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DESCRIPTION
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DESCRIPTION
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Package: progeny
Title: Pathway RespOnsive GENes for activity inference from gene expression
Version: 1.17.3
Authors@R: c(
person(given = "Michael",
family = "Schubert",
role = "aut"),
person(given = "Alberto",
family = "Valdeolivas",
role = "ctb",
email = "[email protected]",
comment = c(ORCID = "0000-0001-5482-9023")),
person(given = "Christian H.",
family = "Holland",
role = "ctb",
email = "[email protected]",
comment = c(ORCID = "0000-0002-3060-5786")),
person(given = "Igor",
family = "Bulanov",
role = "ctb"),
person(given = "Aurélien",
family = "Dugourd",
role = c("cre","ctb"),
email = "[email protected]")
)
Description: PROGENy is resource that leverages a large compendium of publicly available signaling perturbation experiments to yield a common core of pathway responsive genes for human and mouse. These, coupled with any statistical method, can be used to infer pathway activities from bulk or single-cell transcriptomics.
URL: https://github.com/saezlab/progeny
BugReports: https://github.com/saezlab/progeny/issues
Depends:
R (>= 3.6.0)
Imports:
Biobase,
stats,
dplyr,
tidyr,
ggplot2,
ggrepel,
gridExtra,
decoupleR,
reshape2
biocViews: SystemsBiology, GeneExpression, FunctionalPrediction, GeneRegulation
License: Apache License (== 2.0) | file LICENSE
LazyData: true
LazyDataCompression: bzip2
Encoding: UTF-8
Suggests:
airway,
biomaRt,
BiocFileCache,
broom,
Seurat,
SingleCellExperiment,
DESeq2,
BiocStyle,
knitr,
readr,
readxl,
pheatmap,
tibble,
rmarkdown,
testthat (>= 2.1.0)
VignetteBuilder: knitr
RoxygenNote: 7.2.2