diff --git a/distsql/request_builder.go b/distsql/request_builder.go
index 869f255e55705..310de50149eeb 100644
--- a/distsql/request_builder.go
+++ b/distsql/request_builder.go
@@ -19,6 +19,7 @@ import (
 	"sort"
 
 	"github.com/pingcap/errors"
+	"github.com/pingcap/kvproto/pkg/metapb"
 	"github.com/pingcap/parser/mysql"
 	"github.com/pingcap/tidb/ddl/placement"
 	"github.com/pingcap/tidb/infoschema"
@@ -235,6 +236,15 @@ func (builder *RequestBuilder) SetFromSessionVars(sv *variable.SessionVars) *Req
 		builder.Request.SchemaVar = sv.TxnCtx.SchemaVersion
 	}
 	builder.txnScope = sv.TxnCtx.TxnScope
+	builder.IsStaleness = sv.TxnCtx.IsStaleness
+	if builder.IsStaleness && builder.txnScope != oracle.GlobalTxnScope {
+		builder.MatchStoreLabels = []*metapb.StoreLabel{
+			{
+				Key:   placement.DCLabelKey,
+				Value: builder.txnScope,
+			},
+		}
+	}
 	return builder
 }
 
diff --git a/executor/batch_point_get.go b/executor/batch_point_get.go
index 5ea0c2712ec8e..ca4416658306b 100644
--- a/executor/batch_point_get.go
+++ b/executor/batch_point_get.go
@@ -20,12 +20,15 @@ import (
 	"sync/atomic"
 
 	"github.com/pingcap/failpoint"
+	"github.com/pingcap/kvproto/pkg/metapb"
 	"github.com/pingcap/parser/model"
 	"github.com/pingcap/parser/mysql"
+	"github.com/pingcap/tidb/ddl/placement"
 	"github.com/pingcap/tidb/kv"
 	"github.com/pingcap/tidb/sessionctx"
 	"github.com/pingcap/tidb/sessionctx/variable"
 	"github.com/pingcap/tidb/store/tikv"
+	"github.com/pingcap/tidb/store/tikv/oracle"
 	"github.com/pingcap/tidb/tablecodec"
 	"github.com/pingcap/tidb/types"
 	"github.com/pingcap/tidb/util/chunk"
@@ -113,6 +116,16 @@ func (e *BatchPointGetExec) Open(context.Context) error {
 		snapshot.SetOption(kv.ReplicaRead, kv.ReplicaReadFollower)
 	}
 	snapshot.SetOption(kv.TaskID, e.ctx.GetSessionVars().StmtCtx.TaskID)
+	isStaleness := e.ctx.GetSessionVars().TxnCtx.IsStaleness
+	snapshot.SetOption(kv.IsStalenessReadOnly, isStaleness)
+	if isStaleness && e.ctx.GetSessionVars().TxnCtx.TxnScope != oracle.GlobalTxnScope {
+		snapshot.SetOption(kv.MatchStoreLabels, []*metapb.StoreLabel{
+			{
+				Key:   placement.DCLabelKey,
+				Value: e.ctx.GetSessionVars().TxnCtx.TxnScope,
+			},
+		})
+	}
 	var batchGetter kv.BatchGetter = snapshot
 	if txn.Valid() {
 		lock := e.tblInfo.Lock
diff --git a/executor/executor_test.go b/executor/executor_test.go
index 43d96b1a06730..b3c917323e5d8 100644
--- a/executor/executor_test.go
+++ b/executor/executor_test.go
@@ -7634,6 +7634,54 @@ func (s *testSerialSuite) TestStalenessTransaction(c *C) {
 	}
 }
 
