ImersãoDados_aula04.ipynb

{
  "nbformat": 4,
  "nbformat_minor": 0,
  "metadata": {
    "colab": {
      "name": "Desafios_aula04.ipynb",
      "provenance": [],
      "collapsed_sections": [
        "S75is34q0v4P",
        "QseZWtW-1c0o",
        "vhAZrLOS4rLA",
        "o57IvKLm5CXg",
        "kF8JJNjN5fSp",
        "KKAFUzM75qU_",
        "ItLntkJk6XXg"
      ]
    },
    "kernelspec": {
      "name": "python3",
      "display_name": "Python 3"
    },
    "language_info": {
      "name": "python"
    }
  },
  "cells": [
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "S75is34q0v4P"
      },
      "source": [
        "## **Anotações: Aula 04**"
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 435
        },
        "id": "IB56AJDvzG4y",
        "outputId": "8496bc5f-b534-4b93-ef66-78f36822e02f"
      },
      "source": [
        "import pandas as pd\n",
        "import numpy as np\n",
        "import seaborn as sns\n",
        "import matplotlib.pyplot as plt\n",
        "sns.set()\n",
        "\n",
        "url_dados = 'https://github.com/alura-cursos/imersaodados3/blob/main/dados/dados_experimentos.zip?raw=true'\n",
        "\n",
        "dados = pd.read_csv(url_dados, compression = 'zip')\n",
        "dados"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>tratamento</th>\n",
              "      <th>tempo</th>\n",
              "      <th>dose</th>\n",
              "      <th>droga</th>\n",
              "      <th>g-0</th>\n",
              "      <th>g-1</th>\n",
              "      <th>g-2</th>\n",
              "      <th>g-3</th>\n",
              "      <th>g-4</th>\n",
              "      <th>g-5</th>\n",
              "      <th>g-6</th>\n",
              "      <th>g-7</th>\n",
              "      <th>g-8</th>\n",
              "      <th>g-9</th>\n",
              "      <th>g-10</th>\n",
              "      <th>g-11</th>\n",
              "      <th>g-12</th>\n",
              "      <th>g-13</th>\n",
              "      <th>g-14</th>\n",
              "      <th>g-15</th>\n",
              "      <th>g-16</th>\n",
              "      <th>g-17</th>\n",
              "      <th>g-18</th>\n",
              "      <th>g-19</th>\n",
              "      <th>g-20</th>\n",
              "      <th>g-21</th>\n",
              "      <th>g-22</th>\n",
              "      <th>g-23</th>\n",
              "      <th>g-24</th>\n",
              "      <th>g-25</th>\n",
              "      <th>g-26</th>\n",
              "      <th>g-27</th>\n",
              "      <th>g-28</th>\n",
              "      <th>g-29</th>\n",
              "      <th>g-30</th>\n",
              "      <th>g-31</th>\n",
              "      <th>g-32</th>\n",
              "      <th>g-33</th>\n",
              "      <th>g-34</th>\n",
              "      <th>...</th>\n",
              "      <th>c-60</th>\n",
              "      <th>c-61</th>\n",
              "      <th>c-62</th>\n",
              "      <th>c-63</th>\n",
              "      <th>c-64</th>\n",
              "      <th>c-65</th>\n",
              "      <th>c-66</th>\n",
              "      <th>c-67</th>\n",
              "      <th>c-68</th>\n",
              "      <th>c-69</th>\n",
              "      <th>c-70</th>\n",
              "      <th>c-71</th>\n",
              "      <th>c-72</th>\n",
              "      <th>c-73</th>\n",
              "      <th>c-74</th>\n",
              "      <th>c-75</th>\n",
              "      <th>c-76</th>\n",
              "      <th>c-77</th>\n",
              "      <th>c-78</th>\n",
              "      <th>c-79</th>\n",
              "      <th>c-80</th>\n",
              "      <th>c-81</th>\n",
              "      <th>c-82</th>\n",
              "      <th>c-83</th>\n",
              "      <th>c-84</th>\n",
              "      <th>c-85</th>\n",
              "      <th>c-86</th>\n",
              "      <th>c-87</th>\n",
              "      <th>c-88</th>\n",
              "      <th>c-89</th>\n",
              "      <th>c-90</th>\n",
              "      <th>c-91</th>\n",
              "      <th>c-92</th>\n",
              "      <th>c-93</th>\n",
              "      <th>c-94</th>\n",
              "      <th>c-95</th>\n",
              "      <th>c-96</th>\n",
              "      <th>c-97</th>\n",
              "      <th>c-98</th>\n",
              "      <th>c-99</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D1</td>\n",
              "      <td>b68db1d53</td>\n",
              "      <td>1.0620</td>\n",
              "      <td>0.5577</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-0.6208</td>\n",
              "      <td>-0.1944</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>-1.0220</td>\n",
              "      <td>-0.0326</td>\n",
              "      <td>0.5548</td>\n",
              "      <td>-0.0921</td>\n",
              "      <td>1.1830</td>\n",
              "      <td>0.1530</td>\n",
              "      <td>0.5574</td>\n",
              "      <td>-0.4015</td>\n",
              "      <td>0.1789</td>\n",
              "      <td>-0.6528</td>\n",
              "      <td>-0.7969</td>\n",
              "      <td>0.6342</td>\n",
              "      <td>0.1778</td>\n",
              "      <td>-0.3694</td>\n",
              "      <td>-0.5688</td>\n",
              "      <td>-1.1360</td>\n",
              "      <td>-1.1880</td>\n",
              "      <td>0.6940</td>\n",
              "      <td>0.4393</td>\n",
              "      <td>0.2664</td>\n",
              "      <td>0.1907</td>\n",
              "      <td>0.1628</td>\n",
              "      <td>-0.2853</td>\n",
              "      <td>0.5819</td>\n",
              "      <td>0.2934</td>\n",
              "      <td>-0.5584</td>\n",
              "      <td>-0.0916</td>\n",
              "      <td>-0.3010</td>\n",
              "      <td>-0.1537</td>\n",
              "      <td>...</td>\n",
              "      <td>0.4805</td>\n",
              "      <td>0.4965</td>\n",
              "      <td>0.3680</td>\n",
              "      <td>0.8427</td>\n",
              "      <td>0.1042</td>\n",
              "      <td>0.1403</td>\n",
              "      <td>0.1758</td>\n",
              "      <td>1.2570</td>\n",
              "      <td>-0.5979</td>\n",
              "      <td>1.2250</td>\n",
              "      <td>-0.0553</td>\n",
              "      <td>0.7351</td>\n",
              "      <td>0.5810</td>\n",
              "      <td>0.9590</td>\n",
              "      <td>0.2427</td>\n",
              "      <td>0.0495</td>\n",
              "      <td>0.4141</td>\n",
              "      <td>0.8432</td>\n",
              "      <td>0.6162</td>\n",
              "      <td>-0.7318</td>\n",
              "      <td>1.2120</td>\n",
              "      <td>0.6362</td>\n",
              "      <td>-0.4427</td>\n",
              "      <td>0.1288</td>\n",
              "      <td>1.4840</td>\n",
              "      <td>0.1799</td>\n",
              "      <td>0.5367</td>\n",
              "      <td>-0.1111</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>0.6685</td>\n",
              "      <td>0.2862</td>\n",
              "      <td>0.2584</td>\n",
              "      <td>0.8076</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.1912</td>\n",
              "      <td>0.6584</td>\n",
              "      <td>-0.3981</td>\n",
              "      <td>0.2139</td>\n",
              "      <td>0.3801</td>\n",
              "      <td>0.4176</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D1</td>\n",
              "      <td>df89a8e5a</td>\n",
              "      <td>0.0743</td>\n",
              "      <td>0.4087</td>\n",
              "      <td>0.2991</td>\n",
              "      <td>0.0604</td>\n",
              "      <td>1.0190</td>\n",
              "      <td>0.5207</td>\n",
              "      <td>0.2341</td>\n",
              "      <td>0.3372</td>\n",
              "      <td>-0.4047</td>\n",
              "      <td>0.8507</td>\n",
              "      <td>-1.1520</td>\n",
              "      <td>-0.4201</td>\n",
              "      <td>-0.0958</td>\n",
              "      <td>0.4590</td>\n",
              "      <td>0.0803</td>\n",
              "      <td>0.2250</td>\n",
              "      <td>0.5293</td>\n",
              "      <td>0.2839</td>\n",
              "      <td>-0.3494</td>\n",
              "      <td>0.2883</td>\n",
              "      <td>0.9449</td>\n",
              "      <td>-0.1646</td>\n",
              "      <td>-0.2657</td>\n",
              "      <td>-0.3372</td>\n",
              "      <td>0.3135</td>\n",
              "      <td>-0.4316</td>\n",
              "      <td>0.4773</td>\n",
              "      <td>0.2075</td>\n",
              "      <td>-0.4216</td>\n",
              "      <td>-0.1161</td>\n",
              "      <td>-0.0499</td>\n",
              "      <td>-0.2627</td>\n",
              "      <td>0.9959</td>\n",
              "      <td>-0.2483</td>\n",
              "      <td>0.2655</td>\n",
              "      <td>...</td>\n",
              "      <td>0.4083</td>\n",
              "      <td>0.0319</td>\n",
              "      <td>0.3905</td>\n",
              "      <td>0.7099</td>\n",
              "      <td>0.2912</td>\n",
              "      <td>0.4151</td>\n",
              "      <td>-0.2840</td>\n",
              "      <td>-0.3104</td>\n",
              "      <td>-0.6373</td>\n",
              "      <td>0.2887</td>\n",
              "      <td>-0.0765</td>\n",
              "      <td>0.2539</td>\n",
              "      <td>0.4443</td>\n",
              "      <td>0.5932</td>\n",
              "      <td>0.2031</td>\n",
              "      <td>0.7639</td>\n",
              "      <td>0.5499</td>\n",
              "      <td>-0.3322</td>\n",
              "      <td>-0.0977</td>\n",
              "      <td>0.4329</td>\n",
              "      <td>-0.2782</td>\n",
              "      <td>0.7827</td>\n",
              "      <td>0.5934</td>\n",
              "      <td>0.3402</td>\n",
              "      <td>0.1499</td>\n",
              "      <td>0.4420</td>\n",
              "      <td>0.9366</td>\n",
              "      <td>0.8193</td>\n",
              "      <td>-0.4236</td>\n",
              "      <td>0.3192</td>\n",
              "      <td>-0.4265</td>\n",
              "      <td>0.7543</td>\n",
              "      <td>0.4708</td>\n",
              "      <td>0.0230</td>\n",
              "      <td>0.2957</td>\n",
              "      <td>0.4899</td>\n",
              "      <td>0.1522</td>\n",
              "      <td>0.1241</td>\n",
              "      <td>0.6077</td>\n",
              "      <td>0.7371</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>48</td>\n",
              "      <td>D1</td>\n",
              "      <td>18bb41b2c</td>\n",
              "      <td>0.6280</td>\n",
              "      <td>0.5817</td>\n",
              "      <td>1.5540</td>\n",
              "      <td>-0.0764</td>\n",
              "      <td>-0.0323</td>\n",
              "      <td>1.2390</td>\n",
              "      <td>0.1715</td>\n",
              "      <td>0.2155</td>\n",
              "      <td>0.0065</td>\n",
              "      <td>1.2300</td>\n",
              "      <td>-0.4797</td>\n",
              "      <td>-0.5631</td>\n",
              "      <td>-0.0366</td>\n",
              "      <td>-1.8300</td>\n",
              "      <td>0.6057</td>\n",
              "      <td>-0.3278</td>\n",
              "      <td>0.6042</td>\n",
              "      <td>-0.3075</td>\n",
              "      <td>-0.1147</td>\n",
              "      <td>-0.0570</td>\n",
              "      <td>-0.0799</td>\n",
              "      <td>-0.8181</td>\n",
              "      <td>-1.5320</td>\n",
              "      <td>0.2307</td>\n",
              "      <td>0.4901</td>\n",
              "      <td>0.4780</td>\n",
              "      <td>-1.3970</td>\n",
              "      <td>4.6240</td>\n",
              "      <td>-0.0437</td>\n",
              "      <td>1.2870</td>\n",
              "      <td>-1.8530</td>\n",
              "      <td>0.6069</td>\n",
              "      <td>0.4290</td>\n",
              "      <td>0.1783</td>\n",
              "      <td>0.0018</td>\n",
              "      <td>...</td>\n",
              "      <td>-0.5477</td>\n",
              "      <td>-0.7576</td>\n",
              "      <td>-0.0444</td>\n",
              "      <td>0.1894</td>\n",
              "      <td>-0.0014</td>\n",
              "      <td>-2.3640</td>\n",
              "      <td>-0.4682</td>\n",
              "      <td>0.1210</td>\n",
              "      <td>-0.5177</td>\n",
              "      <td>-0.0604</td>\n",
              "      <td>0.1682</td>\n",
              "      <td>-0.4436</td>\n",
              "      <td>0.4963</td>\n",
              "      <td>0.1363</td>\n",
              "      <td>0.3335</td>\n",
              "      <td>0.9760</td>\n",
              "      <td>-0.0427</td>\n",
              "      <td>-0.1235</td>\n",
              "      <td>0.0959</td>\n",
              "      <td>0.0690</td>\n",
              "      <td>-0.9416</td>\n",
              "      <td>-0.7548</td>\n",
              "      <td>-0.1109</td>\n",
              "      <td>-0.6272</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>0.1172</td>\n",
              "      <td>0.1093</td>\n",
              "      <td>-0.3113</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>-0.0873</td>\n",
              "      <td>-0.7250</td>\n",
              "      <td>-0.6297</td>\n",
              "      <td>0.6103</td>\n",
              "      <td>0.0223</td>\n",
              "      <td>-1.3240</td>\n",
              "      <td>-0.3174</td>\n",
              "      <td>-0.6417</td>\n",
              "      <td>-0.2187</td>\n",
              "      <td>-1.4080</td>\n",
              "      <td>0.6931</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>48</td>\n",
              "      <td>D1</td>\n",
              "      <td>8c7f86626</td>\n",
              "      <td>-0.5138</td>\n",
              "      <td>-0.2491</td>\n",
              "      <td>-0.2656</td>\n",
              "      <td>0.5288</td>\n",
              "      <td>4.0620</td>\n",
              "      <td>-0.8095</td>\n",
              "      <td>-1.9590</td>\n",
              "      <td>0.1792</td>\n",
              "      <td>-0.1321</td>\n",
              "      <td>-1.0600</td>\n",
              "      <td>-0.8269</td>\n",
              "      <td>-0.3584</td>\n",
              "      <td>-0.8511</td>\n",
              "      <td>-0.5844</td>\n",
              "      <td>-2.5690</td>\n",
              "      <td>0.8183</td>\n",
              "      <td>-0.0532</td>\n",
              "      <td>-0.8554</td>\n",
              "      <td>0.1160</td>\n",
              "      <td>-2.3520</td>\n",
              "      <td>2.1200</td>\n",
              "      <td>-1.1580</td>\n",
              "      <td>-0.7191</td>\n",
              "      <td>-0.8004</td>\n",
              "      <td>-1.4670</td>\n",
              "      <td>-0.0107</td>\n",
              "      <td>-0.8995</td>\n",
              "      <td>0.2406</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-1.0890</td>\n",
              "      <td>-0.7575</td>\n",
              "      <td>0.0881</td>\n",
              "      <td>-2.7370</td>\n",
              "      <td>0.8745</td>\n",
              "      <td>0.5787</td>\n",
              "      <td>...</td>\n",
              "      <td>-2.1220</td>\n",
              "      <td>-0.3752</td>\n",
              "      <td>-2.3820</td>\n",
              "      <td>-3.7350</td>\n",
              "      <td>-2.9740</td>\n",
              "      <td>-1.4930</td>\n",
              "      <td>-1.6600</td>\n",
              "      <td>-3.1660</td>\n",
              "      <td>0.2816</td>\n",
              "      <td>-0.2990</td>\n",
              "      <td>-1.1870</td>\n",
              "      <td>-0.5044</td>\n",
              "      <td>-1.7750</td>\n",
              "      <td>-1.6120</td>\n",
              "      <td>-0.9215</td>\n",
              "      <td>-1.0810</td>\n",
              "      <td>-3.0520</td>\n",
              "      <td>-3.4470</td>\n",
              "      <td>-2.7740</td>\n",
              "      <td>-1.8460</td>\n",
              "      <td>-0.5568</td>\n",
              "      <td>-3.3960</td>\n",
              "      <td>-2.9510</td>\n",
              "      <td>-1.1550</td>\n",
              "      <td>-3.2620</td>\n",
              "      <td>-1.5390</td>\n",
              "      <td>-2.4600</td>\n",
              "      <td>-0.9417</td>\n",
              "      <td>-1.5550</td>\n",
              "      <td>0.2431</td>\n",
              "      <td>-2.0990</td>\n",
              "      <td>-0.6441</td>\n",
              "      <td>-5.6300</td>\n",
              "      <td>-1.3780</td>\n",
              "      <td>-0.8632</td>\n",
              "      <td>-1.2880</td>\n",
              "      <td>-1.6210</td>\n",
              "      <td>-0.8784</td>\n",
              "      <td>-0.3876</td>\n",
              "      <td>-0.8154</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D2</td>\n",
              "      <td>7cbed3131</td>\n",
              "      <td>-0.3254</td>\n",
              "      <td>-0.4009</td>\n",
              "      <td>0.9700</td>\n",
              "      <td>0.6919</td>\n",
              "      <td>1.4180</td>\n",
              "      <td>-0.8244</td>\n",
              "      <td>-0.2800</td>\n",
              "      <td>-0.1498</td>\n",
              "      <td>-0.8789</td>\n",
              "      <td>0.8630</td>\n",
              "      <td>-0.2219</td>\n",
              "      <td>-0.5121</td>\n",
              "      <td>-0.9577</td>\n",
              "      <td>1.1750</td>\n",
              "      <td>0.2042</td>\n",
              "      <td>0.1970</td>\n",
              "      <td>0.1244</td>\n",
              "      <td>-1.7090</td>\n",
              "      <td>-0.3543</td>\n",
              "      <td>-0.5160</td>\n",
              "      <td>-0.3330</td>\n",
              "      <td>-0.2685</td>\n",
              "      <td>0.7649</td>\n",
              "      <td>0.2057</td>\n",
              "      <td>1.3720</td>\n",
              "      <td>0.6835</td>\n",
              "      <td>0.8056</td>\n",
              "      <td>-0.3754</td>\n",
              "      <td>-1.2090</td>\n",
              "      <td>0.2965</td>\n",
              "      <td>-0.0712</td>\n",
              "      <td>0.6389</td>\n",
              "      <td>0.6674</td>\n",
              "      <td>-0.0783</td>\n",
              "      <td>1.1740</td>\n",
              "      <td>...</td>\n",
              "      <td>-0.2274</td>\n",
              "      <td>0.3215</td>\n",
              "      <td>0.1535</td>\n",
              "      <td>-0.4640</td>\n",
              "      <td>-0.5943</td>\n",
              "      <td>0.3973</td>\n",
              "      <td>0.1500</td>\n",
              "      <td>0.5178</td>\n",
              "      <td>0.5159</td>\n",
              "      <td>0.6091</td>\n",
              "      <td>0.1813</td>\n",
              "      <td>-0.4249</td>\n",
              "      <td>0.7832</td>\n",
              "      <td>0.6529</td>\n",
              "      <td>0.5648</td>\n",
              "      <td>0.4817</td>\n",
              "      <td>0.0587</td>\n",
              "      <td>0.5303</td>\n",
              "      <td>0.6376</td>\n",
              "      <td>-0.3966</td>\n",
              "      <td>-1.4950</td>\n",
              "      <td>-0.9625</td>\n",
              "      <td>-0.0541</td>\n",
              "      <td>0.6273</td>\n",
              "      <td>0.4563</td>\n",
              "      <td>0.0698</td>\n",
              "      <td>0.8134</td>\n",
              "      <td>0.1924</td>\n",
              "      <td>0.6054</td>\n",
              "      <td>-0.1824</td>\n",
              "      <td>0.0042</td>\n",
              "      <td>0.0048</td>\n",
              "      <td>0.6670</td>\n",
              "      <td>1.0690</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.3031</td>\n",
              "      <td>0.1094</td>\n",
              "      <td>0.2885</td>\n",
              "      <td>-0.3786</td>\n",
              "      <td>0.7125</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>...</th>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23809</th>\n",
              "      <td>id_fffb1ceed</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D2</td>\n",
              "      <td>df1d0a5a1</td>\n",
              "      <td>0.1394</td>\n",
              "      <td>-0.0636</td>\n",
              "      <td>-0.1112</td>\n",
              "      <td>-0.5080</td>\n",
              "      <td>-0.4713</td>\n",
              "      <td>0.7201</td>\n",
              "      <td>0.5773</td>\n",
              "      <td>0.3055</td>\n",
              "      <td>-0.4726</td>\n",
              "      <td>0.1269</td>\n",
              "      <td>0.2531</td>\n",
              "      <td>0.1730</td>\n",
              "      <td>-0.4532</td>\n",
              "      <td>-1.0790</td>\n",
              "      <td>0.2474</td>\n",
              "      <td>-0.4550</td>\n",
              "      <td>0.3588</td>\n",
              "      <td>0.1600</td>\n",
              "      <td>-0.7362</td>\n",
              "      <td>-0.1103</td>\n",
              "      <td>0.8550</td>\n",
              "      <td>-0.4139</td>\n",
              "      <td>0.5541</td>\n",
              "      <td>0.2310</td>\n",
              "      <td>-0.5573</td>\n",
              "      <td>-0.4397</td>\n",
              "      <td>-0.9260</td>\n",
              "      <td>-0.2424</td>\n",
              "      <td>-0.6686</td>\n",
              "      <td>0.2326</td>\n",
              "      <td>0.6456</td>\n",
              "      <td>0.0136</td>\n",
              "      <td>-0.5141</td>\n",
              "      <td>-0.6320</td>\n",
              "      <td>0.7166</td>\n",
              "      <td>...</td>\n",
              "      <td>0.0807</td>\n",
              "      <td>0.4024</td>\n",
              "      <td>-0.0895</td>\n",
              "      <td>0.4420</td>\n",
              "      <td>0.9641</td>\n",
              "      <td>-0.1846</td>\n",
              "      <td>-0.0014</td>\n",
              "      <td>0.3154</td>\n",
              "      <td>-0.2071</td>\n",
              "      <td>-0.6158</td>\n",
              "      <td>-0.2977</td>\n",
              "      <td>0.0992</td>\n",
              "      <td>0.6838</td>\n",
              "      <td>0.5259</td>\n",
              "      <td>0.7882</td>\n",
              "      <td>0.3119</td>\n",
              "      <td>-0.7697</td>\n",
              "      <td>0.2203</td>\n",
              "      <td>-1.0710</td>\n",
              "      <td>0.5979</td>\n",
              "      <td>0.0848</td>\n",
              "      <td>-0.2555</td>\n",
              "      <td>0.6293</td>\n",
              "      <td>1.1660</td>\n",
              "      <td>0.3329</td>\n",
              "      <td>0.2754</td>\n",
              "      <td>0.4108</td>\n",
              "      <td>-0.1252</td>\n",
              "      <td>-0.2340</td>\n",
              "      <td>0.2267</td>\n",
              "      <td>0.1969</td>\n",
              "      <td>0.0262</td>\n",
              "      <td>-0.8121</td>\n",
              "      <td>0.3434</td>\n",
              "      <td>0.5372</td>\n",
              "      <td>-0.3246</td>\n",
              "      <td>0.0631</td>\n",
              "      <td>0.9171</td>\n",
              "      <td>0.5258</td>\n",
              "      <td>0.4680</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23810</th>\n",
              "      <td>id_fffb70c0c</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D2</td>\n",
              "      <td>ecf3b6b74</td>\n",
              "      <td>-1.3260</td>\n",
              "      <td>0.3478</td>\n",
              "      <td>-0.3743</td>\n",
              "      <td>0.9905</td>\n",
              "      <td>-0.7178</td>\n",
              "      <td>0.6621</td>\n",
              "      <td>-0.2252</td>\n",
              "      <td>-0.5565</td>\n",
              "      <td>0.5112</td>\n",
              "      <td>0.6727</td>\n",
              "      <td>-0.1851</td>\n",
              "      <td>2.8650</td>\n",
              "      <td>-0.2140</td>\n",
              "      <td>-0.6153</td>\n",
              "      <td>0.8362</td>\n",
              "      <td>0.5584</td>\n",
              "      <td>-0.2589</td>\n",
              "      <td>0.1292</td>\n",
              "      <td>0.0148</td>\n",
              "      <td>0.0949</td>\n",
              "      <td>-0.2182</td>\n",
              "      <td>-0.9235</td>\n",
              "      <td>0.0749</td>\n",
              "      <td>-1.5910</td>\n",
              "      <td>-0.8359</td>\n",
              "      <td>-0.9217</td>\n",
              "      <td>0.3013</td>\n",
              "      <td>0.1716</td>\n",
              "      <td>0.0880</td>\n",
              "      <td>0.1842</td>\n",
              "      <td>0.1835</td>\n",
              "      <td>0.5436</td>\n",
              "      <td>-0.0533</td>\n",
              "      <td>-0.0491</td>\n",
              "      <td>0.9543</td>\n",
              "      <td>...</td>\n",
              "      <td>0.1410</td>\n",
              "      <td>1.2640</td>\n",
              "      <td>-0.8663</td>\n",
              "      <td>0.8129</td>\n",
              "      <td>-0.1514</td>\n",
              "      <td>-0.4652</td>\n",
              "      <td>-0.7390</td>\n",
              "      <td>-1.3270</td>\n",
              "      <td>0.9925</td>\n",
              "      <td>1.0570</td>\n",
              "      <td>-0.3355</td>\n",
              "      <td>-0.2555</td>\n",
              "      <td>0.8219</td>\n",
              "      <td>0.6995</td>\n",
              "      <td>-0.2942</td>\n",
              "      <td>0.2408</td>\n",
              "      <td>-0.7781</td>\n",
              "      <td>-0.0929</td>\n",
              "      <td>-0.0329</td>\n",
              "      <td>0.0781</td>\n",
              "      <td>-1.4440</td>\n",
              "      <td>-0.0921</td>\n",
              "      <td>0.3188</td>\n",
              "      <td>-1.1080</td>\n",
              "      <td>0.4895</td>\n",
              "      <td>-0.2144</td>\n",
              "      <td>1.0960</td>\n",
              "      <td>0.3335</td>\n",
              "      <td>0.4444</td>\n",
              "      <td>-1.1130</td>\n",
              "      <td>0.4286</td>\n",
              "      <td>0.4426</td>\n",
              "      <td>0.0423</td>\n",
              "      <td>-0.3195</td>\n",
              "      <td>-0.8086</td>\n",
              "      <td>-0.9798</td>\n",
              "      <td>-0.2084</td>\n",
              "      <td>-0.1224</td>\n",
              "      <td>-0.2715</td>\n",
              "      <td>0.3689</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23811</th>\n",
              "      <td>id_fffc1c3f4</td>\n",
              "      <td>com_controle</td>\n",
              "      <td>48</td>\n",
              "      <td>D2</td>\n",
              "      <td>cacb2b860</td>\n",
              "      <td>0.3942</td>\n",
              "      <td>0.3756</td>\n",
              "      <td>0.3109</td>\n",
              "      <td>-0.7389</td>\n",
              "      <td>0.5505</td>\n",
              "      <td>-0.0159</td>\n",
              "      <td>-0.2541</td>\n",
              "      <td>0.1745</td>\n",
              "      <td>-0.0340</td>\n",
              "      <td>0.4865</td>\n",
              "      <td>-0.1854</td>\n",
              "      <td>0.0716</td>\n",
              "      <td>0.1729</td>\n",
              "      <td>-0.0434</td>\n",
              "      <td>0.1542</td>\n",
              "      <td>-0.2192</td>\n",
