diff --git a/executor/adapter.go b/executor/adapter.go
index aaa1c5cfc4f6b..b2e7c2c78f643 100644
--- a/executor/adapter.go
+++ b/executor/adapter.go
@@ -841,7 +841,7 @@ type pessimisticTxn interface {
 	KeysNeedToLock() ([]kv.Key, error)
 }
 
-// buildExecutor build a executor from plan, prepared statement may need additional procedure.
+// buildExecutor build an executor from plan, prepared statement may need additional procedure.
 func (a *ExecStmt) buildExecutor() (Executor, error) {
 	ctx := a.Ctx
 	stmtCtx := ctx.GetSessionVars().StmtCtx
diff --git a/planner/core/logical_plan_builder.go b/planner/core/logical_plan_builder.go
index 69773f62d9535..a7083de475ba9 100644
--- a/planner/core/logical_plan_builder.go
+++ b/planner/core/logical_plan_builder.go
@@ -4488,7 +4488,9 @@ func (ds *DataSource) ExtractFD() *fd.FDSet {
 			changed       bool
 			err           error
 		)
-		if ds.isForUpdateRead {
+		check := ds.ctx.GetSessionVars().IsIsolation(ast.ReadCommitted) || ds.isForUpdateRead
+		check = check && ds.ctx.GetSessionVars().ConnectionID > 0
+		if check {
 			latestIndexes, changed, err = getLatestIndexInfo(ds.ctx, ds.table.Meta().ID, 0)
 			if err != nil {
 				ds.fdSet = fds
diff --git a/planner/core/planbuilder.go b/planner/core/planbuilder.go
index f2005a20c40be..e41731103b91e 100644
--- a/planner/core/planbuilder.go
+++ b/planner/core/planbuilder.go
@@ -1095,6 +1095,7 @@ func getPossibleAccessPaths(ctx sessionctx.Context, tableHints *tableHintInfo, i
 
 	optimizerUseInvisibleIndexes := ctx.GetSessionVars().OptimizerUseInvisibleIndexes
 
+	check = check || ctx.GetSessionVars().IsIsolation(ast.ReadCommitted)
 	check = check && ctx.GetSessionVars().ConnectionID > 0
 	var latestIndexes map[int64]*model.IndexInfo
 	var err error
@@ -1594,7 +1595,8 @@ func (b *PlanBuilder) buildPhysicalIndexLookUpReaders(ctx context.Context, dbNam
 	indexInfos := make([]*model.IndexInfo, 0, len(tblInfo.Indices))
 	indexLookUpReaders := make([]Plan, 0, len(tblInfo.Indices))
 
-	check := b.isForUpdateRead && b.ctx.GetSessionVars().ConnectionID > 0
+	check := b.isForUpdateRead || b.ctx.GetSessionVars().IsIsolation(ast.ReadCommitted)
+	check = check && b.ctx.GetSessionVars().ConnectionID > 0
 	var latestIndexes map[int64]*model.IndexInfo
 	var err error
 
diff --git a/planner/core/point_get_plan.go b/planner/core/point_get_plan.go
index 794cc01490a3e..afb34814f7196 100644
--- a/planner/core/point_get_plan.go
+++ b/planner/core/point_get_plan.go
@@ -945,6 +945,7 @@ func tryPointGetPlan(ctx sessionctx.Context, selStmt *ast.SelectStmt, check bool
 		return nil
 	}
 