+func (s *testSerialSuite) TestStaleReadKVRequest(c *C) {
+	c.Assert(failpoint.Enable("github.com/pingcap/tidb/executor/mockStalenessTxnSchemaVer", "return(false)"), IsNil)
+	defer failpoint.Disable("github.com/pingcap/tidb/executor/mockStalenessTxnSchemaVer")
+	tk := testkit.NewTestKit(c, s.store)
+	tk.MustExec("use test")
+	tk.MustExec("drop table if exists t")
+	tk.MustExec("create table t (id int primary key);")
+	defer tk.MustExec(`drop table if exists t`)
+	testcases := []struct {
+		name     string
+		sql      string
+		txnScope string
+		zone     string
+	}{
+		{
+			name:     "coprocessor read",
+			sql:      "select * from t",
+			txnScope: "local",
+			zone:     "sh",
+		},
+		{
+			name:     "point get read",
+			sql:      "select * from t where id = 1",
+			txnScope: "local",
+			zone:     "bj",
+		},
+		{
+			name:     "batch point get read",
+			sql:      "select * from t where id in (1,2,3)",
+			txnScope: "local",
+			zone:     "hz",
+		},
+	}
+	for _, testcase := range testcases {
+		c.Log(testcase.name)
+		tk.MustExec(fmt.Sprintf("set @@txn_scope=%v", testcase.txnScope))
+		failpoint.Enable("github.com/pingcap/tidb/config/injectTxnScope", fmt.Sprintf(`return("%v")`, testcase.zone))
+		failpoint.Enable("github.com/pingcap/tidb/store/tikv/assertStoreLabels", fmt.Sprintf(`return("%v")`, testcase.txnScope))
+		failpoint.Enable("github.com/pingcap/tidb/store/tikv/assertStaleReadFlag", `return(true)`)
+		tk.MustExec(`START TRANSACTION READ ONLY WITH TIMESTAMP BOUND EXACT STALENESS '00:00:20';`)
+		tk.MustQuery(testcase.sql)
+		tk.MustExec(`commit`)
+		failpoint.Disable("github.com/pingcap/tidb/config/injectTxnScope")
+		failpoint.Disable("github.com/pingcap/tidb/store/tikv/assertStoreLabels")
+		failpoint.Disable("github.com/pingcap/tidb/store/tikv/assertStaleReadFlag")
+	}
+}
+
 func (s *testSuite) TestStalenessAndHistoryRead(c *C) {
 	c.Assert(failpoint.Enable("github.com/pingcap/tidb/executor/mockStalenessTxnSchemaVer", "return(false)"), IsNil)
 	defer func() {
diff --git a/executor/point_get.go b/executor/point_get.go
index 91369979ed32f..0ca261b439efe 100644
--- a/executor/point_get.go
+++ b/executor/point_get.go
@@ -19,9 +19,11 @@ import (
 
 	"github.com/pingcap/errors"
 	"github.com/pingcap/failpoint"
+	"github.com/pingcap/kvproto/pkg/metapb"
 	"github.com/pingcap/parser/model"
 	"github.com/pingcap/parser/mysql"
 	"github.com/pingcap/tidb/ddl"
+	"github.com/pingcap/tidb/ddl/placement"
 	"github.com/pingcap/tidb/distsql"
 	"github.com/pingcap/tidb/expression"
 	"github.com/pingcap/tidb/infoschema"
@@ -148,6 +150,16 @@ func (e *PointGetExecutor) Open(context.Context) error {
 		e.snapshot.SetOption(kv.ReplicaRead, kv.ReplicaReadFollower)
 	}
 	e.snapshot.SetOption(kv.TaskID, e.ctx.GetSessionVars().StmtCtx.TaskID)
+	isStaleness := e.ctx.GetSessionVars().TxnCtx.IsStaleness
+	e.snapshot.SetOption(kv.IsStalenessReadOnly, isStaleness)
+	if isStaleness && e.ctx.GetSessionVars().TxnCtx.TxnScope != oracle.GlobalTxnScope {
+		e.snapshot.SetOption(kv.MatchStoreLabels, []*metapb.StoreLabel{
+			{
+				Key:   placement.DCLabelKey,
+				Value: e.ctx.GetSessionVars().TxnCtx.TxnScope,
+			},
+		})
+	}
 	return nil
 }
 
diff --git a/kv/kv.go b/kv/kv.go
index 37f5f83951cdc..bcebff808ca1f 100644
--- a/kv/kv.go
+++ b/kv/kv.go
@@ -19,6 +19,7 @@ import (
 	"sync"
 	"time"
 
