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When calling cooler zoomify with --balance and custom balance args (e.g. --balance-args='--cis-only') using an already balanced matrix as base resolution, no checks are performed to ensure that the base resolution was balanced with the same settings specified through --balance-args.
logger.info(f"Balancing zoom level with bin size {res}")
This can lead to inconsistent balancing (e.g. the base resolution was balanced using genome-wide interactions, while coarser resolutions are balanced with cis interactions only).
The text was updated successfully, but these errors were encountered:
When calling
cooler zoomify
with--balance
and custom balance args (e.g.--balance-args='--cis-only'
) using an already balanced matrix as base resolution, no checks are performed to ensure that the base resolution was balanced with the same settings specified through--balance-args
.cooler/cooler/cli/zoomify.py
Lines 30 to 35 in 6b174f1
This can lead to inconsistent balancing (e.g. the base resolution was balanced using genome-wide interactions, while coarser resolutions are balanced with cis interactions only).
The text was updated successfully, but these errors were encountered: