diff --git a/packages/vite/src/node/server/transformRequest.ts b/packages/vite/src/node/server/transformRequest.ts
index 5dc6e3921215af..94e8c124041077 100644
--- a/packages/vite/src/node/server/transformRequest.ts
+++ b/packages/vite/src/node/server/transformRequest.ts
@@ -183,9 +183,14 @@ async function doTransform(
     resolved,
   )
 
-  const depsOptimizer = getDepsOptimizer(config, ssr)
-  if (!depsOptimizer?.isOptimizedDepFile(id)) {
-    server._registerRequestProcessing(id, () => result)
+  if (!ssr) {
+    // Only register client requests, server.waitForRequestsIdle should
+    // have been called server.waitForClientRequestsIdle. We can rename
+    // it as part of the environment API work
+    const depsOptimizer = getDepsOptimizer(config, ssr)
+    if (!depsOptimizer?.isOptimizedDepFile(id)) {
+      server._registerRequestProcessing(id, () => result)
+    }
   }
 
   return result