              "      <td>-0.0302</td>\n",
              "      <td>-0.4218</td>\n",
              "      <td>0.4057</td>\n",
              "      <td>-0.5372</td>\n",
              "      <td>0.1521</td>\n",
              "      <td>-0.2651</td>\n",
              "      <td>0.2310</td>\n",
              "      <td>-0.8101</td>\n",
              "      <td>0.4943</td>\n",
              "      <td>0.6905</td>\n",
              "      <td>-0.3720</td>\n",
              "      <td>-1.4110</td>\n",
              "      <td>0.4516</td>\n",
              "      <td>1.2300</td>\n",
              "      <td>-0.1949</td>\n",
              "      <td>-1.3280</td>\n",
              "      <td>-0.4276</td>\n",
              "      <td>-0.0040</td>\n",
              "      <td>-0.3086</td>\n",
              "      <td>...</td>\n",
              "      <td>0.6845</td>\n",
              "      <td>0.7127</td>\n",
              "      <td>0.7294</td>\n",
              "      <td>0.4718</td>\n",
              "      <td>-0.2020</td>\n",
              "      <td>0.2783</td>\n",
              "      <td>0.4934</td>\n",
              "      <td>0.4144</td>\n",
              "      <td>0.5449</td>\n",
              "      <td>1.4690</td>\n",
              "      <td>-0.6142</td>\n",
              "      <td>0.6068</td>\n",
              "      <td>0.3434</td>\n",
              "      <td>0.9880</td>\n",
              "      <td>-0.0468</td>\n",
              "      <td>-0.1882</td>\n",
              "      <td>-0.0087</td>\n",
              "      <td>-0.0356</td>\n",
              "      <td>0.5718</td>\n",
              "      <td>0.4971</td>\n",
              "      <td>0.1057</td>\n",
              "      <td>0.2111</td>\n",
              "      <td>0.6992</td>\n",
              "      <td>0.0708</td>\n",
              "      <td>0.6169</td>\n",
              "      <td>0.2248</td>\n",
              "      <td>0.5994</td>\n",
              "      <td>0.2689</td>\n",
              "      <td>0.0305</td>\n",
              "      <td>1.2320</td>\n",
              "      <td>0.5409</td>\n",
              "      <td>0.3755</td>\n",
              "      <td>0.7343</td>\n",
              "      <td>0.2807</td>\n",
              "      <td>0.4116</td>\n",
              "      <td>0.6422</td>\n",
              "      <td>0.2256</td>\n",
              "      <td>0.7592</td>\n",
              "      <td>0.6656</td>\n",
              "      <td>0.3808</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23812</th>\n",
              "      <td>id_fffcb9e7c</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D1</td>\n",
              "      <td>8b87a7a83</td>\n",
              "      <td>0.6660</td>\n",
              "      <td>0.2324</td>\n",
              "      <td>0.4392</td>\n",
              "      <td>0.2044</td>\n",
              "      <td>0.8531</td>\n",
              "      <td>-0.0343</td>\n",
              "      <td>0.0323</td>\n",
              "      <td>0.0463</td>\n",
              "      <td>0.4299</td>\n",
              "      <td>-0.7985</td>\n",
              "      <td>0.5742</td>\n",
              "      <td>0.1421</td>\n",
              "      <td>2.2700</td>\n",
              "      <td>0.2046</td>\n",
              "      <td>0.5363</td>\n",
              "      <td>-1.7330</td>\n",
              "      <td>0.1450</td>\n",
              "      <td>0.6097</td>\n",
              "      <td>0.2024</td>\n",
              "      <td>0.9865</td>\n",
              "      <td>-0.7805</td>\n",
              "      <td>0.9608</td>\n",
              "      <td>0.3440</td>\n",
              "      <td>2.7650</td>\n",
              "      <td>0.4925</td>\n",
              "      <td>0.6698</td>\n",
              "      <td>0.2374</td>\n",
              "      <td>-0.3372</td>\n",
              "      <td>0.8771</td>\n",
              "      <td>-2.6560</td>\n",
              "      <td>-0.2000</td>\n",
              "      <td>-0.2043</td>\n",
              "      <td>0.6797</td>\n",
              "      <td>-0.0248</td>\n",
              "      <td>-0.0927</td>\n",
              "      <td>...</td>\n",
              "      <td>0.3360</td>\n",
              "      <td>-0.6136</td>\n",
              "      <td>0.5011</td>\n",
              "      <td>0.9261</td>\n",
              "      <td>0.4419</td>\n",
              "      <td>0.0295</td>\n",
              "      <td>0.4220</td>\n",
              "      <td>0.4677</td>\n",
              "      <td>-0.1184</td>\n",
              "      <td>0.4524</td>\n",
              "      <td>0.4135</td>\n",
              "      <td>0.1356</td>\n",
              "      <td>-0.5801</td>\n",
              "      <td>0.0411</td>\n",
              "      <td>1.0240</td>\n",
              "      <td>1.0340</td>\n",
              "      <td>-0.0270</td>\n",
              "      <td>-0.4194</td>\n",
              "      <td>0.7403</td>\n",
              "      <td>-0.6793</td>\n",
              "      <td>-0.1423</td>\n",
              "      <td>0.7307</td>\n",
              "      <td>0.7946</td>\n",
              "      <td>-0.0650</td>\n",
              "      <td>0.9038</td>\n",
              "      <td>0.2324</td>\n",
              "      <td>0.9676</td>\n",
              "      <td>1.0940</td>\n",
              "      <td>0.4290</td>\n",
              "      <td>0.5187</td>\n",
              "      <td>-0.1105</td>\n",
              "      <td>0.4258</td>\n",
              "      <td>-0.2012</td>\n",
              "      <td>0.1506</td>\n",
              "      <td>1.5230</td>\n",
              "      <td>0.7101</td>\n",
              "      <td>0.1732</td>\n",
              "      <td>0.7015</td>\n",
              "      <td>-0.6290</td>\n",
              "      <td>0.0740</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23813</th>\n",
              "      <td>id_ffffdd77b</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D1</td>\n",
              "      <td>972f41291</td>\n",
              "      <td>-0.8598</td>\n",
              "      <td>1.0240</td>\n",
              "      <td>-0.1361</td>\n",
              "      <td>0.7952</td>\n",
              "      <td>-0.3611</td>\n",
              "      <td>-3.6750</td>\n",
              "      <td>-1.2420</td>\n",
              "      <td>0.9146</td>\n",
              "      <td>3.0790</td>\n",
              "      <td>1.2460</td>\n",
              "      <td>1.9460</td>\n",
              "      <td>1.4370</td>\n",
              "      <td>2.9780</td>\n",
              "      <td>2.2370</td>\n",
              "      <td>-0.6818</td>\n",
              "      <td>0.6870</td>\n",
              "      <td>-1.1060</td>\n",
              "      <td>0.0182</td>\n",
              "      <td>-0.9247</td>\n",
              "      <td>-0.0738</td>\n",
              "      <td>-0.1919</td>\n",
              "      <td>-0.7722</td>\n",
              "      <td>-1.4050</td>\n",
              "      <td>-1.0050</td>\n",
              "      <td>-1.1170</td>\n",
              "      <td>-0.5293</td>\n",
              "      <td>-1.1720</td>\n",
              "      <td>-0.2885</td>\n",
              "      <td>0.1599</td>\n",
              "      <td>-0.4250</td>\n",
              "      <td>0.3591</td>\n",
              "      <td>-0.1420</td>\n",
              "      <td>-0.9530</td>\n",
              "      <td>-0.2005</td>\n",
              "      <td>-1.8340</td>\n",
              "      <td>...</td>\n",
              "      <td>-6.9170</td>\n",
              "      <td>-1.8640</td>\n",
              "      <td>-2.5090</td>\n",
              "      <td>-4.7130</td>\n",
              "      <td>-1.7250</td>\n",
              "      <td>-3.8650</td>\n",
              "      <td>-3.0800</td>\n",
              "      <td>-4.1530</td>\n",
              "      <td>-1.2030</td>\n",
              "      <td>-1.1690</td>\n",
              "      <td>-4.1460</td>\n",
              "      <td>-1.2670</td>\n",
              "      <td>-1.1300</td>\n",
              "      <td>-2.4390</td>\n",
              "      <td>0.1591</td>\n",
              "      <td>-2.2490</td>\n",
              "      <td>-2.5860</td>\n",
              "      <td>-1.9520</td>\n",
              "      <td>-2.1810</td>\n",
              "      <td>-4.6690</td>\n",
              "      <td>-3.9450</td>\n",
              "      <td>-2.9560</td>\n",
              "      <td>-2.7930</td>\n",
              "      <td>-2.1560</td>\n",
              "      <td>-2.4100</td>\n",
              "      <td>-1.8190</td>\n",
              "      <td>-3.3480</td>\n",
              "      <td>-0.1414</td>\n",
              "      <td>-2.6430</td>\n",
              "      <td>-2.5810</td>\n",
              "      <td>-3.3890</td>\n",
              "      <td>-1.7450</td>\n",
              "      <td>-6.6300</td>\n",
              "      <td>-4.0950</td>\n",
              "      <td>-7.3860</td>\n",
              "      <td>-1.4160</td>\n",
              "      <td>-3.5770</td>\n",
              "      <td>-0.4775</td>\n",
              "      <td>-2.1500</td>\n",
              "      <td>-4.2520</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>23814 rows × 877 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "                 id    tratamento  tempo dose  ...    c-96    c-97    c-98    c-99\n",
              "0      id_000644bb2     com_droga     24   D1  ... -0.3981  0.2139  0.3801  0.4176\n",
              "1      id_000779bfc     com_droga     72   D1  ...  0.1522  0.1241  0.6077  0.7371\n",
              "2      id_000a6266a     com_droga     48   D1  ... -0.6417 -0.2187 -1.4080  0.6931\n",
              "3      id_0015fd391     com_droga     48   D1  ... -1.6210 -0.8784 -0.3876 -0.8154\n",
              "4      id_001626bd3     com_droga     72   D2  ...  0.1094  0.2885 -0.3786  0.7125\n",
              "...             ...           ...    ...  ...  ...     ...     ...     ...     ...\n",
              "23809  id_fffb1ceed     com_droga     24   D2  ...  0.0631  0.9171  0.5258  0.4680\n",
              "23810  id_fffb70c0c     com_droga     24   D2  ... -0.2084 -0.1224 -0.2715  0.3689\n",
              "23811  id_fffc1c3f4  com_controle     48   D2  ...  0.2256  0.7592  0.6656  0.3808\n",
              "23812  id_fffcb9e7c     com_droga     24   D1  ...  0.1732  0.7015 -0.6290  0.0740\n",
              "23813  id_ffffdd77b     com_droga     72   D1  ... -3.5770 -0.4775 -2.1500 -4.2520\n",
              "\n",
              "[23814 rows x 877 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 1
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 435
        },
        "id": "4uID_GX603i-",
        "outputId": "e5b4a10e-d268-4316-ef65-e97a5cbb14d9"
      },
      "source": [
        "mapa = {'droga': 'composto'}\n",
        "dados.rename(columns=mapa, inplace=True)\n",
        "dados"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>tratamento</th>\n",
              "      <th>tempo</th>\n",
              "      <th>dose</th>\n",
              "      <th>composto</th>\n",
              "      <th>g-0</th>\n",
              "      <th>g-1</th>\n",
              "      <th>g-2</th>\n",
              "      <th>g-3</th>\n",
              "      <th>g-4</th>\n",
              "      <th>g-5</th>\n",
              "      <th>g-6</th>\n",
              "      <th>g-7</th>\n",
              "      <th>g-8</th>\n",
              "      <th>g-9</th>\n",
              "      <th>g-10</th>\n",
              "      <th>g-11</th>\n",
              "      <th>g-12</th>\n",
              "      <th>g-13</th>\n",
              "      <th>g-14</th>\n",
              "      <th>g-15</th>\n",
              "      <th>g-16</th>\n",
              "      <th>g-17</th>\n",
              "      <th>g-18</th>\n",
              "      <th>g-19</th>\n",
              "      <th>g-20</th>\n",
              "      <th>g-21</th>\n",
              "      <th>g-22</th>\n",
              "      <th>g-23</th>\n",
              "      <th>g-24</th>\n",
              "      <th>g-25</th>\n",
              "      <th>g-26</th>\n",
              "      <th>g-27</th>\n",
              "      <th>g-28</th>\n",
              "      <th>g-29</th>\n",
              "      <th>g-30</th>\n",
              "      <th>g-31</th>\n",
              "      <th>g-32</th>\n",
              "      <th>g-33</th>\n",
              "      <th>g-34</th>\n",
              "      <th>...</th>\n",
              "      <th>c-60</th>\n",
              "      <th>c-61</th>\n",
              "      <th>c-62</th>\n",
              "      <th>c-63</th>\n",
              "      <th>c-64</th>\n",
              "      <th>c-65</th>\n",
              "      <th>c-66</th>\n",
              "      <th>c-67</th>\n",
              "      <th>c-68</th>\n",
              "      <th>c-69</th>\n",
              "      <th>c-70</th>\n",
              "      <th>c-71</th>\n",
              "      <th>c-72</th>\n",
              "      <th>c-73</th>\n",
              "      <th>c-74</th>\n",
              "      <th>c-75</th>\n",
              "      <th>c-76</th>\n",
              "      <th>c-77</th>\n",
              "      <th>c-78</th>\n",
              "      <th>c-79</th>\n",
              "      <th>c-80</th>\n",
              "      <th>c-81</th>\n",
              "      <th>c-82</th>\n",
              "      <th>c-83</th>\n",
              "      <th>c-84</th>\n",
              "      <th>c-85</th>\n",
              "      <th>c-86</th>\n",
              "      <th>c-87</th>\n",
              "      <th>c-88</th>\n",
              "      <th>c-89</th>\n",
              "      <th>c-90</th>\n",
              "      <th>c-91</th>\n",
              "      <th>c-92</th>\n",
              "      <th>c-93</th>\n",
              "      <th>c-94</th>\n",
              "      <th>c-95</th>\n",
              "      <th>c-96</th>\n",
              "      <th>c-97</th>\n",
              "      <th>c-98</th>\n",
              "      <th>c-99</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D1</td>\n",
              "      <td>b68db1d53</td>\n",
              "      <td>1.0620</td>\n",
              "      <td>0.5577</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-0.6208</td>\n",
              "      <td>-0.1944</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>-1.0220</td>\n",
              "      <td>-0.0326</td>\n",
              "      <td>0.5548</td>\n",
              "      <td>-0.0921</td>\n",
              "      <td>1.1830</td>\n",
              "      <td>0.1530</td>\n",
              "      <td>0.5574</td>\n",
              "      <td>-0.4015</td>\n",
              "      <td>0.1789</td>\n",
              "      <td>-0.6528</td>\n",
              "      <td>-0.7969</td>\n",
              "      <td>0.6342</td>\n",
              "      <td>0.1778</td>\n",
              "      <td>-0.3694</td>\n",
              "      <td>-0.5688</td>\n",
              "      <td>-1.1360</td>\n",
              "      <td>-1.1880</td>\n",
              "      <td>0.6940</td>\n",
              "      <td>0.4393</td>\n",
              "      <td>0.2664</td>\n",
              "      <td>0.1907</td>\n",
              "      <td>0.1628</td>\n",
              "      <td>-0.2853</td>\n",
              "      <td>0.5819</td>\n",
              "      <td>0.2934</td>\n",
              "      <td>-0.5584</td>\n",
              "      <td>-0.0916</td>\n",
              "      <td>-0.3010</td>\n",
              "      <td>-0.1537</td>\n",
              "      <td>...</td>\n",
              "      <td>0.4805</td>\n",
              "      <td>0.4965</td>\n",
              "      <td>0.3680</td>\n",
              "      <td>0.8427</td>\n",
              "      <td>0.1042</td>\n",
              "      <td>0.1403</td>\n",
              "      <td>0.1758</td>\n",
              "      <td>1.2570</td>\n",
              "      <td>-0.5979</td>\n",
              "      <td>1.2250</td>\n",
              "      <td>-0.0553</td>\n",
              "      <td>0.7351</td>\n",
              "      <td>0.5810</td>\n",
              "      <td>0.9590</td>\n",
              "      <td>0.2427</td>\n",
              "      <td>0.0495</td>\n",
              "      <td>0.4141</td>\n",
              "      <td>0.8432</td>\n",
              "      <td>0.6162</td>\n",
              "      <td>-0.7318</td>\n",
              "      <td>1.2120</td>\n",
              "      <td>0.6362</td>\n",
              "      <td>-0.4427</td>\n",
              "      <td>0.1288</td>\n",
              "      <td>1.4840</td>\n",
              "      <td>0.1799</td>\n",
              "      <td>0.5367</td>\n",
              "      <td>-0.1111</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>0.6685</td>\n",
              "      <td>0.2862</td>\n",
              "      <td>0.2584</td>\n",
              "      <td>0.8076</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.1912</td>\n",
              "      <td>0.6584</td>\n",
              "      <td>-0.3981</td>\n",
              "      <td>0.2139</td>\n",
              "      <td>0.3801</td>\n",
              "      <td>0.4176</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D1</td>\n",
              "      <td>df89a8e5a</td>\n",
              "      <td>0.0743</td>\n",
              "      <td>0.4087</td>\n",
              "      <td>0.2991</td>\n",
              "      <td>0.0604</td>\n",
              "      <td>1.0190</td>\n",
              "      <td>0.5207</td>\n",
              "      <td>0.2341</td>\n",
              "      <td>0.3372</td>\n",
              "      <td>-0.4047</td>\n",
              "      <td>0.8507</td>\n",
              "      <td>-1.1520</td>\n",
              "      <td>-0.4201</td>\n",
              "      <td>-0.0958</td>\n",
              "      <td>0.4590</td>\n",
              "      <td>0.0803</td>\n",
              "      <td>0.2250</td>\n",
              "      <td>0.5293</td>\n",
              "      <td>0.2839</td>\n",
              "      <td>-0.3494</td>\n",
              "      <td>0.2883</td>\n",
              "      <td>0.9449</td>\n",
              "      <td>-0.1646</td>\n",
              "      <td>-0.2657</td>\n",
              "      <td>-0.3372</td>\n",
              "      <td>0.3135</td>\n",
              "      <td>-0.4316</td>\n",
              "      <td>0.4773</td>\n",
              "      <td>0.2075</td>\n",
              "      <td>-0.4216</td>\n",
              "      <td>-0.1161</td>\n",
              "      <td>-0.0499</td>\n",
              "      <td>-0.2627</td>\n",
              "      <td>0.9959</td>\n",
              "      <td>-0.2483</td>\n",
              "      <td>0.2655</td>\n",
              "      <td>...</td>\n",
              "      <td>0.4083</td>\n",
              "      <td>0.0319</td>\n",
              "      <td>0.3905</td>\n",
              "      <td>0.7099</td>\n",
              "      <td>0.2912</td>\n",
              "      <td>0.4151</td>\n",
              "      <td>-0.2840</td>\n",
              "      <td>-0.3104</td>\n",
              "      <td>-0.6373</td>\n",
              "      <td>0.2887</td>\n",
              "      <td>-0.0765</td>\n",
              "      <td>0.2539</td>\n",
              "      <td>0.4443</td>\n",
              "      <td>0.5932</td>\n",
              "      <td>0.2031</td>\n",
              "      <td>0.7639</td>\n",
              "      <td>0.5499</td>\n",
              "      <td>-0.3322</td>\n",
              "      <td>-0.0977</td>\n",
              "      <td>0.4329</td>\n",
              "      <td>-0.2782</td>\n",
              "      <td>0.7827</td>\n",
              "      <td>0.5934</td>\n",
              "      <td>0.3402</td>\n",
              "      <td>0.1499</td>\n",
              "      <td>0.4420</td>\n",
              "      <td>0.9366</td>\n",
              "      <td>0.8193</td>\n",
              "      <td>-0.4236</td>\n",
              "      <td>0.3192</td>\n",
              "      <td>-0.4265</td>\n",
              "      <td>0.7543</td>\n",
              "      <td>0.4708</td>\n",
              "      <td>0.0230</td>\n",
              "      <td>0.2957</td>\n",
              "      <td>0.4899</td>\n",
              "      <td>0.1522</td>\n",
              "      <td>0.1241</td>\n",
              "      <td>0.6077</td>\n",
              "      <td>0.7371</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>48</td>\n",
              "      <td>D1</td>\n",
              "      <td>18bb41b2c</td>\n",
              "      <td>0.6280</td>\n",
              "      <td>0.5817</td>\n",
              "      <td>1.5540</td>\n",
              "      <td>-0.0764</td>\n",
              "      <td>-0.0323</td>\n",
              "      <td>1.2390</td>\n",
              "      <td>0.1715</td>\n",
              "      <td>0.2155</td>\n",
              "      <td>0.0065</td>\n",
              "      <td>1.2300</td>\n",
              "      <td>-0.4797</td>\n",
              "      <td>-0.5631</td>\n",
              "      <td>-0.0366</td>\n",
              "      <td>-1.8300</td>\n",
              "      <td>0.6057</td>\n",
              "      <td>-0.3278</td>\n",
              "      <td>0.6042</td>\n",
              "      <td>-0.3075</td>\n",
              "      <td>-0.1147</td>\n",
              "      <td>-0.0570</td>\n",
              "      <td>-0.0799</td>\n",
              "      <td>-0.8181</td>\n",
              "      <td>-1.5320</td>\n",
              "      <td>0.2307</td>\n",
              "      <td>0.4901</td>\n",
              "      <td>0.4780</td>\n",
              "      <td>-1.3970</td>\n",
              "      <td>4.6240</td>\n",
              "      <td>-0.0437</td>\n",
              "      <td>1.2870</td>\n",
              "      <td>-1.8530</td>\n",
              "      <td>0.6069</td>\n",
              "      <td>0.4290</td>\n",
              "      <td>0.1783</td>\n",
              "      <td>0.0018</td>\n",
              "      <td>...</td>\n",
              "      <td>-0.5477</td>\n",
              "      <td>-0.7576</td>\n",
              "      <td>-0.0444</td>\n",
              "      <td>0.1894</td>\n",
              "      <td>-0.0014</td>\n",
              "      <td>-2.3640</td>\n",
              "      <td>-0.4682</td>\n",
              "      <td>0.1210</td>\n",
              "      <td>-0.5177</td>\n",
              "      <td>-0.0604</td>\n",
              "      <td>0.1682</td>\n",
              "      <td>-0.4436</td>\n",
              "      <td>0.4963</td>\n",
              "      <td>0.1363</td>\n",
              "      <td>0.3335</td>\n",
              "      <td>0.9760</td>\n",
              "      <td>-0.0427</td>\n",
              "      <td>-0.1235</td>\n",
              "      <td>0.0959</td>\n",
              "      <td>0.0690</td>\n",
              "      <td>-0.9416</td>\n",
              "      <td>-0.7548</td>\n",
              "      <td>-0.1109</td>\n",
              "      <td>-0.6272</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>0.1172</td>\n",
              "      <td>0.1093</td>\n",
              "      <td>-0.3113</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>-0.0873</td>\n",
              "      <td>-0.7250</td>\n",
              "      <td>-0.6297</td>\n",
              "      <td>0.6103</td>\n",
              "      <td>0.0223</td>\n",
              "      <td>-1.3240</td>\n",
              "      <td>-0.3174</td>\n",
              "      <td>-0.6417</td>\n",
              "      <td>-0.2187</td>\n",
              "      <td>-1.4080</td>\n",
              "      <td>0.6931</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>48</td>\n",
              "      <td>D1</td>\n",
              "      <td>8c7f86626</td>\n",
              "      <td>-0.5138</td>\n",
              "      <td>-0.2491</td>\n",
              "      <td>-0.2656</td>\n",
              "      <td>0.5288</td>\n",
              "      <td>4.0620</td>\n",
              "      <td>-0.8095</td>\n",
              "      <td>-1.9590</td>\n",
              "      <td>0.1792</td>\n",
              "      <td>-0.1321</td>\n",
              "      <td>-1.0600</td>\n",
              "      <td>-0.8269</td>\n",
              "      <td>-0.3584</td>\n",
              "      <td>-0.8511</td>\n",
              "      <td>-0.5844</td>\n",
              "      <td>-2.5690</td>\n",
              "      <td>0.8183</td>\n",
              "      <td>-0.0532</td>\n",
              "      <td>-0.8554</td>\n",
              "      <td>0.1160</td>\n",
              "      <td>-2.3520</td>\n",
              "      <td>2.1200</td>\n",
              "      <td>-1.1580</td>\n",
              "      <td>-0.7191</td>\n",
              "      <td>-0.8004</td>\n",
              "      <td>-1.4670</td>\n",
              "      <td>-0.0107</td>\n",
              "      <td>-0.8995</td>\n",
              "      <td>0.2406</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-1.0890</td>\n",
              "      <td>-0.7575</td>\n",
              "      <td>0.0881</td>\n",
              "      <td>-2.7370</td>\n",
              "      <td>0.8745</td>\n",
              "      <td>0.5787</td>\n",
              "      <td>...</td>\n",
              "      <td>-2.1220</td>\n",
              "      <td>-0.3752</td>\n",
              "      <td>-2.3820</td>\n",
              "      <td>-3.7350</td>\n",
              "      <td>-2.9740</td>\n",
              "      <td>-1.4930</td>\n",
              "      <td>-1.6600</td>\n",
              "      <td>-3.1660</td>\n",
              "      <td>0.2816</td>\n",
              "      <td>-0.2990</td>\n",
              "      <td>-1.1870</td>\n",
              "      <td>-0.5044</td>\n",
              "      <td>-1.7750</td>\n",
              "      <td>-1.6120</td>\n",
              "      <td>-0.9215</td>\n",
              "      <td>-1.0810</td>\n",
              "      <td>-3.0520</td>\n",
              "      <td>-3.4470</td>\n",
              "      <td>-2.7740</td>\n",
              "      <td>-1.8460</td>\n",
              "      <td>-0.5568</td>\n",
              "      <td>-3.3960</td>\n",
              "      <td>-2.9510</td>\n",
              "      <td>-1.1550</td>\n",
              "      <td>-3.2620</td>\n",
              "      <td>-1.5390</td>\n",
              "      <td>-2.4600</td>\n",
              "      <td>-0.9417</td>\n",
              "      <td>-1.5550</td>\n",
              "      <td>0.2431</td>\n",
              "      <td>-2.0990</td>\n",
              "      <td>-0.6441</td>\n",
              "      <td>-5.6300</td>\n",
              "      <td>-1.3780</td>\n",
              "      <td>-0.8632</td>\n",
              "      <td>-1.2880</td>\n",
              "      <td>-1.6210</td>\n",
              "      <td>-0.8784</td>\n",
              "      <td>-0.3876</td>\n",
              "      <td>-0.8154</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D2</td>\n",
              "      <td>7cbed3131</td>\n",
              "      <td>-0.3254</td>\n",
              "      <td>-0.4009</td>\n",
              "      <td>0.9700</td>\n",
              "      <td>0.6919</td>\n",
              "      <td>1.4180</td>\n",
              "      <td>-0.8244</td>\n",
              "      <td>-0.2800</td>\n",
              "      <td>-0.1498</td>\n",
              "      <td>-0.8789</td>\n",
              "      <td>0.8630</td>\n",
              "      <td>-0.2219</td>\n",
              "      <td>-0.5121</td>\n",
              "      <td>-0.9577</td>\n",
              "      <td>1.1750</td>\n",
              "      <td>0.2042</td>\n",
              "      <td>0.1970</td>\n",
              "      <td>0.1244</td>\n",
              "      <td>-1.7090</td>\n",
              "      <td>-0.3543</td>\n",
              "      <td>-0.5160</td>\n",
              "      <td>-0.3330</td>\n",
              "      <td>-0.2685</td>\n",
              "      <td>0.7649</td>\n",
              "      <td>0.2057</td>\n",
              "      <td>1.3720</td>\n",
              "      <td>0.6835</td>\n",
              "      <td>0.8056</td>\n",
