BMDExpress 2.30 Bug Fix

Fixed an issue flagging hill models when BMD is below the lowest dose. Previously the application interpreted 1/3 as 1/4 and 1/2 as 1/3 due to a bug creating the flag hill ratio value.

BMDExpress 2.30 Bug Fix

• Fixed issue when running multiple One Way Anova analyses causing LOTEL/NOTEL
  calculation to shuffle p-value and fold change parameters in GUI. This was not an issue when running one dataset at a time and in the command line version
• Fixed issue cause by invalid default folder path for exporting and importing data.

BMDExpress 2.3 OpenJDK 11 July 2020

BMDExpress2.3 is now compatible with OpenJDK 11. The software is no longer compatible with Java 8.

BMDExpress 2.3 Bug Fixes June 2020

• When the user selected and specified a value for "Remove Genes with BMD/BMDL >" AND/OR "Remove Genes with BMDU/BMD >" to filter out genes while filling out the input form for Functional Classification, the user specified value(s) were actually compared to BMDU/BMDL of the Best Model for the BMD Analysis result for the gene/probe. This issue has been corrected.

• The first two non-header lines of the category input file were being ignored when performing Defined Category Analysis. This issue has been fixed.

BMDExpress 2.3

• IVIVE analysis over 700,000 chemicals and properties using HTTK
• Sciome GCurveP for non-parametric dose-response modeling
• LOTEL/NOTEL calculation using Dunnett’s test or Student T-Test
• Individual gene category analysis
• Integration of BioPlanet into the Signaling Pathway Analysis
• Hide/Show table columns
• Copy/Paste table rows
• Venn diagram chart viewer for prefilter analysis results
• Density charts for expression data visual QC
• Violin Plots for visualizing category analysis results

BMDExpress 2.2

This release addresses one bug:

1. The Williams Trend Test returned p-values greater than 1 for genes that had little to no signal. This caused the genes to pass the filter even when the user selected "None" for p-value in prefilter window. This problem has been fixed.

BMDExpress 2.2

This release addresses two bugs.

1. Select Best Poly Model via lowest AIC has been broken since version 1. This release fixes that issue.
2. The command line version two options to flag hill at 1/2 or 1/3 lowest positive dose.

BMDExpress 2.2

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updated version.txt to represent recent command line enhancements

BMDExpress 2.0: First Release

You can now download the latest installer for Windows, Mac and Linux. The application will periodically perform automatic updates so you can easily gain access to new features and bug fixes. Currently the Mac and Linux versions does not allow you to run BMD Analysis nor do they allow you to perform One Way ANOVA filtering. They do allow you to view .bm2 files as well as perform functional classification on existing BMD analyses. If you are running the software on a Linux machine, then please ensure that the latest version of Java is installed and available to the application. The installation package contains an embedded Java installation for the Windows and Mac versions.