diff --git a/src/coreclr/interop/comwrappers.cpp b/src/coreclr/interop/comwrappers.cpp
index 095f098e286015..96f47a0f040602 100644
--- a/src/coreclr/interop/comwrappers.cpp
+++ b/src/coreclr/interop/comwrappers.cpp
@@ -736,7 +736,16 @@ HRESULT ManagedObjectWrapper::QueryInterface(
                     return E_NOINTERFACE;
 
                 default:
-                    _ASSERTE(false && "Unknown result value");
+                    // NOTE: here the `result == *` of assert is just for avoiding the compiling error
+                    // `fallthrough annotation in unreachable code` within debug mode using clang <=13.
+                    // Because clang versions before 14 had a bug here.
+                    _ASSERTE(
+#if defined(__clang__) && (__clang_major__ < 14)
+                            (result == TryInvokeICustomQueryInterfaceResult::FailedToInvoke)
+#else
+                            false
+#endif
+                            && "Unknown result value");
                     FALLTHROUGH;
                 case TryInvokeICustomQueryInterfaceResult::FailedToInvoke:
                     // Set the 'lacks' flag since our attempt to use ICustomQueryInterface
diff --git a/src/coreclr/pal/inc/pal.h b/src/coreclr/pal/inc/pal.h
index 9a1d25515bb32e..70b934a8ccd88e 100644
--- a/src/coreclr/pal/inc/pal.h
+++ b/src/coreclr/pal/inc/pal.h
@@ -184,14 +184,6 @@ extern bool g_arm64_atomics_present;
 #define __has_cpp_attribute(x) (0)
 #endif
 
-#ifndef FALLTHROUGH
-#if __has_cpp_attribute(fallthrough)
-#define FALLTHROUGH [[fallthrough]]
-#else // __has_cpp_attribute(fallthrough)
-#define FALLTHROUGH
-#endif // __has_cpp_attribute(fallthrough)
-#endif // FALLTHROUGH
-
 /******************* PAL-Specific Entrypoints *****************************/
 
 #define IsDebuggerPresent PAL_IsDebuggerPresent