+	"github.com/pingcap/kvproto/pkg/metapb"
 	"github.com/pingcap/parser/model"
 	"github.com/pingcap/tidb/config"
 	"github.com/pingcap/tidb/store/tikv/oracle"
@@ -70,6 +71,8 @@ const (
 	TxnScope
 	// StalenessReadOnly indicates whether the transaction is staleness read only transaction
 	IsStalenessReadOnly
+	// MatchStoreLabels indicates the labels the store should be matched
+	MatchStoreLabels
 )
 
 // Priority value for transaction priority.
@@ -418,6 +421,10 @@ type Request struct {
 	TaskID uint64
 	// TiDBServerID is the specified TiDB serverID to execute request. `0` means all TiDB instances.
 	TiDBServerID uint64
+	// IsStaleness indicates whether the request read staleness data
+	IsStaleness bool
+	// MatchStoreLabels indicates the labels the store should be matched
+	MatchStoreLabels []*metapb.StoreLabel
 }
 
 // ResultSubset represents a result subset from a single storage unit.
diff --git a/store/copr/coprocessor.go b/store/copr/coprocessor.go
index 4b891da6f8433..90427eed8d217 100644
--- a/store/copr/coprocessor.go
+++ b/store/copr/coprocessor.go
@@ -703,7 +703,14 @@ func (worker *copIteratorWorker) handleTaskOnce(bo *tikv.Backoffer, task *copTas
 	if worker.Stats == nil {
 		worker.Stats = make(map[tikvrpc.CmdType]*tikv.RPCRuntimeStats)
 	}
-	resp, rpcCtx, storeAddr, err := worker.SendReqCtx(bo, req, task.region, tikv.ReadTimeoutMedium, task.storeType, task.storeAddr)
+	if worker.req.IsStaleness {
+		req.EnableStaleRead()
+	}
+	var ops []tikv.StoreSelectorOption
+	if len(worker.req.MatchStoreLabels) > 0 {
+		ops = append(ops, tikv.WithMatchLabels(worker.req.MatchStoreLabels))
+	}
+	resp, rpcCtx, storeAddr, err := worker.SendReqCtx(bo, req, task.region, tikv.ReadTimeoutMedium, task.storeType, task.storeAddr, ops...)
 	if err != nil {
 		if task.storeType == kv.TiDB {
 			err = worker.handleTiDBSendReqErr(err, task, ch)
diff --git a/store/tikv/client_helper.go b/store/tikv/client_helper.go
index 8f1ee3cb1b331..aea3e7137e878 100644
--- a/store/tikv/client_helper.go
+++ b/store/tikv/client_helper.go
@@ -16,6 +16,7 @@ package tikv
 import (
 	"time"
 
+	"github.com/pingcap/failpoint"
 	"github.com/pingcap/tidb/kv"
 	"github.com/pingcap/tidb/store/tikv/tikvrpc"
 	"github.com/pingcap/tidb/store/tikv/util"
@@ -73,13 +74,20 @@ func (ch *ClientHelper) ResolveLocks(bo *Backoffer, callerStartTS uint64, locks
 }
 
