From 441aecbf24258144f9a53bab35604a6d265499cb Mon Sep 17 00:00:00 2001 From: Hanna Date: Fri, 16 Nov 2018 19:54:30 -0500 Subject: [PATCH] Update README.md note about numba relase --- README.md | 4 ++++ 1 file changed, 4 insertions(+) diff --git a/README.md b/README.md index 5baaa4e..26d69b1 100644 --- a/README.md +++ b/README.md @@ -1,5 +1,9 @@ # Single-cell Hierarchical Poisson Factorization +## Update +A newer version of the code, which uses numba and is substantially more computationally effiecient is available on branch rewrite_release. It will be merged into master shortly. + +## About Pre-release of [Single-cell Hierarchical Poisson Factorization (scHPF)](https://www.biorxiv.org/content/early/2018/07/11/367003), as described in the forthcoming manuscript:
*De novo* Gene Signature Identification from Single-Cell RNA-Seq with Hierarchical Poisson Factorization. scHPF is a tool for _de novo_ discovery of both discrete and continuous expression patterns in single-cell RNA\-sequencing (scRNA-seq) data. It adapts [Hierarchical Poisson Factorization](http://www.cs.columbia.edu/~blei/papers/GopalanHofmanBlei2015.pdf) to avoid prior normalization and model variable sparsity across genes and cells. Algorithmic details, benchmarking against alternative methods, and scHPF's application to a spatially sampled high-grade glioma can be found in our [paper on biorXiv](https://www.biorxiv.org/content/early/2018/07/11/367003).