              "      <td>-0.3754</td>\n",
              "      <td>-1.2090</td>\n",
              "      <td>0.2965</td>\n",
              "      <td>-0.0712</td>\n",
              "      <td>0.6389</td>\n",
              "      <td>0.6674</td>\n",
              "      <td>-0.0783</td>\n",
              "      <td>1.1740</td>\n",
              "      <td>...</td>\n",
              "      <td>-0.2274</td>\n",
              "      <td>0.3215</td>\n",
              "      <td>0.1535</td>\n",
              "      <td>-0.4640</td>\n",
              "      <td>-0.5943</td>\n",
              "      <td>0.3973</td>\n",
              "      <td>0.1500</td>\n",
              "      <td>0.5178</td>\n",
              "      <td>0.5159</td>\n",
              "      <td>0.6091</td>\n",
              "      <td>0.1813</td>\n",
              "      <td>-0.4249</td>\n",
              "      <td>0.7832</td>\n",
              "      <td>0.6529</td>\n",
              "      <td>0.5648</td>\n",
              "      <td>0.4817</td>\n",
              "      <td>0.0587</td>\n",
              "      <td>0.5303</td>\n",
              "      <td>0.6376</td>\n",
              "      <td>-0.3966</td>\n",
              "      <td>-1.4950</td>\n",
              "      <td>-0.9625</td>\n",
              "      <td>-0.0541</td>\n",
              "      <td>0.6273</td>\n",
              "      <td>0.4563</td>\n",
              "      <td>0.0698</td>\n",
              "      <td>0.8134</td>\n",
              "      <td>0.1924</td>\n",
              "      <td>0.6054</td>\n",
              "      <td>-0.1824</td>\n",
              "      <td>0.0042</td>\n",
              "      <td>0.0048</td>\n",
              "      <td>0.6670</td>\n",
              "      <td>1.0690</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.3031</td>\n",
              "      <td>0.1094</td>\n",
              "      <td>0.2885</td>\n",
              "      <td>-0.3786</td>\n",
              "      <td>0.7125</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>...</th>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23809</th>\n",
              "      <td>id_fffb1ceed</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D2</td>\n",
              "      <td>df1d0a5a1</td>\n",
              "      <td>0.1394</td>\n",
              "      <td>-0.0636</td>\n",
              "      <td>-0.1112</td>\n",
              "      <td>-0.5080</td>\n",
              "      <td>-0.4713</td>\n",
              "      <td>0.7201</td>\n",
              "      <td>0.5773</td>\n",
              "      <td>0.3055</td>\n",
              "      <td>-0.4726</td>\n",
              "      <td>0.1269</td>\n",
              "      <td>0.2531</td>\n",
              "      <td>0.1730</td>\n",
              "      <td>-0.4532</td>\n",
              "      <td>-1.0790</td>\n",
              "      <td>0.2474</td>\n",
              "      <td>-0.4550</td>\n",
              "      <td>0.3588</td>\n",
              "      <td>0.1600</td>\n",
              "      <td>-0.7362</td>\n",
              "      <td>-0.1103</td>\n",
              "      <td>0.8550</td>\n",
              "      <td>-0.4139</td>\n",
              "      <td>0.5541</td>\n",
              "      <td>0.2310</td>\n",
              "      <td>-0.5573</td>\n",
              "      <td>-0.4397</td>\n",
              "      <td>-0.9260</td>\n",
              "      <td>-0.2424</td>\n",
              "      <td>-0.6686</td>\n",
              "      <td>0.2326</td>\n",
              "      <td>0.6456</td>\n",
              "      <td>0.0136</td>\n",
              "      <td>-0.5141</td>\n",
              "      <td>-0.6320</td>\n",
              "      <td>0.7166</td>\n",
              "      <td>...</td>\n",
              "      <td>0.0807</td>\n",
              "      <td>0.4024</td>\n",
              "      <td>-0.0895</td>\n",
              "      <td>0.4420</td>\n",
              "      <td>0.9641</td>\n",
              "      <td>-0.1846</td>\n",
              "      <td>-0.0014</td>\n",
              "      <td>0.3154</td>\n",
              "      <td>-0.2071</td>\n",
              "      <td>-0.6158</td>\n",
              "      <td>-0.2977</td>\n",
              "      <td>0.0992</td>\n",
              "      <td>0.6838</td>\n",
              "      <td>0.5259</td>\n",
              "      <td>0.7882</td>\n",
              "      <td>0.3119</td>\n",
              "      <td>-0.7697</td>\n",
              "      <td>0.2203</td>\n",
              "      <td>-1.0710</td>\n",
              "      <td>0.5979</td>\n",
              "      <td>0.0848</td>\n",
              "      <td>-0.2555</td>\n",
              "      <td>0.6293</td>\n",
              "      <td>1.1660</td>\n",
              "      <td>0.3329</td>\n",
              "      <td>0.2754</td>\n",
              "      <td>0.4108</td>\n",
              "      <td>-0.1252</td>\n",
              "      <td>-0.2340</td>\n",
              "      <td>0.2267</td>\n",
              "      <td>0.1969</td>\n",
              "      <td>0.0262</td>\n",
              "      <td>-0.8121</td>\n",
              "      <td>0.3434</td>\n",
              "      <td>0.5372</td>\n",
              "      <td>-0.3246</td>\n",
              "      <td>0.0631</td>\n",
              "      <td>0.9171</td>\n",
              "      <td>0.5258</td>\n",
              "      <td>0.4680</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23810</th>\n",
              "      <td>id_fffb70c0c</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D2</td>\n",
              "      <td>ecf3b6b74</td>\n",
              "      <td>-1.3260</td>\n",
              "      <td>0.3478</td>\n",
              "      <td>-0.3743</td>\n",
              "      <td>0.9905</td>\n",
              "      <td>-0.7178</td>\n",
              "      <td>0.6621</td>\n",
              "      <td>-0.2252</td>\n",
              "      <td>-0.5565</td>\n",
              "      <td>0.5112</td>\n",
              "      <td>0.6727</td>\n",
              "      <td>-0.1851</td>\n",
              "      <td>2.8650</td>\n",
              "      <td>-0.2140</td>\n",
              "      <td>-0.6153</td>\n",
              "      <td>0.8362</td>\n",
              "      <td>0.5584</td>\n",
              "      <td>-0.2589</td>\n",
              "      <td>0.1292</td>\n",
              "      <td>0.0148</td>\n",
              "      <td>0.0949</td>\n",
              "      <td>-0.2182</td>\n",
              "      <td>-0.9235</td>\n",
              "      <td>0.0749</td>\n",
              "      <td>-1.5910</td>\n",
              "      <td>-0.8359</td>\n",
              "      <td>-0.9217</td>\n",
              "      <td>0.3013</td>\n",
              "      <td>0.1716</td>\n",
              "      <td>0.0880</td>\n",
              "      <td>0.1842</td>\n",
              "      <td>0.1835</td>\n",
              "      <td>0.5436</td>\n",
              "      <td>-0.0533</td>\n",
              "      <td>-0.0491</td>\n",
              "      <td>0.9543</td>\n",
              "      <td>...</td>\n",
              "      <td>0.1410</td>\n",
              "      <td>1.2640</td>\n",
              "      <td>-0.8663</td>\n",
              "      <td>0.8129</td>\n",
              "      <td>-0.1514</td>\n",
              "      <td>-0.4652</td>\n",
              "      <td>-0.7390</td>\n",
              "      <td>-1.3270</td>\n",
              "      <td>0.9925</td>\n",
              "      <td>1.0570</td>\n",
              "      <td>-0.3355</td>\n",
              "      <td>-0.2555</td>\n",
              "      <td>0.8219</td>\n",
              "      <td>0.6995</td>\n",
              "      <td>-0.2942</td>\n",
              "      <td>0.2408</td>\n",
              "      <td>-0.7781</td>\n",
              "      <td>-0.0929</td>\n",
              "      <td>-0.0329</td>\n",
              "      <td>0.0781</td>\n",
              "      <td>-1.4440</td>\n",
              "      <td>-0.0921</td>\n",
              "      <td>0.3188</td>\n",
              "      <td>-1.1080</td>\n",
              "      <td>0.4895</td>\n",
              "      <td>-0.2144</td>\n",
              "      <td>1.0960</td>\n",
              "      <td>0.3335</td>\n",
              "      <td>0.4444</td>\n",
              "      <td>-1.1130</td>\n",
              "      <td>0.4286</td>\n",
              "      <td>0.4426</td>\n",
              "      <td>0.0423</td>\n",
              "      <td>-0.3195</td>\n",
              "      <td>-0.8086</td>\n",
              "      <td>-0.9798</td>\n",
              "      <td>-0.2084</td>\n",
              "      <td>-0.1224</td>\n",
              "      <td>-0.2715</td>\n",
              "      <td>0.3689</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23811</th>\n",
              "      <td>id_fffc1c3f4</td>\n",
              "      <td>com_controle</td>\n",
              "      <td>48</td>\n",
              "      <td>D2</td>\n",
              "      <td>cacb2b860</td>\n",
              "      <td>0.3942</td>\n",
              "      <td>0.3756</td>\n",
              "      <td>0.3109</td>\n",
              "      <td>-0.7389</td>\n",
              "      <td>0.5505</td>\n",
              "      <td>-0.0159</td>\n",
              "      <td>-0.2541</td>\n",
              "      <td>0.1745</td>\n",
              "      <td>-0.0340</td>\n",
              "      <td>0.4865</td>\n",
              "      <td>-0.1854</td>\n",
              "      <td>0.0716</td>\n",
              "      <td>0.1729</td>\n",
              "      <td>-0.0434</td>\n",
              "      <td>0.1542</td>\n",
              "      <td>-0.2192</td>\n",
              "      <td>-0.0302</td>\n",
              "      <td>-0.4218</td>\n",
              "      <td>0.4057</td>\n",
              "      <td>-0.5372</td>\n",
              "      <td>0.1521</td>\n",
              "      <td>-0.2651</td>\n",
              "      <td>0.2310</td>\n",
              "      <td>-0.8101</td>\n",
              "      <td>0.4943</td>\n",
              "      <td>0.6905</td>\n",
              "      <td>-0.3720</td>\n",
              "      <td>-1.4110</td>\n",
              "      <td>0.4516</td>\n",
              "      <td>1.2300</td>\n",
              "      <td>-0.1949</td>\n",
              "      <td>-1.3280</td>\n",
              "      <td>-0.4276</td>\n",
              "      <td>-0.0040</td>\n",
              "      <td>-0.3086</td>\n",
              "      <td>...</td>\n",
              "      <td>0.6845</td>\n",
              "      <td>0.7127</td>\n",
              "      <td>0.7294</td>\n",
              "      <td>0.4718</td>\n",
              "      <td>-0.2020</td>\n",
              "      <td>0.2783</td>\n",
              "      <td>0.4934</td>\n",
              "      <td>0.4144</td>\n",
              "      <td>0.5449</td>\n",
              "      <td>1.4690</td>\n",
              "      <td>-0.6142</td>\n",
              "      <td>0.6068</td>\n",
              "      <td>0.3434</td>\n",
              "      <td>0.9880</td>\n",
              "      <td>-0.0468</td>\n",
              "      <td>-0.1882</td>\n",
              "      <td>-0.0087</td>\n",
              "      <td>-0.0356</td>\n",
              "      <td>0.5718</td>\n",
              "      <td>0.4971</td>\n",
              "      <td>0.1057</td>\n",
              "      <td>0.2111</td>\n",
              "      <td>0.6992</td>\n",
              "      <td>0.0708</td>\n",
              "      <td>0.6169</td>\n",
              "      <td>0.2248</td>\n",
              "      <td>0.5994</td>\n",
              "      <td>0.2689</td>\n",
              "      <td>0.0305</td>\n",
              "      <td>1.2320</td>\n",
              "      <td>0.5409</td>\n",
              "      <td>0.3755</td>\n",
              "      <td>0.7343</td>\n",
              "      <td>0.2807</td>\n",
              "      <td>0.4116</td>\n",
              "      <td>0.6422</td>\n",
              "      <td>0.2256</td>\n",
              "      <td>0.7592</td>\n",
              "      <td>0.6656</td>\n",
              "      <td>0.3808</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23812</th>\n",
              "      <td>id_fffcb9e7c</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D1</td>\n",
              "      <td>8b87a7a83</td>\n",
              "      <td>0.6660</td>\n",
              "      <td>0.2324</td>\n",
              "      <td>0.4392</td>\n",
              "      <td>0.2044</td>\n",
              "      <td>0.8531</td>\n",
              "      <td>-0.0343</td>\n",
              "      <td>0.0323</td>\n",
              "      <td>0.0463</td>\n",
              "      <td>0.4299</td>\n",
              "      <td>-0.7985</td>\n",
              "      <td>0.5742</td>\n",
              "      <td>0.1421</td>\n",
              "      <td>2.2700</td>\n",
              "      <td>0.2046</td>\n",
              "      <td>0.5363</td>\n",
              "      <td>-1.7330</td>\n",
              "      <td>0.1450</td>\n",
              "      <td>0.6097</td>\n",
              "      <td>0.2024</td>\n",
              "      <td>0.9865</td>\n",
              "      <td>-0.7805</td>\n",
              "      <td>0.9608</td>\n",
              "      <td>0.3440</td>\n",
              "      <td>2.7650</td>\n",
              "      <td>0.4925</td>\n",
              "      <td>0.6698</td>\n",
              "      <td>0.2374</td>\n",
              "      <td>-0.3372</td>\n",
              "      <td>0.8771</td>\n",
              "      <td>-2.6560</td>\n",
              "      <td>-0.2000</td>\n",
              "      <td>-0.2043</td>\n",
              "      <td>0.6797</td>\n",
              "      <td>-0.0248</td>\n",
              "      <td>-0.0927</td>\n",
              "      <td>...</td>\n",
              "      <td>0.3360</td>\n",
              "      <td>-0.6136</td>\n",
              "      <td>0.5011</td>\n",
              "      <td>0.9261</td>\n",
              "      <td>0.4419</td>\n",
              "      <td>0.0295</td>\n",
              "      <td>0.4220</td>\n",
              "      <td>0.4677</td>\n",
              "      <td>-0.1184</td>\n",
              "      <td>0.4524</td>\n",
              "      <td>0.4135</td>\n",
              "      <td>0.1356</td>\n",
              "      <td>-0.5801</td>\n",
              "      <td>0.0411</td>\n",
              "      <td>1.0240</td>\n",
              "      <td>1.0340</td>\n",
              "      <td>-0.0270</td>\n",
              "      <td>-0.4194</td>\n",
              "      <td>0.7403</td>\n",
              "      <td>-0.6793</td>\n",
              "      <td>-0.1423</td>\n",
              "      <td>0.7307</td>\n",
              "      <td>0.7946</td>\n",
              "      <td>-0.0650</td>\n",
              "      <td>0.9038</td>\n",
              "      <td>0.2324</td>\n",
              "      <td>0.9676</td>\n",
              "      <td>1.0940</td>\n",
              "      <td>0.4290</td>\n",
              "      <td>0.5187</td>\n",
              "      <td>-0.1105</td>\n",
              "      <td>0.4258</td>\n",
              "      <td>-0.2012</td>\n",
              "      <td>0.1506</td>\n",
              "      <td>1.5230</td>\n",
              "      <td>0.7101</td>\n",
              "      <td>0.1732</td>\n",
              "      <td>0.7015</td>\n",
              "      <td>-0.6290</td>\n",
              "      <td>0.0740</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23813</th>\n",
              "      <td>id_ffffdd77b</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D1</td>\n",
              "      <td>972f41291</td>\n",
              "      <td>-0.8598</td>\n",
              "      <td>1.0240</td>\n",
              "      <td>-0.1361</td>\n",
              "      <td>0.7952</td>\n",
              "      <td>-0.3611</td>\n",
              "      <td>-3.6750</td>\n",
              "      <td>-1.2420</td>\n",
              "      <td>0.9146</td>\n",
              "      <td>3.0790</td>\n",
              "      <td>1.2460</td>\n",
              "      <td>1.9460</td>\n",
              "      <td>1.4370</td>\n",
              "      <td>2.9780</td>\n",
              "      <td>2.2370</td>\n",
              "      <td>-0.6818</td>\n",
              "      <td>0.6870</td>\n",
              "      <td>-1.1060</td>\n",
              "      <td>0.0182</td>\n",
              "      <td>-0.9247</td>\n",
              "      <td>-0.0738</td>\n",
              "      <td>-0.1919</td>\n",
              "      <td>-0.7722</td>\n",
              "      <td>-1.4050</td>\n",
              "      <td>-1.0050</td>\n",
              "      <td>-1.1170</td>\n",
              "      <td>-0.5293</td>\n",
              "      <td>-1.1720</td>\n",
              "      <td>-0.2885</td>\n",
              "      <td>0.1599</td>\n",
              "      <td>-0.4250</td>\n",
              "      <td>0.3591</td>\n",
              "      <td>-0.1420</td>\n",
              "      <td>-0.9530</td>\n",
              "      <td>-0.2005</td>\n",
              "      <td>-1.8340</td>\n",
              "      <td>...</td>\n",
              "      <td>-6.9170</td>\n",
              "      <td>-1.8640</td>\n",
              "      <td>-2.5090</td>\n",
              "      <td>-4.7130</td>\n",
              "      <td>-1.7250</td>\n",
              "      <td>-3.8650</td>\n",
              "      <td>-3.0800</td>\n",
              "      <td>-4.1530</td>\n",
              "      <td>-1.2030</td>\n",
              "      <td>-1.1690</td>\n",
              "      <td>-4.1460</td>\n",
              "      <td>-1.2670</td>\n",
              "      <td>-1.1300</td>\n",
              "      <td>-2.4390</td>\n",
              "      <td>0.1591</td>\n",
              "      <td>-2.2490</td>\n",
              "      <td>-2.5860</td>\n",
              "      <td>-1.9520</td>\n",
              "      <td>-2.1810</td>\n",
              "      <td>-4.6690</td>\n",
              "      <td>-3.9450</td>\n",
              "      <td>-2.9560</td>\n",
              "      <td>-2.7930</td>\n",
              "      <td>-2.1560</td>\n",
              "      <td>-2.4100</td>\n",
              "      <td>-1.8190</td>\n",
              "      <td>-3.3480</td>\n",
              "      <td>-0.1414</td>\n",
              "      <td>-2.6430</td>\n",
              "      <td>-2.5810</td>\n",
              "      <td>-3.3890</td>\n",
              "      <td>-1.7450</td>\n",
              "      <td>-6.6300</td>\n",
              "      <td>-4.0950</td>\n",
              "      <td>-7.3860</td>\n",
              "      <td>-1.4160</td>\n",
              "      <td>-3.5770</td>\n",
              "      <td>-0.4775</td>\n",
              "      <td>-2.1500</td>\n",
              "      <td>-4.2520</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>23814 rows × 877 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "                 id    tratamento  tempo dose  ...    c-96    c-97    c-98    c-99\n",
              "0      id_000644bb2     com_droga     24   D1  ... -0.3981  0.2139  0.3801  0.4176\n",
              "1      id_000779bfc     com_droga     72   D1  ...  0.1522  0.1241  0.6077  0.7371\n",
              "2      id_000a6266a     com_droga     48   D1  ... -0.6417 -0.2187 -1.4080  0.6931\n",
              "3      id_0015fd391     com_droga     48   D1  ... -1.6210 -0.8784 -0.3876 -0.8154\n",
              "4      id_001626bd3     com_droga     72   D2  ...  0.1094  0.2885 -0.3786  0.7125\n",
              "...             ...           ...    ...  ...  ...     ...     ...     ...     ...\n",
              "23809  id_fffb1ceed     com_droga     24   D2  ...  0.0631  0.9171  0.5258  0.4680\n",
              "23810  id_fffb70c0c     com_droga     24   D2  ... -0.2084 -0.1224 -0.2715  0.3689\n",
              "23811  id_fffc1c3f4  com_controle     48   D2  ...  0.2256  0.7592  0.6656  0.3808\n",
              "23812  id_fffcb9e7c     com_droga     24   D1  ...  0.1732  0.7015 -0.6290  0.0740\n",
              "23813  id_ffffdd77b     com_droga     72   D1  ... -3.5770 -0.4775 -2.1500 -4.2520\n",
              "\n",
              "[23814 rows x 877 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 2
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 269
        },
        "id": "ujJOdJ6T095r",
        "outputId": "4492f6c8-85d6-41fd-92dd-e6dde30e191e"
      },
      "source": [
        "dados_resultados = pd.read_csv('https://github.com/alura-cursos/imersaodados3/blob/main/dados/dados_resultados.csv?raw=true')\n",
        "dados_resultados.head()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>5-alpha_reductase_inhibitor</th>\n",
              "      <th>11-beta-hsd1_inhibitor</th>\n",
              "      <th>acat_inhibitor</th>\n",
              "      <th>acetylcholine_receptor_agonist</th>\n",
              "      <th>acetylcholine_receptor_antagonist</th>\n",
              "      <th>acetylcholinesterase_inhibitor</th>\n",
              "      <th>adenosine_receptor_agonist</th>\n",
              "      <th>adenosine_receptor_antagonist</th>\n",
              "      <th>adenylyl_cyclase_activator</th>\n",
              "      <th>adrenergic_receptor_agonist</th>\n",
              "      <th>adrenergic_receptor_antagonist</th>\n",
              "      <th>akt_inhibitor</th>\n",
              "      <th>aldehyde_dehydrogenase_inhibitor</th>\n",
              "      <th>alk_inhibitor</th>\n",
              "      <th>ampk_activator</th>\n",
              "      <th>analgesic</th>\n",
              "      <th>androgen_receptor_agonist</th>\n",
              "      <th>androgen_receptor_antagonist</th>\n",
              "      <th>anesthetic_-_local</th>\n",
              "      <th>angiogenesis_inhibitor</th>\n",
              "      <th>angiotensin_receptor_antagonist</th>\n",
              "      <th>anti-inflammatory</th>\n",
              "      <th>antiarrhythmic</th>\n",
              "      <th>antibiotic</th>\n",
              "      <th>anticonvulsant</th>\n",
              "      <th>antifungal</th>\n",
              "      <th>antihistamine</th>\n",
              "      <th>antimalarial</th>\n",
              "      <th>antioxidant</th>\n",
              "      <th>antiprotozoal</th>\n",
              "      <th>antiviral</th>\n",
              "      <th>apoptosis_stimulant</th>\n",
              "      <th>aromatase_inhibitor</th>\n",
              "      <th>atm_kinase_inhibitor</th>\n",
              "      <th>atp-sensitive_potassium_channel_antagonist</th>\n",
              "      <th>atp_synthase_inhibitor</th>\n",
              "      <th>atpase_inhibitor</th>\n",
              "      <th>atr_kinase_inhibitor</th>\n",
              "      <th>aurora_kinase_inhibitor</th>\n",
              "      <th>...</th>\n",
              "      <th>protein_synthesis_inhibitor</th>\n",
              "      <th>protein_tyrosine_kinase_inhibitor</th>\n",
              "      <th>radiopaque_medium</th>\n",
              "      <th>raf_inhibitor</th>\n",
              "      <th>ras_gtpase_inhibitor</th>\n",
              "      <th>retinoid_receptor_agonist</th>\n",
              "      <th>retinoid_receptor_antagonist</th>\n",
              "      <th>rho_associated_kinase_inhibitor</th>\n",
              "      <th>ribonucleoside_reductase_inhibitor</th>\n",
              "      <th>rna_polymerase_inhibitor</th>\n",
              "      <th>serotonin_receptor_agonist</th>\n",
              "      <th>serotonin_receptor_antagonist</th>\n",
              "      <th>serotonin_reuptake_inhibitor</th>\n",
              "      <th>sigma_receptor_agonist</th>\n",
              "      <th>sigma_receptor_antagonist</th>\n",
              "      <th>smoothened_receptor_antagonist</th>\n",
              "      <th>sodium_channel_inhibitor</th>\n",
              "      <th>sphingosine_receptor_agonist</th>\n",
              "      <th>src_inhibitor</th>\n",
              "      <th>steroid</th>\n",
              "      <th>syk_inhibitor</th>\n",
              "      <th>tachykinin_antagonist</th>\n",
              "      <th>tgf-beta_receptor_inhibitor</th>\n",
              "      <th>thrombin_inhibitor</th>\n",
              "      <th>thymidylate_synthase_inhibitor</th>\n",
              "      <th>tlr_agonist</th>\n",
              "      <th>tlr_antagonist</th>\n",
              "      <th>tnf_inhibitor</th>\n",
              "      <th>topoisomerase_inhibitor</th>\n",
              "      <th>transient_receptor_potential_channel_antagonist</th>\n",
              "      <th>tropomyosin_receptor_kinase_inhibitor</th>\n",
              "      <th>trpv_agonist</th>\n",
              "      <th>trpv_antagonist</th>\n",
              "      <th>tubulin_inhibitor</th>\n",
              "      <th>tyrosine_kinase_inhibitor</th>\n",
              "      <th>ubiquitin_specific_protease_inhibitor</th>\n",
              "      <th>vegfr_inhibitor</th>\n",
              "      <th>vitamin_b</th>\n",
              "      <th>vitamin_d_receptor_agonist</th>\n",
              "      <th>wnt_inhibitor</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>5 rows × 207 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "             id  ...  wnt_inhibitor\n",
              "0  id_000644bb2  ...              0\n",
              "1  id_000779bfc  ...              0\n",
              "2  id_000a6266a  ...              0\n",
              "3  id_0015fd391  ...              0\n",
              "4  id_001626bd3  ...              0\n",
              "\n",
              "[5 rows x 207 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 3
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "Jb3CPNkR2Cqz",
        "outputId": "04f9a5cf-d38e-4a58-90a2-128c4ecd2b3c"
      },
      "source": [
        "contagem_moa = dados_resultados.drop('id', axis=1).sum().sort_values(ascending=False)\n",
        "contagem_moa"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "nfkb_inhibitor                                832\n",
              "proteasome_inhibitor                          726\n",
              "cyclooxygenase_inhibitor                      435\n",
              "dopamine_receptor_antagonist                  424\n",
              "serotonin_receptor_antagonist                 404\n",
              "                                             ... \n",
              "protein_phosphatase_inhibitor                   6\n",
              "autotaxin_inhibitor                             6\n",
              "diuretic                                        6\n",
              "erbb2_inhibitor                                 1\n",
              "atp-sensitive_potassium_channel_antagonist      1\n",
              "Length: 206, dtype: int64"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 5
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "T1GX4pdy2EfC",
        "outputId": "8daafcc9-b94d-42e3-b210-fc84c000a420"
      },
      "source": [
        "dados_resultados.drop('id', axis=1).sum(axis=1)"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "0        1\n",
              "1        0\n",
              "2        3\n",
              "3        0\n",
              "4        1\n",
              "        ..\n",
              "23809    1\n",
              "23810    1\n",
              "23811    0\n",
              "23812    1\n",
              "23813    0\n",
              "Length: 23814, dtype: int64"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 6
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 269
        },
        "id": "Xn5j10fx2Epe",
        "outputId": "33ba50fd-e28f-4e57-db6b-7feac6ba4041"
      },
      "source": [
        "dados_resultados.head()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>5-alpha_reductase_inhibitor</th>\n",
              "      <th>11-beta-hsd1_inhibitor</th>\n",
              "      <th>acat_inhibitor</th>\n",
              "      <th>acetylcholine_receptor_agonist</th>\n",
              "      <th>acetylcholine_receptor_antagonist</th>\n",
              "      <th>acetylcholinesterase_inhibitor</th>\n",
