muSignAl: multiple Signature Algorithm

An R package for detecting multiple signatures with similar predictive performance.

Code author/maintainer: @bodhayan

Visit us at: Shukla Lab

Requirements

muSignAl was coded in R v3.6, and require a couple of packages (glmnet and pROC) to be pre-installed, which can be installed as below:

install.packages(c("glmnet","pROC"))

Installation

To install the latest version of muSignAl, please follow the steps:

install.packages("devtools")
devtools::install_github("ShuklaLab/muSignAl")

To update the package just run the same command again.

Sample run

A test script (test.R), ran on a sample dataset (AD.xlsx) and its final output (sign_cvd2.xlsx) are present in the example folder.

Contributing and licensing

MIT License is free license software and grants the software end user rights such as copying, modifying, merging, distributing, etc.

Pull requests are welcome. For major changes, please open an issue first to discuss what you would like to change.

Publication

If you're using muSignAl, please cite:

Prasad B, Bjourson AJ, Shukla P. muSignAl: An algorithm to search for multiple omic signatures with similar predictive performance. Proteomics. 2023 Jan;23(2):e2200252. doi: 10.1002/pmic.202200252. Epub 2022 Oct 3. PMID: 36076312.

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Last updated on: 18 Jan 2023