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XBB.1.41.1 (S:335S,403K,478R) sublineage with Orf1a:P1220L and N:H300Y growing internationally (251, > 7% in Louisaina in September) #629
Comments
This is flying in Louisiana ( 10% there both in last two weeks of July and the first two of August) |
@corneliusroemer i was looking at epi in Louisiana it seems quite fastly growing with this lineage at 10% but XBB.1.41 there. And with XBB.1.41.2 they together reach around 17-18% in August (over 100 samples) while S:F456L seems still far at less than 7-8% https://twitter.com/BNOFeed/status/1694484633365189061 I suggest to designate this one too also for the possible N-GTF due to N:300 mutated. |
new samples Wi, NY |
67 tot. Many international samples beyond US. |
68 prevalence in Louisiana seems less than before but anyway around 10% |
Sorry it is JC.5. I commented in a wrong place |
JC.5 |
Designated JC.5 via cov-lineages/pango-designation@d3d7c09 |
Thank you @ryhisner ! great spot! i noticed that JC.5.1 did a noticeable comeback in collection 42 just yesterday evening, i left this tab open on my pc when falling asleep and this morning i found your comment! This is something to watch closely, in my view. Do you think all the JC.5.1 sequences have the Orf7a deletion? but likely not everyone has the new orf7b right? |
Thanks to a question from Marc Johnson if there wer some sublineage with N2 gene test failure i found this one, maybe it is not related with the question but for sure it is expanding in US and Uk during last month.
Defining mutations:
XBB.1.41.1(S:335S,403K,478R) >> C364T > Orf1a:P1220L (C3924T = NSP3_P402L), C18555T > N:H300Y (C29171T)
Gisaid query: ,C3924T,C18555T,C364T
Samples 35 From Usa(Alabama) , UK , Ireland, Israel , Australia
IDs
EPI_ISL_17974948, EPI_ISL_17989726, EPI_ISL_18012574, EPI_ISL_18036936, EPI_ISL_18053693, EPI_ISL_18053723, EPI_ISL_18053726-18053727, EPI_ISL_18053733, EPI_ISL_18053740, EPI_ISL_18053746, EPI_ISL_18053756, EPI_ISL_18053758, EPI_ISL_18053760, EPI_ISL_18056768, EPI_ISL_18057661, EPI_ISL_18060387, EPI_ISL_18060397, EPI_ISL_18065807, EPI_ISL_18072072-18072073, EPI_ISL_18072081, EPI_ISL_18072093, EPI_ISL_18092135, EPI_ISL_18095045, EPI_ISL_18097938, EPI_ISL_18097940, EPI_ISL_18097942, EPI_ISL_18097944, EPI_ISL_18097953, EPI_ISL_18097964, EPI_ISL_18099263, EPI_ISL_18104449, EPI_ISL_18107756, EPI_ISL_18108106,Tree:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_35258_e2a400.json?c=gt-N_300&label=id:node_7003861
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