              "      <th>adenosine_receptor_agonist</th>\n",
              "      <th>adenosine_receptor_antagonist</th>\n",
              "      <th>adenylyl_cyclase_activator</th>\n",
              "      <th>adrenergic_receptor_agonist</th>\n",
              "      <th>adrenergic_receptor_antagonist</th>\n",
              "      <th>akt_inhibitor</th>\n",
              "      <th>aldehyde_dehydrogenase_inhibitor</th>\n",
              "      <th>alk_inhibitor</th>\n",
              "      <th>ampk_activator</th>\n",
              "      <th>analgesic</th>\n",
              "      <th>androgen_receptor_agonist</th>\n",
              "      <th>androgen_receptor_antagonist</th>\n",
              "      <th>anesthetic_-_local</th>\n",
              "      <th>angiogenesis_inhibitor</th>\n",
              "      <th>angiotensin_receptor_antagonist</th>\n",
              "      <th>anti-inflammatory</th>\n",
              "      <th>antiarrhythmic</th>\n",
              "      <th>antibiotic</th>\n",
              "      <th>anticonvulsant</th>\n",
              "      <th>antifungal</th>\n",
              "      <th>antihistamine</th>\n",
              "      <th>antimalarial</th>\n",
              "      <th>antioxidant</th>\n",
              "      <th>antiprotozoal</th>\n",
              "      <th>antiviral</th>\n",
              "      <th>apoptosis_stimulant</th>\n",
              "      <th>aromatase_inhibitor</th>\n",
              "      <th>atm_kinase_inhibitor</th>\n",
              "      <th>atp-sensitive_potassium_channel_antagonist</th>\n",
              "      <th>atp_synthase_inhibitor</th>\n",
              "      <th>atpase_inhibitor</th>\n",
              "      <th>atr_kinase_inhibitor</th>\n",
              "      <th>aurora_kinase_inhibitor</th>\n",
              "      <th>...</th>\n",
              "      <th>protein_synthesis_inhibitor</th>\n",
              "      <th>protein_tyrosine_kinase_inhibitor</th>\n",
              "      <th>radiopaque_medium</th>\n",
              "      <th>raf_inhibitor</th>\n",
              "      <th>ras_gtpase_inhibitor</th>\n",
              "      <th>retinoid_receptor_agonist</th>\n",
              "      <th>retinoid_receptor_antagonist</th>\n",
              "      <th>rho_associated_kinase_inhibitor</th>\n",
              "      <th>ribonucleoside_reductase_inhibitor</th>\n",
              "      <th>rna_polymerase_inhibitor</th>\n",
              "      <th>serotonin_receptor_agonist</th>\n",
              "      <th>serotonin_receptor_antagonist</th>\n",
              "      <th>serotonin_reuptake_inhibitor</th>\n",
              "      <th>sigma_receptor_agonist</th>\n",
              "      <th>sigma_receptor_antagonist</th>\n",
              "      <th>smoothened_receptor_antagonist</th>\n",
              "      <th>sodium_channel_inhibitor</th>\n",
              "      <th>sphingosine_receptor_agonist</th>\n",
              "      <th>src_inhibitor</th>\n",
              "      <th>steroid</th>\n",
              "      <th>syk_inhibitor</th>\n",
              "      <th>tachykinin_antagonist</th>\n",
              "      <th>tgf-beta_receptor_inhibitor</th>\n",
              "      <th>thrombin_inhibitor</th>\n",
              "      <th>thymidylate_synthase_inhibitor</th>\n",
              "      <th>tlr_agonist</th>\n",
              "      <th>tlr_antagonist</th>\n",
              "      <th>tnf_inhibitor</th>\n",
              "      <th>topoisomerase_inhibitor</th>\n",
              "      <th>transient_receptor_potential_channel_antagonist</th>\n",
              "      <th>tropomyosin_receptor_kinase_inhibitor</th>\n",
              "      <th>trpv_agonist</th>\n",
              "      <th>trpv_antagonist</th>\n",
              "      <th>tubulin_inhibitor</th>\n",
              "      <th>tyrosine_kinase_inhibitor</th>\n",
              "      <th>ubiquitin_specific_protease_inhibitor</th>\n",
              "      <th>vegfr_inhibitor</th>\n",
              "      <th>vitamin_b</th>\n",
              "      <th>vitamin_d_receptor_agonist</th>\n",
              "      <th>wnt_inhibitor</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>5 rows × 207 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "             id  ...  wnt_inhibitor\n",
              "0  id_000644bb2  ...              0\n",
              "1  id_000779bfc  ...              0\n",
              "2  id_000a6266a  ...              0\n",
              "3  id_0015fd391  ...              0\n",
              "4  id_001626bd3  ...              0\n",
              "\n",
              "[5 rows x 207 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 7
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 251
        },
        "id": "1bFzPMOm2EvS",
        "outputId": "2324d112-73b7-4ed4-8f0b-2206277e003e"
      },
      "source": [
        "dados.head()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>tratamento</th>\n",
              "      <th>tempo</th>\n",
              "      <th>dose</th>\n",
              "      <th>composto</th>\n",
              "      <th>g-0</th>\n",
              "      <th>g-1</th>\n",
              "      <th>g-2</th>\n",
              "      <th>g-3</th>\n",
              "      <th>g-4</th>\n",
              "      <th>g-5</th>\n",
              "      <th>g-6</th>\n",
              "      <th>g-7</th>\n",
              "      <th>g-8</th>\n",
              "      <th>g-9</th>\n",
              "      <th>g-10</th>\n",
              "      <th>g-11</th>\n",
              "      <th>g-12</th>\n",
              "      <th>g-13</th>\n",
              "      <th>g-14</th>\n",
              "      <th>g-15</th>\n",
              "      <th>g-16</th>\n",
              "      <th>g-17</th>\n",
              "      <th>g-18</th>\n",
              "      <th>g-19</th>\n",
              "      <th>g-20</th>\n",
              "      <th>g-21</th>\n",
              "      <th>g-22</th>\n",
              "      <th>g-23</th>\n",
              "      <th>g-24</th>\n",
              "      <th>g-25</th>\n",
              "      <th>g-26</th>\n",
              "      <th>g-27</th>\n",
              "      <th>g-28</th>\n",
              "      <th>g-29</th>\n",
              "      <th>g-30</th>\n",
              "      <th>g-31</th>\n",
              "      <th>g-32</th>\n",
              "      <th>g-33</th>\n",
              "      <th>g-34</th>\n",
              "      <th>...</th>\n",
              "      <th>c-60</th>\n",
              "      <th>c-61</th>\n",
              "      <th>c-62</th>\n",
              "      <th>c-63</th>\n",
              "      <th>c-64</th>\n",
              "      <th>c-65</th>\n",
              "      <th>c-66</th>\n",
              "      <th>c-67</th>\n",
              "      <th>c-68</th>\n",
              "      <th>c-69</th>\n",
              "      <th>c-70</th>\n",
              "      <th>c-71</th>\n",
              "      <th>c-72</th>\n",
              "      <th>c-73</th>\n",
              "      <th>c-74</th>\n",
              "      <th>c-75</th>\n",
              "      <th>c-76</th>\n",
              "      <th>c-77</th>\n",
              "      <th>c-78</th>\n",
              "      <th>c-79</th>\n",
              "      <th>c-80</th>\n",
              "      <th>c-81</th>\n",
              "      <th>c-82</th>\n",
              "      <th>c-83</th>\n",
              "      <th>c-84</th>\n",
              "      <th>c-85</th>\n",
              "      <th>c-86</th>\n",
              "      <th>c-87</th>\n",
              "      <th>c-88</th>\n",
              "      <th>c-89</th>\n",
              "      <th>c-90</th>\n",
              "      <th>c-91</th>\n",
              "      <th>c-92</th>\n",
              "      <th>c-93</th>\n",
              "      <th>c-94</th>\n",
              "      <th>c-95</th>\n",
              "      <th>c-96</th>\n",
              "      <th>c-97</th>\n",
              "      <th>c-98</th>\n",
              "      <th>c-99</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D1</td>\n",
              "      <td>b68db1d53</td>\n",
              "      <td>1.0620</td>\n",
              "      <td>0.5577</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-0.6208</td>\n",
              "      <td>-0.1944</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>-1.0220</td>\n",
              "      <td>-0.0326</td>\n",
              "      <td>0.5548</td>\n",
              "      <td>-0.0921</td>\n",
              "      <td>1.1830</td>\n",
              "      <td>0.1530</td>\n",
              "      <td>0.5574</td>\n",
              "      <td>-0.4015</td>\n",
              "      <td>0.1789</td>\n",
              "      <td>-0.6528</td>\n",
              "      <td>-0.7969</td>\n",
              "      <td>0.6342</td>\n",
              "      <td>0.1778</td>\n",
              "      <td>-0.3694</td>\n",
              "      <td>-0.5688</td>\n",
              "      <td>-1.1360</td>\n",
              "      <td>-1.1880</td>\n",
              "      <td>0.6940</td>\n",
              "      <td>0.4393</td>\n",
              "      <td>0.2664</td>\n",
              "      <td>0.1907</td>\n",
              "      <td>0.1628</td>\n",
              "      <td>-0.2853</td>\n",
              "      <td>0.5819</td>\n",
              "      <td>0.2934</td>\n",
              "      <td>-0.5584</td>\n",
              "      <td>-0.0916</td>\n",
              "      <td>-0.3010</td>\n",
              "      <td>-0.1537</td>\n",
              "      <td>...</td>\n",
              "      <td>0.4805</td>\n",
              "      <td>0.4965</td>\n",
              "      <td>0.3680</td>\n",
              "      <td>0.8427</td>\n",
              "      <td>0.1042</td>\n",
              "      <td>0.1403</td>\n",
              "      <td>0.1758</td>\n",
              "      <td>1.2570</td>\n",
              "      <td>-0.5979</td>\n",
              "      <td>1.2250</td>\n",
              "      <td>-0.0553</td>\n",
              "      <td>0.7351</td>\n",
              "      <td>0.5810</td>\n",
              "      <td>0.9590</td>\n",
              "      <td>0.2427</td>\n",
              "      <td>0.0495</td>\n",
              "      <td>0.4141</td>\n",
              "      <td>0.8432</td>\n",
              "      <td>0.6162</td>\n",
              "      <td>-0.7318</td>\n",
              "      <td>1.2120</td>\n",
              "      <td>0.6362</td>\n",
              "      <td>-0.4427</td>\n",
              "      <td>0.1288</td>\n",
              "      <td>1.4840</td>\n",
              "      <td>0.1799</td>\n",
              "      <td>0.5367</td>\n",
              "      <td>-0.1111</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>0.6685</td>\n",
              "      <td>0.2862</td>\n",
              "      <td>0.2584</td>\n",
              "      <td>0.8076</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.1912</td>\n",
              "      <td>0.6584</td>\n",
              "      <td>-0.3981</td>\n",
              "      <td>0.2139</td>\n",
              "      <td>0.3801</td>\n",
              "      <td>0.4176</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D1</td>\n",
              "      <td>df89a8e5a</td>\n",
              "      <td>0.0743</td>\n",
              "      <td>0.4087</td>\n",
              "      <td>0.2991</td>\n",
              "      <td>0.0604</td>\n",
              "      <td>1.0190</td>\n",
              "      <td>0.5207</td>\n",
              "      <td>0.2341</td>\n",
              "      <td>0.3372</td>\n",
              "      <td>-0.4047</td>\n",
              "      <td>0.8507</td>\n",
              "      <td>-1.1520</td>\n",
              "      <td>-0.4201</td>\n",
              "      <td>-0.0958</td>\n",
              "      <td>0.4590</td>\n",
              "      <td>0.0803</td>\n",
              "      <td>0.2250</td>\n",
              "      <td>0.5293</td>\n",
              "      <td>0.2839</td>\n",
              "      <td>-0.3494</td>\n",
              "      <td>0.2883</td>\n",
              "      <td>0.9449</td>\n",
              "      <td>-0.1646</td>\n",
              "      <td>-0.2657</td>\n",
              "      <td>-0.3372</td>\n",
              "      <td>0.3135</td>\n",
              "      <td>-0.4316</td>\n",
              "      <td>0.4773</td>\n",
              "      <td>0.2075</td>\n",
              "      <td>-0.4216</td>\n",
              "      <td>-0.1161</td>\n",
              "      <td>-0.0499</td>\n",
              "      <td>-0.2627</td>\n",
              "      <td>0.9959</td>\n",
              "      <td>-0.2483</td>\n",
              "      <td>0.2655</td>\n",
              "      <td>...</td>\n",
              "      <td>0.4083</td>\n",
              "      <td>0.0319</td>\n",
              "      <td>0.3905</td>\n",
              "      <td>0.7099</td>\n",
              "      <td>0.2912</td>\n",
              "      <td>0.4151</td>\n",
              "      <td>-0.2840</td>\n",
              "      <td>-0.3104</td>\n",
              "      <td>-0.6373</td>\n",
              "      <td>0.2887</td>\n",
              "      <td>-0.0765</td>\n",
              "      <td>0.2539</td>\n",
              "      <td>0.4443</td>\n",
              "      <td>0.5932</td>\n",
              "      <td>0.2031</td>\n",
              "      <td>0.7639</td>\n",
              "      <td>0.5499</td>\n",
              "      <td>-0.3322</td>\n",
              "      <td>-0.0977</td>\n",
              "      <td>0.4329</td>\n",
              "      <td>-0.2782</td>\n",
              "      <td>0.7827</td>\n",
              "      <td>0.5934</td>\n",
              "      <td>0.3402</td>\n",
              "      <td>0.1499</td>\n",
              "      <td>0.4420</td>\n",
              "      <td>0.9366</td>\n",
              "      <td>0.8193</td>\n",
              "      <td>-0.4236</td>\n",
              "      <td>0.3192</td>\n",
              "      <td>-0.4265</td>\n",
              "      <td>0.7543</td>\n",
              "      <td>0.4708</td>\n",
              "      <td>0.0230</td>\n",
              "      <td>0.2957</td>\n",
              "      <td>0.4899</td>\n",
              "      <td>0.1522</td>\n",
              "      <td>0.1241</td>\n",
              "      <td>0.6077</td>\n",
              "      <td>0.7371</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>48</td>\n",
              "      <td>D1</td>\n",
              "      <td>18bb41b2c</td>\n",
              "      <td>0.6280</td>\n",
              "      <td>0.5817</td>\n",
              "      <td>1.5540</td>\n",
              "      <td>-0.0764</td>\n",
              "      <td>-0.0323</td>\n",
              "      <td>1.2390</td>\n",
              "      <td>0.1715</td>\n",
              "      <td>0.2155</td>\n",
              "      <td>0.0065</td>\n",
              "      <td>1.2300</td>\n",
              "      <td>-0.4797</td>\n",
              "      <td>-0.5631</td>\n",
              "      <td>-0.0366</td>\n",
              "      <td>-1.8300</td>\n",
              "      <td>0.6057</td>\n",
              "      <td>-0.3278</td>\n",
              "      <td>0.6042</td>\n",
              "      <td>-0.3075</td>\n",
              "      <td>-0.1147</td>\n",
              "      <td>-0.0570</td>\n",
              "      <td>-0.0799</td>\n",
              "      <td>-0.8181</td>\n",
              "      <td>-1.5320</td>\n",
              "      <td>0.2307</td>\n",
              "      <td>0.4901</td>\n",
              "      <td>0.4780</td>\n",
              "      <td>-1.3970</td>\n",
              "      <td>4.6240</td>\n",
              "      <td>-0.0437</td>\n",
              "      <td>1.2870</td>\n",
              "      <td>-1.8530</td>\n",
              "      <td>0.6069</td>\n",
              "      <td>0.4290</td>\n",
              "      <td>0.1783</td>\n",
              "      <td>0.0018</td>\n",
              "      <td>...</td>\n",
              "      <td>-0.5477</td>\n",
              "      <td>-0.7576</td>\n",
              "      <td>-0.0444</td>\n",
              "      <td>0.1894</td>\n",
              "      <td>-0.0014</td>\n",
              "      <td>-2.3640</td>\n",
              "      <td>-0.4682</td>\n",
              "      <td>0.1210</td>\n",
              "      <td>-0.5177</td>\n",
              "      <td>-0.0604</td>\n",
              "      <td>0.1682</td>\n",
              "      <td>-0.4436</td>\n",
              "      <td>0.4963</td>\n",
              "      <td>0.1363</td>\n",
              "      <td>0.3335</td>\n",
              "      <td>0.9760</td>\n",
              "      <td>-0.0427</td>\n",
              "      <td>-0.1235</td>\n",
              "      <td>0.0959</td>\n",
              "      <td>0.0690</td>\n",
              "      <td>-0.9416</td>\n",
              "      <td>-0.7548</td>\n",
              "      <td>-0.1109</td>\n",
              "      <td>-0.6272</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>0.1172</td>\n",
              "      <td>0.1093</td>\n",
              "      <td>-0.3113</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>-0.0873</td>\n",
              "      <td>-0.7250</td>\n",
              "      <td>-0.6297</td>\n",
              "      <td>0.6103</td>\n",
              "      <td>0.0223</td>\n",
              "      <td>-1.3240</td>\n",
              "      <td>-0.3174</td>\n",
              "      <td>-0.6417</td>\n",
              "      <td>-0.2187</td>\n",
              "      <td>-1.4080</td>\n",
              "      <td>0.6931</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>48</td>\n",
              "      <td>D1</td>\n",
              "      <td>8c7f86626</td>\n",
              "      <td>-0.5138</td>\n",
              "      <td>-0.2491</td>\n",
              "      <td>-0.2656</td>\n",
              "      <td>0.5288</td>\n",
              "      <td>4.0620</td>\n",
              "      <td>-0.8095</td>\n",
              "      <td>-1.9590</td>\n",
              "      <td>0.1792</td>\n",
              "      <td>-0.1321</td>\n",
              "      <td>-1.0600</td>\n",
              "      <td>-0.8269</td>\n",
              "      <td>-0.3584</td>\n",
              "      <td>-0.8511</td>\n",
              "      <td>-0.5844</td>\n",
              "      <td>-2.5690</td>\n",
              "      <td>0.8183</td>\n",
              "      <td>-0.0532</td>\n",
              "      <td>-0.8554</td>\n",
              "      <td>0.1160</td>\n",
              "      <td>-2.3520</td>\n",
              "      <td>2.1200</td>\n",
              "      <td>-1.1580</td>\n",
              "      <td>-0.7191</td>\n",
              "      <td>-0.8004</td>\n",
              "      <td>-1.4670</td>\n",
              "      <td>-0.0107</td>\n",
              "      <td>-0.8995</td>\n",
              "      <td>0.2406</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-1.0890</td>\n",
              "      <td>-0.7575</td>\n",
              "      <td>0.0881</td>\n",
              "      <td>-2.7370</td>\n",
              "      <td>0.8745</td>\n",
              "      <td>0.5787</td>\n",
              "      <td>...</td>\n",
              "      <td>-2.1220</td>\n",
              "      <td>-0.3752</td>\n",
              "      <td>-2.3820</td>\n",
              "      <td>-3.7350</td>\n",
              "      <td>-2.9740</td>\n",
              "      <td>-1.4930</td>\n",
              "      <td>-1.6600</td>\n",
              "      <td>-3.1660</td>\n",
              "      <td>0.2816</td>\n",
              "      <td>-0.2990</td>\n",
              "      <td>-1.1870</td>\n",
              "      <td>-0.5044</td>\n",
              "      <td>-1.7750</td>\n",
              "      <td>-1.6120</td>\n",
              "      <td>-0.9215</td>\n",
              "      <td>-1.0810</td>\n",
              "      <td>-3.0520</td>\n",
              "      <td>-3.4470</td>\n",
              "      <td>-2.7740</td>\n",
              "      <td>-1.8460</td>\n",
              "      <td>-0.5568</td>\n",
              "      <td>-3.3960</td>\n",
              "      <td>-2.9510</td>\n",
              "      <td>-1.1550</td>\n",
              "      <td>-3.2620</td>\n",
              "      <td>-1.5390</td>\n",
              "      <td>-2.4600</td>\n",
              "      <td>-0.9417</td>\n",
              "      <td>-1.5550</td>\n",
              "      <td>0.2431</td>\n",
              "      <td>-2.0990</td>\n",
              "      <td>-0.6441</td>\n",
              "      <td>-5.6300</td>\n",
              "      <td>-1.3780</td>\n",
              "      <td>-0.8632</td>\n",
              "      <td>-1.2880</td>\n",
              "      <td>-1.6210</td>\n",
              "      <td>-0.8784</td>\n",
              "      <td>-0.3876</td>\n",
              "      <td>-0.8154</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D2</td>\n",
              "      <td>7cbed3131</td>\n",
              "      <td>-0.3254</td>\n",
              "      <td>-0.4009</td>\n",
              "      <td>0.9700</td>\n",
              "      <td>0.6919</td>\n",
              "      <td>1.4180</td>\n",
              "      <td>-0.8244</td>\n",
              "      <td>-0.2800</td>\n",
              "      <td>-0.1498</td>\n",
              "      <td>-0.8789</td>\n",
              "      <td>0.8630</td>\n",
              "      <td>-0.2219</td>\n",
              "      <td>-0.5121</td>\n",
              "      <td>-0.9577</td>\n",
              "      <td>1.1750</td>\n",
              "      <td>0.2042</td>\n",
              "      <td>0.1970</td>\n",
              "      <td>0.1244</td>\n",
              "      <td>-1.7090</td>\n",
              "      <td>-0.3543</td>\n",
              "      <td>-0.5160</td>\n",
              "      <td>-0.3330</td>\n",
              "      <td>-0.2685</td>\n",
              "      <td>0.7649</td>\n",
              "      <td>0.2057</td>\n",
              "      <td>1.3720</td>\n",
              "      <td>0.6835</td>\n",
              "      <td>0.8056</td>\n",
              "      <td>-0.3754</td>\n",
              "      <td>-1.2090</td>\n",
              "      <td>0.2965</td>\n",
              "      <td>-0.0712</td>\n",
              "      <td>0.6389</td>\n",
              "      <td>0.6674</td>\n",
              "      <td>-0.0783</td>\n",
              "      <td>1.1740</td>\n",
              "      <td>...</td>\n",
              "      <td>-0.2274</td>\n",
              "      <td>0.3215</td>\n",
              "      <td>0.1535</td>\n",
              "      <td>-0.4640</td>\n",
              "      <td>-0.5943</td>\n",
              "      <td>0.3973</td>\n",
              "      <td>0.1500</td>\n",
              "      <td>0.5178</td>\n",
              "      <td>0.5159</td>\n",
              "      <td>0.6091</td>\n",
              "      <td>0.1813</td>\n",
              "      <td>-0.4249</td>\n",
              "      <td>0.7832</td>\n",
              "      <td>0.6529</td>\n",
              "      <td>0.5648</td>\n",
              "      <td>0.4817</td>\n",
              "      <td>0.0587</td>\n",
              "      <td>0.5303</td>\n",
              "      <td>0.6376</td>\n",
              "      <td>-0.3966</td>\n",
              "      <td>-1.4950</td>\n",
              "      <td>-0.9625</td>\n",
              "      <td>-0.0541</td>\n",
              "      <td>0.6273</td>\n",
              "      <td>0.4563</td>\n",
              "      <td>0.0698</td>\n",
              "      <td>0.8134</td>\n",
              "      <td>0.1924</td>\n",
              "      <td>0.6054</td>\n",
              "      <td>-0.1824</td>\n",
              "      <td>0.0042</td>\n",
              "      <td>0.0048</td>\n",
              "      <td>0.6670</td>\n",
              "      <td>1.0690</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.3031</td>\n",
              "      <td>0.1094</td>\n",
              "      <td>0.2885</td>\n",
              "      <td>-0.3786</td>\n",
              "      <td>0.7125</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>5 rows × 877 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "             id tratamento  tempo dose  ...    c-96    c-97    c-98    c-99\n",
              "0  id_000644bb2  com_droga     24   D1  ... -0.3981  0.2139  0.3801  0.4176\n",
              "1  id_000779bfc  com_droga     72   D1  ...  0.1522  0.1241  0.6077  0.7371\n",
              "2  id_000a6266a  com_droga     48   D1  ... -0.6417 -0.2187 -1.4080  0.6931\n",
              "3  id_0015fd391  com_droga     48   D1  ... -1.6210 -0.8784 -0.3876 -0.8154\n",
              "4  id_001626bd3  com_droga     72   D2  ...  0.1094  0.2885 -0.3786  0.7125\n",
              "\n",
              "[5 rows x 877 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 8
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "id": "TBuNiMXy2OlE"
      },
      "source": [
        "dados_resultados['n_moa'] = dados_resultados.drop('id', axis=1).sum(axis=1)"
      ],
      "execution_count": null,
      "outputs": []
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "lsmH7SpZ2Oor",
        "outputId": "e6892358-6cea-47b2-a6a3-b84768e032f3"
      },
      "source": [
        "dados_resultados['n_moa'] != 0"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "0         True\n",
              "1        False\n",
              "2         True\n",
              "3        False\n",
              "4         True\n",
              "         ...  \n",
              "23809     True\n",
              "23810     True\n",
              "23811    False\n",
              "23812     True\n",
              "23813    False\n",
              "Name: n_moa, Length: 23814, dtype: bool"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 10
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 269
        },
        "id": "1LIFXbLA2VpO",
        "outputId": "9ed8eb41-d6cd-4c93-f484-cccc38b12daf"
      },
      "source": [
        "dados_resultados['ativo_moa'] = (dados_resultados['n_moa'] != 0)\n",
        "dados_resultados.head()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>5-alpha_reductase_inhibitor</th>\n",
              "      <th>11-beta-hsd1_inhibitor</th>\n",
              "      <th>acat_inhibitor</th>\n",
              "      <th>acetylcholine_receptor_agonist</th>\n",
              "      <th>acetylcholine_receptor_antagonist</th>\n",
              "      <th>acetylcholinesterase_inhibitor</th>\n",
              "      <th>adenosine_receptor_agonist</th>\n",
              "      <th>adenosine_receptor_antagonist</th>\n",
              "      <th>adenylyl_cyclase_activator</th>\n",
              "      <th>adrenergic_receptor_agonist</th>\n",
              "      <th>adrenergic_receptor_antagonist</th>\n",
              "      <th>akt_inhibitor</th>\n",
              "      <th>aldehyde_dehydrogenase_inhibitor</th>\n",
              "      <th>alk_inhibitor</th>\n",
              "      <th>ampk_activator</th>\n",
              "      <th>analgesic</th>\n",
              "      <th>androgen_receptor_agonist</th>\n",
              "      <th>androgen_receptor_antagonist</th>\n",
              "      <th>anesthetic_-_local</th>\n",
              "      <th>angiogenesis_inhibitor</th>\n",
              "      <th>angiotensin_receptor_antagonist</th>\n",
              "      <th>anti-inflammatory</th>\n",
              "      <th>antiarrhythmic</th>\n",
              "      <th>antibiotic</th>\n",
              "      <th>anticonvulsant</th>\n",
              "      <th>antifungal</th>\n",
              "      <th>antihistamine</th>\n",
              "      <th>antimalarial</th>\n",
              "      <th>antioxidant</th>\n",
              "      <th>antiprotozoal</th>\n",
              "      <th>antiviral</th>\n",
              "      <th>apoptosis_stimulant</th>\n",
              "      <th>aromatase_inhibitor</th>\n",
              "      <th>atm_kinase_inhibitor</th>\n",
              "      <th>atp-sensitive_potassium_channel_antagonist</th>\n",
