diff --git a/sdk-extensions/autoconfigure/README.md b/sdk-extensions/autoconfigure/README.md
index 56a446bd18d..65dd75ac01f 100644
--- a/sdk-extensions/autoconfigure/README.md
+++ b/sdk-extensions/autoconfigure/README.md
@@ -40,6 +40,7 @@ environment variables, e.g., `OTEL_TRACES_EXPORTER=zipkin`.
   * [Periodic Metric Reader](#periodic-metric-reader)
   * [Metric exporters](#metric-exporters)
     + [Prometheus exporter](#prometheus-exporter)
+  * [Cardinality limits](#cardinality-limits)
 - [Logger provider](#logger-provider)
 - [Batch log record processor](#batch-log-record-processor)
 - [Customizing the OpenTelemetry SDK](#customizing-the-opentelemetry-sdk)
@@ -319,7 +320,6 @@ The following configuration options are specific to `SdkMeterProvider`. See [gen
 |-----------------------------|-----------------------------|----------------------------------------------------------------------------------------------|
 | otel.metric.export.interval | OTEL_METRIC_EXPORT_INTERVAL | The interval, in milliseconds, between the start of two export attempts. Default is `60000`. |
 
-
 ### Metric exporters
 
 The following exporters are only available for the metric signal. See [exporters](#exporters) for general exporter configuration.
@@ -337,6 +337,12 @@ The [Prometheus](https://github.com/prometheus/docs/blob/master/content/docs/ins
 Note that this is a pull exporter - it opens up a server on the local process listening on the specified host and port, which
 a Prometheus server scrapes from.
 
+### Cardinality Limits
+
+| System property                             | Environment variable                        | Description                                                                                                                               |
+|---------------------------------------------|---------------------------------------------|-------------------------------------------------------------------------------------------------------------------------------------------|
+| otel.experimental.metrics.cardinality.limit | OTEL_EXPERIMENTAL_METRICS_CARDINALITY_LIMIT | If set, configure experimental cardinality limit. The value dictates the maximum number of distinct points per metric. Default is `2000`. |
+
 ## Logger provider
 
 The following configuration options are specific to `SdkLoggerProvider`. See [general configuration](#general-configuration) for general configuration.
diff --git a/sdk-extensions/autoconfigure/src/main/java/io/opentelemetry/sdk/autoconfigure/MeterProviderConfiguration.java b/sdk-extensions/autoconfigure/src/main/java/io/opentelemetry/sdk/autoconfigure/MeterProviderConfiguration.java
index fc168856c84..74727b09444 100644
--- a/sdk-extensions/autoconfigure/src/main/java/io/opentelemetry/sdk/autoconfigure/MeterProviderConfiguration.java
+++ b/sdk-extensions/autoconfigure/src/main/java/io/opentelemetry/sdk/autoconfigure/MeterProviderConfiguration.java
@@ -14,6 +14,7 @@
 import io.opentelemetry.sdk.metrics.export.MetricReader;
 import io.opentelemetry.sdk.metrics.internal.SdkMeterProviderUtil;
 import io.opentelemetry.sdk.metrics.internal.exemplar.ExemplarFilter;
+import io.opentelemetry.sdk.metrics.internal.state.MetricStorage;
 import java.io.Closeable;
 import java.util.Collections;
 import java.util.List;
@@ -49,8 +50,18 @@ static void configureMeterProvider(
         break;
     }
 
+    int cardinalityLimit =
+        config.getInt(
+            "otel.experimental.metrics.cardinality.limit", MetricStorage.DEFAULT_MAX_CARDINALITY);
+    if (cardinalityLimit < 1) {
+      throw new ConfigurationException("otel.experimental.metrics.cardinality.limit must be >= 1");
+    }
+
     configureMetricReaders(config, spiHelper, metricExporterCustomizer, closeables)
-        .forEach(meterProviderBuilder::registerMetricReader);
+        .forEach(
+            reader ->
+                SdkMeterProviderUtil.registerMetricReaderWithCardinalitySelector(
+                    meterProviderBuilder, reader, instrumentType -> cardinalityLimit));
   }
 
