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Vini2/README.md

Hi there 👋

I’m Vijini Mallawaarachchi—I’m a Research Associate in Bioinformatics at the Flinders Accelerator for Microbiome Exploration, Flinders University. I enjoy developing algorithms, writing code, reading and blogging.

My current research work is focused on algorithms and computational models related to the construction of metagenome-assembled genomes (MAGs). Metagenomics involves the study of genetic material obtained from the genomes found in microbial communities. A microbial community can contain a large number of organisms. My work focuses on developing methods and tools to investigate the taxonomic structure of a given metagenomic sample.

Repo Highlights

The first automated tool to make use of assembly graphs to refine binning results from existing metagenomic contig-binning tools.

Next generation of GraphBin that refines binning results from existing metagenomic contig-binning tools using assembly graphs. GraphBin2 also assigns contigs to multiple bins if they are shared between different species.

The first stand-alone metagenomic contig-binning tool that makes use of assembly graphs apart from composition and coverage information for binning.

Resolving high-quality bacteriophage genomes from fragmented assemblies of viral metagenomic data using graph algorithms and flow decomposition techniques.

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  1. metagentools/GraphBin metagentools/GraphBin Public

    ✨🧬 Refined binning of metagenomic contigs using assembly graphs

    Python 89 7

  2. phables phables Public

    🫧🧬 From fragmented assemblies to high-quality bacteriophage genomes

    Python 74 6

  3. metagentools/MetaCoAG metagentools/MetaCoAG Public

    🚦🧬 Binning Metagenomic Contigs via Composition, Coverage and Assembly Graphs

    Python 59 5

  4. metagentools/GraphBin2 metagentools/GraphBin2 Public

    ☯️🧬 Refined and Overlapped Binning of Metagenomic Contigs Using Assembly Graphs

    Python 33 3

  5. reneo reneo Public

    🦠🧬 Unraveling Viral Genomes from Metagenomes

    Python 10 2

  6. metagentools/ConDiGA metagentools/ConDiGA Public

    🗂️🧬 Contigs directed gene annotation for accurate protein sequence database construction in metaproteomics

    Python 5 1