              "      <th>atp_synthase_inhibitor</th>\n",
              "      <th>atpase_inhibitor</th>\n",
              "      <th>atr_kinase_inhibitor</th>\n",
              "      <th>aurora_kinase_inhibitor</th>\n",
              "      <th>...</th>\n",
              "      <th>radiopaque_medium</th>\n",
              "      <th>raf_inhibitor</th>\n",
              "      <th>ras_gtpase_inhibitor</th>\n",
              "      <th>retinoid_receptor_agonist</th>\n",
              "      <th>retinoid_receptor_antagonist</th>\n",
              "      <th>rho_associated_kinase_inhibitor</th>\n",
              "      <th>ribonucleoside_reductase_inhibitor</th>\n",
              "      <th>rna_polymerase_inhibitor</th>\n",
              "      <th>serotonin_receptor_agonist</th>\n",
              "      <th>serotonin_receptor_antagonist</th>\n",
              "      <th>serotonin_reuptake_inhibitor</th>\n",
              "      <th>sigma_receptor_agonist</th>\n",
              "      <th>sigma_receptor_antagonist</th>\n",
              "      <th>smoothened_receptor_antagonist</th>\n",
              "      <th>sodium_channel_inhibitor</th>\n",
              "      <th>sphingosine_receptor_agonist</th>\n",
              "      <th>src_inhibitor</th>\n",
              "      <th>steroid</th>\n",
              "      <th>syk_inhibitor</th>\n",
              "      <th>tachykinin_antagonist</th>\n",
              "      <th>tgf-beta_receptor_inhibitor</th>\n",
              "      <th>thrombin_inhibitor</th>\n",
              "      <th>thymidylate_synthase_inhibitor</th>\n",
              "      <th>tlr_agonist</th>\n",
              "      <th>tlr_antagonist</th>\n",
              "      <th>tnf_inhibitor</th>\n",
              "      <th>topoisomerase_inhibitor</th>\n",
              "      <th>transient_receptor_potential_channel_antagonist</th>\n",
              "      <th>tropomyosin_receptor_kinase_inhibitor</th>\n",
              "      <th>trpv_agonist</th>\n",
              "      <th>trpv_antagonist</th>\n",
              "      <th>tubulin_inhibitor</th>\n",
              "      <th>tyrosine_kinase_inhibitor</th>\n",
              "      <th>ubiquitin_specific_protease_inhibitor</th>\n",
              "      <th>vegfr_inhibitor</th>\n",
              "      <th>vitamin_b</th>\n",
              "      <th>vitamin_d_receptor_agonist</th>\n",
              "      <th>wnt_inhibitor</th>\n",
              "      <th>n_moa</th>\n",
              "      <th>ativo_moa</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "      <td>True</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>3</td>\n",
              "      <td>True</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "      <td>True</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>5 rows × 209 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "             id  5-alpha_reductase_inhibitor  ...  n_moa  ativo_moa\n",
              "0  id_000644bb2                            0  ...      1       True\n",
              "1  id_000779bfc                            0  ...      0      False\n",
              "2  id_000a6266a                            0  ...      3       True\n",
              "3  id_0015fd391                            0  ...      0      False\n",
              "4  id_001626bd3                            0  ...      1       True\n",
              "\n",
              "[5 rows x 209 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 11
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 251
        },
        "id": "AZtQvXrT2V50",
        "outputId": "3b3a2d15-1a6a-4516-9610-e6013a6e7658"
      },
      "source": [
        " dados_combinados = pd.merge(dados, dados_resultados[['id','n_moa', 'ativo_moa']], on='id')\n",
        " dados_combinados.head()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>tratamento</th>\n",
              "      <th>tempo</th>\n",
              "      <th>dose</th>\n",
              "      <th>composto</th>\n",
              "      <th>g-0</th>\n",
              "      <th>g-1</th>\n",
              "      <th>g-2</th>\n",
              "      <th>g-3</th>\n",
              "      <th>g-4</th>\n",
              "      <th>g-5</th>\n",
              "      <th>g-6</th>\n",
              "      <th>g-7</th>\n",
              "      <th>g-8</th>\n",
              "      <th>g-9</th>\n",
              "      <th>g-10</th>\n",
              "      <th>g-11</th>\n",
              "      <th>g-12</th>\n",
              "      <th>g-13</th>\n",
              "      <th>g-14</th>\n",
              "      <th>g-15</th>\n",
              "      <th>g-16</th>\n",
              "      <th>g-17</th>\n",
              "      <th>g-18</th>\n",
              "      <th>g-19</th>\n",
              "      <th>g-20</th>\n",
              "      <th>g-21</th>\n",
              "      <th>g-22</th>\n",
              "      <th>g-23</th>\n",
              "      <th>g-24</th>\n",
              "      <th>g-25</th>\n",
              "      <th>g-26</th>\n",
              "      <th>g-27</th>\n",
              "      <th>g-28</th>\n",
              "      <th>g-29</th>\n",
              "      <th>g-30</th>\n",
              "      <th>g-31</th>\n",
              "      <th>g-32</th>\n",
              "      <th>g-33</th>\n",
              "      <th>g-34</th>\n",
              "      <th>...</th>\n",
              "      <th>c-62</th>\n",
              "      <th>c-63</th>\n",
              "      <th>c-64</th>\n",
              "      <th>c-65</th>\n",
              "      <th>c-66</th>\n",
              "      <th>c-67</th>\n",
              "      <th>c-68</th>\n",
              "      <th>c-69</th>\n",
              "      <th>c-70</th>\n",
              "      <th>c-71</th>\n",
              "      <th>c-72</th>\n",
              "      <th>c-73</th>\n",
              "      <th>c-74</th>\n",
              "      <th>c-75</th>\n",
              "      <th>c-76</th>\n",
              "      <th>c-77</th>\n",
              "      <th>c-78</th>\n",
              "      <th>c-79</th>\n",
              "      <th>c-80</th>\n",
              "      <th>c-81</th>\n",
              "      <th>c-82</th>\n",
              "      <th>c-83</th>\n",
              "      <th>c-84</th>\n",
              "      <th>c-85</th>\n",
              "      <th>c-86</th>\n",
              "      <th>c-87</th>\n",
              "      <th>c-88</th>\n",
              "      <th>c-89</th>\n",
              "      <th>c-90</th>\n",
              "      <th>c-91</th>\n",
              "      <th>c-92</th>\n",
              "      <th>c-93</th>\n",
              "      <th>c-94</th>\n",
              "      <th>c-95</th>\n",
              "      <th>c-96</th>\n",
              "      <th>c-97</th>\n",
              "      <th>c-98</th>\n",
              "      <th>c-99</th>\n",
              "      <th>n_moa</th>\n",
              "      <th>ativo_moa</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D1</td>\n",
              "      <td>b68db1d53</td>\n",
              "      <td>1.0620</td>\n",
              "      <td>0.5577</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-0.6208</td>\n",
              "      <td>-0.1944</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>-1.0220</td>\n",
              "      <td>-0.0326</td>\n",
              "      <td>0.5548</td>\n",
              "      <td>-0.0921</td>\n",
              "      <td>1.1830</td>\n",
              "      <td>0.1530</td>\n",
              "      <td>0.5574</td>\n",
              "      <td>-0.4015</td>\n",
              "      <td>0.1789</td>\n",
              "      <td>-0.6528</td>\n",
              "      <td>-0.7969</td>\n",
              "      <td>0.6342</td>\n",
              "      <td>0.1778</td>\n",
              "      <td>-0.3694</td>\n",
              "      <td>-0.5688</td>\n",
              "      <td>-1.1360</td>\n",
              "      <td>-1.1880</td>\n",
              "      <td>0.6940</td>\n",
              "      <td>0.4393</td>\n",
              "      <td>0.2664</td>\n",
              "      <td>0.1907</td>\n",
              "      <td>0.1628</td>\n",
              "      <td>-0.2853</td>\n",
              "      <td>0.5819</td>\n",
              "      <td>0.2934</td>\n",
              "      <td>-0.5584</td>\n",
              "      <td>-0.0916</td>\n",
              "      <td>-0.3010</td>\n",
              "      <td>-0.1537</td>\n",
              "      <td>...</td>\n",
              "      <td>0.3680</td>\n",
              "      <td>0.8427</td>\n",
              "      <td>0.1042</td>\n",
              "      <td>0.1403</td>\n",
              "      <td>0.1758</td>\n",
              "      <td>1.2570</td>\n",
              "      <td>-0.5979</td>\n",
              "      <td>1.2250</td>\n",
              "      <td>-0.0553</td>\n",
              "      <td>0.7351</td>\n",
              "      <td>0.5810</td>\n",
              "      <td>0.9590</td>\n",
              "      <td>0.2427</td>\n",
              "      <td>0.0495</td>\n",
              "      <td>0.4141</td>\n",
              "      <td>0.8432</td>\n",
              "      <td>0.6162</td>\n",
              "      <td>-0.7318</td>\n",
              "      <td>1.2120</td>\n",
              "      <td>0.6362</td>\n",
              "      <td>-0.4427</td>\n",
              "      <td>0.1288</td>\n",
              "      <td>1.4840</td>\n",
              "      <td>0.1799</td>\n",
              "      <td>0.5367</td>\n",
              "      <td>-0.1111</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>0.6685</td>\n",
              "      <td>0.2862</td>\n",
              "      <td>0.2584</td>\n",
              "      <td>0.8076</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.1912</td>\n",
              "      <td>0.6584</td>\n",
              "      <td>-0.3981</td>\n",
              "      <td>0.2139</td>\n",
              "      <td>0.3801</td>\n",
              "      <td>0.4176</td>\n",
              "      <td>1</td>\n",
              "      <td>True</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D1</td>\n",
              "      <td>df89a8e5a</td>\n",
              "      <td>0.0743</td>\n",
              "      <td>0.4087</td>\n",
              "      <td>0.2991</td>\n",
              "      <td>0.0604</td>\n",
              "      <td>1.0190</td>\n",
              "      <td>0.5207</td>\n",
              "      <td>0.2341</td>\n",
              "      <td>0.3372</td>\n",
              "      <td>-0.4047</td>\n",
              "      <td>0.8507</td>\n",
              "      <td>-1.1520</td>\n",
              "      <td>-0.4201</td>\n",
              "      <td>-0.0958</td>\n",
              "      <td>0.4590</td>\n",
              "      <td>0.0803</td>\n",
              "      <td>0.2250</td>\n",
              "      <td>0.5293</td>\n",
              "      <td>0.2839</td>\n",
              "      <td>-0.3494</td>\n",
              "      <td>0.2883</td>\n",
              "      <td>0.9449</td>\n",
              "      <td>-0.1646</td>\n",
              "      <td>-0.2657</td>\n",
              "      <td>-0.3372</td>\n",
              "      <td>0.3135</td>\n",
              "      <td>-0.4316</td>\n",
              "      <td>0.4773</td>\n",
              "      <td>0.2075</td>\n",
              "      <td>-0.4216</td>\n",
              "      <td>-0.1161</td>\n",
              "      <td>-0.0499</td>\n",
              "      <td>-0.2627</td>\n",
              "      <td>0.9959</td>\n",
              "      <td>-0.2483</td>\n",
              "      <td>0.2655</td>\n",
              "      <td>...</td>\n",
              "      <td>0.3905</td>\n",
              "      <td>0.7099</td>\n",
              "      <td>0.2912</td>\n",
              "      <td>0.4151</td>\n",
              "      <td>-0.2840</td>\n",
              "      <td>-0.3104</td>\n",
              "      <td>-0.6373</td>\n",
              "      <td>0.2887</td>\n",
              "      <td>-0.0765</td>\n",
              "      <td>0.2539</td>\n",
              "      <td>0.4443</td>\n",
              "      <td>0.5932</td>\n",
              "      <td>0.2031</td>\n",
              "      <td>0.7639</td>\n",
              "      <td>0.5499</td>\n",
              "      <td>-0.3322</td>\n",
              "      <td>-0.0977</td>\n",
              "      <td>0.4329</td>\n",
              "      <td>-0.2782</td>\n",
              "      <td>0.7827</td>\n",
              "      <td>0.5934</td>\n",
              "      <td>0.3402</td>\n",
              "      <td>0.1499</td>\n",
              "      <td>0.4420</td>\n",
              "      <td>0.9366</td>\n",
              "      <td>0.8193</td>\n",
              "      <td>-0.4236</td>\n",
              "      <td>0.3192</td>\n",
              "      <td>-0.4265</td>\n",
              "      <td>0.7543</td>\n",
              "      <td>0.4708</td>\n",
              "      <td>0.0230</td>\n",
              "      <td>0.2957</td>\n",
              "      <td>0.4899</td>\n",
              "      <td>0.1522</td>\n",
              "      <td>0.1241</td>\n",
              "      <td>0.6077</td>\n",
              "      <td>0.7371</td>\n",
              "      <td>0</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>48</td>\n",
              "      <td>D1</td>\n",
              "      <td>18bb41b2c</td>\n",
              "      <td>0.6280</td>\n",
              "      <td>0.5817</td>\n",
              "      <td>1.5540</td>\n",
              "      <td>-0.0764</td>\n",
              "      <td>-0.0323</td>\n",
              "      <td>1.2390</td>\n",
              "      <td>0.1715</td>\n",
              "      <td>0.2155</td>\n",
              "      <td>0.0065</td>\n",
              "      <td>1.2300</td>\n",
              "      <td>-0.4797</td>\n",
              "      <td>-0.5631</td>\n",
              "      <td>-0.0366</td>\n",
              "      <td>-1.8300</td>\n",
              "      <td>0.6057</td>\n",
              "      <td>-0.3278</td>\n",
              "      <td>0.6042</td>\n",
              "      <td>-0.3075</td>\n",
              "      <td>-0.1147</td>\n",
              "      <td>-0.0570</td>\n",
              "      <td>-0.0799</td>\n",
              "      <td>-0.8181</td>\n",
              "      <td>-1.5320</td>\n",
              "      <td>0.2307</td>\n",
              "      <td>0.4901</td>\n",
              "      <td>0.4780</td>\n",
              "      <td>-1.3970</td>\n",
              "      <td>4.6240</td>\n",
              "      <td>-0.0437</td>\n",
              "      <td>1.2870</td>\n",
              "      <td>-1.8530</td>\n",
              "      <td>0.6069</td>\n",
              "      <td>0.4290</td>\n",
              "      <td>0.1783</td>\n",
              "      <td>0.0018</td>\n",
              "      <td>...</td>\n",
              "      <td>-0.0444</td>\n",
              "      <td>0.1894</td>\n",
              "      <td>-0.0014</td>\n",
              "      <td>-2.3640</td>\n",
              "      <td>-0.4682</td>\n",
              "      <td>0.1210</td>\n",
              "      <td>-0.5177</td>\n",
              "      <td>-0.0604</td>\n",
              "      <td>0.1682</td>\n",
              "      <td>-0.4436</td>\n",
              "      <td>0.4963</td>\n",
              "      <td>0.1363</td>\n",
              "      <td>0.3335</td>\n",
              "      <td>0.9760</td>\n",
              "      <td>-0.0427</td>\n",
              "      <td>-0.1235</td>\n",
              "      <td>0.0959</td>\n",
              "      <td>0.0690</td>\n",
              "      <td>-0.9416</td>\n",
              "      <td>-0.7548</td>\n",
              "      <td>-0.1109</td>\n",
              "      <td>-0.6272</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>0.1172</td>\n",
              "      <td>0.1093</td>\n",
              "      <td>-0.3113</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>-0.0873</td>\n",
              "      <td>-0.7250</td>\n",
              "      <td>-0.6297</td>\n",
              "      <td>0.6103</td>\n",
              "      <td>0.0223</td>\n",
              "      <td>-1.3240</td>\n",
              "      <td>-0.3174</td>\n",
              "      <td>-0.6417</td>\n",
              "      <td>-0.2187</td>\n",
              "      <td>-1.4080</td>\n",
              "      <td>0.6931</td>\n",
              "      <td>3</td>\n",
              "      <td>True</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>48</td>\n",
              "      <td>D1</td>\n",
              "      <td>8c7f86626</td>\n",
              "      <td>-0.5138</td>\n",
              "      <td>-0.2491</td>\n",
              "      <td>-0.2656</td>\n",
              "      <td>0.5288</td>\n",
              "      <td>4.0620</td>\n",
              "      <td>-0.8095</td>\n",
              "      <td>-1.9590</td>\n",
              "      <td>0.1792</td>\n",
              "      <td>-0.1321</td>\n",
              "      <td>-1.0600</td>\n",
              "      <td>-0.8269</td>\n",
              "      <td>-0.3584</td>\n",
              "      <td>-0.8511</td>\n",
              "      <td>-0.5844</td>\n",
              "      <td>-2.5690</td>\n",
              "      <td>0.8183</td>\n",
              "      <td>-0.0532</td>\n",
              "      <td>-0.8554</td>\n",
              "      <td>0.1160</td>\n",
              "      <td>-2.3520</td>\n",
              "      <td>2.1200</td>\n",
              "      <td>-1.1580</td>\n",
              "      <td>-0.7191</td>\n",
              "      <td>-0.8004</td>\n",
              "      <td>-1.4670</td>\n",
              "      <td>-0.0107</td>\n",
              "      <td>-0.8995</td>\n",
              "      <td>0.2406</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-1.0890</td>\n",
              "      <td>-0.7575</td>\n",
              "      <td>0.0881</td>\n",
              "      <td>-2.7370</td>\n",
              "      <td>0.8745</td>\n",
              "      <td>0.5787</td>\n",
              "      <td>...</td>\n",
              "      <td>-2.3820</td>\n",
              "      <td>-3.7350</td>\n",
              "      <td>-2.9740</td>\n",
              "      <td>-1.4930</td>\n",
              "      <td>-1.6600</td>\n",
              "      <td>-3.1660</td>\n",
              "      <td>0.2816</td>\n",
              "      <td>-0.2990</td>\n",
              "      <td>-1.1870</td>\n",
              "      <td>-0.5044</td>\n",
              "      <td>-1.7750</td>\n",
              "      <td>-1.6120</td>\n",
              "      <td>-0.9215</td>\n",
              "      <td>-1.0810</td>\n",
              "      <td>-3.0520</td>\n",
              "      <td>-3.4470</td>\n",
              "      <td>-2.7740</td>\n",
              "      <td>-1.8460</td>\n",
              "      <td>-0.5568</td>\n",
              "      <td>-3.3960</td>\n",
              "      <td>-2.9510</td>\n",
              "      <td>-1.1550</td>\n",
              "      <td>-3.2620</td>\n",
              "      <td>-1.5390</td>\n",
              "      <td>-2.4600</td>\n",
              "      <td>-0.9417</td>\n",
              "      <td>-1.5550</td>\n",
              "      <td>0.2431</td>\n",
              "      <td>-2.0990</td>\n",
              "      <td>-0.6441</td>\n",
              "      <td>-5.6300</td>\n",
              "      <td>-1.3780</td>\n",
              "      <td>-0.8632</td>\n",
              "      <td>-1.2880</td>\n",
              "      <td>-1.6210</td>\n",
              "      <td>-0.8784</td>\n",
              "      <td>-0.3876</td>\n",
              "      <td>-0.8154</td>\n",
              "      <td>0</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D2</td>\n",
              "      <td>7cbed3131</td>\n",
              "      <td>-0.3254</td>\n",
              "      <td>-0.4009</td>\n",
              "      <td>0.9700</td>\n",
              "      <td>0.6919</td>\n",
              "      <td>1.4180</td>\n",
              "      <td>-0.8244</td>\n",
              "      <td>-0.2800</td>\n",
              "      <td>-0.1498</td>\n",
              "      <td>-0.8789</td>\n",
              "      <td>0.8630</td>\n",
              "      <td>-0.2219</td>\n",
              "      <td>-0.5121</td>\n",
              "      <td>-0.9577</td>\n",
              "      <td>1.1750</td>\n",
              "      <td>0.2042</td>\n",
              "      <td>0.1970</td>\n",
              "      <td>0.1244</td>\n",
              "      <td>-1.7090</td>\n",
              "      <td>-0.3543</td>\n",
              "      <td>-0.5160</td>\n",
              "      <td>-0.3330</td>\n",
              "      <td>-0.2685</td>\n",
              "      <td>0.7649</td>\n",
              "      <td>0.2057</td>\n",
              "      <td>1.3720</td>\n",
              "      <td>0.6835</td>\n",
              "      <td>0.8056</td>\n",
              "      <td>-0.3754</td>\n",
              "      <td>-1.2090</td>\n",
              "      <td>0.2965</td>\n",
              "      <td>-0.0712</td>\n",
              "      <td>0.6389</td>\n",
              "      <td>0.6674</td>\n",
              "      <td>-0.0783</td>\n",
              "      <td>1.1740</td>\n",
              "      <td>...</td>\n",
              "      <td>0.1535</td>\n",
              "      <td>-0.4640</td>\n",
              "      <td>-0.5943</td>\n",
              "      <td>0.3973</td>\n",
              "      <td>0.1500</td>\n",
              "      <td>0.5178</td>\n",
              "      <td>0.5159</td>\n",
              "      <td>0.6091</td>\n",
              "      <td>0.1813</td>\n",
              "      <td>-0.4249</td>\n",
              "      <td>0.7832</td>\n",
              "      <td>0.6529</td>\n",
              "      <td>0.5648</td>\n",
              "      <td>0.4817</td>\n",
              "      <td>0.0587</td>\n",
              "      <td>0.5303</td>\n",
              "      <td>0.6376</td>\n",
              "      <td>-0.3966</td>\n",
              "      <td>-1.4950</td>\n",
              "      <td>-0.9625</td>\n",
              "      <td>-0.0541</td>\n",
              "      <td>0.6273</td>\n",
              "      <td>0.4563</td>\n",
              "      <td>0.0698</td>\n",
              "      <td>0.8134</td>\n",
              "      <td>0.1924</td>\n",
              "      <td>0.6054</td>\n",
              "      <td>-0.1824</td>\n",
              "      <td>0.0042</td>\n",
              "      <td>0.0048</td>\n",
              "      <td>0.6670</td>\n",
              "      <td>1.0690</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.3031</td>\n",
              "      <td>0.1094</td>\n",
              "      <td>0.2885</td>\n",
              "      <td>-0.3786</td>\n",
              "      <td>0.7125</td>\n",
              "      <td>1</td>\n",
              "      <td>True</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>5 rows × 879 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "             id tratamento  tempo dose  ...    c-98    c-99  n_moa  ativo_moa\n",
              "0  id_000644bb2  com_droga     24   D1  ...  0.3801  0.4176      1       True\n",
              "1  id_000779bfc  com_droga     72   D1  ...  0.6077  0.7371      0      False\n",
              "2  id_000a6266a  com_droga     48   D1  ... -1.4080  0.6931      3       True\n",
              "3  id_0015fd391  com_droga     48   D1  ... -0.3876 -0.8154      0      False\n",
              "4  id_001626bd3  com_droga     72   D2  ... -0.3786  0.7125      1       True\n",
              "\n",
              "[5 rows x 879 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 12
        }
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "QseZWtW-1c0o"
      },
      "source": [
        "## **Desafio 01: Encontrar o top 10, das ações do MOA (inibidor, agonista...)**"
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "_cRbKhVw1f9-",
        "outputId": "be8a5bba-27a8-4a0c-c43f-592c118e87b9"
      },
      "source": [
        "contagem_moa = dados_resultados.drop(['id', 'n_moa', 'ativo_moa'], axis=1).sum().sort_values(ascending=False)\n",
        "contagem_moa"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "nfkb_inhibitor                                832\n",
              "proteasome_inhibitor                          726\n",
              "cyclooxygenase_inhibitor                      435\n",
              "dopamine_receptor_antagonist                  424\n",
              "serotonin_receptor_antagonist                 404\n",
              "                                             ... \n",
              "protein_phosphatase_inhibitor                   6\n",
              "autotaxin_inhibitor                             6\n",
              "diuretic                                        6\n",
              "erbb2_inhibitor                                 1\n",
              "atp-sensitive_potassium_channel_antagonist      1\n",
              "Length: 206, dtype: int64"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 13
        }
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "BoUkjrbE22nY"
      },
      "source": [
        "Uma forma de separar os dados é o usando o Filter"
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "YchB_w2a24gI",
        "outputId": "4819442b-32e2-494e-ee80-88f11226c82b"
      },
      "source": [
        "contagem_moa.filter(like='inhibitor').head(10)"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "nfkb_inhibitor              832\n",
              "proteasome_inhibitor        726\n",
              "cyclooxygenase_inhibitor    435\n",
              "dna_inhibitor               402\n",
              "cdk_inhibitor               340\n",
              "egfr_inhibitor              336\n",
              "tubulin_inhibitor           316\n",
              "pdgfr_inhibitor             297\n",
              "hmgcr_inhibitor             283\n",
              "flt3_inhibitor              279\n",
              "dtype: int64"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 14
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "teOi1vJ53QR6",
        "outputId": "6fec49ec-3112-4917-8fca-a0efd849f546"
      },
      "source": [
        "contagem_moa.filter(like='antagonist').head(10)"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "dopamine_receptor_antagonist         424\n",
              "serotonin_receptor_antagonist        404\n",
              "glutamate_receptor_antagonist        367\n",
              "adrenergic_receptor_antagonist       360\n",
              "acetylcholine_receptor_antagonist    301\n",
              "histamine_receptor_antagonist        241\n",
              "gaba_receptor_antagonist             165\n",
              "cc_chemokine_receptor_antagonist     102\n",
              "potassium_channel_antagonist          98\n",
              "adenosine_receptor_antagonist         96\n",
              "dtype: int64"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 15
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "kzQ0-lbq3QzH",
        "outputId": "063189ea-89eb-4cc4-9dce-a1f4cb2edb91"
      },
      "source": [
        "contagem_moa.filter(like='_agonist').head(10)"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "adrenergic_receptor_agonist        270\n",
              "glucocorticoid_receptor_agonist    266\n",
              "serotonin_receptor_agonist         236\n",
              "acetylcholine_receptor_agonist     190\n",
              "estrogen_receptor_agonist          158\n",
              "dopamine_receptor_agonist          121\n",
              "progesterone_receptor_agonist      119\n",
              "ppar_receptor_agonist              115\n",
              "gaba_receptor_agonist              106\n",
              "glutamate_receptor_agonist          74\n",
              "dtype: int64"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 16
        }
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "cRLc_KxF3UYY"
      },
      "source": [
        "Com isso já temos os top 10 de cada sufixo. Outra possibilidade é verificar os sufixos que ativam o MOA mais vezes."
