From 8589683be1bee827f7cac2b1a6cf3603a704fdb1 Mon Sep 17 00:00:00 2001
From: Alex Ostrovsky <40246333+astrovsky01@users.noreply.github.com>
Date: Mon, 26 Aug 2024 12:12:01 -0700
Subject: [PATCH] Fix broken link to Watson and Crick paper
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README.md | 2 +-
1 file changed, 1 insertion(+), 1 deletion(-)
diff --git a/README.md b/README.md
index b95704a..16efa79 100644
--- a/README.md
+++ b/README.md
@@ -43,7 +43,7 @@ We will study the leading computational and quantitative approaches for comparin
| Class | Date | Day | Topic | Assignments | Readings |
| ----- | ------ | --- | --------------------------------------------------------------- | ----------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
-| 1 | 26-Aug | Mon | Introduction | [Sign Up for Piazza](https://piazza.com/jhu/fall2024/600449600649/home) | \* [Molecular Structure of Nucleic Acid (Watson and Crick, 1953, Nature)](http://www.nature.com/nature/dna50/watsoncrick.pdf)
\* [Biological data sciences in genome research (Schatz, 2015, Genome Research)](http://genome.cshlp.org/content/25/10/1417.full)
\* [Big Data: Astronomical or Genomical? (Stephens et al, 2015, PLOS Biology)](http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002195) |
+| 1 | 26-Aug | Mon | Introduction | [Sign Up for Piazza](https://piazza.com/jhu/fall2024/600449600649/home) | \* [Molecular Structure of Nucleic Acid (Watson and Crick, 1953, Nature)](https://www.nature.com/articles/171737a0)
\* [Biological data sciences in genome research (Schatz, 2015, Genome Research)](http://genome.cshlp.org/content/25/10/1417.full)
\* [Big Data: Astronomical or Genomical? (Stephens et al, 2015, PLOS Biology)](http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002195) |
| 2 | 28-Aug | Wed | Genomic Technologies, kmers | Assignment 1 | \* [Coming of age: ten years of next-generation sequencing technologies (Goodwin et al, 2016, Nature Reviews Genetics)](http://www.nature.com/nrg/journal/v17/n6/full/nrg.2016.49.html)
\* [Guide to k-mer approaches for genomics across the tree of life (Jenike et al., 2024, arXiv)](https://arxiv.org/abs/2404.01519) |
| \* | 2-Sep | Mon | $${\color{red}\text{Labor Day}}$$ | | |
| 3 | 4-Sep | Wed | Assembly, WGA | | \* [Toward simplifying and accurately formulating fragment assembly. (Myers, 1995, J. Comp. Bio.)](http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.52.6330&rep=rep1&type=pdf)
\* [Velvet: Algorithms for de novo short read assembly using de Bruijn graphs (Zerbino and Birney, 2008, Genome Research)](http://genome.cshlp.org/content/18/5/821.full)
\* [SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing (Bankevich, et al. 2012, J Comput Biol)](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342519/)
\* [MUMmer: Alignment of Whole Genomes (Delcher et al, 1999, NAR)](http://mummer.sourceforge.net/MUMmer.pdf) |