diff --git a/ddl/db_integration_test.go b/ddl/db_integration_test.go
index 505a44dff3522..4993ed9e84a0e 100644
--- a/ddl/db_integration_test.go
+++ b/ddl/db_integration_test.go
@@ -1556,11 +1556,15 @@ func (s *testIntegrationSuite4) TestAlterColumn(c *C) {
 	createSQL = result.Rows()[0][1]
 	expected = "CREATE TABLE `mc` (\n  `a` bigint(20) NOT NULL AUTO_INCREMENT,\n  `b` int(11) DEFAULT NULL,\n  PRIMARY KEY (`a`)\n) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_bin"
 	c.Assert(createSQL, Equals, expected)
-	s.tk.MustExec("alter table mc modify column a bigint") // Drops auto_increment
+	_, err = s.tk.Exec("alter table mc modify column a bigint") // Droppping auto_increment is not allow when @@tidb_allow_remove_auto_inc == 'off'
+	c.Assert(err, NotNil)
+	s.tk.MustExec("set @@tidb_allow_remove_auto_inc = on")
+	s.tk.MustExec("alter table mc modify column a bigint") // Dropping auto_increment is ok when @@tidb_allow_remove_auto_inc == 'on'
 	result = s.tk.MustQuery("show create table mc")
 	createSQL = result.Rows()[0][1]
 	expected = "CREATE TABLE `mc` (\n  `a` bigint(20) NOT NULL,\n  `b` int(11) DEFAULT NULL,\n  PRIMARY KEY (`a`)\n) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_bin"
 	c.Assert(createSQL, Equals, expected)
+
 	_, err = s.tk.Exec("alter table mc modify column a bigint auto_increment") // Adds auto_increment should throw error
 	c.Assert(err, NotNil)
 
diff --git a/ddl/ddl_api.go b/ddl/ddl_api.go
index 7000afe1fb320..f0438941462f2 100644
--- a/ddl/ddl_api.go
+++ b/ddl/ddl_api.go
@@ -2609,6 +2609,10 @@ func (d *ddl) getModifiableColumnJob(ctx sessionctx.Context, ident ast.Ident, or
 	if !mysql.HasAutoIncrementFlag(col.Flag) && mysql.HasAutoIncrementFlag(newCol.Flag) {
 		return nil, errUnsupportedModifyColumn.GenWithStackByArgs("set auto_increment")
 	}
+	// Disallow modifying column from auto_increment to not auto_increment if the session variable `AllowRemoveAutoInc` is false.
+	if !ctx.GetSessionVars().AllowRemoveAutoInc && mysql.HasAutoIncrementFlag(col.Flag) && !mysql.HasAutoIncrementFlag(newCol.Flag) {
+		return nil, errUnsupportedModifyColumn.GenWithStackByArgs("to remove auto_increment without @@tidb_allow_remove_auto_inc enabled")
+	}
 
 	// We support modifying the type definitions of 'null' to 'not null' now.
 	var modifyColumnTp byte
diff --git a/sessionctx/variable/session.go b/sessionctx/variable/session.go
index 64835a0cc545f..f52decd4a6b2d 100644
--- a/sessionctx/variable/session.go
+++ b/sessionctx/variable/session.go
@@ -401,6 +401,9 @@ type SessionVars struct {
 
 	// DurationCompile is the duration of compiling AST to execution plan of the last query.
 	DurationCompile time.Duration
+
+	// AllowRemoveAutoInc indicates whether a user can drop the auto_increment column attribute or not.
+	AllowRemoveAutoInc bool
 }
 
 // ConnectionInfo present connection used by audit.
@@ -453,6 +456,7 @@ func NewSessionVars() *SessionVars {
 		SlowQueryFile:               config.GetGlobalConfig().Log.SlowQueryFile,
 		WaitSplitRegionFinish:       DefTiDBWaitSplitRegionFinish,
 		WaitSplitRegionTimeout:      DefWaitSplitRegionTimeout,
+		AllowRemoveAutoInc:          DefTiDBAllowRemoveAutoInc,
 	}
 	vars.Concurrency = Concurrency{
 		IndexLookupConcurrency:     DefIndexLookupConcurrency,
@@ -834,6 +838,8 @@ func (s *SessionVars) SetSystemVar(name string, val string) error {
 		s.TxnMode = strings.ToUpper(val)
 	case TiDBLowResolutionTSO:
 		s.LowResolutionTSO = TiDBOptOn(val)
+	case TiDBAllowRemoveAutoInc:
+		s.AllowRemoveAutoInc = TiDBOptOn(val)
 	}
 	s.systems[name] = val
 	return nil
diff --git a/sessionctx/variable/sysvar.go b/sessionctx/variable/sysvar.go
index 233484f99af45..c5632cf987e80 100644
--- a/sessionctx/variable/sysvar.go
+++ b/sessionctx/variable/sysvar.go
@@ -701,6 +701,7 @@ var defaultSysVars = []*SysVar{
 	{ScopeSession, TiDBWaitSplitRegionTimeout, strconv.Itoa(DefWaitSplitRegionTimeout)},
 	{ScopeSession, TiDBLowResolutionTSO, "0"},
 	{ScopeSession, TiDBExpensiveQueryTimeThreshold, strconv.Itoa(DefTiDBExpensiveQueryTimeThreshold)},
+	{ScopeSession, TiDBAllowRemoveAutoInc, BoolToIntStr(DefTiDBAllowRemoveAutoInc)},
 }
 
 // SynonymsSysVariables is synonyms of system variables.
diff --git a/sessionctx/variable/tidb_vars.go b/sessionctx/variable/tidb_vars.go
index 002ebf722b38a..46ebb8b17c8cb 100644
--- a/sessionctx/variable/tidb_vars.go
+++ b/sessionctx/variable/tidb_vars.go
@@ -142,6 +142,9 @@ const (
 
 	// TiDBLowResolutionTSO is used for reading data with low resolution TSO which is updated once every two seconds
 	TiDBLowResolutionTSO = "tidb_low_resolution_tso"
+
+	// TiDBAllowRemoveAutoInc indicates whether a user can drop the auto_increment column attribute or not.
+	TiDBAllowRemoveAutoInc = "tidb_allow_remove_auto_inc"
 )
 
 // TiDB system variable names that both in session and global scope.
@@ -344,6 +347,7 @@ const (
 	DefTiDBWaitSplitRegionFinish       = true
 	DefTiDBExpensiveQueryTimeThreshold = 60  // 60s
 	DefWaitSplitRegionTimeout          = 300 // 300s
+	DefTiDBAllowRemoveAutoInc          = false
 )
 
 // Process global variables.
diff --git a/sessionctx/variable/varsutil.go b/sessionctx/variable/varsutil.go
index 8196b2315aa51..bf8261f661a53 100644
--- a/sessionctx/variable/varsutil.go
+++ b/sessionctx/variable/varsutil.go
@@ -569,6 +569,14 @@ func ValidateSetSystemVar(vars *SessionVars, name string, value string) (string,
 		default:
 			return value, ErrWrongValueForVar.GenWithStackByArgs(TiDBTxnMode, value)
 		}
+	case TiDBAllowRemoveAutoInc:
+		switch {
+		case strings.EqualFold(value, "ON") || value == "1":
+			return "on", nil
+		case strings.EqualFold(value, "OFF") || value == "0":
+			return "off", nil
+		}
+		return value, ErrWrongValueForVar.GenWithStackByArgs(name, value)
 	}
 	return value, nil
 }