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "0Q7zEpCl3cm1"
      },
      "source": [
        "TOP 10 SUFIXOS"
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "id": "Mkf0BtRn3TzG"
      },
      "source": [
        "contagem_moa = dados_resultados.drop(['id', 'n_moa', 'ativo_moa'], axis=1).sum().sort_values(ascending=False)\n",
        "contagem_moa = contagem_moa.reset_index()\n",
        "contagem_moa.rename(columns={'index':'MOAs',0: 'Contagem'}, inplace=True)"
      ],
      "execution_count": null,
      "outputs": []
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 415
        },
        "id": "Zow3cYop3ixZ",
        "outputId": "84b77bb4-a1b9-4e7e-bd3b-d414381aed27"
      },
      "source": [
        "contagem_moa['sufixos'] = contagem_moa['MOAs'].apply(lambda x: x.split('_')[-1])\n",
        "contagem_moa"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>MOAs</th>\n",
              "      <th>Contagem</th>\n",
              "      <th>sufixos</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>nfkb_inhibitor</td>\n",
              "      <td>832</td>\n",
              "      <td>inhibitor</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>proteasome_inhibitor</td>\n",
              "      <td>726</td>\n",
              "      <td>inhibitor</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>cyclooxygenase_inhibitor</td>\n",
              "      <td>435</td>\n",
              "      <td>inhibitor</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>dopamine_receptor_antagonist</td>\n",
              "      <td>424</td>\n",
              "      <td>antagonist</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>serotonin_receptor_antagonist</td>\n",
              "      <td>404</td>\n",
              "      <td>antagonist</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>...</th>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>201</th>\n",
              "      <td>protein_phosphatase_inhibitor</td>\n",
              "      <td>6</td>\n",
              "      <td>inhibitor</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>202</th>\n",
              "      <td>autotaxin_inhibitor</td>\n",
              "      <td>6</td>\n",
              "      <td>inhibitor</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>203</th>\n",
              "      <td>diuretic</td>\n",
              "      <td>6</td>\n",
              "      <td>diuretic</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>204</th>\n",
              "      <td>erbb2_inhibitor</td>\n",
              "      <td>1</td>\n",
              "      <td>inhibitor</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>205</th>\n",
              "      <td>atp-sensitive_potassium_channel_antagonist</td>\n",
              "      <td>1</td>\n",
              "      <td>antagonist</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>206 rows × 3 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "                                           MOAs  Contagem     sufixos\n",
              "0                                nfkb_inhibitor       832   inhibitor\n",
              "1                          proteasome_inhibitor       726   inhibitor\n",
              "2                      cyclooxygenase_inhibitor       435   inhibitor\n",
              "3                  dopamine_receptor_antagonist       424  antagonist\n",
              "4                 serotonin_receptor_antagonist       404  antagonist\n",
              "..                                          ...       ...         ...\n",
              "201               protein_phosphatase_inhibitor         6   inhibitor\n",
              "202                         autotaxin_inhibitor         6   inhibitor\n",
              "203                                    diuretic         6    diuretic\n",
              "204                             erbb2_inhibitor         1   inhibitor\n",
              "205  atp-sensitive_potassium_channel_antagonist         1  antagonist\n",
              "\n",
              "[206 rows x 3 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 18
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "id": "o0Q90aAa3lRr"
      },
      "source": [
        "contagem_MOAs_ativos_por_sufixos = contagem_moa.groupby('sufixos').sum()['Contagem'].sort_values(ascending=False)"
      ],
      "execution_count": null,
      "outputs": []
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 501
        },
        "id": "IhNlNO1G3nra",
        "outputId": "eef43eab-ecf5-464c-9730-5b1d2e3ab142"
      },
      "source": [
        "fig, ax = plt.subplots(1,1,figsize=(15,8))\n",
        "sns.barplot(y=contagem_MOAs_ativos_por_sufixos.head(10).index,\n",
        "            x=contagem_MOAs_ativos_por_sufixos.head(10).values, ax=ax, orient='h')\n",
        "ax.set_title(\"TOP 10 Sufixos mais Ativados\")\n",
        "\n",
        "plt.show()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "display_data",
          "data": {
            "image/png": "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\n",
            "text/plain": [
              "<Figure size 1080x576 with 1 Axes>"
            ]
          },
          "metadata": {
            "tags": [],
            "needs_background": "light"
          }
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "id": "_KgdXpBF3rwE"
      },
      "source": [
        "contagem_total_por_sufixo = contagem_moa.groupby('sufixos').count()['Contagem'].sort_values(ascending=False)"
      ],
      "execution_count": null,
      "outputs": []
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 501
        },
        "id": "L-MGgwZ54O7A",
        "outputId": "44121c77-db03-4694-bd18-c6147e160348"
      },
      "source": [
        "fig, ax = plt.subplots(1,1,figsize=(15,8))\n",
        "sns.barplot(y=contagem_total_por_sufixo.index[:10],\n",
        "            x=contagem_total_por_sufixo.values[:10], ax=ax, orient='h')\n",
        "ax.set_title(\"Sufixos mais frenquentes nos MOAs\")\n",
        "\n",
        "plt.show()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "display_data",
          "data": {
            "image/png": "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\n",
            "text/plain": [
              "<Figure size 1080x576 with 1 Axes>"
            ]
          },
          "metadata": {
            "tags": [],
            "needs_background": "light"
          }
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "id": "f7P6u8184VvX"
      },
      "source": [
        "contagem_sufixo_relativo = (contagem_MOAs_ativos_por_sufixos / contagem_total_por_sufixo).sort_values(ascending=False)"
      ],
      "execution_count": null,
      "outputs": []
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 501
        },
        "id": "NTdLXsZm4cuN",
        "outputId": "ba02eb17-198f-4445-88be-6c2a60e45c21"
      },
      "source": [
        "fig, ax = plt.subplots(1,1,figsize=(15,8))\n",
        "sns.barplot(y=contagem_sufixo_relativo.index[:10],\n",
        "            x=contagem_sufixo_relativo.values[:10], ax=ax, orient='h')\n",
        "ax.set_title(\"TOP 10 Sufixos mais Ativados relativamente\")\n",
        "\n",
        "plt.show()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "display_data",
          "data": {
            "image/png": "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\n",
            "text/plain": [
              "<Figure size 1080x576 with 1 Axes>"
            ]
          },
          "metadata": {
            "tags": [],
            "needs_background": "light"
          }
        }
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "vhAZrLOS4rLA"
      },
      "source": [
        "## **Desafio 02: Criar a coluna eh_controle para quando na linha tratamento == com_controle**"
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 269
        },
        "id": "qdQPOlfb4xOC",
        "outputId": "ece59ff4-6634-4f47-d0d3-9e91585e2726"
      },
      "source": [
        "dados_resultados['eh_controle'] = (dados['tratamento'] == 'com_controle')\n",
        "dados_resultados.head()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>5-alpha_reductase_inhibitor</th>\n",
              "      <th>11-beta-hsd1_inhibitor</th>\n",
              "      <th>acat_inhibitor</th>\n",
              "      <th>acetylcholine_receptor_agonist</th>\n",
              "      <th>acetylcholine_receptor_antagonist</th>\n",
              "      <th>acetylcholinesterase_inhibitor</th>\n",
              "      <th>adenosine_receptor_agonist</th>\n",
              "      <th>adenosine_receptor_antagonist</th>\n",
              "      <th>adenylyl_cyclase_activator</th>\n",
              "      <th>adrenergic_receptor_agonist</th>\n",
              "      <th>adrenergic_receptor_antagonist</th>\n",
              "      <th>akt_inhibitor</th>\n",
              "      <th>aldehyde_dehydrogenase_inhibitor</th>\n",
              "      <th>alk_inhibitor</th>\n",
              "      <th>ampk_activator</th>\n",
              "      <th>analgesic</th>\n",
              "      <th>androgen_receptor_agonist</th>\n",
              "      <th>androgen_receptor_antagonist</th>\n",
              "      <th>anesthetic_-_local</th>\n",
              "      <th>angiogenesis_inhibitor</th>\n",
              "      <th>angiotensin_receptor_antagonist</th>\n",
              "      <th>anti-inflammatory</th>\n",
              "      <th>antiarrhythmic</th>\n",
              "      <th>antibiotic</th>\n",
              "      <th>anticonvulsant</th>\n",
              "      <th>antifungal</th>\n",
              "      <th>antihistamine</th>\n",
              "      <th>antimalarial</th>\n",
              "      <th>antioxidant</th>\n",
              "      <th>antiprotozoal</th>\n",
              "      <th>antiviral</th>\n",
              "      <th>apoptosis_stimulant</th>\n",
              "      <th>aromatase_inhibitor</th>\n",
              "      <th>atm_kinase_inhibitor</th>\n",
              "      <th>atp-sensitive_potassium_channel_antagonist</th>\n",
              "      <th>atp_synthase_inhibitor</th>\n",
              "      <th>atpase_inhibitor</th>\n",
              "      <th>atr_kinase_inhibitor</th>\n",
              "      <th>aurora_kinase_inhibitor</th>\n",
              "      <th>...</th>\n",
              "      <th>raf_inhibitor</th>\n",
              "      <th>ras_gtpase_inhibitor</th>\n",
              "      <th>retinoid_receptor_agonist</th>\n",
              "      <th>retinoid_receptor_antagonist</th>\n",
              "      <th>rho_associated_kinase_inhibitor</th>\n",
              "      <th>ribonucleoside_reductase_inhibitor</th>\n",
              "      <th>rna_polymerase_inhibitor</th>\n",
              "      <th>serotonin_receptor_agonist</th>\n",
              "      <th>serotonin_receptor_antagonist</th>\n",
              "      <th>serotonin_reuptake_inhibitor</th>\n",
              "      <th>sigma_receptor_agonist</th>\n",
              "      <th>sigma_receptor_antagonist</th>\n",
              "      <th>smoothened_receptor_antagonist</th>\n",
              "      <th>sodium_channel_inhibitor</th>\n",
              "      <th>sphingosine_receptor_agonist</th>\n",
              "      <th>src_inhibitor</th>\n",
              "      <th>steroid</th>\n",
              "      <th>syk_inhibitor</th>\n",
              "      <th>tachykinin_antagonist</th>\n",
              "      <th>tgf-beta_receptor_inhibitor</th>\n",
              "      <th>thrombin_inhibitor</th>\n",
              "      <th>thymidylate_synthase_inhibitor</th>\n",
              "      <th>tlr_agonist</th>\n",
              "      <th>tlr_antagonist</th>\n",
              "      <th>tnf_inhibitor</th>\n",
              "      <th>topoisomerase_inhibitor</th>\n",
              "      <th>transient_receptor_potential_channel_antagonist</th>\n",
              "      <th>tropomyosin_receptor_kinase_inhibitor</th>\n",
              "      <th>trpv_agonist</th>\n",
              "      <th>trpv_antagonist</th>\n",
              "      <th>tubulin_inhibitor</th>\n",
              "      <th>tyrosine_kinase_inhibitor</th>\n",
              "      <th>ubiquitin_specific_protease_inhibitor</th>\n",
              "      <th>vegfr_inhibitor</th>\n",
              "      <th>vitamin_b</th>\n",
              "      <th>vitamin_d_receptor_agonist</th>\n",
              "      <th>wnt_inhibitor</th>\n",
              "      <th>n_moa</th>\n",
              "      <th>ativo_moa</th>\n",
              "      <th>eh_controle</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "      <td>True</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>False</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>3</td>\n",
              "      <td>True</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>False</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "      <td>True</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>5 rows × 210 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "             id  5-alpha_reductase_inhibitor  ...  ativo_moa  eh_controle\n",
              "0  id_000644bb2                            0  ...       True        False\n",
              "1  id_000779bfc                            0  ...      False        False\n",
              "2  id_000a6266a                            0  ...       True        False\n",
              "3  id_0015fd391                            0  ...      False        False\n",
              "4  id_001626bd3                            0  ...       True        False\n",
              "\n",
              "[5 rows x 210 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 25
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 251
        },
        "id": "bh3JfLAx4xhr",
        "outputId": "53cc9786-82b5-485b-ecf3-f8db6e035d31"
      },
      "source": [
        "dados_combinados = pd.merge(dados, dados_resultados[['id','n_moa', 'ativo_moa','eh_controle']], on='id')\n",
        "dados_combinados.head()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>tratamento</th>\n",
              "      <th>tempo</th>\n",
              "      <th>dose</th>\n",
              "      <th>composto</th>\n",
              "      <th>g-0</th>\n",
              "      <th>g-1</th>\n",
              "      <th>g-2</th>\n",
              "      <th>g-3</th>\n",
              "      <th>g-4</th>\n",
              "      <th>g-5</th>\n",
              "      <th>g-6</th>\n",
              "      <th>g-7</th>\n",
              "      <th>g-8</th>\n",
              "      <th>g-9</th>\n",
              "      <th>g-10</th>\n",
              "      <th>g-11</th>\n",
              "      <th>g-12</th>\n",
              "      <th>g-13</th>\n",
              "      <th>g-14</th>\n",
              "      <th>g-15</th>\n",
              "      <th>g-16</th>\n",
              "      <th>g-17</th>\n",
              "      <th>g-18</th>\n",
              "      <th>g-19</th>\n",
              "      <th>g-20</th>\n",
              "      <th>g-21</th>\n",
              "      <th>g-22</th>\n",
              "      <th>g-23</th>\n",
              "      <th>g-24</th>\n",
              "      <th>g-25</th>\n",
              "      <th>g-26</th>\n",
              "      <th>g-27</th>\n",
              "      <th>g-28</th>\n",
              "      <th>g-29</th>\n",
              "      <th>g-30</th>\n",
              "      <th>g-31</th>\n",
              "      <th>g-32</th>\n",
              "      <th>g-33</th>\n",
              "      <th>g-34</th>\n",
              "      <th>...</th>\n",
              "      <th>c-63</th>\n",
              "      <th>c-64</th>\n",
              "      <th>c-65</th>\n",
              "      <th>c-66</th>\n",
              "      <th>c-67</th>\n",
              "      <th>c-68</th>\n",
              "      <th>c-69</th>\n",
              "      <th>c-70</th>\n",
              "      <th>c-71</th>\n",
              "      <th>c-72</th>\n",
              "      <th>c-73</th>\n",
              "      <th>c-74</th>\n",
              "      <th>c-75</th>\n",
              "      <th>c-76</th>\n",
              "      <th>c-77</th>\n",
              "      <th>c-78</th>\n",
              "      <th>c-79</th>\n",
              "      <th>c-80</th>\n",
              "      <th>c-81</th>\n",
              "      <th>c-82</th>\n",
              "      <th>c-83</th>\n",
              "      <th>c-84</th>\n",
              "      <th>c-85</th>\n",
              "      <th>c-86</th>\n",
              "      <th>c-87</th>\n",
              "      <th>c-88</th>\n",
              "      <th>c-89</th>\n",
              "      <th>c-90</th>\n",
              "      <th>c-91</th>\n",
              "      <th>c-92</th>\n",
              "      <th>c-93</th>\n",
              "      <th>c-94</th>\n",
              "      <th>c-95</th>\n",
              "      <th>c-96</th>\n",
              "      <th>c-97</th>\n",
              "      <th>c-98</th>\n",
              "      <th>c-99</th>\n",
              "      <th>n_moa</th>\n",
              "      <th>ativo_moa</th>\n",
              "      <th>eh_controle</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>24</td>\n",
              "      <td>D1</td>\n",
              "      <td>b68db1d53</td>\n",
              "      <td>1.0620</td>\n",
              "      <td>0.5577</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-0.6208</td>\n",
              "      <td>-0.1944</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>-1.0220</td>\n",
              "      <td>-0.0326</td>\n",
              "      <td>0.5548</td>\n",
              "      <td>-0.0921</td>\n",
              "      <td>1.1830</td>\n",
              "      <td>0.1530</td>\n",
              "      <td>0.5574</td>\n",
              "      <td>-0.4015</td>\n",
              "      <td>0.1789</td>\n",
              "      <td>-0.6528</td>\n",
              "      <td>-0.7969</td>\n",
              "      <td>0.6342</td>\n",
              "      <td>0.1778</td>\n",
              "      <td>-0.3694</td>\n",
              "      <td>-0.5688</td>\n",
              "      <td>-1.1360</td>\n",
              "      <td>-1.1880</td>\n",
              "      <td>0.6940</td>\n",
              "      <td>0.4393</td>\n",
              "      <td>0.2664</td>\n",
              "      <td>0.1907</td>\n",
              "      <td>0.1628</td>\n",
              "      <td>-0.2853</td>\n",
              "      <td>0.5819</td>\n",
              "      <td>0.2934</td>\n",
              "      <td>-0.5584</td>\n",
              "      <td>-0.0916</td>\n",
              "      <td>-0.3010</td>\n",
              "      <td>-0.1537</td>\n",
              "      <td>...</td>\n",
              "      <td>0.8427</td>\n",
              "      <td>0.1042</td>\n",
              "      <td>0.1403</td>\n",
              "      <td>0.1758</td>\n",
              "      <td>1.2570</td>\n",
              "      <td>-0.5979</td>\n",
              "      <td>1.2250</td>\n",
              "      <td>-0.0553</td>\n",
              "      <td>0.7351</td>\n",
              "      <td>0.5810</td>\n",
              "      <td>0.9590</td>\n",
              "      <td>0.2427</td>\n",
              "      <td>0.0495</td>\n",
              "      <td>0.4141</td>\n",
              "      <td>0.8432</td>\n",
              "      <td>0.6162</td>\n",
              "      <td>-0.7318</td>\n",
              "      <td>1.2120</td>\n",
              "      <td>0.6362</td>\n",
              "      <td>-0.4427</td>\n",
              "      <td>0.1288</td>\n",
              "      <td>1.4840</td>\n",
              "      <td>0.1799</td>\n",
              "      <td>0.5367</td>\n",
              "      <td>-0.1111</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>0.6685</td>\n",
              "      <td>0.2862</td>\n",
              "      <td>0.2584</td>\n",
              "      <td>0.8076</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.1912</td>\n",
              "      <td>0.6584</td>\n",
              "      <td>-0.3981</td>\n",
              "      <td>0.2139</td>\n",
              "      <td>0.3801</td>\n",
              "      <td>0.4176</td>\n",
              "      <td>1</td>\n",
              "      <td>True</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D1</td>\n",
              "      <td>df89a8e5a</td>\n",
              "      <td>0.0743</td>\n",
              "      <td>0.4087</td>\n",
              "      <td>0.2991</td>\n",
              "      <td>0.0604</td>\n",
              "      <td>1.0190</td>\n",
              "      <td>0.5207</td>\n",
              "      <td>0.2341</td>\n",
              "      <td>0.3372</td>\n",
              "      <td>-0.4047</td>\n",
              "      <td>0.8507</td>\n",
              "      <td>-1.1520</td>\n",
              "      <td>-0.4201</td>\n",
              "      <td>-0.0958</td>\n",
              "      <td>0.4590</td>\n",
              "      <td>0.0803</td>\n",
              "      <td>0.2250</td>\n",
              "      <td>0.5293</td>\n",
              "      <td>0.2839</td>\n",
              "      <td>-0.3494</td>\n",
              "      <td>0.2883</td>\n",
              "      <td>0.9449</td>\n",
              "      <td>-0.1646</td>\n",
              "      <td>-0.2657</td>\n",
              "      <td>-0.3372</td>\n",
              "      <td>0.3135</td>\n",
              "      <td>-0.4316</td>\n",
              "      <td>0.4773</td>\n",
              "      <td>0.2075</td>\n",
              "      <td>-0.4216</td>\n",
              "      <td>-0.1161</td>\n",
              "      <td>-0.0499</td>\n",
              "      <td>-0.2627</td>\n",
              "      <td>0.9959</td>\n",
              "      <td>-0.2483</td>\n",
              "      <td>0.2655</td>\n",
              "      <td>...</td>\n",
              "      <td>0.7099</td>\n",
              "      <td>0.2912</td>\n",
              "      <td>0.4151</td>\n",
              "      <td>-0.2840</td>\n",
              "      <td>-0.3104</td>\n",
              "      <td>-0.6373</td>\n",
              "      <td>0.2887</td>\n",
              "      <td>-0.0765</td>\n",
              "      <td>0.2539</td>\n",
              "      <td>0.4443</td>\n",
              "      <td>0.5932</td>\n",
              "      <td>0.2031</td>\n",
              "      <td>0.7639</td>\n",
              "      <td>0.5499</td>\n",
              "      <td>-0.3322</td>\n",
              "      <td>-0.0977</td>\n",
              "      <td>0.4329</td>\n",
              "      <td>-0.2782</td>\n",
              "      <td>0.7827</td>\n",
              "      <td>0.5934</td>\n",
              "      <td>0.3402</td>\n",
              "      <td>0.1499</td>\n",
              "      <td>0.4420</td>\n",
              "      <td>0.9366</td>\n",
              "      <td>0.8193</td>\n",
              "      <td>-0.4236</td>\n",
              "      <td>0.3192</td>\n",
              "      <td>-0.4265</td>\n",
              "      <td>0.7543</td>\n",
              "      <td>0.4708</td>\n",
              "      <td>0.0230</td>\n",
              "      <td>0.2957</td>\n",
              "      <td>0.4899</td>\n",
              "      <td>0.1522</td>\n",
              "      <td>0.1241</td>\n",
              "      <td>0.6077</td>\n",
              "      <td>0.7371</td>\n",
              "      <td>0</td>\n",
              "      <td>False</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>48</td>\n",
              "      <td>D1</td>\n",
              "      <td>18bb41b2c</td>\n",
              "      <td>0.6280</td>\n",
              "      <td>0.5817</td>\n",
              "      <td>1.5540</td>\n",
              "      <td>-0.0764</td>\n",
              "      <td>-0.0323</td>\n",
              "      <td>1.2390</td>\n",
              "      <td>0.1715</td>\n",
              "      <td>0.2155</td>\n",
              "      <td>0.0065</td>\n",
              "      <td>1.2300</td>\n",
              "      <td>-0.4797</td>\n",
              "      <td>-0.5631</td>\n",
              "      <td>-0.0366</td>\n",
              "      <td>-1.8300</td>\n",
              "      <td>0.6057</td>\n",
              "      <td>-0.3278</td>\n",
              "      <td>0.6042</td>\n",
              "      <td>-0.3075</td>\n",
              "      <td>-0.1147</td>\n",
              "      <td>-0.0570</td>\n",
              "      <td>-0.0799</td>\n",
              "      <td>-0.8181</td>\n",
              "      <td>-1.5320</td>\n",
              "      <td>0.2307</td>\n",
              "      <td>0.4901</td>\n",
              "      <td>0.4780</td>\n",
              "      <td>-1.3970</td>\n",
              "      <td>4.6240</td>\n",
              "      <td>-0.0437</td>\n",
              "      <td>1.2870</td>\n",
              "      <td>-1.8530</td>\n",
              "      <td>0.6069</td>\n",
              "      <td>0.4290</td>\n",
              "      <td>0.1783</td>\n",
              "      <td>0.0018</td>\n",
              "      <td>...</td>\n",
              "      <td>0.1894</td>\n",
              "      <td>-0.0014</td>\n",
              "      <td>-2.3640</td>\n",
              "      <td>-0.4682</td>\n",
              "      <td>0.1210</td>\n",
              "      <td>-0.5177</td>\n",
              "      <td>-0.0604</td>\n",
              "      <td>0.1682</td>\n",
              "      <td>-0.4436</td>\n",
              "      <td>0.4963</td>\n",
              "      <td>0.1363</td>\n",
              "      <td>0.3335</td>\n",
              "      <td>0.9760</td>\n",
              "      <td>-0.0427</td>\n",
              "      <td>-0.1235</td>\n",
              "      <td>0.0959</td>\n",
              "      <td>0.0690</td>\n",
              "      <td>-0.9416</td>\n",
              "      <td>-0.7548</td>\n",
              "      <td>-0.1109</td>\n",
              "      <td>-0.6272</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>0.1172</td>\n",
              "      <td>0.1093</td>\n",
              "      <td>-0.3113</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>-0.0873</td>\n",
              "      <td>-0.7250</td>\n",
              "      <td>-0.6297</td>\n",
              "      <td>0.6103</td>\n",
              "      <td>0.0223</td>\n",
              "      <td>-1.3240</td>\n",
              "      <td>-0.3174</td>\n",
              "      <td>-0.6417</td>\n",
              "      <td>-0.2187</td>\n",
              "      <td>-1.4080</td>\n",
              "      <td>0.6931</td>\n",
              "      <td>3</td>\n",
              "      <td>True</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>48</td>\n",
              "      <td>D1</td>\n",
              "      <td>8c7f86626</td>\n",
              "      <td>-0.5138</td>\n",
              "      <td>-0.2491</td>\n",
              "      <td>-0.2656</td>\n",
              "      <td>0.5288</td>\n",
              "      <td>4.0620</td>\n",
              "      <td>-0.8095</td>\n",
              "      <td>-1.9590</td>\n",
              "      <td>0.1792</td>\n",
              "      <td>-0.1321</td>\n",
              "      <td>-1.0600</td>\n",
              "      <td>-0.8269</td>\n",
              "      <td>-0.3584</td>\n",
              "      <td>-0.8511</td>\n",
              "      <td>-0.5844</td>\n",
              "      <td>-2.5690</td>\n",
              "      <td>0.8183</td>\n",
              "      <td>-0.0532</td>\n",
              "      <td>-0.8554</td>\n",
              "      <td>0.1160</td>\n",
              "      <td>-2.3520</td>\n",
              "      <td>2.1200</td>\n",
              "      <td>-1.1580</td>\n",
              "      <td>-0.7191</td>\n",
              "      <td>-0.8004</td>\n",
              "      <td>-1.4670</td>\n",
              "      <td>-0.0107</td>\n",
              "      <td>-0.8995</td>\n",
              "      <td>0.2406</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-1.0890</td>\n",
              "      <td>-0.7575</td>\n",
              "      <td>0.0881</td>\n",
              "      <td>-2.7370</td>\n",
              "      <td>0.8745</td>\n",
              "      <td>0.5787</td>\n",
              "      <td>...</td>\n",
              "      <td>-3.7350</td>\n",
              "      <td>-2.9740</td>\n",
              "      <td>-1.4930</td>\n",
              "      <td>-1.6600</td>\n",
              "      <td>-3.1660</td>\n",
              "      <td>0.2816</td>\n",
              "      <td>-0.2990</td>\n",
              "      <td>-1.1870</td>\n",
              "      <td>-0.5044</td>\n",
              "      <td>-1.7750</td>\n",
              "      <td>-1.6120</td>\n",
              "      <td>-0.9215</td>\n",