   static List<MetricReader> configureMetricReaders(
diff --git a/sdk-extensions/autoconfigure/src/testFullConfig/java/io/opentelemetry/sdk/autoconfigure/MeterProviderConfigurationTest.java b/sdk-extensions/autoconfigure/src/testFullConfig/java/io/opentelemetry/sdk/autoconfigure/MeterProviderConfigurationTest.java
new file mode 100644
index 00000000000..e1ba6000fd5
--- /dev/null
+++ b/sdk-extensions/autoconfigure/src/testFullConfig/java/io/opentelemetry/sdk/autoconfigure/MeterProviderConfigurationTest.java
@@ -0,0 +1,108 @@
+/*
+ * Copyright The OpenTelemetry Authors
+ * SPDX-License-Identifier: Apache-2.0
+ */
+
+package io.opentelemetry.sdk.autoconfigure;
+
+import static org.assertj.core.api.Assertions.as;
+import static org.assertj.core.api.Assertions.assertThat;
+import static org.assertj.core.api.Assertions.assertThatThrownBy;
+
+import com.google.common.collect.ImmutableMap;
+import io.opentelemetry.internal.testing.CleanupExtension;
+import io.opentelemetry.sdk.autoconfigure.internal.SpiHelper;
+import io.opentelemetry.sdk.autoconfigure.spi.ConfigurationException;
+import io.opentelemetry.sdk.autoconfigure.spi.internal.DefaultConfigProperties;
+import io.opentelemetry.sdk.metrics.InstrumentType;
+import io.opentelemetry.sdk.metrics.SdkMeterProvider;
+import io.opentelemetry.sdk.metrics.SdkMeterProviderBuilder;
+import io.opentelemetry.sdk.metrics.export.MetricReader;
+import io.opentelemetry.sdk.metrics.internal.export.CardinalityLimitSelector;
+import java.io.Closeable;
+import java.util.ArrayList;
+import java.util.Collections;
+import java.util.List;
+import org.assertj.core.api.InstanceOfAssertFactories;
+import org.junit.jupiter.api.Test;
+import org.junit.jupiter.api.extension.RegisterExtension;
+
+class MeterProviderConfigurationTest {
+
+  @RegisterExtension CleanupExtension cleanup = new CleanupExtension();
+
+  private final SpiHelper spiHelper =
+      SpiHelper.create(MeterProviderConfigurationTest.class.getClassLoader());
+
+  @Test
+  void configureMeterProvider_InvalidCardinalityLimit() {
+    List<Closeable> closeables = new ArrayList<>();
+
+    assertThatThrownBy(
+            () -> {
+              MeterProviderConfiguration.configureMeterProvider(
+                  SdkMeterProvider.builder(),
+                  DefaultConfigProperties.createForTest(
+                      ImmutableMap.of(
+                          "otel.metrics.exporter",
+                          "logging",
+                          "otel.experimental.metrics.cardinality.limit",
+                          "0")),
+                  spiHelper,
+                  (a, b) -> a,
+                  closeables);
+            })
+        .isInstanceOf(ConfigurationException.class)
+        .hasMessage("otel.experimental.metrics.cardinality.limit must be >= 1");
+    cleanup.addCloseables(closeables);
+  }
+
+  @Test
+  void configureMeterProvider_ConfiguresCardinalityLimit() {
+    List<Closeable> closeables = new ArrayList<>();
+
+    // Verify default cardinality
+    SdkMeterProviderBuilder builder = SdkMeterProvider.builder();
+    MeterProviderConfiguration.configureMeterProvider(
+        builder,
+        DefaultConfigProperties.createForTest(
+            Collections.singletonMap("otel.metrics.exporter", "logging")),
+        spiHelper,
+        (a, b) -> a,
+        closeables);
+    cleanup.addCloseables(closeables);
+    assertCardinalityLimit(builder, 2000);
+
+    // Customized limit cardinality limit to 100
+    builder = SdkMeterProvider.builder();
+    MeterProviderConfiguration.configureMeterProvider(
+        builder,
+        DefaultConfigProperties.createForTest(
+            ImmutableMap.of(
+                "otel.metrics.exporter",
+                "logging",
+                "otel.experimental.metrics.cardinality.limit",
+                "100")),
+        spiHelper,
+        (a, b) -> a,
+        closeables);
+    cleanup.addCloseables(closeables);
+    assertCardinalityLimit(builder, 100);
+  }
+
+  private static void assertCardinalityLimit(
+      SdkMeterProviderBuilder builder, int expectedCardinalityLimit) {
+    assertThat(builder)
+        .extracting(
+            "metricReaders",
+            as(InstanceOfAssertFactories.map(MetricReader.class, CardinalityLimitSelector.class)))
+        .hasSizeGreaterThan(0)
+        .allSatisfy(
+            (metricReader, cardinalityLimitSelector) -> {
+              for (InstrumentType instrumentType : InstrumentType.values()) {
+                assertThat(cardinalityLimitSelector.getCardinalityLimit(instrumentType))
+                    .isEqualTo(expectedCardinalityLimit);
+              }
+            });
+  }
+}