From 5f06daf2cac6bde52ec79a7200fa1d3cc3934f3e Mon Sep 17 00:00:00 2001 From: Caroline Eastwood Date: Tue, 5 Nov 2024 11:29:00 +0000 Subject: [PATCH] Fixes #2673 Added a New term with textual and logical defs, extended description, references and synonyms --- src/ontology/cl-edit.owl | 30 ++++++++++++++++++++++-------- 1 file changed, 22 insertions(+), 8 deletions(-) diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl index f6e9c9ec3..ce84a69a2 100644 --- a/src/ontology/cl-edit.owl +++ b/src/ontology/cl-edit.owl @@ -3087,8 +3087,8 @@ Declaration(Class(obo:CL_4047011)) Declaration(Class(obo:CL_4047012)) Declaration(Class(obo:CL_4047018)) Declaration(Class(obo:CL_4047019)) -Declaration(Class(obo:CL_4047025)) Declaration(Class(obo:CL_4047023)) +Declaration(Class(obo:CL_4047025)) Declaration(Class(obo:CL_4047051)) Declaration(Class(obo:CL_4047052)) Declaration(Class(obo:CL_4047101)) @@ -3115,6 +3115,7 @@ Declaration(Class(obo:CL_4052020)) Declaration(Class(obo:CL_4052021)) Declaration(Class(obo:CL_4052022)) Declaration(Class(obo:CL_4052023)) +Declaration(Class(obo:CL_4052024)) Declaration(Class(obo:CL_4052025)) Declaration(Class(obo:CL_4052048)) Declaration(Class(obo:CL_4052049)) @@ -32724,13 +32725,6 @@ AnnotationAssertion(terms:date obo:CL_4047019 "2024-09-24T12:11:09Z"^^xsd:dateTi AnnotationAssertion(rdfs:label obo:CL_4047019 "early enterocyte"@en) EquivalentClasses(obo:CL_4047019 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013740))) -# Class: obo:CL_4047025 (type G cell of stomach) - -AnnotationAssertion(terms:contributor obo:CL_4047025 ) -AnnotationAssertion(terms:date obo:CL_4047025 "2024-10-24T10:43:22Z"^^xsd:dateTime) -AnnotationAssertion(rdfs:label obo:CL_4047025 "type G cell of stomach"@en) -EquivalentClasses(obo:CL_4047025 ObjectIntersectionOf(obo:CL_0000508 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))) - # Class: obo:CL_4047023 (intestinal lamina propria fibroblast) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21252048") Annotation(oboInOwl:hasDbXref "PMID:36032088") obo:IAO_0000115 obo:CL_4047023 "A fibroblast located in the lamina propria of the intestinal mucosa. This cell expresses PDGFRα and CD81 and is negative for α-smooth muscle actin (α-SMA). This cell is predominantly located in the small intestine adjacent to myofibroblasts surrounding the crypts. It is capable of synthesizing extracellular matrix components and structural proteins such as collagen and elastin.") @@ -32740,6 +32734,13 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30270042") oboInOwl:hasR AnnotationAssertion(rdfs:label obo:CL_4047023 "intestinal lamina propria fibroblast"@en) EquivalentClasses(obo:CL_4047023 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004780) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070278))) +# Class: obo:CL_4047025 (type G cell of stomach) + +AnnotationAssertion(terms:contributor obo:CL_4047025 ) +AnnotationAssertion(terms:date obo:CL_4047025 "2024-10-24T10:43:22Z"^^xsd:dateTime) +AnnotationAssertion(rdfs:label obo:CL_4047025 "type G cell of stomach"@en) +EquivalentClasses(obo:CL_4047025 ObjectIntersectionOf(obo:CL_0000508 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001276))) + # Class: obo:CL_4047051 (small intestine BEST4+ enterocyte) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24223998") Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_4047051 "An enterocyte of the human small intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels. These enterocytes have a disinctive transcriptomic profile and are scattered through the small intestine epithelium.") @@ -33033,6 +33034,19 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:39198675") rdfs:comment AnnotationAssertion(rdfs:label obo:CL_4052023 "luminal endometrial unciliated epithelial cell") EquivalentClasses(obo:CL_4052023 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011949) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032940))) +# Class: obo:CL_4052024 (type IIx muscle cell) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727990") Annotation(oboInOwl:hasDbXref "PMID:35908794") Annotation(oboInOwl:hasDbXref "PMID:36361732") Annotation(oboInOwl:hasDbXref "doi:10.1101/2024.05.15.594276") obo:IAO_0000115 obo:CL_4052024 "A fast type II muscle cell that is part of the skeletal muscle tissue. This cell is characterized by its intermediate metabolic profile, utilizing both glycolytic and oxidative pathways for energy production. In humans, it is distinguished by the expression of myosin heavy chain 1 (MYH1).") +AnnotationAssertion(terms:contributor obo:CL_4052024 ) +AnnotationAssertion(terms:date obo:CL_4052024 "2024-11-04T10:26:29Z"^^xsd:dateTime) +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727990") oboInOwl:hasExactSynonym obo:CL_4052024 "type 2x muscle cell") +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727990") oboInOwl:hasExactSynonym obo:CL_4052024 "type 2x muscle fiber") +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1101/2024.05.15.594276") oboInOwl:hasExactSynonym obo:CL_4052024 "type IIx muscle fiber") +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34727990") rdfs:comment obo:CL_4052024 "In humans, type IIx fiber contains high levels of MYLK2, enhancing contraction speed and force via myosin phosphorylation, especially under low calcium. This mechanism supports post-activation potentiation, increasing force output in fast-twitch muscles. Additionally, this fiber has abundant ACTN3 (α-actinin-3), linked to muscle power, and exhibits the highest shortening velocity among human muscle fiber types.") +AnnotationAssertion(rdfs:label obo:CL_4052024 "type IIx muscle cell") +SubClassOf(obo:CL_4052024 obo:CL_0002212) +SubClassOf(obo:CL_4052024 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001134)) + # Class: obo:CL_4052025 (neuromuscular junction nucleus) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33037211") Annotation(oboInOwl:hasDbXref "PMID:33311457") Annotation(oboInOwl:hasDbXref "PMID:33311464") obo:IAO_0000115 obo:CL_4052025 "A specialized muscle nucleus that is part of an extrafusal muscle fiber, clustered at the postsynaptic side of the neuromuscular junction. This nucleus exhibits a distinct transcriptional profile, including acetylcholine receptor (AChR) subunit genes. It regulates the production of proteins essential for maintaining the structure and function of the neuromuscular junction, supporting efficient nerve-muscle signaling for muscle contraction.")