              "      <td>-1.0810</td>\n",
              "      <td>-3.0520</td>\n",
              "      <td>-3.4470</td>\n",
              "      <td>-2.7740</td>\n",
              "      <td>-1.8460</td>\n",
              "      <td>-0.5568</td>\n",
              "      <td>-3.3960</td>\n",
              "      <td>-2.9510</td>\n",
              "      <td>-1.1550</td>\n",
              "      <td>-3.2620</td>\n",
              "      <td>-1.5390</td>\n",
              "      <td>-2.4600</td>\n",
              "      <td>-0.9417</td>\n",
              "      <td>-1.5550</td>\n",
              "      <td>0.2431</td>\n",
              "      <td>-2.0990</td>\n",
              "      <td>-0.6441</td>\n",
              "      <td>-5.6300</td>\n",
              "      <td>-1.3780</td>\n",
              "      <td>-0.8632</td>\n",
              "      <td>-1.2880</td>\n",
              "      <td>-1.6210</td>\n",
              "      <td>-0.8784</td>\n",
              "      <td>-0.3876</td>\n",
              "      <td>-0.8154</td>\n",
              "      <td>0</td>\n",
              "      <td>False</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>72</td>\n",
              "      <td>D2</td>\n",
              "      <td>7cbed3131</td>\n",
              "      <td>-0.3254</td>\n",
              "      <td>-0.4009</td>\n",
              "      <td>0.9700</td>\n",
              "      <td>0.6919</td>\n",
              "      <td>1.4180</td>\n",
              "      <td>-0.8244</td>\n",
              "      <td>-0.2800</td>\n",
              "      <td>-0.1498</td>\n",
              "      <td>-0.8789</td>\n",
              "      <td>0.8630</td>\n",
              "      <td>-0.2219</td>\n",
              "      <td>-0.5121</td>\n",
              "      <td>-0.9577</td>\n",
              "      <td>1.1750</td>\n",
              "      <td>0.2042</td>\n",
              "      <td>0.1970</td>\n",
              "      <td>0.1244</td>\n",
              "      <td>-1.7090</td>\n",
              "      <td>-0.3543</td>\n",
              "      <td>-0.5160</td>\n",
              "      <td>-0.3330</td>\n",
              "      <td>-0.2685</td>\n",
              "      <td>0.7649</td>\n",
              "      <td>0.2057</td>\n",
              "      <td>1.3720</td>\n",
              "      <td>0.6835</td>\n",
              "      <td>0.8056</td>\n",
              "      <td>-0.3754</td>\n",
              "      <td>-1.2090</td>\n",
              "      <td>0.2965</td>\n",
              "      <td>-0.0712</td>\n",
              "      <td>0.6389</td>\n",
              "      <td>0.6674</td>\n",
              "      <td>-0.0783</td>\n",
              "      <td>1.1740</td>\n",
              "      <td>...</td>\n",
              "      <td>-0.4640</td>\n",
              "      <td>-0.5943</td>\n",
              "      <td>0.3973</td>\n",
              "      <td>0.1500</td>\n",
              "      <td>0.5178</td>\n",
              "      <td>0.5159</td>\n",
              "      <td>0.6091</td>\n",
              "      <td>0.1813</td>\n",
              "      <td>-0.4249</td>\n",
              "      <td>0.7832</td>\n",
              "      <td>0.6529</td>\n",
              "      <td>0.5648</td>\n",
              "      <td>0.4817</td>\n",
              "      <td>0.0587</td>\n",
              "      <td>0.5303</td>\n",
              "      <td>0.6376</td>\n",
              "      <td>-0.3966</td>\n",
              "      <td>-1.4950</td>\n",
              "      <td>-0.9625</td>\n",
              "      <td>-0.0541</td>\n",
              "      <td>0.6273</td>\n",
              "      <td>0.4563</td>\n",
              "      <td>0.0698</td>\n",
              "      <td>0.8134</td>\n",
              "      <td>0.1924</td>\n",
              "      <td>0.6054</td>\n",
              "      <td>-0.1824</td>\n",
              "      <td>0.0042</td>\n",
              "      <td>0.0048</td>\n",
              "      <td>0.6670</td>\n",
              "      <td>1.0690</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.3031</td>\n",
              "      <td>0.1094</td>\n",
              "      <td>0.2885</td>\n",
              "      <td>-0.3786</td>\n",
              "      <td>0.7125</td>\n",
              "      <td>1</td>\n",
              "      <td>True</td>\n",
              "      <td>False</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>5 rows × 880 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "             id tratamento  tempo dose  ...    c-99  n_moa  ativo_moa  eh_controle\n",
              "0  id_000644bb2  com_droga     24   D1  ...  0.4176      1       True        False\n",
              "1  id_000779bfc  com_droga     72   D1  ...  0.7371      0      False        False\n",
              "2  id_000a6266a  com_droga     48   D1  ...  0.6931      3       True        False\n",
              "3  id_0015fd391  com_droga     48   D1  ... -0.8154      0      False        False\n",
              "4  id_001626bd3  com_droga     72   D2  ...  0.7125      1       True        False\n",
              "\n",
              "[5 rows x 880 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 26
        }
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "o57IvKLm5CXg"
      },
      "source": [
        "## **Desafio 03: Criar três colunas para indicar o tempo 24, 48, 72**"
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 435
        },
        "id": "cV1SR-QP5Llr",
        "outputId": "feb7f55e-b3b2-4ef3-f908-d2be61bc0117"
      },
      "source": [
        "pd.get_dummies(dados, columns=['tempo'])"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>tratamento</th>\n",
              "      <th>dose</th>\n",
              "      <th>composto</th>\n",
              "      <th>g-0</th>\n",
              "      <th>g-1</th>\n",
              "      <th>g-2</th>\n",
              "      <th>g-3</th>\n",
              "      <th>g-4</th>\n",
              "      <th>g-5</th>\n",
              "      <th>g-6</th>\n",
              "      <th>g-7</th>\n",
              "      <th>g-8</th>\n",
              "      <th>g-9</th>\n",
              "      <th>g-10</th>\n",
              "      <th>g-11</th>\n",
              "      <th>g-12</th>\n",
              "      <th>g-13</th>\n",
              "      <th>g-14</th>\n",
              "      <th>g-15</th>\n",
              "      <th>g-16</th>\n",
              "      <th>g-17</th>\n",
              "      <th>g-18</th>\n",
              "      <th>g-19</th>\n",
              "      <th>g-20</th>\n",
              "      <th>g-21</th>\n",
              "      <th>g-22</th>\n",
              "      <th>g-23</th>\n",
              "      <th>g-24</th>\n",
              "      <th>g-25</th>\n",
              "      <th>g-26</th>\n",
              "      <th>g-27</th>\n",
              "      <th>g-28</th>\n",
              "      <th>g-29</th>\n",
              "      <th>g-30</th>\n",
              "      <th>g-31</th>\n",
              "      <th>g-32</th>\n",
              "      <th>g-33</th>\n",
              "      <th>g-34</th>\n",
              "      <th>g-35</th>\n",
              "      <th>...</th>\n",
              "      <th>c-63</th>\n",
              "      <th>c-64</th>\n",
              "      <th>c-65</th>\n",
              "      <th>c-66</th>\n",
              "      <th>c-67</th>\n",
              "      <th>c-68</th>\n",
              "      <th>c-69</th>\n",
              "      <th>c-70</th>\n",
              "      <th>c-71</th>\n",
              "      <th>c-72</th>\n",
              "      <th>c-73</th>\n",
              "      <th>c-74</th>\n",
              "      <th>c-75</th>\n",
              "      <th>c-76</th>\n",
              "      <th>c-77</th>\n",
              "      <th>c-78</th>\n",
              "      <th>c-79</th>\n",
              "      <th>c-80</th>\n",
              "      <th>c-81</th>\n",
              "      <th>c-82</th>\n",
              "      <th>c-83</th>\n",
              "      <th>c-84</th>\n",
              "      <th>c-85</th>\n",
              "      <th>c-86</th>\n",
              "      <th>c-87</th>\n",
              "      <th>c-88</th>\n",
              "      <th>c-89</th>\n",
              "      <th>c-90</th>\n",
              "      <th>c-91</th>\n",
              "      <th>c-92</th>\n",
              "      <th>c-93</th>\n",
              "      <th>c-94</th>\n",
              "      <th>c-95</th>\n",
              "      <th>c-96</th>\n",
              "      <th>c-97</th>\n",
              "      <th>c-98</th>\n",
              "      <th>c-99</th>\n",
              "      <th>tempo_24</th>\n",
              "      <th>tempo_48</th>\n",
              "      <th>tempo_72</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>D1</td>\n",
              "      <td>b68db1d53</td>\n",
              "      <td>1.0620</td>\n",
              "      <td>0.5577</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-0.6208</td>\n",
              "      <td>-0.1944</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>-1.0220</td>\n",
              "      <td>-0.0326</td>\n",
              "      <td>0.5548</td>\n",
              "      <td>-0.0921</td>\n",
              "      <td>1.1830</td>\n",
              "      <td>0.1530</td>\n",
              "      <td>0.5574</td>\n",
              "      <td>-0.4015</td>\n",
              "      <td>0.1789</td>\n",
              "      <td>-0.6528</td>\n",
              "      <td>-0.7969</td>\n",
              "      <td>0.6342</td>\n",
              "      <td>0.1778</td>\n",
              "      <td>-0.3694</td>\n",
              "      <td>-0.5688</td>\n",
              "      <td>-1.1360</td>\n",
              "      <td>-1.1880</td>\n",
              "      <td>0.6940</td>\n",
              "      <td>0.4393</td>\n",
              "      <td>0.2664</td>\n",
              "      <td>0.1907</td>\n",
              "      <td>0.1628</td>\n",
              "      <td>-0.2853</td>\n",
              "      <td>0.5819</td>\n",
              "      <td>0.2934</td>\n",
              "      <td>-0.5584</td>\n",
              "      <td>-0.0916</td>\n",
              "      <td>-0.3010</td>\n",
              "      <td>-0.1537</td>\n",
              "      <td>0.2198</td>\n",
              "      <td>...</td>\n",
              "      <td>0.8427</td>\n",
              "      <td>0.1042</td>\n",
              "      <td>0.1403</td>\n",
              "      <td>0.1758</td>\n",
              "      <td>1.2570</td>\n",
              "      <td>-0.5979</td>\n",
              "      <td>1.2250</td>\n",
              "      <td>-0.0553</td>\n",
              "      <td>0.7351</td>\n",
              "      <td>0.5810</td>\n",
              "      <td>0.9590</td>\n",
              "      <td>0.2427</td>\n",
              "      <td>0.0495</td>\n",
              "      <td>0.4141</td>\n",
              "      <td>0.8432</td>\n",
              "      <td>0.6162</td>\n",
              "      <td>-0.7318</td>\n",
              "      <td>1.2120</td>\n",
              "      <td>0.6362</td>\n",
              "      <td>-0.4427</td>\n",
              "      <td>0.1288</td>\n",
              "      <td>1.4840</td>\n",
              "      <td>0.1799</td>\n",
              "      <td>0.5367</td>\n",
              "      <td>-0.1111</td>\n",
              "      <td>-1.0120</td>\n",
              "      <td>0.6685</td>\n",
              "      <td>0.2862</td>\n",
              "      <td>0.2584</td>\n",
              "      <td>0.8076</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.1912</td>\n",
              "      <td>0.6584</td>\n",
              "      <td>-0.3981</td>\n",
              "      <td>0.2139</td>\n",
              "      <td>0.3801</td>\n",
              "      <td>0.4176</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>D1</td>\n",
              "      <td>df89a8e5a</td>\n",
              "      <td>0.0743</td>\n",
              "      <td>0.4087</td>\n",
              "      <td>0.2991</td>\n",
              "      <td>0.0604</td>\n",
              "      <td>1.0190</td>\n",
              "      <td>0.5207</td>\n",
              "      <td>0.2341</td>\n",
              "      <td>0.3372</td>\n",
              "      <td>-0.4047</td>\n",
              "      <td>0.8507</td>\n",
              "      <td>-1.1520</td>\n",
              "      <td>-0.4201</td>\n",
              "      <td>-0.0958</td>\n",
              "      <td>0.4590</td>\n",
              "      <td>0.0803</td>\n",
              "      <td>0.2250</td>\n",
              "      <td>0.5293</td>\n",
              "      <td>0.2839</td>\n",
              "      <td>-0.3494</td>\n",
              "      <td>0.2883</td>\n",
              "      <td>0.9449</td>\n",
              "      <td>-0.1646</td>\n",
              "      <td>-0.2657</td>\n",
              "      <td>-0.3372</td>\n",
              "      <td>0.3135</td>\n",
              "      <td>-0.4316</td>\n",
              "      <td>0.4773</td>\n",
              "      <td>0.2075</td>\n",
              "      <td>-0.4216</td>\n",
              "      <td>-0.1161</td>\n",
              "      <td>-0.0499</td>\n",
              "      <td>-0.2627</td>\n",
              "      <td>0.9959</td>\n",
              "      <td>-0.2483</td>\n",
              "      <td>0.2655</td>\n",
              "      <td>-0.2102</td>\n",
              "      <td>...</td>\n",
              "      <td>0.7099</td>\n",
              "      <td>0.2912</td>\n",
              "      <td>0.4151</td>\n",
              "      <td>-0.2840</td>\n",
              "      <td>-0.3104</td>\n",
              "      <td>-0.6373</td>\n",
              "      <td>0.2887</td>\n",
              "      <td>-0.0765</td>\n",
              "      <td>0.2539</td>\n",
              "      <td>0.4443</td>\n",
              "      <td>0.5932</td>\n",
              "      <td>0.2031</td>\n",
              "      <td>0.7639</td>\n",
              "      <td>0.5499</td>\n",
              "      <td>-0.3322</td>\n",
              "      <td>-0.0977</td>\n",
              "      <td>0.4329</td>\n",
              "      <td>-0.2782</td>\n",
              "      <td>0.7827</td>\n",
              "      <td>0.5934</td>\n",
              "      <td>0.3402</td>\n",
              "      <td>0.1499</td>\n",
              "      <td>0.4420</td>\n",
              "      <td>0.9366</td>\n",
              "      <td>0.8193</td>\n",
              "      <td>-0.4236</td>\n",
              "      <td>0.3192</td>\n",
              "      <td>-0.4265</td>\n",
              "      <td>0.7543</td>\n",
              "      <td>0.4708</td>\n",
              "      <td>0.0230</td>\n",
              "      <td>0.2957</td>\n",
              "      <td>0.4899</td>\n",
              "      <td>0.1522</td>\n",
              "      <td>0.1241</td>\n",
              "      <td>0.6077</td>\n",
              "      <td>0.7371</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>D1</td>\n",
              "      <td>18bb41b2c</td>\n",
              "      <td>0.6280</td>\n",
              "      <td>0.5817</td>\n",
              "      <td>1.5540</td>\n",
              "      <td>-0.0764</td>\n",
              "      <td>-0.0323</td>\n",
              "      <td>1.2390</td>\n",
              "      <td>0.1715</td>\n",
              "      <td>0.2155</td>\n",
              "      <td>0.0065</td>\n",
              "      <td>1.2300</td>\n",
              "      <td>-0.4797</td>\n",
              "      <td>-0.5631</td>\n",
              "      <td>-0.0366</td>\n",
              "      <td>-1.8300</td>\n",
              "      <td>0.6057</td>\n",
              "      <td>-0.3278</td>\n",
              "      <td>0.6042</td>\n",
              "      <td>-0.3075</td>\n",
              "      <td>-0.1147</td>\n",
              "      <td>-0.0570</td>\n",
              "      <td>-0.0799</td>\n",
              "      <td>-0.8181</td>\n",
              "      <td>-1.5320</td>\n",
              "      <td>0.2307</td>\n",
              "      <td>0.4901</td>\n",
              "      <td>0.4780</td>\n",
              "      <td>-1.3970</td>\n",
              "      <td>4.6240</td>\n",
              "      <td>-0.0437</td>\n",
              "      <td>1.2870</td>\n",
              "      <td>-1.8530</td>\n",
              "      <td>0.6069</td>\n",
              "      <td>0.4290</td>\n",
              "      <td>0.1783</td>\n",
              "      <td>0.0018</td>\n",
              "      <td>-1.1800</td>\n",
              "      <td>...</td>\n",
              "      <td>0.1894</td>\n",
              "      <td>-0.0014</td>\n",
              "      <td>-2.3640</td>\n",
              "      <td>-0.4682</td>\n",
              "      <td>0.1210</td>\n",
              "      <td>-0.5177</td>\n",
              "      <td>-0.0604</td>\n",
              "      <td>0.1682</td>\n",
              "      <td>-0.4436</td>\n",
              "      <td>0.4963</td>\n",
              "      <td>0.1363</td>\n",
              "      <td>0.3335</td>\n",
              "      <td>0.9760</td>\n",
              "      <td>-0.0427</td>\n",
              "      <td>-0.1235</td>\n",
              "      <td>0.0959</td>\n",
              "      <td>0.0690</td>\n",
              "      <td>-0.9416</td>\n",
              "      <td>-0.7548</td>\n",
              "      <td>-0.1109</td>\n",
              "      <td>-0.6272</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>0.1172</td>\n",
              "      <td>0.1093</td>\n",
              "      <td>-0.3113</td>\n",
              "      <td>0.3019</td>\n",
              "      <td>-0.0873</td>\n",
              "      <td>-0.7250</td>\n",
              "      <td>-0.6297</td>\n",
              "      <td>0.6103</td>\n",
              "      <td>0.0223</td>\n",
              "      <td>-1.3240</td>\n",
              "      <td>-0.3174</td>\n",
              "      <td>-0.6417</td>\n",
              "      <td>-0.2187</td>\n",
              "      <td>-1.4080</td>\n",
              "      <td>0.6931</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>D1</td>\n",
              "      <td>8c7f86626</td>\n",
              "      <td>-0.5138</td>\n",
              "      <td>-0.2491</td>\n",
              "      <td>-0.2656</td>\n",
              "      <td>0.5288</td>\n",
              "      <td>4.0620</td>\n",
              "      <td>-0.8095</td>\n",
              "      <td>-1.9590</td>\n",
              "      <td>0.1792</td>\n",
              "      <td>-0.1321</td>\n",
              "      <td>-1.0600</td>\n",
              "      <td>-0.8269</td>\n",
              "      <td>-0.3584</td>\n",
              "      <td>-0.8511</td>\n",
              "      <td>-0.5844</td>\n",
              "      <td>-2.5690</td>\n",
              "      <td>0.8183</td>\n",
              "      <td>-0.0532</td>\n",
              "      <td>-0.8554</td>\n",
              "      <td>0.1160</td>\n",
              "      <td>-2.3520</td>\n",
              "      <td>2.1200</td>\n",
              "      <td>-1.1580</td>\n",
              "      <td>-0.7191</td>\n",
              "      <td>-0.8004</td>\n",
              "      <td>-1.4670</td>\n",
              "      <td>-0.0107</td>\n",
              "      <td>-0.8995</td>\n",
              "      <td>0.2406</td>\n",
              "      <td>-0.2479</td>\n",
              "      <td>-1.0890</td>\n",
              "      <td>-0.7575</td>\n",
              "      <td>0.0881</td>\n",
              "      <td>-2.7370</td>\n",
              "      <td>0.8745</td>\n",
              "      <td>0.5787</td>\n",
              "      <td>-1.6740</td>\n",
              "      <td>...</td>\n",
              "      <td>-3.7350</td>\n",
              "      <td>-2.9740</td>\n",
              "      <td>-1.4930</td>\n",
              "      <td>-1.6600</td>\n",
              "      <td>-3.1660</td>\n",
              "      <td>0.2816</td>\n",
              "      <td>-0.2990</td>\n",
              "      <td>-1.1870</td>\n",
              "      <td>-0.5044</td>\n",
              "      <td>-1.7750</td>\n",
              "      <td>-1.6120</td>\n",
              "      <td>-0.9215</td>\n",
              "      <td>-1.0810</td>\n",
              "      <td>-3.0520</td>\n",
              "      <td>-3.4470</td>\n",
              "      <td>-2.7740</td>\n",
              "      <td>-1.8460</td>\n",
              "      <td>-0.5568</td>\n",
              "      <td>-3.3960</td>\n",
              "      <td>-2.9510</td>\n",
              "      <td>-1.1550</td>\n",
              "      <td>-3.2620</td>\n",
              "      <td>-1.5390</td>\n",
              "      <td>-2.4600</td>\n",
              "      <td>-0.9417</td>\n",
              "      <td>-1.5550</td>\n",
              "      <td>0.2431</td>\n",
              "      <td>-2.0990</td>\n",
              "      <td>-0.6441</td>\n",
              "      <td>-5.6300</td>\n",
              "      <td>-1.3780</td>\n",
              "      <td>-0.8632</td>\n",
              "      <td>-1.2880</td>\n",
              "      <td>-1.6210</td>\n",
              "      <td>-0.8784</td>\n",
              "      <td>-0.3876</td>\n",
              "      <td>-0.8154</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>D2</td>\n",
              "      <td>7cbed3131</td>\n",
              "      <td>-0.3254</td>\n",
              "      <td>-0.4009</td>\n",
              "      <td>0.9700</td>\n",
              "      <td>0.6919</td>\n",
              "      <td>1.4180</td>\n",
              "      <td>-0.8244</td>\n",
              "      <td>-0.2800</td>\n",
              "      <td>-0.1498</td>\n",
              "      <td>-0.8789</td>\n",
              "      <td>0.8630</td>\n",
              "      <td>-0.2219</td>\n",
              "      <td>-0.5121</td>\n",
              "      <td>-0.9577</td>\n",
              "      <td>1.1750</td>\n",
              "      <td>0.2042</td>\n",
              "      <td>0.1970</td>\n",
              "      <td>0.1244</td>\n",
              "      <td>-1.7090</td>\n",
              "      <td>-0.3543</td>\n",
              "      <td>-0.5160</td>\n",
              "      <td>-0.3330</td>\n",
              "      <td>-0.2685</td>\n",
              "      <td>0.7649</td>\n",
              "      <td>0.2057</td>\n",
              "      <td>1.3720</td>\n",
              "      <td>0.6835</td>\n",
              "      <td>0.8056</td>\n",
              "      <td>-0.3754</td>\n",
              "      <td>-1.2090</td>\n",
              "      <td>0.2965</td>\n",
              "      <td>-0.0712</td>\n",
              "      <td>0.6389</td>\n",
              "      <td>0.6674</td>\n",
              "      <td>-0.0783</td>\n",
              "      <td>1.1740</td>\n",
              "      <td>-0.7110</td>\n",
              "      <td>...</td>\n",
              "      <td>-0.4640</td>\n",
              "      <td>-0.5943</td>\n",
              "      <td>0.3973</td>\n",
              "      <td>0.1500</td>\n",
              "      <td>0.5178</td>\n",
              "      <td>0.5159</td>\n",
              "      <td>0.6091</td>\n",
              "      <td>0.1813</td>\n",
              "      <td>-0.4249</td>\n",
              "      <td>0.7832</td>\n",
              "      <td>0.6529</td>\n",
              "      <td>0.5648</td>\n",
              "      <td>0.4817</td>\n",
              "      <td>0.0587</td>\n",
              "      <td>0.5303</td>\n",
              "      <td>0.6376</td>\n",
              "      <td>-0.3966</td>\n",
              "      <td>-1.4950</td>\n",
              "      <td>-0.9625</td>\n",
              "      <td>-0.0541</td>\n",
              "      <td>0.6273</td>\n",
              "      <td>0.4563</td>\n",
              "      <td>0.0698</td>\n",
              "      <td>0.8134</td>\n",
              "      <td>0.1924</td>\n",
              "      <td>0.6054</td>\n",
              "      <td>-0.1824</td>\n",
              "      <td>0.0042</td>\n",
              "      <td>0.0048</td>\n",
              "      <td>0.6670</td>\n",
              "      <td>1.0690</td>\n",
              "      <td>0.5523</td>\n",
              "      <td>-0.3031</td>\n",
              "      <td>0.1094</td>\n",
              "      <td>0.2885</td>\n",
              "      <td>-0.3786</td>\n",
              "      <td>0.7125</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>...</th>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "      <td>...</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23809</th>\n",
              "      <td>id_fffb1ceed</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>D2</td>\n",
              "      <td>df1d0a5a1</td>\n",
              "      <td>0.1394</td>\n",
              "      <td>-0.0636</td>\n",
              "      <td>-0.1112</td>\n",
              "      <td>-0.5080</td>\n",
              "      <td>-0.4713</td>\n",
              "      <td>0.7201</td>\n",
              "      <td>0.5773</td>\n",
              "      <td>0.3055</td>\n",
              "      <td>-0.4726</td>\n",
              "      <td>0.1269</td>\n",
              "      <td>0.2531</td>\n",
              "      <td>0.1730</td>\n",
              "      <td>-0.4532</td>\n",
              "      <td>-1.0790</td>\n",
              "      <td>0.2474</td>\n",
              "      <td>-0.4550</td>\n",
              "      <td>0.3588</td>\n",
              "      <td>0.1600</td>\n",
              "      <td>-0.7362</td>\n",
              "      <td>-0.1103</td>\n",
              "      <td>0.8550</td>\n",
              "      <td>-0.4139</td>\n",
              "      <td>0.5541</td>\n",
              "      <td>0.2310</td>\n",
              "      <td>-0.5573</td>\n",
              "      <td>-0.4397</td>\n",
              "      <td>-0.9260</td>\n",
              "      <td>-0.2424</td>\n",
              "      <td>-0.6686</td>\n",
              "      <td>0.2326</td>\n",
              "      <td>0.6456</td>\n",
              "      <td>0.0136</td>\n",
              "      <td>-0.5141</td>\n",
              "      <td>-0.6320</td>\n",
              "      <td>0.7166</td>\n",
              "      <td>-0.1736</td>\n",
              "      <td>...</td>\n",
              "      <td>0.4420</td>\n",
              "      <td>0.9641</td>\n",
              "      <td>-0.1846</td>\n",
              "      <td>-0.0014</td>\n",
              "      <td>0.3154</td>\n",
              "      <td>-0.2071</td>\n",
              "      <td>-0.6158</td>\n",
              "      <td>-0.2977</td>\n",
              "      <td>0.0992</td>\n",
              "      <td>0.6838</td>\n",
              "      <td>0.5259</td>\n",
              "      <td>0.7882</td>\n",
              "      <td>0.3119</td>\n",
              "      <td>-0.7697</td>\n",
              "      <td>0.2203</td>\n",
              "      <td>-1.0710</td>\n",
              "      <td>0.5979</td>\n",
              "      <td>0.0848</td>\n",
              "      <td>-0.2555</td>\n",
              "      <td>0.6293</td>\n",
              "      <td>1.1660</td>\n",
              "      <td>0.3329</td>\n",
              "      <td>0.2754</td>\n",
              "      <td>0.4108</td>\n",
              "      <td>-0.1252</td>\n",
              "      <td>-0.2340</td>\n",
              "      <td>0.2267</td>\n",
              "      <td>0.1969</td>\n",
              "      <td>0.0262</td>\n",
              "      <td>-0.8121</td>\n",
              "      <td>0.3434</td>\n",
              "      <td>0.5372</td>\n",
              "      <td>-0.3246</td>\n",
              "      <td>0.0631</td>\n",
              "      <td>0.9171</td>\n",
              "      <td>0.5258</td>\n",
              "      <td>0.4680</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23810</th>\n",
              "      <td>id_fffb70c0c</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>D2</td>\n",
              "      <td>ecf3b6b74</td>\n",
              "      <td>-1.3260</td>\n",
              "      <td>0.3478</td>\n",
              "      <td>-0.3743</td>\n",
              "      <td>0.9905</td>\n",
              "      <td>-0.7178</td>\n",
              "      <td>0.6621</td>\n",
              "      <td>-0.2252</td>\n",
              "      <td>-0.5565</td>\n",
              "      <td>0.5112</td>\n",
              "      <td>0.6727</td>\n",
              "      <td>-0.1851</td>\n",
              "      <td>2.8650</td>\n",
              "      <td>-0.2140</td>\n",
              "      <td>-0.6153</td>\n",
              "      <td>0.8362</td>\n",
              "      <td>0.5584</td>\n",
              "      <td>-0.2589</td>\n",
