diff --git a/azure-pipelines.yml b/azure-pipelines.yml
index 7bad2ca92c7..8c0b01a731a 100644
--- a/azure-pipelines.yml
+++ b/azure-pipelines.yml
@@ -93,12 +93,12 @@ jobs:
         - tokio-no-features
         - tokio-with-net
 
-# # Try cross compiling
-# - template: ci/azure-cross-compile.yml
-#   parameters:
-#     name: cross_32bit_linux
-#     target: i686-unknown-linux-gnu
-#
+# Try cross compiling
+- template: ci/azure-cross-compile.yml
+  parameters:
+    name: cross
+    rust: $(nightly)
+
 # # This represents the minimum Rust version supported by
 # # Tokio. Updating this should be done in a dedicated PR and
 # # cannot be greater than two 0.x releases prior to the
@@ -127,6 +127,6 @@ jobs:
       - test_linux
       - test_features
 #      - test_nightly
-#      - cross_32bit_linux
+      - cross
 #      - minrust
 #      - tsan
diff --git a/ci/azure-cross-compile.yml b/ci/azure-cross-compile.yml
index 8c2553c726d..f0e83f03162 100644
--- a/ci/azure-cross-compile.yml
+++ b/ci/azure-cross-compile.yml
@@ -1,27 +1,41 @@
 jobs:
 - job: ${{ parameters.name }}
   displayName: ${{ parameters.displayName }}
+  strategy:
+    matrix:
+      i686:
+        vmImage: ubuntu-16.04
+        target: i686-unknown-linux-gnu
+      powerpc:
+        vmImage: ubuntu-16.04
+        target: powerpc-unknown-linux-gnu
+      powerpc64:
+        vmImage: ubuntu-16.04
+        target: powerpc64-unknown-linux-gnu
+      mips:
+        vmImage: ubuntu-16.04
+        target: mips-unknown-linux-gnu
   pool:
-    vmImage: ubuntu-16.04
+    vmImage: $(vmImage)
   steps:
   - template: azure-install-rust.yml
     parameters:
-      rust_version: stable
+      rust_version: ${{ parameters.rust }}
 
   - script: sudo apt-get update
-    displayName: "apt-get update"
+    displayName: apt-get update
 
   - script: sudo apt-get install gcc-multilib
-    displayName: "Install gcc-multilib"
+    displayName: Install gcc-multilib
 
-  - script: rustup target add ${{ parameters.target }}
-    displayName: "Add target"
+  - script: cargo install cross
+    displayName: Install cross
 
   # Always patch
   - template: azure-patch-crates.yml
 
-  - script: cargo check --all --exclude tokio-tls --target ${{ parameters.target }}
+  - script: cross check --all --exclude tokio-tls --target $(target)
     displayName: Check source
 
-  - script: cargo check --tests --all --exclude tokio-tls --target ${{ parameters.target }}
-    displayName: Check tests
+  # - script: cross check --tests --all --exclude tokio-tls --target $(target)
+  #   displayName: Check tests
diff --git a/tokio-timer/src/atomic.rs b/tokio-timer/src/atomic.rs
index 3ec7b2f8919..6a592edb4aa 100644
--- a/tokio-timer/src/atomic.rs
+++ b/tokio-timer/src/atomic.rs
@@ -4,12 +4,15 @@
 
 pub(crate) use self::imp::AtomicU64;
 
-#[cfg(target_pointer_width = "64")]
+// `AtomicU64` can only be used on targets with `target_has_atomic` is 64 or greater.
+// Once `cfg_target_has_atomic` feature is stable, we can replace it with
+// `#[cfg(target_has_atomic = "64")]`.
+#[cfg(not(any(target_arch = "mips", target_arch = "powerpc")))]
 mod imp {
     pub(crate) use std::sync::atomic::AtomicU64;
 }
 
-#[cfg(not(target_pointer_width = "64"))]
+#[cfg(any(target_arch = "mips", target_arch = "powerpc"))]
 mod imp {
     use std::sync::atomic::Ordering;
     use std::sync::Mutex;