diff --git a/src/dotenv/main.py b/src/dotenv/main.py
index 383b79f4..20c7782e 100644
--- a/src/dotenv/main.py
+++ b/src/dotenv/main.py
@@ -280,7 +280,10 @@ def find_dotenv(
 
     def _is_interactive():
         """ Decide whether this is running in a REPL or IPython notebook """
-        main = __import__('__main__', None, None, fromlist=['__file__'])
+        try:
+            main = __import__('__main__', None, None, fromlist=['__file__'])
+        except ModuleNotFoundError:
+            return False
         return not hasattr(main, '__file__')
 
     if usecwd or _is_interactive() or getattr(sys, 'frozen', False):