              "      <td>0.1292</td>\n",
              "      <td>0.0148</td>\n",
              "      <td>0.0949</td>\n",
              "      <td>-0.2182</td>\n",
              "      <td>-0.9235</td>\n",
              "      <td>0.0749</td>\n",
              "      <td>-1.5910</td>\n",
              "      <td>-0.8359</td>\n",
              "      <td>-0.9217</td>\n",
              "      <td>0.3013</td>\n",
              "      <td>0.1716</td>\n",
              "      <td>0.0880</td>\n",
              "      <td>0.1842</td>\n",
              "      <td>0.1835</td>\n",
              "      <td>0.5436</td>\n",
              "      <td>-0.0533</td>\n",
              "      <td>-0.0491</td>\n",
              "      <td>0.9543</td>\n",
              "      <td>0.4626</td>\n",
              "      <td>...</td>\n",
              "      <td>0.8129</td>\n",
              "      <td>-0.1514</td>\n",
              "      <td>-0.4652</td>\n",
              "      <td>-0.7390</td>\n",
              "      <td>-1.3270</td>\n",
              "      <td>0.9925</td>\n",
              "      <td>1.0570</td>\n",
              "      <td>-0.3355</td>\n",
              "      <td>-0.2555</td>\n",
              "      <td>0.8219</td>\n",
              "      <td>0.6995</td>\n",
              "      <td>-0.2942</td>\n",
              "      <td>0.2408</td>\n",
              "      <td>-0.7781</td>\n",
              "      <td>-0.0929</td>\n",
              "      <td>-0.0329</td>\n",
              "      <td>0.0781</td>\n",
              "      <td>-1.4440</td>\n",
              "      <td>-0.0921</td>\n",
              "      <td>0.3188</td>\n",
              "      <td>-1.1080</td>\n",
              "      <td>0.4895</td>\n",
              "      <td>-0.2144</td>\n",
              "      <td>1.0960</td>\n",
              "      <td>0.3335</td>\n",
              "      <td>0.4444</td>\n",
              "      <td>-1.1130</td>\n",
              "      <td>0.4286</td>\n",
              "      <td>0.4426</td>\n",
              "      <td>0.0423</td>\n",
              "      <td>-0.3195</td>\n",
              "      <td>-0.8086</td>\n",
              "      <td>-0.9798</td>\n",
              "      <td>-0.2084</td>\n",
              "      <td>-0.1224</td>\n",
              "      <td>-0.2715</td>\n",
              "      <td>0.3689</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23811</th>\n",
              "      <td>id_fffc1c3f4</td>\n",
              "      <td>com_controle</td>\n",
              "      <td>D2</td>\n",
              "      <td>cacb2b860</td>\n",
              "      <td>0.3942</td>\n",
              "      <td>0.3756</td>\n",
              "      <td>0.3109</td>\n",
              "      <td>-0.7389</td>\n",
              "      <td>0.5505</td>\n",
              "      <td>-0.0159</td>\n",
              "      <td>-0.2541</td>\n",
              "      <td>0.1745</td>\n",
              "      <td>-0.0340</td>\n",
              "      <td>0.4865</td>\n",
              "      <td>-0.1854</td>\n",
              "      <td>0.0716</td>\n",
              "      <td>0.1729</td>\n",
              "      <td>-0.0434</td>\n",
              "      <td>0.1542</td>\n",
              "      <td>-0.2192</td>\n",
              "      <td>-0.0302</td>\n",
              "      <td>-0.4218</td>\n",
              "      <td>0.4057</td>\n",
              "      <td>-0.5372</td>\n",
              "      <td>0.1521</td>\n",
              "      <td>-0.2651</td>\n",
              "      <td>0.2310</td>\n",
              "      <td>-0.8101</td>\n",
              "      <td>0.4943</td>\n",
              "      <td>0.6905</td>\n",
              "      <td>-0.3720</td>\n",
              "      <td>-1.4110</td>\n",
              "      <td>0.4516</td>\n",
              "      <td>1.2300</td>\n",
              "      <td>-0.1949</td>\n",
              "      <td>-1.3280</td>\n",
              "      <td>-0.4276</td>\n",
              "      <td>-0.0040</td>\n",
              "      <td>-0.3086</td>\n",
              "      <td>-0.2355</td>\n",
              "      <td>...</td>\n",
              "      <td>0.4718</td>\n",
              "      <td>-0.2020</td>\n",
              "      <td>0.2783</td>\n",
              "      <td>0.4934</td>\n",
              "      <td>0.4144</td>\n",
              "      <td>0.5449</td>\n",
              "      <td>1.4690</td>\n",
              "      <td>-0.6142</td>\n",
              "      <td>0.6068</td>\n",
              "      <td>0.3434</td>\n",
              "      <td>0.9880</td>\n",
              "      <td>-0.0468</td>\n",
              "      <td>-0.1882</td>\n",
              "      <td>-0.0087</td>\n",
              "      <td>-0.0356</td>\n",
              "      <td>0.5718</td>\n",
              "      <td>0.4971</td>\n",
              "      <td>0.1057</td>\n",
              "      <td>0.2111</td>\n",
              "      <td>0.6992</td>\n",
              "      <td>0.0708</td>\n",
              "      <td>0.6169</td>\n",
              "      <td>0.2248</td>\n",
              "      <td>0.5994</td>\n",
              "      <td>0.2689</td>\n",
              "      <td>0.0305</td>\n",
              "      <td>1.2320</td>\n",
              "      <td>0.5409</td>\n",
              "      <td>0.3755</td>\n",
              "      <td>0.7343</td>\n",
              "      <td>0.2807</td>\n",
              "      <td>0.4116</td>\n",
              "      <td>0.6422</td>\n",
              "      <td>0.2256</td>\n",
              "      <td>0.7592</td>\n",
              "      <td>0.6656</td>\n",
              "      <td>0.3808</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23812</th>\n",
              "      <td>id_fffcb9e7c</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>D1</td>\n",
              "      <td>8b87a7a83</td>\n",
              "      <td>0.6660</td>\n",
              "      <td>0.2324</td>\n",
              "      <td>0.4392</td>\n",
              "      <td>0.2044</td>\n",
              "      <td>0.8531</td>\n",
              "      <td>-0.0343</td>\n",
              "      <td>0.0323</td>\n",
              "      <td>0.0463</td>\n",
              "      <td>0.4299</td>\n",
              "      <td>-0.7985</td>\n",
              "      <td>0.5742</td>\n",
              "      <td>0.1421</td>\n",
              "      <td>2.2700</td>\n",
              "      <td>0.2046</td>\n",
              "      <td>0.5363</td>\n",
              "      <td>-1.7330</td>\n",
              "      <td>0.1450</td>\n",
              "      <td>0.6097</td>\n",
              "      <td>0.2024</td>\n",
              "      <td>0.9865</td>\n",
              "      <td>-0.7805</td>\n",
              "      <td>0.9608</td>\n",
              "      <td>0.3440</td>\n",
              "      <td>2.7650</td>\n",
              "      <td>0.4925</td>\n",
              "      <td>0.6698</td>\n",
              "      <td>0.2374</td>\n",
              "      <td>-0.3372</td>\n",
              "      <td>0.8771</td>\n",
              "      <td>-2.6560</td>\n",
              "      <td>-0.2000</td>\n",
              "      <td>-0.2043</td>\n",
              "      <td>0.6797</td>\n",
              "      <td>-0.0248</td>\n",
              "      <td>-0.0927</td>\n",
              "      <td>1.8480</td>\n",
              "      <td>...</td>\n",
              "      <td>0.9261</td>\n",
              "      <td>0.4419</td>\n",
              "      <td>0.0295</td>\n",
              "      <td>0.4220</td>\n",
              "      <td>0.4677</td>\n",
              "      <td>-0.1184</td>\n",
              "      <td>0.4524</td>\n",
              "      <td>0.4135</td>\n",
              "      <td>0.1356</td>\n",
              "      <td>-0.5801</td>\n",
              "      <td>0.0411</td>\n",
              "      <td>1.0240</td>\n",
              "      <td>1.0340</td>\n",
              "      <td>-0.0270</td>\n",
              "      <td>-0.4194</td>\n",
              "      <td>0.7403</td>\n",
              "      <td>-0.6793</td>\n",
              "      <td>-0.1423</td>\n",
              "      <td>0.7307</td>\n",
              "      <td>0.7946</td>\n",
              "      <td>-0.0650</td>\n",
              "      <td>0.9038</td>\n",
              "      <td>0.2324</td>\n",
              "      <td>0.9676</td>\n",
              "      <td>1.0940</td>\n",
              "      <td>0.4290</td>\n",
              "      <td>0.5187</td>\n",
              "      <td>-0.1105</td>\n",
              "      <td>0.4258</td>\n",
              "      <td>-0.2012</td>\n",
              "      <td>0.1506</td>\n",
              "      <td>1.5230</td>\n",
              "      <td>0.7101</td>\n",
              "      <td>0.1732</td>\n",
              "      <td>0.7015</td>\n",
              "      <td>-0.6290</td>\n",
              "      <td>0.0740</td>\n",
              "      <td>1</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>23813</th>\n",
              "      <td>id_ffffdd77b</td>\n",
              "      <td>com_droga</td>\n",
              "      <td>D1</td>\n",
              "      <td>972f41291</td>\n",
              "      <td>-0.8598</td>\n",
              "      <td>1.0240</td>\n",
              "      <td>-0.1361</td>\n",
              "      <td>0.7952</td>\n",
              "      <td>-0.3611</td>\n",
              "      <td>-3.6750</td>\n",
              "      <td>-1.2420</td>\n",
              "      <td>0.9146</td>\n",
              "      <td>3.0790</td>\n",
              "      <td>1.2460</td>\n",
              "      <td>1.9460</td>\n",
              "      <td>1.4370</td>\n",
              "      <td>2.9780</td>\n",
              "      <td>2.2370</td>\n",
              "      <td>-0.6818</td>\n",
              "      <td>0.6870</td>\n",
              "      <td>-1.1060</td>\n",
              "      <td>0.0182</td>\n",
              "      <td>-0.9247</td>\n",
              "      <td>-0.0738</td>\n",
              "      <td>-0.1919</td>\n",
              "      <td>-0.7722</td>\n",
              "      <td>-1.4050</td>\n",
              "      <td>-1.0050</td>\n",
              "      <td>-1.1170</td>\n",
              "      <td>-0.5293</td>\n",
              "      <td>-1.1720</td>\n",
              "      <td>-0.2885</td>\n",
              "      <td>0.1599</td>\n",
              "      <td>-0.4250</td>\n",
              "      <td>0.3591</td>\n",
              "      <td>-0.1420</td>\n",
              "      <td>-0.9530</td>\n",
              "      <td>-0.2005</td>\n",
              "      <td>-1.8340</td>\n",
              "      <td>-0.5768</td>\n",
              "      <td>...</td>\n",
              "      <td>-4.7130</td>\n",
              "      <td>-1.7250</td>\n",
              "      <td>-3.8650</td>\n",
              "      <td>-3.0800</td>\n",
              "      <td>-4.1530</td>\n",
              "      <td>-1.2030</td>\n",
              "      <td>-1.1690</td>\n",
              "      <td>-4.1460</td>\n",
              "      <td>-1.2670</td>\n",
              "      <td>-1.1300</td>\n",
              "      <td>-2.4390</td>\n",
              "      <td>0.1591</td>\n",
              "      <td>-2.2490</td>\n",
              "      <td>-2.5860</td>\n",
              "      <td>-1.9520</td>\n",
              "      <td>-2.1810</td>\n",
              "      <td>-4.6690</td>\n",
              "      <td>-3.9450</td>\n",
              "      <td>-2.9560</td>\n",
              "      <td>-2.7930</td>\n",
              "      <td>-2.1560</td>\n",
              "      <td>-2.4100</td>\n",
              "      <td>-1.8190</td>\n",
              "      <td>-3.3480</td>\n",
              "      <td>-0.1414</td>\n",
              "      <td>-2.6430</td>\n",
              "      <td>-2.5810</td>\n",
              "      <td>-3.3890</td>\n",
              "      <td>-1.7450</td>\n",
              "      <td>-6.6300</td>\n",
              "      <td>-4.0950</td>\n",
              "      <td>-7.3860</td>\n",
              "      <td>-1.4160</td>\n",
              "      <td>-3.5770</td>\n",
              "      <td>-0.4775</td>\n",
              "      <td>-2.1500</td>\n",
              "      <td>-4.2520</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>1</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>23814 rows × 879 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "                 id    tratamento dose  ... tempo_24  tempo_48  tempo_72\n",
              "0      id_000644bb2     com_droga   D1  ...        1         0         0\n",
              "1      id_000779bfc     com_droga   D1  ...        0         0         1\n",
              "2      id_000a6266a     com_droga   D1  ...        0         1         0\n",
              "3      id_0015fd391     com_droga   D1  ...        0         1         0\n",
              "4      id_001626bd3     com_droga   D2  ...        0         0         1\n",
              "...             ...           ...  ...  ...      ...       ...       ...\n",
              "23809  id_fffb1ceed     com_droga   D2  ...        1         0         0\n",
              "23810  id_fffb70c0c     com_droga   D2  ...        1         0         0\n",
              "23811  id_fffc1c3f4  com_controle   D2  ...        0         1         0\n",
              "23812  id_fffcb9e7c     com_droga   D1  ...        1         0         0\n",
              "23813  id_ffffdd77b     com_droga   D1  ...        0         0         1\n",
              "\n",
              "[23814 rows x 879 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 27
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "id": "_GK8X1OC5ROs"
      },
      "source": [
        ""
      ],
      "execution_count": null,
      "outputs": []
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "kF8JJNjN5fSp"
      },
      "source": [
        "## **Desafio 04: Estudar sobre combinações de DF**"
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "nCB_CFhg5iXF"
      },
      "source": [
        "https://pandas.pydata.org/pandas-docs/stable/user_guide/merging.html"
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "KKAFUzM75qU_"
      },
      "source": [
        "## **Desafio 05: Fazer análise mais detalhada considerando tempo e dose, para comparar as distribuições (Escolher uma droga e comparar com controle)**"
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "cN9e_qiv5xFy",
        "outputId": "b8244ace-535a-473d-d634-c52cdffd8064"
      },
      "source": [
        "composto_principal = dados_combinados['composto'].value_counts().index[0:2]\n",
        "composto_principal"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "Index(['cacb2b860', '87d714366'], dtype='object')"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 28
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 339
        },
        "id": "fAHRCWNB5zkn",
        "outputId": "e9399386-a2c3-45e0-c962-bf3e5a9b1e5e"
      },
      "source": [
        "fig, (ax1, ax2, ax3) = plt.subplots(1,3,figsize=(15,5))\n",
        "\n",
        "sns.boxplot(data = dados_combinados.query('composto in @composto_principal & tempo == 24'), y= 'g-0', x='composto',\n",
        "            hue='ativo_moa', order=composto_principal, ax=ax1)\n",
        "\n",
        "sns.boxplot(data = dados_combinados.query('composto in @composto_principal & tempo == 48'), y= 'g-0', x='composto',\n",
        "            hue='ativo_moa', order=composto_principal, ax=ax2)\n",
        "\n",
        "sns.boxplot(data = dados_combinados.query('composto in @composto_principal & tempo == 48'), y= 'g-0', x='composto',\n",
        "            hue='ativo_moa', order=composto_principal, ax=ax3)\n",
        "\n",
        "plt.show()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "display_data",
          "data": {
            "image/png": "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\n",
            "text/plain": [
              "<Figure size 1080x360 with 3 Axes>"
            ]
          },
          "metadata": {
            "tags": [],
            "needs_background": "light"
          }
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 339
        },
        "id": "X7fmNgG752au",
        "outputId": "b36a3c5e-bf06-4be4-f391-473dfed8c99a"
      },
      "source": [
        "fig, (ax1, ax2) = plt.subplots(1,2,figsize=(15,5))\n",
        "\n",
        "sns.boxplot(data = dados_combinados.query('composto in @composto_principal & dose == \"D1\"'), y= 'g-0', x='composto',\n",
        "            hue='ativo_moa', order=composto_principal, ax=ax1)\n",
        "\n",
        "sns.boxplot(data = dados_combinados.query('composto in @composto_principal & dose == \"D2\"'), y= 'g-0', x='composto',\n",
        "            hue='ativo_moa', order=composto_principal, ax=ax2)\n",
        "\n",
        "plt.show()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "display_data",
          "data": {
            "image/png": "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\n",
            "text/plain": [
              "<Figure size 1080x360 with 2 Axes>"
            ]
          },
          "metadata": {
            "tags": [],
            "needs_background": "light"
          }
        }
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "ItLntkJk6XXg"
      },
      "source": [
        "## **Desafio 06: Descobrir se tem algum composto que dependendo da configuração do experimento, ativa ou não ativa algum MOA - (Precisamos melhorar isso)**"
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "UWRUk5aN54qZ",
        "outputId": "8f9b9440-782a-4478-c68a-ce2a035400c9"
      },
      "source": [
        "np.mean([True, True, True])"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "1.0"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 32
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "i4wLUEo66e7v",
        "outputId": "a05b9cb7-b484-439a-9dbb-09fa69c32a89"
      },
      "source": [
        "np.mean([False, False, False])"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "0.0"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 33
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "MXmh72l06is4",
        "outputId": "27e34594-434e-41a8-b271-69558e90268d"
      },
      "source": [
        "np.mean([True, False, True])"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "0.6666666666666666"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 34
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/"
        },
        "id": "ogJkaHcS6kr6",
        "outputId": "3b8fba98-f003-45bd-b598-7da1c6807ee9"
      },
      "source": [
        "dados_combinados.groupby('composto').ativo_moa.mean().value_counts()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/plain": [
              "True     2076\n",
              "False    1213\n",
              "Name: ativo_moa, dtype: int64"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 35
        }
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "ZVYaFOL_6qoN"
      },
      "source": [
        "Temos apenas Trues e Falses como resultados. Isso significa que quando um composto realiza a ativação essa ativação já aparece em cada uma das fases."
      ]
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "iD-0rHGP6zpY"
      },
      "source": [
        "## **Desafio 07: Descobrir se tem algum composto que dependendo da configuração do experimento, ativa MOAs diferentes**"
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "colab": {
          "base_uri": "https://localhost:8080/",
          "height": 269
        },
        "id": "-rFEezx461-Z",
        "outputId": "62a94c10-6e79-447d-b68d-92e25f75f3d5"
      },
      "source": [
        "dados_combinados_resultados = pd.merge(dados[['id', 'composto']],\n",
        "                                       dados_resultados.drop(['n_moa', 'ativo_moa',\n",
        "                                                              'eh_controle'], axis=1), on='id')\n",
        "dados_combinados_resultados.head()"
      ],
      "execution_count": null,
      "outputs": [
        {
          "output_type": "execute_result",
          "data": {
            "text/html": [
              "<div>\n",
              "<style scoped>\n",
              "    .dataframe tbody tr th:only-of-type {\n",
              "        vertical-align: middle;\n",
              "    }\n",
              "\n",
              "    .dataframe tbody tr th {\n",
              "        vertical-align: top;\n",
              "    }\n",
              "\n",
              "    .dataframe thead th {\n",
              "        text-align: right;\n",
              "    }\n",
              "</style>\n",
              "<table border=\"1\" class=\"dataframe\">\n",
              "  <thead>\n",
              "    <tr style=\"text-align: right;\">\n",
              "      <th></th>\n",
              "      <th>id</th>\n",
              "      <th>composto</th>\n",
              "      <th>5-alpha_reductase_inhibitor</th>\n",
              "      <th>11-beta-hsd1_inhibitor</th>\n",
              "      <th>acat_inhibitor</th>\n",
              "      <th>acetylcholine_receptor_agonist</th>\n",
              "      <th>acetylcholine_receptor_antagonist</th>\n",
              "      <th>acetylcholinesterase_inhibitor</th>\n",
              "      <th>adenosine_receptor_agonist</th>\n",
              "      <th>adenosine_receptor_antagonist</th>\n",
              "      <th>adenylyl_cyclase_activator</th>\n",
              "      <th>adrenergic_receptor_agonist</th>\n",
              "      <th>adrenergic_receptor_antagonist</th>\n",
              "      <th>akt_inhibitor</th>\n",
              "      <th>aldehyde_dehydrogenase_inhibitor</th>\n",
              "      <th>alk_inhibitor</th>\n",
              "      <th>ampk_activator</th>\n",
              "      <th>analgesic</th>\n",
              "      <th>androgen_receptor_agonist</th>\n",
              "      <th>androgen_receptor_antagonist</th>\n",
              "      <th>anesthetic_-_local</th>\n",
              "      <th>angiogenesis_inhibitor</th>\n",
              "      <th>angiotensin_receptor_antagonist</th>\n",
              "      <th>anti-inflammatory</th>\n",
              "      <th>antiarrhythmic</th>\n",
              "      <th>antibiotic</th>\n",
              "      <th>anticonvulsant</th>\n",
              "      <th>antifungal</th>\n",
              "      <th>antihistamine</th>\n",
              "      <th>antimalarial</th>\n",
              "      <th>antioxidant</th>\n",
              "      <th>antiprotozoal</th>\n",
              "      <th>antiviral</th>\n",
              "      <th>apoptosis_stimulant</th>\n",
              "      <th>aromatase_inhibitor</th>\n",
              "      <th>atm_kinase_inhibitor</th>\n",
              "      <th>atp-sensitive_potassium_channel_antagonist</th>\n",
              "      <th>atp_synthase_inhibitor</th>\n",
              "      <th>atpase_inhibitor</th>\n",
              "      <th>atr_kinase_inhibitor</th>\n",
              "      <th>...</th>\n",
              "      <th>protein_synthesis_inhibitor</th>\n",
              "      <th>protein_tyrosine_kinase_inhibitor</th>\n",
              "      <th>radiopaque_medium</th>\n",
              "      <th>raf_inhibitor</th>\n",
              "      <th>ras_gtpase_inhibitor</th>\n",
              "      <th>retinoid_receptor_agonist</th>\n",
              "      <th>retinoid_receptor_antagonist</th>\n",
              "      <th>rho_associated_kinase_inhibitor</th>\n",
              "      <th>ribonucleoside_reductase_inhibitor</th>\n",
              "      <th>rna_polymerase_inhibitor</th>\n",
              "      <th>serotonin_receptor_agonist</th>\n",
              "      <th>serotonin_receptor_antagonist</th>\n",
              "      <th>serotonin_reuptake_inhibitor</th>\n",
              "      <th>sigma_receptor_agonist</th>\n",
              "      <th>sigma_receptor_antagonist</th>\n",
              "      <th>smoothened_receptor_antagonist</th>\n",
              "      <th>sodium_channel_inhibitor</th>\n",
              "      <th>sphingosine_receptor_agonist</th>\n",
              "      <th>src_inhibitor</th>\n",
              "      <th>steroid</th>\n",
              "      <th>syk_inhibitor</th>\n",
              "      <th>tachykinin_antagonist</th>\n",
              "      <th>tgf-beta_receptor_inhibitor</th>\n",
              "      <th>thrombin_inhibitor</th>\n",
              "      <th>thymidylate_synthase_inhibitor</th>\n",
              "      <th>tlr_agonist</th>\n",
              "      <th>tlr_antagonist</th>\n",
              "      <th>tnf_inhibitor</th>\n",
              "      <th>topoisomerase_inhibitor</th>\n",
              "      <th>transient_receptor_potential_channel_antagonist</th>\n",
              "      <th>tropomyosin_receptor_kinase_inhibitor</th>\n",
              "      <th>trpv_agonist</th>\n",
              "      <th>trpv_antagonist</th>\n",
              "      <th>tubulin_inhibitor</th>\n",
              "      <th>tyrosine_kinase_inhibitor</th>\n",
              "      <th>ubiquitin_specific_protease_inhibitor</th>\n",
              "      <th>vegfr_inhibitor</th>\n",
              "      <th>vitamin_b</th>\n",
              "      <th>vitamin_d_receptor_agonist</th>\n",
              "      <th>wnt_inhibitor</th>\n",
              "    </tr>\n",
              "  </thead>\n",
              "  <tbody>\n",
              "    <tr>\n",
              "      <th>0</th>\n",
              "      <td>id_000644bb2</td>\n",
              "      <td>b68db1d53</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>1</th>\n",
              "      <td>id_000779bfc</td>\n",
              "      <td>df89a8e5a</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>2</th>\n",
              "      <td>id_000a6266a</td>\n",
              "      <td>18bb41b2c</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>3</th>\n",
              "      <td>id_0015fd391</td>\n",
              "      <td>8c7f86626</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "    <tr>\n",
              "      <th>4</th>\n",
              "      <td>id_001626bd3</td>\n",
              "      <td>7cbed3131</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>...</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "      <td>0</td>\n",
              "    </tr>\n",
              "  </tbody>\n",
              "</table>\n",
              "<p>5 rows × 208 columns</p>\n",
              "</div>"
            ],
            "text/plain": [
              "             id   composto  ...  vitamin_d_receptor_agonist  wnt_inhibitor\n",
              "0  id_000644bb2  b68db1d53  ...                           0              0\n",
              "1  id_000779bfc  df89a8e5a  ...                           0              0\n",
              "2  id_000a6266a  18bb41b2c  ...                           0              0\n",
              "3  id_0015fd391  8c7f86626  ...                           0              0\n",
              "4  id_001626bd3  7cbed3131  ...                           0              0\n",
              "\n",
              "[5 rows x 208 columns]"
            ]
          },
          "metadata": {
            "tags": []
          },
          "execution_count": 40
        }
      ]
    },
    {
      "cell_type": "code",
      "metadata": {
        "id": "qOSFtX9r65El"
      },
      "source": [
        "def verifica(linhas_do_resultado):\n",
        "# Resultado ainda será criado \n",
        "  assinaturas = linhas_do_resultado.iloc[:,2:].value_counts()\n",
        "  lista = []\n",
        "#Verificando se temos mais de uma assinatura para cada composto\n",
        "  if len(assinaturas) > 1:\n",
        "    lista.append(assinaturas)\n",
        "  return lista"
      ],
      "execution_count": null,
      "outputs": []
    },
    {
      "cell_type": "code",
      "metadata": {
        "id": "mO6BpSBc7fL7"
      },
      "source": [
        "# Pegando cada Composto e utilizando a função criada para verificar sua assinatura\n",
        "resultado = dados_combinados_resultados.groupby('composto').apply(verifica)"
      ],
      "execution_count": null,
      "outputs": []
    },
    {
      "cell_type": "code",
      "metadata": {
        "id": "Z2bjQZb27knh"
      },
      "source": [
        "for linha in resultado:\n",
        "  if len(linha):\n",
        "    print(linha)"
      ],
      "execution_count": null,
      "outputs": []
    },
    {
      "cell_type": "markdown",
      "metadata": {
        "id": "0hZXtlXu7pA-"
      },
      "source": [
        "Como nosso resultado foi apenas de listas vazias isso indica que as configurações dos experimentos não influenciam nos mecanimos ativos pelos compostos."
      ]
    }
  ]
}