 // SendReqCtx wraps the SendReqCtx function and use the resolved lock result in the kvrpcpb.Context.
-func (ch *ClientHelper) SendReqCtx(bo *Backoffer, req *tikvrpc.Request, regionID RegionVerID, timeout time.Duration, sType kv.StoreType, directStoreAddr string) (*tikvrpc.Response, *RPCContext, string, error) {
+func (ch *ClientHelper) SendReqCtx(bo *Backoffer, req *tikvrpc.Request, regionID RegionVerID, timeout time.Duration, sType kv.StoreType, directStoreAddr string, opts ...StoreSelectorOption) (*tikvrpc.Response, *RPCContext, string, error) {
 	sender := NewRegionRequestSender(ch.regionCache, ch.client)
 	if len(directStoreAddr) > 0 {
 		sender.SetStoreAddr(directStoreAddr)
 	}
 	sender.Stats = ch.Stats
 	req.Context.ResolvedLocks = ch.resolvedLocks.GetAll()
-	resp, ctx, err := sender.SendReqCtx(bo, req, regionID, timeout, sType)
+	failpoint.Inject("assertStaleReadFlag", func(val failpoint.Value) {
+		if val.(bool) {
+			if len(opts) > 0 && !req.StaleRead {
+				panic("req.StaleRead shouldn't be false when opts is not empty")
+			}
+		}
+	})
+	resp, ctx, err := sender.SendReqCtx(bo, req, regionID, timeout, sType, opts...)
 	return resp, ctx, sender.GetStoreAddr(), err
 }
diff --git a/store/tikv/region_cache.go b/store/tikv/region_cache.go
index 8ac86a9b0af2d..ba99e18d3d882 100644
--- a/store/tikv/region_cache.go
+++ b/store/tikv/region_cache.go
@@ -29,6 +29,7 @@ import (
 	"github.com/pingcap/errors"
 	"github.com/pingcap/failpoint"
 	"github.com/pingcap/kvproto/pkg/metapb"
+	"github.com/pingcap/tidb/ddl/placement"
 	"github.com/pingcap/tidb/kv"
 	"github.com/pingcap/tidb/store/tikv/config"
 	"github.com/pingcap/tidb/store/tikv/logutil"
@@ -380,6 +381,21 @@ func (c *RegionCache) GetTiKVRPCContext(bo *Backoffer, id RegionVerID, replicaRe
 	for _, op := range opts {
 		op(options)
 	}
+	failpoint.Inject("assertStoreLabels", func(val failpoint.Value) {
+		if len(opts) > 0 {
+			value := val.(string)
+			v := ""
+			for _, label := range options.labels {
+				if label.Key == placement.DCLabelKey {
+					v = label.Value
+					break
+				}
+			}
+			if v != value {
+				panic(fmt.Sprintf("StoreSelectorOption's label %v is not %v", v, value))
+			}
+		}
+	})
 	switch replicaRead {
 	case kv.ReplicaReadFollower:
 		store, peer, accessIdx, storeIdx = cachedRegion.FollowerStorePeer(regionStore, followerStoreSeed, options)
diff --git a/store/tikv/region_request.go b/store/tikv/region_request.go
index 74290ad3efbc9..a3ae52c38b82c 100644
--- a/store/tikv/region_request.go
+++ b/store/tikv/region_request.go
@@ -193,6 +193,7 @@ func (s *RegionRequestSender) getRPCContext(
 	req *tikvrpc.Request,
 	regionID RegionVerID,
 	sType kv.StoreType,
+	opts ...StoreSelectorOption,
 ) (*RPCContext, error) {
 	switch sType {
 	case kv.TiKV:
@@ -200,7 +201,7 @@ func (s *RegionRequestSender) getRPCContext(
 		if req.ReplicaReadSeed != nil {
 			seed = *req.ReplicaReadSeed
 		}
-		return s.regionCache.GetTiKVRPCContext(bo, regionID, req.ReplicaReadType, seed)
+		return s.regionCache.GetTiKVRPCContext(bo, regionID, req.ReplicaReadType, seed, opts...)
 	case kv.TiFlash:
 		return s.regionCache.GetTiFlashRPCContext(bo, regionID)
 	case kv.TiDB:
@@ -217,6 +218,7 @@ func (s *RegionRequestSender) SendReqCtx(
 	regionID RegionVerID,
 	timeout time.Duration,
 	sType kv.StoreType,
+	opts ...StoreSelectorOption,
 ) (
 	resp *tikvrpc.Response,
 	rpcCtx *RPCContext,
@@ -262,7 +264,7 @@ func (s *RegionRequestSender) SendReqCtx(
 			logutil.Logger(bo.ctx).Warn("retry get ", zap.Uint64("region = ", regionID.GetID()), zap.Int("times = ", tryTimes))
 		}
 
-		rpcCtx, err = s.getRPCContext(bo, req, regionID, sType)
+		rpcCtx, err = s.getRPCContext(bo, req, regionID, sType, opts...)
 		if err != nil {
 			return nil, nil, err
 		}
diff --git a/store/tikv/snapshot.go b/store/tikv/snapshot.go
index 21c3000a459b9..2585835d8d88c 100644
--- a/store/tikv/snapshot.go
+++ b/store/tikv/snapshot.go
@@ -29,6 +29,7 @@ import (
 	"github.com/pingcap/errors"
 	"github.com/pingcap/failpoint"
 	pb "github.com/pingcap/kvproto/pkg/kvrpcpb"
+	"github.com/pingcap/kvproto/pkg/metapb"
 	"github.com/pingcap/tidb/kv"
 	"github.com/pingcap/tidb/store/tikv/logutil"
 	"github.com/pingcap/tidb/store/tikv/metrics"
@@ -60,7 +61,10 @@ type tikvSnapshot struct {
 	keyOnly         bool
 	vars            *kv.Variables
 	replicaReadSeed uint32
-	resolvedLocks   *util.TSSet
+	isStaleness     bool
+	// MatchStoreLabels indicates the labels the store should be matched
+	matchStoreLabels []*metapb.StoreLabel
+	resolvedLocks    *util.TSSet
 