+	check = check || ctx.GetSessionVars().IsIsolation(ast.ReadCommitted)
 	check = check && ctx.GetSessionVars().ConnectionID > 0
 	var latestIndexes map[int64]*model.IndexInfo
 	var err error
diff --git a/planner/core/prepare_test.go b/planner/core/prepare_test.go
index f20b9673a33ca..a02e955a93eba 100644
--- a/planner/core/prepare_test.go
+++ b/planner/core/prepare_test.go
@@ -2805,3 +2805,50 @@ func TestCachedTable(t *testing.T) {
 	require.True(t, lastReadFromCache(tk))
 	tk.MustQuery("select @@last_plan_from_cache").Check(testkit.Rows("1"))
 }
+
+func TestPlanCacheWithRCWhenInfoSchemaChange(t *testing.T) {
+	orgEnable := core.PreparedPlanCacheEnabled()
+	defer func() {
+		core.SetPreparedPlanCache(orgEnable)
+	}()
+	core.SetPreparedPlanCache(true)
+
+	ctx := context.Background()
+	store, clean := testkit.CreateMockStore(t)
+	defer clean()
+
+	tk1 := testkit.NewTestKit(t, store)
+	tk2 := testkit.NewTestKit(t, store)
+	tk1.MustExec("use test")
+	tk2.MustExec("use test")
+	tk1.MustExec("drop table if exists t1")
+	tk1.MustExec("create table t1(id int primary key, c int, index ic (c))")
+	// prepare text protocol
+	tk1.MustExec("prepare s from 'select /*+use_index(t1, ic)*/ * from t1 where 1'")
+	// prepare binary protocol
+	stmtID, _, _, err := tk2.Session().PrepareStmt("select /*+use_index(t1, ic)*/ * from t1 where 1")
+	require.Nil(t, err)
+	tk1.MustExec("set tx_isolation='READ-COMMITTED'")
+	tk1.MustExec("begin pessimistic")
+	tk2.MustExec("set tx_isolation='READ-COMMITTED'")
+	tk2.MustExec("begin pessimistic")
+	tk1.MustQuery("execute s").Check(testkit.Rows())
+	rs, err := tk2.Session().ExecutePreparedStmt(ctx, stmtID, []types.Datum{})
+	require.Nil(t, err)
+	tk2.ResultSetToResult(rs, fmt.Sprintf("%v", rs)).Check(testkit.Rows())
+
+	tk3 := testkit.NewTestKit(t, store)
+	tk3.MustExec("use test")
+	tk3.MustExec("alter table t1 drop index ic")
+	tk3.MustExec("insert into t1 values(1, 0)")
+
+	// The execution after schema changed should not hit plan cache.
+	// execute text protocol
+	tk1.MustQuery("execute s").Check(testkit.Rows("1 0"))
+	tk1.MustQuery("select @@last_plan_from_cache").Check(testkit.Rows("0"))
+	// execute binary protocol
+	rs, err = tk2.Session().ExecutePreparedStmt(ctx, stmtID, []types.Datum{})
+	require.Nil(t, err)
+	tk2.ResultSetToResult(rs, fmt.Sprintf("%v", rs)).Check(testkit.Rows("1 0"))
+	tk2.MustQuery("select @@last_plan_from_cache").Check(testkit.Rows("0"))
+}
diff --git a/planner/core/rule_build_key_info.go b/planner/core/rule_build_key_info.go
index a1e7798ac0dfa..22ec84d150bc4 100644
--- a/planner/core/rule_build_key_info.go
+++ b/planner/core/rule_build_key_info.go
@@ -267,8 +267,10 @@ func (ds *DataSource) BuildKeyInfo(selfSchema *expression.Schema, childSchema []
 	var latestIndexes map[int64]*model.IndexInfo
 	var changed bool
 	var err error
+	check := ds.ctx.GetSessionVars().IsIsolation(ast.ReadCommitted) || ds.isForUpdateRead
+	check = check && ds.ctx.GetSessionVars().ConnectionID > 0
 	// we should check index valid while forUpdateRead, see detail in https://github.com/pingcap/tidb/pull/22152
-	if ds.isForUpdateRead {
+	if check {
 		latestIndexes, changed, err = getLatestIndexInfo(ds.ctx, ds.table.Meta().ID, 0)
 		if err != nil {
 			return
diff --git a/planner/optimize.go b/planner/optimize.go
index 26328f64b610a..112932b6c595b 100644
--- a/planner/optimize.go
+++ b/planner/optimize.go
@@ -73,7 +73,12 @@ func GetExecuteForUpdateReadIS(node ast.Node, sctx sessionctx.Context) infoschem
 			execID = vars.PreparedStmtNameToID[execStmt.Name]
 		}
 		if preparedPointer, ok := vars.PreparedStmts[execID]; ok {
-			if preparedObj, ok := preparedPointer.(*core.CachedPrepareStmt); ok && preparedObj.ForUpdateRead {
+			checkSchema := vars.IsIsolation(ast.ReadCommitted)
+			if !checkSchema {
+				preparedObj, ok := preparedPointer.(*core.CachedPrepareStmt)
+				checkSchema = ok && preparedObj.ForUpdateRead
+			}
+			if checkSchema {
 				is := domain.GetDomain(sctx).InfoSchema()
 				return temptable.AttachLocalTemporaryTableInfoSchema(sctx, is)
 			}
diff --git a/session/session.go b/session/session.go
index 6f79bfb968609..eecc0be9000dc 100644
--- a/session/session.go
+++ b/session/session.go
@@ -2373,8 +2373,9 @@ func (s *session) ExecutePreparedStmt(ctx context.Context, stmtID uint32, args [
 		if err != nil {
 			return nil, err
 		}
-	} else if preparedStmt.ForUpdateRead {
+	} else if s.sessionVars.IsIsolation(ast.ReadCommitted) || preparedStmt.ForUpdateRead {
 		is = domain.GetDomain(s).InfoSchema()
+		is = temptable.AttachLocalTemporaryTableInfoSchema(s, is)
 	} else {
 		is = s.GetInfoSchema().(infoschema.InfoSchema)
 	}