:AmpicillinandBleocin(Zeocin)" + }, + { + "@id": "bts:AmpicillinandKanamycin" + }, + { + "@id": "bts:AmpicillinandTetracycline" + }, + { + "@id": "bts:AmpicillinandStreptomycin" + }, + { + "@id": "bts:AmpicillinandSpectinomycin" + }, + { + "@id": "bts:ChloramphenicolandAmpicillin" + }, + { + "@id": "bts:ChloramphenicolandBleocin(Zeocin)" + }, + { + "@id": "bts:ChloramphenicolandTetracycline" + }, + { + "@id": "bts:ChloramphenicolandKanamycin" + }, + { + "@id": "bts:ChloramphenicolandSpectinomycin" + }, + { + "@id": "bts:ChloramphenicolandGentamycin" + }, + { + "@id": "bts:SpectinomycinandStreptomycin" + }, + { + "@id": "bts:Other" + } + ], + "sms:displayName": "bacterialResistance", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:SelectableMarker", + "@type": "rdfs:Class", + "rdfs:comment": "Are there any additional selection markers on this plasmid, for example, any mammalian selection markers or fluorescent proteins?", + "rdfs:label": "SelectableMarker", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Neomycin" + }, + { + "@id": "bts:Puromycin" + }, + { + "@id": "bts:Hygromycin" + }, + { + "@id": "bts:Zeocin" + }, + { + "@id": "bts:Blasticidin" + }, + { + "@id": "bts:Gentamicin" + }, + { + "@id": "bts:TRP1" + }, + { + "@id": "bts:LEU1" + }, + { + "@id": "bts:URA3" + }, + { + "@id": "bts:HIS3" + }, + { + "@id": "bts:Basta" + }, + { + "@id": "bts:Other" + } + ], + "sms:displayName": "selectableMarker", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:CopyNumber", + "@type": "rdfs:Class", + "rdfs:comment": "If a plasmid produces a sufficient amount of DNA from a normal miniprep or if plasmid requires special growth conditions or it is difficult to grow. (e.g. high copy, low copy, unknown).", + "rdfs:label": "CopyNumber", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:HighCopy" + }, + { + "@id": "bts:LowCopy" + }, + { + "@id": "bts:Unknown" + } + ], + "sms:displayName": "copyNumber", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:GrowthTemp", + "@type": "rdfs:Class", + "rdfs:comment": "At what temperature should the bacteria hosting the plasmid be grown", + "rdfs:label": "GrowthTemp", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:37C" + }, + { + "@id": "bts:30C" + }, + { + "@id": "bts:RoomTemperature" + } + ], + "sms:displayName": "growthTemp", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:GrowthStrain", + "@type": "rdfs:Class", + "rdfs:comment": "The E.Coli strain that should be used to distribute the plasmid. (e.g. DH5alpha, NEB Stable, etc.)", + "rdfs:label": "GrowthStrain", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:DH5alpha" + }, + { + "@id": "bts:NEBStable" + }, + { + "@id": "bts:CcdbSurvival" + }, + { + "@id": "bts:Pir1" + }, + { + "@id": "bts:Other" + } + ], + "sms:displayName": "growthStrain", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Hazardous", + "@type": "rdfs:Class", + "rdfs:comment": "Does the unmodified plasmid DNA, either in purified form or when introduced into bacterial or mammalian cells require handling at Biosafety Level 2 or higher?", + "rdfs:label": "Hazardous", + "rdfs:subClassOf": [ + { + "@id": "bts:GeneticReagent" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Yes" + }, + { + "@id": "bts:No" + }, + { + "@id": "bts:Unknown" + } + ], + "sms:displayName": "hazardous", + "sms:required": "sms:true", + "sms:validationRules": [] + }, + { + "@id": "bts:Donor", + "@type": "rdfs:Class", + "rdfs:comment": "A person, animal, etc. who is the contributor of the resource.", + "rdfs:label": "Donor", + "rdfs:subClassOf": [ + { + "@id": "bts:Component" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "donor", + "sms:required": "sms:false", + "sms:requiresDependency": [ + { + "@id": "bts:DonorId" + }, + { + "@id": "bts:ParentDonorId" + }, + { + "@id": "bts:Species" + }, + { + "@id": "bts:Breed" + }, + { + "@id": "bts:Strain" + }, + { + "@id": "bts:Sex" + }, + { + "@id": "bts:Age" + }, + { + "@id": "bts:Race" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:DonorId", + "@type": "rdfs:Class", + "rdfs:comment": "A uniqe identifier for donor.", + "rdfs:label": "DonorId", + "rdfs:subClassOf": [ + { + "@id": "bts:Donor" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "donorId", + "sms:required": "sms:true", + "sms:validationRules": [] + }, + { + "@id": "bts:ParentDonorId", + "@type": "rdfs:Class", + "rdfs:comment": "The ID of the parent donor.", + "rdfs:label": "ParentDonorId", + "rdfs:subClassOf": [ + { + "@id": "bts:Donor" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "parentDonorId", + "sms:required": "sms:false", + "sms:requiresDependency": [ + { + "@id": "bts:DonorId" + } + ], + "sms:validationRules": [] + }, + { + "@id": "bts:Species", + "@type": "rdfs:Class", + "rdfs:comment": "The species of the individual the resource was derived from.", + "rdfs:label": "Species", + "rdfs:subClassOf": [ + { + "@id": "bts:Donor" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Homosapiens" + }, + { + "@id": "bts:Musmusculus" + }, + { + "@id": "bts:Musmusculus(humanized)" + }, + { + "@id": "bts:Rattusnorvegicus" + }, + { + "@id": "bts:Drosophilamelanogaster" + }, + { + "@id": "bts:Rhesusmacaque" + }, + { + "@id": "bts:Pantroglodytes" + }, + { + "@id": "bts:Gallusgallus" + }, + { + "@id": "bts:Susscrofa" + }, + { + "@id": "bts:Oryctolaguscuniculus" + }, + { + "@id": "bts:Daniorerio" + } + ], + "sms:displayName": "species", + "sms:required": "sms:true", + "sms:validationRules": [] + }, + { + "@id": "bts:Breed", + "@type": "rdfs:Class", + "rdfs:comment": "The breed/subspecies of the indivudal the resource was derived from.", + "rdfs:label": "Breed", + "rdfs:subClassOf": [ + { + "@id": "bts:Donor" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "breed", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Strain", + "@type": "rdfs:Class", + "rdfs:comment": "The strain from which the resource was derived from.", + "rdfs:label": "Strain", + "rdfs:subClassOf": [ + { + "@id": "bts:Donor" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "strain", + "sms:required": "sms:false", + "sms:validationRules": [] + }, + { + "@id": "bts:Sex", + "@type": "rdfs:Class", + "rdfs:comment": "The sex of the indiviudal from which the resource was derived from.", + "rdfs:label": "Sex", + "rdfs:subClassOf": [ + { + "@id": "bts:Donor" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "schema:rangeIncludes": [ + { + "@id": "bts:Male" + }, + { + "@id": "bts:Female" + }, + { + "@id": "bts:Unknown" + } + ], + "sms:displayName": "sex", + "sms:required": "sms:true", + "sms:validationRules": [] + }, + { + "@id": "bts:Age", + "@type": "rdfs:Class", + "rdfs:comment": "That age of the individual from which the resource was derived from.", + "rdfs:label": "Age", + "rdfs:subClassOf": [ + { + "@id": "bts:Donor" + } + ], + "schema:isPartOf": { + "@id": "http://schema.biothings.io" + }, + "sms:displayName": "age", + "sms:required": 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