 	// Cache the result of BatchGet.
 	// The invariance is that calling BatchGet multiple times using the same start ts,
@@ -282,8 +286,14 @@ func (s *tikvSnapshot) batchGetSingleRegion(bo *Backoffer, batch batchKeys, coll
 			TaskId:       s.mu.taskID,
 		})
 		s.mu.RUnlock()
-
-		resp, _, _, err := cli.SendReqCtx(bo, req, batch.region, ReadTimeoutMedium, kv.TiKV, "")
+		var ops []StoreSelectorOption
+		if s.isStaleness {
+			req.EnableStaleRead()
+		}
+		if len(s.matchStoreLabels) > 0 {
+			ops = append(ops, WithMatchLabels(s.matchStoreLabels))
+		}
+		resp, _, _, err := cli.SendReqCtx(bo, req, batch.region, ReadTimeoutMedium, kv.TiKV, "", ops...)
 
 		if err != nil {
 			return errors.Trace(err)
@@ -430,13 +440,19 @@ func (s *tikvSnapshot) get(ctx context.Context, bo *Backoffer, k kv.Key) ([]byte
 			TaskId:       s.mu.taskID,
 		})
 	s.mu.RUnlock()
-
+	var ops []StoreSelectorOption
+	if s.isStaleness {
+		req.EnableStaleRead()
+	}
+	if len(s.matchStoreLabels) > 0 {
+		ops = append(ops, WithMatchLabels(s.matchStoreLabels))
+	}
 	for {
 		loc, err := s.store.regionCache.LocateKey(bo, k)
 		if err != nil {
 			return nil, errors.Trace(err)
 		}
-		resp, _, _, err := cli.SendReqCtx(bo, req, loc.Region, readTimeoutShort, kv.TiKV, "")
+		resp, _, _, err := cli.SendReqCtx(bo, req, loc.Region, readTimeoutShort, kv.TiKV, "", ops...)
 		if err != nil {
 			return nil, errors.Trace(err)
 		}
@@ -552,6 +568,12 @@ func (s *tikvSnapshot) SetOption(opt kv.Option, val interface{}) {
 		s.mu.Unlock()
 	case kv.SampleStep:
 		s.sampleStep = val.(uint32)
+	case kv.IsStalenessReadOnly:
+		s.mu.Lock()
+		s.isStaleness = val.(bool)
+		s.mu.Unlock()
+	case kv.MatchStoreLabels:
+		s.matchStoreLabels = val.([]*metapb.StoreLabel)
 	case kv.TxnScope:
 		s.txnScope = val.(string)
 	}
diff --git a/store/tikv/tikvrpc/tikvrpc.go b/store/tikv/tikvrpc/tikvrpc.go
index 3d19d7d64bb44..c695f8ecb3827 100644
--- a/store/tikv/tikvrpc/tikvrpc.go
+++ b/store/tikv/tikvrpc/tikvrpc.go
@@ -389,6 +389,13 @@ func (req *Request) TxnHeartBeat() *kvrpcpb.TxnHeartBeatRequest {
 	return req.Req.(*kvrpcpb.TxnHeartBeatRequest)
 }
 
+// EnableStaleRead enables stale read
+func (req *Request) EnableStaleRead() {
+	req.StaleRead = true
+	req.ReplicaReadType = kv.ReplicaReadMixed
+	req.ReplicaRead = false
+}
+
 // ToBatchCommandsRequest converts the request to an entry in BatchCommands request.
 func (req *Request) ToBatchCommandsRequest() *tikvpb.BatchCommandsRequest_Request {
 	switch req.Type {