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XBB.1.5.70+S:N556K,E583A(51 seqs, 5 countries) #715

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aviczhl2 opened this issue Aug 29, 2023 · 7 comments
Closed

XBB.1.5.70+S:N556K,E583A(51 seqs, 5 countries) #715

aviczhl2 opened this issue Aug 29, 2023 · 7 comments
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combo It has a couple of mutation in RBD designated FLip = S:L455F / S:F456L S:556 S:583
Milestone
GK.6

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@aviczhl2
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aviczhl2 commented Aug 29, 2023 •
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XBB.1.5.70+A20304G, C23230A, A23310C, G29440A(S:N556K,E583A)

GISAID query: A20304G, A23310C,G29440A
No. of seqs: 16(USA 13 Switzerland 2 France 1 )

First: EPI_ISL_17790148,Switzerland, 2023-5-30
Latest: EPI_ISL_18144445, USA, 2023-8-18

usher

image
@aviczhl2 aviczhl2 changed the title XBB.1.5.70+S:N556K,E583D(16 seqs, 3 countries) XBB.1.5.70+S:N556K,E583A(16 seqs, 3 countries) Aug 29, 2023
@FedeGueli FedeGueli added FLip = S:L455F / S:F456L S:583 S:556 combo It has a couple of mutation in RBD labels Aug 29, 2023
@aviczhl2
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18, Canada

@aviczhl2 aviczhl2 changed the title XBB.1.5.70+S:N556K,E583A(16 seqs, 3 countries) XBB.1.5.70+S:N556K,E583A(18 seqs, 4 countries) Aug 30, 2023
@aviczhl2 aviczhl2 changed the title XBB.1.5.70+S:N556K,E583A(18 seqs, 4 countries) XBB.1.5.70+S:N556K,E583A(20 seqs, 4 countries) Sep 7, 2023
@aviczhl2 aviczhl2 changed the title XBB.1.5.70+S:N556K,E583A(20 seqs, 4 countries) XBB.1.5.70+S:N556K,E583A(23 seqs, 4 countries) Sep 14, 2023
@FedeGueli FedeGueli changed the title XBB.1.5.70+S:N556K,E583A(23 seqs, 4 countries) XBB.1.5.70+S:N556K,E583A(24 seqs, 4 countries) Sep 17, 2023
@FedeGueli
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Not fast.

@aviczhl2 aviczhl2 changed the title XBB.1.5.70+S:N556K,E583A(24 seqs, 4 countries) XBB.1.5.70+S:N556K,E583A(30 seqs, 4 countries) Sep 21, 2023
@aviczhl2 aviczhl2 changed the title XBB.1.5.70+S:N556K,E583A(30 seqs, 4 countries) XBB.1.5.70+S:N556K,E583A(33 seqs, 4 countries) Sep 26, 2023
@aviczhl2 aviczhl2 changed the title XBB.1.5.70+S:N556K,E583A(33 seqs, 4 countries) XBB.1.5.70+S:N556K,E583A(39 seqs, 4 countries) Sep 30, 2023
@aviczhl2 aviczhl2 changed the title XBB.1.5.70+S:N556K,E583A(39 seqs, 4 countries) XBB.1.5.70+S:N556K,E583A(44 seqs, 4 countries) Oct 4, 2023
@FedeGueli
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I m curious to see how it works outside NYC. looking at collection date it seems faster than looking at submission date

@aviczhl2 aviczhl2 changed the title XBB.1.5.70+S:N556K,E583A(44 seqs, 4 countries) XBB.1.5.70+S:N556K,E583A(45 seqs, 4 countries) Oct 8, 2023
@aviczhl2
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51, one USA sample is from Turkey

@aviczhl2 aviczhl2 changed the title XBB.1.5.70+S:N556K,E583A(45 seqs, 4 countries) XBB.1.5.70+S:N556K,E583A(51 seqs, 5 countries) Oct 12, 2023
@FedeGueli
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growing but slower than competitors : https://cov-spectrum.org/explore/World/AllSamples/Past3M/variants?nextcladePangoLineage=HK.3*&nucMutations1=A20304G%2CA23310C%2CG29440A&analysisMode=CompareToBaseline&

@FedeGueli FedeGueli added It can not compete It means it has growth disadvantage versus dominant lineages but worth tracking and removed Rapid review needed labels Oct 12, 2023
@aviczhl2
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Designated GK.6 @FedeGueli

@FedeGueli FedeGueli added designated and removed It can not compete It means it has growth disadvantage versus dominant lineages but worth tracking labels Oct 15, 2023
@FedeGueli FedeGueli added this to the GK.6 milestone Oct 15, 2023
@FedeGueli
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GK.6 from cov-lineages/pango-designation@6fe25ac

FedeGueli referenced this issue in cov-lineages/pango-designation Oct 15, 2023
@corneliusroemer
Designate GK.6 (XBB.1.5.70.6, S:N556K, S:E583A) with 50 seqs
6fe25ac
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combo It has a couple of mutation in RBD designated FLip = S:L455F / S:F456L S:556 S:583
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